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Found 17 Enz. Inhib. hit(s) with Target = 'Peptidoglycan D,D-transpeptidase MrdA'
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512952(CHEMBL4560540)
Affinity DataIC50:  10nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512949(CHEMBL4470489)
Affinity DataIC50:  17nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512948(CHEMBL4476279)
Affinity DataIC50:  25nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50213266(CHEBI:471744 | Imipenem | MK-0787)
Affinity DataIC50:  33.4nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213266(CHEBI:471744 | Imipenem | MK-0787)
Affinity DataIC50:  334nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50103601(CHEBI:29007 | Ceftriaxone)
Affinity DataIC50:  360nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50378857(CEFTOBIPROLE | Zeftera | Zevtera)
Affinity DataIC50:  374nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512953(CHEMBL4515223)
Affinity DataIC50:  570nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512951(Avibactam sodium | CHEBI:85982 | Nxl-104)
Affinity DataIC50:  590nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50350470(CEFEPIME | Maxipime)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50378857(CEFTOBIPROLE | Zeftera | Zevtera)
Affinity DataIC50:  5.61E+3nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50:  7.31E+3nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50350470(CEFEPIME | Maxipime)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50240480((2S,3S)-3-({(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-...)
Affinity DataIC50: >1.83E+4nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50240480((2S,3S)-3-({(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-...)
Affinity DataIC50:  3.67E+4nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50: >5.85E+4nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512950(CHEMBL4545278)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed