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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [2420-2989,P2914A,R2963Q]'
TargetGenome polyprotein [2420-2989,P2914A,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,P2914A,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair