BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 34475 CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1Cc1ccccc1 |r| InChI=1S/C33H35N7O/c1-33(2,34)32(41)37-29(18-24-20-36-28-15-9-7-13-26(24)28)31-39-38-30(40(31)21-22-10-4-3-5-11-22)17-16-23-19-35-27-14-8-6-12-25(23)27/h3-15,19-20,29,35-36H,16-18,21,34H2,1-2H3,(H,37,41) BLVAQCTVXRMXDP-UHFFFAOYSA-N 19293 2-amino-N-[(1R)-1-{4-benzyl-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]-2-methylpropanamide::CHEMBL374073::(R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-2-amino-2-methylpropanamide::Trisubstituted 1,2,4-Triazole, 1 Growth hormone secretagogue receptor type 1 Homo sapiens 15 64 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19293 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19293&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113691 46519321 CHEMBL374073 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34476 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1 |r| InChI=1S/C34H37N7O2/c1-34(2,35)33(42)38-30(18-24-20-37-29-11-7-5-9-27(24)29)32-40-39-31(41(32)21-22-12-15-25(43-3)16-13-22)17-14-23-19-36-28-10-6-4-8-26(23)28/h4-13,15-16,19-20,30,36-37H,14,17-18,21,35H2,1-3H3,(H,38,42) RJPIWPXFPIJADI-UHFFFAOYSA-N 19294 CHEMBL374643::2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]-2-methylpropanamide::Trisubstituted 1,2,4-Triazole, 2 Growth hormone secretagogue receptor type 1 Homo sapiens 6 4 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19294 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19294&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113695 46519322 CHEMBL374643 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34477 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 |r| InChI=1S/C32H33N7O2/c1-41-24-13-10-21(11-14-24)20-39-30(15-12-22-18-34-27-8-4-2-6-25(22)27)37-38-32(39)29(36-31(40)17-33)16-23-19-35-28-9-5-3-7-26(23)28/h2-11,13-14,18-19,29,34-35H,12,15-17,20,33H2,1H3,(H,36,40) CMBOQDMBRZABGG-UHFFFAOYSA-N 19295 2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]acetamide::Trisubstituted 1,2,4-Triazole, 3 Growth hormone secretagogue receptor type 1 Homo sapiens 138 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19295 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19295&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648231 46519323 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34478 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 |r| InChI=1S/C30H32N6O2/c1-38-24-14-11-22(12-15-24)20-36-28(16-13-21-7-3-2-4-8-21)34-35-30(36)27(33-29(37)18-31)17-23-19-32-26-10-6-5-9-25(23)26/h2-12,14-15,19,27,32H,13,16-18,20,31H2,1H3,(H,33,37) OZSZELOMMMKWTM-UHFFFAOYSA-N 19296 JMV2959::2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]acetamide::Trisubstituted 1,2,4-Triazole, 4 Growth hormone secretagogue receptor type 1 Homo sapiens 32 19 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19296 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19296&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114404 46519324 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34479 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)c(OC)c1 |r| InChI=1S/C33H35N7O3/c1-42-24-13-11-22(30(16-24)43-2)20-40-31(14-12-21-18-35-27-9-5-3-7-25(21)27)38-39-33(40)29(37-32(41)17-34)15-23-19-36-28-10-6-4-8-26(23)28/h3-11,13,16,18-19,29,35-36H,12,14-15,17,20,34H2,1-2H3,(H,37,41) WWQWKRWAIHYINO-UHFFFAOYSA-N 19297 2-amino-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]acetamide::Trisubstituted 1,2,4-Triazole, 5 Growth hormone secretagogue receptor type 1 Homo sapiens 38 27 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19297 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19297&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113002 46519325 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34480 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)c(OC)c1 |r| InChI=1S/C31H34N6O3/c1-39-24-14-13-22(28(17-24)40-2)20-37-29(15-12-21-8-4-3-5-9-21)35-36-31(37)27(34-30(38)18-32)16-23-19-33-26-11-7-6-10-25(23)26/h3-11,13-14,17,19,27,33H,12,15-16,18,20,32H2,1-2H3,(H,34,38) UBXHWKKKGGECRZ-UHFFFAOYSA-N 19298 2-amino-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]acetamide::Trisubstituted 1,2,4-Triazole, 6 Growth hormone secretagogue receptor type 1 Homo sapiens 154 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19298 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19298&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113122 46519326 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34481 CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 |r| InChI=1S/C31H34N6O/c1-2-22-12-14-24(15-13-22)21-37-29(17-16-23-8-4-3-5-9-23)35-36-31(37)28(34-30(38)19-32)18-25-20-33-27-11-7-6-10-26(25)27/h3-15,20,28,33H,2,16-19,21,32H2,1H3,(H,34,38) FLMXGJYIFYQORQ-UHFFFAOYSA-N 19299 2-amino-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]acetamide::Trisubstituted 1,2,4-Triazole, 7 Growth hormone secretagogue receptor type 1 Homo sapiens 759 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19299 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19299&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648232 46519327 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34482 NCC(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1 |r| InChI=1S/C28H28N6O/c29-18-27(35)31-25(17-21-19-30-24-14-8-7-13-23(21)24)28-33-32-26(16-15-20-9-3-1-4-10-20)34(28)22-11-5-2-6-12-22/h1-14,19,25,30H,15-18,29H2,(H,31,35) MNJBFWNIEUCCFS-UHFFFAOYSA-N 19300 2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-[4-phenyl-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]ethyl]acetamide::Trisubstituted 1,2,4-Triazole, 8 Growth hormone secretagogue receptor type 1 Homo sapiens >1000 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19300 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19300&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648233 46519328 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34483 COc1ccc(c(OC)c1)-n1c(CCc2ccccc2)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CN |r,wU:23.38,(4.36,-2.45,;2.85,-2.19,;2.31,-.75,;.8,-.48,;.27,.96,;1.25,2.14,;2.77,1.88,;3.76,3.06,;5.3,3.06,;3.3,.44,;.85,3.63,;2.12,4.51,;3.57,4,;4.74,5.01,;4.74,6.55,;3.4,7.32,;3.4,8.86,;4.74,9.63,;6.07,8.86,;6.07,7.32,;1.67,5.98,;.13,6.02,;-.37,4.56,;-1.71,3.79,;-2.48,2.46,;-2.48,.92,;-1.01,.45,;-1.01,-1.09,;-2.47,-1.57,;-3.1,-2.98,;-4.63,-3.15,;-5.53,-1.9,;-4.91,-.49,;-3.38,-.33,;-3.04,4.56,;-4.38,3.79,;-4.38,2.25,;-5.71,4.56,;-7.04,3.79,)| InChI=1S/C30H32N6O3/c1-38-22-13-14-26(27(17-22)39-2)36-28(15-12-20-8-4-3-5-9-20)34-35-30(36)25(33-29(37)18-31)16-21-19-32-24-11-7-6-10-23(21)24/h3-11,13-14,17,19,25,32H,12,15-16,18,31H2,1-2H3,(H,33,37) MSFIVLSDUGNPCO-UHFFFAOYSA-N 19301 2-amino-N-[(1R)-1-[4-(2,4-dimethoxyphenyl)-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]acetamide::Trisubstituted 1,2,4-Triazole, 9 Growth hormone secretagogue receptor type 1 Homo sapiens >1000 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19301 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19301&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648234 46519329 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34484 CCc1ccc(cc1)-n1c(CCc2c[nH]c3ccccc23)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CN |r| InChI=1S/C32H33N7O/c1-2-21-11-14-24(15-12-21)39-30(16-13-22-19-34-27-9-5-3-7-25(22)27)37-38-32(39)29(36-31(40)18-33)17-23-20-35-28-10-6-4-8-26(23)28/h3-12,14-15,19-20,29,34-35H,2,13,16-18,33H2,1H3,(H,36,40) ZKRKDYYBSBSWFU-UHFFFAOYSA-N 19302 2-amino-N-[(1R)-1-[4-(4-ethylphenyl)-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]acetamide::Trisubstituted 1,2,4-Triazole, 10 Growth hormone secretagogue receptor type 1 Homo sapiens >1000 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19302 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19302&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648235 46519330 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34485 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NCCN)c(OC)c1 |r| InChI=1S/C31H36N6O2/c1-38-25-14-13-23(29(19-25)39-2)21-37-30(15-12-22-8-4-3-5-9-22)35-36-31(37)28(33-17-16-32)18-24-20-34-27-11-7-6-10-26(24)27/h3-11,13-14,19-20,28,33-34H,12,15-18,21,32H2,1-2H3 RWMLTVKEJBMKMC-UHFFFAOYSA-N 19303 (2-aminoethyl)[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]amine::Trisubstituted 1,2,4-Triazole, 11 Growth hormone secretagogue receptor type 1 Homo sapiens 190 279 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19303 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19303&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648236 46519331 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34486 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)N)cc1 |r| InChI=1S/C31H34N6O2/c1-21(32)31(38)34-28(18-24-19-33-27-11-7-6-10-26(24)27)30-36-35-29(17-14-22-8-4-3-5-9-22)37(30)20-23-12-15-25(39-2)16-13-23/h3-13,15-16,19,21,28,33H,14,17-18,20,32H2,1-2H3,(H,34,38) BRWMPFXAMGDTEZ-UHFFFAOYSA-N 19304 (S)-N-((R)-1-(4-(4-Methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-2-aminopropanamide::(2S)-2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]propanamide::Trisubstituted 1,2,4-Triazole, 12 Growth hormone secretagogue receptor type 1 Homo sapiens 113 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19304 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19304&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648237 46519332 C03803 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34487 CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)N)cc1 |r| InChI=1S/C32H36N6O/c1-3-23-13-15-25(16-14-23)21-38-30(18-17-24-9-5-4-6-10-24)36-37-31(38)29(35-32(39)22(2)33)19-26-20-34-28-12-8-7-11-27(26)28/h4-16,20,22,29,34H,3,17-19,21,33H2,1-2H3,(H,35,39) VLKCIZDYSQANPO-UHFFFAOYSA-N 19305 (2S)-2-amino-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]propanamide::Trisubstituted 1,2,4-Triazole, 13 Growth hormone secretagogue receptor type 1 Homo sapiens 275 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19305 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19305&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648238 46519333 C03803 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34488 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CCN)cc1 |r| InChI=1S/C31H34N6O2/c1-39-25-14-11-23(12-15-25)21-37-29(16-13-22-7-3-2-4-8-22)35-36-31(37)28(34-30(38)17-18-32)19-24-20-33-27-10-6-5-9-26(24)27/h2-12,14-15,20,28,33H,13,16-19,21,32H2,1H3,(H,34,38) MVYVXOCUMDTQNJ-UHFFFAOYSA-N 19306 3-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]propanamide::(R)-N-(1-(4-(4-Methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-3-aminopropanamide::Trisubstituted 1,2,4-Triazole, 14 Growth hormone secretagogue receptor type 1 Homo sapiens 59 256 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19306 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19306&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114515 46519334 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34489 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](N)Cc2ccccc2)cc1 |r| InChI=1S/C37H38N6O2/c1-45-30-19-16-28(17-20-30)25-43-35(21-18-26-10-4-2-5-11-26)41-42-36(43)34(23-29-24-39-33-15-9-8-14-31(29)33)40-37(44)32(38)22-27-12-6-3-7-13-27/h2-17,19-20,24,32,34,39H,18,21-23,25,38H2,1H3,(H,40,44) MCDRDYFDQCMLIS-UHFFFAOYSA-N 19307 (2S)-2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]-3-phenylpropanamide::Trisubstituted 1,2,4-Triazole, 15 Growth hormone secretagogue receptor type 1 Homo sapiens 175 24 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19307 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19307&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648239 46519335 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34490 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)cc1 |r| InChI=1S/C35H37N7O2/c1-44-26-15-12-23(13-16-26)22-42-33(17-14-24-20-37-29-9-4-2-7-27(24)29)40-41-34(42)32(39-35(43)31-11-6-18-36-31)19-25-21-38-30-10-5-3-8-28(25)30/h2-5,7-10,12-13,15-16,20-21,31-32,36-38H,6,11,14,17-19,22H2,1H3,(H,39,43) DSKXYHYADVMGDR-UHFFFAOYSA-N 19308 (2S)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]pyrrolidine-2-carboxamide::JMV3030::Trisubstituted 1,2,4-Triazole, 16 Growth hormone secretagogue receptor type 1 Homo sapiens 9 6 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19308 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19308&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113371 46519336 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34491 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCN2)cc1 |r| InChI=1S/C35H37N7O2/c1-44-26-15-12-23(13-16-26)22-42-33(17-14-24-20-37-29-9-4-2-7-27(24)29)40-41-34(42)32(39-35(43)31-11-6-18-36-31)19-25-21-38-30-10-5-3-8-28(25)30/h2-5,7-10,12-13,15-16,20-21,31-32,36-38H,6,11,14,17-19,22H2,1H3,(H,39,43) DSKXYHYADVMGDR-UHFFFAOYSA-N 19309 (2R)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]pyrrolidine-2-carboxamide::JMV3031::Trisubstituted 1,2,4-Triazole, 17 Growth hormone secretagogue receptor type 1 Homo sapiens 28 7 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19309 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19309&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113372 46519337 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34492 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)cc1 |r| InChI=1S/C33H36N6O2/c1-41-26-16-13-24(14-17-26)22-39-31(18-15-23-8-3-2-4-9-23)37-38-32(39)30(36-33(40)29-12-7-19-34-29)20-25-21-35-28-11-6-5-10-27(25)28/h2-6,8-11,13-14,16-17,21,29-30,34-35H,7,12,15,18-20,22H2,1H3,(H,36,40) GYSPFGJFPWKCMM-UHFFFAOYSA-N 19310 (2S)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]pyrrolidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 18 Growth hormone secretagogue receptor type 1 Homo sapiens 9.5 13 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19310 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19310&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114293 46519338 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34493 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCN2)cc1 |r| InChI=1S/C33H36N6O2/c1-41-26-16-13-24(14-17-26)22-39-31(18-15-23-8-3-2-4-9-23)37-38-32(39)30(36-33(40)29-12-7-19-34-29)20-25-21-35-28-11-6-5-10-27(25)28/h2-6,8-11,13-14,16-17,21,29-30,34-35H,7,12,15,18-20,22H2,1H3,(H,36,40) GYSPFGJFPWKCMM-UHFFFAOYSA-N 19311 (2R)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]pyrrolidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 19 Growth hormone secretagogue receptor type 1 Homo sapiens 32 8 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19311 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19311&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114402 46519339 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34494 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)c(OC)c1 |r| InChI=1S/C36H39N7O3/c1-45-26-15-13-24(33(19-26)46-2)22-43-34(16-14-23-20-38-29-10-5-3-8-27(23)29)41-42-35(43)32(40-36(44)31-12-7-17-37-31)18-25-21-39-30-11-6-4-9-28(25)30/h3-6,8-11,13,15,19-21,31-32,37-39H,7,12,14,16-18,22H2,1-2H3,(H,40,44) DGVAOEBNVHXSQV-UHFFFAOYSA-N 19312 CHEMBL253126::(2S)-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]pyrrolidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 20 Growth hormone secretagogue receptor type 1 Homo sapiens 5.6 11 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19312 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19312&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113003 46519340 CHEMBL253126 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34495 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)c(OC)c1 |r| InChI=1S/C34H38N6O3/c1-42-26-16-15-24(31(20-26)43-2)22-40-32(17-14-23-9-4-3-5-10-23)38-39-33(40)30(37-34(41)29-13-8-18-35-29)19-25-21-36-28-12-7-6-11-27(25)28/h3-7,9-12,15-16,20-21,29-30,35-36H,8,13-14,17-19,22H2,1-2H3,(H,37,41) OORRBGUZTPSLCB-UHFFFAOYSA-N 19313 (2S)-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]pyrrolidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 21 Growth hormone secretagogue receptor type 1 Homo sapiens 44 32 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19313 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19313&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113001 46519341 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34496 CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)cc1 |r| InChI=1S/C34H38N6O/c1-2-24-14-16-26(17-15-24)23-40-32(19-18-25-9-4-3-5-10-25)38-39-33(40)31(37-34(41)30-13-8-20-35-30)21-27-22-36-29-12-7-6-11-28(27)29/h3-7,9-12,14-17,22,30-31,35-36H,2,8,13,18-21,23H2,1H3,(H,37,41) PBQKDJJUTIMWGR-UHFFFAOYSA-N 19314 (2S)-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]pyrrolidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 22 Growth hormone secretagogue receptor type 1 Homo sapiens 490 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19314 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19314&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648240 46519342 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34497 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1)[C@@H]1CCCN1 |r| InChI=1S/C31H32N6O/c38-31(27-16-9-19-32-27)34-28(20-23-21-33-26-15-8-7-14-25(23)26)30-36-35-29(18-17-22-10-3-1-4-11-22)37(30)24-12-5-2-6-13-24/h1-8,10-15,21,27-28,32-33H,9,16-20H2,(H,34,38) MXZIZDCJSOJXBW-UHFFFAOYSA-N 19315 (2S)-N-[(1R)-2-(1H-indol-3-yl)-1-[4-phenyl-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]ethyl]pyrrolidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 23 Growth hormone secretagogue receptor type 1 Homo sapiens >1000 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19315 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19315&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648241 46519343 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34498 CCc1ccc(cc1)-n1c(CCc2c[nH]c3ccccc23)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1 |r| InChI=1S/C35H37N7O/c1-2-23-13-16-26(17-14-23)42-33(18-15-24-21-37-29-10-5-3-8-27(24)29)40-41-34(42)32(39-35(43)31-12-7-19-36-31)20-25-22-38-30-11-6-4-9-28(25)30/h3-6,8-11,13-14,16-17,21-22,31-32,36-38H,2,7,12,15,18-20H2,1H3,(H,39,43) KXINUWXQXWZNNY-UHFFFAOYSA-N 19316 (2S)-N-[(1R)-1-[4-(4-ethylphenyl)-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]pyrrolidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 24 Growth hormone secretagogue receptor type 1 Homo sapiens 350 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19316 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19316&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648242 46519344 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34499 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2C[C@@H](O)CN2)cc1 |r| InChI=1S/C33H36N6O3/c1-42-26-14-11-23(12-15-26)21-39-31(16-13-22-7-3-2-4-8-22)37-38-32(39)29(36-33(41)30-18-25(40)20-35-30)17-24-19-34-28-10-6-5-9-27(24)28/h2-12,14-15,19,25,29-30,34-35,40H,13,16-18,20-21H2,1H3,(H,36,41) MOJIJWBWUZNLBR-UHFFFAOYSA-N 19317 (2S,4R)-4-hydroxy-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]pyrrolidine-2-carboxamide::(2S,4R)-N-((R)-1-(4-(4-Methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-4-hydroxypyrrolidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 25 Growth hormone secretagogue receptor type 1 Homo sapiens 173 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19317 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19317&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114184 46519345 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34500 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCCNC2)c(OC)c1 |r| InChI=1S/C37H41N7O3/c1-46-28-15-13-26(34(19-28)47-2)23-44-35(16-14-24-21-39-31-11-5-3-9-29(24)31)42-43-36(44)33(41-37(45)25-8-7-17-38-20-25)18-27-22-40-32-12-6-4-10-30(27)32/h3-6,9-13,15,19,21-22,25,33,38-40H,7-8,14,16-18,20,23H2,1-2H3,(H,41,45) QIYOXEQGZPLGBP-UHFFFAOYSA-N 19318 N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-3-carboxamide::Trisubstituted 1,2,4-Triazole, 26 Growth hormone secretagogue receptor type 1 Homo sapiens 6.5 5.3 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19318 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19318&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114097 46509642 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34501 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1Cc1ccccc1)C1CCCNC1 |r| InChI=1S/C35H37N7O/c43-35(26-11-8-18-36-20-26)39-32(19-27-22-38-31-15-7-5-13-29(27)31)34-41-40-33(42(34)23-24-9-2-1-3-10-24)17-16-25-21-37-30-14-6-4-12-28(25)30/h1-7,9-10,12-15,21-22,26,32,36-38H,8,11,16-20,23H2,(H,39,43) DESJRSILBBZHEG-UHFFFAOYSA-N 19319 N-[(1R)-1-{4-benzyl-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-3-carboxamide::Trisubstituted 1,2,4-Triazole, 27 Growth hormone secretagogue receptor type 1 Homo sapiens 13 9.9 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19319 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19319&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114514 46519346 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34502 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1Cc1ccccn1)C1CCCNC1 |r| InChI=1S/C32H35N7O/c40-32(24-11-8-17-33-20-24)36-29(19-25-21-35-28-14-5-4-13-27(25)28)31-38-37-30(16-15-23-9-2-1-3-10-23)39(31)22-26-12-6-7-18-34-26/h1-7,9-10,12-14,18,21,24,29,33,35H,8,11,15-17,19-20,22H2,(H,36,40) SKYNFUYLPSUPDZ-UHFFFAOYSA-N 19320 N-[(1R)-2-(1H-indol-3-yl)-1-[5-(2-phenylethyl)-4-(pyridin-2-ylmethyl)-4H-1,2,4-triazol-3-yl]ethyl]piperidine-3-carboxamide::Trisubstituted 1,2,4-Triazole, 28 Growth hormone secretagogue receptor type 1 Homo sapiens >1000 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19320 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19320&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648243 46519347 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34503 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCNC2)cc1 |r| InChI=1S/C36H39N7O2/c1-45-28-15-12-24(13-16-28)23-43-34(17-14-25-21-38-31-10-4-2-8-29(25)31)41-42-35(43)33(40-36(44)26-7-6-18-37-20-26)19-27-22-39-32-11-5-3-9-30(27)32/h2-5,8-13,15-16,21-22,26,33,37-39H,6-7,14,17-20,23H2,1H3,(H,40,44) FABXLMBOGKCWFI-UHFFFAOYSA-N 19321 (3S)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]piperidine-3-carboxamide::(S)-N-((R)-1-(5-(2-(1H-Indol-3-yl)ethyl)-4-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)piperidine-3-carboxamide::Trisubstituted 1,2,4-Triazole, 29 Growth hormone secretagogue receptor type 1 Homo sapiens 10 2.5 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19321 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19321&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648244 46519348 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34504 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCNC2)cc1 |r| InChI=1S/C34H38N6O2/c1-42-28-16-13-25(14-17-28)23-40-32(18-15-24-8-3-2-4-9-24)38-39-33(40)31(37-34(41)26-10-7-19-35-21-26)20-27-22-36-30-12-6-5-11-29(27)30/h2-6,8-9,11-14,16-17,22,26,31,35-36H,7,10,15,18-21,23H2,1H3,(H,37,41) JEBWQRLWYAVSFG-UHFFFAOYSA-N 19322 (3S)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]piperidine-3-carboxamide::Trisubstituted 1,2,4-Triazole, 30 Growth hormone secretagogue receptor type 1 Homo sapiens 16 10 7.3000 25.00 C Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19322 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19322&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648245 46519349 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34505 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCNC2)cc1 |r| InChI=1S/C34H38N6O2/c1-42-28-16-13-25(14-17-28)23-40-32(18-15-24-8-3-2-4-9-24)38-39-33(40)31(37-34(41)26-10-7-19-35-21-26)20-27-22-36-30-12-6-5-11-29(27)30/h2-6,8-9,11-14,16-17,22,26,31,35-36H,7,10,15,18-21,23H2,1H3,(H,37,41) JEBWQRLWYAVSFG-UHFFFAOYSA-N 19323 (3R)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]piperidine-3-carboxamide::Trisubstituted 1,2,4-Triazole, 31 Growth hormone secretagogue receptor type 1 Homo sapiens 7 36 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19323 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19323&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114289 46519350 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34506 CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCNC2)cc1 |r| InChI=1S/C35H40N6O/c1-2-25-14-16-27(17-15-25)24-41-33(19-18-26-9-4-3-5-10-26)39-40-34(41)32(38-35(42)28-11-8-20-36-22-28)21-29-23-37-31-13-7-6-12-30(29)31/h3-7,9-10,12-17,23,28,32,36-37H,2,8,11,18-22,24H2,1H3,(H,38,42) SINROGNKCLMROR-UHFFFAOYSA-N 19324 (3S)-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-3-carboxamide::Trisubstituted 1,2,4-Triazole, 32 Growth hormone secretagogue receptor type 1 Homo sapiens 130 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19324 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19324&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648246 46519351 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34507 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCCCN2)c(OC)c1 |r| InChI=1S/C37H41N7O3/c1-46-27-16-14-25(34(20-27)47-2)23-44-35(17-15-24-21-39-30-11-5-3-9-28(24)30)42-43-36(44)33(41-37(45)32-13-7-8-18-38-32)19-26-22-40-31-12-6-4-10-29(26)31/h3-6,9-12,14,16,20-22,32-33,38-40H,7-8,13,15,17-19,23H2,1-2H3,(H,41,45) JPUIVPWHWCVOHQ-UHFFFAOYSA-N 19325 N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 33 Growth hormone secretagogue receptor type 1 Homo sapiens 53 18 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19325 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19325&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23644736 46509643 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34508 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCCN2)cc1 |r| InChI=1S/C34H38N6O2/c1-42-27-17-14-25(15-18-27)23-40-32(19-16-24-9-3-2-4-10-24)38-39-33(40)31(37-34(41)30-13-7-8-20-35-30)21-26-22-36-29-12-6-5-11-28(26)29/h2-6,9-12,14-15,17-18,22,30-31,35-36H,7-8,13,16,19-21,23H2,1H3,(H,37,41) ZYAIAJWIMAJKGE-UHFFFAOYSA-N 19326 (2S)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]piperidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 34 Growth hormone secretagogue receptor type 1 Homo sapiens 11 27 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19326 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19326&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114403 46519352 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34509 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)cc1 |r| InChI=1S/C36H39N7O2/c1-45-27-16-13-24(14-17-27)23-43-34(18-15-25-21-38-30-10-4-2-8-28(25)30)41-42-35(43)33(40-36(44)32-12-6-7-19-37-32)20-26-22-39-31-11-5-3-9-29(26)31/h2-5,8-11,13-14,16-17,21-22,32-33,37-39H,6-7,12,15,18-20,23H2,1H3,(H,40,44) FAURKORJKUNELM-UHFFFAOYSA-N 19327 (2R)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]piperidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 35 Growth hormone secretagogue receptor type 1 Homo sapiens 29 8 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19327 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19327&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113370 46519353 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34510 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)cc1 |r| InChI=1S/C34H38N6O2/c1-42-27-17-14-25(15-18-27)23-40-32(19-16-24-9-3-2-4-10-24)38-39-33(40)31(37-34(41)30-13-7-8-20-35-30)21-26-22-36-29-12-6-5-11-28(26)29/h2-6,9-12,14-15,17-18,22,30-31,35-36H,7-8,13,16,19-21,23H2,1H3,(H,37,41) ZYAIAJWIMAJKGE-UHFFFAOYSA-N 19328 (2R)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]piperidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 36 Growth hormone secretagogue receptor type 1 Homo sapiens 23 53 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19328 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19328&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 15945877 46519354 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34511 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)c(OC)c1 |r| InChI=1S/C35H40N6O3/c1-43-27-17-16-25(32(21-27)44-2)23-41-33(18-15-24-10-4-3-5-11-24)39-40-34(41)31(38-35(42)30-14-8-9-19-36-30)20-26-22-37-29-13-7-6-12-28(26)29/h3-7,10-13,16-17,21-22,30-31,36-37H,8-9,14-15,18-20,23H2,1-2H3,(H,38,42) LTZQHKKUJQVOBT-UHFFFAOYSA-N 19329 (2R)-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 37 Growth hormone secretagogue receptor type 1 Homo sapiens 134 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19329 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19329&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16112901 46519355 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34512 CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)cc1 |r| InChI=1S/C35H40N6O/c1-2-25-15-17-27(18-16-25)24-41-33(20-19-26-10-4-3-5-11-26)39-40-34(41)32(38-35(42)31-14-8-9-21-36-31)22-28-23-37-30-13-7-6-12-29(28)30/h3-7,10-13,15-18,23,31-32,36-37H,2,8-9,14,19-22,24H2,1H3,(H,38,42) QDDCAAMEEYUGOX-UHFFFAOYSA-N 19330 (2R)-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 38 Growth hormone secretagogue receptor type 1 Homo sapiens 375 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19330&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648247 46519356 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34513 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| InChI=1S/C36H39N7O2/c1-45-28-13-10-24(11-14-28)23-43-34(15-12-26-21-38-31-8-4-2-6-29(26)31)41-42-35(43)33(40-36(44)25-16-18-37-19-17-25)20-27-22-39-32-9-5-3-7-30(27)32/h2-11,13-14,21-22,25,33,37-39H,12,15-20,23H2,1H3,(H,40,44) MUMIOCPFGKBWRY-UHFFFAOYSA-N 19331 CHEMBL266063::N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 39 Growth hormone secretagogue receptor type 1 Homo sapiens 0.3 3.0 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19331 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19331&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114292 46519357 CHEMBL266063 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34514 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| InChI=1S/C34H38N6O2/c1-42-28-14-11-25(12-15-28)23-40-32(16-13-24-7-3-2-4-8-24)38-39-33(40)31(37-34(41)26-17-19-35-20-18-26)21-27-22-36-30-10-6-5-9-29(27)30/h2-12,14-15,22,26,31,35-36H,13,16-21,23H2,1H3,(H,37,41) QWRYEBIUSXZEDO-UHFFFAOYSA-N 19332 N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 40 Growth hormone secretagogue receptor type 1 Homo sapiens 0.6 1.6 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19332 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19332&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114291 46519358 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34515 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)c(OC)c1 |r| InChI=1S/C37H41N7O3/c1-46-28-13-11-26(34(20-28)47-2)23-44-35(14-12-25-21-39-31-9-5-3-7-29(25)31)42-43-36(44)33(41-37(45)24-15-17-38-18-16-24)19-27-22-40-32-10-6-4-8-30(27)32/h3-11,13,20-22,24,33,38-40H,12,14-19,23H2,1-2H3,(H,41,45) BRFWOWNZIQIQTQ-UHFFFAOYSA-N 19333 N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 41 Growth hormone secretagogue receptor type 1 Homo sapiens 0.5 0.6 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19333 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19333&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16114096 46509644 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34516 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)c(OC)c1 |r| InChI=1S/C35H40N6O3/c1-43-28-14-13-26(32(21-28)44-2)23-41-33(15-12-24-8-4-3-5-9-24)39-40-34(41)31(38-35(42)25-16-18-36-19-17-25)20-27-22-37-30-11-7-6-10-29(27)30/h3-11,13-14,21-22,25,31,36-37H,12,15-20,23H2,1-2H3,(H,38,42) TYOMLAMYBVQIJW-UHFFFAOYSA-N 19334 N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 42 Growth hormone secretagogue receptor type 1 Homo sapiens 0.9 6.1 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19334 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19334&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16112900 46519359 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34517 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1Cc1ccccc1)C1CCNCC1 |r| InChI=1S/C35H37N7O/c43-35(25-16-18-36-19-17-25)39-32(20-27-22-38-31-13-7-5-11-29(27)31)34-41-40-33(42(34)23-24-8-2-1-3-9-24)15-14-26-21-37-30-12-6-4-10-28(26)30/h1-13,21-22,25,32,36-38H,14-20,23H2,(H,39,43) FRKGNEAURFFNKA-UHFFFAOYSA-N 19335 N-[(1R)-1-{4-benzyl-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 43 Growth hormone secretagogue receptor type 1 Homo sapiens 24 5.4 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19335 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19335&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113710 46519360 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34518 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1)C1CCNCC1 |r| InChI=1S/C32H34N6O/c39-32(24-17-19-33-20-18-24)35-29(21-25-22-34-28-14-8-7-13-27(25)28)31-37-36-30(16-15-23-9-3-1-4-10-23)38(31)26-11-5-2-6-12-26/h1-14,22,24,29,33-34H,15-21H2,(H,35,39) HTCGKPAHGQFWCF-UHFFFAOYSA-N 19336 N-[(1R)-2-(1H-indol-3-yl)-1-[4-phenyl-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 44 Growth hormone secretagogue receptor type 1 Homo sapiens 468 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19336 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19336&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648248 46519361 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34519 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1-c1ccccc1)C1CCNCC1 |r| InChI=1S/C34H35N7O/c42-34(23-16-18-35-19-17-23)38-31(20-25-22-37-30-13-7-5-11-28(25)30)33-40-39-32(41(33)26-8-2-1-3-9-26)15-14-24-21-36-29-12-6-4-10-27(24)29/h1-13,21-23,31,35-37H,14-20H2,(H,38,42) GQRRMXRDZHSZNL-UHFFFAOYSA-N 19337 N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-phenyl-4H-1,2,4-triazol-3-yl}ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 45 Growth hormone secretagogue receptor type 1 Homo sapiens 70 2.3 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19337 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19337&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648249 46519362 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34520 CCc1ccc(cc1)-n1c(CCc2c[nH]c3ccccc23)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C1CCNCC1 |r| InChI=1S/C36H39N7O/c1-2-24-11-14-28(15-12-24)43-34(16-13-26-22-38-31-9-5-3-7-29(26)31)41-42-35(43)33(40-36(44)25-17-19-37-20-18-25)21-27-23-39-32-10-6-4-8-30(27)32/h3-12,14-15,22-23,25,33,37-39H,2,13,16-21H2,1H3,(H,40,44) SXXCJMWDJJZVGN-UHFFFAOYSA-N 19338 N-[(1R)-1-[4-(4-ethylphenyl)-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 46 Growth hormone secretagogue receptor type 1 Homo sapiens 96 15 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19338 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19338&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648250 46519363 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34521 CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| InChI=1S/C35H40N6O/c1-2-25-12-14-27(15-13-25)24-41-33(17-16-26-8-4-3-5-9-26)39-40-34(41)32(38-35(42)28-18-20-36-21-19-28)22-29-23-37-31-11-7-6-10-30(29)31/h3-15,23,28,32,36-37H,2,16-22,24H2,1H3,(H,38,42) PROMAYDRALXCHH-UHFFFAOYSA-N 19339 N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 47 Growth hormone secretagogue receptor type 1 Homo sapiens 19 7.7 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19339 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19339&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113248 46519364 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34522 COc1ccc(c(OC)c1)-n1c(CCc2ccccc2)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C1CCNCC1 |r,wU:23.38,(4.57,-2.49,;3.09,-2.1,;2.48,-.68,;.95,-.51,;.33,.91,;1.25,2.14,;2.78,1.97,;3.7,3.2,;5.24,3.2,;3.39,.55,;.85,3.63,;2.12,4.51,;3.57,4,;4.74,5.01,;4.74,6.55,;3.4,7.32,;3.4,8.86,;4.74,9.63,;6.07,8.86,;6.07,7.32,;1.67,5.98,;.13,6.02,;-.37,4.56,;-1.71,3.79,;-2.48,2.46,;-2.48,.92,;-1,.49,;-.95,-1.05,;-2.41,-1.57,;-2.99,-3,;-4.52,-3.2,;-5.46,-1.98,;-4.87,-.56,;-3.35,-.35,;-3.04,4.56,;-4.38,3.79,;-4.38,2.25,;-5.71,4.56,;-7.04,3.79,;-8.38,4.56,;-8.38,6.1,;-7.04,6.87,;-5.71,6.1,)| InChI=1S/C34H38N6O3/c1-42-26-13-14-30(31(21-26)43-2)40-32(15-12-23-8-4-3-5-9-23)38-39-33(40)29(37-34(41)24-16-18-35-19-17-24)20-25-22-36-28-11-7-6-10-27(25)28/h3-11,13-14,21-22,24,29,35-36H,12,15-20H2,1-2H3,(H,37,41) NNGYCMSDZAWHMF-UHFFFAOYSA-N 19340 N-[(1R)-1-[4-(2,4-dimethoxyphenyl)-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 48 Growth hormone secretagogue receptor type 1 Homo sapiens 63 14 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19340 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19340&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648251 46519365 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34523 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(Cc2ccccc2)n1Cc1ccccn1)C1CCNCC1 |r| InChI=1S/C31H33N7O/c39-31(23-13-16-32-17-14-23)35-28(19-24-20-34-27-12-5-4-11-26(24)27)30-37-36-29(18-22-8-2-1-3-9-22)38(30)21-25-10-6-7-15-33-25/h1-12,15,20,23,28,32,34H,13-14,16-19,21H2,(H,35,39) RHLOWCZCPRHIBS-UHFFFAOYSA-N 19341 N-[(1R)-1-[5-benzyl-4-(pyridin-2-ylmethyl)-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 49 Growth hormone secretagogue receptor type 1 Homo sapiens >1000 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19341 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19341&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648252 46519366 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34524 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1Cc1cccs1)C1CCNCC1 |r| InChI=1S/C31H34N6OS/c38-31(23-14-16-32-17-15-23)34-28(19-24-20-33-27-11-5-4-10-26(24)27)30-36-35-29(13-12-22-7-2-1-3-8-22)37(30)21-25-9-6-18-39-25/h1-11,18,20,23,28,32-33H,12-17,19,21H2,(H,34,38) TVWIMSXDTYKRGD-UHFFFAOYSA-N 19342 N-[(1R)-2-(1H-indol-3-yl)-1-[5-(2-phenylethyl)-4-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl]ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 50 Growth hormone secretagogue receptor type 1 Homo sapiens 255 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19342 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19342&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 16113473 46519367 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34525 O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1Cc1ccco1)C1CCNCC1 |r| InChI=1S/C31H34N6O2/c38-31(23-14-16-32-17-15-23)34-28(19-24-20-33-27-11-5-4-10-26(24)27)30-36-35-29(13-12-22-7-2-1-3-8-22)37(30)21-25-9-6-18-39-25/h1-11,18,20,23,28,32-33H,12-17,19,21H2,(H,34,38) QFFMNYRWGUWLOU-UHFFFAOYSA-N 19343 N-[(1R)-1-[4-(furan-2-ylmethyl)-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 51 Growth hormone secretagogue receptor type 1 Homo sapiens 560 183 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19343 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19343&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648253 46519368 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34526 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)cc1 |r| InChI=1S/C35H38N8O2/c1-45-26-13-10-23(11-14-26)22-43-33(15-12-24-19-38-29-8-4-2-6-27(24)29)41-42-34(43)31(40-35(44)32-21-36-16-17-37-32)18-25-20-39-30-9-5-3-7-28(25)30/h2-11,13-14,19-20,31-32,36-39H,12,15-18,21-22H2,1H3,(H,40,44) URKWPFYDVSHCEI-UHFFFAOYSA-N 19344 N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-4H-1,2,4-triazol-3-yl}ethyl]piperazine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 52 Growth hormone secretagogue receptor type 1 Homo sapiens 18 8.7 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19344 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19344&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648254 46519369 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34527 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)cc1 |r| InChI=1S/C33H37N7O2/c1-42-26-14-11-24(12-15-26)22-40-31(16-13-23-7-3-2-4-8-23)38-39-32(40)29(37-33(41)30-21-34-17-18-35-30)19-25-20-36-28-10-6-5-9-27(25)28/h2-12,14-15,20,29-30,34-36H,13,16-19,21-22H2,1H3,(H,37,41) AVTOEUFCBKGYLY-UHFFFAOYSA-N 19345 N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]piperazine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 53 Growth hormone secretagogue receptor type 1 Homo sapiens 54 12 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19345 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19345&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648255 46519370 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34528 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)c(OC)c1 |r| InChI=1S/C36H40N8O3/c1-46-26-13-11-24(33(18-26)47-2)22-44-34(14-12-23-19-39-29-9-5-3-7-27(23)29)42-43-35(44)31(41-36(45)32-21-37-15-16-38-32)17-25-20-40-30-10-6-4-8-28(25)30/h3-11,13,18-20,31-32,37-40H,12,14-17,21-22H2,1-2H3,(H,41,45) BEAVQQJSWGACGL-UHFFFAOYSA-N 19346 N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1H-indol-3-yl)ethyl]-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperazine-2-carboxamide::(R,S)-N-((R)-1-(5-(2-(1H-Indol-3-yl)ethyl)-4-(2,4-dimethoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)piperazine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 54 Growth hormone secretagogue receptor type 1 Homo sapiens 32 5 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19346 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19346&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23644737 46509645 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34529 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)c(OC)c1 |r| InChI=1S/C34H39N7O3/c1-43-26-14-13-24(31(19-26)44-2)22-41-32(15-12-23-8-4-3-5-9-23)39-40-33(41)29(38-34(42)30-21-35-16-17-36-30)18-25-20-37-28-11-7-6-10-27(25)28/h3-11,13-14,19-20,29-30,35-37H,12,15-18,21-22H2,1-2H3,(H,38,42) AHJZFOKHUIPNSR-UHFFFAOYSA-N 19347 N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperazine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 55 Growth hormone secretagogue receptor type 1 Homo sapiens 35 19.6 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19347 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19347&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648256 46519371 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34530 CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)cc1 |r| InChI=1S/C34H39N7O/c1-2-24-12-14-26(15-13-24)23-41-32(17-16-25-8-4-3-5-9-25)39-40-33(41)30(38-34(42)31-22-35-18-19-36-31)20-27-21-37-29-11-7-6-10-28(27)29/h3-15,21,30-31,35-37H,2,16-20,22-23H2,1H3,(H,38,42) SUNBOSBAHPNJDU-UHFFFAOYSA-N 19348 N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperazine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 56 Growth hormone secretagogue receptor type 1 Homo sapiens 178 143 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19348 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19348&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648257 46519372 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34531 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCOCC2)cc1 |r| InChI=1S/C34H37N5O3/c1-41-28-14-11-25(12-15-28)23-39-32(16-13-24-7-3-2-4-8-24)37-38-33(39)31(36-34(40)26-17-19-42-20-18-26)21-27-22-35-30-10-6-5-9-29(27)30/h2-12,14-15,22,26,31,35H,13,16-21,23H2,1H3,(H,36,40) QILFYFBRTDATBA-UHFFFAOYSA-N 19349 N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]oxane-4-carboxamide::Trisubstituted 1,2,4-Triazole, 57 Growth hormone secretagogue receptor type 1 Homo sapiens 6 51 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19349 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19349&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648258 46519373 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34532 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCCCC2)cc1 |r| InChI=1S/C35H39N5O2/c1-42-29-19-16-26(17-20-29)24-40-33(21-18-25-10-4-2-5-11-25)38-39-34(40)32(37-35(41)27-12-6-3-7-13-27)22-28-23-36-31-15-9-8-14-30(28)31/h2,4-5,8-11,14-17,19-20,23,27,32,36H,3,6-7,12-13,18,21-22,24H2,1H3,(H,37,41) DKRAQXRUFKWDKN-UHFFFAOYSA-N 19350 N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]cyclohexanecarboxamide::Trisubstituted 1,2,4-Triazole, 58 Growth hormone secretagogue receptor type 1 Homo sapiens 18 390 Curated from the literature by BindingDB 10.1021/jm0704550 10.7270/Q2HD7SZ4 17927165 aid1797843 Moulin, A; Demange, L; Bergé, G; Gagne, D; Ryan, J; Mousseaux, D; Heitz, A; Perrissoud, D; Locatelli, V; Torsello, A; Galleyrand, JC; Fehrentz, JA; Martinez, J 11/15/2007 12/10/2007 Cnrs http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19350 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19350&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23648259 46519374 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34533 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1 InChI=1S/C20H23N5O2S/c1-3-17-18(19(21)25-20(22)24-17)14-6-8-15(9-7-14)23-12-13-4-10-16(11-5-13)28(2,26)27/h4-11,23H,3,12H2,1-2H3,(H4,21,22,24,25) IIMYRTZDWODUAY-UHFFFAOYSA-N 19351 6-ethyl-5-(4-{[(4-methanesulfonylphenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::CHEMBL203280::JMC492568 7b::2,4-diaminopyrimidine-based antagonist, 4c Growth hormone secretagogue receptor type 1 Homo sapiens 7 19 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19351&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11538533 46519375 CHEMBL203280 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34534 CCc1nc(N)nc(N)c1-c1ccc2n(Cc3ccc(cc3)S(C)(=O)=O)cnc2c1 InChI=1S/C21H22N6O2S/c1-3-16-19(20(22)26-21(23)25-16)14-6-9-18-17(10-14)24-12-27(18)11-13-4-7-15(8-5-13)30(2,28)29/h4-10,12H,3,11H2,1-2H3,(H4,22,23,25,26) LSEHXMWYQVYWPQ-UHFFFAOYSA-N 19352 6-ethyl-5-{1-[(4-methanesulfonylphenyl)methyl]-1H-1,3-benzodiazol-5-yl}pyrimidine-2,4-diamine::2,4-diaminopyrimidine-based antagonist, 7 Growth hormone secretagogue receptor type 1 Homo sapiens 4 11 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19352 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19352&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846463 46519376 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34535 CCc1nc(N)nc(N)c1-c1ccc2n(Cc3ccc(cc3)S(C)(=O)=O)c(nc2c1)C1CCCC1 InChI=1S/C26H30N6O2S/c1-3-20-23(24(27)31-26(28)30-20)18-10-13-22-21(14-18)29-25(17-6-4-5-7-17)32(22)15-16-8-11-19(12-9-16)35(2,33)34/h8-14,17H,3-7,15H2,1-2H3,(H4,27,28,30,31) VLHZQLDSBFPCII-UHFFFAOYSA-N 19353 5-{2-cyclopentyl-1-[(4-methanesulfonylphenyl)methyl]-1H-1,3-benzodiazol-5-yl}-6-ethylpyrimidine-2,4-diamine::2,4-diaminopyrimidine-based antagonist, 8a Growth hormone secretagogue receptor type 1 Homo sapiens 8 109 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19353 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19353&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846624 46519377 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34536 CCc1nc(N)nc(N)c1-c1ccc2n(Cc3ccc(cc3)S(C)(=O)=O)c(nc2c1)-c1ccccc1 InChI=1S/C27H26N6O2S/c1-3-21-24(25(28)32-27(29)31-21)19-11-14-23-22(15-19)30-26(18-7-5-4-6-8-18)33(23)16-17-9-12-20(13-10-17)36(2,34)35/h4-15H,3,16H2,1-2H3,(H4,28,29,31,32) OJVARHYUTXXZJR-UHFFFAOYSA-N 19354 6-ethyl-5-{1-[(4-methanesulfonylphenyl)methyl]-2-phenyl-1H-1,3-benzodiazol-5-yl}pyrimidine-2,4-diamine::2,4-diaminopyrimidine-based antagonist, 8b Growth hormone secretagogue receptor type 1 Homo sapiens 16 249 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19354 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19354&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846625 46519378 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34537 CC(=O)Nc1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1 InChI=1S/C20H21N5O2/c1-13(26)23-16-9-7-15(8-10-16)18-17(24-20(22)25-19(18)21)12-27-11-14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,23,26)(H4,21,22,24,25) RHVHGEHIJUENCE-UHFFFAOYSA-N 19355 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)acetamide::2,4-diaminopyrimidine-based antagonist, 13a Growth hormone secretagogue receptor type 1 Homo sapiens 2270 >10000 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19355&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846627 46519379 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34538 CCC(=O)Nc1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1 InChI=1S/C21H23N5O2/c1-2-18(27)24-16-10-8-15(9-11-16)19-17(25-21(23)26-20(19)22)13-28-12-14-6-4-3-5-7-14/h3-11H,2,12-13H2,1H3,(H,24,27)(H4,22,23,25,26) ABCMLBFIEBJOLA-UHFFFAOYSA-N 19356 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)propanamide::2,4-diaminopyrimidine-based antagonist, 13b Growth hormone secretagogue receptor type 1 Homo sapiens 221 >10000 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19356 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19356&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11314908 46519380 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34539 CC(C)CC(=O)Nc1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1 InChI=1S/C23H27N5O2/c1-15(2)12-20(29)26-18-10-8-17(9-11-18)21-19(27-23(25)28-22(21)24)14-30-13-16-6-4-3-5-7-16/h3-11,15H,12-14H2,1-2H3,(H,26,29)(H4,24,25,27,28) QGKYEEPHMFVUEN-UHFFFAOYSA-N 19357 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-3-methylbutanamide::2,4-diaminopyrimidine-based antagonist, 13c Growth hormone secretagogue receptor type 1 Homo sapiens 72 108 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19357 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19357&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11211892 46519381 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34540 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)C2CC2)cc1 InChI=1S/C22H23N5O2/c23-20-19(15-8-10-17(11-9-15)25-21(28)16-6-7-16)18(26-22(24)27-20)13-29-12-14-4-2-1-3-5-14/h1-5,8-11,16H,6-7,12-13H2,(H,25,28)(H4,23,24,26,27) ATKRWWYTIGCNEA-UHFFFAOYSA-N 19358 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)cyclopropanecarboxamide::2,4-diaminopyrimidine-based antagonist, 13d Growth hormone secretagogue receptor type 1 Homo sapiens 66 188 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19358 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19358&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11349789 46519382 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34541 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)C2CCCC2)cc1 InChI=1S/C24H27N5O2/c25-22-21(17-10-12-19(13-11-17)27-23(30)18-8-4-5-9-18)20(28-24(26)29-22)15-31-14-16-6-2-1-3-7-16/h1-3,6-7,10-13,18H,4-5,8-9,14-15H2,(H,27,30)(H4,25,26,28,29) ULACJMAZFIEDES-UHFFFAOYSA-N 19359 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)cyclopentanecarboxamide::2,4-diaminopyrimidine-based antagonist, 13e Growth hormone secretagogue receptor type 1 Homo sapiens 18 40 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19359 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19359&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11452801 46519383 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34542 CN(C(=O)C1CCCC1)c1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1 InChI=1S/C25H29N5O2/c1-30(24(31)19-9-5-6-10-19)20-13-11-18(12-14-20)22-21(28-25(27)29-23(22)26)16-32-15-17-7-3-2-4-8-17/h2-4,7-8,11-14,19H,5-6,9-10,15-16H2,1H3,(H4,26,27,28,29) VRFGCTMNTASNRG-UHFFFAOYSA-N 19360 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-N-methylcyclopentanecarboxamide::2,4-diaminopyrimidine-based antagonist, 13f Growth hormone secretagogue receptor type 1 Homo sapiens 1670 >10000 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19360 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19360&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846628 46519384 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34543 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)c2ccncc2)cc1 InChI=1S/C24H22N6O2/c25-22-21(20(29-24(26)30-22)15-32-14-16-4-2-1-3-5-16)17-6-8-19(9-7-17)28-23(31)18-10-12-27-13-11-18/h1-13H,14-15H2,(H,28,31)(H4,25,26,29,30) VARCCLXJDPYZBP-UHFFFAOYSA-N 19361 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)pyridine-4-carboxamide::2,4-diaminopyrimidine-based antagonist, 13h Growth hormone secretagogue receptor type 1 Homo sapiens 3080 >10000 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19361 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19361&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846630 46519385 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34544 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)Cc2cccnc2)cc1 InChI=1S/C25H24N6O2/c26-24-23(21(30-25(27)31-24)16-33-15-17-5-2-1-3-6-17)19-8-10-20(11-9-19)29-22(32)13-18-7-4-12-28-14-18/h1-12,14H,13,15-16H2,(H,29,32)(H4,26,27,30,31) MFCPBMNBYFSYKR-UHFFFAOYSA-N 19362 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-2-(pyridin-3-yl)acetamide::2,4-diaminopyrimidine-based antagonist, 13i Growth hormone secretagogue receptor type 1 Homo sapiens >1000 >10000 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19362 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19362&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846799 46519386 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34545 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)c2ccsc2)cc1 InChI=1S/C23H21N5O2S/c24-21-20(16-6-8-18(9-7-16)26-22(29)17-10-11-31-14-17)19(27-23(25)28-21)13-30-12-15-4-2-1-3-5-15/h1-11,14H,12-13H2,(H,26,29)(H4,24,25,27,28) WMIRSHGNCSPTIB-UHFFFAOYSA-N 19363 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)thiophene-3-carboxamide::2,4-diaminopyrimidine-based antagonist, 13j Growth hormone secretagogue receptor type 1 Homo sapiens 126 >10000 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19363 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19363&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11373823 46519387 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34546 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)Cc2ccsc2)cc1 InChI=1S/C24H23N5O2S/c25-23-22(20(28-24(26)29-23)14-31-13-16-4-2-1-3-5-16)18-6-8-19(9-7-18)27-21(30)12-17-10-11-32-15-17/h1-11,15H,12-14H2,(H,27,30)(H4,25,26,28,29) JBHLOEIRCPTUBB-UHFFFAOYSA-N 19364 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-2-(thiophen-3-yl)acetamide::2,4-diaminopyrimidine-based antagonist, 13k Growth hormone secretagogue receptor type 1 Homo sapiens 70 382 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19364&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11178309 46519388 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34547 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)Cc2ccsc2Br)cc1 InChI=1S/C24H22BrN5O2S/c25-22-17(10-11-33-22)12-20(31)28-18-8-6-16(7-9-18)21-19(29-24(27)30-23(21)26)14-32-13-15-4-2-1-3-5-15/h1-11H,12-14H2,(H,28,31)(H4,26,27,29,30) UXTOJBWHLPSCPP-UHFFFAOYSA-N 19365 2-(2-bromothiophen-3-yl)-N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)acetamide::2,4-diaminopyrimidine-based antagonist, 13l Growth hormone secretagogue receptor type 1 Homo sapiens 41 137 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19365 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19365&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11455251 46519389 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34548 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)Cc2ccccc2)cc1 InChI=1S/C26H25N5O2/c27-25-24(22(30-26(28)31-25)17-33-16-19-9-5-2-6-10-19)20-11-13-21(14-12-20)29-23(32)15-18-7-3-1-4-8-18/h1-14H,15-17H2,(H,29,32)(H4,27,28,30,31) CQMPFWNJLTXKTD-UHFFFAOYSA-N 19366 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-2-phenylacetamide::2,4-diaminopyrimidine-based antagonist, 13m Growth hormone secretagogue receptor type 1 Homo sapiens 37 408 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19366 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19366&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11430583 46519390 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34549 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)CCc2ccccc2)cc1 InChI=1S/C27H27N5O2/c28-26-25(23(31-27(29)32-26)18-34-17-20-9-5-2-6-10-20)21-12-14-22(15-13-21)30-24(33)16-11-19-7-3-1-4-8-19/h1-10,12-15H,11,16-18H2,(H,30,33)(H4,28,29,31,32) PAJCBTPKTYHKAX-UHFFFAOYSA-N 19367 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-3-phenylpropanamide::2,4-diaminopyrimidine-based antagonist, 13n Growth hormone secretagogue receptor type 1 Homo sapiens 47 343 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19367 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19367&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11751384 46519391 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34550 CC(C)NC(=O)Nc1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1 InChI=1S/C22H26N6O2/c1-14(2)25-22(29)26-17-10-8-16(9-11-17)19-18(27-21(24)28-20(19)23)13-30-12-15-6-4-3-5-7-15/h3-11,14H,12-13H2,1-2H3,(H2,25,26,29)(H4,23,24,27,28) WRFODILBPBFVTC-UHFFFAOYSA-N 19368 1-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-3-propan-2-ylurea::2,4-diaminopyrimidine-based antagonist, 14a Growth hormone secretagogue receptor type 1 Homo sapiens 56 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19368 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19368&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11154001 46519392 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34551 CC(C)N(C)C(=O)Nc1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1 InChI=1S/C23H28N6O2/c1-15(2)29(3)23(30)26-18-11-9-17(10-12-18)20-19(27-22(25)28-21(20)24)14-31-13-16-7-5-4-6-8-16/h4-12,15H,13-14H2,1-3H3,(H,26,30)(H4,24,25,27,28) CDUBDPSLROHHKZ-UHFFFAOYSA-N 19369 1-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-3-methyl-3-propan-2-ylurea::2,4-diaminopyrimidine-based antagonist, 14b Growth hormone secretagogue receptor type 1 Homo sapiens >10000 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19369 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19369&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846800 46519393 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34552 CC(C)(C)NC(=O)Nc1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1 InChI=1S/C23H28N6O2/c1-23(2,3)29-22(30)26-17-11-9-16(10-12-17)19-18(27-21(25)28-20(19)24)14-31-13-15-7-5-4-6-8-15/h4-12H,13-14H2,1-3H3,(H2,26,29,30)(H4,24,25,27,28) MLBYOWASRACYDH-UHFFFAOYSA-N 19370 3-tert-butyl-1-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)urea::2,4-diaminopyrimidine-based antagonist, 14c Growth hormone secretagogue receptor type 1 Homo sapiens 7 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19370 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19370&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11441554 46519394 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34553 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)Nc2ccccc2)cc1 InChI=1S/C25H24N6O2/c26-23-22(21(30-24(27)31-23)16-33-15-17-7-3-1-4-8-17)18-11-13-20(14-12-18)29-25(32)28-19-9-5-2-6-10-19/h1-14H,15-16H2,(H2,28,29,32)(H4,26,27,30,31) PYMAUABSKWWTGR-UHFFFAOYSA-N 19371 3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-1-phenylurea::2,4-diaminopyrimidine-based antagonist, 14d Growth hormone secretagogue receptor type 1 Homo sapiens 88 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19371 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19371&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11442040 46519395 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34554 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)NCc2ccccc2)cc1 InChI=1S/C26H26N6O2/c27-24-23(22(31-25(28)32-24)17-34-16-19-9-5-2-6-10-19)20-11-13-21(14-12-20)30-26(33)29-15-18-7-3-1-4-8-18/h1-14H,15-17H2,(H2,29,30,33)(H4,27,28,31,32) CRWVLECQBDATTM-UHFFFAOYSA-N 19372 1-benzyl-3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)urea::2,4-diaminopyrimidine-based antagonist, 14e Growth hormone secretagogue receptor type 1 Homo sapiens 34 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19372 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19372&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11248021 46519396 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34555 CC(NC(=O)Nc1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1)c1ccccc1 InChI=1S/C27H28N6O2/c1-18(20-10-6-3-7-11-20)30-27(34)31-22-14-12-21(13-15-22)24-23(32-26(29)33-25(24)28)17-35-16-19-8-4-2-5-9-19/h2-15,18H,16-17H2,1H3,(H2,30,31,34)(H4,28,29,32,33) VZPNUPDYOSDSLB-UHFFFAOYSA-N 19373 3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-1-(1-phenylethyl)urea::2,4-diaminopyrimidine-based antagonist, 14f Growth hormone secretagogue receptor type 1 Homo sapiens 10 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19373 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19373&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11351838 46519397 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34556 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)NCCc2ccccc2)cc1 InChI=1S/C27H28N6O2/c28-25-24(23(32-26(29)33-25)18-35-17-20-9-5-2-6-10-20)21-11-13-22(14-12-21)31-27(34)30-16-15-19-7-3-1-4-8-19/h1-14H,15-18H2,(H2,30,31,34)(H4,28,29,32,33) LGGIVTCQXBEAOP-UHFFFAOYSA-N 19374 3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)-1-(2-phenylethyl)urea::2,4-diaminopyrimidine-based antagonist, 14g Growth hormone secretagogue receptor type 1 Homo sapiens 7 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19374 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19374&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11340329 46519398 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34557 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NC(=O)C2CCCO2)cc1 InChI=1S/C23H25N5O3/c24-21-20(16-8-10-17(11-9-16)26-22(29)19-7-4-12-31-19)18(27-23(25)28-21)14-30-13-15-5-2-1-3-6-15/h1-3,5-6,8-11,19H,4,7,12-14H2,(H,26,29)(H4,24,25,27,28) PPWORKYMGYFOCE-UHFFFAOYSA-N 19375 N-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)oxolane-2-carboxamide::2,4-diaminopyrimidine-based antagonist, 13g Growth hormone secretagogue receptor type 1 Homo sapiens 391 >10000 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm060461g 10.7270/Q2CN726R 16854051 aid1797845 Xin, Z; Serby, MD; Zhao, H; Kosogof, C; Szczepankiewicz, BG; Liu, M; Liu, B; Hutchins, CW; Sarris, KA; Hoff, ED; Falls, HD; Lin, CW; Ogiela, CA; Collins, CA; Brune, ME; Bush, EN; Droz, BA; Fey, TA; Knourek-Segel, VE; Shapiro, R; Jacobson, PB; Beno, DW; Turner, TM; Sham, HL; Liu, G 7/27/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19375 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19375&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11846629 46519399 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34563 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(Cl)cc2)cc1 InChI=1S/C19H20ClN5/c1-2-16-17(18(21)25-19(22)24-16)13-5-9-15(10-6-13)23-11-12-3-7-14(20)8-4-12/h3-10,23H,2,11H2,1H3,(H4,21,22,24,25) RZMJPDSNFIAJRD-UHFFFAOYSA-N 19376 5-(4-{[(4-chlorophenyl)methyl]amino}phenyl)-6-ethylpyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 7a Growth hormone secretagogue receptor type 1 Homo sapiens 310 1380 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19376 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19376&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11221946 46509646 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34564 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)cc1 InChI=1S/C20H23N5O2S/c1-3-17-18(19(21)25-20(22)24-17)14-6-8-15(9-7-14)23-12-13-4-10-16(11-5-13)28(2,26)27/h4-11,23H,3,12H2,1-2H3,(H4,21,22,24,25) IIMYRTZDWODUAY-UHFFFAOYSA-N 19351 6-ethyl-5-(4-{[(4-methanesulfonylphenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::CHEMBL203280::JMC492568 7b::2,4-diaminopyrimidine-based antagonist, 4c Growth hormone secretagogue receptor type 1 Homo sapiens 7.4 12 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19351&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11538533 46519375 CHEMBL203280 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34565 CCc1nc(N)nc(N)c1-c1ccc(NCc2cc(F)c(c(F)c2)S(C)(=O)=O)cc1 InChI=1S/C20H21F2N5O2S/c1-3-16-17(19(23)27-20(24)26-16)12-4-6-13(7-5-12)25-10-11-8-14(21)18(15(22)9-11)30(2,28)29/h4-9,25H,3,10H2,1-2H3,(H4,23,24,26,27) YFGOCVGEMQNGLD-UHFFFAOYSA-N 19377 5-(4-{[(3,5-difluoro-4-methanesulfonylphenyl)methyl]amino}phenyl)-6-ethylpyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 7c Growth hormone secretagogue receptor type 1 Homo sapiens 2.4 45 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19377 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19377&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11683469 46519400 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34566 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)[N+]([O-])=O)cc1 InChI=1S/C19H20N6O2/c1-2-16-17(18(20)24-19(21)23-16)13-5-7-14(8-6-13)22-11-12-3-9-15(10-4-12)25(26)27/h3-10,22H,2,11H2,1H3,(H4,20,21,23,24) YNLJPWBIYDXHDX-UHFFFAOYSA-N 19378 6-ethyl-5-(4-{[(4-nitrophenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 7d Growth hormone secretagogue receptor type 1 Homo sapiens 11 23 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19378 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19378&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11337482 46519401 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34567 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)C(C)=O)cc1 InChI=1S/C21H23N5O/c1-3-18-19(20(22)26-21(23)25-18)16-8-10-17(11-9-16)24-12-14-4-6-15(7-5-14)13(2)27/h4-11,24H,3,12H2,1-2H3,(H4,22,23,25,26) RBQSARCIGLNTFF-UHFFFAOYSA-N 19379 1-[4-({[4-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]amino}methyl)phenyl]ethan-1-one::2,4-diaminopyrimidine derivative, 7e Growth hormone secretagogue receptor type 1 Homo sapiens 57 110 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19379 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19379&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11537800 46519402 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34568 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)C(C)O)cc1 InChI=1S/C21H25N5O/c1-3-18-19(20(22)26-21(23)25-18)16-8-10-17(11-9-16)24-12-14-4-6-15(7-5-14)13(2)27/h4-11,13,24,27H,3,12H2,1-2H3,(H4,22,23,25,26) KXKYKXBERNRULI-UHFFFAOYSA-N 19380 1-[4-({[4-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]amino}methyl)phenyl]ethan-1-ol::2,4-diaminopyrimidine derivative, 7f Growth hormone secretagogue receptor type 1 Homo sapiens 13 110 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19380 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19380&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11523411 46519403 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34569 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)C#N)cc1 InChI=1S/C20H20N6/c1-2-17-18(19(22)26-20(23)25-17)15-7-9-16(10-8-15)24-12-14-5-3-13(11-21)4-6-14/h3-10,24H,2,12H2,1H3,(H4,22,23,25,26) FXWGMDQMRCPBHI-UHFFFAOYSA-N 19381 4-({[4-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]amino}methyl)benzonitrile::2,4-diaminopyrimidine derivative, 7g Growth hormone secretagogue receptor type 1 Homo sapiens 160 780 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19381 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19381&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11256439 46519404 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34570 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(=O)(=O)C(F)(F)F)cc1 InChI=1S/C20H20F3N5O2S/c1-2-16-17(18(24)28-19(25)27-16)13-5-7-14(8-6-13)26-11-12-3-9-15(10-4-12)31(29,30)20(21,22)23/h3-10,26H,2,11H2,1H3,(H4,24,25,27,28) GNKWFVBWMRYDNB-UHFFFAOYSA-N 19382 6-ethyl-5-[4-({[4-(trifluoromethane)sulfonylphenyl]methyl}amino)phenyl]pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 7h Growth hormone secretagogue receptor type 1 Homo sapiens 21 690 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19382 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19382&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11546904 46519405 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34571 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccnc(Cl)c2)cc1 InChI=1S/C18H19ClN6/c1-2-14-16(17(20)25-18(21)24-14)12-3-5-13(6-4-12)23-10-11-7-8-22-15(19)9-11/h3-9,23H,2,10H2,1H3,(H4,20,21,24,25) PCMWSMMFLPUBKG-UHFFFAOYSA-N 19383 5-(4-{[(2-chloropyridin-4-yl)methyl]amino}phenyl)-6-ethylpyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 7i Growth hormone secretagogue receptor type 1 Homo sapiens 110 220 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19383 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19383&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11537683 46519406 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34572 CCc1nc(N)nc(N)c1-c1ccc(NCc2csc(Cl)c2)cc1 InChI=1S/C17H18ClN5S/c1-2-13-15(16(19)23-17(20)22-13)11-3-5-12(6-4-11)21-8-10-7-14(18)24-9-10/h3-7,9,21H,2,8H2,1H3,(H4,19,20,22,23) HIKCEIZHQIIQHG-UHFFFAOYSA-N 19384 5-(4-{[(5-chlorothiophen-3-yl)methyl]amino}phenyl)-6-ethylpyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 7j Growth hormone secretagogue receptor type 1 Homo sapiens 290 790 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19384 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19384&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11617435 46519407 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34573 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(Cl)cc2)cc1 InChI=1S/C25H24ClN5O/c26-20-10-6-17(7-11-20)14-29-21-12-8-19(9-13-21)23-22(30-25(28)31-24(23)27)16-32-15-18-4-2-1-3-5-18/h1-13,29H,14-16H2,(H4,27,28,30,31) YHNPYJODGMGFSJ-UHFFFAOYSA-N 19385 6-[(benzyloxy)methyl]-5-(4-{[(4-chlorophenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::JMC494459 4b::2,4-diaminopyrimidine derivative, 8a Growth hormone secretagogue receptor type 1 Homo sapiens 19 180 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19385 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19385&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11282247 46519408 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34574 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(cc2)[N+]([O-])=O)cc1 InChI=1S/C25H24N6O3/c26-24-23(22(29-25(27)30-24)16-34-15-18-4-2-1-3-5-18)19-8-10-20(11-9-19)28-14-17-6-12-21(13-7-17)31(32)33/h1-13,28H,14-16H2,(H4,26,27,29,30) MOFWLTYYTPWVCA-UHFFFAOYSA-N 19386 6-[(benzyloxy)methyl]-5-(4-{[(4-nitrophenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8b Growth hormone secretagogue receptor type 1 Homo sapiens 0.2 5.8 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19386 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19386&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11340044 46519409 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34575 CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccccc2)cc1 InChI=1S/C26H27N5O3S/c1-35(32,33)22-13-7-18(8-14-22)15-29-21-11-9-20(10-12-21)24-23(30-26(28)31-25(24)27)17-34-16-19-5-3-2-4-6-19/h2-14,29H,15-17H2,1H3,(H4,27,28,30,31) AMXPCCCIUNIREO-UHFFFAOYSA-N 19387 CHEMBL425594::6-[(benzyloxy)methyl]-5-(4-{[(4-methanesulfonylphenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8c Growth hormone secretagogue receptor type 1 Homo sapiens 0.3 7.2 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19387 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19387&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11225576 46519410 CHEMBL425594 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34576 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(cc2)S(=O)(=O)C(F)(F)F)cc1 InChI=1S/C26H24F3N5O3S/c27-26(28,29)38(35,36)21-12-6-17(7-13-21)14-32-20-10-8-19(9-11-20)23-22(33-25(31)34-24(23)30)16-37-15-18-4-2-1-3-5-18/h1-13,32H,14-16H2,(H4,30,31,33,34) YIRVMBRTDCZPQZ-UHFFFAOYSA-N 19388 6-[(benzyloxy)methyl]-5-[4-({[4-(trifluoromethane)sulfonylphenyl]methyl}amino)phenyl]pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8d Growth hormone secretagogue receptor type 1 Homo sapiens 1.0 85 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19388 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19388&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11519554 46519411 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34577 CC(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccccc2)cc1 InChI=1S/C27H27N5O2/c1-18(33)21-9-7-19(8-10-21)15-30-23-13-11-22(12-14-23)25-24(31-27(29)32-26(25)28)17-34-16-20-5-3-2-4-6-20/h2-14,30H,15-17H2,1H3,(H4,28,29,31,32) ZHBOQUMPNGYASG-UHFFFAOYSA-N 19389 1-(4-{[(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)amino]methyl}phenyl)ethan-1-one::2,4-diaminopyrimidine derivative, 8e Growth hormone secretagogue receptor type 1 Homo sapiens 1.2 10 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19389 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19389&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11712151 46519412 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34578 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccnc(Cl)c2)cc1 InChI=1S/C24H23ClN6O/c25-21-12-17(10-11-28-21)13-29-19-8-6-18(7-9-19)22-20(30-24(27)31-23(22)26)15-32-14-16-4-2-1-3-5-16/h1-12,29H,13-15H2,(H4,26,27,30,31) HVKOXQJDFNUOSJ-UHFFFAOYSA-N 19390 6-[(benzyloxy)methyl]-5-(4-{[(2-chloropyridin-4-yl)methyl]amino}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8f Growth hormone secretagogue receptor type 1 Homo sapiens 1.5 3.6 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19390 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19390&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11339816 46519413 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34579 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(cc2)C#N)cc1 InChI=1S/C26H24N6O/c27-14-18-6-8-19(9-7-18)15-30-22-12-10-21(11-13-22)24-23(31-26(29)32-25(24)28)17-33-16-20-4-2-1-3-5-20/h1-13,30H,15-17H2,(H4,28,29,31,32) GVRGGYIFRFDABU-UHFFFAOYSA-N 19391 4-{[(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)amino]methyl}benzonitrile::2,4-diaminopyrimidine derivative, 8g Growth hormone secretagogue receptor type 1 Homo sapiens 2.8 19 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19391 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19391&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11154823 46519414 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34580 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C26H24F3N5O/c27-26(28,29)20-10-6-17(7-11-20)14-32-21-12-8-19(9-13-21)23-22(33-25(31)34-24(23)30)16-35-15-18-4-2-1-3-5-18/h1-13,32H,14-16H2,(H4,30,31,33,34) RVCXILYFOWJXDJ-UHFFFAOYSA-N 19392 6-[(benzyloxy)methyl]-5-[4-({[4-(trifluoromethyl)phenyl]methyl}amino)phenyl]pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8h Growth hormone secretagogue receptor type 1 Homo sapiens 2.9 97 7.4000 22.00 C Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19392 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19392&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11583811 46519415 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34582 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2csc(Cl)c2)cc1 InChI=1S/C23H22ClN5OS/c24-20-10-16(14-31-20)11-27-18-8-6-17(7-9-18)21-19(28-23(26)29-22(21)25)13-30-12-15-4-2-1-3-5-15/h1-10,14,27H,11-13H2,(H4,25,26,28,29) FQUNLLIRLOFAFL-UHFFFAOYSA-N 19393 6-[(benzyloxy)methyl]-5-(4-{[(5-chlorothiophen-3-yl)methyl]amino}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8i Growth hormone secretagogue receptor type 1 Homo sapiens 6.3 170 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19393 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19393&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11612155 46519416 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34583 COc1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccccc2)cc1 InChI=1S/C26H27N5O2/c1-32-22-13-7-18(8-14-22)15-29-21-11-9-20(10-12-21)24-23(30-26(28)31-25(24)27)17-33-16-19-5-3-2-4-6-19/h2-14,29H,15-17H2,1H3,(H4,27,28,30,31) MOYAAQYNFRRWSY-UHFFFAOYSA-N 19394 6-[(benzyloxy)methyl]-5-(4-{[(4-methoxyphenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8j Growth hormone secretagogue receptor type 1 Homo sapiens 7.7 90 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19394 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19394&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11453509 46519417 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34584 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccncc2)cc1 InChI=1S/C24H24N6O/c25-23-22(19-6-8-20(9-7-19)28-14-17-10-12-27-13-11-17)21(29-24(26)30-23)16-31-15-18-4-2-1-3-5-18/h1-13,28H,14-16H2,(H4,25,26,29,30) HDJPAPNEPOKPQG-UHFFFAOYSA-N 19395 6-[(benzyloxy)methyl]-5-{4-[(pyridin-4-ylmethyl)amino]phenyl}pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8k Growth hormone secretagogue receptor type 1 Homo sapiens 21 86 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19395 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19395&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11327400 46519418 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34585 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(Cl)s2)cc1 InChI=1S/C23H22ClN5OS/c24-20-11-10-18(31-20)12-27-17-8-6-16(7-9-17)21-19(28-23(26)29-22(21)25)14-30-13-15-4-2-1-3-5-15/h1-11,27H,12-14H2,(H4,25,26,28,29) ALMNUCWWJJTEKG-UHFFFAOYSA-N 19396 6-[(benzyloxy)methyl]-5-(4-{[(5-chlorothiophen-2-yl)methyl]amino}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8l Growth hormone secretagogue receptor type 1 Homo sapiens 43 320 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19396 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19396&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11655355 46519419 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34586 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccccc2)cc1 InChI=1S/C25H25N5O/c26-24-23(20-11-13-21(14-12-20)28-15-18-7-3-1-4-8-18)22(29-25(27)30-24)17-31-16-19-9-5-2-6-10-19/h1-14,28H,15-17H2,(H4,26,27,29,30) RXJCQXFHLUPFNH-UHFFFAOYSA-N 19397 5-[4-(benzylamino)phenyl]-6-[(benzyloxy)methyl]pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8m Growth hormone secretagogue receptor type 1 Homo sapiens 50 980 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19397 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19397&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11281346 46519420 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34587 CC(C)(C)CNc1ccc(cc1)-c1c(N)nc(N)nc1COCc1ccccc1 InChI=1S/C23H29N5O/c1-23(2,3)15-26-18-11-9-17(10-12-18)20-19(27-22(25)28-21(20)24)14-29-13-16-7-5-4-6-8-16/h4-12,26H,13-15H2,1-3H3,(H4,24,25,27,28) SDJASAAFMKFISE-UHFFFAOYSA-N 19398 6-[(benzyloxy)methyl]-5-{4-[(2,2-dimethylpropyl)amino]phenyl}pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8n Growth hormone secretagogue receptor type 1 Homo sapiens 67 700 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19398 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19398&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11176805 46519421 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34588 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2cnc3ccccc3c2)cc1 InChI=1S/C28H26N6O/c29-27-26(25(33-28(30)34-27)18-35-17-19-6-2-1-3-7-19)21-10-12-23(13-11-21)31-15-20-14-22-8-4-5-9-24(22)32-16-20/h1-14,16,31H,15,17-18H2,(H4,29,30,33,34) MGHLQXSUSIVMRA-UHFFFAOYSA-N 19399 6-[(benzyloxy)methyl]-5-{4-[(quinolin-3-ylmethyl)amino]phenyl}pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 8o Growth hormone secretagogue receptor type 1 Homo sapiens 130 780 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19399 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19399&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11655578 46519422 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34589 Nc1nc(N)c(c(CCc2ccccc2)n1)-c1ccc(NCc2ccc(Cl)cc2)cc1 InChI=1S/C25H24ClN5/c26-20-11-6-18(7-12-20)16-29-21-13-9-19(10-14-21)23-22(30-25(28)31-24(23)27)15-8-17-4-2-1-3-5-17/h1-7,9-14,29H,8,15-16H2,(H4,27,28,30,31) GWZJEFHVGSPENX-UHFFFAOYSA-N 19400 5-(4-{[(4-chlorophenyl)methyl]amino}phenyl)-6-(2-phenylethyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 9 Growth hormone secretagogue receptor type 1 Homo sapiens 3170 3350 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19400 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19400&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11654867 46519423 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34590 CS(=O)(=O)c1ccc(COc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccccc2)cc1 InChI=1S/C26H26N4O4S/c1-35(31,32)22-13-7-19(8-14-22)16-34-21-11-9-20(10-12-21)24-23(29-26(28)30-25(24)27)17-33-15-18-5-3-2-4-6-18/h2-14H,15-17H2,1H3,(H4,27,28,29,30) KFLKTGXRCNNVMN-UHFFFAOYSA-N 19401 6-[(benzyloxy)methyl]-5-{4-[(4-methanesulfonylphenyl)methoxy]phenyl}pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 10a Growth hormone secretagogue receptor type 1 Homo sapiens 6.9 48 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19401 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19401&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11179347 46519424 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34591 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(OCc2ccc(cc2)C#N)cc1 InChI=1S/C26H23N5O2/c27-14-18-6-8-20(9-7-18)16-33-22-12-10-21(11-13-22)24-23(30-26(29)31-25(24)28)17-32-15-19-4-2-1-3-5-19/h1-13H,15-17H2,(H4,28,29,30,31) AQYMUQIJCIMKFH-UHFFFAOYSA-N 19402 2,4-diaminopyrimidine derivative, 10b Growth hormone secretagogue receptor type 1 Homo sapiens 83 3610 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19402 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19402&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11166495 46519425 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34592 Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(CNc2ccc(cc2)[N+]([O-])=O)cc1 InChI=1S/C25H24N6O3/c26-24-23(22(29-25(27)30-24)16-34-15-18-4-2-1-3-5-18)19-8-6-17(7-9-19)14-28-20-10-12-21(13-11-20)31(32)33/h1-13,28H,14-16H2,(H4,26,27,29,30) ZYAZVTWKLXIJIM-UHFFFAOYSA-N 19403 6-[(benzyloxy)methyl]-5-(4-{[(4-nitrophenyl)amino]methyl}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 11a Growth hormone secretagogue receptor type 1 Homo sapiens 0.8 16 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19403 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19403&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11476589 46519426 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34593 CCc1nc(N)nc(N)c1-c1ccc(CNc2ccc(cc2)[N+]([O-])=O)cc1 InChI=1S/C19H20N6O2/c1-2-16-17(18(20)24-19(21)23-16)13-5-3-12(4-6-13)11-22-14-7-9-15(10-8-14)25(26)27/h3-10,22H,2,11H2,1H3,(H4,20,21,23,24) JTIPPBYRDLYHPP-UHFFFAOYSA-N 19404 6-ethyl-5-(4-{[(4-nitrophenyl)amino]methyl}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 11b Growth hormone secretagogue receptor type 1 Homo sapiens 9.2 190 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19404&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11646276 46519427 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34594 CCc1nc(N)nc(N)c1-c1ccc(CNc2ccc(cc2)S(C)(=O)=O)cc1 InChI=1S/C20H23N5O2S/c1-3-17-18(19(21)25-20(22)24-17)14-6-4-13(5-7-14)12-23-15-8-10-16(11-9-15)28(2,26)27/h4-11,23H,3,12H2,1-2H3,(H4,21,22,24,25) NREVZZLRLIFPFR-UHFFFAOYSA-N 19405 6-ethyl-5-(4-{[(4-methanesulfonylphenyl)amino]methyl}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 11c Growth hormone secretagogue receptor type 1 Homo sapiens 9.8 120 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19405 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19405&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11538534 46519428 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34595 CCc1nc(N)nc(N)c1-c1ccc(CNc2ccc(Cl)cc2)cc1 InChI=1S/C19H20ClN5/c1-2-16-17(18(21)25-19(22)24-16)13-5-3-12(4-6-13)11-23-15-9-7-14(20)8-10-15/h3-10,23H,2,11H2,1H3,(H4,21,22,24,25) DVVRFOFXTWNJKJ-UHFFFAOYSA-N 19406 5-(4-{[(4-chlorophenyl)amino]methyl}phenyl)-6-ethylpyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 11d Growth hormone secretagogue receptor type 1 Homo sapiens 300 3150 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19406 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19406&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11508639 46519429 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34596 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)c(Cl)c1 InChI=1S/C20H22ClN5O2S/c1-3-16-18(19(22)26-20(23)25-16)13-6-9-17(15(21)10-13)24-11-12-4-7-14(8-5-12)29(2,27)28/h4-10,24H,3,11H2,1-2H3,(H4,22,23,25,26) PBINSYAGPJRURP-UHFFFAOYSA-N 19407 5-(3-chloro-4-{[(4-methanesulfonylphenyl)methyl]amino}phenyl)-6-ethylpyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 12a Growth hormone secretagogue receptor type 1 Homo sapiens 4.2 11 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19407 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19407&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11430392 46519430 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34597 CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(C)(=O)=O)c(Br)c1 InChI=1S/C20H22BrN5O2S/c1-3-16-18(19(22)26-20(23)25-16)13-6-9-17(15(21)10-13)24-11-12-4-7-14(8-5-12)29(2,27)28/h4-10,24H,3,11H2,1-2H3,(H4,22,23,25,26) MQXFABSPVUDYEU-UHFFFAOYSA-N 19408 5-(3-bromo-4-{[(4-methanesulfonylphenyl)methyl]amino}phenyl)-6-ethylpyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 12b Growth hormone secretagogue receptor type 1 Homo sapiens 5.7 42 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19408 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19408&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11605333 46519431 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 34598 CCc1nc(N)nc(N)c1-c1ccc(cc1)N(C)Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C21H25N5O2S/c1-4-18-19(20(22)25-21(23)24-18)15-7-9-16(10-8-15)26(2)13-14-5-11-17(12-6-14)29(3,27)28/h5-12H,4,13H2,1-3H3,(H4,22,23,24,25) WUAICMBTLZKROR-UHFFFAOYSA-N 19409 6-ethyl-5-(4-{[(4-methanesulfonylphenyl)methyl](methyl)amino}phenyl)pyrimidine-2,4-diamine::2,4-diaminopyrimidine derivative, 13 Growth hormone secretagogue receptor type 1 Homo sapiens 3.7 32 Curated from the literature by BindingDB 10.1021/jm0510934 10.7270/Q27W69G1 16610800 aid1797847 Serby, MD; Zhao, H; Szczepankiewicz, BG; Kosogof, C; Xin, Z; Liu, B; Liu, M; Nelson, LT; Kaszubska, W; Falls, HD; Schaefer, V; Bush, EN; Shapiro, R; Droz, BA; Knourek-Segel, VE; Fey, TA; Brune, ME; Beno, DW; Turner, TM; Collins, CA; Jacobson, PB; Sham, HL; Liu, G 4/20/2006 12/10/2007 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19409 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19409&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 11690097 46519432 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39771 null InChI=1S/C149H249N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(191-135(225)103(75-197)171-115(204)73-154)137(227)187-101(71-84-32-14-13-15-33-84)133(223)186-100(70-81(4)5)132(222)190-105(77-199)144(234)194-66-29-42-108(194)139(229)180-95(51-57-117(207)208)128(218)188-102(72-85-74-165-79-169-85)134(224)179-92(47-53-112(156)201)126(216)175-90(39-26-63-167-148(161)162)130(220)192-119(82(6)7)141(231)181-93(48-54-113(157)202)127(217)177-91(46-52-111(155)200)125(215)174-89(38-25-62-166-147(159)160)122(212)173-87(35-18-22-59-151)121(211)178-94(50-56-116(205)206)129(219)189-104(76-198)136(226)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164/h13-15,32-33,74,79-83,86-110,119,197-199H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,226)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,227)(H,188,218)(H,189,219)(H,190,222)(H,191,225)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168) GNKDKYIHGQKHHM-UHFFFAOYSA-N 21940 Ghrelin::US20240190875, Example Ghrelin Growth hormone secretagogue receptor type 1 Homo sapiens 1.4 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21940 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21940&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 91895995 49701044 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39772 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NCCCCO |r| InChI=1S/C21H33N7O5/c1-21(2,22)19(30)24-17(15-32-14-16-8-4-3-5-9-16)18-25-26-27-28(18)11-13-33-20(31)23-10-6-7-12-29/h3-5,8-9,17,29H,6-7,10-15,22H2,1-2H3,(H,23,31)(H,24,30) KJXOYJXMFGXDRR-UHFFFAOYSA-N 21941 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-(4-hydroxybutyl)carbamate::BMS-317180::CHEMBL398372::Tetrazole-based compound, 2 Growth hormone secretagogue receptor type 1 Homo sapiens 1.9 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21941 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21941&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23649669 49701045 CHEMBL398372 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39773 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NCCO |r| InChI=1S/C19H29N7O5/c1-19(2,20)17(28)22-15(13-30-12-14-6-4-3-5-7-14)16-23-24-25-26(16)9-11-31-18(29)21-8-10-27/h3-7,15,27H,8-13,20H2,1-2H3,(H,21,29)(H,22,28) KUKWMQLFBQKZLK-UHFFFAOYSA-N 21942 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-(2-hydroxyethyl)carbamate::Tetrazole-based compound, 8 Growth hormone secretagogue receptor type 1 Homo sapiens 3.0 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21942 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21942&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730225 49701046 C04080 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39774 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NCCCO |r| InChI=1S/C20H31N7O5/c1-20(2,21)18(29)23-16(14-31-13-15-7-4-3-5-8-15)17-24-25-26-27(17)10-12-32-19(30)22-9-6-11-28/h3-5,7-8,16,28H,6,9-14,21H2,1-2H3,(H,22,30)(H,23,29) KNVNLNUMLDAJRC-UHFFFAOYSA-N 21943 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-(3-hydroxypropyl)carbamate::Tetrazole-based compound, 9 Growth hormone secretagogue receptor type 1 Homo sapiens 5.5 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21943 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21943&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730226 49701047 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39775 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NCCCCCO |r| InChI=1S/C22H35N7O5/c1-22(2,23)20(31)25-18(16-33-15-17-9-5-3-6-10-17)19-26-27-28-29(19)12-14-34-21(32)24-11-7-4-8-13-30/h3,5-6,9-10,18,30H,4,7-8,11-16,23H2,1-2H3,(H,24,32)(H,25,31) JLULZNCWGALFOB-UHFFFAOYSA-N 21944 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-(5-hydroxypentyl)carbamate::Tetrazole-based compound, 10 Growth hormone secretagogue receptor type 1 Homo sapiens 14.6 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21944 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21944&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730227 49701048 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39776 CN(CCCCO)C(=O)OCCn1nnnc1[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N |r| InChI=1S/C22H35N7O5/c1-22(2,23)20(31)24-18(16-33-15-17-9-5-4-6-10-17)19-25-26-27-29(19)12-14-34-21(32)28(3)11-7-8-13-30/h4-6,9-10,18,30H,7-8,11-16,23H2,1-3H3,(H,24,31) TWGBAIZTRVRIAV-UHFFFAOYSA-N 21945 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-(4-hydroxybutyl)-N-methylcarbamate::Tetrazole-based compound, 11 Growth hormone secretagogue receptor type 1 Homo sapiens 3.8 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21945 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21945&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730228 49701049 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39777 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)N1CC[C@@H](O)C1 |r| InChI=1S/C21H31N7O5/c1-21(2,22)19(30)23-17(14-32-13-15-6-4-3-5-7-15)18-24-25-26-28(18)10-11-33-20(31)27-9-8-16(29)12-27/h3-7,16-17,29H,8-14,22H2,1-2H3,(H,23,30) XFPBNXCMOFTXQF-UHFFFAOYSA-N 21946 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl (3R)-3-hydroxypyrrolidine-1-carboxylate::Tetrazole-based compound, 12 Growth hormone secretagogue receptor type 1 Homo sapiens 1.0 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21946 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21946&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 9890504 49701050 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39778 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)N1CCC(C)(O)C1 |r| InChI=1S/C22H33N7O5/c1-21(2,23)19(30)24-17(14-33-13-16-7-5-4-6-8-16)18-25-26-27-29(18)11-12-34-20(31)28-10-9-22(3,32)15-28/h4-8,17,32H,9-15,23H2,1-3H3,(H,24,30) JMCRWYGWYWGCKU-UHFFFAOYSA-N 21947 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl 3-hydroxy-3-methylpyrrolidine-1-carboxylate::Tetrazole-based compound, 13 Growth hormone secretagogue receptor type 1 Homo sapiens 10.1 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21947 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21947&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730339 49701051 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39779 CC(=O)NCCCCNC(=O)OCCn1nnnc1[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N |r| InChI=1S/C23H36N8O5/c1-17(32)25-11-7-8-12-26-22(34)36-14-13-31-20(28-29-30-31)19(27-21(33)23(2,3)24)16-35-15-18-9-5-4-6-10-18/h4-6,9-10,19H,7-8,11-16,24H2,1-3H3,(H,25,32)(H,26,34)(H,27,33) OBOLPKMJYZNIHK-UHFFFAOYSA-N 21948 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-(4-acetamidobutyl)carbamate::Tetrazole-based compound, 14 Growth hormone secretagogue receptor type 1 Homo sapiens 82.5 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21948 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21948&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730340 49701052 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39780 CC(=O)N[C@@H]1CCN(C1)C(=O)OCCn1nnnc1[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N |r| InChI=1S/C23H34N8O5/c1-16(32)25-18-9-10-30(13-18)22(34)36-12-11-31-20(27-28-29-31)19(26-21(33)23(2,3)24)15-35-14-17-7-5-4-6-8-17/h4-8,18-19H,9-15,24H2,1-3H3,(H,25,32)(H,26,33) QFFIHUHLUGLDBF-UHFFFAOYSA-N 21949 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl (3R)-3-acetamidopyrrolidine-1-carboxylate::Tetrazole-based compound, 15 Growth hormone secretagogue receptor type 1 Homo sapiens 3.3 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21949 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21949&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730341 49701053 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39781 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NCCc1cccc(O)c1 |r| InChI=1S/C25H33N7O5/c1-25(2,26)23(34)28-21(17-36-16-19-7-4-3-5-8-19)22-29-30-31-32(22)13-14-37-24(35)27-12-11-18-9-6-10-20(33)15-18/h3-10,15,21,33H,11-14,16-17,26H2,1-2H3,(H,27,35)(H,28,34) JMKGUEVCWGAJAZ-UHFFFAOYSA-N 21950 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-[2-(3-hydroxyphenyl)ethyl]carbamate::Tetrazole-based compound, 16 Growth hormone secretagogue receptor type 1 Homo sapiens 7.9 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21950 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21950&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730342 49701054 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39782 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NC[C@H]1CCCO1 |r| InChI=1S/C22H33N7O5/c1-22(2,23)20(30)25-18(15-32-14-16-7-4-3-5-8-16)19-26-27-28-29(19)10-12-34-21(31)24-13-17-9-6-11-33-17/h3-5,7-8,17-18H,6,9-15,23H2,1-2H3,(H,24,31)(H,25,30) KRYODFPOSXJCNG-UHFFFAOYSA-N 21951 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-[(2R)-oxolan-2-ylmethyl]carbamate::Tetrazole-based compound, 17 Growth hormone secretagogue receptor type 1 Homo sapiens 9.5 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21951 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21951&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730343 49701055 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 39783 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NCCCn1ccnc1 |r| InChI=1S/C23H33N9O4/c1-23(2,24)21(33)27-19(16-35-15-18-7-4-3-5-8-18)20-28-29-30-32(20)13-14-36-22(34)26-9-6-11-31-12-10-25-17-31/h3-5,7-8,10,12,17,19H,6,9,11,13-16,24H2,1-2H3,(H,26,34)(H,27,33) GQUGRYHPMIRJEI-UHFFFAOYSA-N 21952 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-[3-(1H-imidazol-1-yl)propyl]carbamate::Tetrazole-based compound, 18 Growth hormone secretagogue receptor type 1 Homo sapiens 45.3 7.2000 22.00 C Curated from the literature by BindingDB 10.1021/jm7010595 10.7270/Q24J0CCV 17973363 aid1798143 Li, J; Chen, SY; Li, JJ; Wang, H; Hernandez, AS; Tao, S; Musial, CM; Qu, F; Swartz, S; Chao, ST; Flynn, N; Murphy, BJ; Slusarchyk, DA; Seethala, R; Yan, M; Sleph, P; Grover, G; Smith, MA; Beehler, B; Giupponi, L; Dickinson, KE; Zhang, H; Humphreys, WG; Patel, BP; Schwinden, M; Stouch, T; Cheng, PT; Biller, SA; Ewing, WR; Gordon, D; Robl, JA; Tino, JA 11/29/2007 4/30/2008 Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21952 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21952&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 23730458 49701056 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220616 COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)[C@@H](Cc2c[nH]c3ccccc23)NC(C)=O)cc1 |r| InChI=1S/C38H36N8O3/c1-24(47)42-34(19-26-21-40-31-11-5-3-9-29(26)31)36-44-45-37(46(36)23-25-14-16-28(49-2)17-15-25)35(43-38(48)33-13-7-8-18-39-33)20-27-22-41-32-12-6-4-10-30(27)32/h3-18,21-22,34-35,40-41H,19-20,23H2,1-2H3,(H,42,47)(H,43,48) LDYITYSXTZVFHS-UHFFFAOYSA-N 102975 US8546435, 3 Growth hormone secretagogue receptor type 1 Homo sapiens 0.6 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102975 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102975&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 66788278 172098266 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220617 COc1ccc(Cn2c(nnc2[C@@H](Cc2ccccc2)NC(C)=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)cc1 |r| InChI=1S/C36H35N7O3/c1-24(44)39-32(20-25-10-4-3-5-11-25)34-41-42-35(43(34)23-26-15-17-28(46-2)18-16-26)33(40-36(45)31-14-8-9-19-37-31)21-27-22-38-30-13-7-6-12-29(27)30/h3-19,22,32-33,38H,20-21,23H2,1-2H3,(H,39,44)(H,40,45) LFNRSBOROBEJIW-UHFFFAOYSA-N 102976 US8546435, 4 Growth hormone secretagogue receptor type 1 Homo sapiens 1.3 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102976 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102976&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 56942098 172098267 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220618 COc1ccc(Cn2c(nnc2[C@@H](Cc2ccccc2)NC(C)=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CO)cc1 |r| InChI=1S/C32H34N6O4/c1-21(40)34-28(16-22-8-4-3-5-9-22)31-36-37-32(38(31)19-23-12-14-25(42-2)15-13-23)29(35-30(41)20-39)17-24-18-33-27-11-7-6-10-26(24)27/h3-15,18,28-29,33,39H,16-17,19-20H2,1-2H3,(H,34,40)(H,35,41) HQOQKRHTKLWNAZ-UHFFFAOYSA-N 102978 US8546435, 6 Growth hormone secretagogue receptor type 1 Homo sapiens 3.0 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102978 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102978&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 56942242 172098269 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220619 COc1ccc(Cn2c(nnc2[C@@H](Cc2ccccc2)NC=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)cc1 |r| InChI=1S/C35H33N7O3/c1-45-27-16-14-25(15-17-27)22-42-33(31(38-23-43)19-24-9-3-2-4-10-24)40-41-34(42)32(39-35(44)30-13-7-8-18-36-30)20-26-21-37-29-12-6-5-11-28(26)29/h2-18,21,23,31-32,37H,19-20,22H2,1H3,(H,38,43)(H,39,44) YSSONUCZBHLAKQ-UHFFFAOYSA-N 102977 US8546435, 5 Growth hormone secretagogue receptor type 1 Homo sapiens 3.4 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102977 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102977&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 56942099 172098268 C06049 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220620 COc1ccc(Cn2c(nnc2[C@@H](Cc2ccccc2)NC(C)=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CNCCO2)cc1 |r| InChI=1S/C35H39N7O4/c1-23(43)38-30(18-24-8-4-3-5-9-24)33-40-41-34(42(33)22-25-12-14-27(45-2)15-13-25)31(39-35(44)32-21-36-16-17-46-32)19-26-20-37-29-11-7-6-10-28(26)29/h3-15,20,30-32,36-37H,16-19,21-22H2,1-2H3,(H,38,43)(H,39,44) ZEWOKKRACQOIMW-UHFFFAOYSA-N 102979 US8546435, 7 Growth hormone secretagogue receptor type 1 Homo sapiens 3.4 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102979 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102979&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 56942243 172098270 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220621 COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)OCC(C)C)cc1 |r| InChI=1S/C33H37N5O3/c1-23(2)22-41-33(39)35-30(19-26-20-34-29-12-8-7-11-28(26)29)32-37-36-31(18-15-24-9-5-4-6-10-24)38(32)21-25-13-16-27(40-3)17-14-25/h4-14,16-17,20,23,30,34H,15,18-19,21-22H2,1-3H3,(H,35,39) MRZCHZFDAHUKQC-UHFFFAOYSA-N 102983 US8546435, 17 Growth hormone secretagogue receptor type 1 Homo sapiens 8.6 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102983 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102983&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 56942537 172098274 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220622 COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@@H](Cc2c[nH]c3ccccc23)NC(C)=O)cc1 |r| InChI=1S/C36H40N8O3/c1-22(45)40-31(17-24-19-38-29-11-7-5-9-27(24)29)33-42-43-34(44(33)21-23-13-15-26(47-4)16-14-23)32(41-35(46)36(2,3)37)18-25-20-39-30-12-8-6-10-28(25)30/h5-16,19-20,31-32,38-39H,17-18,21,37H2,1-4H3,(H,40,45)(H,41,46) OMEYXMRIYJZPAD-UHFFFAOYSA-N 102980 US8546435, 8 Growth hormone secretagogue receptor type 1 Homo sapiens 1.4 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102980 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102980&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 56942244 172098271 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220623 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2ccc3ccccc3c2)NC(=O)OC(C)(C)C)cc1 |r| InChI=1S/C37H39N5O3/c1-37(2,3)45-36(43)39-33(22-26-13-16-27-9-5-6-10-28(27)21-26)35-41-40-34(42(35)24-25-14-18-30(44-4)19-15-25)20-17-29-23-38-32-12-8-7-11-31(29)32/h5-16,18-19,21,23,33,38H,17,20,22,24H2,1-4H3,(H,39,43) VEVHPICPKWRYDQ-UHFFFAOYSA-N 102982 US8546435, 15 Growth hormone secretagogue receptor type 1 Homo sapiens 16.5 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102982 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102982&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 56942855 172098273 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 220624 COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@@H](Cc2c[nH]c3ccccc23)NC=O)cc1 |r| InChI=1S/C35H38N8O3/c1-35(2,36)34(45)40-31(17-24-19-38-29-11-7-5-9-27(24)29)33-42-41-32(43(33)20-22-12-14-25(46-3)15-13-22)30(39-21-44)16-23-18-37-28-10-6-4-8-26(23)28/h4-15,18-19,21,30-31,37-38H,16-17,20,36H2,1-3H3,(H,39,44)(H,40,45) DEQOTWGMVLLXTM-UHFFFAOYSA-N 102981 US8546435, 9 Growth hormone secretagogue receptor type 1 Homo sapiens 3.2 US Patent 10.7270/Q22N50XS aid1800049 US8546435 Aicher, B; Mueller, G; Paulini, K; Blumenstein, L; Schmidt, P; Gerlach, M; Teifel, M; Martinez, J; Fehrentz, J; Blayo, A 10/1/2013 12/3/2013 Aeterna Zentaris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102981 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102981&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 56942385 172098272 C06049 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 374002 CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1 InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1 UMUPQWIGCOZEOY-JOCHJYFZSA-N 50049478 1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-dihydrospiro[indole-3,4'-piperidine]-1'-yl}-1-oxopropan-2-yl]carbamoyl}-1-methylethan-1-aminium::1N-[1-benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-2-oxo-(1R)-ethyl]-2-amino-2-methylpropanamide::1N-[1-benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-2-oxo-(1R)-ethyl]-2-amino-2-methylpropanamide [3a(MK-0677)]::1N-[1-benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-2-oxo-(1R)-ethyl]-2-amino-2-methylpropanamide(MK-0677)::CHEMBL13817::MK 0677::MK-0677::MK-677 Growth hormone secretagogue receptor type 1 Homo sapiens 65.8 Curated from the literature by BindingDB 10.1074/jbc.M113.453423 10.7270/Q2F18XKT 23839942 aid1802374 Mary, S; Fehrentz, JA; Damian, M; Gaibelet, G; Orcel, H; Verdié, P; Mouillac, B; Martinez, J; Marie, J; Banères, JL 8/23/2013 2/9/2017 Université Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049478&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 1KD 7NA8 178024 103979794 CHEMBL13817 1097 ZINC01543181 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F83,7F9Y,7F9Z,7W2Z Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 374006 COc1ccc(Cn2c(CCc3ccccc3)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)c(OC)c1 InChI=1S/C35H34N6O3/c1-43-27-17-16-25(32(21-27)44-2)23-41-33(18-15-24-10-4-3-5-11-24)39-40-34(41)31(38-35(42)30-14-8-9-19-36-30)20-26-22-37-29-13-7-6-12-28(26)29/h3-14,16-17,19,21-22,31,37H,15,18,20,23H2,1-2H3,(H,38,42) UMGBPWZCCHVQAY-UHFFFAOYSA-N 212436 JMV 3002::N-[1-[4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenylethyl)-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]pyridine-2-carboxamide Growth hormone secretagogue receptor type 1 Homo sapiens 9.2 Curated from the literature by BindingDB 10.1074/jbc.M113.453423 10.7270/Q2F18XKT 23839942 aid1802374 Mary, S; Fehrentz, JA; Damian, M; Gaibelet, G; Orcel, H; Verdié, P; Mouillac, B; Martinez, J; Marie, J; Banères, JL 8/23/2013 2/9/2017 Université Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=212436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=212436&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 53394052 329588284 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F83,7F9Y,7F9Z,7W2Z Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 374011 COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)c(OC)c1 InChI=1S/C37H35N7O3/c1-46-27-16-14-25(34(20-27)47-2)23-44-35(17-15-24-21-39-30-11-5-3-9-28(24)30)42-43-36(44)33(41-37(45)32-13-7-8-18-38-32)19-26-22-40-31-12-6-4-10-29(26)31/h3-14,16,18,20-22,33,39-40H,15,17,19,23H2,1-2H3,(H,41,45) LODGFBNUXGQQQE-UHFFFAOYSA-N 212437 JMV 3011 Growth hormone secretagogue receptor type 1 Homo sapiens 8.3 Curated from the literature by BindingDB 10.1074/jbc.M113.453423 10.7270/Q2F18XKT 23839942 aid1802374 Mary, S; Fehrentz, JA; Damian, M; Gaibelet, G; Orcel, H; Verdié, P; Mouillac, B; Martinez, J; Marie, J; Banères, JL 8/23/2013 2/9/2017 Université Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=212437 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=212437&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 68741723 329588285 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 374016 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)CCCN=C(N)N)C(N)=O InChI=1S/C81H110N20O12/c1-46(2)37-61(70(85)103)94-72(105)62(38-47(3)4)95-75(108)65(41-50-44-90-57-26-12-9-22-53(50)57)98-73(106)63(39-48-19-6-5-7-20-48)96-76(109)64(40-49-43-89-56-25-11-8-21-52(49)56)97-71(104)59(31-32-69(84)102)92-74(107)66(42-51-45-91-58-27-13-10-23-54(51)58)99-78(111)68-30-18-36-101(68)80(113)60(28-14-15-33-82)93-77(110)67-29-17-35-100(67)79(112)55(83)24-16-34-88-81(86)87/h5-13,19-23,25-27,43-47,55,59-68,89-91H,14-18,24,28-42,82-83H2,1-4H3,(H2,84,102)(H2,85,103)(H,92,107)(H,93,110)(H,94,105)(H,95,108)(H,96,109)(H,97,104)(H,98,106)(H,99,111)(H4,86,87,88)/t55-,59+,60+,61+,62+,63+,64-,65-,66-,67+,68+/m1/s1 QDZOEBFLNHCSSF-PFFBOGFISA-N 212438 SPA::Substance P [DArg1, DTrp5,7,9, Leu11] Growth hormone secretagogue receptor type 1 Homo sapiens 293.7 Curated from the literature by BindingDB 10.1074/jbc.M113.453423 10.7270/Q2F18XKT 23839942 aid1802374 Mary, S; Fehrentz, JA; Damian, M; Gaibelet, G; Orcel, H; Verdié, P; Mouillac, B; Martinez, J; Marie, J; Banères, JL 8/23/2013 2/9/2017 Université Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=212438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=212438&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 124081652 329588286 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F83,7F9Y,7F9Z,7W2Z Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 1413900 NC(=O)C1(CCNCC1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)CC12CC3CC(CC(N)(C3)C1)C2 |r,TLB:51:52:55:58.60.57,60:58:62:55.54.53,60:54:62:58.61.57,59:58:55:62.52.53,THB:61:58:55:62.52.53,61:52:55:58.60.57| InChI=1S/C49H58N8O5S/c50-46(62)49(14-16-52-17-15-49)57-45(61)38(19-30-8-2-1-3-9-30)55-44(60)40(20-33-27-53-37-12-6-4-10-35(33)37)56-43(59)39(21-34-28-63-41-13-7-5-11-36(34)41)54-42(58)26-47-22-31-18-32(23-47)25-48(51,24-31)29-47/h1-13,27-28,31-32,38-40,52-53H,14-26,29,51H2,(H2,50,62)(H,54,58)(H,55,60)(H,56,59)(H,57,61) ORGDQOHUKYTNHW-UHFFFAOYSA-N 675468 US20240158438, SEQ ID NO. 28 Growth hormone secretagogue receptor type 1 Homo sapiens 54.1 US Patent 10.7270/Q2930ZHR aid1963733 US20240158438 MENG, G; FU, X; LI, S; MA, H; ZHANG, Y; LIU, S; XU, M; GAO, J; LI, Y 5/16/2024 8/19/2024 Chengdu Sintanovo Biotechnology Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=675468 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=675468&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 171919025 497644802 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 1413901 NC(=O)C1(CCNCC1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)C1N[C@@H]2CC[C@H]1C2 |r,THB:49:51:54.55:57| InChI=1S/C44H50N8O5S/c45-43(57)44(16-18-46-19-17-44)52-41(55)34(20-26-8-2-1-3-9-26)49-39(53)35(22-28-24-47-33-12-6-4-10-31(28)33)50-40(54)36(23-29-25-58-37-13-7-5-11-32(29)37)51-42(56)38-27-14-15-30(21-27)48-38/h1-13,24-25,27,30,34-36,38,46-48H,14-23H2,(H2,45,57)(H,49,53)(H,50,54)(H,51,56)(H,52,55) GEAHKQLDORGVFR-UHFFFAOYSA-N 675469 US20240158438, SEQ ID NO. 29 Growth hormone secretagogue receptor type 1 Homo sapiens 13.3 US Patent 10.7270/Q2930ZHR aid1963733 US20240158438 MENG, G; FU, X; LI, S; MA, H; ZHANG, Y; LIU, S; XU, M; GAO, J; LI, Y 5/16/2024 8/19/2024 Chengdu Sintanovo Biotechnology Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=675469 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=675469&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 171919026 497644803 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 1413930 NCCCC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)CC12CC3CC(CC(N)(C3)C1)C2)C(N)=O |r,TLB:48:49:52:55.57.54,57:55:59:52.51.50,57:51:59:55.58.54,56:55:52:59.49.50,THB:58:55:52:59.49.50,58:49:52:55.57.54| InChI=1S/C49H60N8O5S/c50-17-9-8-15-38(44(51)59)55-45(60)39(19-30-10-2-1-3-11-30)56-47(62)41(20-33-27-53-37-14-6-4-12-35(33)37)57-46(61)40(21-34-28-63-42-16-7-5-13-36(34)42)54-43(58)26-48-22-31-18-32(23-48)25-49(52,24-31)29-48/h1-7,10-14,16,27-28,31-32,38-41,53H,8-9,15,17-26,29,50,52H2,(H2,51,59)(H,54,58)(H,55,60)(H,56,62)(H,57,61) FPOJHYJIDBGXLD-UHFFFAOYSA-N 675498 US20240158438, SEQ ID NO. 58 Growth hormone secretagogue receptor type 1 Homo sapiens 104 US Patent 10.7270/Q2930ZHR aid1963733 US20240158438 MENG, G; FU, X; LI, S; MA, H; ZHANG, Y; LIU, S; XU, M; GAO, J; LI, Y 5/16/2024 8/19/2024 Chengdu Sintanovo Biotechnology Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=675498 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=675498&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 171919055 497644832 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 1413931 NCCCC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)C1N[C@@H]2CC[C@H]1C2)C(N)=O |r,THB:46:48:51.52:54| InChI=1S/C44H52N8O5S/c45-19-9-8-15-34(40(46)53)49-41(54)35(20-26-10-2-1-3-11-26)50-42(55)36(22-28-24-47-33-14-6-4-12-31(28)33)51-43(56)37(23-29-25-58-38-16-7-5-13-32(29)38)52-44(57)39-27-17-18-30(21-27)48-39/h1-7,10-14,16,24-25,27,30,34-37,39,47-48H,8-9,15,17-23,45H2,(H2,46,53)(H,49,54)(H,50,55)(H,51,56)(H,52,57) CBUMYFKRXJZNOS-UHFFFAOYSA-N 675499 US20240158438, SEQ ID NO. 59 Growth hormone secretagogue receptor type 1 Homo sapiens 16.8 US Patent 10.7270/Q2930ZHR aid1963733 US20240158438 MENG, G; FU, X; LI, S; MA, H; ZHANG, Y; LIU, S; XU, M; GAO, J; LI, Y 5/16/2024 8/19/2024 Chengdu Sintanovo Biotechnology Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=675499 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=675499&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 171919056 497644833 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 1413940 NC(=N)NCCC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)CC12CC3CC(CC(N)(C3)C1)C2)C(N)=O |r,TLB:50:51:54:57.59.56,59:57:61:54.53.52,59:53:61:57.60.56,58:57:54:61.51.52,THB:60:57:54:61.51.52,60:51:54:57.59.56| InChI=1S/C49H60N10O5S/c50-43(61)37(14-8-16-54-47(51)52)57-44(62)38(18-29-9-2-1-3-10-29)58-46(64)40(19-32-26-55-36-13-6-4-11-34(32)36)59-45(63)39(20-33-27-65-41-15-7-5-12-35(33)41)56-42(60)25-48-21-30-17-31(22-48)24-49(53,23-30)28-48/h1-7,9-13,15,26-27,30-31,37-40,55H,8,14,16-25,28,53H2,(H2,50,61)(H,56,60)(H,57,62)(H,58,64)(H,59,63)(H4,51,52,54) VDNBBVXHPQTWPF-UHFFFAOYSA-N 675508 US20240158438, SEQ ID NO. 68 Growth hormone secretagogue receptor type 1 Homo sapiens 330 US Patent 10.7270/Q2930ZHR aid1963733 US20240158438 MENG, G; FU, X; LI, S; MA, H; ZHANG, Y; LIU, S; XU, M; GAO, J; LI, Y 5/16/2024 8/19/2024 Chengdu Sintanovo Biotechnology Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=675508 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=675508&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 171919065 497644842 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 1413941 NC(=N)NCCC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)C1N[C@@H]2CC[C@H]1C2)C(N)=O |r,THB:48:50:53.54:56| InChI=1S/C44H52N10O5S/c45-39(55)33(14-8-18-48-44(46)47)51-40(56)34(19-25-9-2-1-3-10-25)52-41(57)35(21-27-23-49-32-13-6-4-11-30(27)32)53-42(58)36(22-28-24-60-37-15-7-5-12-31(28)37)54-43(59)38-26-16-17-29(20-26)50-38/h1-7,9-13,15,23-24,26,29,33-36,38,49-50H,8,14,16-22H2,(H2,45,55)(H,51,56)(H,52,57)(H,53,58)(H,54,59)(H4,46,47,48) GYAJXLUCHMOSOL-UHFFFAOYSA-N 675509 US20240158438, SEQ ID NO. 69 Growth hormone secretagogue receptor type 1 Homo sapiens 40.2 US Patent 10.7270/Q2930ZHR aid1963733 US20240158438 MENG, G; FU, X; LI, S; MA, H; ZHANG, Y; LIU, S; XU, M; GAO, J; LI, Y 5/16/2024 8/19/2024 Chengdu Sintanovo Biotechnology Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=675509 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=675509&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 171919066 497644843 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 1413950 NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)CC12CC3CC(CC(N)(C3)C1)C2 |r,TLB:42:43:46:49.51.48,51:49:53:46.45.44,51:45:53:49.52.48,50:49:46:53.43.44,THB:52:49:46:53.43.44,52:43:46:49.51.48| InChI=1S/C43H48N6O4S/c44-39(51)34(15-26-8-2-1-3-9-26)48-41(53)36(16-29-23-46-33-12-6-4-10-31(29)33)49-40(52)35(17-30-24-54-37-13-7-5-11-32(30)37)47-38(50)22-42-18-27-14-28(19-42)21-43(45,20-27)25-42/h1-13,23-24,27-28,34-36,46H,14-22,25,45H2,(H2,44,51)(H,47,50)(H,48,53)(H,49,52) JQFKOKPMVWOMTG-UHFFFAOYSA-N 675518 US20240158438, SEQ ID NO. 78 Growth hormone secretagogue receptor type 1 Homo sapiens 78.4 US Patent 10.7270/Q2930ZHR aid1963733 US20240158438 MENG, G; FU, X; LI, S; MA, H; ZHANG, Y; LIU, S; XU, M; GAO, J; LI, Y 5/16/2024 8/19/2024 Chengdu Sintanovo Biotechnology Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=675518 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=675518&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 171919075 497644852 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 1413951 NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)C1N[C@@H]2CC[C@H]1C2 |r,THB:40:42:45.46:48| InChI=1S/C38H40N6O4S/c39-35(45)30(16-22-8-2-1-3-9-22)42-36(46)31(18-24-20-40-29-12-6-4-10-27(24)29)43-37(47)32(19-25-21-49-33-13-7-5-11-28(25)33)44-38(48)34-23-14-15-26(17-23)41-34/h1-13,20-21,23,26,30-32,34,40-41H,14-19H2,(H2,39,45)(H,42,46)(H,43,47)(H,44,48) VDIJHWIHXHTFAG-UHFFFAOYSA-N 675519 US20240158438, SEQ ID NO. 79 Growth hormone secretagogue receptor type 1 Homo sapiens 33.1 US Patent 10.7270/Q2930ZHR aid1963733 US20240158438 MENG, G; FU, X; LI, S; MA, H; ZHANG, Y; LIU, S; XU, M; GAO, J; LI, Y 5/16/2024 8/19/2024 Chengdu Sintanovo Biotechnology Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=675519 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=675519&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 171919076 497644853 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7 50335677 CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2C2CC3CCC2C3)cc1 |THB:23:24:30:28.27| InChI=1S/C25H29N5O2S/c1-33(31,32)20-10-3-15(4-11-20)14-28-19-8-6-17(7-9-19)22-23(29-25(27)30-24(22)26)21-13-16-2-5-18(21)12-16/h3-4,6-11,16,18,21,28H,2,5,12-14H2,1H3,(H4,26,27,29,30) YPUKHYLHEUJWGC-UHFFFAOYSA-N 50181230 5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(bicyclo[2.2.1]heptan-2-yl)pyrimidine-2,4-diamine::CHEMBL203019 Growth hormone secretagogue receptor type 1 Homo sapiens 137 ChEMBL 10.1016/j.bmcl.2006.01.012 10.7270/Q2610ZW2 16442284 Liu, B; Liu, M; Xin, Z; Zhao, H; Serby, MD; Kosogof, C; Nelson, LT; Szczepankiewicz, BG; Kaszubska, W; Schaefer, VG; Falls, HD; Lin, CW; Collins, CA; Sham, HL; Liu, G 2/27/2006 11/10/2009 Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181230 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1991&target=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181230&enzyme=Growth+hormone+secretagogue+receptor+type+1&column=ki&startPg=0&Increment=50&submit=Search 44409611 104066072 CHEMBL203019 1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 7F9Z,7F9Y,9V2N,9UY3,8JSR,7W2Z,7F83 Growth hormone secretagogue receptor type 1 GHSR_HUMAN Q92847 Q14D12 Q6ISR8 Q92848 Q96RJ7