Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 26nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 31nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 38nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 38nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 40nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 190nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Affinity DataIC50: 209nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 219nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Affinity DataIC50: 257nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 290nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 372nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 410nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Affinity DataIC50: 417nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 417nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 427nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 427nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 427nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 437nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 530nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
Affinity DataIC50: 562nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 562nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 562nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 631nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 676nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 776nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 813nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 930nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Log of inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair