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Found 977 Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 2'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform); Range is 6-10 nMMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  7nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity of the compound against IMPDH II with respect to IMP and NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  10nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  10nMAssay Description:Inhibition of human IMPDH 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  10nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494944(CHEMBL3098163)
Affinity DataKi:  13nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338536(CHEMBL1683637 | [({[(2S,3R,4S,5S)-5-(6-amino-2-eth...)
Affinity DataKi:  14nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19263(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 33...)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494940(CHEMBL3098189)
Affinity DataKi:  14nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494943(CHEMBL3098188)
Affinity DataKi:  15nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369348(CHEMBL606286)
Affinity DataKi:  21nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494941(CHEMBL3098187)
Affinity DataKi:  24nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338539(CHEMBL1683640 | Mycophenolic 2-ethyladenosin-5'-yl...)
Affinity DataKi:  24nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50369348(CHEMBL606286)
Affinity DataKi:  26nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19257(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 27...)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228085(CHEMBL238461 | N-hydroxy-6-(4-hydroxy-6-methoxy-7-...)
Affinity DataKi:  30nMAssay Description:Inhibition of human IMPDH 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338537(CHEMBL1683638 | Tiazofurin-5'-yl-2-ethyladenosin-5...)
Affinity DataKi:  30nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322457(6-((E)-4-(((1-(50-Deoxy-adenosin-50-yl)-1H-1,2,3-t...)
Affinity DataKi:  34nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338553(6-(-4-((1-(((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl...)
Affinity DataKi:  34nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494911(CHEMBL3098190)
Affinity DataKi:  37nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192467(CHEMBL384114 | P1-[7-hydroxy-6-(ethyl-2-yl)-5-meth...)
Affinity DataKi:  37nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338541(((((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dih...)
Affinity DataKi:  37nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19267(CHEMBL392204 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19267(CHEMBL392204 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  38nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338538(CHEMBL1683639 | {[(2S,3R,4S,5S)-5-(6-Amino-2-ethyl...)
Affinity DataKi:  38nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338550(CHEMBL1683752 | Mycophenolic ethylenephosphonate-5...)
Affinity DataKi:  39nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19267(CHEMBL392204 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  40nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494942(CHEMBL3098169)
Affinity DataKi:  40nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338552(6-(-4-(4-((((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl...)
Affinity DataKi:  44nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494912(CHEMBL3098192)
Affinity DataKi:  44nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322459(6-((E)-4-(4-(Adenosin-50-yl)methyl-1H-1,2,3-triazo...)
Affinity DataKi:  44nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19261(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 31...)
Affinity DataKi:  49nM ΔG°:  -41.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494906(CHEMBL3098191)
Affinity DataKi:  56nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192469(CHEMBL215311 | P1-(adenosin-5'-yl)methylenephospho...)
Affinity DataKi:  60nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338540(((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Affinity DataKi:  60nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494909(CHEMBL3098183)
Affinity DataKi:  70nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338543(CHEMBL1683745 | Mycophenolic 2-ethyladenosin-5'-yl...)
Affinity DataKi:  73nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338547(CHEMBL1683749 | Mycophenolic(adenosine-5'-N-acetam...)
Affinity DataKi:  83nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19255(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 25...)
Affinity DataKi:  84nM ΔG°:  -40.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494917(CHEMBL3098182)
Affinity DataKi:  84nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338542(CHEMBL1683744 | Mycophenolic adenosin-5'-yl-ethyle...)
Affinity DataKi:  84nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494929(CHEMBL3098184)
Affinity DataKi:  88nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494932(CHEMBL3098172)
Affinity DataKi:  94nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19262(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 32...)
Affinity DataKi:  94nM ΔG°:  -40.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19253(CHEMBL394276 | NSC 358285 | Tiazofurin Adenine Din...)
Affinity DataKi:  100nMAssay Description:Inhibition of human IMPDH 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50494939(CHEMBL3098180)
Affinity DataKi:  102nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19266(CHEMBL410745 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  108nM ΔG°:  -39.8kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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