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Found 30 Enz. Inhib. hit(s) with Target = 'Beta-adrenergic receptor kinase 2'
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525308(US11173144, Compound 72)
Affinity DataIC50:  0.00900nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525317(US11173144, Compound 90)
Affinity DataIC50:  0.0190nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525320(US11173144, Compound 52)
Affinity DataIC50:  0.0240nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525316(US11173144, Compound 69)
Affinity DataIC50:  0.0480nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525318(US11173144, Compound 75)
Affinity DataIC50:  0.0650nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525322(US11173144, Compound 86)
Affinity DataIC50:  0.144nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525319(US11173144, Compound 87)
Affinity DataIC50:  0.230nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525321(US11173144, Compound 55)
Affinity DataIC50:  0.380nMAssay Description:ADRB2 IC50 from binding assay(nM), Determined using the Tag-lite Adrenoceptor Beta2 receptor ligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257340(CHEMBL4072828)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257328(CHEMBL4082775)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257365(CHEMBL4083276)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257344(CHEMBL4065690)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257350(CHEMBL1738877)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257350(CHEMBL1738877)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of GRK3 (unknown origin)More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50257351(CHEMBL4095595)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK3 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  47nMAssay Description:Inhibition of GRK3-mediated bovine tubulin phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  850nMAssay Description:Inhibition of human GRK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  861nMAssay Description:Inhibition of human GRK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50191311(CHEMBL3950887)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50191313(CHEMBL3931500)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50566946(CHEMBL4854871)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50566947(CHEMBL4847703)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50566949(CHEMBL4877302)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human GRK3 using casein as substrate after 40 mins in presence of [gamma-33ATP] by radiometric scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50191319(CHEMBL3942164)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50191326(CHEMBL3953837)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50191312(CHEMBL3900757)
Affinity DataIC50:  3.04E+4nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50191310(CHEMBL3971763)
Affinity DataIC50:  5.55E+4nMAssay Description:Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed