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Found 139 with Last Name = 'hobbs' and Initial = 'pd'
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50151228(6-[Cyclopropylidene-(5,5,8,8-tetramethyl-3-propoxy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to human retinoid X receptor alpha ligand-binding domain expressed in E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50151230(6-[(3-Butoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to human retinoid X receptor alpha ligand-binding domain expressed in E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50151229(4-[Cyclopropylidene-(3,5,5,8,8-pentamethyl-5,6,7,8...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to human retinoid X receptor alpha ligand-binding domain expressed in E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataIC50:  29nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to human retinoid X receptor alpha ligand-binding domain expressed in E. coliMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50151231(4-[Cyclopropylidene-(5,5,8,8-tetramethyl-3-propoxy...)
Affinity DataIC50:  120nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to human retinoid X receptor alpha ligand-binding domain expressed in E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50151227(4-[(3-Butoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydr...)
Affinity DataIC50:  270nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to human retinoid X receptor alpha ligand-binding domain expressed in E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25127((2E)-3-{3-chloro-4-[3-(3,3-dimethylbut-1-yn-1-yl)-...)
Affinity DataIC50:  450nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50151226(4-[(3-Butyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro...)
Affinity DataIC50:  500nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to human retinoid X receptor alpha ligand-binding domain expressed in E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase receptor type C-associated protein(Homo sapiens (Human))
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50212333(5-[3'-(1-adamantyl)-2-chloro-4'-hydroxy-4-biphenyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of CD45 PTP by fluorescence spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50212333(5-[3'-(1-adamantyl)-2-chloro-4'-hydroxy-4-biphenyl...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of SHP2 PTP by fluorescence spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25124((2E)-3-{4-[3-(adamantan-1-yl)-4-aminophenyl]-3-chl...)
Affinity DataIC50:  1.83E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25122((2E)-3-{4-[3-(adamantan-1-yl)-4-hydroxyphenyl]-3-c...)
Affinity DataIC50:  2.10E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25125((2E)-3-{4-[3-(adamantan-1-yl)-4-fluorophenyl]-3-ch...)
Affinity DataIC50:  2.11E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50212331(5-[1-(3'-adamantan-1-yl-2-chloro-4'-hydroxy-biphen...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of SHP2 PTP by fluorescence spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25131((2E)-3-{3-chloro-4-[3-(3,5-dimethyladamantan-1-yl)...)
Affinity DataIC50:  2.27E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase receptor type C-associated protein(Homo sapiens (Human))
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50212331(5-[1-(3'-adamantan-1-yl-2-chloro-4'-hydroxy-biphen...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CD45 PTP by fluorescence spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25129((2E)-3-[3-chloro-4-(4-hydroxy-3-{tricyclo[3.3.1.0^...)
Affinity DataIC50:  3.91E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25123((2E)-3-{4-[3-(adamantan-1-yl)-4-acetamidophenyl]-3...)
Affinity DataIC50:  4.55E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25133((2E)-3-{3-chloro-4-[3-(3-ethylpentan-3-yl)-4-hydro...)
Affinity DataIC50:  5.37E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25130((2E)-3-{3-chloro-4-[4-hydroxy-3-(1-methylcyclohexy...)
Affinity DataIC50:  6.40E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25132((2E)-3-{3-chloro-4-[4-hydroxy-3-(2-methyl-1,3-dith...)
Affinity DataIC50:  1.02E+4nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25128((2E)-3-{3-chloro-4-[3-(2,6-dimethylphenyl)-4-hydro...)
Affinity DataIC50:  1.99E+4nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM25126((2E)-3-[3-chloro-4-(4-fluorophenyl)phenyl]prop-2-e...)
Affinity DataIC50:  5.00E+5nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033075(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  630nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033070(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  750nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033063(4-[(Z)-1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  55nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033066(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataEC50:  530nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033062(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033063(4-[(Z)-1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  160nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50032667(4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataEC50:  360nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50032667(4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataEC50:  1.20E+3nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033064(4-[(E)-1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033065((2E,4E)-3,7-Dimethyl-6-(5,5,8,8-tetramethyl-5,6,7,...)
Affinity DataEC50:  33nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033065((2E,4E)-3,7-Dimethyl-6-(5,5,8,8-tetramethyl-5,6,7,...)
Affinity DataEC50:  380nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033066(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataEC50:  3.20E+3nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033063(4-[(Z)-1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  370nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  42nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50032667(4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataEC50:  210nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  2.60nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033067(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  170nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataEC50:  2nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  112nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033068((2E,4E)-3-Methyl-5-[2-(3,5,5,8,8-pentamethyl-5,6,7...)
Affinity DataEC50:  2.30E+3nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033069((2E,4E)-3,7-Dimethyl-6-(3,5,5,8,8-pentamethyl-5,6,...)
Affinity DataEC50:  140nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033064(4-[(E)-1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  1.60E+3nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033071(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  180nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataEC50:  530nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50033066(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataEC50:  1.70E+3nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50033072(4-[Hydroxy-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  2.90E+3nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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