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Found 59 Enz. Inhib. hit(s) with Target = '1-deoxy-D-xylulose-5-phosphate synthase'
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496737(CHEMBL3220783)
Affinity DataKi:  960nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50026326(CHEMBL3305928)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496738(CHEMBL3220785)
Affinity DataKi:  5.60E+3nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli O127:H6 (strain E2348/69 / EPEC))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50026326(CHEMBL3305928)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of Escherichia coli DXSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496736(CHEMBL3220784)
Affinity DataKi:  6.70E+3nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli O127:H6 (strain E2348/69 / EPEC))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50026312(CHEMBL3306297)
Affinity DataKi:  6.70E+3nMAssay Description:Inhibition of Escherichia coli DXSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli O127:H6 (strain E2348/69 / EPEC))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50026348(CHEMBL3359030)
Affinity DataKi:  1.04E+4nMAssay Description:Inhibition of Escherichia coli DXSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Haemophilus influenzae (strain 86-028NP))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50026349(KETOCLOMAZONE)
Affinity DataKi:  2.33E+4nMAssay Description:Inhibition of Haemophilus influenzae DXSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496741(CHEMBL3220786)
Affinity DataKi:  2.58E+5nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM108228(1‐nitroso‐2‐naphthol (Substrate ...)
Affinity DataKi:  4.22E+5nM ΔG°:  -20.0kJ/mole IC50:  1.07E+6nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496740(CHEMBL3220788)
Affinity DataKi: >1.00E+6nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496739(CHEMBL3220787)
Affinity DataKi: >1.00E+6nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Arabidopsis thaliana)
Basf-Se

Curated by ChEMBL
LigandPNGBDBM50026349(KETOCLOMAZONE)
Affinity DataIC50:  80nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Haemophilus influenzae (strain 86-028NP))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50026350(CHEMBL3359031)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Haemophilus influenzae DXSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Haemophilus influenzae (strain 86-028NP))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50026351(CHEMBL3359032)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Haemophilus influenzae DXSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264033(3-(4-fluorophenyl)-5-(4-methoxyphenyl)-2-methylpyr...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263972(3-(4-chlorophenyl)-5-(4-methoxyphenyl)-2-methylpyr...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263925(5-benzyl-3-(4-chlorophenyl)-2-(trifluoromethyl)pyr...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264091(2-methyl-3,5-diphenyl-6-propylpyrazolo[1,5-a]pyrim...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264090(2-methyl-5-(naphthalen-2-yl)-3-phenylpyrazolo[1,5-...)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264092(3-(4-chlorophenyl)-2-ethyl-5-(4-methoxyphenyl)pyra...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM58242(3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)-1...)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM51305(3,5-diphenyl-2-(trifluoromethyl)-1H-pyrazolo[1,5-a...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264035(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7(4H...)
Affinity DataIC50:  3.06E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Arabidopsis thaliana)
Basf-Se

Curated by ChEMBL
LigandPNGBDBM50488590(CHEMBL526942 | TCMDC-125235)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Arabidopsis thaliana)
Basf-Se

Curated by ChEMBL
LigandPNGBDBM50488588(CHEMBL2289498)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263971(3-(4-chlorophenyl)-2-methyl-5-phenylpyrazolo[1,5-a...)
Affinity DataIC50:  3.42E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264037(3-(4-chlorophenyl)-5-((4-chlorophenylthio)methyl)-...)
Affinity DataIC50:  4.14E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263970(3,5-bis(4-methoxyphenyl)-2-methylpyrazolo[1,5-a]py...)
Affinity DataIC50:  4.24E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Arabidopsis thaliana)
Basf-Se

Curated by ChEMBL
LigandPNGBDBM50488589(CHEMBL2289496)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264034(3-(4-bromophenyl)-5-(2-methoxyphenyl)-2-methylpyra...)
Affinity DataIC50:  5.35E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264036(3-(4-chlorophenyl)-2-methyl-5-((1-phenyl-1H-tetraz...)
Affinity DataIC50:  5.51E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Arabidopsis thaliana)
Basf-Se

Curated by ChEMBL
LigandPNGBDBM50488595(CHEMBL2289497)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264088(5-((4-chlorophenylthio)methyl)-2-methyl-3-phenylpy...)
Affinity DataIC50:  6.37E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263876(5-benzyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-...)
Affinity DataIC50:  7.11E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263927(CHEMBL491398 | methyl 2-(3-(4-bromophenyl)-7-oxo-2...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263969(3-(4-methoxyphenyl)-2-methyl-5-phenylpyrazolo[1,5-...)
Affinity DataIC50:  9.07E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263929(3-(4-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyr...)
Affinity DataIC50:  9.84E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263817(5-benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50:  1.14E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263344(3,5-Bis-(4-chloro-phenyl)-7-trifluoromethyl-pyrazo...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50264089(3-(4-chlorophenyl)-5-(methoxymethyl)-2-methylpyraz...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM40457(3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(tr...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263928(3-(4-bromophenyl)-5-methyl-2-(trifluoromethyl)pyra...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263873(3-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263874(CHEMBL1608283 | ethyl 2-(5-methyl-7-oxo-3-phenyl-4...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263875(5-(chloromethyl)-3-phenylpyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263872(3-(4-chlorophenyl)-5-(methoxymethyl)pyrazolo[1,5-a...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50263345(3-(3-Bromo-phenyl)-5,7-diphenyl-pyrazolo[1,5-a]pyr...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50065935(CHEMBL98797 | NOB | Nitrosobenzene (Substrate 1) |...)
Affinity DataIC50:  2.08E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli K-12 (Enterobacteria))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM108226(1‐methyl‐2‐nitrosobenzene (Subst...)
Affinity DataIC50:  2.91E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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