Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50128671,50343079,50343080,50343081,50343082   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(CHEMBL1771216 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343080(CHEMBL1771215 | N-hydroxy-4-(4-(3-(5-(4-(trifluoro...)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(CHEMBL1771217 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(CHEMBL1771216 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343080(CHEMBL1771215 | N-hydroxy-4-(4-(3-(5-(4-(trifluoro...)
Affinity DataKi:  28nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(CHEMBL1771217 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  44nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(CHEMBL1771216 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataKi:  80nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(CHEMBL1771217 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  110nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(CHEMBL1771216 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataKi:  160nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343080(CHEMBL1771215 | N-hydroxy-4-(4-(3-(5-(4-(trifluoro...)
Affinity DataKi:  170nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(CHEMBL1771216 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataKi:  230nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(CHEMBL1771217 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  240nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343080(CHEMBL1771215 | N-hydroxy-4-(4-(3-(5-(4-(trifluoro...)
Affinity DataKi:  410nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343080(CHEMBL1771215 | N-hydroxy-4-(4-(3-(5-(4-(trifluoro...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(CHEMBL1771217 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(CHEMBL1771217 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(CHEMBL1771217 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343079(CHEMBL1771214 | N-hydroxy-4-(4-(3-(5-(4-methoxyphe...)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(CHEMBL1771216 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(CHEMBL1771216 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343079(CHEMBL1771214 | N-hydroxy-4-(4-(3-(5-(4-methoxyphe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343080(CHEMBL1771215 | N-hydroxy-4-(4-(3-(5-(4-(trifluoro...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(CHEMBL1771217 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343080(CHEMBL1771215 | N-hydroxy-4-(4-(3-(5-(4-(trifluoro...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(CHEMBL1771216 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343080(CHEMBL1771215 | N-hydroxy-4-(4-(3-(5-(4-(trifluoro...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128671(4-(4-Butoxy-benzenesulfonyl)-1-(2-phenoxy-ethyl)-p...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128671(4-(4-Butoxy-benzenesulfonyl)-1-(2-phenoxy-ethyl)-p...)
Affinity DataIC50:  2.90E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128671(4-(4-Butoxy-benzenesulfonyl)-1-(2-phenoxy-ethyl)-p...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343079(CHEMBL1771214 | N-hydroxy-4-(4-(3-(5-(4-methoxyphe...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343079(CHEMBL1771214 | N-hydroxy-4-(4-(3-(5-(4-methoxyphe...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343079(CHEMBL1771214 | N-hydroxy-4-(4-(3-(5-(4-methoxyphe...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343079(CHEMBL1771214 | N-hydroxy-4-(4-(3-(5-(4-methoxyphe...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128671(4-(4-Butoxy-benzenesulfonyl)-1-(2-phenoxy-ethyl)-p...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343079(CHEMBL1771214 | N-hydroxy-4-(4-(3-(5-(4-methoxyphe...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed