Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with Target = 'Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH1/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2'
LigandPNGBDBM50287072(CHEMBL4159112 | US10759787, Example 12 | US1105981...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287050(CHEMBL4161265)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287052(CHEMBL4165937)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287284(CHEMBL4160111)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287068(CHEMBL4172576 | US10759787, Example 30 | US1105981...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287071(CHEMBL4164687 | US10759787, Example 29 | US1105981...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287125(CHEMBL4170327 | US10759787, Example 19 | US1105981...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287049(CHEMBL4162316)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287283(CHEMBL4177454)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287048(CHEMBL4162499 | US10759787, Example 9 | US11059811...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287054(CHEMBL4174176)
Affinity DataIC50:  4nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM172038(US10155002, Compound 44 | US10647700, Compound EPZ...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287277(CHEMBL4170753 | US10759787, Example 18 | US1105981...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287058(CHEMBL4169191)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287051(CHEMBL4169368)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287276(CHEMBL4162406)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287056(CHEMBL4169598 | US10759787, Example 20 | US1105981...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287306(CHEMBL4167587)
Affinity DataIC50:  6nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287119(CHEMBL4169762)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287053(CHEMBL4161444 | US10759787, Example 1 | US11059811...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287047(CHEMBL4176373)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287307(CHEMBL4176554 | US10759787, Example 6 | US11059811...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149895(CHEMBL3770000)
Affinity DataIC50:  20nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50:  50nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
LigandPNGBDBM50287055(CHEMBL4172992)
Affinity DataIC50:  331nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287057(CHEMBL4165760)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed