Found 24 Enz. Inhib. hit(s) with Target = 'Adenosine 5'-monophosphoramidase HINT1' TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 3.40E+4nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 1.03E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 1.39E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 4.00E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 4.57E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 7.15E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells using TrpAMP as substrate measured for 2 to 30 mins by fluorescenc...More data for this Ligand-Target Pair
3D Structure (crystal)TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells using TrpAMP as substrate measured for 2 to 30 mins by fluorescenc...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 6.70E+4nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 3.65E+3nMAssay Description:Binding affinity to recombinant human HINT1 by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 320nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 810nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 920nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 920nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 2.90E+3nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 2.90E+3nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 3.65E+3nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKd: 6.00E+4nMAssay Description:Binding affinity to mouse HINT1 by NMR analysisMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKd: 1.20E+6nMAssay Description:Binding affinity to mouse HINT1 by HSQC spectra assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKd: 1.10E+6nMAssay Description:Binding affinity to mouse HINT1 by fluorescence quenching assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKd: 6.70E+4nMAssay Description:Binding affinity to mouse HINT1 by fluorescence quenching assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 810nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
