Compile Data Set for Download or QSAR
maximum 50k data
Found 327 Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor'
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105938(4-{N'-[1-(3,4-Dimethyl-phenyl)-3-ethoxy-5-oxo-1,5-...)
Affinity DataEC50:  600nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105936(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-phenyl-1,5-dihyd...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105937(3-Hydroxy-4-(10-hydroxy-phenanthren-9-ylazo)-napht...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105939(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-o-tolyl-1,5-dihy...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105940(4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-1,5-dihydro-p...)
Affinity DataEC50:  100nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105942(4-{N'-[1-(3-tert-Butyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  70nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105944(3-Hydroxy-4-(2-hydroxy-5-methyl-phenylazo)-naphtha...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105941(4-(2,3-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105943(4-[N'-(1-Benzyl-3-methyl-5-oxo-1,5-dihydro-pyrazol...)
Affinity DataEC50: >3.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105947(3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(3-trifluorometh...)
Affinity DataEC50:  40nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105946(4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-3-phenyl-1,5-...)
Affinity DataEC50:  900nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105948(4-{N'-[1-(3-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105949(4-(2,4-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105951(4-(2,6-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105952(4-{N'-[1-(4-Fluoro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50:  500nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105945(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-p-tolyl-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105956(3-Hydroxy-4-(2-hydroxy-4-sulfo-naphthalen-1-ylazo)...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105953(4-(2,7-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105955(3-Hydroxy-4-{N'-[3-methyl-1-(2-nitro-phenyl)-5-oxo...)
Affinity DataEC50:  8.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105954(1-(4-tert-Butyl-phenyl)-4-[(2-hydroxy-4-sulfo-naph...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105959(3-Hydroxy-4-{N'-[3-methyl-1-(4-nitro-phenyl)-5-oxo...)
Affinity DataEC50:  400nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105958(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-p-tolyl-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105950(4-{N'-[1-(3,4-Dichloro-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105957(4-{N'-[3-Amino-1-(4-tert-butyl-phenyl)-5-oxo-1,5-d...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105962(3-Hydroxy-4-{N'-[1-(4-isopropyl-phenyl)-3-methyl-5...)
Affinity DataEC50:  70nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105960(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-m-tolyl-1,5-dihy...)
Affinity DataEC50:  700nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105961(3-Hydroxy-4-(2-hydroxy-7-methoxy-naphthalen-1-ylaz...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105964(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-pyridin-2-yl-1,5...)
Affinity DataEC50:  7.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105967(3-Hydroxy-4-{N'-[1-(4-iodo-phenyl)-3-methyl-5-oxo-...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105966(3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(4-trifluorometh...)
Affinity DataEC50:  100nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105968(4-{N'-[1-(4-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105969(4-{N'-[1-(4-Benzyloxy-phenyl)-3-methyl-5-oxo-1,5-d...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105972(3-Hydroxy-4-{N'-[3-methyl-1-(3-nitro-phenyl)-5-oxo...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105973(4-{N'-[3-tert-Butyl-1-(3,4-dimethyl-phenyl)-5-oxo-...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105970(4-{N'-[1-(4-tert-Butyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  20nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105971(4-{N'-[1-(2-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50: >3.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105976(3-Hydroxy-4-(1-hydroxy-naphthalen-2-ylazo)-naphtha...)
Affinity DataEC50:  70nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105974(3-Hydroxy-4-(4-hydroxy-2-methoxy-naphthalen-1-ylaz...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105975(3-Hydroxy-4-{N'-[1-(4-methanesulfonyl-phenyl)-3-me...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105977(3-Hydroxy-4-(2-hydroxy-naphthalen-1-ylazo)-naphtha...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105978(4-{N'-[1-(3-Ethylsulfamoyl-phenyl)-3-methyl-5-oxo-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105979(1-(4-tert-Butyl-phenyl)-4-[(2-hydroxy-4-sulfo-naph...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105980(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-phenyl-1,5-dihyd...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105963(4-{N'-[1-(3,4-Dimethyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  40nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105965(4-{N'-[1-(3,4-Dimethyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179469(5-((2-(6-(4-tert-butylphenyl)pyridin-2-yl)-1H-benz...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179470(5-((2-(6-(3,4-dichlorophenyl)pyridin-2-yl)-1H-benz...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179471(5-[1-[2-(4'-tert-Butyl-2-hydroxy-biphenyl-3-yl)-1H...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179473(2-((2-(6-(4-tert-butylphenyl)pyridin-2-yl)-1H-benz...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179472(5-((2-(4-(3,4-dimethylphenyl)thiophen-2-yl)-1H-ben...)
Affinity DataEC50:  780nMAssay Description:Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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