Compile Data Set for Download or QSAR
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Found 10 Enz. Inhib. hit(s) with Target = 'Neutral ceramidase'
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569050(CHEMBL4848172)
Affinity DataKi:  800nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569051(CHEMBL4865548)
Affinity DataKi:  2.00E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569048(CHEMBL4861323)
Affinity DataKi:  3.60E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569049(CHEMBL4878103)
Affinity DataKi:  5.40E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569052(CHEMBL4866400)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human ASAH2 using RBM14C24 fluorogenic substrate measured at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569052(CHEMBL4866400)
Affinity DataIC50:  366nMAssay Description:Inhibition of human ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 fluorogenic substrate measured at pH 7.5 by fluorescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50392471(CHEMBL2152040)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of recombinant human nCDase expressed in Sf9 cells using fluorescently-labeled acyl-NBD-C12-ceramide as substrate after 2 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50392472(CHEMBL408217)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of recombinant human nCDase expressed in Sf9 cells using fluorescently-labeled acyl-NBD-C12-ceramide as substrate after 2 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50392472(CHEMBL408217)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human recombinant neutral ceramidase using Acyl-NBD-C12-cer as substrate after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50428951(CHEMBL2333179)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human recombinant neutral ceramidase using Acyl-NBD-C12-cer as substrate after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed