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Found 467 Enz. Inhib. hit(s) with Target = 'Histone deacetylase (HDAC1 and HDAC2)'
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221964(CHEMBL114184)
Affinity DataIC50:  0.0200nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221943(CHEMBL432618)
Affinity DataIC50:  0.0620nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221809(CHEMBL321689)
Affinity DataIC50:  0.0820nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221786(CHEMBL432243)
Affinity DataIC50:  0.109nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221965(CHEMBL113303)
Affinity DataIC50:  0.110nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221785(CHEMBL112984)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27188(triazole-linked clarithromycin-based compound, 24d)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of HDAC1/2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222318(CHEMBL123626)
Affinity DataIC50:  2.10nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222327(CHEMBL124282)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222343(CHEMBL339720)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218532(CHEMBL112148)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220817(CHEMBL57792)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221925(CHEMBL113033)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220805(CHEMBL294194)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220804(CHEMBL301223)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220802(CHEMBL54409)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221807(CHEMBL115049)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM25152(CHEMBL112446 | N-methyl-2-oxo-N'-(3-phenylphenyl)n...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27187(triazole-linked clarithromycin-based compound, 24c)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of HDAC1/2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221814(CHEMBL113034)
Affinity DataIC50:  4.30nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222339(CHEMBL340885)
Affinity DataIC50:  4.30nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222342(CHEMBL435415)
Affinity DataIC50:  4.30nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222345(CHEMBL123905)
Affinity DataIC50:  4.40nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221938(CHEMBL321253)
Affinity DataIC50:  4.90nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221988(CHEMBL113566)
Affinity DataIC50: >5nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220819(CHEMBL58487)
Affinity DataIC50:  5.40nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222363(CHEMBL125042)
Affinity DataIC50:  5.80nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220807(CHEMBL294447)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220806(CHEMBL293812)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222341(CHEMBL124650)
Affinity DataIC50:  6.80nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222319(CHEMBL340835)
Affinity DataIC50:  8.5nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222011(CHEMBL324429)
Affinity DataIC50:  9.10nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218242(CHEMBL115812)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221941(CHEMBL420300)
Affinity DataIC50:  9.40nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221810(CHEMBL111898)
Affinity DataIC50:  9.5nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222334(CHEMBL127846)
Affinity DataIC50:  9.80nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220822(CHEMBL56214)
Affinity DataIC50:  9.90nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells.More data for this Ligand-Target Pair
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  11nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cell nuclear extract preincubated for 20 mins followed by addition of HDAC green as substrate measured after ...More data for this Ligand-Target Pair
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50511602(CHEMBL4463372)
Affinity DataIC50:  11nMAssay Description:Inhibition of HDAC1/2 in human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (trif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221940(CHEMBL333150)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against mixture of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) from nuclear extraction of K562 erythroleukemi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222365(CHEMBL340113)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222323(CHEMBL126274)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220824(CHEMBL56782)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220793(CHEMBL54408)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222344(CHEMBL339796)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220810(CHEMBL57226)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220795(CHEMBL57106)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity was tested against histone deacetylase (HDAC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50222338(CHEMBL127184)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50498393(CHEMBL3594331)
Affinity DataIC50:  13nMAssay Description:Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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