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Found 573 Enz. Inhib. hit(s) with Target = 'Capsid protein'
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50586563(CHEMBL4741463)
Affinity DataIC50:  12nMAssay Description:Modulation of capsid assembly in HBV assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50366817(Epivir)
Affinity DataIC50: <100nMAssay Description:Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM supplemented wi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50278715(BAY-414109 | CHEMBL605300)
Affinity DataIC50:  430nMAssay Description:Inhibition of HBV C150-Bodipy FL N-(2-aminoethyl) maleimide labeled capsid assessed as reduction in NaCl-induced capsid assembly preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50513194(CHEMBL4555299)
Affinity DataIC50:  710nMAssay Description:Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM supplemented wi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50278717(CHEMBL4163583)
Affinity DataIC50:  800nMAssay Description:Inhibition of HBV C150-Bodipy FL N-(2-aminoethyl) maleimide labeled capsid assessed as reduction in NaCl-induced capsid assembly preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50513194(CHEMBL4555299)
Affinity DataIC50:  840nMAssay Description:Inhibition of capsid protein in lamivudine/entecavir-resistant Hepatitis B virus harboring rtL180M/rtM204V/rt184L mutant infected in human HepG2.2.15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50278716(CHEMBL4101961)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HBV C150-Bodipy FL N-(2-aminoethyl) maleimide labeled capsid assessed as reduction in NaCl-induced capsid assembly preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50513195(CHEMBL4454178)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM supplemented wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50501710(CHEMBL4084221)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of HBV capsid assembly infected in human HepG2(2.2.15) cells assessed as inhibition of intracellular viral DNA level after 8 days by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50513195(CHEMBL4454178)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of capsid protein in lamivudine/entecavir-resistant Hepatitis B virus harboring rtL180M/rtM204V/rt184L mutant infected in human HepG2.2.15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50513199(CHEMBL4525697)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM supplemented wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50513197(CHEMBL4525261)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM supplemented wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50586562(CHEMBL4781128)
Affinity DataIC50:  2.80E+3nMAssay Description:Modulation of capsid assembly in HBV assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50513196(CHEMBL4555874)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM supplemented wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50513198(CHEMBL4536243)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM supplemented wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50366817(Epivir)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of capsid protein in lamivudine/entecavir-resistant Hepatitis B virus harboring rtL180M/rtM204V/rt184L mutant infected in human HepG2.2.15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50371195(CHEMBL395636)
Affinity DataKd:  7.94E+4nMAssay Description:Binding affinity to HBcAgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50371196(CHEMBL236749)
Affinity DataKd:  1.85E+4nMAssay Description:Binding affinity to HBcAgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324403(US10189835, Compound 434)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324405(US10189835, Compound 561)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324406(US10189835, Compound 587)
Affinity DataEC50: <1.00E+3nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324408(US10189835, Compound 599)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324409(US10189835, Compound 795)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324410(US10189835, Compound 796)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324411(US10189835, Compound 798)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324412(US10189835, Compound 800)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324413(US10189835, Compound 803)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324415(US10189835, Compound 805)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324416(US10189835, Compound 594)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324417(US10189835, Compound 595)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324418(US10189835, Compound 600)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324419(US10189835, Compound 695)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324421(US10189835, Compound 697)
Affinity DataEC50: <1.00E+3nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324422(US10189835, Compound 698)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324423(US10189835, Compound 699)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324424(US10189835, Compound 828)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324424(US10189835, Compound 828)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324425(US10189835, Compound 910)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324426(US10189835, Compound 912)
Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent
LigandPNGBDBM324427(US10189835, Compound 937)
Affinity DataEC50: <100nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  12nMAssay Description:Inhibition of reverse transcriptase M204I/S202G double mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50001103((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
Affinity DataEC50:  83nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50278715(BAY-414109 | CHEMBL605300)
Affinity DataEC50:  48nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50247732(CHEMBL4082519)
Affinity DataEC50: >1.64E+4nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50247801(CHEMBL4070728)
Affinity DataEC50:  42nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50247811(CHEMBL4078766)
Affinity DataEC50:  3nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50450781(CHEMBL4205737)
Affinity DataEC50:  26nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50450782(CHEMBL4209011)
Affinity DataEC50:  100nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50450783(CHEMBL4208472)
Affinity DataEC50:  3.50E+3nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL
LigandPNGBDBM50450784(CHEMBL4217281)
Affinity DataEC50:  200nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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