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Found 30 Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase CDC14A'
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425807(CHEMBL2316902)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50:  7.20E+3nMpH: 7.0Assay Description:Inhibition of CDC14A (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  1.60E+4nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425808(CHEMBL2316906)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50308158(3-(1-(3-(Biphenyl-4-ylamino)-3-oxopropyl)-1H-1,2,3...)
Affinity DataIC50: >5.00E+4nMpH: 7.0Assay Description:Inhibition of Cdc14A expressed in Escherichia coli assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH 7 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50343147(CHEMBL1773180 | N1-(furan-2-ylmethyl)-N2-(1-(4-(4-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112357(CHEMBL3609375)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112358(CHEMBL3609374)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50343142(CHEMBL1773168 | N-(4-butylphenyl)-2-oxo-1,2-dihydr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558461(CHEMBL4760367)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558485(CHEMBL4800195)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558483(CHEMBL4778085)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558484(CHEMBL4748824)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558486(CHEMBL4797766)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558487(CHEMBL4786243)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558482(CHEMBL4742123)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558481(CHEMBL4783639)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50420258(CEFSULODIN)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed