Affinity DataKi: 0.160nMAssay Description:Compound was tested for the inhibition of [3H]prazosin binding Alpha-1 adrenergic receptor of crude rat brain membrane.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Compound was tested for the inhibition of [3H]clonidine binding Alpha-2 adrenergic receptor of crude rat brain membraneMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity towards [3H]Fnz in alpha-1-beta-2-gamma-2 subtype was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to human recombinant P2Y12 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pharmacia & Upjohn
Curated by PDSP Ki Database
Pharmacia & Upjohn
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Pharmacia & Upjohn
Curated by PDSP Ki Database
Pharmacia & Upjohn
Curated by PDSP Ki Database
Affinity DataKi: 4nMAssay Description:Compound was tested for the inhibition of [3H]prazosin binding Alpha-2 adrenergic receptor of crude rat brain membrane.More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to human recombinant P2Y12 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of HIV-1 protease in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Compound was tested for the inhibition of [3H]prazosin binding alpha-1-adrenergic receptor of crude rat brain membrane.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of HIV-1 protease in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of HIV-1 protease in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity to human recombinant P2Y12 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]Ro-154513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6-beta-2-gamma-2 GABA-A receptor subunits expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pharmacia & Upjohn
Curated by PDSP Ki Database
Pharmacia & Upjohn
Curated by PDSP Ki Database
Affinity DataKi: 7.20nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to human recombinant P2Y12 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of HIV-1 protease in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Binding affinity of [3H]-spiperone towards cloned mammalian Dopamine receptor D4 expressed in cultured cells or from rat whole brainMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Compound was tested for the inhibition of [3H]clonidine binding Alpha-2 adrenergic receptor of crude rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Compound was tested for the inhibition of [3H]prazosin binding Alpha-1 adrenergic receptor of crude rat brain membrane.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to human recombinant P2Y12 receptor expressed in CHO cell membrane in presence of HSA and human AGPMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of HIV-1 protease in vitro.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-Ro-15-4513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]flunitrazepam from GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of HIV-1 protease in vitro.More data for this Ligand-Target Pair