TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Allergan
Curated by ChEMBL
Allergan
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of EGF-dependent proliferation of human and guinea pig keratinocytes; range 7-15 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of EGF-dependent proliferation of human and guinea pig keratinocytes; range 7-15 uMMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity of the compound was determined for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor alpha; Not activeMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity of the compound was determined for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity of the compound was determined for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 2.30E+3nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 54nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding affinity of the compound was determined for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 260nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-betaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 2.5nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0800nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 6.20E+3nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-betaMore data for this Ligand-Target Pair
Affinity DataEC50: >500nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataKd: >10nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-gammaMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 9.50E+3nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataKd: 1.80nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
Affinity DataKd: 3.80nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 210nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
Affinity DataEC50: >500nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 5.75E+3nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
Affinity DataKd: >30nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-gammaMore data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
Affinity DataEC50: >500nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair