TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Antagonistic activity of the compound against LTB4 receptor using guinea pig (GP) spleen cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nM Koff: 4.45E+4s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM Koff: 9.40E+4s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM Koff: 4.90E+4s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM Koff: 9.40E+4s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM Koff: 1.00E+5s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 2nM Koff: 5.40E+4s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 2nM Koff: 6.30E+4s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Antagonistic activity of the compound against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg .More data for this Ligand-Target Pair
Affinity DataKi: 14nM Koff: 5.60E+3s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 15nM Koff: 1.10E+3s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 15nM Koff: 5.60E+3s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 15nM Koff: 1.30E+3s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 20nM Koff: 1.30E+3s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 26nM Koff: 130s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 32nM Koff: 3.20E+3s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 39nM Koff: 140s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 60nM Koff: 4.40E+3s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 62nM Koff: 240s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 74nM Koff: 280s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 400nM Koff: 210s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 730nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 1.15E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+3nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
Affinity DataKi: 1.55E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.58E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.77E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.81E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.84E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.89E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.93E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.96E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.36E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.41E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair