BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 1560561 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O12/c1-19-13-22(14-20(2)26(19)42)29(44)35-16-24(41)27(43)28-25(36-21(3)39)23(40)15-34(49-28,30(45)46)8-10-38-11-12-48-18-33(38)7-9-37(17-33)31(47)50-32(4,5)6/h13-14,23-25,27-28,40-43H,7-12,15-18H2,1-6H3,(H,35,44)(H,36,39)(H,45,46) RSKQNKDGYWUMNO-UHFFFAOYSA-N 778144 US20250313574, Example A-001 Myeloid cell surface antigen CD33 15.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778144 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778144&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292901 523296491 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560562 COC(=O)[C@@]1(CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O1 InChI=1S/C35H54N4O12/c1-20-14-23(15-21(2)27(20)43)30(45)36-17-25(42)28(44)29-26(37-22(3)40)24(41)16-35(50-29,31(46)48-7)9-11-39-12-13-49-19-34(39)8-10-38(18-34)32(47)51-33(4,5)6/h14-15,24-26,28-29,41-44H,8-13,16-19H2,1-7H3,(H,36,45)(H,37,40) ZYUMIDKGBSMBRA-UHFFFAOYSA-N 778145 US20250313574, Example A-002 Myeloid cell surface antigen CD33 49000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778145 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778145&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292754 523296492 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560563 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O12/c1-19-13-22(14-20(2)26(19)42)29(44)35-16-24(41)27(43)28-25(36-21(3)39)23(40)15-34(49-28,30(45)46)8-10-38-11-12-48-18-33(38)7-9-37(17-33)31(47)50-32(4,5)6/h13-14,23-25,27-28,40-43H,7-12,15-18H2,1-6H3,(H,35,44)(H,36,39)(H,45,46) RSKQNKDGYWUMNO-UHFFFAOYSA-N 778146 US20250313574, Example A-003 Myeloid cell surface antigen CD33 1140 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778146 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778146&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893293 523296493 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560564 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2C[C@@H](C)OC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O12/c1-19-12-23(13-20(2)27(19)43)30(45)36-15-25(42)28(44)29-26(37-22(4)40)24(41)14-35(50-29,31(46)47)9-11-39-16-21(3)49-18-34(39)8-10-38(17-34)32(48)51-33(5,6)7/h12-13,21,24-26,28-29,41-44H,8-11,14-18H2,1-7H3,(H,36,45)(H,37,40)(H,46,47) DWXGNSWIRTUVBI-UHFFFAOYSA-N 778147 US20250313574, Example A-004 Myeloid cell surface antigen CD33 98.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778147 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778147&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893294 523296494 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560565 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2C[C@H](C)OC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O12/c1-19-12-23(13-20(2)27(19)43)30(45)36-15-25(42)28(44)29-26(37-22(4)40)24(41)14-35(50-29,31(46)47)9-11-39-16-21(3)49-18-34(39)8-10-38(17-34)32(48)51-33(5,6)7/h12-13,21,24-26,28-29,41-44H,8-11,14-18H2,1-7H3,(H,36,45)(H,37,40)(H,46,47) DWXGNSWIRTUVBI-UHFFFAOYSA-N 778148 US20250313574, Example A-005 Myeloid cell surface antigen CD33 7.00 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778148 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778148&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893295 523296495 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560566 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOCC23CCN(C(=O)OC(C)(C)C)CC3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O12/c1-20-15-23(16-21(2)27(20)43)30(45)36-18-25(42)28(44)29-26(37-22(3)40)24(41)17-35(50-29,31(46)47)9-12-39-13-14-49-19-34(39)7-10-38(11-8-34)32(48)51-33(4,5)6/h15-16,24-26,28-29,41-44H,7-14,17-19H2,1-6H3,(H,36,45)(H,37,40)(H,46,47) GTJNEIPBVFKIEJ-UHFFFAOYSA-N 778149 US20250313574, Example A-007 Myeloid cell surface antigen CD33 811 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778149 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778149&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893296 523296496 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560567 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOCC23CN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O12/c1-18-11-21(12-19(2)25(18)41)28(43)34-14-23(40)26(42)27-24(35-20(3)38)22(39)13-33(48-27,29(44)45)7-8-37-9-10-47-17-32(37)15-36(16-32)30(46)49-31(4,5)6/h11-12,22-24,26-27,39-42H,7-10,13-17H2,1-6H3,(H,34,43)(H,35,38)(H,44,45) FYUQJCOXRDSIAL-UHFFFAOYSA-N 778150 US20250313574, Example A-008 Myeloid cell surface antigen CD33 538 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778150 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778150&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893297 523296497 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560568 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOCC2(C)CNC(=O)OC(C)(C)C)(C(=O)O)C[C@@H]1O InChI=1S/C33H52N4O12/c1-18-12-21(13-19(2)25(18)41)28(43)34-15-23(40)26(42)27-24(36-20(3)38)22(39)14-33(48-27,29(44)45)8-9-37-10-11-47-17-32(37,7)16-35-30(46)49-31(4,5)6/h12-13,22-24,26-27,39-42H,8-11,14-17H2,1-7H3,(H,34,43)(H,35,46)(H,36,38)(H,44,45) UHVVHTIOKRPHDY-UHFFFAOYSA-N 778151 US20250313574, Example A-009 Myeloid cell surface antigen CD33 2000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778151 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778151&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893298 523296498 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560569 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCN(C)C[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H55N5O11/c1-20-14-23(15-21(2)27(20)44)30(46)36-17-25(43)28(45)29-26(37-22(3)41)24(42)16-35(50-29,31(47)48)9-11-40-13-12-38(7)18-34(40)8-10-39(19-34)32(49)51-33(4,5)6/h14-15,24-26,28-29,42-45H,8-13,16-19H2,1-7H3,(H,36,46)(H,37,41)(H,47,48) RMCHRXIETQVNFG-UHFFFAOYSA-N 778152 US20250313574, Example A-010 Myeloid cell surface antigen CD33 15.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778152 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778152&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893299 523296499 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560570 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCN(C)C[C@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H55N5O11/c1-20-14-23(15-21(2)27(20)44)30(46)36-17-25(43)28(45)29-26(37-22(3)41)24(42)16-35(50-29,31(47)48)9-11-40-13-12-38(7)18-34(40)8-10-39(19-34)32(49)51-33(4,5)6/h14-15,24-26,28-29,42-45H,8-13,16-19H2,1-7H3,(H,36,46)(H,37,41)(H,47,48) RMCHRXIETQVNFG-UHFFFAOYSA-N 778153 US20250313574, Example A-011 Myeloid cell surface antigen CD33 1630 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778153 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778153&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893300 523296500 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560571 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCNC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H53N5O11/c1-19-13-22(14-20(2)26(19)43)29(45)36-16-24(42)27(44)28-25(37-21(3)40)23(41)15-34(49-28,30(46)47)8-11-39-12-9-35-17-33(39)7-10-38(18-33)31(48)50-32(4,5)6/h13-14,23-25,27-28,35,41-44H,7-12,15-18H2,1-6H3,(H,36,45)(H,37,40)(H,46,47) NBTAKJGMGAFBIF-UHFFFAOYSA-N 778154 US20250313574, Example A-012 Myeloid cell surface antigen CD33 22.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778154 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778154&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 175984739 523296501 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560572 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCNC[C@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H53N5O11/c1-19-13-22(14-20(2)26(19)43)29(45)36-16-24(42)27(44)28-25(37-21(3)40)23(41)15-34(49-28,30(46)47)8-11-39-12-9-35-17-33(39)7-10-38(18-33)31(48)50-32(4,5)6/h13-14,23-25,27-28,35,41-44H,7-12,15-18H2,1-6H3,(H,36,45)(H,37,40)(H,46,47) NBTAKJGMGAFBIF-UHFFFAOYSA-N 778155 US20250313574, Example A-013 Myeloid cell surface antigen CD33 35.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778155 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778155&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893301 523296502 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560573 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCN(C(C)=O)C[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H55N5O12/c1-20-14-24(15-21(2)28(20)46)31(48)37-17-26(45)29(47)30-27(38-22(3)42)25(44)16-36(52-30,32(49)50)9-11-41-13-12-39(23(4)43)18-35(41)8-10-40(19-35)33(51)53-34(5,6)7/h14-15,25-27,29-30,44-47H,8-13,16-19H2,1-7H3,(H,37,48)(H,38,42)(H,49,50) BVCOCDZMPUUCRJ-UHFFFAOYSA-N 778156 US20250313574, Example A-014 Myeloid cell surface antigen CD33 19.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778156 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778156&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893302 523296503 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560574 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCN(C(C)=O)C[C@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H55N5O12/c1-20-14-24(15-21(2)28(20)46)31(48)37-17-26(45)29(47)30-27(38-22(3)42)25(44)16-36(52-30,32(49)50)9-11-41-13-12-39(23(4)43)18-35(41)8-10-40(19-35)33(51)53-34(5,6)7/h14-15,25-27,29-30,44-47H,8-13,16-19H2,1-7H3,(H,37,48)(H,38,42)(H,49,50) BVCOCDZMPUUCRJ-UHFFFAOYSA-N 778157 US20250313574, Example A-015 Myeloid cell surface antigen CD33 3340 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778157 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778157&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893303 523296504 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560575 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CC(=O)N(C)C[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H53N5O12/c1-19-12-22(13-20(2)27(19)45)30(47)36-15-24(43)28(46)29-26(37-21(3)41)23(42)14-35(51-29,31(48)49)9-11-40-16-25(44)38(7)17-34(40)8-10-39(18-34)32(50)52-33(4,5)6/h12-13,23-24,26,28-29,42-43,45-46H,8-11,14-18H2,1-7H3,(H,36,47)(H,37,41)(H,48,49) WHTXCXADUBHJOU-UHFFFAOYSA-N 778158 US20250313574, Example A-016 Myeloid cell surface antigen CD33 34.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778158 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778158&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893304 523296505 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560576 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCCC23CN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O11/c1-18-12-21(13-19(2)25(18)41)28(43)34-15-23(40)26(42)27-24(35-20(3)38)22(39)14-33(47-27,29(44)45)9-11-37-10-7-8-32(37)16-36(17-32)30(46)48-31(4,5)6/h12-13,22-24,26-27,39-42H,7-11,14-17H2,1-6H3,(H,34,43)(H,35,38)(H,44,45) JRNUFLQOESLTSY-UHFFFAOYSA-N 778159 US20250313574, Example A-017 Myeloid cell surface antigen CD33 1560 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778159 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778159&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893305 523296506 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560577 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O11/c1-18-13-21(14-19(2)25(18)41)28(43)34-16-23(40)26(42)27-24(35-20(3)38)22(39)15-33(47-27,29(44)45)9-12-37-11-8-32(37)7-10-36(17-32)30(46)48-31(4,5)6/h13-14,22-24,26-27,39-42H,7-12,15-17H2,1-6H3,(H,34,43)(H,35,38)(H,44,45) RLHIJASSTHQJFD-UHFFFAOYSA-N 778160 US20250313574, Example A-018 Myeloid cell surface antigen CD33 162 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778160 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778160&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893306 523296507 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560578 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O11/c1-19-14-22(15-20(2)26(19)42)29(44)35-17-24(41)27(43)28-25(36-21(3)39)23(40)16-34(48-28,30(45)46)10-13-38-11-7-8-33(38)9-12-37(18-33)31(47)49-32(4,5)6/h14-15,23-25,27-28,40-43H,7-13,16-18H2,1-6H3,(H,35,44)(H,36,39)(H,45,46) KDBYMGYTFUSQOJ-UHFFFAOYSA-N 778161 US20250313574, Example A-019 Myeloid cell surface antigen CD33 28.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778161 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778161&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893307 523296508 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560579 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCC[C@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O11/c1-19-14-22(15-20(2)26(19)42)29(44)35-17-24(41)27(43)28-25(36-21(3)39)23(40)16-34(48-28,30(45)46)10-13-38-11-7-8-33(38)9-12-37(18-33)31(47)49-32(4,5)6/h14-15,23-25,27-28,40-43H,7-13,16-18H2,1-6H3,(H,35,44)(H,36,39)(H,45,46) KDBYMGYTFUSQOJ-UHFFFAOYSA-N 778162 US20250313574, Example A-020 Myeloid cell surface antigen CD33 472 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778162 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778162&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893308 523296509 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560580 C=C(OC(C)(C)C)N1CC2(CCN2CC[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)C1 InChI=1S/C33H50N4O10/c1-18-12-22(13-19(2)26(18)41)29(43)34-15-24(40)27(42)28-25(35-20(3)38)23(39)14-33(47-28,30(44)45)9-11-37-10-8-32(37)16-36(17-32)21(4)46-31(5,6)7/h12-13,23-25,27-28,39-42H,4,8-11,14-17H2,1-3,5-7H3,(H,34,43)(H,35,38)(H,44,45) FSAGWEOISKOSBM-UHFFFAOYSA-N 778163 US20250313574, Example A-021 Myeloid cell surface antigen CD33 887 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778163 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778163&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893309 523296510 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560581 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCCCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O11/c1-20-15-23(16-21(2)27(20)43)30(45)36-18-25(42)28(44)29-26(37-22(3)40)24(41)17-35(49-29,31(46)47)11-14-39-12-8-7-9-34(39)10-13-38(19-34)32(48)50-33(4,5)6/h15-16,24-26,28-29,41-44H,7-14,17-19H2,1-6H3,(H,36,45)(H,37,40)(H,46,47) ORETWNSKWRLWHF-UHFFFAOYSA-N 778164 US20250313574, Example A-022 Myeloid cell surface antigen CD33 2930 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778164 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778164&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893310 523296511 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560582 C=C(OC(C)(C)C)N1CCC2(CC1)CCN2CC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O1 InChI=1S/C35H54N4O10/c1-20-16-24(17-21(2)28(20)43)31(45)36-19-26(42)29(44)30-27(37-22(3)40)25(41)18-35(49-30,32(46)47)11-15-39-14-10-34(39)8-12-38(13-9-34)23(4)48-33(5,6)7/h16-17,25-27,29-30,41-44H,4,8-15,18-19H2,1-3,5-7H3,(H,36,45)(H,37,40)(H,46,47) MXRQNQOJWLOFNX-UHFFFAOYSA-N 778165 US20250313574, Example A-023 Myeloid cell surface antigen CD33 176 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778165 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778165&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893311 523296512 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560583 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOCC2c2cccnc2)(C(=O)O)C[C@@H]1O InChI=1S/C31H42N4O10/c1-17-11-21(12-18(2)26(17)39)29(41)33-15-24(38)27(40)28-25(34-19(3)36)23(37)13-31(45-28,30(42)43)6-8-35-9-10-44-16-22(35)20-5-4-7-32-14-20/h4-5,7,11-12,14,22-25,27-28,37-40H,6,8-10,13,15-16H2,1-3H3,(H,33,41)(H,34,36)(H,42,43) YDOICPIGNHZELT-UHFFFAOYSA-N 778166 US20250313574, Example A-024 Myeloid cell surface antigen CD33 7940 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778166 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778166&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893312 523296513 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560584 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2C(C)CCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O11/c1-19-14-23(15-20(2)27(19)43)30(45)36-17-25(42)28(44)29-26(37-22(4)40)24(41)16-35(49-29,31(46)47)11-13-39-21(3)8-9-34(39)10-12-38(18-34)32(48)50-33(5,6)7/h14-15,21,24-26,28-29,41-44H,8-13,16-18H2,1-7H3,(H,36,45)(H,37,40)(H,46,47) VXWHTRRPMZVKFK-UHFFFAOYSA-N 778167 US20250313574, Example A-025 Myeloid cell surface antigen CD33 115 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778167&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893313 523296514 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560585 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCNC2(C)CCN(C(=O)OC(C)(C)C)C2)(C(=O)O)C[C@@H]1O InChI=1S/C32H50N4O11/c1-17-12-20(13-18(2)24(17)40)27(42)33-15-22(39)25(41)26-23(35-19(3)37)21(38)14-32(46-26,28(43)44)8-10-34-31(7)9-11-36(16-31)29(45)47-30(4,5)6/h12-13,21-23,25-26,34,38-41H,8-11,14-16H2,1-7H3,(H,33,42)(H,35,37)(H,43,44) JCUOHOVWFKXCAF-UHFFFAOYSA-N 778168 US20250313574, Example A-026 Myeloid cell surface antigen CD33 830 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778168 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778168&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893314 523296515 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560586 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(OCCN)c(C)c2)O[C@@](CCN2CCCC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H59N5O11/c1-22-17-25(18-23(2)30(22)51-16-12-38)32(47)39-20-27(45)29(46)31-28(40-24(3)43)26(44)19-37(52-31,33(48)49)11-15-42-13-8-7-9-36(42)10-14-41(21-36)34(50)53-35(4,5)6/h17-18,26-29,31,44-46H,7-16,19-21,38H2,1-6H3,(H,39,47)(H,40,43)(H,48,49) HDFZLVGIZBJZAQ-UHFFFAOYSA-N 778169 US20250313574, Example A-027 Myeloid cell surface antigen CD33 64.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778169 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778169&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893315 523296516 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560587 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCCC[C@]23CN(C(=O)OC(C)(C)C)C[C@@H]3CO)(C(=O)O)C[C@@H]1O InChI=1S/C36H56N4O12/c1-20-13-23(14-21(2)28(20)45)31(47)37-16-26(44)29(46)30-27(38-22(3)42)25(43)15-36(51-30,32(48)49)10-12-40-11-8-7-9-35(40)19-39(17-24(35)18-41)33(50)52-34(4,5)6/h13-14,24-27,29-30,41,43-46H,7-12,15-19H2,1-6H3,(H,37,47)(H,38,42)(H,48,49) GUEKKBSBQNNGGB-UHFFFAOYSA-N 778170 US20250313574, Example A-028 Myeloid cell surface antigen CD33 159 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778170 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778170&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292806 523296517 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560588 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCCC[C@@]23CN(C(=O)OC(C)(C)C)C[C@H]3CO)(C(=O)O)C[C@@H]1O InChI=1S/C36H56N4O12/c1-20-13-23(14-21(2)28(20)45)31(47)37-16-26(44)29(46)30-27(38-22(3)42)25(43)15-36(51-30,32(48)49)10-12-40-11-8-7-9-35(40)19-39(17-24(35)18-41)33(50)52-34(4,5)6/h13-14,24-27,29-30,41,43-46H,7-12,15-19H2,1-6H3,(H,37,47)(H,38,42)(H,48,49) GUEKKBSBQNNGGB-UHFFFAOYSA-N 778171 US20250313574, Example A-029 Myeloid cell surface antigen CD33 9730 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778171 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778171&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292834 523296518 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560589 COC[C@@]1(NCC[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)CCN(C(=O)OC(C)(C)C)C1 InChI=1S/C33H52N4O12/c1-18-12-21(13-19(2)25(18)41)28(43)34-15-23(40)26(42)27-24(36-20(3)38)22(39)14-33(48-27,29(44)45)8-10-35-32(17-47-7)9-11-37(16-32)30(46)49-31(4,5)6/h12-13,22-24,26-27,35,39-42H,8-11,14-17H2,1-7H3,(H,34,43)(H,36,38)(H,44,45) KDHNVJGLQKQVKK-UHFFFAOYSA-N 778172 US20250313574, Example A-030 Myeloid cell surface antigen CD33 49.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778172 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778172&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893316 523296519 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560590 COC[C@@]1(N(C)CC[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)CCN(C(=O)OC(C)(C)C)C1 InChI=1S/C34H54N4O12/c1-19-13-22(14-20(2)26(19)42)29(44)35-16-24(41)27(43)28-25(36-21(3)39)23(40)15-34(49-28,30(45)46)10-11-37(7)33(18-48-8)9-12-38(17-33)31(47)50-32(4,5)6/h13-14,23-25,27-28,40-43H,9-12,15-18H2,1-8H3,(H,35,44)(H,36,39)(H,45,46) CVAVPQITNHYLKH-UHFFFAOYSA-N 778173 US20250313574, Example A-031 Myeloid cell surface antigen CD33 70.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778173&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893317 523296520 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560591 C=CC[C@@]1(NCC[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)CCN(C(=O)OC(C)(C)C)C1 InChI=1S/C34H52N4O11/c1-8-9-33(11-13-38(18-33)31(47)49-32(5,6)7)36-12-10-34(30(45)46)16-23(40)25(37-21(4)39)28(48-34)27(43)24(41)17-35-29(44)22-14-19(2)26(42)20(3)15-22/h8,14-15,23-25,27-28,36,40-43H,1,9-13,16-18H2,2-7H3,(H,35,44)(H,37,39)(H,45,46) RLAPNJSIHDWKAN-UHFFFAOYSA-N 778174 US20250313574, Example A-032 Myeloid cell surface antigen CD33 181 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778174 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778174&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893318 523296521 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560592 C=CC[C@]1(NCC[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)CCN(C(=O)OC(C)(C)C)C1 InChI=1S/C34H52N4O11/c1-8-9-33(11-13-38(18-33)31(47)49-32(5,6)7)36-12-10-34(30(45)46)16-23(40)25(37-21(4)39)28(48-34)27(43)24(41)17-35-29(44)22-14-19(2)26(42)20(3)15-22/h8,14-15,23-25,27-28,36,40-43H,1,9-13,16-18H2,2-7H3,(H,35,44)(H,37,39)(H,45,46) RLAPNJSIHDWKAN-UHFFFAOYSA-N 778175 US20250313574, Example A-033 Myeloid cell surface antigen CD33 1610 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778175 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778175&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893319 523296522 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560593 C=C[C@H]1CN(C(=O)OC(C)(C)C)C[C@@]1(C)NCC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O1 InChI=1S/C34H52N4O11/c1-9-22-16-38(31(47)49-32(5,6)7)17-33(22,8)36-11-10-34(30(45)46)14-23(40)25(37-20(4)39)28(48-34)27(43)24(41)15-35-29(44)21-12-18(2)26(42)19(3)13-21/h9,12-13,22-25,27-28,36,40-43H,1,10-11,14-17H2,2-8H3,(H,35,44)(H,37,39)(H,45,46) JBTAANVGXILZFG-UHFFFAOYSA-N 778176 US20250313574, Example A-034 Myeloid cell surface antigen CD33 880 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778176 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778176&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893320 523296523 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560594 C=C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@]1(C)NCC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O1 InChI=1S/C34H52N4O11/c1-9-22-16-38(31(47)49-32(5,6)7)17-33(22,8)36-11-10-34(30(45)46)14-23(40)25(37-20(4)39)28(48-34)27(43)24(41)15-35-29(44)21-12-18(2)26(42)19(3)13-21/h9,12-13,22-25,27-28,36,40-43H,1,10-11,14-17H2,2-8H3,(H,35,44)(H,37,39)(H,45,46) JBTAANVGXILZFG-UHFFFAOYSA-N 778177 US20250313574, Example A-035 Myeloid cell surface antigen CD33 413 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778177 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778177&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893321 523296524 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560595 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(c2cc(C4CC4)ccn2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H51N5O10/c1-21-14-26(15-22(2)31(21)46)34(48)39-18-28(45)32(47)33-30(40-23(3)43)27(44)17-37(52-33,35(49)50)8-11-42-12-13-51-20-36(42)7-10-41(19-36)29-16-25(6-9-38-29)24-4-5-24/h6,9,14-16,24,27-28,30,32-33,44-47H,4-5,7-8,10-13,17-20H2,1-3H3,(H,39,48)(H,40,43)(H,49,50) PNCOXNCMYJVDLV-UHFFFAOYSA-N 778178 US20250313574, Example A-036 Myeloid cell surface antigen CD33 16.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778178 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778178&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292818 523296525 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560596 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(c2ccccn2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H47N5O10/c1-20-14-23(15-21(2)28(20)43)31(45)36-17-25(42)29(44)30-27(37-22(3)40)24(41)16-34(49-30,32(46)47)8-11-39-12-13-48-19-33(39)7-10-38(18-33)26-6-4-5-9-35-26/h4-6,9,14-15,24-25,27,29-30,41-44H,7-8,10-13,16-19H2,1-3H3,(H,36,45)(H,37,40)(H,46,47) CFWBLSCLJGKXKA-UHFFFAOYSA-N 778179 US20250313574, Example A-037 Myeloid cell surface antigen CD33 39.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778179 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778179&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893322 523296526 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560597 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(c2cc(C)ccn2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H49N5O10/c1-20-5-8-36-27(13-20)39-9-6-34(18-39)19-49-12-11-40(34)10-7-35(33(47)48)16-25(42)28(38-23(4)41)31(50-35)30(45)26(43)17-37-32(46)24-14-21(2)29(44)22(3)15-24/h5,8,13-15,25-26,28,30-31,42-45H,6-7,9-12,16-19H2,1-4H3,(H,37,46)(H,38,41)(H,47,48) HEMIIAPUWCTSPQ-UHFFFAOYSA-N 778180 US20250313574, Example A-038 Myeloid cell surface antigen CD33 53.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778180 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778180&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893323 523296527 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560598 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(c2cc(C(F)(F)F)ccn2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H46F3N5O10/c1-19-12-22(13-20(2)28(19)47)31(49)40-16-25(46)29(48)30-27(41-21(3)44)24(45)15-34(53-30,32(50)51)6-9-43-10-11-52-18-33(43)5-8-42(17-33)26-14-23(4-7-39-26)35(36,37)38/h4,7,12-14,24-25,27,29-30,45-48H,5-6,8-11,15-18H2,1-3H3,(H,40,49)(H,41,44)(H,50,51) WCDVMHOICPMTJQ-UHFFFAOYSA-N 778181 US20250313574, Example A-039 Myeloid cell surface antigen CD33 95.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778181 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778181&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893324 523296528 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560599 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(c2cnccn2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H46N6O10/c1-19-12-22(13-20(2)27(19)43)30(45)36-15-24(42)28(44)29-26(37-21(3)40)23(41)14-33(49-29,31(46)47)5-9-39-10-11-48-18-32(39)4-8-38(17-32)25-16-34-6-7-35-25/h6-7,12-13,16,23-24,26,28-29,41-44H,4-5,8-11,14-15,17-18H2,1-3H3,(H,36,45)(H,37,40)(H,46,47) XBDXNCXQGJSLEW-UHFFFAOYSA-N 778182 US20250313574, Example A-040 Myeloid cell surface antigen CD33 363 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778182 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778182&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893325 523296529 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560600 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(c2cc(N(C)C)ccn2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H52N6O10/c1-21-14-24(15-22(2)30(21)46)33(48)38-18-27(45)31(47)32-29(39-23(3)43)26(44)17-36(52-32,34(49)50)8-11-42-12-13-51-20-35(42)7-10-41(19-35)28-16-25(40(4)5)6-9-37-28/h6,9,14-16,26-27,29,31-32,44-47H,7-8,10-13,17-20H2,1-5H3,(H,38,48)(H,39,43)(H,49,50) AYSUHYSGKGCKSF-UHFFFAOYSA-N 778183 US20250313574, Example A-041 Myeloid cell surface antigen CD33 580 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778183 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778183&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893326 523296530 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560601 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H53N5O11/c1-19-13-22(14-20(2)26(19)43)29(45)35-16-24(42)27(44)28-25(36-21(3)40)23(41)15-34(50-28,30(46)47)8-10-39-11-12-49-18-33(39)7-9-38(17-33)31(48)37-32(4,5)6/h13-14,23-25,27-28,41-44H,7-12,15-18H2,1-6H3,(H,35,45)(H,36,40)(H,37,48)(H,46,47) AIKVFMVIELPECF-UHFFFAOYSA-N 778184 US20250313574, Example A-042 Myeloid cell surface antigen CD33 12.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778184 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778184&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292888 523296531 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560602 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N[C@@H](C)c2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C38H53N5O11/c1-22-16-27(17-23(2)31(22)47)34(49)39-19-29(46)32(48)33-30(41-25(4)44)28(45)18-38(54-33,35(50)51)11-13-43-14-15-53-21-37(43)10-12-42(20-37)36(52)40-24(3)26-8-6-5-7-9-26/h5-9,16-17,24,28-30,32-33,45-48H,10-15,18-21H2,1-4H3,(H,39,49)(H,40,52)(H,41,44)(H,50,51) CTRBPZOBTGUKKG-UHFFFAOYSA-N 778185 US20250313574, Example A-043 Myeloid cell surface antigen CD33 13.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778185 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778185&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893327 523296532 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560603 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC(C)C(F)(F)F)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H48F3N5O11/c1-17-11-21(12-18(2)25(17)45)28(47)37-14-23(44)26(46)27-24(39-20(4)42)22(43)13-32(52-27,29(48)49)6-8-41-9-10-51-16-31(41)5-7-40(15-31)30(50)38-19(3)33(34,35)36/h11-12,19,22-24,26-27,43-46H,5-10,13-16H2,1-4H3,(H,37,47)(H,38,50)(H,39,42)(H,48,49) BPARKVFWRLNAQP-UHFFFAOYSA-N 778186 US20250313574, Example A-044 Myeloid cell surface antigen CD33 19.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778186 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778186&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893328 523296533 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560604 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC2CCCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H55N5O11/c1-21-15-24(16-22(2)29(21)45)32(47)37-18-27(44)30(46)31-28(38-23(3)42)26(43)17-36(52-31,33(48)49)10-12-41-13-14-51-20-35(41)9-11-40(19-35)34(50)39-25-7-5-4-6-8-25/h15-16,25-28,30-31,43-46H,4-14,17-20H2,1-3H3,(H,37,47)(H,38,42)(H,39,50)(H,48,49) CODHRVNQHRPTFM-UHFFFAOYSA-N 778187 US20250313574, Example A-045 Myeloid cell surface antigen CD33 19.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778187 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778187&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893329 523296534 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560605 C=C(C)c1ccc(C(C)(C)NC(=O)N2CC[C@@]3(COCCN3CC[C@]3(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c4cc(C)c(O)c(C)c4)O3)C2)cc1 InChI=1S/C42H59N5O11/c1-24(2)28-8-10-30(11-9-28)40(6,7)45-39(56)46-14-12-41(22-46)23-57-17-16-47(41)15-13-42(38(54)55)20-31(49)33(44-27(5)48)36(58-42)35(52)32(50)21-43-37(53)29-18-25(3)34(51)26(4)19-29/h8-11,18-19,31-33,35-36,49-52H,1,12-17,20-23H2,2-7H3,(H,43,53)(H,44,48)(H,45,56)(H,54,55) BRSLHIWIJAMIRV-UHFFFAOYSA-N 778188 US20250313574, Example A-046 Myeloid cell surface antigen CD33 63.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778188 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778188&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893330 523296535 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560606 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N[C@H](C)c2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C38H53N5O11/c1-22-16-27(17-23(2)31(22)47)34(49)39-19-29(46)32(48)33-30(41-25(4)44)28(45)18-38(54-33,35(50)51)11-13-43-14-15-53-21-37(43)10-12-42(20-37)36(52)40-24(3)26-8-6-5-7-9-26/h5-9,16-17,24,28-30,32-33,45-48H,10-15,18-21H2,1-4H3,(H,39,49)(H,40,52)(H,41,44)(H,50,51) CTRBPZOBTGUKKG-UHFFFAOYSA-N 778189 US20250313574, Example A-047 Myeloid cell surface antigen CD33 22.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778189 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778189&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893331 523296536 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560607 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H51N5O11/c1-18(2)35-31(47)37-8-6-32(16-37)17-48-11-10-38(32)9-7-33(30(45)46)14-23(40)25(36-21(5)39)28(49-33)27(43)24(41)15-34-29(44)22-12-19(3)26(42)20(4)13-22/h12-13,18,23-25,27-28,40-43H,6-11,14-17H2,1-5H3,(H,34,44)(H,35,47)(H,36,39)(H,45,46) MDMLCZOLIQZMCV-UHFFFAOYSA-N 778190 US20250313574, Example A-048 Myeloid cell surface antigen CD33 24.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778190 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778190&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893332 523296537 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560608 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC24CC5CC(CC(C5)C2)C4)C3)(C(=O)O)C[C@@H]1O InChI=1S/C40H59N5O11/c1-22-10-28(11-23(2)32(22)49)35(51)41-19-30(48)33(50)34-31(42-24(3)46)29(47)18-40(56-34,36(52)53)5-7-45-8-9-55-21-39(45)4-6-44(20-39)37(54)43-38-15-25-12-26(16-38)14-27(13-25)17-38/h10-11,25-27,29-31,33-34,47-50H,4-9,12-21H2,1-3H3,(H,41,51)(H,42,46)(H,43,54)(H,52,53) ZYJUMRGGEZLGDL-UHFFFAOYSA-N 778191 US20250313574, Example A-049 Myeloid cell surface antigen CD33 41.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778191 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778191&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893333 523296538 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560609 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC(C)(C)C(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H57N5O11/c1-20(2)34(6,7)39-33(50)40-10-8-35(18-40)19-51-13-12-41(35)11-9-36(32(48)49)16-25(43)27(38-23(5)42)30(52-36)29(46)26(44)17-37-31(47)24-14-21(3)28(45)22(4)15-24/h14-15,20,25-27,29-30,43-46H,8-13,16-19H2,1-7H3,(H,37,47)(H,38,42)(H,39,50)(H,48,49) MFZBGVWPIFQKBZ-UHFFFAOYSA-N 778192 US20250313574, Example A-050 Myeloid cell surface antigen CD33 20.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778192 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778192&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893334 523296539 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560610 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC2CCC(F)(F)CC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H53F2N5O11/c1-20-14-23(15-21(2)28(20)47)31(49)39-17-26(46)29(48)30-27(40-22(3)44)25(45)16-35(54-30,32(50)51)9-11-43-12-13-53-19-34(43)8-10-42(18-34)33(52)41-24-4-6-36(37,38)7-5-24/h14-15,24-27,29-30,45-48H,4-13,16-19H2,1-3H3,(H,39,49)(H,40,44)(H,41,52)(H,50,51) XOYVFFANRIQSDV-UHFFFAOYSA-N 778193 US20250313574, Example A-051 Myeloid cell surface antigen CD33 64.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778193 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778193&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 170616068 523296540 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560611 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=S)NC2CCCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H55N5O10S/c1-21-15-24(16-22(2)29(21)45)32(47)37-18-27(44)30(46)31-28(38-23(3)42)26(43)17-36(51-31,33(48)49)10-12-41-13-14-50-20-35(41)9-11-40(19-35)34(52)39-25-7-5-4-6-8-25/h15-16,25-28,30-31,43-46H,4-14,17-20H2,1-3H3,(H,37,47)(H,38,42)(H,39,52)(H,48,49) AUYQDFVFJZHKIF-UHFFFAOYSA-N 778194 US20250313574, Example A-052 Myeloid cell surface antigen CD33 66.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778194 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778194&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893335 523296541 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560612 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)Nc2ccc(C)cc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H51N5O11/c1-21-5-7-26(8-6-21)40-35(51)41-11-9-36(19-41)20-52-14-13-42(36)12-10-37(34(49)50)17-27(44)29(39-24(4)43)32(53-37)31(47)28(45)18-38-33(48)25-15-22(2)30(46)23(3)16-25/h5-8,15-16,27-29,31-32,44-47H,9-14,17-20H2,1-4H3,(H,38,48)(H,39,43)(H,40,51)(H,49,50) IOJUYDSJWLANQC-UHFFFAOYSA-N 778195 US20250313574, Example A-053 Myeloid cell surface antigen CD33 147 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778195 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778195&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893336 523296542 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560613 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC2(c4ccccc4)CC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C39H53N5O11/c1-23-17-26(18-24(2)31(23)48)34(50)40-20-29(47)32(49)33-30(41-25(3)45)28(46)19-39(55-33,35(51)52)12-14-44-15-16-54-22-37(44)11-13-43(21-37)36(53)42-38(9-10-38)27-7-5-4-6-8-27/h4-8,17-18,28-30,32-33,46-49H,9-16,19-22H2,1-3H3,(H,40,50)(H,41,45)(H,42,53)(H,51,52) DGYIRRADGQIXEY-UHFFFAOYSA-N 778196 US20250313574, Example A-054 Myeloid cell surface antigen CD33 147 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778196 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778196&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893337 523296543 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560614 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC(C)(C)c2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C39H55N5O11/c1-23-17-26(18-24(2)31(23)48)34(50)40-20-29(47)32(49)33-30(41-25(3)45)28(46)19-39(55-33,35(51)52)12-14-44-15-16-54-22-38(44)11-13-43(21-38)36(53)42-37(4,5)27-9-7-6-8-10-27/h6-10,17-18,28-30,32-33,46-49H,11-16,19-22H2,1-5H3,(H,40,50)(H,41,45)(H,42,53)(H,51,52) MYSZROCBWDDVDT-UHFFFAOYSA-N 778197 US20250313574, Example A-055 Myeloid cell surface antigen CD33 247 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778197 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778197&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893338 523296544 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560615 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N[C@H](C)c2ccc(Br)cc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C38H52BrN5O11/c1-21-15-26(16-22(2)31(21)48)34(50)40-18-29(47)32(49)33-30(42-24(4)45)28(46)17-38(55-33,35(51)52)10-12-44-13-14-54-20-37(44)9-11-43(19-37)36(53)41-23(3)25-5-7-27(39)8-6-25/h5-8,15-16,23,28-30,32-33,46-49H,9-14,17-20H2,1-4H3,(H,40,50)(H,41,53)(H,42,45)(H,51,52) XLHIIYYXRRQFEF-UHFFFAOYSA-N 778198 US20250313574, Example A-056 Myeloid cell surface antigen CD33 153 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778198 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778198&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893339 523296545 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560616 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NC2(c4ccc(F)cc4)CCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C41H56FN5O11/c1-24-18-27(19-25(2)33(24)51)36(53)43-21-31(50)34(52)35-32(44-26(3)48)30(49)20-41(58-35,37(54)55)13-15-47-16-17-57-23-39(47)12-14-46(22-39)38(56)45-40(10-4-5-11-40)28-6-8-29(42)9-7-28/h6-9,18-19,30-32,34-35,49-52H,4-5,10-17,20-23H2,1-3H3,(H,43,53)(H,44,48)(H,45,56)(H,54,55) TXMQGDSKUFBRLB-UHFFFAOYSA-N 778199 US20250313574, Example A-057 Myeloid cell surface antigen CD33 265 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778199 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778199&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893340 523296546 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560617 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=S)NC2CC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H49N5O10S/c1-18-12-21(13-19(2)26(18)42)29(44)34-15-24(41)27(43)28-25(35-20(3)39)23(40)14-33(48-28,30(45)46)7-9-38-10-11-47-17-32(38)6-8-37(16-32)31(49)36-22-4-5-22/h12-13,22-25,27-28,40-43H,4-11,14-17H2,1-3H3,(H,34,44)(H,35,39)(H,36,49)(H,45,46) PMVCMGMOBAJUEW-UHFFFAOYSA-N 778200 US20250313574, Example A-058 Myeloid cell surface antigen CD33 1380 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778200 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778200&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893341 523296547 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560618 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N(C)c2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H51N5O11/c1-22-16-25(17-23(2)30(22)46)33(48)38-19-28(45)31(47)32-29(39-24(3)43)27(44)18-37(53-32,34(49)50)11-13-42-14-15-52-21-36(42)10-12-41(20-36)35(51)40(4)26-8-6-5-7-9-26/h5-9,16-17,27-29,31-32,44-47H,10-15,18-21H2,1-4H3,(H,38,48)(H,39,43)(H,49,50) FGNBROYDGHOARY-UHFFFAOYSA-N 778201 US20250313574, Example A-059 Myeloid cell surface antigen CD33 60.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778201 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778201&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893342 523296548 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560619 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H52N4O11/c1-20-14-24(15-21(2)28(20)43)31(45)36-17-26(42)29(44)30-27(37-22(3)40)25(41)16-35(50-30,33(47)48)9-11-39-12-13-49-19-34(39)8-10-38(18-34)32(46)23-6-4-5-7-23/h14-15,23,25-27,29-30,41-44H,4-13,16-19H2,1-3H3,(H,36,45)(H,37,40)(H,47,48) ZFYZEHHISDTEQP-UHFFFAOYSA-N 778202 US20250313574, Example A-060 Myeloid cell surface antigen CD33 65.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778202 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778202&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893343 523296549 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560620 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N(C)C(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H53N5O11/c1-19(2)37(6)32(48)38-9-7-33(17-38)18-49-12-11-39(33)10-8-34(31(46)47)15-24(41)26(36-22(5)40)29(50-34)28(44)25(42)16-35-30(45)23-13-20(3)27(43)21(4)14-23/h13-14,19,24-26,28-29,41-44H,7-12,15-18H2,1-6H3,(H,35,45)(H,36,40)(H,46,47) SWEHZQOXMZMVHK-UHFFFAOYSA-N 778203 US20250313574, Example A-061 Myeloid cell surface antigen CD33 235 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778203 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778203&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893344 523296550 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560621 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N2CCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H51N5O11/c1-20-14-23(15-21(2)27(20)43)30(45)35-17-25(42)28(44)29-26(36-22(3)40)24(41)16-34(50-29,31(46)47)7-11-39-12-13-49-19-33(39)6-10-38(18-33)32(48)37-8-4-5-9-37/h14-15,24-26,28-29,41-44H,4-13,16-19H2,1-3H3,(H,35,45)(H,36,40)(H,46,47) FDVBSSNNSFRFCL-UHFFFAOYSA-N 778204 US20250313574, Example A-062 Myeloid cell surface antigen CD33 833 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778204 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778204&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893345 523296551 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560622 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N(C)Cc2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C38H53N5O11/c1-23-16-27(17-24(2)31(23)47)34(49)39-19-29(46)32(48)33-30(40-25(3)44)28(45)18-38(54-33,35(50)51)11-13-43-14-15-53-22-37(43)10-12-42(21-37)36(52)41(4)20-26-8-6-5-7-9-26/h5-9,16-17,28-30,32-33,45-48H,10-15,18-22H2,1-4H3,(H,39,49)(H,40,44)(H,50,51) SDDUFVXCAUQIEU-UHFFFAOYSA-N 778205 US20250313574, Example A-063 Myeloid cell surface antigen CD33 323 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778205 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778205&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893346 523296552 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560623 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H49N5O11/c1-18-12-21(13-19(2)25(18)41)28(43)33-15-23(40)26(42)27-24(34-20(3)38)22(39)14-32(48-27,29(44)45)7-9-37-10-11-47-17-31(37)6-8-36(16-31)30(46)35(4)5/h12-13,22-24,26-27,39-42H,6-11,14-17H2,1-5H3,(H,33,43)(H,34,38)(H,44,45) KNALXTXJXVEKDL-UHFFFAOYSA-N 778206 US20250313574, Example A-064 Myeloid cell surface antigen CD33 3500 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778206 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778206&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893347 523296553 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560624 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)N2CCC(F)(F)CC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H51F2N5O11/c1-20-14-23(15-21(2)27(20)46)30(48)38-17-25(45)28(47)29-26(39-22(3)43)24(44)16-34(53-29,31(49)50)5-11-42-12-13-52-19-33(42)4-8-41(18-33)32(51)40-9-6-35(36,37)7-10-40/h14-15,24-26,28-29,44-47H,4-13,16-19H2,1-3H3,(H,38,48)(H,39,43)(H,49,50) YBRSDQDMUATZNY-UHFFFAOYSA-N 778207 US20250313574, Example A-065 Myeloid cell surface antigen CD33 739 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778207 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778207&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893348 523296554 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560625 CCN(CC)C(=O)N1CC[C@@]2(COCCN2CC[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)C1 InChI=1S/C34H53N5O11/c1-6-37(7-2)32(48)38-10-8-33(18-38)19-49-13-12-39(33)11-9-34(31(46)47)16-24(41)26(36-22(5)40)29(50-34)28(44)25(42)17-35-30(45)23-14-20(3)27(43)21(4)15-23/h14-15,24-26,28-29,41-44H,6-13,16-19H2,1-5H3,(H,35,45)(H,36,40)(H,46,47) DKHRDSNYGFVXTK-UHFFFAOYSA-N 778208 US20250313574, Example A-066 Myeloid cell surface antigen CD33 156 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778208 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778208&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893349 523296555 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560626 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CCCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H54N4O11/c1-21-15-25(16-22(2)29(21)44)32(46)37-18-27(43)30(45)31-28(38-23(3)41)26(42)17-36(51-31,34(48)49)10-12-40-13-14-50-20-35(40)9-11-39(19-35)33(47)24-7-5-4-6-8-24/h15-16,24,26-28,30-31,42-45H,4-14,17-20H2,1-3H3,(H,37,46)(H,38,41)(H,48,49) OWXFDQFCBLBFLL-UHFFFAOYSA-N 778209 US20250313574, Example A-067 Myeloid cell surface antigen CD33 63.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778209 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778209&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893350 523296556 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560627 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)CC(C)c2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C39H54N4O11/c1-23(27-8-6-5-7-9-27)18-31(47)42-12-10-38(21-42)22-53-15-14-43(38)13-11-39(37(51)52)19-29(45)32(41-26(4)44)35(54-39)34(49)30(46)20-40-36(50)28-16-24(2)33(48)25(3)17-28/h5-9,16-17,23,29-30,32,34-35,45-46,48-49H,10-15,18-22H2,1-4H3,(H,40,50)(H,41,44)(H,51,52) NTYVSNOTYYMNPR-UHFFFAOYSA-N 778210 US20250313574, Example A-068 Myeloid cell surface antigen CD33 101 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778210 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778210&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893351 523296557 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560628 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CC4(C2)CC(F)(F)C4)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H52F2N4O11/c1-20-10-23(11-21(2)28(20)47)31(49)40-15-26(46)29(48)30-27(41-22(3)44)25(45)14-36(54-30,33(51)52)5-7-43-8-9-53-19-35(43)4-6-42(18-35)32(50)24-12-34(13-24)16-37(38,39)17-34/h10-11,24-27,29-30,45-48H,4-9,12-19H2,1-3H3,(H,40,49)(H,41,44)(H,51,52) UKGMSRIWHAGDHN-UHFFFAOYSA-N 778211 US20250313574, Example A-069 Myeloid cell surface antigen CD33 123 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778211 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778211&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893352 523296558 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560629 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CCCCC2(F)F)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H52F2N4O11/c1-20-14-23(15-21(2)28(20)46)31(48)39-17-26(45)29(47)30-27(40-22(3)43)25(44)16-35(53-30,33(50)51)9-11-42-12-13-52-19-34(42)8-10-41(18-34)32(49)24-6-4-5-7-36(24,37)38/h14-15,24-27,29-30,44-47H,4-13,16-19H2,1-3H3,(H,39,48)(H,40,43)(H,50,51) GOBLSSGNIKOBIY-UHFFFAOYSA-N 778212 US20250313574, Example A-070 Myeloid cell surface antigen CD33 31.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778212 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778212&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893353 523296559 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560630 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2(C)CCCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H56N4O11/c1-22-16-25(17-23(2)29(22)45)32(47)38-19-27(44)30(46)31-28(39-24(3)42)26(43)18-37(52-31,34(49)50)11-13-41-14-15-51-21-36(41)10-12-40(20-36)33(48)35(4)8-6-5-7-9-35/h16-17,26-28,30-31,43-46H,5-15,18-21H2,1-4H3,(H,38,47)(H,39,42)(H,49,50) OQWBVXXOQYMIRZ-UHFFFAOYSA-N 778213 US20250313574, Example A-071 Myeloid cell surface antigen CD33 41.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778213 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778213&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292863 523296560 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560631 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)CC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O11/c1-20-13-23(14-21(2)28(20)44)31(46)36-17-25(42)29(45)30-27(37-22(3)40)24(41)15-35(50-30,32(47)48)8-10-39-11-12-49-19-34(39)7-9-38(18-34)26(43)16-33(4,5)6/h13-14,24-25,27,29-30,41-42,44-45H,7-12,15-19H2,1-6H3,(H,36,46)(H,37,40)(H,47,48) HOLTXKSCFKITOL-UHFFFAOYSA-N 778214 US20250313574, Example A-072 Myeloid cell surface antigen CD33 230 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778214 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778214&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292805 523296561 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560632 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)CC2CCOCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H54N4O12/c1-21-14-25(15-22(2)30(21)45)33(47)37-18-27(43)31(46)32-29(38-23(3)41)26(42)17-36(52-32,34(48)49)7-9-40-10-13-51-20-35(40)6-8-39(19-35)28(44)16-24-4-11-50-12-5-24/h14-15,24,26-27,29,31-32,42-43,45-46H,4-13,16-20H2,1-3H3,(H,37,47)(H,38,41)(H,48,49) WOERMSTUGGXLQB-UHFFFAOYSA-N 778215 US20250313574, Example A-073 Myeloid cell surface antigen CD33 206 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778215 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778215&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292835 523296562 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560633 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CCC(F)(F)C2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H50F2N4O11/c1-19-12-23(13-20(2)27(19)45)30(47)38-16-25(44)28(46)29-26(39-21(3)42)24(43)15-34(52-29,32(49)50)7-9-41-10-11-51-18-33(41)6-8-40(17-33)31(48)22-4-5-35(36,37)14-22/h12-13,22,24-26,28-29,43-46H,4-11,14-18H2,1-3H3,(H,38,47)(H,39,42)(H,49,50) WZVXXFXALSDPPS-UHFFFAOYSA-N 778216 US20250313574, Example A-074 Myeloid cell surface antigen CD33 263 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778216 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778216&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292792 523296563 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560634 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CCC(F)(F)CC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H52F2N4O11/c1-20-14-24(15-21(2)28(20)46)31(48)39-17-26(45)29(47)30-27(40-22(3)43)25(44)16-35(53-30,33(50)51)9-11-42-12-13-52-19-34(42)8-10-41(18-34)32(49)23-4-6-36(37,38)7-5-23/h14-15,23,25-27,29-30,44-47H,4-13,16-19H2,1-3H3,(H,39,48)(H,40,43)(H,50,51) QFPNPHZZHZFKQQ-UHFFFAOYSA-N 778217 US20250313574, Example A-075 Myeloid cell surface antigen CD33 99.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778217 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778217&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292960 523296564 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560635 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C(C)C2CCCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C38H58N4O11/c1-22-16-27(17-23(2)31(22)46)34(48)39-19-29(45)32(47)33-30(40-25(4)43)28(44)18-38(53-33,36(50)51)11-13-42-14-15-52-21-37(42)10-12-41(20-37)35(49)24(3)26-8-6-5-7-9-26/h16-17,24,26,28-30,32-33,44-47H,5-15,18-21H2,1-4H3,(H,39,48)(H,40,43)(H,50,51) YLXSTYCQXMWFEX-UHFFFAOYSA-N 778218 US20250313574, Example A-076 Myeloid cell surface antigen CD33 226 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778218 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778218&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292721 523296565 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560636 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2(C)CCCO2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H52N4O12/c1-20-14-23(15-21(2)27(20)43)30(45)36-17-25(42)28(44)29-26(37-22(3)40)24(41)16-35(51-29,32(47)48)8-10-39-11-13-49-19-34(39)7-9-38(18-34)31(46)33(4)6-5-12-50-33/h14-15,24-26,28-29,41-44H,5-13,16-19H2,1-4H3,(H,36,45)(H,37,40)(H,47,48) AAINYFUUCMPKJF-UHFFFAOYSA-N 778219 US20250313574, Example A-077 Myeloid cell surface antigen CD33 283 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778219 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778219&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893354 523296566 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560637 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C=C(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N4O11/c1-19(2)12-26(42)37-8-6-33(17-37)18-48-11-10-38(33)9-7-34(32(46)47)15-24(40)27(36-22(5)39)30(49-34)29(44)25(41)16-35-31(45)23-13-20(3)28(43)21(4)14-23/h12-14,24-25,27,29-30,40-41,43-44H,6-11,15-18H2,1-5H3,(H,35,45)(H,36,39)(H,46,47) ZLTPUTBHPSLITQ-UHFFFAOYSA-N 778220 US20250313574, Example A-078 Myeloid cell surface antigen CD33 115 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778220 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778220&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292838 523296567 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560638 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)NCc2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H51N5O11/c1-22-15-26(16-23(2)30(22)46)33(48)38-19-28(45)31(47)32-29(40-24(3)43)27(44)17-37(53-32,34(49)50)10-12-42-13-14-52-21-36(42)9-11-41(20-36)35(51)39-18-25-7-5-4-6-8-25/h4-8,15-16,27-29,31-32,44-47H,9-14,17-21H2,1-3H3,(H,38,48)(H,39,51)(H,40,43)(H,49,50) HAHZOKYWSWKNNA-UHFFFAOYSA-N 778221 US20250313574, Example A-079 Myeloid cell surface antigen CD33 152 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778221 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778221&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292720 523296568 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560639 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CC(C)(C)C2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H54N4O11/c1-20-12-23(13-21(2)28(20)44)31(46)37-17-26(43)29(45)30-27(38-22(3)41)25(42)16-36(51-30,33(48)49)7-9-40-10-11-50-19-35(40)6-8-39(18-35)32(47)24-14-34(4,5)15-24/h12-13,24-27,29-30,42-45H,6-11,14-19H2,1-5H3,(H,37,46)(H,38,41)(H,48,49) JENNGVFRCMCUJZ-UHFFFAOYSA-N 778222 US20250313574, Example A-080 Myeloid cell surface antigen CD33 68.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778222 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778222&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292746 523296569 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560640 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C(C)(C)Oc2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C39H54N4O12/c1-23-17-26(18-24(2)31(23)47)34(49)40-20-29(46)32(48)33-30(41-25(3)44)28(45)19-39(55-33,36(51)52)12-14-43-15-16-53-22-38(43)11-13-42(21-38)35(50)37(4,5)54-27-9-7-6-8-10-27/h6-10,17-18,28-30,32-33,45-48H,11-16,19-22H2,1-5H3,(H,40,49)(H,41,44)(H,51,52) USUQQTSGJFXWOA-UHFFFAOYSA-N 778223 US20250313574, Example A-081 Myeloid cell surface antigen CD33 1950 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778223 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778223&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292866 523296570 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560641 COC(C)C(=O)N1CC[C@@]2(COCCN2CC[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)C1 InChI=1S/C33H50N4O12/c1-18-12-22(13-19(2)26(18)41)29(43)34-15-24(40)27(42)28-25(35-21(4)38)23(39)14-33(49-28,31(45)46)7-9-37-10-11-48-17-32(37)6-8-36(16-32)30(44)20(3)47-5/h12-13,20,23-25,27-28,39-42H,6-11,14-17H2,1-5H3,(H,34,43)(H,35,38)(H,45,46) RVQLLAFYQOFRQK-UHFFFAOYSA-N 778224 US20250313574, Example A-082 Myeloid cell surface antigen CD33 >5000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778224 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778224&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292841 523296571 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560642 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)COCC(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O12/c1-20(2)16-50-17-27(43)38-8-6-34(18-38)19-49-11-10-39(34)9-7-35(33(47)48)14-25(41)28(37-23(5)40)31(51-35)30(45)26(42)15-36-32(46)24-12-21(3)29(44)22(4)13-24/h12-13,20,25-26,28,30-31,41-42,44-45H,6-11,14-19H2,1-5H3,(H,36,46)(H,37,40)(H,47,48) QDJKMOLNUDITRD-UHFFFAOYSA-N 778225 US20250313574, Example A-083 Myeloid cell surface antigen CD33 1000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778225 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778225&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292945 523296572 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560643 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)COC(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O12/c1-19(2)49-16-26(42)37-8-6-33(17-37)18-48-11-10-38(33)9-7-34(32(46)47)14-24(40)27(36-22(5)39)30(50-34)29(44)25(41)15-35-31(45)23-12-20(3)28(43)21(4)13-23/h12-13,19,24-25,27,29-30,40-41,43-44H,6-11,14-18H2,1-5H3,(H,35,45)(H,36,39)(H,46,47) IFZMOVPWXPIAKG-UHFFFAOYSA-N 778226 US20250313574, Example A-084 Myeloid cell surface antigen CD33 1560 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778226 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778226&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292751 523296573 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560644 COC(C)(C)C(=O)N1CC[C@@]2(COCCN2CC[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)C1 InChI=1S/C34H52N4O12/c1-19-13-22(14-20(2)26(19)42)29(44)35-16-24(41)27(43)28-25(36-21(3)39)23(40)15-34(50-28,31(46)47)8-10-38-11-12-49-18-33(38)7-9-37(17-33)30(45)32(4,5)48-6/h13-14,23-25,27-28,40-43H,7-12,15-18H2,1-6H3,(H,35,44)(H,36,39)(H,46,47) YUDXUXPZSOGWMQ-UHFFFAOYSA-N 778227 US20250313574, Example A-085 Myeloid cell surface antigen CD33 1280 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778227 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778227&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292823 523296574 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560645 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)c2c(C)cccc2C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C38H52N4O11/c1-21-7-6-8-22(2)29(21)35(49)41-11-9-37(19-41)20-52-14-13-42(37)12-10-38(36(50)51)17-27(44)30(40-25(5)43)33(53-38)32(47)28(45)18-39-34(48)26-15-23(3)31(46)24(4)16-26/h6-8,15-16,27-28,30,32-33,44-47H,9-14,17-20H2,1-5H3,(H,39,48)(H,40,43)(H,50,51) ZXGDUYVEJHELQH-UHFFFAOYSA-N 778228 US20250313574, Example A-086 Myeloid cell surface antigen CD33 >5000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778228 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778228&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292811 523296575 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560646 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)c2ccccn2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H47N5O11/c1-20-14-23(15-21(2)28(20)44)31(46)37-17-26(43)29(45)30-27(38-22(3)41)25(42)16-35(51-30,33(48)49)8-11-40-12-13-50-19-34(40)7-10-39(18-34)32(47)24-6-4-5-9-36-24/h4-6,9,14-15,25-27,29-30,42-45H,7-8,10-13,16-19H2,1-3H3,(H,37,46)(H,38,41)(H,48,49) DWSIFWAXDBTOAR-UHFFFAOYSA-N 778229 US20250313574, Example A-087 Myeloid cell surface antigen CD33 5260 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778229 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778229&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292725 523296576 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560647 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)COCC(F)(F)F)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1cc(C)c(O)c(C)c1 InChI=1S/C33H47F3N4O12/c1-18-10-21(11-19(2)26(18)45)29(47)37-13-23(43)27(46)28-25(38-20(3)41)22(42)12-32(52-28,30(48)49)5-7-40-8-9-50-16-31(40)4-6-39(15-31)24(44)14-51-17-33(34,35)36/h10-11,22-23,25,27-28,42-43,45-46H,4-9,12-17H2,1-3H3,(H,37,47)(H,38,41)(H,48,49) FIPNAZJOGGXJCB-UHFFFAOYSA-N 778230 US20250313574, Example A-088 Myeloid cell surface antigen CD33 1950 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778230 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778230&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893355 523296577 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560648 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C(c2ccccc2)C2CCCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C43H60N4O11/c1-26-20-31(21-27(2)36(26)51)39(53)44-23-33(50)37(52)38-35(45-28(3)48)32(49)22-43(58-38,41(55)56)15-17-47-18-19-57-25-42(47)14-16-46(24-42)40(54)34(29-10-6-4-7-11-29)30-12-8-5-9-13-30/h4,6-7,10-11,20-21,30,32-35,37-38,49-52H,5,8-9,12-19,22-25H2,1-3H3,(H,44,53)(H,45,48)(H,55,56) FUPGXZZQILERJY-UHFFFAOYSA-N 778231 US20250313574, Example A-089 Myeloid cell surface antigen CD33 291 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778231 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778231&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292772 523296578 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560649 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)COC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O12/c1-20-13-23(14-21(2)28(20)44)31(46)36-16-25(42)29(45)30-27(37-22(3)40)24(41)15-35(51-30,32(47)48)8-10-39-11-12-49-19-34(39)7-9-38(18-34)26(43)17-50-33(4,5)6/h13-14,24-25,27,29-30,41-42,44-45H,7-12,15-19H2,1-6H3,(H,36,46)(H,37,40)(H,47,48) MUNGXJFUXINAKD-UHFFFAOYSA-N 778232 US20250313574, Example A-090 Myeloid cell surface antigen CD33 3120 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778232 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778232&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292956 523296579 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560650 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CCOCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H52N4O12/c1-20-14-24(15-21(2)28(20)43)31(45)36-17-26(42)29(44)30-27(37-22(3)40)25(41)16-35(51-30,33(47)48)7-9-39-10-13-50-19-34(39)6-8-38(18-34)32(46)23-4-11-49-12-5-23/h14-15,23,25-27,29-30,41-44H,4-13,16-19H2,1-3H3,(H,36,45)(H,37,40)(H,47,48) ISKHBNGTZQDYNI-UHFFFAOYSA-N 778233 US20250313574, Example A-091 Myeloid cell surface antigen CD33 452 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778233 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778233&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292941 523296580 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560651 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)COC2CCCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H54N4O12/c1-21-14-24(15-22(2)30(21)45)33(47)37-17-27(43)31(46)32-29(38-23(3)41)26(42)16-36(52-32,34(48)49)9-11-40-12-13-50-20-35(40)8-10-39(19-35)28(44)18-51-25-6-4-5-7-25/h14-15,25-27,29,31-32,42-43,45-46H,4-13,16-20H2,1-3H3,(H,37,47)(H,38,41)(H,48,49) NUBLXAWWYHEBFQ-UHFFFAOYSA-N 778234 US20250313574, Example A-092 Myeloid cell surface antigen CD33 2050 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778234 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778234&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292734 523296581 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560652 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)c2ccco2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H46N4O12/c1-19-13-22(14-20(2)27(19)42)30(44)35-16-24(41)28(43)29-26(36-21(3)39)23(40)15-34(50-29,32(46)47)7-9-38-10-12-48-18-33(38)6-8-37(17-33)31(45)25-5-4-11-49-25/h4-5,11,13-14,23-24,26,28-29,40-43H,6-10,12,15-18H2,1-3H3,(H,35,44)(H,36,39)(H,46,47) XDCVEVFRVNJJNA-UHFFFAOYSA-N 778235 US20250313574, Example A-093 Myeloid cell surface antigen CD33 892 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778235 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778235&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292851 523296582 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560653 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)c2ccc4[nH]cnc4c2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H48N6O11/c1-20-12-24(13-21(2)30(20)47)33(49)38-16-28(46)31(48)32-29(41-22(3)44)27(45)15-37(54-32,35(51)52)7-9-43-10-11-53-18-36(43)6-8-42(17-36)34(50)23-4-5-25-26(14-23)40-19-39-25/h4-5,12-14,19,27-29,31-32,45-48H,6-11,15-18H2,1-3H3,(H,38,49)(H,39,40)(H,41,44)(H,51,52) VRUHGKFDLVUGDH-UHFFFAOYSA-N 778236 US20250313574, Example A-094 Myeloid cell surface antigen CD33 2330 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778236 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778236&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292790 523296583 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560654 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)c2ccc4[nH]c(C(C)O)nc4c2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C39H52N6O12/c1-20-13-25(14-21(2)31(20)50)35(52)40-17-29(49)32(51)33-30(41-23(4)47)28(48)16-39(57-33,37(54)55)8-10-45-11-12-56-19-38(45)7-9-44(18-38)36(53)24-5-6-26-27(15-24)43-34(42-26)22(3)46/h5-6,13-15,22,28-30,32-33,46,48-51H,7-12,16-19H2,1-4H3,(H,40,52)(H,41,47)(H,42,43)(H,54,55) YREMSQXXJDMHOL-UHFFFAOYSA-N 778237 US20250313574, Example A-095 Myeloid cell surface antigen CD33 1690 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778237 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778237&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292795 523296584 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560655 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2CC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H48N4O11/c1-18-12-22(13-19(2)26(18)41)29(43)34-15-24(40)27(42)28-25(35-20(3)38)23(39)14-33(48-28,31(45)46)7-9-37-10-11-47-17-32(37)6-8-36(16-32)30(44)21-4-5-21/h12-13,21,23-25,27-28,39-42H,4-11,14-17H2,1-3H3,(H,34,43)(H,35,38)(H,45,46) NIQDUZFGQMBHSL-UHFFFAOYSA-N 778238 US20250313574, Example A-096 Myeloid cell surface antigen CD33 454 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778238 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778238&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292865 523296585 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560656 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O11/c1-19-13-22(14-20(2)26(19)42)29(44)35-16-24(41)27(43)28-25(36-21(3)39)23(40)15-34(49-28,31(46)47)8-10-38-11-12-48-18-33(38)7-9-37(17-33)30(45)32(4,5)6/h13-14,23-25,27-28,40-43H,7-12,15-18H2,1-6H3,(H,35,44)(H,36,39)(H,46,47) ZASMDKRLFJSQOR-UHFFFAOYSA-N 778239 US20250313574, Example A-097 Myeloid cell surface antigen CD33 430 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778239 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778239&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292889 523296586 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560657 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2(c4ccccc4)CC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C39H52N4O11/c1-23-17-26(18-24(2)31(23)47)34(49)40-20-29(46)32(48)33-30(41-25(3)44)28(45)19-39(54-33,36(51)52)12-14-43-15-16-53-22-37(43)11-13-42(21-37)35(50)38(9-10-38)27-7-5-4-6-8-27/h4-8,17-18,28-30,32-33,45-48H,9-16,19-22H2,1-3H3,(H,40,49)(H,41,44)(H,51,52) CTHYVCPPDDFTHM-UHFFFAOYSA-N 778240 US20250313574, Example A-098 Myeloid cell surface antigen CD33 685 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778240 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778240&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292885 523296587 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560658 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)c2ccc(C)cc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H50N4O11/c1-21-5-7-25(8-6-21)34(48)40-11-9-36(19-40)20-51-14-13-41(36)12-10-37(35(49)50)17-27(43)29(39-24(4)42)32(52-37)31(46)28(44)18-38-33(47)26-15-22(2)30(45)23(3)16-26/h5-8,15-16,27-29,31-32,43-46H,9-14,17-20H2,1-4H3,(H,38,47)(H,39,42)(H,49,50) NAYKOTBRYDPZLE-UHFFFAOYSA-N 778241 US20250313574, Example A-099 Myeloid cell surface antigen CD33 342 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778241 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778241&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292757 523296588 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560659 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2(C)COC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N4O12/c1-19-11-22(12-20(2)26(19)42)29(44)35-14-24(41)27(43)28-25(36-21(3)39)23(40)13-34(50-28,31(46)47)6-8-38-9-10-48-18-33(38)5-7-37(15-33)30(45)32(4)16-49-17-32/h11-12,23-25,27-28,40-43H,5-10,13-18H2,1-4H3,(H,35,44)(H,36,39)(H,46,47) BCKUBXRKZUIRSL-UHFFFAOYSA-N 778242 US20250313574, Example A-100 Myeloid cell surface antigen CD33 2340 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778242 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778242&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292833 523296589 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560660 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)c2ccccc2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H48N4O11/c1-21-15-25(16-22(2)29(21)44)32(46)37-18-27(43)30(45)31-28(38-23(3)41)26(42)17-36(51-31,34(48)49)10-12-40-13-14-50-20-35(40)9-11-39(19-35)33(47)24-7-5-4-6-8-24/h4-8,15-16,26-28,30-31,42-45H,9-14,17-20H2,1-3H3,(H,37,46)(H,38,41)(H,48,49) JFODXNAFWYSDQI-UHFFFAOYSA-N 778243 US20250313574, Example A-101 Myeloid cell surface antigen CD33 921 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778243 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778243&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893356 523296590 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560661 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)C2(C(F)(F)F)CCCCC2)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1cc(C)c(O)c(C)c1 InChI=1S/C37H53F3N4O11/c1-21-15-24(16-22(2)28(21)48)31(50)41-18-26(47)29(49)30-27(42-23(3)45)25(46)17-36(55-30,33(52)53)10-12-44-13-14-54-20-34(44)9-11-43(19-34)32(51)35(37(38,39)40)7-5-4-6-8-35/h15-16,25-27,29-30,46-49H,4-14,17-20H2,1-3H3,(H,41,50)(H,42,45)(H,52,53) UAWHKDXNYGGDAK-UHFFFAOYSA-N 778244 US20250313574, Example A-102 Myeloid cell surface antigen CD33 397 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778244 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778244&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893357 523296591 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560662 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)C2(C)CCC2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H52N4O11/c1-20-14-23(15-21(2)27(20)43)30(45)36-17-25(42)28(44)29-26(37-22(3)40)24(41)16-35(50-29,32(47)48)9-11-39-12-13-49-19-34(39)8-10-38(18-34)31(46)33(4)6-5-7-33/h14-15,24-26,28-29,41-44H,5-13,16-19H2,1-4H3,(H,36,45)(H,37,40)(H,47,48) VAIANDWVNHMPHT-UHFFFAOYSA-N 778245 US20250313574, Example A-103 Myeloid cell surface antigen CD33 1020 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778245 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778245&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292785 523296592 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560663 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(Cc2cccc(C)c2)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H52N4O10/c1-22-6-5-7-26(14-22)19-40-10-8-36(20-40)21-50-13-12-41(36)11-9-37(35(48)49)17-28(43)30(39-25(4)42)33(51-37)32(46)29(44)18-38-34(47)27-15-23(2)31(45)24(3)16-27/h5-7,14-16,28-30,32-33,43-46H,8-13,17-21H2,1-4H3,(H,38,47)(H,39,42)(H,48,49) QFMASUDVIBNHMB-UHFFFAOYSA-N 778246 US20250313574, Example A-104 Myeloid cell surface antigen CD33 >10000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778246 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778246&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292845 523296593 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560664 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCN(C)C[C@@]23CCN(C(=O)NC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H56N6O10/c1-20-14-23(15-21(2)27(20)45)30(47)36-17-25(44)28(46)29-26(37-22(3)42)24(43)16-35(51-29,31(48)49)9-11-41-13-12-39(7)18-34(41)8-10-40(19-34)32(50)38-33(4,5)6/h14-15,24-26,28-29,43-46H,8-13,16-19H2,1-7H3,(H,36,47)(H,37,42)(H,38,50)(H,48,49) GAOHXVZRTVFUHM-UHFFFAOYSA-N 778247 US20250313574, Example A-105 Myeloid cell surface antigen CD33 8.00 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778247 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778247&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893358 523296594 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560665 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCN(C)C[C@]23CCN(C(=O)NC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H56N6O10/c1-20-14-23(15-21(2)27(20)45)30(47)36-17-25(44)28(46)29-26(37-22(3)42)24(43)16-35(51-29,31(48)49)9-11-41-13-12-39(7)18-34(41)8-10-40(19-34)32(50)38-33(4,5)6/h14-15,24-26,28-29,43-46H,8-13,16-19H2,1-7H3,(H,36,47)(H,37,42)(H,38,50)(H,48,49) GAOHXVZRTVFUHM-UHFFFAOYSA-N 778248 US20250313574, Example A-106 Myeloid cell surface antigen CD33 1950 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778248 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778248&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893359 523296595 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560666 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCNC[C@]23CCN(C(=O)NC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H54N6O10/c1-19-13-22(14-20(2)26(19)44)29(46)36-16-24(43)27(45)28-25(37-21(3)41)23(42)15-34(50-28,30(47)48)8-11-40-12-9-35-17-33(40)7-10-39(18-33)31(49)38-32(4,5)6/h13-14,23-25,27-28,35,42-45H,7-12,15-18H2,1-6H3,(H,36,46)(H,37,41)(H,38,49)(H,47,48) KODSDNATXLJLBM-UHFFFAOYSA-N 778249 US20250313574, Example A-107 Myeloid cell surface antigen CD33 379 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778249 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778249&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893360 523296596 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560667 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCNC[C@@]23CCN(C(=O)NC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H54N6O10/c1-19-13-22(14-20(2)26(19)44)29(46)36-16-24(43)27(45)28-25(37-21(3)41)23(42)15-34(50-28,30(47)48)8-11-40-12-9-35-17-33(40)7-10-39(18-33)31(49)38-32(4,5)6/h13-14,23-25,27-28,35,42-45H,7-12,15-18H2,1-6H3,(H,36,46)(H,37,41)(H,38,49)(H,47,48) KODSDNATXLJLBM-UHFFFAOYSA-N 778250 US20250313574, Example A-108 Myeloid cell surface antigen CD33 26.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778250 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778250&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893361 523296597 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560668 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c3[nH]ccc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H51N5O11/c1-20-14-23(15-22-6-9-36-26(20)22)30(45)37-17-25(43)28(44)29-27(38-21(2)41)24(42)16-35(50-29,31(46)47)8-11-40-12-13-49-19-34(40)7-10-39(18-34)32(48)51-33(3,4)5/h6,9,14-15,24-25,27-29,36,42-44H,7-8,10-13,16-19H2,1-5H3,(H,37,45)(H,38,41)(H,46,47) QFPUJVLQEDMESH-UHFFFAOYSA-N 778251 US20250313574, Example A-109 Myeloid cell surface antigen CD33 6.00 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778251 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778251&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893362 523296598 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560669 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3ncsc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H47N5O11S/c1-19(39)36-25-22(40)14-33(29(44)45,8-10-38-11-12-47-17-32(38)7-9-37(16-32)30(46)49-31(2,3)4)48-27(25)26(42)23(41)15-34-28(43)20-5-6-21-24(13-20)50-18-35-21/h5-6,13,18,22-23,25-27,40-42H,7-12,14-17H2,1-4H3,(H,34,43)(H,36,39)(H,44,45) HCARUUNZBVKUNE-UHFFFAOYSA-N 778252 US20250313574, Example A-110 Myeloid cell surface antigen CD33 30.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778252 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778252&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893363 523296599 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560670 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c3[nH]ncc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N6O11/c1-19-12-21(13-22-15-36-38-25(19)22)29(45)35-16-24(43)27(44)28-26(37-20(2)41)23(42)14-34(50-28,30(46)47)7-9-40-10-11-49-18-33(40)6-8-39(17-33)31(48)51-32(3,4)5/h12-13,15,23-24,26-28,42-44H,6-11,14,16-18H2,1-5H3,(H,35,45)(H,36,38)(H,37,41)(H,46,47) JJDLXXGAJZVBRG-UHFFFAOYSA-N 778253 US20250313574, Example A-111 Myeloid cell surface antigen CD33 16.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778253 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778253&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893364 523296600 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560671 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3[nH]cc(C)c3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H51N5O11/c1-20-16-36-24-7-6-22(14-23(20)24)30(45)37-17-26(43)28(44)29-27(38-21(2)41)25(42)15-35(50-29,31(46)47)9-11-40-12-13-49-19-34(40)8-10-39(18-34)32(48)51-33(3,4)5/h6-7,14,16,25-29,36,42-44H,8-13,15,17-19H2,1-5H3,(H,37,45)(H,38,41)(H,46,47) FSFIYIQDIQAGJQ-UHFFFAOYSA-N 778254 US20250313574, Example A-112 Myeloid cell surface antigen CD33 22.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778254 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778254&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893365 523296601 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560672 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2c[nH]c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C31H49N5O11/c1-18-12-20(14-32-18)26(41)33-15-22(39)24(40)25-23(34-19(2)37)21(38)13-31(46-25,27(42)43)7-9-36-10-11-45-17-30(36)6-8-35(16-30)28(44)47-29(3,4)5/h12,14,21-25,32,38-40H,6-11,13,15-17H2,1-5H3,(H,33,41)(H,34,37)(H,42,43) DQNRSGXSVHQMRQ-UHFFFAOYSA-N 778255 US20250313574, Example A-113 Myeloid cell surface antigen CD33 34.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778255 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778255&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893366 523296602 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560673 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3ncccc3n2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H48N6O11/c1-20(41)37-26-24(42)16-34(30(46)47,10-13-40-14-15-49-19-33(40)9-12-39(18-33)31(48)51-32(2,3)4)50-28(26)27(44)25(43)17-36-29(45)23-8-7-21-22(38-23)6-5-11-35-21/h5-8,11,24-28,42-44H,9-10,12-19H2,1-4H3,(H,36,45)(H,37,41)(H,46,47) HEMYHTBRAMZRSM-UHFFFAOYSA-N 778256 US20250313574, Example A-114 Myeloid cell surface antigen CD33 22.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778256 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778256&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893367 523296603 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560674 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(Br)c(O)c(Br)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H46Br2N4O12/c1-17(39)36-23-21(40)13-32(28(45)46,6-8-38-9-10-48-16-31(38)5-7-37(15-31)29(47)50-30(2,3)4)49-26(23)25(43)22(41)14-35-27(44)18-11-19(33)24(42)20(34)12-18/h11-12,21-23,25-26,40-43H,5-10,13-16H2,1-4H3,(H,35,44)(H,36,39)(H,45,46) OZLHEVCTMXPEGG-UHFFFAOYSA-N 778257 US20250313574, Example A-115 Myeloid cell surface antigen CD33 7.00 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778257 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778257&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893368 523296604 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560675 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cccc(Br)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H47BrN4O11/c1-19(38)35-24-22(39)15-32(28(43)44,47-26(24)25(41)23(40)16-34-27(42)20-6-5-7-21(33)14-20)9-11-37-12-13-46-18-31(37)8-10-36(17-31)29(45)48-30(2,3)4/h5-7,14,22-26,39-41H,8-13,15-18H2,1-4H3,(H,34,42)(H,35,38)(H,43,44) ZMSHVORURSFFNK-UHFFFAOYSA-N 778258 US20250313574, Example A-116 Myeloid cell surface antigen CD33 42.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778258 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778258&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893369 523296605 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560676 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O12/c1-19-14-21(6-7-22(19)39)28(43)34-16-24(41)26(42)27-25(35-20(2)38)23(40)15-33(48-27,29(44)45)9-11-37-12-13-47-18-32(37)8-10-36(17-32)30(46)49-31(3,4)5/h6-7,14,23-27,39-42H,8-13,15-18H2,1-5H3,(H,34,43)(H,35,38)(H,44,45) NTQRMEREWBXPMP-UHFFFAOYSA-N 778259 US20250313574, Example A-117 Myeloid cell surface antigen CD33 28.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778259 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778259&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893370 523296606 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560677 COc1c(C)cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)cc1C InChI=1S/C35H54N4O12/c1-20-14-23(15-21(2)28(20)48-7)30(44)36-17-25(42)27(43)29-26(37-22(3)40)24(41)16-35(50-29,31(45)46)9-11-39-12-13-49-19-34(39)8-10-38(18-34)32(47)51-33(4,5)6/h14-15,24-27,29,41-43H,8-13,16-19H2,1-7H3,(H,36,44)(H,37,40)(H,45,46) DKRJLIZZTIFUEW-UHFFFAOYSA-N 778260 US20250313574, Example A-118 Myeloid cell surface antigen CD33 60.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778260 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778260&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893371 523296607 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560678 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(N)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H53N5O11/c1-19-13-22(14-20(2)25(19)35)29(44)36-16-24(42)27(43)28-26(37-21(3)40)23(41)15-34(49-28,30(45)46)8-10-39-11-12-48-18-33(39)7-9-38(17-33)31(47)50-32(4,5)6/h13-14,23-24,26-28,41-43H,7-12,15-18,35H2,1-6H3,(H,36,44)(H,37,40)(H,45,46) URCUGEPXCZOCLO-UHFFFAOYSA-N 778261 US20250313574, Example A-119 Myeloid cell surface antigen CD33 17.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778261 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778261&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893372 523296608 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560679 COc1ccc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)cc1OC InChI=1S/C34H52N4O13/c1-20(39)36-26-22(40)16-34(30(44)45,10-12-38-13-14-49-19-33(38)9-11-37(18-33)31(46)51-32(2,3)4)50-28(26)27(42)23(41)17-35-29(43)21-7-8-24(47-5)25(15-21)48-6/h7-8,15,22-23,26-28,40-42H,9-14,16-19H2,1-6H3,(H,35,43)(H,36,39)(H,44,45) XXIAFOOVEJITGK-UHFFFAOYSA-N 778262 US20250313574, Example A-120 Myeloid cell surface antigen CD33 40.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778262 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778262&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893373 523296609 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560680 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3occc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H48N4O12/c1-20(39)36-26-23(40)16-34(30(44)45,9-11-38-12-14-47-19-33(38)8-10-37(18-33)31(46)50-32(2,3)4)49-28(26)27(42)24(41)17-35-29(43)22-5-6-25-21(15-22)7-13-48-25/h5-7,13,15,23-24,26-28,40-42H,8-12,14,16-19H2,1-4H3,(H,35,43)(H,36,39)(H,44,45) LVLSITGXBMUDNZ-UHFFFAOYSA-N 778263 US20250313574, Example A-121 Myeloid cell surface antigen CD33 29.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778263 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778263&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893374 523296610 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560681 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc3ncccn3n2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H47N7O11/c1-19(40)35-24-21(41)15-32(28(45)46,7-11-38-12-13-48-18-31(38)6-10-37(17-31)29(47)50-30(2,3)4)49-26(24)25(43)22(42)16-34-27(44)20-14-23-33-8-5-9-39(23)36-20/h5,8-9,14,21-22,24-26,41-43H,6-7,10-13,15-18H2,1-4H3,(H,34,44)(H,35,40)(H,45,46) WKTCSQOVZYYNCX-UHFFFAOYSA-N 778264 US20250313574, Example A-122 Myeloid cell surface antigen CD33 32.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778264 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778264&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893375 523296611 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560682 COc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)cc(OC)c1O InChI=1S/C34H52N4O14/c1-19(39)36-25-21(40)15-34(30(45)46,8-10-38-11-12-50-18-33(38)7-9-37(17-33)31(47)52-32(2,3)4)51-28(25)26(42)22(41)16-35-29(44)20-13-23(48-5)27(43)24(14-20)49-6/h13-14,21-22,25-26,28,40-43H,7-12,15-18H2,1-6H3,(H,35,44)(H,36,39)(H,45,46) XKJANIDUHWFTSC-UHFFFAOYSA-N 778265 US20250313574, Example A-123 Myeloid cell surface antigen CD33 68.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778265 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778265&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893376 523296612 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560683 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3c(cnn3C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N6O11/c1-20(41)37-26-24(42)15-34(30(46)47,9-11-40-12-13-49-19-33(40)8-10-39(18-33)31(48)51-32(2,3)4)50-28(26)27(44)25(43)17-35-29(45)21-6-7-23-22(14-21)16-36-38(23)5/h6-7,14,16,24-28,42-44H,8-13,15,17-19H2,1-5H3,(H,35,45)(H,37,41)(H,46,47) MPXWSFDESPRSKL-UHFFFAOYSA-N 778266 US20250313574, Example A-124 Myeloid cell surface antigen CD33 28.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778266 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778266&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893377 523296613 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560684 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3[nH]nc(C)c3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N6O11/c1-19-22-14-21(6-7-23(22)38-37-19)29(45)35-16-25(43)27(44)28-26(36-20(2)41)24(42)15-34(50-28,30(46)47)9-11-40-12-13-49-18-33(40)8-10-39(17-33)31(48)51-32(3,4)5/h6-7,14,24-28,42-44H,8-13,15-18H2,1-5H3,(H,35,45)(H,36,41)(H,37,38)(H,46,47) SVUVEKOZRYEQQA-UHFFFAOYSA-N 778267 US20250313574, Example A-125 Myeloid cell surface antigen CD33 23.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778267 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778267&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893378 523296614 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560685 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cnc3[nH]ncc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H47N7O11/c1-18(40)36-23-21(41)12-32(28(45)46,6-8-39-9-10-48-17-31(39)5-7-38(16-31)29(47)50-30(2,3)4)49-25(23)24(43)22(42)15-34-27(44)20-11-19-14-35-37-26(19)33-13-20/h11,13-14,21-25,41-43H,5-10,12,15-17H2,1-4H3,(H,34,44)(H,36,40)(H,45,46)(H,33,35,37) ZTKXRCMDVHSZCB-UHFFFAOYSA-N 778268 US20250313574, Example A-126 Myeloid cell surface antigen CD33 50.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778268 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778268&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893379 523296615 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560686 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cnc3[nH]nc(C)c3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H49N7O11/c1-18-21-12-20(14-34-27(21)38-37-18)28(45)35-15-23(43)25(44)26-24(36-19(2)41)22(42)13-33(50-26,29(46)47)7-9-40-10-11-49-17-32(40)6-8-39(16-32)30(48)51-31(3,4)5/h12,14,22-26,42-44H,6-11,13,15-17H2,1-5H3,(H,35,45)(H,36,41)(H,46,47)(H,34,37,38) YARWMKHAXNFHLQ-UHFFFAOYSA-N 778269 US20250313574, Example A-127 Myeloid cell surface antigen CD33 59.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778269 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778269&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893380 523296616 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560687 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3[nH]nc(F)c3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H47FN6O11/c1-18(41)36-24-22(42)14-33(29(46)47,8-10-40-11-12-49-17-32(40)7-9-39(16-32)30(48)51-31(2,3)4)50-26(24)25(44)23(43)15-35-28(45)19-5-6-21-20(13-19)27(34)38-37-21/h5-6,13,22-26,42-44H,7-12,14-17H2,1-4H3,(H,35,45)(H,36,41)(H,37,38)(H,46,47) NJPOMTKGZLVETH-UHFFFAOYSA-N 778270 US20250313574, Example A-128 Myeloid cell surface antigen CD33 50.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778270 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778270&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893381 523296617 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560688 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3[nH]ccc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H49N5O11/c1-20(40)37-26-24(41)16-34(30(45)46,9-12-39-13-14-48-19-33(39)8-11-38(18-33)31(47)50-32(2,3)4)49-28(26)27(43)25(42)17-36-29(44)22-5-6-23-21(15-22)7-10-35-23/h5-7,10,15,24-28,35,41-43H,8-9,11-14,16-19H2,1-4H3,(H,36,44)(H,37,40)(H,45,46) BHUXZGYGWVIVIA-UHFFFAOYSA-N 778271 US20250313574, Example A-129 Myeloid cell surface antigen CD33 10.00 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778271 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778271&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893382 523296618 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560689 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c3[nH]ncc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N6O11/c1-19-12-21(13-22-15-36-38-25(19)22)29(45)35-16-24(43)27(44)28-26(37-20(2)41)23(42)14-34(50-28,30(46)47)7-9-40-10-11-49-18-33(40)6-8-39(17-33)31(48)51-32(3,4)5/h12-13,15,23-24,26-28,42-44H,6-11,14,16-18H2,1-5H3,(H,35,45)(H,36,38)(H,37,41)(H,46,47) JJDLXXGAJZVBRG-UHFFFAOYSA-N 778272 US20250313574, Example A-130 Myeloid cell surface antigen CD33 9.00 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778272 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778272&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893364 523296619 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560690 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3sc(C)nc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H49N5O11S/c1-19(40)36-26-23(41)15-34(30(45)46,9-11-39-12-13-48-18-33(39)8-10-38(17-33)31(47)50-32(3,4)5)49-28(26)27(43)24(42)16-35-29(44)21-6-7-25-22(14-21)37-20(2)51-25/h6-7,14,23-24,26-28,41-43H,8-13,15-18H2,1-5H3,(H,35,44)(H,36,40)(H,45,46) KYWWUCVGOIPVDP-UHFFFAOYSA-N 778273 US20250313574, Example A-131 Myeloid cell surface antigen CD33 24.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778273 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778273&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893383 523296620 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560691 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(F)c(Br)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H46BrFN4O11/c1-18(39)36-24-22(40)14-32(28(44)45,48-26(24)25(42)23(41)15-35-27(43)19-5-6-21(34)20(33)13-19)8-10-38-11-12-47-17-31(38)7-9-37(16-31)29(46)49-30(2,3)4/h5-6,13,22-26,40-42H,7-12,14-17H2,1-4H3,(H,35,43)(H,36,39)(H,44,45) CXYXWBSJSNEHCU-UHFFFAOYSA-N 778274 US20250313574, Example A-132 Myeloid cell surface antigen CD33 51.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778274 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778274&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893384 523296621 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560692 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(Br)[nH]n2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C29H45BrN6O11/c1-16(37)32-21-18(38)12-29(25(42)43,46-23(21)22(40)19(39)13-31-24(41)17-11-20(30)34-33-17)6-8-36-9-10-45-15-28(36)5-7-35(14-28)26(44)47-27(2,3)4/h11,18-19,21-23,38-40H,5-10,12-15H2,1-4H3,(H,31,41)(H,32,37)(H,33,34)(H,42,43) XTTNXLIWUBETRF-UHFFFAOYSA-N 778275 US20250313574, Example A-133 Myeloid cell surface antigen CD33 46.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778275 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778275&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893385 523296622 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560693 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c3[nH]c(CO)cc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C36H53N5O12/c1-20-12-23(13-22-14-24(17-42)39-27(20)22)31(47)37-16-26(45)29(46)30-28(38-21(2)43)25(44)15-36(52-30,32(48)49)7-9-41-10-11-51-19-35(41)6-8-40(18-35)33(50)53-34(3,4)5/h12-14,25-26,28-30,39,42,44-46H,6-11,15-19H2,1-5H3,(H,37,47)(H,38,43)(H,48,49) ZXBRDNIOMIVKOG-UHFFFAOYSA-N 778276 US20250313574, Example A-134 Myeloid cell surface antigen CD33 14.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778276 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778276&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893386 523296623 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560694 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3[nH]cnc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H48N6O11/c1-19(40)37-25-23(41)14-33(29(45)46,8-10-39-11-12-48-17-32(39)7-9-38(16-32)30(47)50-31(2,3)4)49-27(25)26(43)24(42)15-34-28(44)20-5-6-21-22(13-20)36-18-35-21/h5-6,13,18,23-27,41-43H,7-12,14-17H2,1-4H3,(H,34,44)(H,35,36)(H,37,40)(H,45,46) AJBHBRFKKVUZNW-UHFFFAOYSA-N 778277 US20250313574, Example A-135 Myeloid cell surface antigen CD33 101 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778277 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778277&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893387 523296624 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560695 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cn(C)nc2C)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C31H50N6O11/c1-18-20(15-35(6)34-18)26(42)32-14-22(40)24(41)25-23(33-19(2)38)21(39)13-31(47-25,27(43)44)8-10-37-11-12-46-17-30(37)7-9-36(16-30)28(45)48-29(3,4)5/h15,21-25,39-41H,7-14,16-17H2,1-6H3,(H,32,42)(H,33,38)(H,43,44) UKKPJHCWFYUGGK-UHFFFAOYSA-N 778278 US20250313574, Example A-136 Myeloid cell surface antigen CD33 440 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778278 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778278&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893388 523296625 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560696 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3occc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H48N4O12/c1-20(39)36-26-23(40)16-34(30(44)45,9-11-38-12-14-47-19-33(38)8-10-37(18-33)31(46)50-32(2,3)4)49-28(26)27(42)24(41)17-35-29(43)22-5-6-25-21(15-22)7-13-48-25/h5-7,13,15,23-24,26-28,40-42H,8-12,14,16-19H2,1-4H3,(H,35,43)(H,36,39)(H,44,45) LVLSITGXBMUDNZ-UHFFFAOYSA-N 778279 US20250313574, Example A-137 Myeloid cell surface antigen CD33 76.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778279 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778279&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893374 523296626 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560697 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3c(=O)n(C)cnc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H50N6O12/c1-20(42)38-26-24(43)15-35(31(48)49,9-11-41-12-13-51-18-34(41)8-10-40(17-34)32(50)53-33(2,3)4)52-28(26)27(45)25(44)16-36-29(46)21-6-7-22-23(14-21)37-19-39(5)30(22)47/h6-7,14,19,24-28,43-45H,8-13,15-18H2,1-5H3,(H,36,46)(H,38,42)(H,48,49) WZEPERBIRAAWJI-UHFFFAOYSA-N 778280 US20250313574, Example A-138 Myeloid cell surface antigen CD33 600 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778280 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778280&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893389 523296627 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560698 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2c[nH]c(C)n2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C30H48N6O11/c1-17-31-13-19(33-17)25(41)32-14-21(39)23(40)24-22(34-18(2)37)20(38)12-30(46-24,26(42)43)7-9-36-10-11-45-16-29(36)6-8-35(15-29)27(44)47-28(3,4)5/h13,20-24,38-40H,6-12,14-16H2,1-5H3,(H,31,33)(H,32,41)(H,34,37)(H,42,43) IJMYSEAHCWYHSC-UHFFFAOYSA-N 778281 US20250313574, Example A-139 Myeloid cell surface antigen CD33 610 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778281 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778281&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893390 523296628 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560699 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2nc(C)oc2C)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C31H49N5O12/c1-17-22(34-19(3)46-17)26(41)32-14-21(39)24(40)25-23(33-18(2)37)20(38)13-31(47-25,27(42)43)8-10-36-11-12-45-16-30(36)7-9-35(15-30)28(44)48-29(4,5)6/h20-21,23-25,38-40H,7-16H2,1-6H3,(H,32,41)(H,33,37)(H,42,43) LXDIPMRMJZKCPX-UHFFFAOYSA-N 778282 US20250313574, Example A-140 Myeloid cell surface antigen CD33 350 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778282 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778282&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893391 523296629 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560700 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(C(N)=O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H53N5O12/c1-19-13-22(14-20(2)25(19)29(36)45)30(46)37-16-24(43)27(44)28-26(38-21(3)41)23(42)15-35(51-28,31(47)48)8-10-40-11-12-50-18-34(40)7-9-39(17-34)32(49)52-33(4,5)6/h13-14,23-24,26-28,42-44H,7-12,15-18H2,1-6H3,(H2,36,45)(H,37,46)(H,38,41)(H,47,48) XOQPPAQOQAQNHR-UHFFFAOYSA-N 778283 US20250313574, Example A-141 Myeloid cell surface antigen CD33 350 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778283 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778283&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893392 523296630 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560701 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(-c3ncn[nH]3)cc2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H49N7O11/c1-20(42)38-25-23(43)15-34(30(47)48,10-12-41-13-14-50-18-33(41)9-11-40(17-33)31(49)52-32(2,3)4)51-27(25)26(45)24(44)16-35-29(46)22-7-5-21(6-8-22)28-36-19-37-39-28/h5-8,19,23-27,43-45H,9-18H2,1-4H3,(H,35,46)(H,38,42)(H,47,48)(H,36,37,39) RIQFTORLSHJSAV-UHFFFAOYSA-N 778284 US20250313574, Example A-142 Myeloid cell surface antigen CD33 340 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778284 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778284&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893393 523296631 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560702 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(N3CCN(C)CC3)cc2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C37H58N6O11/c1-24(44)39-29-27(45)20-37(33(49)50,11-13-43-18-19-52-23-36(43)10-12-42(22-36)34(51)54-35(2,3)4)53-31(29)30(47)28(46)21-38-32(48)25-6-8-26(9-7-25)41-16-14-40(5)15-17-41/h6-9,27-31,45-47H,10-23H2,1-5H3,(H,38,48)(H,39,44)(H,49,50) KUMSZIJSGUHWGQ-UHFFFAOYSA-N 778285 US20250313574, Example A-143 Myeloid cell surface antigen CD33 334 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778285 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778285&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893394 523296632 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560703 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1ccc(C(F)(F)F)c(C)c1 InChI=1S/C34H49F3N4O11/c1-19-14-21(6-7-22(19)34(35,36)37)28(46)38-16-24(44)26(45)27-25(39-20(2)42)23(43)15-33(51-27,29(47)48)9-11-41-12-13-50-18-32(41)8-10-40(17-32)30(49)52-31(3,4)5/h6-7,14,23-27,43-45H,8-13,15-18H2,1-5H3,(H,38,46)(H,39,42)(H,47,48) IXNGWYLKOKULTO-UHFFFAOYSA-N 778286 US20250313574, Example A-144 Myeloid cell surface antigen CD33 230 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778286 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778286&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893395 523296633 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560704 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1ccc(C)c(C(F)(F)F)c1 InChI=1S/C34H49F3N4O11/c1-19-6-7-21(14-22(19)34(35,36)37)28(46)38-16-24(44)26(45)27-25(39-20(2)42)23(43)15-33(51-27,29(47)48)9-11-41-12-13-50-18-32(41)8-10-40(17-32)30(49)52-31(3,4)5/h6-7,14,23-27,43-45H,8-13,15-18H2,1-5H3,(H,38,46)(H,39,42)(H,47,48) SYOPJRHTCIMGPT-UHFFFAOYSA-N 778287 US20250313574, Example A-145 Myeloid cell surface antigen CD33 610 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778287 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778287&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893396 523296634 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560705 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1ccc(C(F)(F)F)c(O)c1 InChI=1S/C33H47F3N4O12/c1-18(41)38-24-22(43)14-32(28(47)48,8-10-40-11-12-50-17-31(40)7-9-39(16-31)29(49)52-30(2,3)4)51-26(24)25(45)23(44)15-37-27(46)19-5-6-20(21(42)13-19)33(34,35)36/h5-6,13,22-26,42-45H,7-12,14-17H2,1-4H3,(H,37,46)(H,38,41)(H,47,48) RVHYTAHQTWWWLX-UHFFFAOYSA-N 778288 US20250313574, Example A-146 Myeloid cell surface antigen CD33 262 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778288 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778288&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893397 523296635 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560706 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1ccc(O)c(C(F)(F)F)c1 InChI=1S/C33H47F3N4O12/c1-18(41)38-24-22(43)14-32(28(47)48,8-10-40-11-12-50-17-31(40)7-9-39(16-31)29(49)52-30(2,3)4)51-26(24)25(45)23(44)15-37-27(46)19-5-6-21(42)20(13-19)33(34,35)36/h5-6,13,22-26,42-45H,7-12,14-17H2,1-4H3,(H,37,46)(H,38,41)(H,47,48) CYDQCJUNDKLDBC-UHFFFAOYSA-N 778289 US20250313574, Example A-147 Myeloid cell surface antigen CD33 127 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778289 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778289&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893398 523296636 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560707 COc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)cc(OC)c1OC InChI=1S/C35H54N4O14/c1-20(40)37-26-22(41)16-35(31(45)46,9-11-39-12-13-51-19-34(39)8-10-38(18-34)32(47)53-33(2,3)4)52-29(26)27(43)23(42)17-36-30(44)21-14-24(48-5)28(50-7)25(15-21)49-6/h14-15,22-23,26-27,29,41-43H,8-13,16-19H2,1-7H3,(H,36,44)(H,37,40)(H,45,46) XDMHPYCYFUDTGS-UHFFFAOYSA-N 778290 US20250313574, Example A-148 Myeloid cell surface antigen CD33 197 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778290 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778290&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893399 523296637 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560708 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(C)c(F)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H49FN4O11/c1-19-6-7-21(14-22(19)34)28(43)35-16-24(41)26(42)27-25(36-20(2)39)23(40)15-33(48-27,29(44)45)9-11-38-12-13-47-18-32(38)8-10-37(17-32)30(46)49-31(3,4)5/h6-7,14,23-27,40-42H,8-13,15-18H2,1-5H3,(H,35,43)(H,36,39)(H,44,45) JVQBFMAJGPTSJZ-UHFFFAOYSA-N 778291 US20250313574, Example A-149 Myeloid cell surface antigen CD33 133 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778291 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778291&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893400 523296638 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560709 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3c(c2)N(C)C(=O)CO3)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H51N5O13/c1-20(41)37-27-23(42)15-35(31(47)48,9-11-40-12-13-50-19-34(40)8-10-39(18-34)32(49)53-33(2,3)4)52-29(27)28(45)24(43)16-36-30(46)21-6-7-25-22(14-21)38(5)26(44)17-51-25/h6-7,14,23-24,27-29,42-43,45H,8-13,15-19H2,1-5H3,(H,36,46)(H,37,41)(H,47,48) CFVCSGKZTBKSGB-UHFFFAOYSA-N 778292 US20250313574, Example A-150 Myeloid cell surface antigen CD33 219 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778292 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778292&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893401 523296639 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560710 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3cn[nH]c3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H48N6O11/c1-19(40)36-25-23(41)14-33(29(45)46,8-10-39-11-12-48-18-32(39)7-9-38(17-32)30(47)50-31(2,3)4)49-27(25)26(43)24(42)16-34-28(44)20-5-6-21-15-35-37-22(21)13-20/h5-6,13,15,23-27,41-43H,7-12,14,16-18H2,1-4H3,(H,34,44)(H,35,37)(H,36,40)(H,45,46) YYYIQZAQKDOUJM-UHFFFAOYSA-N 778293 US20250313574, Example A-151 Myeloid cell surface antigen CD33 206 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778293 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778293&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893402 523296640 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560711 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(O)c(NC=O)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H49N5O13/c1-19(40)36-25-23(42)14-33(29(46)47,8-10-38-11-12-49-17-32(38)7-9-37(16-32)30(48)51-31(2,3)4)50-27(25)26(44)24(43)15-34-28(45)20-5-6-22(41)21(13-20)35-18-39/h5-6,13,18,23-27,41-44H,7-12,14-17H2,1-4H3,(H,34,45)(H,35,39)(H,36,40)(H,46,47) XIERSHGTTKPFRL-UHFFFAOYSA-N 778294 US20250313574, Example A-152 Myeloid cell surface antigen CD33 510 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778294 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778294&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893403 523296641 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560712 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3nsnc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H46N6O11S/c1-18(39)34-24-22(40)14-32(28(44)45,8-10-38-11-12-47-17-31(38)7-9-37(16-31)29(46)49-30(2,3)4)48-26(24)25(42)23(41)15-33-27(43)19-5-6-20-21(13-19)36-50-35-20/h5-6,13,22-26,40-42H,7-12,14-17H2,1-4H3,(H,33,43)(H,34,39)(H,44,45) GEDADZHBGQIKFA-UHFFFAOYSA-N 778295 US20250313574, Example A-153 Myeloid cell surface antigen CD33 196 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778295 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778295&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893404 523296642 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560713 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)n(C)n2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C31H50N6O11/c1-18-13-20(34-35(18)6)26(42)32-15-22(40)24(41)25-23(33-19(2)38)21(39)14-31(47-25,27(43)44)8-10-37-11-12-46-17-30(37)7-9-36(16-30)28(45)48-29(3,4)5/h13,21-25,39-41H,7-12,14-17H2,1-6H3,(H,32,42)(H,33,38)(H,43,44) RRDWJBPIZCDMBE-UHFFFAOYSA-N 778296 US20250313574, Example A-154 Myeloid cell surface antigen CD33 137 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778296 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778296&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893405 523296643 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560714 CCc1cccc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)c1 InChI=1S/C34H52N4O11/c1-6-22-8-7-9-23(16-22)29(43)35-18-25(41)27(42)28-26(36-21(2)39)24(40)17-34(48-28,30(44)45)11-13-38-14-15-47-20-33(38)10-12-37(19-33)31(46)49-32(3,4)5/h7-9,16,24-28,40-42H,6,10-15,17-20H2,1-5H3,(H,35,43)(H,36,39)(H,44,45) NLDLCLRBQVNKGZ-UHFFFAOYSA-N 778297 US20250313574, Example A-155 Myeloid cell surface antigen CD33 200 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778297 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778297&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893406 523296644 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560715 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)[nH]n2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C30H48N6O11/c1-17-12-19(34-33-17)25(41)31-14-21(39)23(40)24-22(32-18(2)37)20(38)13-30(46-24,26(42)43)7-9-36-10-11-45-16-29(36)6-8-35(15-29)27(44)47-28(3,4)5/h12,20-24,38-40H,6-11,13-16H2,1-5H3,(H,31,41)(H,32,37)(H,33,34)(H,42,43) NRHFGXHPTZNTND-UHFFFAOYSA-N 778298 US20250313574, Example A-156 Myeloid cell surface antigen CD33 138 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778298 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778298&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893407 523296645 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560716 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(Cl)[nH]n2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C29H45ClN6O11/c1-16(37)32-21-18(38)12-29(25(42)43,46-23(21)22(40)19(39)13-31-24(41)17-11-20(30)34-33-17)6-8-36-9-10-45-15-28(36)5-7-35(14-28)26(44)47-27(2,3)4/h11,18-19,21-23,38-40H,5-10,12-15H2,1-4H3,(H,31,41)(H,32,37)(H,33,34)(H,42,43) WJALMTROODCQCM-UHFFFAOYSA-N 778299 US20250313574, Example A-157 Myeloid cell surface antigen CD33 80.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778299 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778299&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893408 523296646 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560717 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2coc(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C31H48N4O12/c1-18-12-20(15-45-18)26(40)32-14-22(38)24(39)25-23(33-19(2)36)21(37)13-31(46-25,27(41)42)7-9-35-10-11-44-17-30(35)6-8-34(16-30)28(43)47-29(3,4)5/h12,15,21-25,37-39H,6-11,13-14,16-17H2,1-5H3,(H,32,40)(H,33,36)(H,41,42) NRSJUWYEBINEMJ-UHFFFAOYSA-N 778300 US20250313574, Example A-158 Myeloid cell surface antigen CD33 133 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778300 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778300&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893409 523296647 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560718 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(Cl)c(F)c(Cl)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H45Cl2FN4O11/c1-17(40)37-24-21(41)13-32(28(45)46,6-8-39-9-10-48-16-31(39)5-7-38(15-31)29(47)50-30(2,3)4)49-26(24)25(43)22(42)14-36-27(44)18-11-19(33)23(35)20(34)12-18/h11-12,21-22,24-26,41-43H,5-10,13-16H2,1-4H3,(H,36,44)(H,37,40)(H,45,46) NVKVKHIEUVRQKA-UHFFFAOYSA-N 778301 US20250313574, Example A-159 Myeloid cell surface antigen CD33 238 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778301 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778301&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893410 523296648 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560719 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)oc2C(F)(F)F)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H47F3N4O12/c1-17-12-19(25(49-17)32(33,34)35)26(44)36-14-21(42)23(43)24-22(37-18(2)40)20(41)13-31(50-24,27(45)46)7-9-39-10-11-48-16-30(39)6-8-38(15-30)28(47)51-29(3,4)5/h12,20-24,41-43H,6-11,13-16H2,1-5H3,(H,36,44)(H,37,40)(H,45,46) OTIJRGMELOMSGP-UHFFFAOYSA-N 778302 US20250313574, Example A-160 Myeloid cell surface antigen CD33 680 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778302 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778302&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893411 523296649 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560720 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cn[nH]c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C29H46N6O11/c1-17(36)33-21-19(37)11-29(25(41)42,45-23(21)22(39)20(38)14-30-24(40)18-12-31-32-13-18)6-8-35-9-10-44-16-28(35)5-7-34(15-28)26(43)46-27(2,3)4/h12-13,19-23,37-39H,5-11,14-16H2,1-4H3,(H,30,40)(H,31,32)(H,33,36)(H,41,42) WRDFVBSZHDUQOM-UHFFFAOYSA-N 778303 US20250313574, Example A-161 Myeloid cell surface antigen CD33 1080 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778303 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778303&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893412 523296650 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560721 CCC/C(C)=C/C(=O)NC[C@@H](O)[C@@H](O)[C@@H]1O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@H](O)[C@H]1NC(C)=O InChI=1S/C32H54N4O11/c1-7-8-20(2)15-24(40)33-17-23(39)26(41)27-25(34-21(3)37)22(38)16-32(46-27,28(42)43)10-12-36-13-14-45-19-31(36)9-11-35(18-31)29(44)47-30(4,5)6/h15,22-23,25-27,38-39,41H,7-14,16-19H2,1-6H3,(H,33,40)(H,34,37)(H,42,43) KDLYQSHMIWOMHG-UHFFFAOYSA-N 778304 US20250313574, Example A-162 Myeloid cell surface antigen CD33 4210 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778304 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778304&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893413 523296651 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560722 C/C=C/C=C/C(=O)NC[C@@H](O)[C@@H](O)[C@@H]1O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@H](O)[C@H]1NC(C)=O InChI=1S/C31H50N4O11/c1-6-7-8-9-23(39)32-17-22(38)25(40)26-24(33-20(2)36)21(37)16-31(45-26,27(41)42)11-13-35-14-15-44-19-30(35)10-12-34(18-30)28(43)46-29(3,4)5/h6-9,21-22,24-26,37-38,40H,10-19H2,1-5H3,(H,32,39)(H,33,36)(H,41,42) DQLZSIQBGFLOCF-UHFFFAOYSA-N 778305 US20250313574, Example A-163 Myeloid cell surface antigen CD33 700 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778305 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778305&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893414 523296652 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560723 CNC(=O)c1c(C)cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)cc1C InChI=1S/C36H55N5O12/c1-20-14-23(15-21(2)26(20)31(47)37-7)30(46)38-17-25(44)28(45)29-27(39-22(3)42)24(43)16-36(52-29,32(48)49)9-11-41-12-13-51-19-35(41)8-10-40(18-35)33(50)53-34(4,5)6/h14-15,24-25,27-29,43-45H,8-13,16-19H2,1-7H3,(H,37,47)(H,38,46)(H,39,42)(H,48,49) WZNSOOXVLCEZRQ-UHFFFAOYSA-N 778306 US20250313574, Example A-164 Myeloid cell surface antigen CD33 1560 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778306 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778306&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893415 523296653 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560724 COc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)ccc1C#N InChI=1S/C34H49N5O12/c1-20(40)37-26-23(41)15-34(30(45)46,9-11-39-12-13-49-19-33(39)8-10-38(18-33)31(47)51-32(2,3)4)50-28(26)27(43)24(42)17-36-29(44)21-6-7-22(16-35)25(14-21)48-5/h6-7,14,23-24,26-28,41-43H,8-13,15,17-19H2,1-5H3,(H,36,44)(H,37,40)(H,45,46) KSZBSSDOQYVSJS-UHFFFAOYSA-N 778307 US20250313574, Example A-165 Myeloid cell surface antigen CD33 1140 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778307 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778307&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893416 523296654 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560725 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1cc(F)c(C(F)(F)F)c(F)c1 InChI=1S/C33H45F5N4O11/c1-17(43)40-24-21(44)13-32(28(48)49,6-8-42-9-10-51-16-31(42)5-7-41(15-31)29(50)53-30(2,3)4)52-26(24)25(46)22(45)14-39-27(47)18-11-19(34)23(20(35)12-18)33(36,37)38/h11-12,21-22,24-26,44-46H,5-10,13-16H2,1-4H3,(H,39,47)(H,40,43)(H,48,49) MQPFDNVZECXQQV-UHFFFAOYSA-N 778308 US20250313574, Example A-166 Myeloid cell surface antigen CD33 4000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778308 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778308&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893417 523296655 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560726 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1ccc(C(F)(F)F)c(C(F)(F)F)c1 InChI=1S/C34H46F6N4O11/c1-18(45)42-24-22(46)14-32(28(50)51,8-10-44-11-12-53-17-31(44)7-9-43(16-31)29(52)55-30(2,3)4)54-26(24)25(48)23(47)15-41-27(49)19-5-6-20(33(35,36)37)21(13-19)34(38,39)40/h5-6,13,22-26,46-48H,7-12,14-17H2,1-4H3,(H,41,49)(H,42,45)(H,50,51) RSGFAKGCOHXEHL-UHFFFAOYSA-N 778309 US20250313574, Example A-167 Myeloid cell surface antigen CD33 3340 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778309 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778309&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893418 523296656 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560727 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 InChI=1S/C34H46F6N4O11/c1-18(45)42-24-22(46)14-32(28(50)51,6-8-44-9-10-53-17-31(44)5-7-43(16-31)29(52)55-30(2,3)4)54-26(24)25(48)23(47)15-41-27(49)19-11-20(33(35,36)37)13-21(12-19)34(38,39)40/h11-13,22-26,46-48H,5-10,14-17H2,1-4H3,(H,41,49)(H,42,45)(H,50,51) LPPSRUWNZLJZML-UHFFFAOYSA-N 778310 US20250313574, Example A-168 Myeloid cell surface antigen CD33 1970 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778310 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778310&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893419 523296657 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560728 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1cccc(SC(F)(F)F)c1 InChI=1S/C33H47F3N4O11S/c1-19(41)38-24-22(42)15-32(28(46)47,9-11-40-12-13-49-18-31(40)8-10-39(17-31)29(48)51-30(2,3)4)50-26(24)25(44)23(43)16-37-27(45)20-6-5-7-21(14-20)52-33(34,35)36/h5-7,14,22-26,42-44H,8-13,15-18H2,1-4H3,(H,37,45)(H,38,41)(H,46,47) CYFJEDXGGFSQRA-UHFFFAOYSA-N 778311 US20250313574, Example A-169 Myeloid cell surface antigen CD33 4720 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778311 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778311&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893420 523296658 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560729 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(=O)n(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H49N5O12/c1-19(38)34-24-21(39)14-32(28(44)45,48-26(24)25(42)22(40)15-33-27(43)20-6-7-23(41)35(5)16-20)9-11-37-12-13-47-18-31(37)8-10-36(17-31)29(46)49-30(2,3)4/h6-7,16,21-22,24-26,39-40,42H,8-15,17-18H2,1-5H3,(H,33,43)(H,34,38)(H,44,45) VXPWBWNSCCMXKX-UHFFFAOYSA-N 778312 US20250313574, Example A-170 Myeloid cell surface antigen CD33 3870 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778312 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778312&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893421 523296659 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560730 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(=O)[nH]c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C31H47N5O12/c1-18(37)34-23-20(38)13-31(27(43)44,47-25(23)24(41)21(39)15-33-26(42)19-5-6-22(40)32-14-19)8-10-36-11-12-46-17-30(36)7-9-35(16-30)28(45)48-29(2,3)4/h5-6,14,20-21,23-25,38-39,41H,7-13,15-17H2,1-4H3,(H,32,40)(H,33,42)(H,34,37)(H,43,44) JHXGFHXNBHDIQG-UHFFFAOYSA-N 778313 US20250313574, Example A-171 Myeloid cell surface antigen CD33 10300 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778313 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778313&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893422 523296660 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560731 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(Br)ccc2F)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H46BrFN4O11/c1-18(39)36-24-22(40)14-32(28(44)45,48-26(24)25(42)23(41)15-35-27(43)20-13-19(33)5-6-21(20)34)8-10-38-11-12-47-17-31(38)7-9-37(16-31)29(46)49-30(2,3)4/h5-6,13,22-26,40-42H,7-12,14-17H2,1-4H3,(H,35,43)(H,36,39)(H,44,45) BOBGFFDESQKHKY-UHFFFAOYSA-N 778314 US20250313574, Example A-172 Myeloid cell surface antigen CD33 820 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778314 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778314&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893423 523296661 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560732 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cn[nH]c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C29H46N6O11/c1-17(36)33-21-19(37)11-29(25(41)42,45-23(21)22(39)20(38)14-30-24(40)18-12-31-32-13-18)6-8-35-9-10-44-16-28(35)5-7-34(15-28)26(43)46-27(2,3)4/h12-13,19-23,37-39H,5-11,14-16H2,1-4H3,(H,30,40)(H,31,32)(H,33,36)(H,41,42) WRDFVBSZHDUQOM-UHFFFAOYSA-N 778315 US20250313574, Example A-173 Myeloid cell surface antigen CD33 1080 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778315 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778315&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893412 523296662 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560733 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1cn(C)nc1C(F)(F)F InChI=1S/C31H47F3N6O11/c1-17(41)36-21-19(42)12-30(26(46)47,7-9-40-10-11-49-16-29(40)6-8-39(15-29)27(48)51-28(2,3)4)50-23(21)22(44)20(43)13-35-25(45)18-14-38(5)37-24(18)31(32,33)34/h14,19-23,42-44H,6-13,15-16H2,1-5H3,(H,35,45)(H,36,41)(H,46,47) MDBLYUYNZXGXSZ-UHFFFAOYSA-N 778316 US20250313574, Example A-174 Myeloid cell surface antigen CD33 1170 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778316 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778316&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893424 523296663 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560734 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)OC1C(O)C(O)CNC(=O)c1c[nH]nc1C(F)(F)F InChI=1S/C30H45F3N6O11/c1-16(40)36-20-18(41)11-29(25(45)46,6-8-39-9-10-48-15-28(39)5-7-38(14-28)26(47)50-27(2,3)4)49-22(20)21(43)19(42)13-34-24(44)17-12-35-37-23(17)30(31,32)33/h12,18-22,41-43H,5-11,13-15H2,1-4H3,(H,34,44)(H,35,37)(H,36,40)(H,45,46) XJIAHTXEXPIVPU-UHFFFAOYSA-N 778317 US20250313574, Example A-175 Myeloid cell surface antigen CD33 4110 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778317 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778317&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893425 523296664 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560735 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)/C=C/c2cn[nH]c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C31H48N6O11/c1-19(38)35-24-21(39)13-31(27(43)44,47-26(24)25(42)22(40)16-32-23(41)6-5-20-14-33-34-15-20)8-10-37-11-12-46-18-30(37)7-9-36(17-30)28(45)48-29(2,3)4/h5-6,14-15,21-22,24-26,39-40,42H,7-13,16-18H2,1-4H3,(H,32,41)(H,33,34)(H,35,38)(H,43,44) OLHDAUZHUPNROB-UHFFFAOYSA-N 778318 US20250313574, Example A-176 Myeloid cell surface antigen CD33 650 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778318 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778318&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893426 523296665 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560736 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cnn(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C30H48N6O11/c1-18(37)33-22-20(38)12-30(26(42)43,46-24(22)23(40)21(39)14-31-25(41)19-13-32-34(5)15-19)7-9-36-10-11-45-17-29(36)6-8-35(16-29)27(44)47-28(2,3)4/h13,15,20-24,38-40H,6-12,14,16-17H2,1-5H3,(H,31,41)(H,33,37)(H,42,43) JAZYZCNTFUAGBL-UHFFFAOYSA-N 778319 US20250313574, Example A-177 Myeloid cell surface antigen CD33 670 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778319 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778319&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893427 523296666 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560737 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc3[nH]nnc3c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H47N7O11/c1-18(40)34-24-22(41)14-32(28(45)46,8-10-39-11-12-48-17-31(39)7-9-38(16-31)29(47)50-30(2,3)4)49-26(24)25(43)23(42)15-33-27(44)19-5-6-20-21(13-19)36-37-35-20/h5-6,13,22-26,41-43H,7-12,14-17H2,1-4H3,(H,33,44)(H,34,40)(H,45,46)(H,35,36,37) ZFCAYYZQLZQANF-UHFFFAOYSA-N 778320 US20250313574, Example A-178 Myeloid cell surface antigen CD33 146 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778320 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778320&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893428 523296667 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560738 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(-c3csc(C)n3)on2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H48N6O12S/c1-18(40)35-25-22(41)13-33(29(45)46,7-9-39-10-11-48-17-32(39)6-8-38(16-32)30(47)50-31(3,4)5)49-27(25)26(43)23(42)14-34-28(44)20-12-24(51-37-20)21-15-52-19(2)36-21/h12,15,22-23,25-27,41-43H,6-11,13-14,16-17H2,1-5H3,(H,34,44)(H,35,40)(H,45,46) FHBLFNWBOPZCLO-UHFFFAOYSA-N 778321 US20250313574, Example A-179 Myeloid cell surface antigen CD33 217 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778321 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778321&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893429 523296668 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560739 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(C)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O11/c1-20-7-8-23(15-21(20)2)29(43)35-17-25(41)27(42)28-26(36-22(3)39)24(40)16-34(48-28,30(44)45)10-12-38-13-14-47-19-33(38)9-11-37(18-33)31(46)49-32(4,5)6/h7-8,15,24-28,40-42H,9-14,16-19H2,1-6H3,(H,35,43)(H,36,39)(H,44,45) CSHNKCYCJQJOKL-UHFFFAOYSA-N 778322 US20250313574, Example A-180 Myeloid cell surface antigen CD33 74.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778322 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778322&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893430 523296669 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560740 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cccc(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O11/c1-20-7-6-8-22(15-20)28(42)34-17-24(40)26(41)27-25(35-21(2)38)23(39)16-33(47-27,29(43)44)10-12-37-13-14-46-19-32(37)9-11-36(18-32)30(45)48-31(3,4)5/h6-8,15,23-27,39-41H,9-14,16-19H2,1-5H3,(H,34,42)(H,35,38)(H,43,44) KOEKJSFMKIUDJZ-UHFFFAOYSA-N 778323 US20250313574, Example A-181 Myeloid cell surface antigen CD33 70.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778323 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778323&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893431 523296670 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560741 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cccc(Cl)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H47ClN4O11/c1-19(38)35-24-22(39)15-32(28(43)44,47-26(24)25(41)23(40)16-34-27(42)20-6-5-7-21(33)14-20)9-11-37-12-13-46-18-31(37)8-10-36(17-31)29(45)48-30(2,3)4/h5-7,14,22-26,39-41H,8-13,15-18H2,1-4H3,(H,34,42)(H,35,38)(H,43,44) XHQWIIRCGOKMML-UHFFFAOYSA-N 778324 US20250313574, Example A-182 Myeloid cell surface antigen CD33 73.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778324 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778324&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893432 523296671 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560742 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cccc(N(C)C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H53N5O11/c1-21(40)36-26-24(41)17-34(30(45)46,11-13-39-14-15-48-20-33(39)10-12-38(19-33)31(47)50-32(2,3)4)49-28(26)27(43)25(42)18-35-29(44)22-8-7-9-23(16-22)37(5)6/h7-9,16,24-28,41-43H,10-15,17-20H2,1-6H3,(H,35,44)(H,36,40)(H,45,46) OWWXYXBEJMGXFZ-UHFFFAOYSA-N 778325 US20250313574, Example A-183 Myeloid cell surface antigen CD33 173 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778325 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778325&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893433 523296672 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560743 CC(=O)Nc1ccc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)cc1 InChI=1S/C34H51N5O12/c1-20(40)36-23-8-6-22(7-9-23)29(45)35-17-25(43)27(44)28-26(37-21(2)41)24(42)16-34(50-28,30(46)47)11-13-39-14-15-49-19-33(39)10-12-38(18-33)31(48)51-32(3,4)5/h6-9,24-28,42-44H,10-19H2,1-5H3,(H,35,45)(H,36,40)(H,37,41)(H,46,47) FODTUZFZHYOEAL-UHFFFAOYSA-N 778326 US20250313574, Example A-184 Myeloid cell surface antigen CD33 1090 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778326 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778326&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893434 523296673 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560744 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(F)c(F)c(F)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H45F3N4O11/c1-17(40)37-24-21(41)13-32(28(45)46,6-8-39-9-10-48-16-31(39)5-7-38(15-31)29(47)50-30(2,3)4)49-26(24)25(43)22(42)14-36-27(44)18-11-19(33)23(35)20(34)12-18/h11-12,21-22,24-26,41-43H,5-10,13-16H2,1-4H3,(H,36,44)(H,37,40)(H,45,46) MSYVKZHGZCTGGI-UHFFFAOYSA-N 778327 US20250313574, Example A-185 Myeloid cell surface antigen CD33 3600 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778327 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778327&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893435 523296674 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560745 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(Cl)c(Cl)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H46Cl2N4O11/c1-18(39)36-24-22(40)14-32(28(44)45,48-26(24)25(42)23(41)15-35-27(43)19-5-6-20(33)21(34)13-19)8-10-38-11-12-47-17-31(38)7-9-37(16-31)29(46)49-30(2,3)4/h5-6,13,22-26,40-42H,7-12,14-17H2,1-4H3,(H,35,43)(H,36,39)(H,44,45) KKKQWFIBDYAOLP-UHFFFAOYSA-N 778328 US20250313574, Example A-186 Myeloid cell surface antigen CD33 127 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778328 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778328&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893436 523296675 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560746 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccccc2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H48N4O11/c1-20(37)34-24-22(38)16-32(28(42)43,46-26(24)25(40)23(39)17-33-27(41)21-8-6-5-7-9-21)11-13-36-14-15-45-19-31(36)10-12-35(18-31)29(44)47-30(2,3)4/h5-9,22-26,38-40H,10-19H2,1-4H3,(H,33,41)(H,34,37)(H,42,43) WTQYMMFXKMNKCH-UHFFFAOYSA-N 778329 US20250313574, Example A-187 Myeloid cell surface antigen CD33 1010 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778329 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778329&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893437 523296676 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560747 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)on2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C30H47N5O12/c1-17-12-19(33-47-17)25(40)31-14-21(38)23(39)24-22(32-18(2)36)20(37)13-30(45-24,26(41)42)7-9-35-10-11-44-16-29(35)6-8-34(15-29)27(43)46-28(3,4)5/h12,20-24,37-39H,6-11,13-16H2,1-5H3,(H,31,40)(H,32,36)(H,41,42) XGAONVTZDYBTOT-UHFFFAOYSA-N 778330 US20250313574, Example A-188 Myeloid cell surface antigen CD33 2080 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778330&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893438 523296677 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560748 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cnc(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C32H49N5O12/c1-18-12-20(14-33-26(18)42)27(43)34-15-22(40)24(41)25-23(35-19(2)38)21(39)13-32(48-25,28(44)45)7-9-37-10-11-47-17-31(37)6-8-36(16-31)29(46)49-30(3,4)5/h12,14,21-25,39-41H,6-11,13,15-17H2,1-5H3,(H,33,42)(H,34,43)(H,35,38)(H,44,45) XFQKDJNCMJJFRD-UHFFFAOYSA-N 778331 US20250313574, Example A-189 Myeloid cell surface antigen CD33 150 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778331 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778331&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893439 523296678 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560749 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)cc(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O11/c1-20-13-21(2)15-23(14-20)29(43)35-17-25(41)27(42)28-26(36-22(3)39)24(40)16-34(48-28,30(44)45)8-10-38-11-12-47-19-33(38)7-9-37(18-33)31(46)49-32(4,5)6/h13-15,24-28,40-42H,7-12,16-19H2,1-6H3,(H,35,43)(H,36,39)(H,44,45) HIDDPQXBLZTFLA-UHFFFAOYSA-N 778332 US20250313574, Example A-190 Myeloid cell surface antigen CD33 119 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778332 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778332&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893440 523296679 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560750 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(=O)n(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C33H51N5O12/c1-19-13-21(16-36(6)28(19)44)27(43)34-15-23(41)25(42)26-24(35-20(2)39)22(40)14-33(49-26,29(45)46)8-10-38-11-12-48-18-32(38)7-9-37(17-32)30(47)50-31(3,4)5/h13,16,22-26,40-42H,7-12,14-15,17-18H2,1-6H3,(H,34,43)(H,35,39)(H,45,46) ADYLZEPXTLKSLP-UHFFFAOYSA-N 778333 US20250313574, Example A-191 Myeloid cell surface antigen CD33 163 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778333 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778333&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893441 523296680 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560751 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(F)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H51FN4O11/c1-19-13-22(14-20(2)25(19)35)29(44)36-16-24(42)27(43)28-26(37-21(3)40)23(41)15-34(49-28,30(45)46)8-10-39-11-12-48-18-33(39)7-9-38(17-33)31(47)50-32(4,5)6/h13-14,23-24,26-28,41-43H,7-12,15-18H2,1-6H3,(H,36,44)(H,37,40)(H,45,46) PDIHODPDXKEOES-UHFFFAOYSA-N 778334 US20250313574, Example A-192 Myeloid cell surface antigen CD33 47.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778334 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778334&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893442 523296681 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560752 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CN2CCCC3(CCN(C(=O)OC(C)(C)C)C3)C2)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O11/c1-19-12-22(13-20(2)26(19)42)29(44)35-15-24(41)27(43)28-25(36-21(3)39)23(40)14-34(48-28,30(45)46)18-37-10-7-8-33(16-37)9-11-38(17-33)31(47)49-32(4,5)6/h12-13,23-25,27-28,40-43H,7-11,14-18H2,1-6H3,(H,35,44)(H,36,39)(H,45,46) HCOZAHYBFRODFL-UHFFFAOYSA-N 778335 US20250313574, Example A-193 Myeloid cell surface antigen CD33 90.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778335 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778335&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893443 523296682 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560753 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/C2CCN(C(=O)OC(C)(C)C)C2)(C(=O)O)C[C@@H]1O InChI=1S/C32H47N3O11/c1-17-12-21(13-18(2)25(17)39)28(41)33-15-23(38)26(40)27-24(34-19(3)36)22(37)14-32(45-27,29(42)43)10-7-8-20-9-11-35(16-20)30(44)46-31(4,5)6/h7-8,12-13,20,22-24,26-27,37-40H,9-11,14-16H2,1-6H3,(H,33,41)(H,34,36)(H,42,43) UENHSBKPGQGFKC-UHFFFAOYSA-N 778336 US20250313574, Example A-194 Myeloid cell surface antigen CD33 26.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778336 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778336&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893444 523296683 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560754 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/C2(C)CCN(C(=O)OC(C)(C)C)C2)(C(=O)O)C[C@@H]1O InChI=1S/C33H49N3O11/c1-18-13-21(14-19(2)25(18)40)28(42)34-16-23(39)26(41)27-24(35-20(3)37)22(38)15-33(46-27,29(43)44)10-8-9-32(7)11-12-36(17-32)30(45)47-31(4,5)6/h8-9,13-14,22-24,26-27,38-41H,10-12,15-17H2,1-7H3,(H,34,42)(H,35,37)(H,43,44) QDTJINQFPGEOSC-UHFFFAOYSA-N 778337 US20250313574, Example A-195 Myeloid cell surface antigen CD33 42.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778337 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778337&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893445 523296684 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560755 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCCC2(C)CCN(C(=O)OC(C)(C)C)C2)(C(=O)O)C[C@@H]1O InChI=1S/C33H51N3O11/c1-18-13-21(14-19(2)25(18)40)28(42)34-16-23(39)26(41)27-24(35-20(3)37)22(38)15-33(46-27,29(43)44)10-8-9-32(7)11-12-36(17-32)30(45)47-31(4,5)6/h13-14,22-24,26-27,38-41H,8-12,15-17H2,1-7H3,(H,34,42)(H,35,37)(H,43,44) IFUMUCZBUWBSCH-UHFFFAOYSA-N 778338 US20250313574, Example A-196 Myeloid cell surface antigen CD33 257 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778338 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778338&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893446 523296685 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560756 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/C2(O)CCN(C(=O)OC(C)(C)C)C2)(C(=O)O)C[C@@H]1O InChI=1S/C32H47N3O12/c1-17-12-20(13-18(2)24(17)39)27(41)33-15-22(38)25(40)26-23(34-19(3)36)21(37)14-32(46-26,28(42)43)9-7-8-31(45)10-11-35(16-31)29(44)47-30(4,5)6/h7-8,12-13,21-23,25-26,37-40,45H,9-11,14-16H2,1-6H3,(H,33,41)(H,34,36)(H,42,43) MNCKDIHETYIHGR-UHFFFAOYSA-N 778339 US20250313574, Example A-197 Myeloid cell surface antigen CD33 181 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778339 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778339&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893447 523296686 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560757 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/C2(F)CCN(C(=O)OC(C)(C)C)C2)(C(=O)O)C[C@@H]1O InChI=1S/C32H46FN3O11/c1-17-12-20(13-18(2)24(17)40)27(42)34-15-22(39)25(41)26-23(35-19(3)37)21(38)14-32(46-26,28(43)44)9-7-8-31(33)10-11-36(16-31)29(45)47-30(4,5)6/h7-8,12-13,21-23,25-26,38-41H,9-11,14-16H2,1-6H3,(H,34,42)(H,35,37)(H,43,44) MEQPYCSPMVOTKB-UHFFFAOYSA-N 778340 US20250313574, Example A-198 Myeloid cell surface antigen CD33 148 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778340 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778340&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893448 523296687 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560758 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/C2CCN(c3cc(N(C)C)ccn3)C2)(C(=O)O)C[C@@H]1O InChI=1S/C34H47N5O9/c1-19-13-23(14-20(2)29(19)43)32(45)36-17-26(42)30(44)31-28(37-21(3)40)25(41)16-34(48-31,33(46)47)10-6-7-22-9-12-39(18-22)27-15-24(38(4)5)8-11-35-27/h6-8,11,13-15,22,25-26,28,30-31,41-44H,9-10,12,16-18H2,1-5H3,(H,36,45)(H,37,40)(H,46,47) ZLIKCBSCAYSLCE-UHFFFAOYSA-N 778341 US20250313574, Example A-199 Myeloid cell surface antigen CD33 9860 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778341 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778341&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893449 523296688 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560759 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@]1(C)O InChI=1S/C35H54N4O12/c1-20-14-23(15-21(2)25(20)42)29(44)36-16-24(41)26(43)27-28(37-22(3)40)33(7,48)17-35(50-27,30(45)46)9-11-39-12-13-49-19-34(39)8-10-38(18-34)31(47)51-32(4,5)6/h14-15,24,26-28,41-43,48H,8-13,16-19H2,1-7H3,(H,36,44)(H,37,40)(H,45,46) BITGUHXTORYUBV-UHFFFAOYSA-N 778342 US20250313574, Example A-200 Myeloid cell surface antigen CD33 131 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778342 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778342&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893450 523296689 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560760 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@]1(C)O InChI=1S/C35H54N4O12/c1-20-14-23(15-21(2)25(20)42)29(44)36-16-24(41)26(43)27-28(37-22(3)40)33(7,48)17-35(50-27,30(45)46)9-11-39-12-13-49-19-34(39)8-10-38(18-34)31(47)51-32(4,5)6/h14-15,24,26-28,41-43,48H,8-13,16-19H2,1-7H3,(H,36,44)(H,37,40)(H,45,46) BITGUHXTORYUBV-UHFFFAOYSA-N 778343 US20250313574, Example A-201 Myeloid cell surface antigen CD33 1720 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778343 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778343&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893451 523296690 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560761 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@H]2C[C@@H](O)C[C@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)O2)cc(C)c1O InChI=1S/C32H49N3O11/c1-19-12-21(13-20(2)25(19)38)27(40)33-16-23(37)26(39)24-14-22(36)15-32(45-24,28(41)42)7-9-35-10-11-44-18-31(35)6-8-34(17-31)29(43)46-30(3,4)5/h12-13,22-24,26,36-39H,6-11,14-18H2,1-5H3,(H,33,40)(H,41,42) HFMHGXXOHIVTNF-UHFFFAOYSA-N 778344 US20250313574, Example A-202 Myeloid cell surface antigen CD33 311 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778344 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778344&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292815 523296691 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560762 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)C[C@H](O)[C@H]2N(C)C)cc(C)c1O InChI=1S/C34H54N4O11/c1-20-14-22(15-21(2)26(20)41)29(43)35-17-24(40)27(42)28-25(36(6)7)23(39)16-34(48-28,30(44)45)9-11-38-12-13-47-19-33(38)8-10-37(18-33)31(46)49-32(3,4)5/h14-15,23-25,27-28,39-42H,8-13,16-19H2,1-7H3,(H,35,43)(H,44,45) NQIOITBWCSRBDG-UHFFFAOYSA-N 778345 US20250313574, Example A-203 Myeloid cell surface antigen CD33 >5000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778345 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778345&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292847 523296692 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560763 CC(=O)N[C@H]1[C@H]([C@H](O)[C@](C)(O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O12/c1-20-14-23(15-21(2)26(20)42)29(44)36-17-33(7,48)28(43)27-25(37-22(3)40)24(41)16-35(50-27,30(45)46)9-11-39-12-13-49-19-34(39)8-10-38(18-34)31(47)51-32(4,5)6/h14-15,24-25,27-28,41-43,48H,8-13,16-19H2,1-7H3,(H,36,44)(H,37,40)(H,45,46) RAOJHAOBKOVKEC-UHFFFAOYSA-N 778346 US20250313574, Example A-204 Myeloid cell surface antigen CD33 582 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778346 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778346&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893452 523296693 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560764 CC(=O)N[C@H]1[C@H]([C@H](O)[C@@](C)(O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C35H54N4O12/c1-20-14-23(15-21(2)26(20)42)29(44)36-17-33(7,48)28(43)27-25(37-22(3)40)24(41)16-35(50-27,30(45)46)9-11-39-12-13-49-19-34(39)8-10-38(18-34)31(47)51-32(4,5)6/h14-15,24-25,27-28,41-43,48H,8-13,16-19H2,1-7H3,(H,36,44)(H,37,40)(H,45,46) RAOJHAOBKOVKEC-UHFFFAOYSA-N 778347 US20250313574, Example A-205 Myeloid cell surface antigen CD33 1820 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778347 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778347&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893453 523296694 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560765 COC(=O)[C@@]1(CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)CCC[C@H](C[C@H](O)CNC(=O)c2cc(C)c3[nH]ccc3c2)O1 InChI=1S/C34H50N4O8/c1-23-17-25(18-24-8-12-35-28(23)24)29(40)36-20-26(39)19-27-7-6-9-34(45-27,30(41)43-5)11-14-38-15-16-44-22-33(38)10-13-37(21-33)31(42)46-32(2,3)4/h8,12,17-18,26-27,35,39H,6-7,9-11,13-16,19-22H2,1-5H3,(H,36,40) FNXWWDDJZAMLQN-UHFFFAOYSA-N 778348 US20250313574, Example A-206 Myeloid cell surface antigen CD33 >100000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778348 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778348&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 176889524 523296695 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560766 COC(=O)[C@@]1(CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)CCC[C@H](C[C@H](O)CNC(=O)c2cc(C)c3[nH]ccc3c2)O1 InChI=1S/C34H50N4O8/c1-23-17-25(18-24-8-12-35-28(23)24)29(40)36-20-26(39)19-27-7-6-9-34(45-27,30(41)43-5)11-14-38-15-16-44-22-33(38)10-13-37(21-33)31(42)46-32(2,3)4/h8,12,17-18,26-27,35,39H,6-7,9-11,13-16,19-22H2,1-5H3,(H,36,40) FNXWWDDJZAMLQN-UHFFFAOYSA-N 778349 US20250313574, Example A-207 Myeloid cell surface antigen CD33 3750 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778349 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778349&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 176889524 523296696 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560767 Cc1cc(C(=O)NC[C@@H](O)C[C@H]2CCC[C@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)O2)cc(C)c1O InChI=1S/C32H49N3O9/c1-21-15-23(16-22(2)26(21)37)27(38)33-18-24(36)17-25-7-6-8-32(43-25,28(39)40)10-12-35-13-14-42-20-31(35)9-11-34(19-31)29(41)44-30(3,4)5/h15-16,24-25,36-37H,6-14,17-20H2,1-5H3,(H,33,38)(H,39,40) QZZWFVGMXZGUJX-UHFFFAOYSA-N 778350 US20250313574, Example A-208 Myeloid cell surface antigen CD33 >20000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778350 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778350&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292748 523296697 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560768 Cc1cc(C(=O)NCC(O)C[C@@H]2O[C@@](C/C=C/C3CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)CCC2C)cc(C)c1O InChI=1S/C31H46N2O8/c1-19-9-12-31(28(37)38,11-7-8-22-10-13-33(18-22)29(39)41-30(4,5)6)40-25(19)16-24(34)17-32-27(36)23-14-20(2)26(35)21(3)15-23/h7-8,14-15,19,22,24-25,34-35H,9-13,16-18H2,1-6H3,(H,32,36)(H,37,38) BDMDLOAYZWXVGK-UHFFFAOYSA-N 778351 US20250313574, Example A-209 Myeloid cell surface antigen CD33 44500 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778351&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292783 523296698 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560769 Cc1cc(C(=O)NCC(O)C[C@@H]2O[C@@](C/C=C/C3CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)CCC2C)cc(C)c1O InChI=1S/C31H46N2O8/c1-19-9-12-31(28(37)38,11-7-8-22-10-13-33(18-22)29(39)41-30(4,5)6)40-25(19)16-24(34)17-32-27(36)23-14-20(2)26(35)21(3)15-23/h7-8,14-15,19,22,24-25,34-35H,9-13,16-18H2,1-6H3,(H,32,36)(H,37,38) BDMDLOAYZWXVGK-UHFFFAOYSA-N 778352 US20250313574, Example A-210 Myeloid cell surface antigen CD33 21400 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778352 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778352&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292783 523296699 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560770 Cc1cc(C(=O)NCC(O)C[C@@H]2O[C@@](C/C=C/C3CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)CCC2C)cc2cc[nH]c12 InChI=1S/C32H45N3O7/c1-20-8-12-32(29(38)39,11-6-7-22-10-14-35(19-22)30(40)42-31(3,4)5)41-26(20)17-25(36)18-34-28(37)24-15-21(2)27-23(16-24)9-13-33-27/h6-7,9,13,15-16,20,22,25-26,33,36H,8,10-12,14,17-19H2,1-5H3,(H,34,37)(H,38,39) FJBBIPIHIOHJJE-UHFFFAOYSA-N 778353 US20250313574, Example A-211 Myeloid cell surface antigen CD33 15200 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778353 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778353&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292747 523296700 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560771 Cc1cc(C(=O)NCC(O)C[C@@H]2O[C@@](C/C=C/C3CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)CCC2C)cc2cc[nH]c12 InChI=1S/C32H45N3O7/c1-20-8-12-32(29(38)39,11-6-7-22-10-14-35(19-22)30(40)42-31(3,4)5)41-26(20)17-25(36)18-34-28(37)24-15-21(2)27-23(16-24)9-13-33-27/h6-7,9,13,15-16,20,22,25-26,33,36H,8,10-12,14,17-19H2,1-5H3,(H,34,37)(H,38,39) FJBBIPIHIOHJJE-UHFFFAOYSA-N 778354 US20250313574, Example A-212 Myeloid cell surface antigen CD33 17400 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778354 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778354&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292747 523296701 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560772 Cc1cc(C(=O)NCC(O)C[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)CCC2C)cc(C)c1O InChI=1S/C33H51N3O9/c1-21-7-8-33(29(40)41,44-26(21)17-25(37)18-34-28(39)24-15-22(2)27(38)23(3)16-24)10-12-36-13-14-43-20-32(36)9-11-35(19-32)30(42)45-31(4,5)6/h15-16,21,25-26,37-38H,7-14,17-20H2,1-6H3,(H,34,39)(H,40,41) GFSFEVISFXVGNK-UHFFFAOYSA-N 778355 US20250313574, Example A-213 Myeloid cell surface antigen CD33 17900 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778355&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292832 523296702 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560773 Cc1cc(C(=O)NCC(O)C[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)CCC2C)cc(C)c1O InChI=1S/C33H51N3O9/c1-21-7-8-33(29(40)41,44-26(21)17-25(37)18-34-28(39)24-15-22(2)27(38)23(3)16-24)10-12-36-13-14-43-20-32(36)9-11-35(19-32)30(42)45-31(4,5)6/h15-16,21,25-26,37-38H,7-14,17-20H2,1-6H3,(H,34,39)(H,40,41) GFSFEVISFXVGNK-UHFFFAOYSA-N 778356 US20250313574, Example A-214 Myeloid cell surface antigen CD33 9800 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778356 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778356&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292832 523296703 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560774 Cc1cc(C(=O)NCC(O)C[C@@H]2O[C@@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)CCC2C)cc(C)c1O InChI=1S/C33H51N3O9/c1-21-7-8-33(29(40)41,44-26(21)17-25(37)18-34-28(39)24-15-22(2)27(38)23(3)16-24)10-12-36-13-14-43-20-32(36)9-11-35(19-32)30(42)45-31(4,5)6/h15-16,21,25-26,37-38H,7-14,17-20H2,1-6H3,(H,34,39)(H,40,41) GFSFEVISFXVGNK-UHFFFAOYSA-N 778357 US20250313574, Example A-215 Myeloid cell surface antigen CD33 60400 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778357 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778357&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292832 523296704 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560775 Cc1cc(C(=O)NC[C@@H](O)C[C@H]2CC[C@H](C)[C@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)O2)cc2cc[nH]c12 InChI=1S/C34H50N4O8/c1-22-16-25(17-24-8-11-35-28(22)24)29(40)36-19-26(39)18-27-7-6-23(2)34(45-27,30(41)42)10-13-38-14-15-44-21-33(38)9-12-37(20-33)31(43)46-32(3,4)5/h8,11,16-17,23,26-27,35,39H,6-7,9-10,12-15,18-21H2,1-5H3,(H,36,40)(H,41,42) IVYJTSSNOZTROP-UHFFFAOYSA-N 778358 US20250313574, Example A-216 Myeloid cell surface antigen CD33 12200 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778358 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778358&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 170444406 523296705 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560776 Cc1cc(C(=O)NC[C@@H](O)C[C@H]2CC[C@@H](C)[C@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)O2)cc2cc[nH]c12 InChI=1S/C34H50N4O8/c1-22-16-25(17-24-8-11-35-28(22)24)29(40)36-19-26(39)18-27-7-6-23(2)34(45-27,30(41)42)10-13-38-14-15-44-21-33(38)9-12-37(20-33)31(43)46-32(3,4)5/h8,11,16-17,23,26-27,35,39H,6-7,9-10,12-15,18-21H2,1-5H3,(H,36,40)(H,41,42) IVYJTSSNOZTROP-UHFFFAOYSA-N 778359 US20250313574, Example A-217 Myeloid cell surface antigen CD33 >20000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778359 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778359&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 170444374 523296706 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560777 Cc1cc(C(=O)NC[C@H](O)C[C@H]2CC[C@H](C)[C@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)O2)cc2cc[nH]c12 InChI=1S/C34H50N4O8/c1-22-16-25(17-24-8-11-35-28(22)24)29(40)36-19-26(39)18-27-7-6-23(2)34(45-27,30(41)42)10-13-38-14-15-44-21-33(38)9-12-37(20-33)31(43)46-32(3,4)5/h8,11,16-17,23,26-27,35,39H,6-7,9-10,12-15,18-21H2,1-5H3,(H,36,40)(H,41,42) IVYJTSSNOZTROP-UHFFFAOYSA-N 778360 US20250313574, Example A-218 Myeloid cell surface antigen CD33 >20000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778360 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778360&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292781 523296707 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560778 Cc1cc(C(=O)NC[C@H](O)C[C@H]2CC[C@@H](C)[C@](CCN3CCOC[C@@]34CCN(C(=O)OC(C)(C)C)C4)(C(=O)O)O2)cc2cc[nH]c12 InChI=1S/C34H50N4O8/c1-22-16-25(17-24-8-11-35-28(22)24)29(40)36-19-26(39)18-27-7-6-23(2)34(45-27,30(41)42)10-13-38-14-15-44-21-33(38)9-12-37(20-33)31(43)46-32(3,4)5/h8,11,16-17,23,26-27,35,39H,6-7,9-10,12-15,18-21H2,1-5H3,(H,36,40)(H,41,42) IVYJTSSNOZTROP-UHFFFAOYSA-N 778361 US20250313574, Example A-219 Myeloid cell surface antigen CD33 >20000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778361 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778361&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292740 523296708 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560779 CC(=O)NC1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC(=O)N2CCOC[C@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N4O13/c1-18-11-21(12-19(2)26(18)43)29(45)35-15-23(41)27(44)28-25(36-20(3)39)22(40)13-34(50-28,30(46)47)14-24(42)38-9-10-49-17-33(38)7-8-37(16-33)31(48)51-32(4,5)6/h11-12,22-23,25,27-28,40-41,43-44H,7-10,13-17H2,1-6H3,(H,35,45)(H,36,39)(H,46,47) ASZOJVCQSRQWOP-UHFFFAOYSA-N 778362 US20250313574, Example A-220 Myeloid cell surface antigen CD33 55.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778362 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778362&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893454 523296709 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560780 CC(=O)NC1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC(=O)N2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N4O13/c1-18-11-21(12-19(2)26(18)43)29(45)35-15-23(41)27(44)28-25(36-20(3)39)22(40)13-34(50-28,30(46)47)14-24(42)38-9-10-49-17-33(38)7-8-37(16-33)31(48)51-32(4,5)6/h11-12,22-23,25,27-28,40-41,43-44H,7-10,13-17H2,1-6H3,(H,35,45)(H,36,39)(H,46,47) ASZOJVCQSRQWOP-UHFFFAOYSA-N 778363 US20250313574, Example A-221 Myeloid cell surface antigen CD33 162 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778363 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778363&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893455 523296710 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560781 CC(=O)NC1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC(=O)N2CCOC[C@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H50N4O13/c1-18-11-21(12-19(2)26(18)43)29(45)35-15-23(41)27(44)28-25(36-20(3)39)22(40)13-34(50-28,30(46)47)14-24(42)38-9-10-49-17-33(38)7-8-37(16-33)31(48)51-32(4,5)6/h11-12,22-23,25,27-28,40-41,43-44H,7-10,13-17H2,1-6H3,(H,35,45)(H,36,39)(H,46,47) ASZOJVCQSRQWOP-UHFFFAOYSA-N 778364 US20250313574, Example A-222 Myeloid cell surface antigen CD33 55.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778364&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893454 523296711 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560782 CC(=O)NC1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC(=O)N2CCOC[C@@]23CCN(C(=O)NC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C34H51N5O12/c1-18-11-21(12-19(2)26(18)44)29(46)35-15-23(42)27(45)28-25(36-20(3)40)22(41)13-34(51-28,30(47)48)14-24(43)39-9-10-50-17-33(39)7-8-38(16-33)31(49)37-32(4,5)6/h11-12,22-23,25,27-28,41-42,44-45H,7-10,13-17H2,1-6H3,(H,35,46)(H,36,40)(H,37,49)(H,47,48) YTDMGSMPFLICAS-UHFFFAOYSA-N 778365 US20250313574, Example A-223 Myeloid cell surface antigen CD33 123 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778365 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778365&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893456 523296712 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560783 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C[C@H]2COC[C@]3(CCN(C(=O)OC(C)(C)C)C3)N2)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O12/c1-17-9-20(10-18(2)25(17)41)28(43)34-13-23(40)26(42)27-24(35-19(3)38)22(39)12-33(48-27,29(44)45)11-21-14-47-16-32(36-21)7-8-37(15-32)30(46)49-31(4,5)6/h9-10,21-24,26-27,36,39-42H,7-8,11-16H2,1-6H3,(H,34,43)(H,35,38)(H,44,45) JHAVGPYGLGWHRT-UHFFFAOYSA-N 778366 US20250313574, Example A-224 Myeloid cell surface antigen CD33 143 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778366 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778366&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893457 523296713 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560784 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C[C@@H]2COC[C@]3(CCN(C(=O)OC(C)(C)C)C3)N2)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O12/c1-17-9-20(10-18(2)25(17)41)28(43)34-13-23(40)26(42)27-24(35-19(3)38)22(39)12-33(48-27,29(44)45)11-21-14-47-16-32(36-21)7-8-37(15-32)30(46)49-31(4,5)6/h9-10,21-24,26-27,36,39-42H,7-8,11-16H2,1-6H3,(H,34,43)(H,35,38)(H,44,45) JHAVGPYGLGWHRT-UHFFFAOYSA-N 778367 US20250313574, Example A-225 Myeloid cell surface antigen CD33 552 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778367 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778367&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893458 523296714 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560785 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C[C@@H]2COC[C@@]3(CCN(C(=O)OC(C)(C)C)C3)N2)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O12/c1-17-9-20(10-18(2)25(17)41)28(43)34-13-23(40)26(42)27-24(35-19(3)38)22(39)12-33(48-27,29(44)45)11-21-14-47-16-32(36-21)7-8-37(15-32)30(46)49-31(4,5)6/h9-10,21-24,26-27,36,39-42H,7-8,11-16H2,1-6H3,(H,34,43)(H,35,38)(H,44,45) JHAVGPYGLGWHRT-UHFFFAOYSA-N 778368 US20250313574, Example A-226 Myeloid cell surface antigen CD33 3870 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778368 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778368&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 176889563 523296715 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560786 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C[C@H]2COC[C@@]3(CCN(C(=O)OC(C)(C)C)C3)N2)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O12/c1-17-9-20(10-18(2)25(17)41)28(43)34-13-23(40)26(42)27-24(35-19(3)38)22(39)12-33(48-27,29(44)45)11-21-14-47-16-32(36-21)7-8-37(15-32)30(46)49-31(4,5)6/h9-10,21-24,26-27,36,39-42H,7-8,11-16H2,1-6H3,(H,34,43)(H,35,38)(H,44,45) JHAVGPYGLGWHRT-UHFFFAOYSA-N 778369 US20250313574, Example A-227 Myeloid cell surface antigen CD33 12.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778369 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778369&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893459 523296716 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560787 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C[C@H]2COC[C@@]3(CCN(C(=O)NC(C)(C)C)C3)N2)(C(=O)O)C[C@@H]1O InChI=1S/C33H51N5O11/c1-17-9-20(10-18(2)25(17)42)28(44)34-13-23(41)26(43)27-24(35-19(3)39)22(40)12-33(49-27,29(45)46)11-21-14-48-16-32(36-21)7-8-38(15-32)30(47)37-31(4,5)6/h9-10,21-24,26-27,36,40-43H,7-8,11-16H2,1-6H3,(H,34,44)(H,35,39)(H,37,47)(H,45,46) ZJFMGVKAOKWYEB-UHFFFAOYSA-N 778370 US20250313574, Example A-228 Myeloid cell surface antigen CD33 14.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778370 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778370&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893460 523296717 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560788 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C[C@@H]2COC[C@]3(CCN(C(=O)OC(C)(C)C)C3)N2)(C(=O)O)C[C@@H]1O InChI=1S/C33H50N4O12/c1-17-9-20(10-18(2)25(17)41)28(43)34-13-23(40)26(42)27-24(35-19(3)38)22(39)12-33(48-27,29(44)45)11-21-14-47-16-32(36-21)7-8-37(15-32)30(46)49-31(4,5)6/h9-10,21-24,26-27,36,39-42H,7-8,11-16H2,1-6H3,(H,34,43)(H,35,38)(H,44,45) JHAVGPYGLGWHRT-UHFFFAOYSA-N 778371 US20250313574, Example A-229 Myeloid cell surface antigen CD33 22.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778371 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778371&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893458 523296718 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560789 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C[C@@H]2COCC3(CCN(C(=O)OC(C)(C)C)CC3)N2)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O12/c1-18-11-21(12-19(2)26(18)42)29(44)35-15-24(41)27(43)28-25(36-20(3)39)23(40)14-34(49-28,30(45)46)13-22-16-48-17-33(37-22)7-9-38(10-8-33)31(47)50-32(4,5)6/h11-12,22-25,27-28,37,40-43H,7-10,13-17H2,1-6H3,(H,35,44)(H,36,39)(H,45,46) QFVSVJMMDAVQMP-UHFFFAOYSA-N 778372 US20250313574, Example A-230 Myeloid cell surface antigen CD33 10620 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778372 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778372&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292755 523296719 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560790 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C[C@H]2COCC3(CCN(C(=O)OC(C)(C)C)CC3)N2)(C(=O)O)C[C@@H]1O InChI=1S/C34H52N4O12/c1-18-11-21(12-19(2)26(18)42)29(44)35-15-24(41)27(43)28-25(36-20(3)39)23(40)14-34(49-28,30(45)46)13-22-16-48-17-33(37-22)7-9-38(10-8-33)31(47)50-32(4,5)6/h11-12,22-25,27-28,37,40-43H,7-10,13-17H2,1-6H3,(H,35,44)(H,36,39)(H,45,46) QFVSVJMMDAVQMP-UHFFFAOYSA-N 778373 US20250313574, Example A-231 Myeloid cell surface antigen CD33 1410 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778373 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778373&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893461 523296720 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560791 COCc1cc2cc(C(=O)NCc3cccc(/C=C/C[C@]4(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c5cc(C)c(O)c(C)c5)O4)c3)ccc2[nH]1 InChI=1S/C41H48N4O11/c1-22-13-29(14-23(2)35(22)49)39(52)43-20-33(48)36(50)37-34(44-24(3)46)32(47)18-41(56-37,40(53)54)12-6-9-25-7-5-8-26(15-25)19-42-38(51)27-10-11-31-28(16-27)17-30(45-31)21-55-4/h5-11,13-17,32-34,36-37,45,47-50H,12,18-21H2,1-4H3,(H,42,51)(H,43,52)(H,44,46)(H,53,54) HAWFPRTZRBXENC-UHFFFAOYSA-N 778374 US20250313574, Example A-232 Myeloid cell surface antigen CD33 74.0 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778374 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778374&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893462 523296721 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560792 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2ccccc2CNC(=O)C2CCCOC2)(C(=O)O)C[C@@H]1O InChI=1S/C36H47N3O11/c1-20-14-26(15-21(2)30(20)43)34(46)38-18-28(42)31(44)32-29(39-22(3)40)27(41)16-36(50-32,35(47)48)12-6-10-23-8-4-5-9-24(23)17-37-33(45)25-11-7-13-49-19-25/h4-6,8-10,14-15,25,27-29,31-32,41-44H,7,11-13,16-19H2,1-3H3,(H,37,45)(H,38,46)(H,39,40)(H,47,48) CCTNBDOFEDRECR-UHFFFAOYSA-N 778375 US20250313574, Example A-233 Myeloid cell surface antigen CD33 8990 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778375 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778375&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893463 523296722 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560793 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]ccc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C39H44N4O10/c1-21-14-28(15-22(2)33(21)47)37(50)42-20-31(46)34(48)35-32(43-23(3)44)30(45)18-39(53-35,38(51)52)12-5-8-24-6-4-7-25(16-24)19-41-36(49)27-9-10-29-26(17-27)11-13-40-29/h4-11,13-17,30-32,34-35,40,45-48H,12,18-20H2,1-3H3,(H,41,49)(H,42,50)(H,43,44)(H,51,52) NKXQULOTHZWLBX-UHFFFAOYSA-N 778376 US20250313574, Example A-234 Myeloid cell surface antigen CD33 930 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778376 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778376&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292782 523296723 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560794 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4cn[nH]c4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C38H43N5O10/c1-20-12-27(13-21(2)32(20)47)36(50)40-19-30(46)33(48)34-31(42-22(3)44)29(45)16-38(53-34,37(51)52)11-5-8-23-6-4-7-24(14-23)17-39-35(49)25-9-10-26-18-41-43-28(26)15-25/h4-10,12-15,18,29-31,33-34,45-48H,11,16-17,19H2,1-3H3,(H,39,49)(H,40,50)(H,41,43)(H,42,44)(H,51,52) HMEWHDYVLPSZMY-UHFFFAOYSA-N 778377 US20250313574, Example A-235 Myeloid cell surface antigen CD33 2090 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778377 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778377&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893464 523296724 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560795 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]cnc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C38H43N5O10/c1-20-12-26(13-21(2)32(20)47)36(50)40-18-30(46)33(48)34-31(43-22(3)44)29(45)16-38(53-34,37(51)52)11-5-8-23-6-4-7-24(14-23)17-39-35(49)25-9-10-27-28(15-25)42-19-41-27/h4-10,12-15,19,29-31,33-34,45-48H,11,16-18H2,1-3H3,(H,39,49)(H,40,50)(H,41,42)(H,43,44)(H,51,52) QBRQTDXWCXDPOG-UHFFFAOYSA-N 778378 US20250313574, Example A-236 Myeloid cell surface antigen CD33 2010 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778378 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778378&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292728 523296725 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560796 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]nnc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C37H42N6O10/c1-19-12-25(13-20(2)31(19)47)35(50)39-18-29(46)32(48)33-30(40-21(3)44)28(45)16-37(53-33,36(51)52)11-5-8-22-6-4-7-23(14-22)17-38-34(49)24-9-10-26-27(15-24)42-43-41-26/h4-10,12-15,28-30,32-33,45-48H,11,16-18H2,1-3H3,(H,38,49)(H,39,50)(H,40,44)(H,51,52)(H,41,42,43) XDDULGQZJMOAQQ-UHFFFAOYSA-N 778379 US20250313574, Example A-237 Myeloid cell surface antigen CD33 5030 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778379 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778379&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292842 523296726 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560797 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]c(C)c(C)c4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H48N4O10/c1-21-14-29(15-22(2)35(21)49)39(52)43-20-33(48)36(50)37-34(45-25(5)46)32(47)18-41(55-37,40(53)54)13-7-10-26-8-6-9-27(16-26)19-42-38(51)28-11-12-31-30(17-28)23(3)24(4)44-31/h6-12,14-17,32-34,36-37,44,47-50H,13,18-20H2,1-5H3,(H,42,51)(H,43,52)(H,45,46)(H,53,54) PKDPZBGPPGJIFG-UHFFFAOYSA-N 778380 US20250313574, Example A-238 Myeloid cell surface antigen CD33 347 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778380 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778380&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292887 523296727 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560798 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc(NS(C)(=O)=O)cc3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C38H46N4O12S/c1-21-15-27(16-22(2)32(21)46)36(49)40-20-30(45)33(47)34-31(41-23(3)43)29(44)18-38(54-34,37(50)51)14-6-9-24-7-5-8-25(17-24)19-39-35(48)26-10-12-28(13-11-26)42-55(4,52)53/h5-13,15-17,29-31,33-34,42,44-47H,14,18-20H2,1-4H3,(H,39,48)(H,40,49)(H,41,43)(H,50,51) CLTVVBLVLMTVRX-UHFFFAOYSA-N 778381 US20250313574, Example A-239 Myeloid cell surface antigen CD33 1120 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778381 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778381&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292857 523296728 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560799 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc(Nc4ncccn4)cc3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H46N6O10/c1-23-17-29(18-24(2)34(23)51)38(54)45-22-32(50)35(52)36-33(46-25(3)48)31(49)20-41(57-36,39(55)56)14-5-9-26-7-4-8-27(19-26)21-44-37(53)28-10-12-30(13-11-28)47-40-42-15-6-16-43-40/h4-13,15-19,31-33,35-36,49-52H,14,20-22H2,1-3H3,(H,44,53)(H,45,54)(H,46,48)(H,55,56)(H,42,43,47) AWWLEKXISWOBRT-UHFFFAOYSA-N 778382 US20250313574, Example A-240 Myeloid cell surface antigen CD33 227 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778382 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778382&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292791 523296729 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560800 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3cccc(Nc4nccs4)c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C40H45N5O10S/c1-22-15-28(16-23(2)33(22)49)37(52)43-21-31(48)34(50)35-32(44-24(3)46)30(47)19-40(55-35,38(53)54)12-6-9-25-7-4-8-26(17-25)20-42-36(51)27-10-5-11-29(18-27)45-39-41-13-14-56-39/h4-11,13-18,30-32,34-35,47-50H,12,19-21H2,1-3H3,(H,41,45)(H,42,51)(H,43,52)(H,44,46)(H,53,54) MUFALAFMVXQYHM-UHFFFAOYSA-N 778383 US20250313574, Example A-241 Myeloid cell surface antigen CD33 7970 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778383 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778383&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292705 523296730 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560801 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]ccc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C39H44N4O10/c1-21-14-28(15-22(2)33(21)47)37(50)42-20-31(46)34(48)35-32(43-23(3)44)30(45)18-39(53-35,38(51)52)12-5-8-24-6-4-7-25(16-24)19-41-36(49)27-9-10-29-26(17-27)11-13-40-29/h4-11,13-17,30-32,34-35,40,45-48H,12,18-20H2,1-3H3,(H,41,49)(H,42,50)(H,43,44)(H,51,52) NKXQULOTHZWLBX-UHFFFAOYSA-N 778384 US20250313574, Example A-242 Myeloid cell surface antigen CD33 502 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778384 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778384&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292782 523296731 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560802 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]c(C(C)O)nc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C40H47N5O11/c1-20-13-27(14-21(2)33(20)50)38(53)42-19-31(49)34(51)35-32(43-23(4)47)30(48)17-40(56-35,39(54)55)12-6-9-24-7-5-8-25(15-24)18-41-37(52)26-10-11-28-29(16-26)45-36(44-28)22(3)46/h5-11,13-16,22,30-32,34-35,46,48-51H,12,17-19H2,1-4H3,(H,41,52)(H,42,53)(H,43,47)(H,44,45)(H,54,55) ZNDXTWNJXBBGDW-UHFFFAOYSA-N 778385 US20250313574, Example A-243 Myeloid cell surface antigen CD33 255 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778385 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778385&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292959 523296732 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560803 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)C3(C)COC3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C35H45N3O11/c1-19-11-24(12-20(2)28(19)42)31(44)36-16-26(41)29(43)30-27(38-21(3)39)25(40)14-35(49-30,33(46)47)10-6-9-22-7-5-8-23(13-22)15-37-32(45)34(4)17-48-18-34/h5-9,11-13,25-27,29-30,40-43H,10,14-18H2,1-4H3,(H,36,44)(H,37,45)(H,38,39)(H,46,47) FVKMFVVFNUNCLV-UHFFFAOYSA-N 778386 US20250313574, Example A-244 Myeloid cell surface antigen CD33 9560 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778386 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778386&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292849 523296733 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560804 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3cccc(NCc4nc(C)cs4)c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C42H49N5O10S/c1-23-14-30(15-24(2)36(23)51)40(54)45-20-33(50)37(52)38-35(47-26(4)48)32(49)18-42(57-38,41(55)56)13-7-10-27-8-5-9-28(16-27)19-44-39(53)29-11-6-12-31(17-29)43-21-34-46-25(3)22-58-34/h5-12,14-17,22,32-33,35,37-38,43,49-52H,13,18-21H2,1-4H3,(H,44,53)(H,45,54)(H,47,48)(H,55,56) RWRRSZVRCLDXPU-UHFFFAOYSA-N 778387 US20250313574, Example A-245 Myeloid cell surface antigen CD33 9460 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778387 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778387&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292894 523296734 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560805 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3cccc(NCc4cncs4)c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H47N5O10S/c1-23-13-29(14-24(2)35(23)50)39(53)45-21-33(49)36(51)37-34(46-25(3)47)32(48)17-41(56-37,40(54)55)12-6-9-26-7-4-8-27(15-26)18-44-38(52)28-10-5-11-30(16-28)43-20-31-19-42-22-57-31/h4-11,13-16,19,22,32-34,36-37,43,48-51H,12,17-18,20-21H2,1-3H3,(H,44,52)(H,45,53)(H,46,47)(H,54,55) PKFPCXLEDRUPIL-UHFFFAOYSA-N 778388 US20250313574, Example A-246 Myeloid cell surface antigen CD33 4000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778388 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778388&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292731 523296735 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560806 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)C3CCC(Nc4cnccn4)CC3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H52N6O10/c1-23-16-29(17-24(2)35(23)51)39(54)45-21-32(50)36(52)37-34(46-25(3)48)31(49)19-41(57-37,40(55)56)13-5-8-26-6-4-7-27(18-26)20-44-38(53)28-9-11-30(12-10-28)47-33-22-42-14-15-43-33/h4-8,14-18,22,28,30-32,34,36-37,49-52H,9-13,19-21H2,1-3H3,(H,43,47)(H,44,53)(H,45,54)(H,46,48)(H,55,56) XORCTTVQFOCLGS-UHFFFAOYSA-N 778389 US20250313574, Example A-247 Myeloid cell surface antigen CD33 353 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778389 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778389&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292765 523296736 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560807 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]c(CCO)cc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H48N4O11/c1-22-14-29(15-23(2)35(22)50)39(53)43-21-33(49)36(51)37-34(44-24(3)47)32(48)19-41(56-37,40(54)55)12-5-8-25-6-4-7-26(16-25)20-42-38(52)27-9-10-31-28(17-27)18-30(45-31)11-13-46/h4-10,14-18,32-34,36-37,45-46,48-51H,11-13,19-21H2,1-3H3,(H,42,52)(H,43,53)(H,44,47)(H,54,55) BLUABLAGJWWWQR-UHFFFAOYSA-N 778390 US20250313574, Example A-248 Myeloid cell surface antigen CD33 682 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778390 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778390&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292900 523296737 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560808 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]c(C(C)(C)CO)cc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C43H52N4O11/c1-23-14-30(15-24(2)36(23)52)40(55)45-21-33(51)37(53)38-35(46-25(3)49)32(50)19-43(58-38,41(56)57)13-7-10-26-8-6-9-27(16-26)20-44-39(54)28-11-12-31-29(17-28)18-34(47-31)42(4,5)22-48/h6-12,14-18,32-33,35,37-38,47-48,50-53H,13,19-22H2,1-5H3,(H,44,54)(H,45,55)(H,46,49)(H,56,57) ZTXWESXKHROWGS-UHFFFAOYSA-N 778391 US20250313574, Example A-249 Myeloid cell surface antigen CD33 224 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778391 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778391&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893465 523296738 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560809 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]c(-c5c[nH]c6ccccc56)cc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C47H49N5O10/c1-25-16-32(17-26(2)41(25)56)45(59)50-24-39(55)42(57)43-40(51-27(3)53)38(54)21-47(62-43,46(60)61)15-7-10-28-8-6-9-29(18-28)22-49-44(58)30-13-14-35-31(19-30)20-37(52-35)34-23-48-36-12-5-4-11-33(34)36/h4-14,16-20,23,38-40,42-43,48,52,54-57H,15,21-22,24H2,1-3H3,(H,49,58)(H,50,59)(H,51,53)(H,60,61) HXKBUIVWXAPTCH-UHFFFAOYSA-N 778392 US20250313574, Example A-250 Myeloid cell surface antigen CD33 3260 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778392 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778392&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893466 523296739 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560810 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3cccc(NC(C)(C)C)c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H52N4O10/c1-23-16-29(17-24(2)34(23)49)38(52)43-22-32(48)35(50)36-33(44-25(3)46)31(47)20-41(55-36,39(53)54)15-9-12-26-10-7-11-27(18-26)21-42-37(51)28-13-8-14-30(19-28)45-40(4,5)6/h7-14,16-19,31-33,35-36,45,47-50H,15,20-22H2,1-6H3,(H,42,51)(H,43,52)(H,44,46)(H,53,54) YQACRAOSDVZYFF-UHFFFAOYSA-N 778393 US20250313574, Example A-251 Myeloid cell surface antigen CD33 9790 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778393 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778393&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292944 523296740 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560811 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]c(-c5cccn5-c5ncccn5)nc4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C46H48N8O10/c1-25-18-31(19-26(2)38(25)58)43(61)50-24-36(57)39(59)40-37(51-27(3)55)35(56)22-46(64-40,44(62)63)14-5-10-28-8-4-9-29(20-28)23-49-42(60)30-12-13-32-33(21-30)53-41(52-32)34-11-6-17-54(34)45-47-15-7-16-48-45/h4-13,15-21,35-37,39-40,56-59H,14,22-24H2,1-3H3,(H,49,60)(H,50,61)(H,51,55)(H,52,53)(H,62,63) KKNCNUWJQQMJOJ-UHFFFAOYSA-N 778394 US20250313574, Example A-252 Myeloid cell surface antigen CD33 578 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778394 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778394&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292810 523296741 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560812 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)C3CCC(Nc4ncccn4)CC3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H52N6O10/c1-23-17-29(18-24(2)34(23)51)38(54)45-22-32(50)35(52)36-33(46-25(3)48)31(49)20-41(57-36,39(55)56)14-5-9-26-7-4-8-27(19-26)21-44-37(53)28-10-12-30(13-11-28)47-40-42-15-6-16-43-40/h4-9,15-19,28,30-33,35-36,49-52H,10-14,20-22H2,1-3H3,(H,44,53)(H,45,54)(H,46,48)(H,55,56)(H,42,43,47) MOXFGMYMVBRALJ-UHFFFAOYSA-N 778395 US20250313574, Example A-253 Myeloid cell surface antigen CD33 195 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778395 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778395&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292892 523296742 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560813 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc4[nH]c5c(c4c3)CCC(=O)N5C)c2)(C(=O)O)C[C@@H]1O InChI=1S/C43H49N5O11/c1-22-15-28(16-23(2)36(22)53)41(56)45-21-33(51)37(54)38-35(46-24(3)49)32(50)19-43(59-38,42(57)58)14-6-9-25-7-5-8-26(17-25)20-44-40(55)27-10-12-31-30(18-27)29-11-13-34(52)48(4)39(29)47-31/h5-10,12,15-18,32-33,35,37-38,47,50-51,53-54H,11,13-14,19-21H2,1-4H3,(H,44,55)(H,45,56)(H,46,49)(H,57,58) ALZQGTZGDPUYTP-UHFFFAOYSA-N 778396 US20250313574, Example A-254 Myeloid cell surface antigen CD33 193 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778396 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778396&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292710 523296743 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560814 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)C3CCC(Nc4ncccn4)C3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C40H50N6O10/c1-22-15-28(16-23(2)33(22)50)37(53)44-21-31(49)34(51)35-32(45-24(3)47)30(48)19-40(56-35,38(54)55)12-5-9-25-7-4-8-26(17-25)20-43-36(52)27-10-11-29(18-27)46-39-41-13-6-14-42-39/h4-9,13-17,27,29-32,34-35,48-51H,10-12,18-21H2,1-3H3,(H,43,52)(H,44,53)(H,45,47)(H,54,55)(H,41,42,46) OMGQKPGTGAOOFK-UHFFFAOYSA-N 778397 US20250313574, Example A-255 Myeloid cell surface antigen CD33 4460 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778397 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778397&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292760 523296744 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560815 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)C3CCC[C@H](Nc4ncccn4)C3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H52N6O10/c1-23-16-29(17-24(2)34(23)51)38(54)45-22-32(50)35(52)36-33(46-25(3)48)31(49)20-41(57-36,39(55)56)13-6-10-26-8-4-9-27(18-26)21-44-37(53)28-11-5-12-30(19-28)47-40-42-14-7-15-43-40/h4,6-10,14-18,28,30-33,35-36,49-52H,5,11-13,19-22H2,1-3H3,(H,44,53)(H,45,54)(H,46,48)(H,55,56)(H,42,43,47) DYAZEKMCUUIGGB-UHFFFAOYSA-N 778398 US20250313574, Example A-256 Myeloid cell surface antigen CD33 2170 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778398 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778398&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893467 523296745 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560816 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)c3ccc(NC(C)(C)C)cc3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H52N4O10/c1-23-17-29(18-24(2)34(23)49)38(52)43-22-32(48)35(50)36-33(44-25(3)46)31(47)20-41(55-36,39(53)54)16-8-11-26-9-7-10-27(19-26)21-42-37(51)28-12-14-30(15-13-28)45-40(4,5)6/h7-15,17-19,31-33,35-36,45,47-50H,16,20-22H2,1-6H3,(H,42,51)(H,43,52)(H,44,46)(H,53,54) OCFWRDRKTVCZAY-UHFFFAOYSA-N 778399 US20250313574, Example A-257 Myeloid cell surface antigen CD33 1600 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778399 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778399&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292732 523296746 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560817 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)C3CCC(Nc4ccc(C(N)=O)cn4)CC3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C43H54N6O11/c1-23-16-30(17-24(2)36(23)53)41(57)47-22-33(52)37(54)38-35(48-25(3)50)32(51)19-43(60-38,42(58)59)15-5-8-26-6-4-7-27(18-26)20-46-40(56)28-9-12-31(13-10-28)49-34-14-11-29(21-45-34)39(44)55/h4-8,11,14,16-18,21,28,31-33,35,37-38,51-54H,9-10,12-13,15,19-20,22H2,1-3H3,(H2,44,55)(H,45,49)(H,46,56)(H,47,57)(H,48,50)(H,58,59) LHQJBUHDTFSMKA-UHFFFAOYSA-N 778400 US20250313574, Example A-258 Myeloid cell surface antigen CD33 9370 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778400 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778400&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292750 523296747 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560818 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)C3CCCC(Nc4ccc(C)cn4)C3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C43H55N5O10/c1-24-13-14-35(44-21-24)48-32-12-6-11-30(19-32)40(54)45-22-29-9-5-8-28(18-29)10-7-15-43(42(56)57)20-33(50)36(47-27(4)49)39(58-43)38(53)34(51)23-46-41(55)31-16-25(2)37(52)26(3)17-31/h5,7-10,13-14,16-18,21,30,32-34,36,38-39,50-53H,6,11-12,15,19-20,22-23H2,1-4H3,(H,44,48)(H,45,54)(H,46,55)(H,47,49)(H,56,57) WYEPXHJJGQTZIS-UHFFFAOYSA-N 778401 US20250313574, Example A-259 Myeloid cell surface antigen CD33 5810 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778401 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778401&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292876 523296748 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560819 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)C4CCCOC4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C44H58N6O11/c1-26-17-32(18-27(2)38(26)54)42(57)46-22-35(52)39(55)40-37(47-36(53)24-50-23-33(48-49-50)30-12-4-3-5-13-30)34(51)20-44(61-40,43(58)59)15-7-11-28-9-6-10-29(19-28)21-45-41(56)31-14-8-16-60-25-31/h6-7,9-11,17-19,23,30-31,34-35,37,39-40,51-52,54-55H,3-5,8,12-16,20-22,24-25H2,1-2H3,(H,45,56)(H,46,57)(H,47,53)(H,58,59) YXBQDOWPMAZBOD-UHFFFAOYSA-N 778402 US20250313574, Example A-260 Myeloid cell surface antigen CD33 7940 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778402 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778402&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292789 523296749 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560820 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)C4CCOCC4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C44H58N6O11/c1-26-18-32(19-27(2)38(26)54)42(57)46-23-35(52)39(55)40-37(47-36(53)25-50-24-33(48-49-50)30-11-4-3-5-12-30)34(51)21-44(61-40,43(58)59)15-7-10-28-8-6-9-29(20-28)22-45-41(56)31-13-16-60-17-14-31/h6-10,18-20,24,30-31,34-35,37,39-40,51-52,54-55H,3-5,11-17,21-23,25H2,1-2H3,(H,45,56)(H,46,57)(H,47,53)(H,58,59) KSAXDRSYFLGGCG-UHFFFAOYSA-N 778403 US20250313574, Example A-261 Myeloid cell surface antigen CD33 1440 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778403 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778403&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893468 523296750 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560821 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4cccc(Cl)c4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C45H53ClN6O10/c1-26-17-32(18-27(2)39(26)56)43(59)48-23-36(54)40(57)41-38(49-37(55)25-52-24-34(50-51-52)30-12-4-3-5-13-30)35(53)21-45(62-41,44(60)61)16-8-11-28-9-6-10-29(19-28)22-47-42(58)31-14-7-15-33(46)20-31/h6-11,14-15,17-20,24,30,35-36,38,40-41,53-54,56-57H,3-5,12-13,16,21-23,25H2,1-2H3,(H,47,58)(H,48,59)(H,49,55)(H,60,61) ZKHFATWKQRXJKY-UHFFFAOYSA-N 778404 US20250313574, Example A-262 Myeloid cell surface antigen CD33 6030 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778404&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292877 523296751 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560822 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4ccc(Cl)cc4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C45H53ClN6O10/c1-26-18-32(19-27(2)39(26)56)43(59)48-23-36(54)40(57)41-38(49-37(55)25-52-24-34(50-51-52)30-11-4-3-5-12-30)35(53)21-45(62-41,44(60)61)17-7-10-28-8-6-9-29(20-28)22-47-42(58)31-13-15-33(46)16-14-31/h6-10,13-16,18-20,24,30,35-36,38,40-41,53-54,56-57H,3-5,11-12,17,21-23,25H2,1-2H3,(H,47,58)(H,48,59)(H,49,55)(H,60,61) DEOUXZZZLVFDFW-UHFFFAOYSA-N 778405 US20250313574, Example A-263 Myeloid cell surface antigen CD33 4000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778405 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778405&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292763 523296752 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560823 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)C4CCCC4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C44H58N6O10/c1-26-18-32(19-27(2)38(26)54)42(57)46-23-35(52)39(55)40-37(47-36(53)25-50-24-33(48-49-50)30-13-4-3-5-14-30)34(51)21-44(60-40,43(58)59)17-9-12-28-10-8-11-29(20-28)22-45-41(56)31-15-6-7-16-31/h8-12,18-20,24,30-31,34-35,37,39-40,51-52,54-55H,3-7,13-17,21-23,25H2,1-2H3,(H,45,56)(H,46,57)(H,47,53)(H,58,59) GRQMNJIHRHCBSD-UHFFFAOYSA-N 778406 US20250313574, Example A-264 Myeloid cell surface antigen CD33 6330 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778406 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778406&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292898 523296753 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560824 COCCC(=O)NCc1cccc(/C=C/C[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)c1 InChI=1S/C42H56N6O11/c1-25-17-30(18-26(2)37(25)53)40(55)44-22-33(50)38(54)39-36(45-35(52)24-48-23-31(46-47-48)29-12-5-4-6-13-29)32(49)20-42(59-39,41(56)57)15-8-11-27-9-7-10-28(19-27)21-43-34(51)14-16-58-3/h7-11,17-19,23,29,32-33,36,38-39,49-50,53-54H,4-6,12-16,20-22,24H2,1-3H3,(H,43,51)(H,44,55)(H,45,52)(H,56,57) ABYZDOPGQVEBSY-UHFFFAOYSA-N 778407 US20250313574, Example A-265 Myeloid cell surface antigen CD33 1370 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778407 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778407&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292897 523296754 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560825 CC(=O)N1CCC(C(=O)NCc2cccc(/C=C/C[C@]3(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn4cc(C5CCCCC5)nn4)[C@H]([C@H](O)[C@H](O)CNC(=O)c4cc(C)c(O)c(C)c4)O3)c2)CC1 InChI=1S/C46H61N7O11/c1-27-19-34(20-28(2)40(27)58)44(61)48-24-37(56)41(59)42-39(49-38(57)26-53-25-35(50-51-53)32-12-5-4-6-13-32)36(55)22-46(64-42,45(62)63)16-8-11-30-9-7-10-31(21-30)23-47-43(60)33-14-17-52(18-15-33)29(3)54/h7-11,19-21,25,32-33,36-37,39,41-42,55-56,58-59H,4-6,12-18,22-24,26H2,1-3H3,(H,47,60)(H,48,61)(H,49,57)(H,62,63) VQYBBAMWQZWXQS-UHFFFAOYSA-N 778408 US20250313574, Example A-266 Myeloid cell surface antigen CD33 1380 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778408 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778408&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292788 523296755 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560826 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)C4CCCO4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C43H56N6O11/c1-25-17-30(18-26(2)37(25)53)40(55)45-22-33(51)38(54)39-36(46-35(52)24-49-23-31(47-48-49)29-12-4-3-5-13-29)32(50)20-43(60-39,42(57)58)15-7-11-27-9-6-10-28(19-27)21-44-41(56)34-14-8-16-59-34/h6-7,9-11,17-19,23,29,32-34,36,38-39,50-51,53-54H,3-5,8,12-16,20-22,24H2,1-2H3,(H,44,56)(H,45,55)(H,46,52)(H,57,58) DEWGZXXLWPDNLY-UHFFFAOYSA-N 778409 US20250313574, Example A-267 Myeloid cell surface antigen CD33 9170 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778409 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778409&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292722 523296756 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560827 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)C4CCCOC4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C44H58N6O11/c1-26-17-32(18-27(2)38(26)54)42(57)46-22-35(52)39(55)40-37(47-36(53)24-50-23-33(48-49-50)30-12-4-3-5-13-30)34(51)20-44(61-40,43(58)59)15-7-11-28-9-6-10-29(19-28)21-45-41(56)31-14-8-16-60-25-31/h6-7,9-11,17-19,23,30-31,34-35,37,39-40,51-52,54-55H,3-5,8,12-16,20-22,24-25H2,1-2H3,(H,45,56)(H,46,57)(H,47,53)(H,58,59) YXBQDOWPMAZBOD-UHFFFAOYSA-N 778410 US20250313574, Example A-268 Myeloid cell surface antigen CD33 1320 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778410 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778410&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292789 523296757 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560828 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4ccccc4C(F)(F)F)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C46H53F3N6O10/c1-26-18-31(19-27(2)39(26)59)42(61)51-23-36(57)40(60)41-38(52-37(58)25-55-24-34(53-54-55)30-13-4-3-5-14-30)35(56)21-45(65-41,44(63)64)17-9-12-28-10-8-11-29(20-28)22-50-43(62)32-15-6-7-16-33(32)46(47,48)49/h6-12,15-16,18-20,24,30,35-36,38,40-41,56-57,59-60H,3-5,13-14,17,21-23,25H2,1-2H3,(H,50,62)(H,51,61)(H,52,58)(H,63,64) OOOMUOUIGWAEAD-UHFFFAOYSA-N 778411 US20250313574, Example A-269 Myeloid cell surface antigen CD33 3460 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778411 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778411&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292839 523296758 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560829 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4cnccn4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C43H52N8O10/c1-25-16-30(17-26(2)37(25)55)40(57)47-22-34(53)38(56)39-36(48-35(54)24-51-23-32(49-50-51)29-11-4-3-5-12-29)33(52)19-43(61-39,42(59)60)13-7-10-27-8-6-9-28(18-27)20-46-41(58)31-21-44-14-15-45-31/h6-10,14-18,21,23,29,33-34,36,38-39,52-53,55-56H,3-5,11-13,19-20,22,24H2,1-2H3,(H,46,58)(H,47,57)(H,48,54)(H,59,60) KBEHFWNGCDYCIS-UHFFFAOYSA-N 778412 US20250313574, Example A-270 Myeloid cell surface antigen CD33 2800 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778412 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778412&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292821 523296759 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560830 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4ccon4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C42H51N7O11/c1-24-16-29(17-25(2)36(24)53)39(55)44-21-33(51)37(54)38-35(45-34(52)23-49-22-31(46-48-49)28-11-4-3-5-12-28)32(50)19-42(60-38,41(57)58)14-7-10-26-8-6-9-27(18-26)20-43-40(56)30-13-15-59-47-30/h6-10,13,15-18,22,28,32-33,35,37-38,50-51,53-54H,3-5,11-12,14,19-21,23H2,1-2H3,(H,43,56)(H,44,55)(H,45,52)(H,57,58) ZFFMPNSJFAVYSH-UHFFFAOYSA-N 778413 US20250313574, Example A-271 Myeloid cell surface antigen CD33 3990 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778413 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778413&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292801 523296760 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560831 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)C4C5OCCC[C@H]54)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C45H58N6O11/c1-25-17-30(18-26(2)38(25)55)42(57)47-22-34(53)39(56)41-37(48-35(54)24-51-23-32(49-50-51)29-12-4-3-5-13-29)33(52)20-45(62-41,44(59)60)15-7-11-27-9-6-10-28(19-27)21-46-43(58)36-31-14-8-16-61-40(31)36/h6-7,9-11,17-19,23,29,31,33-34,36-37,39-41,52-53,55-56H,3-5,8,12-16,20-22,24H2,1-2H3,(H,46,58)(H,47,57)(H,48,54)(H,59,60) YRHJIOFSEGRDEI-UHFFFAOYSA-N 778414 US20250313574, Example A-272 Myeloid cell surface antigen CD33 9640 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778414 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778414&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893469 523296761 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560832 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4ccn(C)c(=O)c4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C45H55N7O11/c1-26-17-32(18-27(2)39(26)57)43(60)47-23-35(54)40(58)41-38(48-36(55)25-52-24-33(49-50-52)30-12-5-4-6-13-30)34(53)21-45(63-41,44(61)62)15-8-11-28-9-7-10-29(19-28)22-46-42(59)31-14-16-51(3)37(56)20-31/h7-11,14,16-20,24,30,34-35,38,40-41,53-54,57-58H,4-6,12-13,15,21-23,25H2,1-3H3,(H,46,59)(H,47,60)(H,48,55)(H,61,62) PNUSKTLZZPZGDU-UHFFFAOYSA-N 778415 US20250313574, Example A-273 Myeloid cell surface antigen CD33 9940 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778415 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778415&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292819 523296762 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560833 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)CC4CCOCC4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C45H60N6O11/c1-27-18-33(19-28(2)40(27)56)43(58)47-24-36(53)41(57)42-39(48-38(55)26-51-25-34(49-50-51)32-11-4-3-5-12-32)35(52)22-45(62-42,44(59)60)15-7-10-29-8-6-9-31(20-29)23-46-37(54)21-30-13-16-61-17-14-30/h6-10,18-20,25,30,32,35-36,39,41-42,52-53,56-57H,3-5,11-17,21-24,26H2,1-2H3,(H,46,54)(H,47,58)(H,48,55)(H,59,60) LEIBYULBLMQXCW-UHFFFAOYSA-N 778416 US20250313574, Example A-274 Myeloid cell surface antigen CD33 4700 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778416 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778416&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292950 523296763 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560834 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4ccn(-c5ccccn5)n4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C47H55N9O10/c1-28-20-33(21-29(2)41(28)60)44(62)50-25-37(58)42(61)43-40(51-39(59)27-55-26-35(52-54-55)32-13-4-3-5-14-32)36(57)23-47(66-43,46(64)65)17-9-12-30-10-8-11-31(22-30)24-49-45(63)34-16-19-56(53-34)38-15-6-7-18-48-38/h6-12,15-16,18-22,26,32,36-37,40,42-43,57-58,60-61H,3-5,13-14,17,23-25,27H2,1-2H3,(H,49,63)(H,50,62)(H,51,59)(H,64,65) ZEVYRSSFQWYQHT-UHFFFAOYSA-N 778417 US20250313574, Example A-275 Myeloid cell surface antigen CD33 8630 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778417 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778417&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292858 523296764 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560835 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4scnc4C)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C43H53N7O10S/c1-24-15-30(16-25(2)36(24)54)40(56)45-20-33(52)37(55)38-35(47-34(53)22-50-21-31(48-49-50)29-12-5-4-6-13-29)32(51)18-43(60-38,42(58)59)14-8-11-27-9-7-10-28(17-27)19-44-41(57)39-26(3)46-23-61-39/h7-11,15-17,21,23,29,32-33,35,37-38,51-52,54-55H,4-6,12-14,18-20,22H2,1-3H3,(H,44,57)(H,45,56)(H,47,53)(H,58,59) OTJQBTMCJBMLED-UHFFFAOYSA-N 778418 US20250313574, Example A-276 Myeloid cell surface antigen CD33 2920 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778418 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778418&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292836 523296765 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560836 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4cn[nH]c4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C42H52N8O10/c1-24-14-29(15-25(2)36(24)54)39(56)44-21-33(52)37(55)38-35(47-34(53)23-50-22-31(48-49-50)28-11-4-3-5-12-28)32(51)17-42(60-38,41(58)59)13-7-10-26-8-6-9-27(16-26)18-43-40(57)30-19-45-46-20-30/h6-10,14-16,19-20,22,28,32-33,35,37-38,51-52,54-55H,3-5,11-13,17-18,21,23H2,1-2H3,(H,43,57)(H,44,56)(H,45,46)(H,47,53)(H,58,59) BLIUOVUQWHUZPQ-UHFFFAOYSA-N 778419 US20250313574, Example A-277 Myeloid cell surface antigen CD33 10240 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778419 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778419&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292893 523296766 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560837 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4ccc5[nH]ccc5c4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C47H55N7O10/c1-27-18-34(19-28(2)41(27)58)45(61)50-24-38(56)42(59)43-40(51-39(57)26-54-25-36(52-53-54)31-11-4-3-5-12-31)37(55)22-47(64-43,46(62)63)16-7-10-29-8-6-9-30(20-29)23-49-44(60)33-13-14-35-32(21-33)15-17-48-35/h6-10,13-15,17-21,25,31,37-38,40,42-43,48,55-56,58-59H,3-5,11-12,16,22-24,26H2,1-2H3,(H,49,60)(H,50,61)(H,51,57)(H,62,63) QCDDLTSAYVPJCD-UHFFFAOYSA-N 778420 US20250313574, Example A-278 Myeloid cell surface antigen CD33 1740 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778420 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778420&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893470 523296767 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560838 COc1cc(C(=O)NCc2cccc(/C=C/C[C@]3(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn4cc(C5CCCCC5)nn4)[C@H]([C@H](O)[C@H](O)CNC(=O)c4cc(C)c(O)c(C)c4)O3)c2)ccc1O InChI=1S/C46H56N6O12/c1-26-17-32(18-27(2)40(26)57)44(60)48-23-36(55)41(58)42-39(49-38(56)25-52-24-33(50-51-52)30-12-5-4-6-13-30)35(54)21-46(64-42,45(61)62)16-8-11-28-9-7-10-29(19-28)22-47-43(59)31-14-15-34(53)37(20-31)63-3/h7-11,14-15,17-20,24,30,35-36,39,41-42,53-55,57-58H,4-6,12-13,16,21-23,25H2,1-3H3,(H,47,59)(H,48,60)(H,49,56)(H,61,62) DKLHHOCKHLJBMV-UHFFFAOYSA-N 778421 US20250313574, Example A-279 Myeloid cell surface antigen CD33 10360 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778421 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778421&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292903 523296768 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560839 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)c4ccc5[nH]cnc5c4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C46H54N8O10/c1-26-16-32(17-27(2)40(26)58)44(61)48-22-37(56)41(59)42-39(51-38(57)24-54-23-35(52-53-54)30-11-4-3-5-12-30)36(55)20-46(64-42,45(62)63)15-7-10-28-8-6-9-29(18-28)21-47-43(60)31-13-14-33-34(19-31)50-25-49-33/h6-10,13-14,16-19,23,25,30,36-37,39,41-42,55-56,58-59H,3-5,11-12,15,20-22,24H2,1-2H3,(H,47,60)(H,48,61)(H,49,50)(H,51,57)(H,62,63) WNBPSVKVXWSJMZ-UHFFFAOYSA-N 778422 US20250313574, Example A-280 Myeloid cell surface antigen CD33 4900 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778422 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778422&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292770 523296769 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560840 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)C4CCC(NS(C)(=O)=O)CC4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C46H63N7O12S/c1-27-19-33(20-28(2)40(27)57)44(60)48-24-37(55)41(58)42-39(49-38(56)26-53-25-35(50-52-53)31-12-5-4-6-13-31)36(54)22-46(65-42,45(61)62)18-8-11-29-9-7-10-30(21-29)23-47-43(59)32-14-16-34(17-15-32)51-66(3,63)64/h7-11,19-21,25,31-32,34,36-37,39,41-42,51,54-55,57-58H,4-6,12-18,22-24,26H2,1-3H3,(H,47,59)(H,48,60)(H,49,56)(H,61,62) KOIIDIHQAUNOFO-UHFFFAOYSA-N 778423 US20250313574, Example A-281 Myeloid cell surface antigen CD33 1520 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778423 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778423&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292749 523296770 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560841 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)C4CCC[C@H](NS(C)(=O)=O)C4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C46H63N7O12S/c1-27-18-33(19-28(2)40(27)57)44(60)48-24-37(55)41(58)42-39(49-38(56)26-53-25-35(50-52-53)31-13-5-4-6-14-31)36(54)22-46(65-42,45(61)62)17-9-12-29-10-7-11-30(20-29)23-47-43(59)32-15-8-16-34(21-32)51-66(3,63)64/h7,9-12,18-20,25,31-32,34,36-37,39,41-42,51,54-55,57-58H,4-6,8,13-17,21-24,26H2,1-3H3,(H,47,59)(H,48,60)(H,49,56)(H,61,62) OXQXBVPWIUYGRU-UHFFFAOYSA-N 778424 US20250313574, Example A-282 Myeloid cell surface antigen CD33 1680 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778424 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778424&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893471 523296771 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560842 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3ccccc3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C37H47N5O9/c1-22-16-26(17-23(2)32(22)46)35(48)38-19-29(44)33(47)34-31(39-30(45)21-42-20-27(40-41-42)25-13-7-4-8-14-25)28(43)18-37(51-34,36(49)50)15-9-12-24-10-5-3-6-11-24/h3,5-6,9-12,16-17,20,25,28-29,31,33-34,43-44,46-47H,4,7-8,13-15,18-19,21H2,1-2H3,(H,38,48)(H,39,45)(H,49,50) RZGUIQPUPRMFRX-UHFFFAOYSA-N 778425 US20250313574, Example A-283 Myeloid cell surface antigen CD33 101900 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778425 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778425&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292716 523296772 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560843 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3ccc4c(c3)C(NC(=O)C3CCCOC3)CC4)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C46H60N6O11/c1-26-18-32(19-27(2)40(26)56)43(58)47-22-37(54)41(57)42-39(49-38(55)24-52-23-35(50-51-52)30-9-4-3-5-10-30)36(53)21-46(63-42,45(60)61)16-6-8-28-12-13-29-14-15-34(33(29)20-28)48-44(59)31-11-7-17-62-25-31/h6,8,12-13,18-20,23,30-31,34,36-37,39,41-42,53-54,56-57H,3-5,7,9-11,14-17,21-22,24-25H2,1-2H3,(H,47,58)(H,48,59)(H,49,55)(H,60,61) FAVINOKIYHHTSG-UHFFFAOYSA-N 778426 US20250313574, Example A-284 Myeloid cell surface antigen CD33 1660 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778426 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778426&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292862 523296773 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560844 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](C/C=C/c3cccc(CNC(=O)OC(C)(C)C)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C43H58N6O11/c1-25-17-30(18-26(2)36(25)53)39(55)44-22-33(51)37(54)38-35(46-34(52)24-49-23-31(47-48-49)29-14-7-6-8-15-29)32(50)20-43(59-38,40(56)57)16-10-13-27-11-9-12-28(19-27)21-45-41(58)60-42(3,4)5/h9-13,17-19,23,29,32-33,35,37-38,50-51,53-54H,6-8,14-16,20-22,24H2,1-5H3,(H,44,55)(H,45,58)(H,46,52)(H,56,57) FFJOJZOUOGVTRQ-UHFFFAOYSA-N 778427 US20250313574, Example A-285 Myeloid cell surface antigen CD33 9980 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778427 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778427&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292799 523296774 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560845 Cc1ccc(CNC(=O)C2CCCOC2)cc1/C=C/C[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn2cc(C3CCCCC3)nn2)[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O1 InChI=1S/C45H60N6O11/c1-26-13-14-29(21-46-42(57)32-12-8-16-61-25-32)19-31(26)11-7-15-45(44(59)60)20-35(52)38(48-37(54)24-51-23-34(49-50-51)30-9-5-4-6-10-30)41(62-45)40(56)36(53)22-47-43(58)33-17-27(2)39(55)28(3)18-33/h7,11,13-14,17-19,23,30,32,35-36,38,40-41,52-53,55-56H,4-6,8-10,12,15-16,20-22,24-25H2,1-3H3,(H,46,57)(H,47,58)(H,48,54)(H,59,60) XCWWMKSSMJVATG-UHFFFAOYSA-N 778428 US20250313574, Example A-286 Myeloid cell surface antigen CD33 2840 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778428 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778428&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292938 523296775 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560846 Cc1ccc(CN(C)C(=O)C2CCCOC2)cc1/C=C/C[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn2cc(C3CCCCC3)nn2)[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O1 InChI=1S/C46H62N6O11/c1-27-14-15-30(23-51(4)44(59)33-13-9-17-62-26-33)20-32(27)12-8-16-46(45(60)61)21-36(53)39(48-38(55)25-52-24-35(49-50-52)31-10-6-5-7-11-31)42(63-46)41(57)37(54)22-47-43(58)34-18-28(2)40(56)29(3)19-34/h8,12,14-15,18-20,24,31,33,36-37,39,41-42,53-54,56-57H,5-7,9-11,13,16-17,21-23,25-26H2,1-4H3,(H,47,58)(H,48,55)(H,60,61) RCDFLZRIHINMMH-UHFFFAOYSA-N 778429 US20250313574, Example A-287 Myeloid cell surface antigen CD33 1160 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778429 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778429&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292906 523296776 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560847 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2ccccc2CNC(=O)OC(C)(C)C)(C(=O)O)C[C@@H]1O InChI=1S/C35H47N3O11/c1-19-14-24(15-20(2)28(19)42)31(44)36-18-26(41)29(43)30-27(38-21(3)39)25(40)16-35(48-30,32(45)46)13-9-12-22-10-7-8-11-23(22)17-37-33(47)49-34(4,5)6/h7-12,14-15,25-27,29-30,40-43H,13,16-18H2,1-6H3,(H,36,44)(H,37,47)(H,38,39)(H,45,46) ORKCQUAPIKLFES-UHFFFAOYSA-N 778430 US20250313574, Example A-288 Myeloid cell surface antigen CD33 2680 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778430 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778430&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893472 523296777 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560848 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cc(CNC(=O)C3CCCOC3)ccc2C)(C(=O)O)C[C@@H]1O InChI=1S/C37H49N3O11/c1-20-9-10-24(17-38-34(46)26-8-6-12-50-19-26)15-25(20)7-5-11-37(36(48)49)16-28(42)30(40-23(4)41)33(51-37)32(45)29(43)18-39-35(47)27-13-21(2)31(44)22(3)14-27/h5,7,9-10,13-15,26,28-30,32-33,42-45H,6,8,11-12,16-19H2,1-4H3,(H,38,46)(H,39,47)(H,40,41)(H,48,49) OCWWYLWCXITKDW-UHFFFAOYSA-N 778431 US20250313574, Example A-289 Myeloid cell surface antigen CD33 2680 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778431&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893473 523296778 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560849 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cc(CNC(=O)C3CCCOC3)ccc2C)(C(=O)O)C[C@@H]1O InChI=1S/C37H49N3O11/c1-20-9-10-24(17-38-34(46)26-8-6-12-50-19-26)15-25(20)7-5-11-37(36(48)49)16-28(42)30(40-23(4)41)33(51-37)32(45)29(43)18-39-35(47)27-13-21(2)31(44)22(3)14-27/h5,7,9-10,13-15,26,28-30,32-33,42-45H,6,8,11-12,16-19H2,1-4H3,(H,38,46)(H,39,47)(H,40,41)(H,48,49) OCWWYLWCXITKDW-UHFFFAOYSA-N 778432 US20250313574, Example A-290 Myeloid cell surface antigen CD33 20400 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778432 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778432&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893473 523296779 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560850 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(-c3cc(N)on3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C32H38N4O10/c1-16-10-21(11-17(2)27(16)40)30(42)34-15-24(39)28(41)29-26(35-18(3)37)23(38)14-32(45-29,31(43)44)9-5-7-19-6-4-8-20(12-19)22-13-25(33)46-36-22/h4-8,10-13,23-24,26,28-29,38-41H,9,14-15,33H2,1-3H3,(H,34,42)(H,35,37)(H,43,44) XUFUZNNIVNYOQV-UHFFFAOYSA-N 778433 US20250313574, Example A-291 Myeloid cell surface antigen CD33 4300 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778433 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778433&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893474 523296780 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560851 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CN(C)C(=O)C3CCCOC3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C37H49N3O11/c1-21-14-27(15-22(2)31(21)44)34(46)38-18-29(43)32(45)33-30(39-23(3)41)28(42)17-37(51-33,36(48)49)12-6-10-24-8-5-9-25(16-24)19-40(4)35(47)26-11-7-13-50-20-26/h5-6,8-10,14-16,26,28-30,32-33,42-45H,7,11-13,17-20H2,1-4H3,(H,38,46)(H,39,41)(H,48,49) RVKABSZHAJWCOQ-UHFFFAOYSA-N 778434 US20250313574, Example A-292 Myeloid cell surface antigen CD33 3020 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778434 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778434&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893475 523296781 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560852 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(CNC(=O)C3CCCOC3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C36H47N3O11/c1-20-13-26(14-21(2)30(20)43)34(46)38-18-28(42)31(44)32-29(39-22(3)40)27(41)16-36(50-32,35(47)48)11-5-9-23-7-4-8-24(15-23)17-37-33(45)25-10-6-12-49-19-25/h4-5,7-9,13-15,25,27-29,31-32,41-44H,6,10-12,16-19H2,1-3H3,(H,37,45)(H,38,46)(H,39,40)(H,47,48) ZNCHNBSUKXFOEK-UHFFFAOYSA-N 778435 US20250313574, Example A-293 Myeloid cell surface antigen CD33 7940 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778435 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778435&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893476 523296782 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560853 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cnc(CNC(=O)C3CCCOC3)s2)(C(=O)O)C[C@@H]1O InChI=1S/C33H44N4O11S/c1-17-10-21(11-18(2)27(17)41)31(44)35-14-24(40)28(42)29-26(37-19(3)38)23(39)12-33(48-29,32(45)46)8-4-7-22-13-34-25(49-22)15-36-30(43)20-6-5-9-47-16-20/h4,7,10-11,13,20,23-24,26,28-29,39-42H,5-6,8-9,12,14-16H2,1-3H3,(H,35,44)(H,36,43)(H,37,38)(H,45,46) OIFRUMFKTORCCI-UHFFFAOYSA-N 778436 US20250313574, Example A-294 Myeloid cell surface antigen CD33 4610 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778436 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778436&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292704 523296783 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560854 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](C/C=C/c2cccc(C3CCCN3C(=O)OC(C)(C)C)c2)(C(=O)O)C[C@@H]1O InChI=1S/C38H51N3O11/c1-21-16-26(17-22(2)31(21)45)34(47)39-20-29(44)32(46)33-30(40-23(3)42)28(43)19-38(51-33,35(48)49)14-8-11-24-10-7-12-25(18-24)27-13-9-15-41(27)36(50)52-37(4,5)6/h7-8,10-12,16-18,27-30,32-33,43-46H,9,13-15,19-20H2,1-6H3,(H,39,47)(H,40,42)(H,48,49) BOSQGRWFTISZLM-UHFFFAOYSA-N 778437 US20250313574, Example A-295 Myeloid cell surface antigen CD33 6640 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778437 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778437&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292912 523296784 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560855 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(NC(=O)OC(C)(C)C)c2)(C(=O)O)C[C@@H]1O InChI=1S/C37H51N3O13/c1-18-12-22(13-19(2)28(18)44)32(46)38-17-25(43)29(45)31-27(39-20(3)41)24(42)15-37(52-31,33(47)48)16-26-30(51-36(7,8)50-26)21-10-9-11-23(14-21)40-34(49)53-35(4,5)6/h9-14,24-27,29-31,42-45H,15-17H2,1-8H3,(H,38,46)(H,39,41)(H,40,49)(H,47,48) DEFVFNSLNXDUKI-UHFFFAOYSA-N 778438 US20250313574, Example A-296 Myeloid cell surface antigen CD33 477 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778438 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778438&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292852 523296785 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560856 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CC3OC(C)(C)O[C@H]3c3cccc(NC(=O)OC(C)(C)C)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C45H62N6O13/c1-24-16-28(17-25(2)36(24)55)40(57)46-21-32(53)37(56)39-35(48-34(54)23-51-22-30(49-50-51)26-12-9-8-10-13-26)31(52)19-45(63-39,41(58)59)20-33-38(62-44(6,7)61-33)27-14-11-15-29(18-27)47-42(60)64-43(3,4)5/h11,14-18,22,26,31-33,35,37-39,52-53,55-56H,8-10,12-13,19-21,23H2,1-7H3,(H,46,57)(H,47,60)(H,48,54)(H,58,59) HAQNHKCBUXWDFB-UHFFFAOYSA-N 778439 US20250313574, Example A-299 Myeloid cell surface antigen CD33 512 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778439 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778439&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292826 523296786 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560857 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CC(O)[C@@H](O)c3cccc(NC(=O)OC(C)(C)C)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C42H58N6O13/c1-22-14-26(15-23(2)34(22)53)38(56)43-19-31(51)36(55)37-33(45-32(52)21-48-20-28(46-47-48)24-10-7-6-8-11-24)29(49)17-42(60-37,39(57)58)18-30(50)35(54)25-12-9-13-27(16-25)44-40(59)61-41(3,4)5/h9,12-16,20,24,29-31,33,35-37,49-51,53-55H,6-8,10-11,17-19,21H2,1-5H3,(H,43,56)(H,44,59)(H,45,52)(H,57,58) CWZMOSYXOCSNRH-UHFFFAOYSA-N 778440 US20250313574, Example A-300 Myeloid cell surface antigen CD33 44600 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778440 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778440&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292712 523296787 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560858 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](CC3OC(C)(C)O[C@H]3c3cccc(CNC(=O)OC(C)(C)C)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C46H64N6O13/c1-25-16-30(17-26(2)37(25)56)41(58)47-22-33(54)38(57)40-36(49-35(55)24-52-23-31(50-51-52)28-13-9-8-10-14-28)32(53)19-46(64-40,42(59)60)20-34-39(63-45(6,7)62-34)29-15-11-12-27(18-29)21-48-43(61)65-44(3,4)5/h11-12,15-18,23,28,32-34,36,38-40,53-54,56-57H,8-10,13-14,19-22,24H2,1-7H3,(H,47,58)(H,48,61)(H,49,55)(H,59,60) NSGLGWFIMNZQJC-UHFFFAOYSA-N 778441 US20250313574, Example A-301 Myeloid cell surface antigen CD33 5260 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778441 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778441&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893477 523296788 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560859 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(NC(=O)c3ccc4cc[nH]c4c3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C41H48N4O12/c1-20-13-26(14-21(2)33(20)49)37(51)43-19-30(48)34(50)36-32(44-22(3)46)29(47)17-41(57-36,39(53)54)18-31-35(56-40(4,5)55-31)24-7-6-8-27(15-24)45-38(52)25-10-9-23-11-12-42-28(23)16-25/h6-16,29-32,34-36,42,47-50H,17-19H2,1-5H3,(H,43,51)(H,44,46)(H,45,52)(H,53,54) AWGYKDBMSQOTPK-UHFFFAOYSA-N 778442 US20250313574, Example A-302 Myeloid cell surface antigen CD33 1500 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778442 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778442&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893478 523296789 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560860 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(NC(=O)CC(C)(C)C)c2)(C(=O)O)C[C@@H]1O InChI=1S/C38H53N3O12/c1-19-12-23(13-20(2)30(19)46)34(48)39-18-26(44)31(47)33-29(40-21(3)42)25(43)15-38(53-33,35(49)50)16-27-32(52-37(7,8)51-27)22-10-9-11-24(14-22)41-28(45)17-36(4,5)6/h9-14,25-27,29,31-33,43-44,46-47H,15-18H2,1-8H3,(H,39,48)(H,40,42)(H,41,45)(H,49,50) KPQPHJYOSDGMRA-UHFFFAOYSA-N 778443 US20250313574, Example A-303 Myeloid cell surface antigen CD33 1500 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778443 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778443&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893479 523296790 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560861 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC(O)[C@@H](O)c2cccc(NC(=O)CC(C)(C)C)c2)(C(=O)O)C[C@@H]1O InChI=1S/C35H49N3O12/c1-17-10-21(11-18(2)28(17)44)32(47)36-16-25(42)30(46)31-27(37-19(3)39)23(40)13-35(50-31,33(48)49)14-24(41)29(45)20-8-7-9-22(12-20)38-26(43)15-34(4,5)6/h7-12,23-25,27,29-31,40-42,44-46H,13-16H2,1-6H3,(H,36,47)(H,37,39)(H,38,43)(H,48,49) BQAWMZMYXSMVSE-UHFFFAOYSA-N 778444 US20250313574, Example A-304 Myeloid cell surface antigen CD33 4700 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778444 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778444&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893480 523296791 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560862 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(NC(=O)C(=O)[C@H](C)c3cc(C4CC4)no3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C42H52N4O14/c1-19-12-25(13-20(2)33(19)50)38(53)43-18-29(49)35(52)37-32(44-22(4)47)28(48)16-42(59-37,40(55)56)17-31-36(58-41(5,6)57-31)24-8-7-9-26(14-24)45-39(54)34(51)21(3)30-15-27(46-60-30)23-10-11-23/h7-9,12-15,21,23,28-29,31-32,35-37,48-50,52H,10-11,16-18H2,1-6H3,(H,43,53)(H,44,47)(H,45,54)(H,55,56) XLWJSIMLWHXCSJ-UHFFFAOYSA-N 778445 US20250313574, Example A-305 Myeloid cell surface antigen CD33 792 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778445 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778445&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893481 523296792 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560863 C#C[C@H](C)C(=O)C(=O)Nc1cccc([C@@H]2OC(C)(C)OC2C[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)c1 InChI=1S/C38H47N3O13/c1-8-18(2)30(46)35(49)41-24-11-9-10-22(14-24)32-27(52-37(6,7)53-32)16-38(36(50)51)15-25(43)28(40-21(5)42)33(54-38)31(47)26(44)17-39-34(48)23-12-19(3)29(45)20(4)13-23/h1,9-14,18,25-28,31-33,43-45,47H,15-17H2,2-7H3,(H,39,48)(H,40,42)(H,41,49)(H,50,51) IDOFYKSMPCOBCR-UHFFFAOYSA-N 778446 US20250313574, Example A-306 Myeloid cell surface antigen CD33 5620 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778446 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778446&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893482 523296793 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560864 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2COC(C)(C)O2)(C(=O)O)C[C@@H]1O InChI=1S/C26H38N2O11/c1-12-6-15(7-13(2)20(12)32)23(34)27-10-18(31)21(33)22-19(28-14(3)29)17(30)9-26(39-22,24(35)36)8-16-11-37-25(4,5)38-16/h6-7,16-19,21-22,30-33H,8-11H2,1-5H3,(H,27,34)(H,28,29)(H,35,36) KFJNKBMJVKCJPE-UHFFFAOYSA-N 778447 US20250313574, Example A-307 Myeloid cell surface antigen CD33 103000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778447 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778447&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893483 523296794 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560865 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2ccc3c(c2)N(C(=O)OC(C)(C)C)CC3)(C(=O)O)C[C@@H]1O InChI=1S/C39H53N3O13/c1-19-13-24(14-20(2)30(19)46)34(48)40-18-27(45)31(47)33-29(41-21(3)43)26(44)16-39(54-33,35(49)50)17-28-32(53-38(7,8)52-28)23-10-9-22-11-12-42(25(22)15-23)36(51)55-37(4,5)6/h9-10,13-15,26-29,31-33,44-47H,11-12,16-18H2,1-8H3,(H,40,48)(H,41,43)(H,49,50) OSJSAOVRTWLZER-UHFFFAOYSA-N 778448 US20250313574, Example A-308 Myeloid cell surface antigen CD33 2940 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778448 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778448&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893484 523296795 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560866 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(N3CCCC3=O)c2)(C(=O)O)C[C@@H]1O InChI=1S/C36H47N3O12/c1-18-12-22(13-19(2)29(18)44)33(46)37-17-25(42)30(45)32-28(38-20(3)40)24(41)15-36(51-32,34(47)48)16-26-31(50-35(4,5)49-26)21-8-6-9-23(14-21)39-11-7-10-27(39)43/h6,8-9,12-14,24-26,28,30-32,41-42,44-45H,7,10-11,15-17H2,1-5H3,(H,37,46)(H,38,40)(H,47,48) LXQBRBVXXBMNNZ-UHFFFAOYSA-N 778449 US20250313574, Example A-309 Myeloid cell surface antigen CD33 540 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778449 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778449&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893485 523296796 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560867 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2ccccc2CNC(=O)OC(C)(C)C)(C(=O)O)C[C@@H]1O InChI=1S/C38H53N3O13/c1-19-13-23(14-20(2)29(19)45)33(47)39-18-26(44)30(46)32-28(41-21(3)42)25(43)15-38(53-32,34(48)49)16-27-31(52-37(7,8)51-27)24-12-10-9-11-22(24)17-40-35(50)54-36(4,5)6/h9-14,25-28,30-32,43-46H,15-18H2,1-8H3,(H,39,47)(H,40,50)(H,41,42)(H,48,49) MIKRHGVRMBALIS-UHFFFAOYSA-N 778450 US20250313574, Example A-310 Myeloid cell surface antigen CD33 3240 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778450 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778450&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893486 523296797 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560868 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(C(=O)NCc3ccccc3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C40H49N3O12/c1-21-14-27(15-22(2)32(21)47)37(50)42-20-29(46)33(48)35-31(43-23(3)44)28(45)17-40(55-35,38(51)52)18-30-34(54-39(4,5)53-30)25-12-9-13-26(16-25)36(49)41-19-24-10-7-6-8-11-24/h6-16,28-31,33-35,45-48H,17-20H2,1-5H3,(H,41,49)(H,42,50)(H,43,44)(H,51,52) FRMDURWCWPDNQB-UHFFFAOYSA-N 778451 US20250313574, Example A-311 Myeloid cell surface antigen CD33 6360 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778451 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778451&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893487 523296798 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560869 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@@H]2c2cccc(C(=O)NCc3ccccc3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C40H49N3O12/c1-21-14-27(15-22(2)32(21)47)37(50)42-20-29(46)33(48)35-31(43-23(3)44)28(45)17-40(55-35,38(51)52)18-30-34(54-39(4,5)53-30)25-12-9-13-26(16-25)36(49)41-19-24-10-7-6-8-11-24/h6-16,28-31,33-35,45-48H,17-20H2,1-5H3,(H,41,49)(H,42,50)(H,43,44)(H,51,52) FRMDURWCWPDNQB-UHFFFAOYSA-N 778452 US20250313574, Example A-312 Myeloid cell surface antigen CD33 159 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778452 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778452&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893488 523296799 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560870 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(CN3CCOCC3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C37H51N3O12/c1-20-13-25(14-21(2)30(20)44)34(46)38-18-27(43)31(45)33-29(39-22(3)41)26(42)16-37(52-33,35(47)48)17-28-32(51-36(4,5)50-28)24-8-6-7-23(15-24)19-40-9-11-49-12-10-40/h6-8,13-15,26-29,31-33,42-45H,9-12,16-19H2,1-5H3,(H,38,46)(H,39,41)(H,47,48) XXPQDCNBCWCTKX-UHFFFAOYSA-N 778453 US20250313574, Example A-313 Myeloid cell surface antigen CD33 11900 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778453 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778453&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893489 523296800 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560871 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc3c2CN(C(=O)OC(C)(C)C)C3)(C(=O)O)C[C@@H]1O InChI=1S/C39H53N3O13/c1-19-12-23(13-20(2)30(19)46)34(48)40-16-27(45)31(47)33-29(41-21(3)43)26(44)14-39(54-33,35(49)50)15-28-32(53-38(7,8)52-28)24-11-9-10-22-17-42(18-25(22)24)36(51)55-37(4,5)6/h9-13,26-29,31-33,44-47H,14-18H2,1-8H3,(H,40,48)(H,41,43)(H,49,50) JRZZXCNEOUBBEN-UHFFFAOYSA-N 778454 US20250313574, Example A-314 Myeloid cell surface antigen CD33 7850 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778454 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778454&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893490 523296801 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560872 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(CC(=O)OC(C)(C)C)c2)(C(=O)O)C[C@@H]1O InChI=1S/C38H52N2O13/c1-19-12-24(13-20(2)30(19)45)34(47)39-18-26(43)31(46)33-29(40-21(3)41)25(42)16-38(53-33,35(48)49)17-27-32(52-37(7,8)50-27)23-11-9-10-22(14-23)15-28(44)51-36(4,5)6/h9-14,25-27,29,31-33,42-43,45-46H,15-18H2,1-8H3,(H,39,47)(H,40,41)(H,48,49) ZTTOZPHTCJGVCI-UHFFFAOYSA-N 778455 US20250313574, Example A-315 Myeloid cell surface antigen CD33 1140 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778455 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778455&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893491 523296802 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560873 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(N3CCCCC3=O)c2)(C(=O)O)C[C@@H]1O InChI=1S/C37H49N3O12/c1-19-13-23(14-20(2)30(19)45)34(47)38-18-26(43)31(46)33-29(39-21(3)41)25(42)16-37(52-33,35(48)49)17-27-32(51-36(4,5)50-27)22-9-8-10-24(15-22)40-12-7-6-11-28(40)44/h8-10,13-15,25-27,29,31-33,42-43,45-46H,6-7,11-12,16-18H2,1-5H3,(H,38,47)(H,39,41)(H,48,49) HIXWZTGQMJSICU-UHFFFAOYSA-N 778456 US20250313574, Example A-316 Myeloid cell surface antigen CD33 4860 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778456 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778456&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893492 523296803 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560874 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2ccc(F)c(N3CCCC3=O)c2)(C(=O)O)C[C@@H]1O InChI=1S/C36H46FN3O12/c1-17-11-21(12-18(2)29(17)45)33(47)38-16-25(43)30(46)32-28(39-19(3)41)24(42)14-36(52-32,34(48)49)15-26-31(51-35(4,5)50-26)20-8-9-22(37)23(13-20)40-10-6-7-27(40)44/h8-9,11-13,24-26,28,30-32,42-43,45-46H,6-7,10,14-16H2,1-5H3,(H,38,47)(H,39,41)(H,48,49) DJURHMNUISRYRD-UHFFFAOYSA-N 778457 US20250313574, Example A-317 Myeloid cell surface antigen CD33 920 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778457 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778457&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893493 523296804 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560875 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cc(N3CCCC3=O)ccc2C)(C(=O)O)C[C@@H]1O InChI=1S/C37H49N3O12/c1-18-9-10-23(40-11-7-8-28(40)44)14-24(18)32-27(50-36(5,6)51-32)16-37(35(48)49)15-25(42)29(39-21(4)41)33(52-37)31(46)26(43)17-38-34(47)22-12-19(2)30(45)20(3)13-22/h9-10,12-14,25-27,29,31-33,42-43,45-46H,7-8,11,15-17H2,1-6H3,(H,38,47)(H,39,41)(H,48,49) RLQUREWPCMTHAO-UHFFFAOYSA-N 778458 US20250313574, Example A-318 Myeloid cell surface antigen CD33 130 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778458 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778458&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893494 523296805 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560876 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2ccc(C)c(N3CCCC3=O)c2)(C(=O)O)C[C@@H]1O InChI=1S/C37H49N3O12/c1-18-9-10-22(14-24(18)40-11-7-8-28(40)44)32-27(50-36(5,6)51-32)16-37(35(48)49)15-25(42)29(39-21(4)41)33(52-37)31(46)26(43)17-38-34(47)23-12-19(2)30(45)20(3)13-23/h9-10,12-14,25-27,29,31-33,42-43,45-46H,7-8,11,15-17H2,1-6H3,(H,38,47)(H,39,41)(H,48,49) BHVKVNJCZXYGQF-UHFFFAOYSA-N 778459 US20250313574, Example A-319 Myeloid cell surface antigen CD33 4220 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778459 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778459&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893495 523296806 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560877 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CC2OC(C)(C)O[C@@H]2c2ccc(C)c(N3CCCC3=O)c2)(C(=O)O)C[C@@H]1O InChI=1S/C37H49N3O12/c1-18-9-10-22(14-24(18)40-11-7-8-28(40)44)32-27(50-36(5,6)51-32)16-37(35(48)49)15-25(42)29(39-21(4)41)33(52-37)31(46)26(43)17-38-34(47)23-12-19(2)30(45)20(3)13-23/h9-10,12-14,25-27,29,31-33,42-43,45-46H,7-8,11,15-17H2,1-6H3,(H,38,47)(H,39,41)(H,48,49) BHVKVNJCZXYGQF-UHFFFAOYSA-N 778460 US20250313574, Example A-320 Myeloid cell surface antigen CD33 960 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778460 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778460&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893496 523296807 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560878 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(Cl)c(O)c(Cl)c2)O[C@@](CC2OC(C)(C)O[C@H]2c2cccc(C(=O)NCc3ccccc3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C38H43Cl2N3O12/c1-19(44)43-29-26(45)15-38(36(51)52,55-33(29)31(48)27(46)18-42-35(50)23-13-24(39)30(47)25(40)14-23)16-28-32(54-37(2,3)53-28)21-10-7-11-22(12-21)34(49)41-17-20-8-5-4-6-9-20/h4-14,26-29,31-33,45-48H,15-18H2,1-3H3,(H,41,49)(H,42,50)(H,43,44)(H,51,52) ZGWIGCAWSIFDDK-UHFFFAOYSA-N 778461 US20250313574, Example A-321 Myeloid cell surface antigen CD33 220 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778461 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778461&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893497 523296808 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560879 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(Cl)c(O)c(Cl)c2)O[C@@](CC2OC(C)(C)O[C@@H]2c2cccc(C(=O)NCc3ccccc3)c2)(C(=O)O)C[C@@H]1O InChI=1S/C38H43Cl2N3O12/c1-19(44)43-29-26(45)15-38(36(51)52,55-33(29)31(48)27(46)18-42-35(50)23-13-24(39)30(47)25(40)14-23)16-28-32(54-37(2,3)53-28)21-10-7-11-22(12-21)34(49)41-17-20-8-5-4-6-9-20/h4-14,26-29,31-33,45-48H,15-18H2,1-3H3,(H,41,49)(H,42,50)(H,43,44)(H,51,52) ZGWIGCAWSIFDDK-UHFFFAOYSA-N 778462 US20250313574, Example A-322 Myeloid cell surface antigen CD33 7790 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778462 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778462&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893498 523296809 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560880 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OCCOCCNC(=O)OCc3ccccc3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C40H54N6O13/c1-24-17-28(18-25(2)34(24)50)37(52)42-20-31(48)35(51)36-33(43-32(49)22-46-21-29(44-45-46)27-11-7-4-8-12-27)30(47)19-40(59-36,38(53)54)58-16-15-56-14-13-41-39(55)57-23-26-9-5-3-6-10-26/h3,5-6,9-10,17-18,21,27,30-31,33,35-36,47-48,50-51H,4,7-8,11-16,19-20,22-23H2,1-2H3,(H,41,55)(H,42,52)(H,43,49)(H,53,54) QOXXMCPMMFXRDR-UHFFFAOYSA-N 778463 US20250313574, Example A-323 Myeloid cell surface antigen CD33 10900 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778463 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778463&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292882 523296810 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560881 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)CNC(=O)OCc3ccccc3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C44H59N7O13/c1-25-17-29(18-26(2)38(25)56)41(58)45-20-33(53)39(57)40-37(48-36(55)23-51-22-31(49-50-51)28-13-7-4-8-14-28)32(52)19-44(64-40,42(59)60)63-34-16-10-9-15-30(34)47-35(54)21-46-43(61)62-24-27-11-5-3-6-12-27/h3,5-6,11-12,17-18,22,28,30,32-34,37,39-40,52-53,56-57H,4,7-10,13-16,19-21,23-24H2,1-2H3,(H,45,58)(H,46,61)(H,47,54)(H,48,55)(H,59,60) PTTKDIOFMJCAJI-UHFFFAOYSA-N 778464 US20250313574, Example A-324 Myeloid cell surface antigen CD33 3670 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778464 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778464&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292812 523296811 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560882 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)CN(C)C(=O)OCc3ccccc3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C45H61N7O13/c1-26-18-30(19-27(2)39(26)57)42(59)46-21-34(54)40(58)41-38(48-37(56)24-52-22-32(49-50-52)29-14-8-5-9-15-29)33(53)20-45(65-41,43(60)61)64-35-17-11-10-16-31(35)47-36(55)23-51(3)44(62)63-25-28-12-6-4-7-13-28/h4,6-7,12-13,18-19,22,29,31,33-35,38,40-41,53-54,57-58H,5,8-11,14-17,20-21,23-25H2,1-3H3,(H,46,59)(H,47,55)(H,48,56)(H,60,61) IBKBUOFSZOKRJH-UHFFFAOYSA-N 778465 US20250313574, Example A-325 Myeloid cell surface antigen CD33 13200 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778465 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778465&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292954 523296812 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560883 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)CN(C)C(=O)OCc3cccc(C(=O)NC4CC4)c3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C49H66N8O14/c1-27-18-32(19-28(2)42(27)62)45(64)50-22-37(59)43(63)44-41(53-40(61)25-57-23-35(54-55-57)30-11-5-4-6-12-30)36(58)21-49(71-44,47(66)67)70-38-15-8-7-14-34(38)52-39(60)24-56(3)48(68)69-26-29-10-9-13-31(20-29)46(65)51-33-16-17-33/h9-10,13,18-20,23,30,33-34,36-38,41,43-44,58-59,62-63H,4-8,11-12,14-17,21-22,24-26H2,1-3H3,(H,50,64)(H,51,65)(H,52,60)(H,53,61)(H,66,67) WDYKZTRCXQOSIH-UHFFFAOYSA-N 778466 US20250313574, Example A-326 Myeloid cell surface antigen CD33 13600 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778466 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778466&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893499 523296813 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560884 CNC(=O)c1cccc(COC(=O)NCC(=O)NC2CCCCC2O[C@]2(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@H]([C@H](O)[C@H](O)CNC(=O)c3cc(C)c(O)c(C)c3)O2)c1 InChI=1S/C46H62N8O14/c1-25-16-30(17-26(2)39(25)59)43(62)48-20-34(56)40(60)41-38(51-37(58)23-54-22-32(52-53-54)28-11-5-4-6-12-28)33(55)19-46(68-41,44(63)64)67-35-15-8-7-14-31(35)50-36(57)21-49-45(65)66-24-27-10-9-13-29(18-27)42(61)47-3/h9-10,13,16-18,22,28,31,33-35,38,40-41,55-56,59-60H,4-8,11-12,14-15,19-21,23-24H2,1-3H3,(H,47,61)(H,48,62)(H,49,65)(H,50,57)(H,51,58)(H,63,64) NNBFVVFGUDOGOS-UHFFFAOYSA-N 778467 US20250313574, Example A-327 Myeloid cell surface antigen CD33 6610 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778467 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778467&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893500 523296814 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560885 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)CNC(=O)CC3CCOCC3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C43H63N7O13/c1-24-16-28(17-25(2)38(24)56)41(58)45-20-32(52)39(57)40-37(47-36(55)23-50-22-30(48-49-50)27-8-4-3-5-9-27)31(51)19-43(63-40,42(59)60)62-33-11-7-6-10-29(33)46-35(54)21-44-34(53)18-26-12-14-61-15-13-26/h16-17,22,26-27,29,31-33,37,39-40,51-52,56-57H,3-15,18-21,23H2,1-2H3,(H,44,53)(H,45,58)(H,46,54)(H,47,55)(H,59,60) QPMFRQHTBXJVBV-UHFFFAOYSA-N 778468 US20250313574, Example A-328 Myeloid cell surface antigen CD33 12300 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778468 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778468&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893501 523296815 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560886 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)CNC(=O)COC3CCCC3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C43H63N7O13/c1-24-16-27(17-25(2)38(24)56)41(58)45-19-32(52)39(57)40-37(47-35(54)22-50-21-30(48-49-50)26-10-4-3-5-11-26)31(51)18-43(63-40,42(59)60)62-33-15-9-8-14-29(33)46-34(53)20-44-36(55)23-61-28-12-6-7-13-28/h16-17,21,26,28-29,31-33,37,39-40,51-52,56-57H,3-15,18-20,22-23H2,1-2H3,(H,44,55)(H,45,58)(H,46,53)(H,47,54)(H,59,60) KGNZRALPPSZFAZ-UHFFFAOYSA-N 778469 US20250313574, Example A-329 Myeloid cell surface antigen CD33 15200 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778469 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778469&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893502 523296816 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560887 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)Cn3cc(CNC(=O)c4cccc(C#N)c4)nn3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C47H59N11O12/c1-26-15-31(16-27(2)41(26)63)45(66)50-21-36(60)42(64)43-40(52-39(62)25-58-23-34(54-56-58)29-10-4-3-5-11-29)35(59)18-47(70-43,46(67)68)69-37-14-7-6-13-33(37)51-38(61)24-57-22-32(53-55-57)20-49-44(65)30-12-8-9-28(17-30)19-48/h8-9,12,15-17,22-23,29,33,35-37,40,42-43,59-60,63-64H,3-7,10-11,13-14,18,20-21,24-25H2,1-2H3,(H,49,65)(H,50,66)(H,51,61)(H,52,62)(H,67,68) PJVQWHMWUHIRTJ-UHFFFAOYSA-N 778470 US20250313574, Example A-330 Myeloid cell surface antigen CD33 4810 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778470 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778470&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292955 523296817 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560888 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)Cn3cc(Cn4ncc5ccccc5c4=O)nn3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C47H59N11O12/c1-26-16-30(17-27(2)41(26)63)44(65)48-20-36(60)42(64)43-40(51-39(62)25-57-23-34(53-55-57)28-10-4-3-5-11-28)35(59)18-47(70-43,46(67)68)69-37-15-9-8-14-33(37)50-38(61)24-56-21-31(52-54-56)22-58-45(66)32-13-7-6-12-29(32)19-49-58/h6-7,12-13,16-17,19,21,23,28,33,35-37,40,42-43,59-60,63-64H,3-5,8-11,14-15,18,20,22,24-25H2,1-2H3,(H,48,65)(H,50,61)(H,51,62)(H,67,68) LPDXQEZZZJUMQO-UHFFFAOYSA-N 778471 US20250313574, Example A-331 Myeloid cell surface antigen CD33 4330 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778471 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778471&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292814 523296818 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560889 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)Cn3cc(CNC(=O)c4ccccn4)nn3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C45H59N11O12/c1-25-16-28(17-26(2)39(25)61)42(63)48-20-34(58)40(62)41-38(50-37(60)24-56-22-32(52-54-56)27-10-4-3-5-11-27)33(57)18-45(68-41,44(65)66)67-35-14-7-6-12-30(35)49-36(59)23-55-21-29(51-53-55)19-47-43(64)31-13-8-9-15-46-31/h8-9,13,15-17,21-22,27,30,33-35,38,40-41,57-58,61-62H,3-7,10-12,14,18-20,23-24H2,1-2H3,(H,47,64)(H,48,63)(H,49,59)(H,50,60)(H,65,66) OVLJTZYCSBPJLW-UHFFFAOYSA-N 778472 US20250313574, Example A-332 Myeloid cell surface antigen CD33 2300 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778472 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778472&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292828 523296819 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560890 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)Cn3cc(-c4ccccc4)nn3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C44H57N9O11/c1-25-17-29(18-26(2)39(25)58)42(60)45-20-34(55)40(59)41-38(47-37(57)24-53-22-32(49-51-53)28-13-7-4-8-14-28)33(54)19-44(64-41,43(61)62)63-35-16-10-9-15-30(35)46-36(56)23-52-21-31(48-50-52)27-11-5-3-6-12-27/h3,5-6,11-12,17-18,21-22,28,30,33-35,38,40-41,54-55,58-59H,4,7-10,13-16,19-20,23-24H2,1-2H3,(H,45,60)(H,46,56)(H,47,57)(H,61,62) BITYAXHHIHDHFU-UHFFFAOYSA-N 778473 US20250313574, Example A-333 Myeloid cell surface antigen CD33 12200 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778473 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778473&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292741 523296820 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560891 Cc1cc(C(=O)NC[C@@H](O)[C@@H](O)[C@@H]2O[C@@](OC3CCCCC3NC(=O)Cn3cc(CNC(=O)N4CCOCC4)nn3)(C(=O)O)C[C@H](O)[C@H]2NC(=O)Cn2cc(C3CCCCC3)nn2)cc(C)c1O InChI=1S/C44H63N11O13/c1-25-16-28(17-26(2)38(25)60)41(62)45-20-33(57)39(61)40-37(48-36(59)24-55-22-31(50-52-55)27-8-4-3-5-9-27)32(56)18-44(68-40,42(63)64)67-34-11-7-6-10-30(34)47-35(58)23-54-21-29(49-51-54)19-46-43(65)53-12-14-66-15-13-53/h16-17,21-22,27,30,32-34,37,39-40,56-57,60-61H,3-15,18-20,23-24H2,1-2H3,(H,45,62)(H,46,65)(H,47,58)(H,48,59)(H,63,64) BOEAHJFQYQMCRD-UHFFFAOYSA-N 778474 US20250313574, Example A-334 Myeloid cell surface antigen CD33 7700 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778474 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778474&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292924 523296821 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560892 Cc1cc2cc(C)c1OCCCOC[C@H](NC(=O)C1CCCOC1)COC/C=C/C[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C44H64N6O13/c1-27-18-31-19-28(2)39(27)62-17-9-16-61-26-32(46-42(56)30-12-8-15-59-24-30)25-60-14-7-6-13-44(43(57)58)20-34(51)37(40(63-44)38(54)35(52)21-45-41(31)55)47-36(53)23-50-22-33(48-49-50)29-10-4-3-5-11-29/h6-7,18-19,22,29-30,32,34-35,37-38,40,51-52,54H,3-5,8-17,20-21,23-26H2,1-2H3,(H,45,55)(H,46,56)(H,47,53)(H,57,58) MWAOXXAKMLEBFV-UHFFFAOYSA-N 778475 US20250313574, Example A-335 Myeloid cell surface antigen CD33 601 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778475 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778475&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292796 523296822 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560893 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/COC[C@@H](NC(=O)[C@@H]3CCCOC3)COCCCOc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C36H53N3O13/c1-21-14-25-15-22(2)31(21)51-13-7-12-50-20-26(39-34(45)24-8-6-11-48-18-24)19-49-10-5-4-9-36(35(46)47)16-27(41)29(38-23(3)40)32(52-36)30(43)28(42)17-37-33(25)44/h4-5,14-15,24,26-30,32,41-43H,6-13,16-20H2,1-3H3,(H,37,44)(H,38,40)(H,39,45)(H,46,47) XRXHAOKGUHVNNF-UHFFFAOYSA-N 778476 US20250313574, Example A-336 Myeloid cell surface antigen CD33 4190 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778476 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778476&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893503 523296823 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560894 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/COC[C@@H](NC(=O)[C@H]3CCCOC3)COCCCOc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C36H53N3O13/c1-21-14-25-15-22(2)31(21)51-13-7-12-50-20-26(39-34(45)24-8-6-11-48-18-24)19-49-10-5-4-9-36(35(46)47)16-27(41)29(38-23(3)40)32(52-36)30(43)28(42)17-37-33(25)44/h4-5,14-15,24,26-30,32,41-43H,6-13,16-20H2,1-3H3,(H,37,44)(H,38,40)(H,39,45)(H,46,47) XRXHAOKGUHVNNF-UHFFFAOYSA-N 778477 US20250313574, Example A-337 Myeloid cell surface antigen CD33 14130 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778477 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778477&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292771 523296824 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560895 Cc1cc2cc(C)c1OCCOC[C@@H](NC(=O)C1CCCOC1)COC/C=C/C[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C43H62N6O13/c1-26-17-30-18-27(2)38(26)61-16-15-60-25-31(45-41(55)29-11-8-14-58-23-29)24-59-13-7-6-12-43(42(56)57)19-33(50)36(39(62-43)37(53)34(51)20-44-40(30)54)46-35(52)22-49-21-32(47-48-49)28-9-4-3-5-10-28/h6-7,17-18,21,28-29,31,33-34,36-37,39,50-51,53H,3-5,8-16,19-20,22-25H2,1-2H3,(H,44,54)(H,45,55)(H,46,52)(H,56,57) FVBRBPUBYWRJSZ-UHFFFAOYSA-N 778478 US20250313574, Example A-338 Myeloid cell surface antigen CD33 3820 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778478 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778478&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292929 523296825 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560896 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/COC[C@H](NC(=O)C3CCCOC3)COCCOc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C35H51N3O13/c1-20-13-24-14-21(2)30(20)50-12-11-49-19-25(38-33(44)23-7-6-10-47-17-23)18-48-9-5-4-8-35(34(45)46)15-26(40)28(37-22(3)39)31(51-35)29(42)27(41)16-36-32(24)43/h4-5,13-14,23,25-29,31,40-42H,6-12,15-19H2,1-3H3,(H,36,43)(H,37,39)(H,38,44)(H,45,46) KXMSLUSNLDUEJF-UHFFFAOYSA-N 778479 US20250313574, Example A-339 Myeloid cell surface antigen CD33 5910 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778479 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778479&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292918 523296826 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560897 Cc1cc2cc(C)c1OCCOC[C@@H](NC(=O)C1CCCOC1)COCCCC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C43H64N6O13/c1-26-17-30-18-27(2)38(26)61-16-15-60-25-31(45-41(55)29-11-8-14-58-23-29)24-59-13-7-6-12-43(42(56)57)19-33(50)36(39(62-43)37(53)34(51)20-44-40(30)54)46-35(52)22-49-21-32(47-48-49)28-9-4-3-5-10-28/h17-18,21,28-29,31,33-34,36-37,39,50-51,53H,3-16,19-20,22-25H2,1-2H3,(H,44,54)(H,45,55)(H,46,52)(H,56,57) FSQDMYCUNAABET-UHFFFAOYSA-N 778480 US20250313574, Example A-340 Myeloid cell surface antigen CD33 3500 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778480 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778480&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292879 523296827 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560898 Cc1cc2cc(C)c1OCCOC[C@@H](NC(=O)C1CCCOC1)COC/C=C/C[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C43H62N6O13/c1-26-17-30-18-27(2)38(26)61-16-15-60-25-31(45-41(55)29-11-8-14-58-23-29)24-59-13-7-6-12-43(42(56)57)19-33(50)36(39(62-43)37(53)34(51)20-44-40(30)54)46-35(52)22-49-21-32(47-48-49)28-9-4-3-5-10-28/h6-7,17-18,21,28-29,31,33-34,36-37,39,50-51,53H,3-5,8-16,19-20,22-25H2,1-2H3,(H,44,54)(H,45,55)(H,46,52)(H,56,57) FVBRBPUBYWRJSZ-UHFFFAOYSA-N 778481 US20250313574, Example A-341 Myeloid cell surface antigen CD33 9980 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778481 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778481&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292929 523296828 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560899 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(CCCCOC[C@@H](NC(=O)C3CCCOC3)COCCOc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C35H53N3O13/c1-20-13-24-14-21(2)30(20)50-12-11-49-19-25(38-33(44)23-7-6-10-47-17-23)18-48-9-5-4-8-35(34(45)46)15-26(40)28(37-22(3)39)31(51-35)29(42)27(41)16-36-32(24)43/h13-14,23,25-29,31,40-42H,4-12,15-19H2,1-3H3,(H,36,43)(H,37,39)(H,38,44)(H,45,46) HHLHCKKIOGPDPZ-UHFFFAOYSA-N 778482 US20250313574, Example A-342 Myeloid cell surface antigen CD33 45400 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778482 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778482&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292936 523296829 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560900 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/COC[C@@H](NC(=O)OC(C)(C)C)COCCCOc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C35H53N3O13/c1-20-14-23-15-21(2)29(20)49-13-9-12-48-19-24(38-33(46)51-34(4,5)6)18-47-11-8-7-10-35(32(44)45)16-25(40)27(37-22(3)39)30(50-35)28(42)26(41)17-36-31(23)43/h7-8,14-15,24-28,30,40-42H,9-13,16-19H2,1-6H3,(H,36,43)(H,37,39)(H,38,46)(H,44,45) LVAOVERDMKLSCS-UHFFFAOYSA-N 778483 US20250313574, Example A-343 Myeloid cell surface antigen CD33 6540 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778483&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292920 523296830 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560901 Cc1cc2cc(C)c1OCCCNC(=O)CCCCCCC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C39H58N6O10/c1-24-18-27-19-25(2)35(24)54-17-11-16-40-31(48)14-9-4-3-5-10-15-39(38(52)53)20-29(46)33(36(55-39)34(50)30(47)21-41-37(27)51)42-32(49)23-45-22-28(43-44-45)26-12-7-6-8-13-26/h18-19,22,26,29-30,33-34,36,46-47,50H,3-17,20-21,23H2,1-2H3,(H,40,48)(H,41,51)(H,42,49)(H,52,53) SDVOYHOZMWURBM-UHFFFAOYSA-N 778484 US20250313574, Example A-344 Myeloid cell surface antigen CD33 18000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778484 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778484&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292777 523296831 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560902 Cc1cc2cc(C)c1OCCCNC(=O)CCCCCC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C38H56N6O10/c1-23-17-26-18-24(2)34(23)53-16-10-15-39-30(47)13-8-3-4-9-14-38(37(51)52)19-28(45)32(35(54-38)33(49)29(46)20-40-36(26)50)41-31(48)22-44-21-27(42-43-44)25-11-6-5-7-12-25/h17-18,21,25,28-29,32-33,35,45-46,49H,3-16,19-20,22H2,1-2H3,(H,39,47)(H,40,50)(H,41,48)(H,51,52) UEXVLGQDCWMPBK-UHFFFAOYSA-N 778485 US20250313574, Example A-345 Myeloid cell surface antigen CD33 21370 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778485 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778485&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893504 523296832 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560903 Cc1cc2cc(C)c1OCCCCNC(=O)CCCCCC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C39H58N6O10/c1-24-18-27-19-25(2)35(24)54-17-11-10-16-40-31(48)14-8-3-4-9-15-39(38(52)53)20-29(46)33(36(55-39)34(50)30(47)21-41-37(27)51)42-32(49)23-45-22-28(43-44-45)26-12-6-5-7-13-26/h18-19,22,26,29-30,33-34,36,46-47,50H,3-17,20-21,23H2,1-2H3,(H,40,48)(H,41,51)(H,42,49)(H,52,53) MBJPTNWFWUOGPW-UHFFFAOYSA-N 778486 US20250313574, Example A-346 Myeloid cell surface antigen CD33 13310 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778486 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778486&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292756 523296833 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560904 Cc1cc2cc(C)c1OCCNC(=O)CCCCCCCC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C39H58N6O10/c1-24-18-27-19-25(2)35(24)54-17-16-40-31(48)14-10-5-3-4-6-11-15-39(38(52)53)20-29(46)33(36(55-39)34(50)30(47)21-41-37(27)51)42-32(49)23-45-22-28(43-44-45)26-12-8-7-9-13-26/h18-19,22,26,29-30,33-34,36,46-47,50H,3-17,20-21,23H2,1-2H3,(H,40,48)(H,41,51)(H,42,49)(H,52,53) AFPOWBQEHVEECV-UHFFFAOYSA-N 778487 US20250313574, Example A-347 Myeloid cell surface antigen CD33 18970 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778487&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292958 523296834 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560905 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/c3cccc(c3)[C@@H](NC(=O)[C@H]3CCCOC3)CCCCOc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C40H53N3O11/c1-23-17-29-18-24(2)35(23)53-16-5-4-13-30(43-38(49)28-12-8-15-52-22-28)27-11-6-9-26(19-27)10-7-14-40(39(50)51)20-31(45)33(42-25(3)44)36(54-40)34(47)32(46)21-41-37(29)48/h6-7,9-11,17-19,28,30-34,36,45-47H,4-5,8,12-16,20-22H2,1-3H3,(H,41,48)(H,42,44)(H,43,49)(H,50,51) ZOPPACQZITUXKU-UHFFFAOYSA-N 778488 US20250313574, Example A-348 Myeloid cell surface antigen CD33 10100 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778488 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778488&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292873 523296835 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560906 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/c3cccc(c3)[C@@H](NC(=O)[C@@H]3CCCOC3)CCCCOc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C40H53N3O11/c1-23-17-29-18-24(2)35(23)53-16-5-4-13-30(43-38(49)28-12-8-15-52-22-28)27-11-6-9-26(19-27)10-7-14-40(39(50)51)20-31(45)33(42-25(3)44)36(54-40)34(47)32(46)21-41-37(29)48/h6-7,9-11,17-19,28,30-34,36,45-47H,4-5,8,12-16,20-22H2,1-3H3,(H,41,48)(H,42,44)(H,43,49)(H,50,51) ZOPPACQZITUXKU-UHFFFAOYSA-N 778489 US20250313574, Example A-349 Myeloid cell surface antigen CD33 5240 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778489 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778489&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893505 523296836 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560907 Cc1cc2cc(C)c1OCCCC[C@H](NC(=O)C1CCCOC1)c1cccc(c1)/C=C/C[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C48H64N6O11/c1-29-21-35-22-30(2)43(29)64-20-7-6-17-36(50-46(60)34-16-10-19-63-28-34)33-15-8-11-31(23-33)12-9-18-48(47(61)62)24-38(55)41(44(65-48)42(58)39(56)25-49-45(35)59)51-40(57)27-54-26-37(52-53-54)32-13-4-3-5-14-32/h8-9,11-12,15,21-23,26,32,34,36,38-39,41-42,44,55-56,58H,3-7,10,13-14,16-20,24-25,27-28H2,1-2H3,(H,49,59)(H,50,60)(H,51,57)(H,61,62) VEDVZTBEQJICGG-UHFFFAOYSA-N 778490 US20250313574, Example A-350 Myeloid cell surface antigen CD33 13270 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778490 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778490&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292831 523296837 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560908 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(CCCc3cccc(c3)[C@@H](NC(=O)C3CCCOC3)CCCCc3cc(cc(Cl)c3O)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C38H50ClN3O11/c1-21(43)41-31-29(44)18-38(37(50)51)13-5-8-22-7-4-10-23(15-22)28(42-36(49)25-11-6-14-52-20-25)12-3-2-9-24-16-26(17-27(39)32(24)46)35(48)40-19-30(45)33(47)34(31)53-38/h4,7,10,15-17,25,28-31,33-34,44-47H,2-3,5-6,8-9,11-14,18-20H2,1H3,(H,40,48)(H,41,43)(H,42,49)(H,50,51) YAHDONXHDKMABI-UHFFFAOYSA-N 778491 US20250313574, Example A-351 Myeloid cell surface antigen CD33 14990 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778491 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778491&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893506 523296838 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560909 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/c3cccc(c3)[C@@H](NC(=O)C3CCCOC3)CCCc3cc(cc(Cl)c3O)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C37H46ClN3O11/c1-20(42)40-30-28(43)17-37(36(49)50)12-4-7-21-6-2-8-22(14-21)27(41-35(48)24-10-5-13-51-19-24)11-3-9-23-15-25(16-26(38)31(23)45)34(47)39-18-29(44)32(46)33(30)52-37/h2,4,6-8,14-16,24,27-30,32-33,43-46H,3,5,9-13,17-19H2,1H3,(H,39,47)(H,40,42)(H,41,48)(H,49,50) JUMAELVODFNMKJ-UHFFFAOYSA-N 778492 US20250313574, Example A-352 Myeloid cell surface antigen CD33 94000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778492&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292880 523296839 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560910 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/c3cccc(c3)[C@@H](NC(=O)C3CCCOC3)CCCCc3cc(cc(Cl)c3O)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C38H48ClN3O11/c1-21(43)41-31-29(44)18-38(37(50)51)13-5-8-22-7-4-10-23(15-22)28(42-36(49)25-11-6-14-52-20-25)12-3-2-9-24-16-26(17-27(39)32(24)46)35(48)40-19-30(45)33(47)34(31)53-38/h4-5,7-8,10,15-17,25,28-31,33-34,44-47H,2-3,6,9,11-14,18-20H2,1H3,(H,40,48)(H,41,43)(H,42,49)(H,50,51) TWEWMQBEVJBAPS-UHFFFAOYSA-N 778493 US20250313574, Example A-353 Myeloid cell surface antigen CD33 18970 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778493 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778493&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292758 523296840 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560911 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/CCC[C@@H](NC(=O)[C@@H]3CCCOC3)c3cccc(c3)COc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C40H53N3O11/c1-23-16-29-17-24(2)35(23)53-21-26-10-8-11-27(18-26)30(43-38(49)28-12-9-15-52-22-28)13-6-4-5-7-14-40(39(50)51)19-31(45)33(42-25(3)44)36(54-40)34(47)32(46)20-41-37(29)48/h5,7-8,10-11,16-18,28,30-34,36,45-47H,4,6,9,12-15,19-22H2,1-3H3,(H,41,48)(H,42,44)(H,43,49)(H,50,51) KIPQBUBBNYLCCJ-UHFFFAOYSA-N 778494 US20250313574, Example A-354 Myeloid cell surface antigen CD33 27500 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778494 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778494&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292764 523296841 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560912 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(C/C=C/CCC[C@@H](NC(=O)[C@H]3CCCOC3)c3cccc(c3)COc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C40H53N3O11/c1-23-16-29-17-24(2)35(23)53-21-26-10-8-11-27(18-26)30(43-38(49)28-12-9-15-52-22-28)13-6-4-5-7-14-40(39(50)51)19-31(45)33(42-25(3)44)36(54-40)34(47)32(46)20-41-37(29)48/h5,7-8,10-11,16-18,28,30-34,36,45-47H,4,6,9,12-15,19-22H2,1-3H3,(H,41,48)(H,42,44)(H,43,49)(H,50,51) KIPQBUBBNYLCCJ-UHFFFAOYSA-N 778495 US20250313574, Example A-355 Myeloid cell surface antigen CD33 35400 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778495 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778495&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292817 523296842 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560913 Cc1cc2cc(C)c1OCc1cccc(c1)[C@H](NC(=O)C1CCCOC1)CCC/C=C/C[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C48H64N6O11/c1-29-20-35-21-30(2)43(29)64-27-31-12-10-15-33(22-31)36(50-46(60)34-16-11-19-63-28-34)17-8-3-4-9-18-48(47(61)62)23-38(55)41(44(65-48)42(58)39(56)24-49-45(35)59)51-40(57)26-54-25-37(52-53-54)32-13-6-5-7-14-32/h4,9-10,12,15,20-22,25,32,34,36,38-39,41-42,44,55-56,58H,3,5-8,11,13-14,16-19,23-24,26-28H2,1-2H3,(H,49,59)(H,50,60)(H,51,57)(H,61,62) BNRDRHHWXMTOIR-UHFFFAOYSA-N 778496 US20250313574, Example A-356 Myeloid cell surface antigen CD33 1510 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778496 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778496&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292926 523296843 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560914 CC(=O)N[C@H]1[C@H]2O[C@](C(=O)O)(CC/C=C/CO[C@H]3C[C@H](CN3C(=O)C3CCCOC3)OCCOc3c(C)cc(cc3C)C(=O)NC[C@@H](O)[C@H]2O)C[C@@H]1O InChI=1S/C37H53N3O13/c1-21-14-25-15-22(2)32(21)52-13-12-50-26-16-29(40(19-26)35(46)24-8-7-10-49-20-24)51-11-6-4-5-9-37(36(47)48)17-27(42)30(39-23(3)41)33(53-37)31(44)28(43)18-38-34(25)45/h4,6,14-15,24,26-31,33,42-44H,5,7-13,16-20H2,1-3H3,(H,38,45)(H,39,41)(H,47,48) FIDKJZFRTIUXQM-UHFFFAOYSA-N 778497 US20250313574, Example A-357 Myeloid cell surface antigen CD33 66100 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778497 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778497&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292759 523296844 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560915 Cc1cc2cc(C)c1OCCO[C@@H]1C[C@H](OC/C=C/CC[C@]3(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn4cc(C5CCCCC5)nn4)[C@@H](O3)[C@H](O)[C@H](O)CNC2=O)N(C(=O)C2CCCOC2)C1 InChI=1S/C45H64N6O13/c1-27-18-31-19-28(2)40(27)63-17-16-61-32-20-37(51(23-32)43(57)30-12-9-14-60-26-30)62-15-8-4-7-13-45(44(58)59)21-34(52)38(41(64-45)39(55)35(53)22-46-42(31)56)47-36(54)25-50-24-33(48-49-50)29-10-5-3-6-11-29/h4,8,18-19,24,29-30,32,34-35,37-39,41,52-53,55H,3,5-7,9-17,20-23,25-26H2,1-2H3,(H,46,56)(H,47,54)(H,58,59) RYERTJKXKKLSDO-UHFFFAOYSA-N 778498 US20250313574, Example A-358 Myeloid cell surface antigen CD33 9430 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778498 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778498&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292738 523296845 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560916 Cc1cc2cc(C)c1OCCCNC(=O)[C@H](C)COCCCC[C@]1(C(=O)O)C[C@H](O)[C@@H](NC(=O)Cn3cc(C4CCCCC4)nn3)[C@@H](O1)[C@H](O)[C@H](O)CNC2=O InChI=1S/C39H58N6O11/c1-23-16-27-17-24(2)34(23)55-15-9-13-40-36(50)25(3)22-54-14-8-7-12-39(38(52)53)18-29(46)32(35(56-39)33(49)30(47)19-41-37(27)51)42-31(48)21-45-20-28(43-44-45)26-10-5-4-6-11-26/h16-17,20,25-26,29-30,32-33,35,46-47,49H,4-15,18-19,21-22H2,1-3H3,(H,40,50)(H,41,51)(H,42,48)(H,52,53) PQHARSDHMFAGQK-UHFFFAOYSA-N 778499 US20250313574, Example A-359 Myeloid cell surface antigen CD33 59800 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778499 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778499&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292739 523296846 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560917 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@](CO)(CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)C[C@@H]1O InChI=1S/C34H54N4O11/c1-20-13-23(14-21(2)27(20)43)30(45)35-16-25(42)28(44)29-26(36-22(3)40)24(41)15-34(18-39,48-29)8-10-38-11-12-47-19-33(38)7-9-37(17-33)31(46)49-32(4,5)6/h13-14,24-26,28-29,39,41-44H,7-12,15-19H2,1-6H3,(H,35,45)(H,36,40) TYLAIEWLAPDHKG-UHFFFAOYSA-N 778500 US20250313574, Example A-360 Myeloid cell surface antigen CD33 >100000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778500 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778500&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893507 523296847 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560918 COC(=O)[C@@]1(CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O1 InChI=1S/C35H54N4O12/c1-20-14-23(15-21(2)27(20)43)30(45)36-17-25(42)28(44)29-26(37-22(3)40)24(41)16-35(50-29,31(46)48-7)9-11-39-12-13-49-19-34(39)8-10-38(18-34)32(47)51-33(4,5)6/h14-15,24-26,28-29,41-44H,8-13,16-19H2,1-7H3,(H,36,45)(H,37,40) ZYUMIDKGBSMBRA-UHFFFAOYSA-N 778501 US20250313574, Example A-361 Myeloid cell surface antigen CD33 49000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778501 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778501&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177292754 523296848 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560919 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(c2nn[nH]n2)C[C@@H]1O InChI=1S/C34H52N8O10/c1-19-13-22(14-20(2)26(19)46)29(48)35-16-24(45)27(47)28-25(36-21(3)43)23(44)15-34(51-28,30-37-39-40-38-30)8-10-42-11-12-50-18-33(42)7-9-41(17-33)31(49)52-32(4,5)6/h13-14,23-25,27-28,44-47H,7-12,15-18H2,1-6H3,(H,35,48)(H,36,43)(H,37,38,39,40) XQUBLXOOHPADAN-UHFFFAOYSA-N 778502 US20250313574, Example A-363 Myeloid cell surface antigen CD33 6360 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778502 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778502&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893508 523296849 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560920 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@](C#N)(CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)C[C@@H]1O InChI=1S/C34H51N5O10/c1-20-13-23(14-21(2)27(20)43)30(45)36-16-25(42)28(44)29-26(37-22(3)40)24(41)15-34(17-35,48-29)8-10-39-11-12-47-19-33(39)7-9-38(18-33)31(46)49-32(4,5)6/h13-14,24-26,28-29,41-44H,7-12,15-16,18-19H2,1-6H3,(H,36,45)(H,37,40) ZSQAHFDMCQXYSX-UHFFFAOYSA-N 778503 US20250313574, Example A-362 Myeloid cell surface antigen CD33 >100000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778503 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778503&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893509 523296850 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560921 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(N)=O)C[C@@H]1O InChI=1S/C34H53N5O11/c1-19-13-22(14-20(2)26(19)43)29(45)36-16-24(42)27(44)28-25(37-21(3)40)23(41)15-34(49-28,30(35)46)8-10-39-11-12-48-18-33(39)7-9-38(17-33)31(47)50-32(4,5)6/h13-14,23-25,27-28,41-44H,7-12,15-18H2,1-6H3,(H2,35,46)(H,36,45)(H,37,40) KMGVKCQALAMUTR-UHFFFAOYSA-N 778504 US20250313574, Example A-364 Myeloid cell surface antigen CD33 >100000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778504 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778504&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893510 523296851 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560922 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)NS(C)(=O)=O)C[C@@H]1O InChI=1S/C35H55N5O13S/c1-20-14-23(15-21(2)27(20)44)30(46)36-17-25(43)28(45)29-26(37-22(3)41)24(42)16-35(52-29,31(47)38-54(7,49)50)9-11-40-12-13-51-19-34(40)8-10-39(18-34)32(48)53-33(4,5)6/h14-15,24-26,28-29,42-45H,8-13,16-19H2,1-7H3,(H,36,46)(H,37,41)(H,38,47) XRBVRSVUPSJVKD-UHFFFAOYSA-N 778505 US20250313574, Example A-365 Myeloid cell surface antigen CD33 37500 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778505 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778505&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893511 523296852 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560923 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)NC#N)C[C@@H]1O InChI=1S/C35H52N6O11/c1-20-13-23(14-21(2)27(20)45)30(47)37-16-25(44)28(46)29-26(39-22(3)42)24(43)15-35(51-29,31(48)38-19-36)8-10-41-11-12-50-18-34(41)7-9-40(17-34)32(49)52-33(4,5)6/h13-14,24-26,28-29,43-46H,7-12,15-18H2,1-6H3,(H,37,47)(H,38,48)(H,39,42) DXAITGWALOFNRE-UHFFFAOYSA-N 778506 US20250313574, Example A-366 Myeloid cell surface antigen CD33 2830 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778506 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778506&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893512 523296853 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560924 CC(=O)NC1C(O)CC(CCN2CCOCC23CCN(C(=O)OC(C)(C)C)C3)(C(=O)NS(=O)(=O)C(F)(F)F)OC1C(O)C(O)CNC(=O)c1cc(C)c(O)c(C)c1 InChI=1S/C35H52F3N5O13S/c1-19-13-22(14-20(2)26(19)47)29(49)39-16-24(46)27(48)28-25(40-21(3)44)23(45)15-34(55-28,30(50)41-57(52,53)35(36,37)38)8-10-43-11-12-54-18-33(43)7-9-42(17-33)31(51)56-32(4,5)6/h13-14,23-25,27-28,45-48H,7-12,15-18H2,1-6H3,(H,39,49)(H,40,44)(H,41,50) NVINCDMSCWGNIT-UHFFFAOYSA-N 778507 US20250313574, Example A-367 Myeloid cell surface antigen CD33 >100000 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778507 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778507&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893513 523296854 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24 1560925 CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CNC(=O)c2cc(C)c(O)c(C)c2)O[C@@](CCN2CCOC[C@@]23CCN(C(=O)OC(C)(C)C)C3)(C(=O)NS(=O)(=O)c2ccccc2)C[C@@H]1O InChI=1S/C40H57N5O13S/c1-24-18-27(19-25(2)32(24)49)35(51)41-21-30(48)33(50)34-31(42-26(3)46)29(47)20-40(57-34,36(52)43-59(54,55)28-10-8-7-9-11-28)13-15-45-16-17-56-23-39(45)12-14-44(22-39)37(53)58-38(4,5)6/h7-11,18-19,29-31,33-34,47-50H,12-17,20-23H2,1-6H3,(H,41,51)(H,42,46)(H,43,52) JECDKDYVGWTTEH-UHFFFAOYSA-N 778508 US20250313574, Example A-368 Myeloid cell surface antigen CD33 14960 US Patent 10.7270/Q29Z99P5 US20250313574 HAWKINS, LD; MITASEV, B; CHASE, C; LEE, J; LEE, JH; LI, D; SCHNADERBECK, M; SHAN, MD; YU, RT; ZHENG, W; ZHU, X; ARAI, J; FANG, FG; WANG, J 10/9/2025 1/29/2026 Eisai R&D Management Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=778508 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2055&target=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=778508&enzyme=Myeloid+cell+surface+antigen+CD33&column=ki&startPg=0&Increment=50&submit=Search 177893514 523296855 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 7AW6,6D4A,6D49,6D48,9BET Myeloid cell surface antigen CD33 CD33_HUMAN P20138 B4E3P8 C9JEN7 F8WAL2 Q8TD24