Compile Data Set for Download or QSAR
maximum 50k data
Found 155 with Last Name = 'hibi' and Initial = 's'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)
Affinity DataKi:  8.30nMAssay Description:Antagonist activity at human CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420920(CHEMBL2087549 | CHEMBL2087567)
Affinity DataKi:  11nMAssay Description:Antagonist activity at human CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420920(CHEMBL2087549 | CHEMBL2087567)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human CRF2 receptor expressed in IMR32 cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084833(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50:  0.450nMAssay Description:Binding affinity for Retinoic Acid Receptor alpha (RAR alpha)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataIC50:  0.620nMAssay Description:Binding affinity against Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataIC50:  0.890nMAssay Description:Binding affinity for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRetinoic acid receptor beta(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataIC50:  0.940nMAssay Description:Binding affinity for Retinoic acid receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037039(2-Amino-5,7-dimethyl-4-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084832(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  2nMAssay Description:Binding affinity for Retinoic Acid Receptor gamma (RAR gamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084835(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  2.20nMAssay Description:Binding affinity for Retinoic Acid Receptor alpha (RAR alpha)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084832(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity for Retinoic Acid Receptor alpha (RAR alpha)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084834(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity for Retinoic Acid Receptor beta (RAR beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084830(4-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  3.60nMAssay Description:Binding affinity for Retinoic Acid Receptor gamma (RAR gamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084832(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  4.5nMAssay Description:Binding affinity for Retinoic Acid Receptor beta (RAR beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084831(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  4.60nMAssay Description:Binding affinity for Retinoic Acid Receptor gamma (RAR gamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50398565(CHEMBL2179195)
Affinity DataIC50:  7.10nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420904(CHEMBL2087550)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037040(2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420906(CHEMBL2087552)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420908(CHEMBL2087554)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420909(CHEMBL2087555)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420905(CHEMBL2087551)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084829(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  17nMAssay Description:Binding affinity for Retinoic Acid Receptor gamma (RAR gamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084834(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  19nMAssay Description:Binding affinity for Retinoic Acid Receptor alpha (RAR alpha)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420916(CHEMBL2087562)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420912(CHEMBL2087558)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084830(4-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  21nMAssay Description:Binding affinity for Retinoic Acid Receptor beta (RAR beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084833(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50:  21nMAssay Description:Binding affinity for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420915(CHEMBL2087561)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420916(CHEMBL2087562)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420920(CHEMBL2087549 | CHEMBL2087567)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420907(CHEMBL2087553)
Affinity DataIC50:  24nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420930(CHEMBL2087795)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084834(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  27nMAssay Description:Binding affinity for Retinoic Acid Receptor gamma (RAR gamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420935(CHEMBL2087799)
Affinity DataIC50:  27nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420927(CHEMBL2087574)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50037044(4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...)
Affinity DataIC50:  30nMAssay Description:Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50099474(4-[5-(8-Isopropyl-4-phenyl-quinolin-2-yl)-1H-pyrro...)
Affinity DataIC50:  31nMAssay Description:Antagonistic activity of the compound was evaluated in terms of inhibition of Retinoic acid receptor alpha transactivation by ATRA (50 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084831(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  32nMAssay Description:Binding affinity for Retinoic Acid Receptor alpha (RAR alpha)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420914(CHEMBL2087560)
Affinity DataIC50:  34nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420937(CHEMBL2087801)
Affinity DataIC50:  34nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420927(CHEMBL2087574)
Affinity DataIC50:  35nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50084829(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50:  36nMAssay Description:Binding affinity for Retinoic Acid Receptor beta (RAR beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420913(CHEMBL2087559)
Affinity DataIC50:  38nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420931(CHEMBL2087796)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 155 total ) | Next | Last >>
Jump to: