TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataKi: 0.75nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis inhAMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: <0.5nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: <0.5nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: <0.5nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 0.700nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 1nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 1.30nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 2nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 4nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: <5nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 5nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 6nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 7nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 7nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 8nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 8nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 8nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 8nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 9nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 10nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 10nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 11nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 13nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis inhAMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Mycobacterium tuberculosis InhA using NADH and dodecyl coA substrate by LC-MS/MS methodMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 50nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 101nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 188nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair