BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 198958 Fc1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 InChI=1S/C23H17FN4O/c24-18-9-5-16(6-10-18)22(28-14-13-25-15-28)17-7-11-19(12-8-17)26-23-27-20-3-1-2-4-21(20)29-23/h1-15,22H,(H,26,27) BWXLOGGHGYONLD-UHFFFAOYSA-N 91698 Oxazolamine derivative, 5a Cytochrome P450 26A1 Homo sapiens 3.5e+4 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91698&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 57412004 136959485 ZINC89469053 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198959 Cc1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 InChI=1S/C24H20N4O/c1-17-6-8-18(9-7-17)23(28-15-14-25-16-28)19-10-12-20(13-11-19)26-24-27-21-4-2-3-5-22(21)29-24/h2-16,23H,1H3,(H,26,27) SVQZVWJCVISARJ-UHFFFAOYSA-N 91699 Oxazolamine derivative, 5b Cytochrome P450 26A1 Homo sapiens 9e+3 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91699&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44123836 136959486 ZINC87612856 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198960 COC(=O)c1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 InChI=1S/C25H20N4O3/c1-31-24(30)19-8-6-17(7-9-19)23(29-15-14-26-16-29)18-10-12-20(13-11-18)27-25-28-21-4-2-3-5-22(21)32-25/h2-16,23H,1H3,(H,27,28) XBGHZEQQURGHPO-UHFFFAOYSA-N 91700 Oxazolamine derivative, 5c Cytochrome P450 26A1 Homo sapiens 2.0e+4 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91700&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 57412005 136959487 ZINC89469058 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198961 OC(=O)c1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 InChI=1S/C24H18N4O3/c29-23(30)18-7-5-16(6-8-18)22(28-14-13-25-15-28)17-9-11-19(12-10-17)26-24-27-20-3-1-2-4-21(20)31-24/h1-15,22H,(H,26,27)(H,29,30) MPCTUARKBAIYDX-UHFFFAOYSA-N 91701 Oxazolamine derivative, 5d Cytochrome P450 26A1 Homo sapiens 5.0e+4 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91701&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 57412006 136959488 ZINC87612858 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198962 COc1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 InChI=1S/C24H20N4O2/c1-29-20-12-8-18(9-13-20)23(28-15-14-25-16-28)17-6-10-19(11-7-17)26-24-27-21-4-2-3-5-22(21)30-24/h2-16,23H,1H3,(H,26,27) MIRZPMYXEXSLFC-UHFFFAOYSA-N 91702 Oxazolamine derivative, 5e Cytochrome P450 26A1 Homo sapiens >2.0e+4 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91702&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 57412007 136959489 ZINC89469064 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198963 Oc1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 InChI=1S/C23H18N4O2/c28-19-11-7-17(8-12-19)22(27-14-13-24-15-27)16-5-9-18(10-6-16)25-23-26-20-3-1-2-4-21(20)29-23/h1-15,22,28H,(H,25,26) RANAONQXHNMZQO-UHFFFAOYSA-N 91703 Oxazolamine derivative, 5f Cytochrome P450 26A1 Homo sapiens 1.2e+4 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91703&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44123837 136959490 ZINC87612860 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198964 Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50176808 5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benzoimidazole::6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL389433::US9138393, Liarizole hydrochloride::US9144538, Liarizole hydrochloride::liarozole Cytochrome P450 26A1 Homo sapiens 7e+3 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176808&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 104062424 CHEMBL389433 5210 ZINC11687637 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198965 CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25) SNFYYXUGUBUECJ-UHFFFAOYSA-N 50253810 CHEMBL459505::N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)benzo[d]thiazol-2-amine::R-115866::R115866::US9963439, Talarozole Cytochrome P450 26A1 Homo sapiens 5 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253810&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9799888 104106249 CHEMBL459505 ZINC13675264 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198966 N(c1nc2ccccc2o1)c1ccc(cc1)C(c1ccccc1)n1cncn1 InChI=1S/C22H17N5O/c1-2-6-16(7-3-1)21(27-15-23-14-24-27)17-10-12-18(13-11-17)25-22-26-19-8-4-5-9-20(19)28-22/h1-15,21H,(H,25,26) UCUUEYSGSMOFHP-UHFFFAOYSA-N 91704 1H-1,2,4-triazole, 11 Cytochrome P450 26A1 Homo sapiens 1.8e+4 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91704&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 57412008 136959491 ZINC89469068 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198967 N(c1nc2ccccc2o1)c1ccc(cc1)C(c1ccccc1)n1cnnc1 InChI=1S/C22H17N5O/c1-2-6-16(7-3-1)21(27-14-23-24-15-27)17-10-12-18(13-11-17)25-22-26-19-8-4-5-9-20(19)28-22/h1-15,21H,(H,25,26) ARWCHMOSESFXRO-UHFFFAOYSA-N 91705 1H-1,2,4-triazole, 12 Cytochrome P450 26A1 Homo sapiens >2.0e+4 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91705&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 57412009 136959492 ZINC87612862 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 198968 N(c1nc2ccccc2o1)c1ccc(cc1)C(c1ccccc1)n1cnnn1 InChI=1S/C21H16N6O/c1-2-6-15(7-3-1)20(27-14-22-25-26-27)16-10-12-17(13-11-16)23-21-24-18-8-4-5-9-19(18)28-21/h1-14,20H,(H,23,24) KSUVCDUWHNGSDW-UHFFFAOYSA-N 91706 1H-tetrazole, 13 Cytochrome P450 26A1 Homo sapiens >2.0e+4 Curated from the literature by BindingDB 10.1080/14756360802218334 10.7270/Q2CR5RZ5 18608743 aid1799732 Pautus, S; Aboraia, AS; Bassett, CE; Brancale, A; Coogan, MP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91706&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 57412010 136959493 ZINC89469072 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290782 C\C(\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1)=C/C=C/C(/C)=C/C(=O)n1ccnc1 InChI=1S/C26H32N4O/c1-20(7-6-8-21(2)17-25(31)30-16-14-28-19-30)9-10-23-22(3)24(11-12-26(23,4)5)29-15-13-27-18-29/h6-10,13-19,24H,11-12H2,1-5H3/b8-6+,10-9+,20-7+,21-17+ YATHTDAMJIBVQL-NOTPUAICSA-N 50158410 4-((+/-)-(1H-imidazol-1-yl)-N-(imidazolyl)-(E)-retinamide::CHEMBL223072 Cytochrome P450 26A1 Homo sapiens 10 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158410&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11373414 104045164 CHEMBL223072 ZINC13586650 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290783 C\C(\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1 InChI=1S/C29H35N3O2/c1-21(7-6-8-22(2)19-28(34)31-24-10-12-25(33)13-11-24)9-14-26-23(3)27(15-16-29(26,4)5)32-18-17-30-20-32/h6-14,17-20,27,33H,15-16H2,1-5H3,(H,31,34)/b8-6+,14-9+,21-7+,22-19+ JHEWGPADVYIQFU-LBTWASEZSA-N 50158411 (2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-cyclohex-1-enyl)-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide::4-((+/-)-(1H-imidazol-1-yl)-N-(4-hydroxyphenyl)-(E)-retinamide::9-(3-(1H-imidazol-1-yl)-2,6,6-trimethylcyclohex-1-enyl)-N-(4-hydroxyphenyl)-3,7-dimethylnona-2,4,6,8-tetraenamide::CHEMBL190837 Cytochrome P450 26A1 Homo sapiens 56 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158411&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11236452 104045165 CHEMBL190837 ZINC13586652 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290787 COC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)[C@@H](CCC1(C)C)n1ccnc1 InChI=1S/C24H32N2O2/c1-18(8-7-9-19(2)16-23(27)28-6)10-11-21-20(3)22(12-13-24(21,4)5)26-15-14-25-17-26/h7-11,14-17,22H,12-13H2,1-6H3/b9-7+,11-10+,18-8+,19-16+/t22-/m1/s1 LEOKNFOQHCUMCU-SRXKHEPPSA-N 50158414 (R,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethylnona-2,4,6,8-tetraenoate::(S,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethylnona-2,4,6,8-tetraenoate::CHEMBL225621 Cytochrome P450 26A1 Homo sapiens 6000 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158414&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44421467 104045168 CHEMBL225621 ZINC06716099 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290788 COC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1 InChI=1S/C24H32N2O2/c1-18(8-7-9-19(2)16-23(27)28-6)10-11-21-20(3)22(12-13-24(21,4)5)26-15-14-25-17-26/h7-11,14-17,22H,12-13H2,1-6H3/b9-7+,11-10+,18-8+,19-16+ LEOKNFOQHCUMCU-PFLBVIONSA-N 50158415 4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate::CHEMBL224828 Cytochrome P450 26A1 Homo sapiens 40 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158415&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 10786043 104045169 CHEMBL224828 ZINC11687481 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290793 C\C(\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1)=C/C=C/C(/C)=C/C(=O)n1ccnc1 InChI=1S/C26H32N4O/c1-20(7-6-8-21(2)17-25(31)30-16-14-28-19-30)9-10-23-22(3)24(11-12-26(23,4)5)29-15-13-27-18-29/h6-10,13-19,24H,11-12H2,1-5H3/b8-6+,10-9+,20-7+,21-17+ YATHTDAMJIBVQL-NOTPUAICSA-N 50158410 4-((+/-)-(1H-imidazol-1-yl)-N-(imidazolyl)-(E)-retinamide::CHEMBL223072 Cytochrome P450 26A1 Homo sapiens 5.2 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158410&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11373414 104045164 CHEMBL223072 ZINC13586650 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290797 C\C(\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1)=C/C=C/C(/C)=C/C(=O)n1ccnc1 InChI=1S/C26H32N4O/c1-20(7-6-8-21(2)17-25(31)30-16-14-28-19-30)9-10-23-22(3)24(11-12-26(23,4)5)29-15-13-27-18-29/h6-10,13-19,24H,11-12H2,1-5H3/b8-6+,10-9+,20-7+,21-17+ YATHTDAMJIBVQL-NOTPUAICSA-N 50158410 4-((+/-)-(1H-imidazol-1-yl)-N-(imidazolyl)-(E)-retinamide::CHEMBL223072 Cytochrome P450 26A1 Homo sapiens 24.7 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158410&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11373414 104045164 CHEMBL223072 ZINC13586650 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290798 COC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1 InChI=1S/C24H32N2O2/c1-18(8-7-9-19(2)16-23(27)28-6)10-11-21-20(3)22(12-13-24(21,4)5)26-15-14-25-17-26/h7-11,14-17,22H,12-13H2,1-6H3/b9-7+,11-10+,18-8+,19-16+ LEOKNFOQHCUMCU-PFLBVIONSA-N 50158415 4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate::CHEMBL224828 Cytochrome P450 26A1 Homo sapiens 200 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158415&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 10786043 104045169 CHEMBL224828 ZINC11687481 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290799 C\C(\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1)=C/C=C/C(/C)=C/C(O)=O InChI=1S/C23H30N2O2/c1-17(7-6-8-18(2)15-22(26)27)9-10-20-19(3)21(11-12-23(20,4)5)25-14-13-24-16-25/h6-10,13-16,21H,11-12H2,1-5H3,(H,26,27)/b8-6+,10-9+,17-7+,18-15+ MRFBVQCSZMKBFY-UBFIAYEVSA-N 50091698 (2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-cyclohex-1-enyl)-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid::4-((+/-)-(1H-imidazol-1-yl)-(E)-retinoic acid::CHEMBL57765 Cytochrome P450 26A1 Homo sapiens 10.9 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091698&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9951075 103989929 CHEMBL57765 ZINC40434388 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290800 C\C(\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1)=C/C=C/C(/C)=C/C(O)=O InChI=1S/C23H30N2O2/c1-17(7-6-8-18(2)15-22(26)27)9-10-20-19(3)21(11-12-23(20,4)5)25-14-13-24-16-25/h6-10,13-16,21H,11-12H2,1-5H3,(H,26,27)/b8-6+,10-9+,17-7+,18-15+ MRFBVQCSZMKBFY-UBFIAYEVSA-N 50091698 (2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-cyclohex-1-enyl)-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid::4-((+/-)-(1H-imidazol-1-yl)-(E)-retinoic acid::CHEMBL57765 Cytochrome P450 26A1 Homo sapiens 6.3 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091698&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9951075 103989929 CHEMBL57765 ZINC40434388 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290801 C\C(\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1)=C/C=C/C(/C)=C/C(O)=O InChI=1S/C23H30N2O2/c1-17(7-6-8-18(2)15-22(26)27)9-10-20-19(3)21(11-12-23(20,4)5)25-14-13-24-16-25/h6-10,13-16,21H,11-12H2,1-5H3,(H,26,27)/b8-6+,10-9+,17-7+,18-15+ MRFBVQCSZMKBFY-UBFIAYEVSA-N 50091698 (2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-cyclohex-1-enyl)-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid::4-((+/-)-(1H-imidazol-1-yl)-(E)-retinoic acid::CHEMBL57765 Cytochrome P450 26A1 Homo sapiens 2.4 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091698&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9951075 103989929 CHEMBL57765 ZINC40434388 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290803 C\C(\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1 InChI=1S/C29H35N3O2/c1-21(7-6-8-22(2)19-28(34)31-24-10-12-25(33)13-11-24)9-14-26-23(3)27(15-16-29(26,4)5)32-18-17-30-20-32/h6-14,17-20,27,33H,15-16H2,1-5H3,(H,31,34)/b8-6+,14-9+,21-7+,22-19+ JHEWGPADVYIQFU-LBTWASEZSA-N 50158411 (2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-cyclohex-1-enyl)-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide::4-((+/-)-(1H-imidazol-1-yl)-N-(4-hydroxyphenyl)-(E)-retinamide::9-(3-(1H-imidazol-1-yl)-2,6,6-trimethylcyclohex-1-enyl)-N-(4-hydroxyphenyl)-3,7-dimethylnona-2,4,6,8-tetraenamide::CHEMBL190837 Cytochrome P450 26A1 Homo sapiens 24 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158411&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11236452 104045165 CHEMBL190837 ZINC13586652 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290808 COC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(CCC1(C)C)n1ccnc1 InChI=1S/C24H32N2O2/c1-18(8-7-9-19(2)16-23(27)28-6)10-11-21-20(3)22(12-13-24(21,4)5)26-15-14-25-17-26/h7-11,14-17,22H,12-13H2,1-6H3/b9-7+,11-10+,18-8+,19-16+ LEOKNFOQHCUMCU-PFLBVIONSA-N 50158415 4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate::CHEMBL224828 Cytochrome P450 26A1 Homo sapiens 215 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158415&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 10786043 104045169 CHEMBL224828 ZINC11687481 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290809 COC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)[C@@H](CCC1(C)C)n1ccnc1 InChI=1S/C24H32N2O2/c1-18(8-7-9-19(2)16-23(27)28-6)10-11-21-20(3)22(12-13-24(21,4)5)26-15-14-25-17-26/h7-11,14-17,22H,12-13H2,1-6H3/b9-7+,11-10+,18-8+,19-16+/t22-/m1/s1 LEOKNFOQHCUMCU-SRXKHEPPSA-N 50158414 (R,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethylnona-2,4,6,8-tetraenoate::(S,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethylnona-2,4,6,8-tetraenoate::CHEMBL225621 Cytochrome P450 26A1 Homo sapiens 800 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158414&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44421467 104045168 CHEMBL225621 ZINC06716099 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50290810 COC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)[C@@H](CCC1(C)C)n1ccnc1 InChI=1S/C24H32N2O2/c1-18(8-7-9-19(2)16-23(27)28-6)10-11-21-20(3)22(12-13-24(21,4)5)26-15-14-25-17-26/h7-11,14-17,22H,12-13H2,1-6H3/b9-7+,11-10+,18-8+,19-16+/t22-/m1/s1 LEOKNFOQHCUMCU-SRXKHEPPSA-N 50158414 (R,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethylnona-2,4,6,8-tetraenoate::(S,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethylnona-2,4,6,8-tetraenoate::CHEMBL225621 Cytochrome P450 26A1 Homo sapiens 800 ChEMBL 10.1021/jm0401457 10.7270/Q2K64HJV 15615521 Patel, JB; Huynh, CK; Handratta, VD; Gediya, LK; Brodie, AM; Goloubeva, OG; Clement, OO; Nanne, IP; Soprano, DR; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158414&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44421467 104045168 CHEMBL225621 ZINC06716099 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300111 CC(C(c1ccc2cc(OCc3cccc(c3)C(=O)N(C)C)ccc2c1)n1ccnc1)N(C)C InChI=1S/C28H32N4O2/c1-20(30(2)3)27(32-14-13-29-19-32)24-10-9-23-17-26(12-11-22(23)16-24)34-18-21-7-6-8-25(15-21)28(33)31(4)5/h6-17,19-20,27H,18H2,1-5H3 WMGCLEIKLXKKON-UHFFFAOYSA-N 50162772 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-N,N-dimethyl-benzamide::CHEMBL360072 Cytochrome P450 26A1 Homo sapiens 14.4 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162772&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390142 104048887 CHEMBL360072 ZINC28336382 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300112 Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50176808 5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benzoimidazole::6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL389433::US9138393, Liarizole hydrochloride::US9144538, Liarizole hydrochloride::liarozole Cytochrome P450 26A1 Homo sapiens 6000 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176808&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 104062424 CHEMBL389433 5210 ZINC11687637 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300113 CC(C(c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C23H29N3O3/c1-16(25(4)5)21(26-11-10-24-15-26)19-7-6-18-13-20(9-8-17(18)12-19)29-14-23(2,3)22(27)28/h6-13,15-16,21H,14H2,1-5H3,(H,27,28) YLMRCYCGLCIPMC-UHFFFAOYSA-N 50162773 3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid::CHEMBL360771 Cytochrome P450 26A1 Homo sapiens 20 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162773&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11773824 104048888 CHEMBL360771 ZINC38363348 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300117 CC(C(c1ccc2cc(OCc3cccc(c3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C26H27N3O3/c1-18(28(2)3)25(29-12-11-27-17-29)22-8-7-21-15-24(10-9-20(21)14-22)32-16-19-5-4-6-23(13-19)26(30)31/h4-15,17-18,25H,16H2,1-3H3,(H,30,31) LUDUPPNOCMHNSY-UHFFFAOYSA-N 50162776 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid::CHEMBL426789 Cytochrome P450 26A1 Homo sapiens 3.50 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162776&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11235737 104048890 CHEMBL426789 ZINC28344228 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300121 CC(C(c1ccc2cc(OCc3ccc(CC(O)=O)cc3)ccc2c1)n1ccnc1)N(C)C InChI=1S/C27H29N3O3/c1-19(29(2)3)27(30-13-12-28-18-30)24-9-8-23-16-25(11-10-22(23)15-24)33-17-21-6-4-20(5-7-21)14-26(31)32/h4-13,15-16,18-19,27H,14,17H2,1-3H3,(H,31,32) ZCFKCDRXDKIAQV-UHFFFAOYSA-N 50162780 CHEMBL180348::{4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-phenyl}-acetic acid Cytochrome P450 26A1 Homo sapiens 25 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162780&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11154980 104048894 CHEMBL180348 C03768 ZINC28335784 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300122 CC(C(c1ccc2cc(OCC(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C20H23N3O3/c1-14(22(2)3)20(23-9-8-21-13-23)17-5-4-16-11-18(26-12-19(24)25)7-6-15(16)10-17/h4-11,13-14,20H,12H2,1-3H3,(H,24,25) HKJCSUNJDASSCM-UHFFFAOYSA-N 50162781 CHEMBL178873::[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-acetic acid Cytochrome P450 26A1 Homo sapiens 335 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162781&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390265 104048895 CHEMBL178873 ZINC28130169 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300123 CC(C(c1ccc2cc(OCc3ccc(OCC(O)=O)cc3)ccc2c1)n1ccnc1)N(C)C InChI=1S/C27H29N3O4/c1-19(29(2)3)27(30-13-12-28-18-30)23-7-6-22-15-25(11-8-21(22)14-23)33-16-20-4-9-24(10-5-20)34-17-26(31)32/h4-15,18-19,27H,16-17H2,1-3H3,(H,31,32) BZFNUUDZCGKAST-UHFFFAOYSA-N 50162782 CHEMBL179550::{4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-phenoxy}-acetic acid Cytochrome P450 26A1 Homo sapiens 8 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162782&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390231 104048896 CHEMBL179550 ZINC28128860 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300124 CC(C(c1ccc2cc(OCc3ccc(OC(C)(C)C)cc3)ccc2c1)n1ccnc1)N(C)C InChI=1S/C29H35N3O2/c1-21(31(5)6)28(32-16-15-30-20-32)25-10-9-24-18-27(14-11-23(24)17-25)33-19-22-7-12-26(13-8-22)34-29(2,3)4/h7-18,20-21,28H,19H2,1-6H3 ZYAKTISGGAZUDF-UHFFFAOYSA-N 50162784 CHEMBL181385::{2-[6-(4-tert-Butoxy-benzyloxy)-naphthalen-2-yl]-2-imidazol-1-yl-1-methyl-ethyl}-dimethyl-amine Cytochrome P450 26A1 Homo sapiens 34 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162784&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11590652 104048898 CHEMBL181385 ZINC28331853 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300128 CNC(=O)c1cccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)c1 InChI=1S/C27H30N4O2/c1-19(30(3)4)26(31-13-12-29-18-31)23-9-8-22-16-25(11-10-21(22)15-23)33-17-20-6-5-7-24(14-20)27(32)28-2/h5-16,18-19,26H,17H2,1-4H3,(H,28,32) YRZCYALYRQWTET-UHFFFAOYSA-N 50162785 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-N-methyl-benzamide::CHEMBL182438 Cytochrome P450 26A1 Homo sapiens 37 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162785&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390123 104048899 CHEMBL182438 ZINC28345011 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300129 CC(C(c1ccc2cc(OCc3ccc(OC(C)(C)C)cc3)ccc2c1)n1ccnc1)N(C)C InChI=1S/C29H35N3O2/c1-21(31(5)6)28(32-16-15-30-20-32)25-10-9-24-18-27(14-11-23(24)17-25)33-19-22-7-12-26(13-8-22)34-29(2,3)4/h7-18,20-21,28H,19H2,1-6H3 ZYAKTISGGAZUDF-UHFFFAOYSA-N 50162784 CHEMBL181385::{2-[6-(4-tert-Butoxy-benzyloxy)-naphthalen-2-yl]-2-imidazol-1-yl-1-methyl-ethyl}-dimethyl-amine Cytochrome P450 26A1 Homo sapiens 34.0 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162784&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11590652 104048898 CHEMBL181385 ZINC28331853 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300135 COC(=O)c1cccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)c1 InChI=1S/C27H29N3O3/c1-19(29(2)3)26(30-13-12-28-18-30)23-9-8-22-16-25(11-10-21(22)15-23)33-17-20-6-5-7-24(14-20)27(31)32-4/h5-16,18-19,26H,17H2,1-4H3 FHATZVOKYMKNGI-UHFFFAOYSA-N 50162788 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid methyl ester::CHEMBL181309 Cytochrome P450 26A1 Homo sapiens 7.00 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162788&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11510548 104048902 CHEMBL181309 ZINC28340102 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300137 COC(=O)COc1ccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)cc1 InChI=1S/C28H31N3O4/c1-20(30(2)3)28(31-14-13-29-19-31)24-8-7-23-16-26(12-9-22(23)15-24)34-17-21-5-10-25(11-6-21)35-18-27(32)33-4/h5-16,19-20,28H,17-18H2,1-4H3 VXPLIKXVYZZBFD-UHFFFAOYSA-N 50162778 CHEMBL362412::{4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-phenoxy}-acetic acid methyl ester Cytochrome P450 26A1 Homo sapiens 19.0 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162778&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390161 104048892 CHEMBL362412 ZINC28338371 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300140 CC(C(c1ccc2cc(OCc3ccc(cc3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C26H27N3O3/c1-18(28(2)3)25(29-13-12-27-17-29)23-9-8-22-15-24(11-10-21(22)14-23)32-16-19-4-6-20(7-5-19)26(30)31/h4-15,17-18,25H,16H2,1-3H3,(H,30,31) DMLUZARQJJUBAJ-UHFFFAOYSA-N 50162787 4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid::CHEMBL368448 Cytochrome P450 26A1 Homo sapiens 3.30 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162787&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11750760 104048901 CHEMBL368448 ZINC28335882 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300141 CC(C(c1ccc2cc(OCc3ccc(cc3)[N+]([O-])=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C25H26N4O3/c1-18(27(2)3)25(28-13-12-26-17-28)22-7-6-21-15-24(11-8-20(21)14-22)32-16-19-4-9-23(10-5-19)29(30)31/h4-15,17-18,25H,16H2,1-3H3 ATRBKKFCGWCOAE-UHFFFAOYSA-N 50162790 CHEMBL180592::{2-Imidazol-1-yl-1-methyl-2-[6-(4-nitro-benzyloxy)-naphthalen-2-yl]-ethyl}-dimethyl-amine Cytochrome P450 26A1 Homo sapiens 77 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162790&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11582790 104048904 CHEMBL180592 ZINC28345071 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300142 CC(C(c1ccc2cc(OCC(C)(C)C)ccc2c1)n1ccnc1)N(C)C InChI=1S/C23H31N3O/c1-17(25(5)6)22(26-12-11-24-16-26)20-8-7-19-14-21(10-9-18(19)13-20)27-15-23(2,3)4/h7-14,16-17,22H,15H2,1-6H3 ZZGVWUSRXVYCSC-UHFFFAOYSA-N 50162777 CHEMBL180805::{2-[6-(2,2-Dimethyl-propoxy)-naphthalen-2-yl]-2-imidazol-1-yl-1-methyl-ethyl}-dimethyl-amine Cytochrome P450 26A1 Homo sapiens 21.4 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162777&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11501485 104048891 CHEMBL180805 ZINC28344021 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300148 CC(C(c1ccc2cc(OCc3ccc(cc3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C26H27N3O3/c1-18(28(2)3)25(29-13-12-27-17-29)23-9-8-22-15-24(11-10-21(22)14-23)32-16-19-4-6-20(7-5-19)26(30)31/h4-15,17-18,25H,16H2,1-3H3,(H,30,31) DMLUZARQJJUBAJ-UHFFFAOYSA-N 50162787 4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid::CHEMBL368448 Cytochrome P450 26A1 Homo sapiens 3.3 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162787&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11750760 104048901 CHEMBL368448 ZINC28335882 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300150 COC(=O)c1cccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)c1 InChI=1S/C27H29N3O3/c1-19(29(2)3)26(30-13-12-28-18-30)23-9-8-22-16-25(11-10-21(22)15-23)33-17-20-6-5-7-24(14-20)27(31)32-4/h5-16,18-19,26H,17H2,1-4H3 FHATZVOKYMKNGI-UHFFFAOYSA-N 50162788 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid methyl ester::CHEMBL181309 Cytochrome P450 26A1 Homo sapiens 7 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162788&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11510548 104048902 CHEMBL181309 ZINC28340102 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300151 COC(=O)COc1ccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)cc1 InChI=1S/C28H31N3O4/c1-20(30(2)3)28(31-14-13-29-19-31)24-8-7-23-16-26(12-9-22(23)15-24)34-17-21-5-10-25(11-6-21)35-18-27(32)33-4/h5-16,19-20,28H,17-18H2,1-4H3 VXPLIKXVYZZBFD-UHFFFAOYSA-N 50162778 CHEMBL362412::{4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-phenoxy}-acetic acid methyl ester Cytochrome P450 26A1 Homo sapiens 19 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162778&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390161 104048892 CHEMBL362412 ZINC28338371 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300152 CC(C(c1ccc2cc(OCc3ccc(cc3)C#N)ccc2c1)n1ccnc1)N(C)C InChI=1S/C26H26N4O/c1-19(29(2)3)26(30-13-12-28-18-30)24-9-8-23-15-25(11-10-22(23)14-24)31-17-21-6-4-20(16-27)5-7-21/h4-15,18-19,26H,17H2,1-3H3 MUCJLTBRRVGZER-UHFFFAOYSA-N 50162791 4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzonitrile::CHEMBL359627 Cytochrome P450 26A1 Homo sapiens 6 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162791&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11690073 104048905 CHEMBL359627 ZINC28127335 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300153 CC(C(c1ccc2cc(OCc3cccc(c3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C26H27N3O3/c1-18(28(2)3)25(29-12-11-27-17-29)22-8-7-21-15-24(10-9-20(21)14-22)32-16-19-5-4-6-23(13-19)26(30)31/h4-15,17-18,25H,16H2,1-3H3,(H,30,31) LUDUPPNOCMHNSY-UHFFFAOYSA-N 50162776 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid::CHEMBL426789 Cytochrome P450 26A1 Homo sapiens 3.5 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162776&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11235737 104048890 CHEMBL426789 ZINC28344228 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300154 COC(=O)Cc1ccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)cc1 InChI=1S/C28H31N3O3/c1-20(30(2)3)28(31-14-13-29-19-31)25-10-9-24-17-26(12-11-23(24)16-25)34-18-22-7-5-21(6-8-22)15-27(32)33-4/h5-14,16-17,19-20,28H,15,18H2,1-4H3 GMYMOUHNOWZKMI-UHFFFAOYSA-N 50162783 CHEMBL179825::{4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-phenyl}-acetic acid methyl ester Cytochrome P450 26A1 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162783&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11633939 104048897 CHEMBL179825 ZINC28335716 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300157 COC(=O)c1ccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)cc1 InChI=1S/C27H29N3O3/c1-19(29(2)3)26(30-14-13-28-18-30)24-10-9-23-16-25(12-11-22(23)15-24)33-17-20-5-7-21(8-6-20)27(31)32-4/h5-16,18-19,26H,17H2,1-4H3 SNSYASMKLBWRLR-UHFFFAOYSA-N 50162793 4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid methyl ester::CHEMBL178474 Cytochrome P450 26A1 Homo sapiens 16.0 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162793&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11495962 104048907 CHEMBL178474 ZINC28130829 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300158 CC(C(c1ccc2cc(OCc3ccccc3)ccc2c1)n1ccnc1)N(C)C InChI=1S/C25H27N3O/c1-19(27(2)3)25(28-14-13-26-18-28)23-10-9-22-16-24(12-11-21(22)15-23)29-17-20-7-5-4-6-8-20/h4-16,18-19,25H,17H2,1-3H3 XNPARDFAECDMGN-UHFFFAOYSA-N 50162789 CHEMBL180856::[2-(6-Benzyloxy-naphthalen-2-yl)-2-imidazol-1-yl-1-methyl-ethyl]-dimethyl-amine Cytochrome P450 26A1 Homo sapiens 50 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162789&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390134 104048903 CHEMBL180856 ZINC28344611 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300159 CC(C(c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C23H29N3O3/c1-16(25(4)5)21(26-11-10-24-15-26)19-7-6-18-13-20(9-8-17(18)12-19)29-14-23(2,3)22(27)28/h6-13,15-16,21H,14H2,1-5H3,(H,27,28) YLMRCYCGLCIPMC-UHFFFAOYSA-N 50162773 3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid::CHEMBL360771 Cytochrome P450 26A1 Homo sapiens 20.0 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162773&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11773824 104048888 CHEMBL360771 ZINC38363348 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300161 CC(C(c1ccc2cc(OCc3cccc(c3)C(N)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C26H28N4O2/c1-18(29(2)3)25(30-12-11-28-17-30)22-8-7-21-15-24(10-9-20(21)14-22)32-16-19-5-4-6-23(13-19)26(27)31/h4-15,17-18,25H,16H2,1-3H3,(H2,27,31) GNOBXZHCXJWOKL-UHFFFAOYSA-N 50162786 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzamide::CHEMBL360148 Cytochrome P450 26A1 Homo sapiens 48 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162786&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390206 104048900 CHEMBL360148 ZINC28344458 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300162 CC(C(c1ccc2cc(OCC(C)(C)C(N)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C23H30N4O2/c1-16(26(4)5)21(27-11-10-25-15-27)19-7-6-18-13-20(9-8-17(18)12-19)29-14-23(2,3)22(24)28/h6-13,15-16,21H,14H2,1-5H3,(H2,24,28) OZXGHWIQASWJQX-UHFFFAOYSA-N 50162792 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionamide::CHEMBL362489 Cytochrome P450 26A1 Homo sapiens 47 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162792&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11406760 104048906 CHEMBL362489 ZINC28332504 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300169 CNC(=O)C(C)(C)COc1ccc2cc(ccc2c1)C(C(C)N(C)C)n1ccnc1 InChI=1S/C24H32N4O2/c1-17(27(5)6)22(28-12-11-26-16-28)20-8-7-19-14-21(10-9-18(19)13-20)30-15-24(2,3)23(29)25-4/h7-14,16-17,22H,15H2,1-6H3,(H,25,29) LEDOEMLBTIQWQV-UHFFFAOYSA-N 50162779 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-2,2,N-trimethyl-propionamide::CHEMBL180829 Cytochrome P450 26A1 Homo sapiens 54 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162779&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11475327 104048893 CHEMBL180829 ZINC28137096 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300170 CC(C(c1ccc2cc(OCC(C)(C)C)ccc2c1)n1ccnc1)N(C)C InChI=1S/C23H31N3O/c1-17(25(5)6)22(26-12-11-24-16-26)20-8-7-19-14-21(10-9-18(19)13-20)27-15-23(2,3)4/h7-14,16-17,22H,15H2,1-6H3 ZZGVWUSRXVYCSC-UHFFFAOYSA-N 50162777 CHEMBL180805::{2-[6-(2,2-Dimethyl-propoxy)-naphthalen-2-yl]-2-imidazol-1-yl-1-methyl-ethyl}-dimethyl-amine Cytochrome P450 26A1 Homo sapiens 21.4 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162777&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11501485 104048891 CHEMBL180805 ZINC28344021 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300171 CC(C(c1ccc2cc(OCC(C)(C)C(=O)N(C)C)ccc2c1)n1ccnc1)N(C)C InChI=1S/C25H34N4O2/c1-18(27(4)5)23(29-13-12-26-17-29)21-9-8-20-15-22(11-10-19(20)14-21)31-16-25(2,3)24(30)28(6)7/h8-15,17-18,23H,16H2,1-7H3 RSDPLFJFCIEHAP-UHFFFAOYSA-N 50162775 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-2,2,N,N-tetramethyl-propionamide::CHEMBL367357 Cytochrome P450 26A1 Homo sapiens 35 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162775&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11441615 104048889 CHEMBL367357 ZINC28331462 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300172 COC(=O)c1ccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)cc1 InChI=1S/C27H29N3O3/c1-19(29(2)3)26(30-14-13-28-18-30)24-10-9-23-16-25(12-11-22(23)15-24)33-17-20-5-7-21(8-6-20)27(31)32-4/h5-16,18-19,26H,17H2,1-4H3 SNSYASMKLBWRLR-UHFFFAOYSA-N 50162793 4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid methyl ester::CHEMBL178474 Cytochrome P450 26A1 Homo sapiens 16 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162793&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11495962 104048907 CHEMBL178474 ZINC28130829 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50300173 CC(C(c1ccc2cc(OCc3ccc(cc3)C#N)ccc2c1)n1ccnc1)N(C)C InChI=1S/C26H26N4O/c1-19(29(2)3)26(30-13-12-28-18-30)24-9-8-23-15-25(11-10-22(23)14-24)31-17-21-6-4-20(16-27)5-7-21/h4-15,18-19,26H,17H2,1-3H3 MUCJLTBRRVGZER-UHFFFAOYSA-N 50162791 4-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzonitrile::CHEMBL359627 Cytochrome P450 26A1 Homo sapiens 6.00 ChEMBL 10.1016/j.bmcl.2005.01.044 10.7270/Q2WW7H5R 15745819 Mulvihill, MJ; Kan, JL; Beck, P; Bittner, M; Cesario, C; Cooke, A; Keane, DM; Nigro, AI; Nillson, C; Smith, V; Srebernak, M; Sun, FL; Vrkljan, M; Winski, SL; Castelhano, AL; Emerson, D; Gibson, N OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162791&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11690073 104048905 CHEMBL359627 ZINC28127335 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297019 Cc1nn(c(Cl)c1C(=O)NC(CC(O)=O)c1ccc(Cl)c(Cl)c1)-c1ccccc1 InChI=1S/C20H16Cl3N3O3/c1-11-18(19(23)26(25-11)13-5-3-2-4-6-13)20(29)24-16(10-17(27)28)12-7-8-14(21)15(22)9-12/h2-9,16H,10H2,1H3,(H,24,29)(H,27,28) BAIIMTYXDPYJJW-UHFFFAOYSA-N 50063066 CHEMBL3398417 Cytochrome P450 26A1 Homo sapiens 2070 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063066&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727469 313070974 CHEMBL3398417 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297020 Cc1cc(C(=O)NC(CC(O)=O)c2cccc(C)c2)c(C)o1 InChI=1S/C17H19NO4/c1-10-5-4-6-13(7-10)15(9-16(19)20)18-17(21)14-8-11(2)22-12(14)3/h4-8,15H,9H2,1-3H3,(H,18,21)(H,19,20) PRYMFKVJZPYCDG-UHFFFAOYSA-N 50063067 CHEMBL3398411 Cytochrome P450 26A1 Homo sapiens 3140 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063067&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727463 313070975 CHEMBL3398411 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297021 CC(C)c1ccc(cc1)C(CC(O)=O)NC(=O)c1cc(C)oc1C InChI=1S/C19H23NO4/c1-11(2)14-5-7-15(8-6-14)17(10-18(21)22)20-19(23)16-9-12(3)24-13(16)4/h5-9,11,17H,10H2,1-4H3,(H,20,23)(H,21,22) QHAACUUOYSPEHD-UHFFFAOYSA-N 50063068 CHEMBL3398410 Cytochrome P450 26A1 Homo sapiens 4020 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063068&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727462 313070976 CHEMBL3398410 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297022 Cc1cc(C(=O)NC(CC(O)=O)c2ccc(Cl)cc2)c(C)o1 InChI=1S/C16H16ClNO4/c1-9-7-13(10(2)22-9)16(21)18-14(8-15(19)20)11-3-5-12(17)6-4-11/h3-7,14H,8H2,1-2H3,(H,18,21)(H,19,20) QMBBVWSDUBOAJA-UHFFFAOYSA-N 50063069 CHEMBL3398409 Cytochrome P450 26A1 Homo sapiens 2730 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063069&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727461 313070977 CHEMBL3398409 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297023 Cc1cc(C(=O)NC(CC(O)=O)c2ccc(C)cc2)c(C)o1 InChI=1S/C17H19NO4/c1-10-4-6-13(7-5-10)15(9-16(19)20)18-17(21)14-8-11(2)22-12(14)3/h4-8,15H,9H2,1-3H3,(H,18,21)(H,19,20) PUXSXDUFGWKOIY-UHFFFAOYSA-N 50063070 CHEMBL3398408 Cytochrome P450 26A1 Homo sapiens 3090 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063070&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727460 313070978 CHEMBL3398408 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297024 Cc1cc(C(=O)NC(CC(O)=O)c2ccc(Cl)c(Cl)c2)c(C)o1 InChI=1S/C16H15Cl2NO4/c1-8-5-11(9(2)23-8)16(22)19-14(7-15(20)21)10-3-4-12(17)13(18)6-10/h3-6,14H,7H2,1-2H3,(H,19,22)(H,20,21) PAKYXZHVOCIMNW-UHFFFAOYSA-N 50063072 CHEMBL3398407 Cytochrome P450 26A1 Homo sapiens 2830 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063072&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727459 313070979 CHEMBL3398407 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297025 Cc1nn(c(Cl)c1C(=O)NC(CC(O)=O)c1ccccc1Br)-c1ccccc1 InChI=1S/C20H17BrClN3O3/c1-12-18(19(22)25(24-12)13-7-3-2-4-8-13)20(28)23-16(11-17(26)27)14-9-5-6-10-15(14)21/h2-10,16H,11H2,1H3,(H,23,28)(H,26,27) PIFQQJXMIZARQP-UHFFFAOYSA-N 50063073 CHEMBL3398418 Cytochrome P450 26A1 Homo sapiens 1360 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063073&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727470 313070980 CHEMBL3398418 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297026 CC(C)c1ccc(cc1)C(CC(O)=O)NC(=O)c1cc(oc1C)C(C)(C)C InChI=1S/C22H29NO4/c1-13(2)15-7-9-16(10-8-15)18(12-20(24)25)23-21(26)17-11-19(22(4,5)6)27-14(17)3/h7-11,13,18H,12H2,1-6H3,(H,23,26)(H,24,25) FXCLQYZAEAKOQB-UHFFFAOYSA-N 50063074 CHEMBL3398406 Cytochrome P450 26A1 Homo sapiens 5070 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063074&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727458 313070981 CHEMBL3398406 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297027 Cc1oc(cc1C(=O)NC(CC(O)=O)c1ccc(Cl)cc1)C(C)(C)C InChI=1S/C19H22ClNO4/c1-11-14(9-16(25-11)19(2,3)4)18(24)21-15(10-17(22)23)12-5-7-13(20)8-6-12/h5-9,15H,10H2,1-4H3,(H,21,24)(H,22,23) IYKAHCFNTYFAON-UHFFFAOYSA-N 50063075 CHEMBL3398405 Cytochrome P450 26A1 Homo sapiens 3020 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063075&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727457 313070982 CHEMBL3398405 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297028 Cc1nn(c(Cl)c1C(=O)NC(CC(O)=O)c1cccc(Br)c1)-c1ccccc1 InChI=1S/C20H17BrClN3O3/c1-12-18(19(22)25(24-12)15-8-3-2-4-9-15)20(28)23-16(11-17(26)27)13-6-5-7-14(21)10-13/h2-10,16H,11H2,1H3,(H,23,28)(H,26,27) JXOZYSYRONBTKN-UHFFFAOYSA-N 50063076 CHEMBL3398420 Cytochrome P450 26A1 Homo sapiens 1870 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063076&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727472 313070983 CHEMBL3398420 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297029 Cc1oc(cc1C(=O)NC(CC(O)=O)c1ccccc1)C(C)(C)C InChI=1S/C19H23NO4/c1-12-14(10-16(24-12)19(2,3)4)18(23)20-15(11-17(21)22)13-8-6-5-7-9-13/h5-10,15H,11H2,1-4H3,(H,20,23)(H,21,22) DIKPQFGATRYVCD-UHFFFAOYSA-N 50063077 CHEMBL3398421 Cytochrome P450 26A1 Homo sapiens 3210 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063077&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727473 313070984 CHEMBL3398421 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297030 Cc1nn(c(Cl)c1C(=O)NC(CC(O)=O)c1ccc(cc1)C(C)(C)C)-c1ccccc1 InChI=1S/C24H26ClN3O3/c1-15-21(22(25)28(27-15)18-8-6-5-7-9-18)23(31)26-19(14-20(29)30)16-10-12-17(13-11-16)24(2,3)4/h5-13,19H,14H2,1-4H3,(H,26,31)(H,29,30) MZIXNJVVDALVHH-UHFFFAOYSA-N 50063078 CHEMBL3398419 Cytochrome P450 26A1 Homo sapiens 3220 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063078&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727471 313070985 CHEMBL3398419 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297031 Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50176808 5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benzoimidazole::6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL389433::US9138393, Liarizole hydrochloride::US9144538, Liarizole hydrochloride::liarozole Cytochrome P450 26A1 Homo sapiens 2450 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176808&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 104062424 CHEMBL389433 5210 ZINC11687637 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297032 Cc1oc(cc1C(=O)NC(CC(O)=O)c1cccc(F)c1)C(C)(C)C InChI=1S/C19H22FNO4/c1-11-14(9-16(25-11)19(2,3)4)18(24)21-15(10-17(22)23)12-6-5-7-13(20)8-12/h5-9,15H,10H2,1-4H3,(H,21,24)(H,22,23) XCQYBSGOXSMAQW-UHFFFAOYSA-N 50063079 CHEMBL3398404 Cytochrome P450 26A1 Homo sapiens 2810 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063079&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727456 313070986 CHEMBL3398404 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297033 Cc1oc(cc1C(=O)NC(CC(O)=O)c1ccc(Cl)c(Cl)c1)C(C)(C)C InChI=1S/C19H21Cl2NO4/c1-10-12(8-16(26-10)19(2,3)4)18(25)22-15(9-17(23)24)11-5-6-13(20)14(21)7-11/h5-8,15H,9H2,1-4H3,(H,22,25)(H,23,24) KFZQDDRSBVXHPH-UHFFFAOYSA-N 50063080 CHEMBL3398403 Cytochrome P450 26A1 Homo sapiens 2620 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063080&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727455 313070987 CHEMBL3398403 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297034 Cc1oc(cc1C(=O)NC(CC(O)=O)c1ccc(C)cc1)C(C)(C)C InChI=1S/C20H25NO4/c1-12-6-8-14(9-7-12)16(11-18(22)23)21-19(24)15-10-17(20(3,4)5)25-13(15)2/h6-10,16H,11H2,1-5H3,(H,21,24)(H,22,23) XPRQEFPTFTXAHY-UHFFFAOYSA-N 50063081 CHEMBL3398402 Cytochrome P450 26A1 Homo sapiens 3260 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063081&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727454 313070988 CHEMBL3398402 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297035 Cc1oc(cc1C(=O)NC(CC(O)=O)c1cccc(c1)[N+]([O-])=O)C(C)(C)C InChI=1S/C19H22N2O6/c1-11-14(9-16(27-11)19(2,3)4)18(24)20-15(10-17(22)23)12-6-5-7-13(8-12)21(25)26/h5-9,15H,10H2,1-4H3,(H,20,24)(H,22,23) CXLWBDWOXGMOJR-UHFFFAOYSA-N 50063082 CHEMBL3398401 Cytochrome P450 26A1 Homo sapiens 3040 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063082&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727453 313070989 CHEMBL3398401 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297036 CCCn1c(C)c(cc1C(C)(C)C)C(=O)NC(CC(O)=O)c1ccc(OC)cc1 InChI=1S/C23H32N2O4/c1-7-12-25-15(2)18(13-20(25)23(3,4)5)22(28)24-19(14-21(26)27)16-8-10-17(29-6)11-9-16/h8-11,13,19H,7,12,14H2,1-6H3,(H,24,28)(H,26,27) PQBPOBCLHYABRI-UHFFFAOYSA-N 50063083 CHEMBL3398416 Cytochrome P450 26A1 Homo sapiens 3480 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063083&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727468 313070990 CHEMBL3398416 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297037 Cc1cc(C(=O)NC(CC(O)=O)c2ccccc2Br)c(C)o1 InChI=1S/C16H16BrNO4/c1-9-7-12(10(2)22-9)16(21)18-14(8-15(19)20)11-5-3-4-6-13(11)17/h3-7,14H,8H2,1-2H3,(H,18,21)(H,19,20) XBBWMQSINIVFNN-UHFFFAOYSA-N 50063084 CHEMBL3398412 Cytochrome P450 26A1 Homo sapiens 2340 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063084&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727464 313070991 CHEMBL3398412 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297038 CCCn1c(C)c(cc1C(C)(C)C)C(=O)NC(CC(O)=O)c1ccccc1Br InChI=1S/C22H29BrN2O3/c1-6-11-25-14(2)16(12-19(25)22(3,4)5)21(28)24-18(13-20(26)27)15-9-7-8-10-17(15)23/h7-10,12,18H,6,11,13H2,1-5H3,(H,24,28)(H,26,27) MSYNTHZKJVOLFH-UHFFFAOYSA-N 50063085 CHEMBL3398413 Cytochrome P450 26A1 Homo sapiens 3130 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063085&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727465 313070992 CHEMBL3398413 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297039 CCCn1c(C)c(cc1C(C)(C)C)C(=O)NC(CC(O)=O)c1ccc(cc1)C(C)(C)C InChI=1S/C26H38N2O3/c1-9-14-28-17(2)20(15-22(28)26(6,7)8)24(31)27-21(16-23(29)30)18-10-12-19(13-11-18)25(3,4)5/h10-13,15,21H,9,14,16H2,1-8H3,(H,27,31)(H,29,30) FOGURFTYQYAJDN-UHFFFAOYSA-N 50063086 CHEMBL3398414 Cytochrome P450 26A1 Homo sapiens 5190 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063086&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727466 313070993 CHEMBL3398414 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50297040 CCCn1c(C)c(cc1C(C)(C)C)C(=O)NC(CC(O)=O)c1ccccc1[N+]([O-])=O InChI=1S/C22H29N3O5/c1-6-11-24-14(2)16(12-19(24)22(3,4)5)21(28)23-17(13-20(26)27)15-9-7-8-10-18(15)25(29)30/h7-10,12,17H,6,11,13H2,1-5H3,(H,23,28)(H,26,27) QKBGNKYRVAGQBM-UHFFFAOYSA-N 50063087 CHEMBL3398415 Cytochrome P450 26A1 Homo sapiens 3350 ChEMBL 10.1016/j.bmc.2014.11.036 10.7270/Q2416ZQG 25684424 Zhao, D; Sun, B; Ren, J; Li, F; Song, S; Lv, X; Hao, C; Cheng, M Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063087&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 118727467 313070994 CHEMBL3398415 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339163 CCN(CC)[C@H](C)[C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C25H33N3O3/c1-6-27(7-2)18(3)23(28-13-12-26-17-28)21-9-8-20-15-22(11-10-19(20)14-21)31-16-25(4,5)24(29)30/h8-15,17-18,23H,6-7,16H2,1-5H3,(H,29,30)/t18-,23+/m1/s1 ACFQJABFUNOOOS-JPYJTQIMSA-N 50183225 3-(6-((1R,2R)-2-(diethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL208155 Cytochrome P450 26A1 Homo sapiens 5 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183225&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410862 104067762 CHEMBL208155 ZINC40564992 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339166 CC(C)N(C)[C@H](C)[C@@H](c1ccc2cc(OCC3(CCCC3)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C27H35N3O3/c1-19(2)29(4)20(3)25(30-14-13-28-18-30)23-8-7-22-16-24(10-9-21(22)15-23)33-17-27(26(31)32)11-5-6-12-27/h7-10,13-16,18-20,25H,5-6,11-12,17H2,1-4H3,(H,31,32)/t20-,25+/m1/s1 MYLJXYCXVOMQPS-NLFFAJNJSA-N 50183229 1-((6-((1R,2R)-1-(1H-imidazol-1-yl)-2-(isopropyl(methyl)amino)propyl)naphthalen-2-yloxy)methyl)cyclopentanecarboxylic acid::CHEMBL207304 Cytochrome P450 26A1 Homo sapiens 1.6 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183229&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410814 104067766 CHEMBL207304 ZINC40564282 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339167 C[C@H]([C@@H](c1ccc2cc(OCC3(CCCCC3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C26H33N3O3/c1-19(28(2)3)24(29-14-13-27-18-29)22-8-7-21-16-23(10-9-20(21)15-22)32-17-26(25(30)31)11-5-4-6-12-26/h7-10,13-16,18-19,24H,4-6,11-12,17H2,1-3H3,(H,30,31)/t19-,24+/m1/s1 VZAYORFJMPOFKB-DVECYGJZSA-N 50183230 1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)cyclohexanecarboxylic acid::CHEMBL207638 Cytochrome P450 26A1 Homo sapiens 11 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183230&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410841 104067767 CHEMBL207638 ZINC34565910 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339169 CN(C)C(C)(C)[C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C24H31N3O3/c1-23(2,22(28)29)15-30-20-10-9-17-13-19(8-7-18(17)14-20)21(24(3,4)26(5)6)27-12-11-25-16-27/h7-14,16,21H,15H2,1-6H3,(H,28,29)/t21-/m1/s1 ZJCPXNRESMOODE-OAQYLSRUSA-N 50183232 (R)-3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)-2-methylpropyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL382574 Cytochrome P450 26A1 Homo sapiens 26 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183232&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44411116 104067769 CHEMBL382574 ZINC40763407 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339170 C[C@H]([C@@H](c1ccc2cc(OCC3(CC3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C23H27N3O3/c1-16(25(2)3)21(26-11-10-24-15-26)19-5-4-18-13-20(7-6-17(18)12-19)29-14-23(8-9-23)22(27)28/h4-7,10-13,15-16,21H,8-9,14H2,1-3H3,(H,27,28)/t16-,21+/m1/s1 PVEQEQGWTRAWFX-IERDGZPVSA-N 50183233 1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)cyclopropanecarboxylic acid::CHEMBL206884 Cytochrome P450 26A1 Homo sapiens 35 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183233&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410808 104067770 CHEMBL206884 ZINC40564042 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339171 C[C@H]([C@@H](c1ccc2cc(OCC3(CCCC3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C25H31N3O3/c1-18(27(2)3)23(28-13-12-26-17-28)21-7-6-20-15-22(9-8-19(20)14-21)31-16-25(24(29)30)10-4-5-11-25/h6-9,12-15,17-18,23H,4-5,10-11,16H2,1-3H3,(H,29,30)/t18-,23+/m1/s1 JZBAXRLBKQTQQE-JPYJTQIMSA-N 50183228 1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)cyclopentanecarboxylic acid::CHEMBL377177 Cytochrome P450 26A1 Homo sapiens 7.3 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183228&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410840 104067765 CHEMBL377177 ZINC40763218 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339175 C[C@H]([C@@H](c1ccc2cc(OCC3(CCOCC3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C25H31N3O4/c1-18(27(2)3)23(28-11-10-26-17-28)21-5-4-20-15-22(7-6-19(20)14-21)32-16-25(24(29)30)8-12-31-13-9-25/h4-7,10-11,14-15,17-18,23H,8-9,12-13,16H2,1-3H3,(H,29,30)/t18-,23+/m1/s1 MLPHGOPXOJDNLS-JPYJTQIMSA-N 50183235 4-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)-tetrahydro-2H-pyran-4-carboxylic acid::CHEMBL378132 Cytochrome P450 26A1 Homo sapiens 47 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183235&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410860 104067772 CHEMBL378132 ZINC40762411 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339176 C[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N1CCCC1 InChI=1S/C25H31N3O3/c1-18(27-11-4-5-12-27)23(28-13-10-26-17-28)21-7-6-20-15-22(9-8-19(20)14-21)31-16-25(2,3)24(29)30/h6-10,13-15,17-18,23H,4-5,11-12,16H2,1-3H3,(H,29,30)/t18-,23+/m1/s1 YVRFLLOKSKSKOM-JPYJTQIMSA-N 50183236 3-(6-((1R,2R)-1-(1H-imidazol-1-yl)-2-(pyrrolidin-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL210569 Cytochrome P450 26A1 Homo sapiens 583 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183236&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410812 104067773 CHEMBL210569 ZINC38319872 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339178 CC[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C24H31N3O3/c1-6-21(26(4)5)22(27-12-11-25-16-27)19-8-7-18-14-20(10-9-17(18)13-19)30-15-24(2,3)23(28)29/h7-14,16,21-22H,6,15H2,1-5H3,(H,28,29)/t21-,22-/m1/s1 ZCIYBFFBVPVYLH-FGZHOGPDSA-N 50183224 3-[6-(2-dimethylamino-1-imidazol-1-yl-butyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid::CHEMBL208443 Cytochrome P450 26A1 Homo sapiens 1.3 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183224&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11315814 104067761 CHEMBL208443 ZINC35932967 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339180 C[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C23H29N3O3/c1-16(25(4)5)21(26-11-10-24-15-26)19-7-6-18-13-20(9-8-17(18)12-19)29-14-23(2,3)22(27)28/h6-13,15-16,21H,14H2,1-5H3,(H,27,28)/t16-,21+/m1/s1 YLMRCYCGLCIPMC-IERDGZPVSA-N 50183226 3-[6-(2-dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid::CHEMBL208154 Cytochrome P450 26A1 Homo sapiens 20 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183226&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410799 104067763 CHEMBL208154 ZINC38363348 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339185 C[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N(C)C1CCCCC1 InChI=1S/C28H37N3O3/c1-20(30(4)24-8-6-5-7-9-24)26(31-15-14-29-19-31)23-11-10-22-17-25(13-12-21(22)16-23)34-18-28(2,3)27(32)33/h10-17,19-20,24,26H,5-9,18H2,1-4H3,(H,32,33)/t20-,26+/m1/s1 ITQXAONDFWOMPJ-IBVKSMDESA-N 50183234 3-(6-((1R,2R)-2-(cyclohexyl(methyl)amino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL207411 Cytochrome P450 26A1 Homo sapiens 125 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183234&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410763 104067771 CHEMBL207411 ZINC40564214 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339186 CCCCN(C)[C@H](C)[C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C26H35N3O3/c1-6-7-13-28(5)19(2)24(29-14-12-27-18-29)22-9-8-21-16-23(11-10-20(21)15-22)32-17-26(3,4)25(30)31/h8-12,14-16,18-19,24H,6-7,13,17H2,1-5H3,(H,30,31)/t19-,24+/m1/s1 JHXQEUXIBMCBIF-DVECYGJZSA-N 50183238 3-(6-((1R,2R)-2-(butyl(methyl)amino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL205280 Cytochrome P450 26A1 Homo sapiens 60 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183238&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44411032 104067775 CHEMBL205280 ZINC40556596 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339188 CC(C)N(C)[C@H](C)[C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C25H33N3O3/c1-17(2)27(6)18(3)23(28-12-11-26-16-28)21-8-7-20-14-22(10-9-19(20)13-21)31-15-25(4,5)24(29)30/h7-14,16-18,23H,15H2,1-6H3,(H,29,30)/t18-,23+/m1/s1 GVLPJHAOLSTQRA-JPYJTQIMSA-N 50183237 3-(6-((1R,2R)-1-(1H-imidazol-1-yl)-2-(isopropyl(methyl)amino)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL207486 Cytochrome P450 26A1 Homo sapiens 3 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183237&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410871 104067774 CHEMBL207486 ZINC38334637 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339189 CCC(CC)(COc1ccc2cc(ccc2c1)[C@H]([C@@H](C)N(C)C)n1ccnc1)C(O)=O InChI=1S/C25H33N3O3/c1-6-25(7-2,24(29)30)16-31-22-11-10-19-14-21(9-8-20(19)15-22)23(18(3)27(4)5)28-13-12-26-17-28/h8-15,17-18,23H,6-7,16H2,1-5H3,(H,29,30)/t18-,23+/m1/s1 PLXKSCLQIJZCDI-JPYJTQIMSA-N 50183239 2-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)-2-ethylbutanoic acid::CHEMBL377286 Cytochrome P450 26A1 Homo sapiens 37 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183239&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410807 104067776 CHEMBL377286 ZINC40763294 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339191 CCN(C)[C@H](C)[C@@H](c1ccc2cc(OCC3(CCCC3)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C26H33N3O3/c1-4-28(3)19(2)24(29-14-13-27-18-29)22-8-7-21-16-23(10-9-20(21)15-22)32-17-26(25(30)31)11-5-6-12-26/h7-10,13-16,18-19,24H,4-6,11-12,17H2,1-3H3,(H,30,31)/t19-,24+/m1/s1 IVTCSKRCJOCTBF-DVECYGJZSA-N 50183231 1-((6-((1R,2R)-2-(ethyl(methyl)amino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)cyclopentanecarboxylic acid::CHEMBL207942 Cytochrome P450 26A1 Homo sapiens 4.2 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183231&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11719046 104067768 CHEMBL207942 ZINC34642621 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339192 CCN(C)[C@H](C)[C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C24H31N3O3/c1-6-26(5)17(2)22(27-12-11-25-16-27)20-8-7-19-14-21(10-9-18(19)13-20)30-15-24(3,4)23(28)29/h7-14,16-17,22H,6,15H2,1-5H3,(H,28,29)/t17-,22+/m1/s1 ZXPSJDOWBKNEAW-VGSWGCGISA-N 50183241 3-(6-((1R,2R)-2-(ethyl(methyl)amino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL210780 Cytochrome P450 26A1 Homo sapiens 9 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183241&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410861 104067778 CHEMBL210780 ZINC40566162 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339197 C[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N1CCOCC1 InChI=1S/C25H31N3O4/c1-18(27-10-12-31-13-11-27)23(28-9-8-26-17-28)21-5-4-20-15-22(7-6-19(20)14-21)32-16-25(2,3)24(29)30/h4-9,14-15,17-18,23H,10-13,16H2,1-3H3,(H,29,30)/t18-,23+/m1/s1 ATTJXWVUQQZVGI-JPYJTQIMSA-N 50183242 3-(6-((1R,2R)-1-(1H-imidazol-1-yl)-2-morpholinopropyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL208158 Cytochrome P450 26A1 Homo sapiens 34 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183242&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44411036 104067779 CHEMBL208158 ZINC40565020 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339203 CCN(CC)[C@H](C)[C@@H](c1ccc2cc(OCC3(CCCC3)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C27H35N3O3/c1-4-29(5-2)20(3)25(30-15-14-28-19-30)23-9-8-22-17-24(11-10-21(22)16-23)33-18-27(26(31)32)12-6-7-13-27/h8-11,14-17,19-20,25H,4-7,12-13,18H2,1-3H3,(H,31,32)/t20-,25+/m1/s1 OWYKGJWNYSCISK-NLFFAJNJSA-N 50183243 1-((6-((1R,2R)-2-(diethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)cyclopentanecarboxylic acid::CHEMBL205862 Cytochrome P450 26A1 Homo sapiens 1.4 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183243&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44411109 104067780 CHEMBL205862 ZINC40563756 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339204 C[C@H]([C@@H](c1ccc2cc(OCC3(CCC3)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C24H29N3O3/c1-17(26(2)3)22(27-12-11-25-16-27)20-6-5-19-14-21(8-7-18(19)13-20)30-15-24(23(28)29)9-4-10-24/h5-8,11-14,16-17,22H,4,9-10,15H2,1-3H3,(H,28,29)/t17-,22+/m1/s1 WNMJTTIGNYLSJY-VGSWGCGISA-N 50183227 1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)cyclobutanecarboxylic acid::CHEMBL207345 Cytochrome P450 26A1 Homo sapiens 40 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183227&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44410881 104067764 CHEMBL207345 ZINC40564790 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50339211 CN(C)C[C@@H](c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1 InChI=1S/C22H27N3O3/c1-22(2,21(26)27)14-28-19-8-7-16-11-18(6-5-17(16)12-19)20(13-24(3)4)25-10-9-23-15-25/h5-12,15,20H,13-14H2,1-4H3,(H,26,27)/t20-/m0/s1 VINGQXPBSLYVAK-FQEVSTJZSA-N 50183240 (R)-3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)ethyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::CHEMBL204684 Cytochrome P450 26A1 Homo sapiens 403 ChEMBL 10.1016/j.bmcl.2006.02.020 10.7270/Q24Q7TK9 16504501 Mulvihill, MJ; Kan, JL; Cooke, A; Bhagwat, S; Beck, P; Bittner, M; Cesario, C; Keane, D; Lazarescu, V; Nigro, A; Nillson, C; Panicker, B; Smith, V; Srebernak, M; Sun, FL; O'Connor, M; Russo, S; Fischetti, G; Vrkljan, M; Winski, S; Castelhano, AL; Emerson, D; Gibson, NW OSI Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183240&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44411110 104067777 CHEMBL204684 ZINC35996750 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410989 CC(C(c1ccc2cc(OCc3ccccc3)ccc2c1)n1ccnc1)N(C)C InChI=1S/C25H27N3O/c1-19(27(2)3)25(28-14-13-26-18-28)23-10-9-22-16-24(12-11-21(22)15-23)29-17-20-7-5-4-6-8-20/h4-16,18-19,25H,17H2,1-3H3 XNPARDFAECDMGN-UHFFFAOYSA-N 50162789 CHEMBL180856::[2-(6-Benzyloxy-naphthalen-2-yl)-2-imidazol-1-yl-1-methyl-ethyl]-dimethyl-amine Cytochrome P450 26A1 Homo sapiens 50 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162789&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44390134 104048903 CHEMBL180856 ZINC28344611 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410990 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C25H25N3O2/c1-25(2,24(29)30-3)23(28-15-14-26-17-28)19-9-11-21(12-10-19)27-22-13-8-18-6-4-5-7-20(18)16-22/h4-17,23,27H,1-3H3 MTHVGGMOKYRPIO-UHFFFAOYSA-N 50342128 3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamino)-phenyl]-propionicAcid Methyl Ester::CHEMBL1766005 Cytochrome P450 26A1 Homo sapiens 3.0 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342128&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 54581365 131345064 CHEMBL1766005 ZINC68153322 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410991 CCC(CC)[C@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25)/t20-/m1/s1 SNFYYXUGUBUECJ-HXUWFJFHSA-N 50377963 CHEMBL224305::R-115866 Cytochrome P450 26A1 Homo sapiens 4.0 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377963&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44421596 160857046 CHEMBL224305 ZINC13675264 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410992 CC(C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1)N(C)C InChI=1S/C20H22N6S/c1-14(25(2)3)19(26-13-21-12-22-26)15-8-10-16(11-9-15)23-20-24-17-6-4-5-7-18(17)27-20/h4-14,19H,1-3H3,(H,23,24) PJNAJZSNGGHTRM-UHFFFAOYSA-N 50120455 CHEMBL3617993 Cytochrome P450 26A1 Homo sapiens 10.0 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120455&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9821132 319565974 CHEMBL3617993 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410993 COC(=O)C(Cn1ccnc1)NC(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C20H19N3O3/c1-26-20(25)18(13-23-12-11-21-14-23)22-19(24)17-9-7-16(8-10-17)15-5-3-2-4-6-15/h2-12,14,18H,13H2,1H3,(H,22,24) BGJLLVCRNMWTNA-UHFFFAOYSA-N 50120456 CHEMBL3617978 Cytochrome P450 26A1 Homo sapiens 370 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120456&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190692 319565975 CHEMBL3617978 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410994 CCOC(=O)C(Cn1ccnc1)NC(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C21H21N3O3/c1-2-27-21(26)19(14-24-13-12-22-15-24)23-20(25)18-10-8-17(9-11-18)16-6-4-3-5-7-16/h3-13,15,19H,2,14H2,1H3,(H,23,25) SNBSGSLUOLPOGH-UHFFFAOYSA-N 50120457 CHEMBL3617979 Cytochrome P450 26A1 Homo sapiens 650 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120457&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190693 319565976 CHEMBL3617979 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410995 CCCOC(=O)C(Cn1ccnc1)NC(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C22H23N3O3/c1-2-14-28-22(27)20(15-25-13-12-23-16-25)24-21(26)19-10-8-18(9-11-19)17-6-4-3-5-7-17/h3-13,16,20H,2,14-15H2,1H3,(H,24,26) KRTKBGVAKDCIEF-UHFFFAOYSA-N 50120458 CHEMBL3617980 Cytochrome P450 26A1 Homo sapiens 790 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120458&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190694 319565977 CHEMBL3617980 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410996 CC(C)OC(=O)C(Cn1ccnc1)NC(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C22H23N3O3/c1-16(2)28-22(27)20(14-25-13-12-23-15-25)24-21(26)19-10-8-18(9-11-19)17-6-4-3-5-7-17/h3-13,15-16,20H,14H2,1-2H3,(H,24,26) IRPWNLLRPUUENV-UHFFFAOYSA-N 50120459 CHEMBL3617981 Cytochrome P450 26A1 Homo sapiens 540 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120459&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190695 319565978 CHEMBL3617981 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410997 CC(C)COC(=O)C(Cn1ccnc1)NC(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C23H25N3O3/c1-17(2)15-29-23(28)21(14-26-13-12-24-16-26)25-22(27)20-10-8-19(9-11-20)18-6-4-3-5-7-18/h3-13,16-17,21H,14-15H2,1-2H3,(H,25,27) KRXJOWDVRBTAGW-UHFFFAOYSA-N 50120460 CHEMBL3617982 Cytochrome P450 26A1 Homo sapiens 970 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120460&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190696 319565979 CHEMBL3617982 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410998 COC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(c1Cl)-c1ccccc1 InChI=1S/C18H18ClN5O3/c1-12-15(16(19)24(22-12)13-6-4-3-5-7-13)17(25)21-14(18(26)27-2)10-23-9-8-20-11-23/h3-9,11,14H,10H2,1-2H3,(H,21,25) PYZSBQQHZCMXFK-UHFFFAOYSA-N 50120461 CHEMBL3617983 Cytochrome P450 26A1 Homo sapiens 220 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120461&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190697 319565980 CHEMBL3617983 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50410999 CCOC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(c1Cl)-c1ccccc1 InChI=1S/C19H20ClN5O3/c1-3-28-19(27)15(11-24-10-9-21-12-24)22-18(26)16-13(2)23-25(17(16)20)14-7-5-4-6-8-14/h4-10,12,15H,3,11H2,1-2H3,(H,22,26) LIZHPAXYCBZWTR-UHFFFAOYSA-N 50120463 CHEMBL3617984 Cytochrome P450 26A1 Homo sapiens 600 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120463&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190698 104013532 CHEMBL3617984 ZINC13491887 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411000 CCCOC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(c1Cl)-c1ccccc1 InChI=1S/C20H22ClN5O3/c1-3-11-29-20(28)16(12-25-10-9-22-13-25)23-19(27)17-14(2)24-26(18(17)21)15-7-5-4-6-8-15/h4-10,13,16H,3,11-12H2,1-2H3,(H,23,27) XICINSYJQBPHLD-UHFFFAOYSA-N 50120464 CHEMBL3617985 Cytochrome P450 26A1 Homo sapiens 620 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120464&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190699 104013533 CHEMBL3617985 ZINC00019893 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411001 CC(C)OC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(c1Cl)-c1ccccc1 InChI=1S/C20H22ClN5O3/c1-13(2)29-20(28)16(11-25-10-9-22-12-25)23-19(27)17-14(3)24-26(18(17)21)15-7-5-4-6-8-15/h4-10,12-13,16H,11H2,1-3H3,(H,23,27) CVZOIBZVGKOLJA-UHFFFAOYSA-N 50120466 CHEMBL3617986 Cytochrome P450 26A1 Homo sapiens 460 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120466&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190700 104013535 CHEMBL3617986 ZINC13491888 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411002 CC(C)COC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(c1Cl)-c1ccccc1 InChI=1S/C21H24ClN5O3/c1-14(2)12-30-21(29)17(11-26-10-9-23-13-26)24-20(28)18-15(3)25-27(19(18)22)16-7-5-4-6-8-16/h4-10,13-14,17H,11-12H2,1-3H3,(H,24,28) ZGYRQULAVVNNPK-UHFFFAOYSA-N 50120476 CHEMBL3617987 Cytochrome P450 26A1 Homo sapiens 1020 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120476&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190701 104013545 CHEMBL3617987 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411003 COC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 InChI=1S/C15H14N4O3S/c1-22-15(21)11(8-19-7-6-16-9-19)17-13(20)14-18-10-4-2-3-5-12(10)23-14/h2-7,9,11H,8H2,1H3,(H,17,20) GIKOIMSPMYSKQT-UHFFFAOYSA-N 50120484 CHEMBL3617988 Cytochrome P450 26A1 Homo sapiens 410 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120484&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190702 319565981 CHEMBL3617988 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411013 CCOC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 InChI=1S/C16H16N4O3S/c1-2-23-16(22)12(9-20-8-7-17-10-20)18-14(21)15-19-11-5-3-4-6-13(11)24-15/h3-8,10,12H,2,9H2,1H3,(H,18,21) HIVWJURYEDRGCA-UHFFFAOYSA-N 50120485 CHEMBL3617989 Cytochrome P450 26A1 Homo sapiens 740 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120485&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190703 319565982 CHEMBL3617989 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411014 CCCOC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 InChI=1S/C17H18N4O3S/c1-2-9-24-17(23)13(10-21-8-7-18-11-21)19-15(22)16-20-12-5-3-4-6-14(12)25-16/h3-8,11,13H,2,9-10H2,1H3,(H,19,22) CXWJGKXICVVWEZ-UHFFFAOYSA-N 50120486 CHEMBL3617990 Cytochrome P450 26A1 Homo sapiens 840 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120486&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190704 319565983 CHEMBL3617990 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411015 CC(C)OC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 InChI=1S/C17H18N4O3S/c1-11(2)24-17(23)13(9-21-8-7-18-10-21)19-15(22)16-20-12-5-3-4-6-14(12)25-16/h3-8,10-11,13H,9H2,1-2H3,(H,19,22) LHRLGGIETKGGNS-UHFFFAOYSA-N 50120487 CHEMBL3617991 Cytochrome P450 26A1 Homo sapiens 630 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120487&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190705 319565984 CHEMBL3617991 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411016 CC(C)COC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 InChI=1S/C18H20N4O3S/c1-12(2)10-25-18(24)14(9-22-8-7-19-11-22)20-16(23)17-21-13-5-3-4-6-15(13)26-17/h3-8,11-12,14H,9-10H2,1-2H3,(H,20,23) RDNVIEBJBWYJCN-UHFFFAOYSA-N 50120488 CHEMBL3617992 Cytochrome P450 26A1 Homo sapiens 1110 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120488&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 122190706 319565985 CHEMBL3617992 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50411018 Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50176808 5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benzoimidazole::6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL389433::US9138393, Liarizole hydrochloride::US9144538, Liarizole hydrochloride::liarozole Cytochrome P450 26A1 Homo sapiens 890 ChEMBL 10.1016/j.bmc.2015.08.019 10.7270/Q2668G0C 26365710 Sun, B; Liu, K; Han, J; Zhao, LY; Su, X; Lin, B; Zhao, DM; Cheng, MS Shenyang Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176808&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 104062424 CHEMBL389433 5210 ZINC11687637 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484294 Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26) NAVMQTYZDKMPEU-UHFFFAOYSA-N 50032675 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid::BEXAROTENE::CHEMBL1023::p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid Cytochrome P450 26A1 Homo sapiens 13500 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032675&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9RA 82146 103941130 50859 CHEMBL1023 DB00307 2807 ZINC01539579 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484295 CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(cc1)C(O)=O InChI=1S/C24H28O4/c1-22(2)11-12-23(3,4)20-15-18(9-10-19(20)22)24(27-13-14-28-24)17-7-5-16(6-8-17)21(25)26/h5-10,15H,11-14H2,1-4H3,(H,25,26) ZZUKALQMHNSWTK-UHFFFAOYSA-N 50033077 4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-[1,3]dioxolan-2-yl]-benzoic acid::CHEMBL112715 Cytochrome P450 26A1 Homo sapiens 7800 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033077&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 127019 103941444 CHEMBL112715 2809 ZINC01540632 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484316 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)c1ccc(cc1)C(O)=O InChI=1S/C22H24O3/c1-21(2)11-12-22(3,4)18-13-16(9-10-17(18)21)19(23)14-5-7-15(8-6-14)20(24)25/h5-10,13H,11-12H2,1-4H3,(H,24,25) PBXZHEOVJMPKDY-UHFFFAOYSA-N 50033066 4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-benzoic acid::CHEMBL101308 Cytochrome P450 26A1 Homo sapiens >25000 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033066&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9949645 103941433 CHEMBL101308 ZINC01532939 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484330 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)c1ccc2cc(ccc2c1)C(O)=O InChI=1S/C26H26O3/c1-25(2)11-12-26(3,4)22-15-19(9-10-21(22)25)23(27)18-7-5-17-14-20(24(28)29)8-6-16(17)13-18/h5-10,13-15H,11-12H2,1-4H3,(H,28,29) RWYREGSYPCNZTL-UHFFFAOYSA-N 31886 CD564::CHEMBL309282 Cytochrome P450 26A1 Homo sapiens 1630 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31886&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 564 2605 85240512 CHEMBL309282 DB02741 ZINC03871916 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484340 CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25) SNFYYXUGUBUECJ-UHFFFAOYSA-N 50253810 CHEMBL459505::N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)benzo[d]thiazol-2-amine::R-115866::R115866::US9963439, Talarozole Cytochrome P450 26A1 Homo sapiens 5.1 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253810&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9799888 104106249 CHEMBL459505 ZINC13675264 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484371 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)c1ccc(CCC(O)=O)cc1 InChI=1S/C24H28O3/c1-23(2)13-14-24(3,4)20-15-18(10-11-19(20)23)22(27)17-8-5-16(6-9-17)7-12-21(25)26/h5-6,8-11,15H,7,12-14H2,1-4H3,(H,25,26) YXVUTSFSLVWNLF-UHFFFAOYSA-N 50157719 CHEMBL3785624 Cytochrome P450 26A1 Homo sapiens >5000 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157719&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 117911702 340134139 CHEMBL3785624 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484373 CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(CCC(O)=O)cc1 InChI=1S/C26H32O4/c1-24(2)13-14-25(3,4)22-17-20(10-11-21(22)24)26(29-15-16-30-26)19-8-5-18(6-9-19)7-12-23(27)28/h5-6,8-11,17H,7,12-16H2,1-4H3,(H,27,28) LOBZKCODPZKVDD-UHFFFAOYSA-N 50157611 CHEMBL3787627 Cytochrome P450 26A1 Homo sapiens 340 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157611&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121472075 340134073 CHEMBL3787627 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484375 CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(\C=C\C(O)=O)cc1 InChI=1S/C26H30O4/c1-24(2)13-14-25(3,4)22-17-20(10-11-21(22)24)26(29-15-16-30-26)19-8-5-18(6-9-19)7-12-23(27)28/h5-12,17H,13-16H2,1-4H3,(H,27,28)/b12-7+ DFTYJVMZQNRUIU-KPKJPENVSA-N 50157717 CHEMBL3786581 Cytochrome P450 26A1 Homo sapiens 240 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157717&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121472072 340134137 CHEMBL3786581 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484378 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)c1cccc(CC(O)=O)c1 InChI=1S/C22H26O4S/c1-21(2)10-11-22(3,4)19-14-17(8-9-18(19)21)27(25,26)16-7-5-6-15(12-16)13-20(23)24/h5-9,12,14H,10-11,13H2,1-4H3,(H,23,24) LYYSQVHKYHHSFD-UHFFFAOYSA-N 50157728 CHEMBL3785761 Cytochrome P450 26A1 Homo sapiens >5000 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157728&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121472081 340134147 CHEMBL3785761 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484382 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)c1ccc(CC(O)=O)cc1 InChI=1S/C22H26O4S/c1-21(2)11-12-22(3,4)19-14-17(9-10-18(19)21)27(25,26)16-7-5-15(6-8-16)13-20(23)24/h5-10,14H,11-13H2,1-4H3,(H,23,24) KKSJTCFCBMZBTB-UHFFFAOYSA-N 50157730 CHEMBL3785557 Cytochrome P450 26A1 Homo sapiens >5000 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157730&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 117911715 340134149 CHEMBL3785557 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484385 CC1(C)CCC(C)(C)c2cc(Sc3cccc(CC(O)=O)c3)ccc12 InChI=1S/C22H26O2S/c1-21(2)10-11-22(3,4)19-14-17(8-9-18(19)21)25-16-7-5-6-15(12-16)13-20(23)24/h5-9,12,14H,10-11,13H2,1-4H3,(H,23,24) QAUHGDOVQAPERZ-UHFFFAOYSA-N 50157723 CHEMBL3786927 Cytochrome P450 26A1 Homo sapiens >5000 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157723&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121472085 340134143 CHEMBL3786927 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484387 CC1(C)CCC(C)(C)c2cc(Sc3ccc(CC(O)=O)cc3)ccc12 InChI=1S/C22H26O2S/c1-21(2)11-12-22(3,4)19-14-17(9-10-18(19)21)25-16-7-5-15(6-8-16)13-20(23)24/h5-10,14H,11-13H2,1-4H3,(H,23,24) BTDWGEWFAMYFFS-UHFFFAOYSA-N 50157726 CHEMBL3786043 Cytochrome P450 26A1 Homo sapiens 10600 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157726&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121472068 340134145 CHEMBL3786043 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484388 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)c1ccc(CCC(O)=O)cc1 InChI=1S/C23H28O4S/c1-22(2)13-14-23(3,4)20-15-18(10-11-19(20)22)28(26,27)17-8-5-16(6-9-17)7-12-21(24)25/h5-6,8-11,15H,7,12-14H2,1-4H3,(H,24,25) WCHWNJSOINAPDZ-UHFFFAOYSA-N 50157720 CHEMBL3786340 Cytochrome P450 26A1 Homo sapiens >5000 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157720&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121472069 340134140 CHEMBL3786340 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484391 CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc(CCC(O)=O)cc1 InChI=1S/C26H32O2S2/c1-24(2)13-14-25(3,4)22-17-20(10-11-21(22)24)26(29-15-16-30-26)19-8-5-18(6-9-19)7-12-23(27)28/h5-6,8-11,17H,7,12-16H2,1-4H3,(H,27,28) HOUMKQOYHWVXDO-UHFFFAOYSA-N 50157722 CHEMBL3787323 Cytochrome P450 26A1 Homo sapiens 270 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157722&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121472067 340134142 CHEMBL3787323 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484394 CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc(\C=C\C(O)=O)cc1 InChI=1S/C26H30O2S2/c1-24(2)13-14-25(3,4)22-17-20(10-11-21(22)24)26(29-15-16-30-26)19-8-5-18(6-9-19)7-12-23(27)28/h5-12,17H,13-16H2,1-4H3,(H,27,28)/b12-7+ XMAZZFRPGGTZPU-KPKJPENVSA-N 50157718 CHEMBL3785701 Cytochrome P450 26A1 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157718&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 90659735 340134138 CHEMBL3785701 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484400 CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc(cc1)C(O)=O InChI=1S/C24H28O2S2/c1-22(2)11-12-23(3,4)20-15-18(9-10-19(20)22)24(27-13-14-28-24)17-7-5-16(6-8-17)21(25)26/h5-10,15H,11-14H2,1-4H3,(H,25,26) NWFLPURWUQNLIV-UHFFFAOYSA-N 50033067 4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-[1,3]dithiolan-2-yl]-benzoic acid::CHEMBL323626 Cytochrome P450 26A1 Homo sapiens 1300 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033067&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 132775 103941434 CHEMBL323626 ZINC05762193 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484402 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)c1ccc(\C=C\C(O)=O)cc1 InChI=1S/C24H26O3/c1-23(2)13-14-24(3,4)20-15-18(10-11-19(20)23)22(27)17-8-5-16(6-9-17)7-12-21(25)26/h5-12,15H,13-14H2,1-4H3,(H,25,26)/b12-7+ PKXWKCWUBFDHSQ-KPKJPENVSA-N 50157608 CHEMBL95949 Cytochrome P450 26A1 Homo sapiens 4700 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157608&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 10021552 340134070 CHEMBL95949 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484417 Clc1cccc(c1)C(c1ccc2[nH]cnc2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50157605 Liarozole::Liazal::R-75251::US9963439, Liarozole Cytochrome P450 26A1 Homo sapiens 1900 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157605&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 340134067 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484419 CC1(C)CCC(C)(C)c2cc(Cc3ccc(CCC(O)=O)cc3)ccc12 InChI=1S/C24H30O2/c1-23(2)13-14-24(3,4)21-16-19(9-11-20(21)23)15-18-7-5-17(6-8-18)10-12-22(25)26/h5-9,11,16H,10,12-15H2,1-4H3,(H,25,26) WLKBQTWVLLDSGD-UHFFFAOYSA-N 50157604 CHEMBL3786324 Cytochrome P450 26A1 Homo sapiens 1660 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157604&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121472076 340134066 CHEMBL3786324 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484423 CC1(C)CCC(C)(C)c2cc(ccc12)C(\COc1ccc(cc1)C(O)=O)=N\O InChI=1S/C23H27NO4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24-27)14-28-17-8-5-15(6-9-17)21(25)26/h5-10,13,27H,11-12,14H2,1-4H3,(H,25,26)/b24-20+ JXRXCNLMYXMJBB-HIXSDJFHSA-N 50157729 CHEMBL3787691 Cytochrome P450 26A1 Homo sapiens 3500 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157729&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 127031597 340134148 CHEMBL3787691 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484427 CC1(C)CCC(C)(C)c2cc(ccc12)C(O)COc1ccc(cc1)C(O)=O InChI=1S/C23H28O4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24)14-27-17-8-5-15(6-9-17)21(25)26/h5-10,13,20,24H,11-12,14H2,1-4H3,(H,25,26) UKOIJXMXVPKISB-UHFFFAOYSA-N 50157731 CHEMBL3785511::US9963439, Compound C Cytochrome P450 26A1 Homo sapiens 2800 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157731&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 14795724 340134150 CHEMBL3785511 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484431 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)COc1ccc(cc1)C(O)=O InChI=1S/C23H26O4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24)14-27-17-8-5-15(6-9-17)21(25)26/h5-10,13H,11-12,14H2,1-4H3,(H,25,26) ZEBPEUMIMQCCQD-UHFFFAOYSA-N 50157724 CHEMBL3787564::US9963439, Compound B Cytochrome P450 26A1 Homo sapiens 4000 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157724&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 23442837 340134144 CHEMBL3787564 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484432 CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc2cc(ccc2c1)C(O)=O InChI=1S/C28H30O2S2/c1-26(2)11-12-27(3,4)24-17-22(9-10-23(24)26)28(31-13-14-32-28)21-8-7-18-15-20(25(29)30)6-5-19(18)16-21/h5-10,15-17H,11-14H2,1-4H3,(H,29,30) DPVGXUNWCVEIGT-UHFFFAOYSA-N 50157727 CHEMBL3786184 Cytochrome P450 26A1 Homo sapiens 60 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157727&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 10389639 340134146 CHEMBL3786184 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50484436 CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc2cc(ccc2c1)C(O)=O InChI=1S/C28H30O4/c1-26(2)11-12-27(3,4)24-17-22(9-10-23(24)26)28(31-13-14-32-28)21-8-7-18-15-20(25(29)30)6-5-19(18)16-21/h5-10,15-17H,11-14H2,1-4H3,(H,29,30) DOXWONJORCPBRL-UHFFFAOYSA-N 50157721 CHEMBL3786620 Cytochrome P450 26A1 Homo sapiens 110 ChEMBL 10.1021/acs.jmedchem.5b01780 10.7270/Q2J38VG8 26918322 Diaz, P; Huang, W; Keyari, CM; Buttrick, B; Price, L; Guilloteau, N; Tripathy, S; Sperandio, VG; Fronczek, FR; Astruc-Diaz, F; Isoherranen, N The University of Montana http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157721&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121474361 340134141 CHEMBL3786620 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635694 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C25H25N3O2/c1-25(2,24(29)30-3)23(28-15-14-26-17-28)19-9-11-21(12-10-19)27-22-13-8-18-6-4-5-7-20(18)16-22/h4-17,23,27H,1-3H3 MTHVGGMOKYRPIO-UHFFFAOYSA-N 50342128 3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamino)-phenyl]-propionicAcid Methyl Ester::CHEMBL1766005 Cytochrome P450 26A1 Homo sapiens 3 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342128&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 54581365 131345064 CHEMBL1766005 ZINC68153322 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635695 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3cc(OC)ccc3c2)cc1)n1ccnc1 InChI=1S/C26H27N3O3/c1-26(2,25(30)32-4)24(29-14-13-27-17-29)18-5-9-21(10-6-18)28-22-11-7-20-16-23(31-3)12-8-19(20)15-22/h5-17,24,28H,1-4H3 MUEVWLXTTJDOEB-UHFFFAOYSA-N 50342129 3-Imidazol-1-yl-3-[4-(6-methoxy-naphthalen-2-ylamino)-phenyl]-2,2-dimethyl-propionic Acid Methyl Ester::CHEMBL1766006 Cytochrome P450 26A1 Homo sapiens 8 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342129&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547333 131345065 CHEMBL1766006 ZINC71317999 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635696 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3cc(O)ccc3c2)cc1)n1ccnc1 InChI=1S/C25H25N3O3/c1-25(2,24(30)31-3)23(28-13-12-26-16-28)17-4-8-20(9-5-17)27-21-10-6-19-15-22(29)11-7-18(19)14-21/h4-16,23,27,29H,1-3H3 LEUDBINZIYAHLU-UHFFFAOYSA-N 50342130 3-[4-(6-Hydroxy-naphthalen-2-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethyl-propionic Acid Methyl Ester::CHEMBL1766007 Cytochrome P450 26A1 Homo sapiens 3 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342130&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547334 131345066 CHEMBL1766007 ZINC71329472 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635697 COC(=O)C(C)(C)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 InChI=1S/C22H22N4O3/c1-22(2,20(27)28-3)19(26-13-12-23-14-26)15-8-10-16(11-9-15)24-21-25-17-6-4-5-7-18(17)29-21/h4-14,19H,1-3H3,(H,24,25) SLBYEQHFJAGNLI-UHFFFAOYSA-N 50342131 3-[4-(Benzooxazol-2-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethylpropionicAcid Methyl Ester::CHEMBL1766008 Cytochrome P450 26A1 Homo sapiens 10 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342131&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951563 131345067 CHEMBL1766008 ZINC71315853 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635698 COC(=O)C(C)(C)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1 InChI=1S/C22H22N4O2S/c1-22(2,20(27)28-3)19(26-13-12-23-14-26)15-8-10-16(11-9-15)24-21-25-17-6-4-5-7-18(17)29-21/h4-14,19H,1-3H3,(H,24,25) UZFHIXZFZUDBGR-UHFFFAOYSA-N 50342132 3-[4-(Benzothiazol-2-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethylpropionicAcidMethyl Ester::CHEMBL1766009 Cytochrome P450 26A1 Homo sapiens 100 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342132&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951564 131345068 CHEMBL1766009 ZINC71329119 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635699 Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50176808 5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benzoimidazole::6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL389433::US9138393, Liarizole hydrochloride::US9144538, Liarizole hydrochloride::liarozole Cytochrome P450 26A1 Homo sapiens 540 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176808&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 104062424 CHEMBL389433 5210 ZINC11687637 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635700 C[C@H]([C@@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1)N(C)C InChI=1S/C21H23N5S/c1-15(25(2)3)20(26-13-12-22-14-26)16-8-10-17(11-9-16)23-21-24-18-6-4-5-7-19(18)27-21/h4-15,20H,1-3H3,(H,23,24)/t15-,20+/m1/s1 WGVPSTQRQHGEEP-QRWLVFNGSA-N 50342133 Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-imidazol-1-yl-propyl)-phenyl]-amine::CHEMBL517438::N-(4-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)phenyl)benzo[d]thiazol-2-amine::R-116010 Cytochrome P450 26A1 Homo sapiens 10 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342133&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9870337 131345069 CHEMBL517438 ZINC13911813 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635701 COC(=O)[C@@H](C)[C@H](c1ccc(Nc2ccccc2)cc1)n1ccnc1 InChI=1S/C20H21N3O2/c1-15(20(24)25-2)19(23-13-12-21-14-23)16-8-10-18(11-9-16)22-17-6-4-3-5-7-17/h3-15,19,22H,1-2H3/t15-,19+/m0/s1 ILLCEQLCOSHXQR-HNAYVOBHSA-N 50342134 CHEMBL1766010::Methyl anti-3-(1H-1-Imidazolyl)-3-[4-(phenylamino)phenyl]-2-methylpropanoate Cytochrome P450 26A1 Homo sapiens 40 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342134&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951683 131345070 CHEMBL1766010 ZINC71316933 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635702 COC(=O)[C@H](C)[C@H](c1ccc(Nc2ccccc2)cc1)n1ccnc1 InChI=1S/C20H21N3O2/c1-15(20(24)25-2)19(23-13-12-21-14-23)16-8-10-18(11-9-16)22-17-6-4-3-5-7-17/h3-15,19,22H,1-2H3/t15-,19-/m1/s1 ILLCEQLCOSHXQR-DNVCBOLYSA-N 50342135 CHEMBL1766011::Methyl syn-3-(1H-1-Imidazolyl)-3-[4-(phenylamino)phenyl]-2-methylpropanoate Cytochrome P450 26A1 Homo sapiens 26 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342135&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951684 131345071 CHEMBL1766011 ZINC71296785 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635703 COC(=O)[C@@H](C)[C@H](c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C24H23N3O2/c1-17(24(28)29-2)23(27-14-13-25-16-27)19-8-10-21(11-9-19)26-22-12-7-18-5-3-4-6-20(18)15-22/h3-17,23,26H,1-2H3/t17-,23+/m0/s1 UJBIWWFQIGDZPI-GAJHUEQPSA-N 50342136 CHEMBL1766012::Methyl anti-3-(1H-1-Imidazolyl)-3-[4-(2-naphthylamino)phenyl]-2-methylpropanoate Cytochrome P450 26A1 Homo sapiens 140 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342136&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547030 131345072 CHEMBL1766012 ZINC71316277 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635704 COC(=O)[C@H](C)[C@H](c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C24H23N3O2/c1-17(24(28)29-2)23(27-14-13-25-16-27)19-8-10-21(11-9-19)26-22-12-7-18-5-3-4-6-20(18)15-22/h3-17,23,26H,1-2H3/t17-,23-/m1/s1 UJBIWWFQIGDZPI-UZUQRXQVSA-N 50342137 CHEMBL1766013::Methyl syn-3-(1H-1-Imidazolyl)-3-[4-(2-naphthylamino)phenyl]-2-methylpropanoate Cytochrome P450 26A1 Homo sapiens 50 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342137&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547031 131345073 CHEMBL1766013 ZINC71317984 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635705 COC(=O)C(C)(C)C(c1ccc(Oc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C25H24N2O3/c1-25(2,24(28)29-3)23(27-15-14-26-17-27)19-9-11-21(12-10-19)30-22-13-8-18-6-4-5-7-20(18)16-22/h4-17,23H,1-3H3 CHHVTDCSQGINRS-UHFFFAOYSA-N 50342138 CHEMBL1766014::Methyl 3-(1H-Imidazol-1-yl)-2,3-dimethyl-3-((4-naphthalene-2-yloxy)phenyl)propanoate Cytochrome P450 26A1 Homo sapiens >1000 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342138&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547032 131345074 CHEMBL1766014 ZINC71316207 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635706 COC(=O)C(C)(C)C(c1ccc(Cc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C26H26N2O2/c1-26(2,25(29)30-3)24(28-15-14-27-18-28)22-12-8-19(9-13-22)16-20-10-11-21-6-4-5-7-23(21)17-20/h4-15,17-18,24H,16H2,1-3H3 RFDCXQLEVRXWOP-UHFFFAOYSA-N 50342139 3-Imidazol-1-yl-2,2-dimethyl-3-(4-naphthalen-2-ylmethyl-phenyl)-propionicAcid Methyl Ester::CHEMBL1766015 Cytochrome P450 26A1 Homo sapiens >1000 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342139&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951823 131345075 CHEMBL1766015 ZINC71318408 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635716 COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1 InChI=1S/C21H23N3O2/c1-21(2,20(25)26-3)19(24-14-13-22-15-24)16-9-11-18(12-10-16)23-17-7-5-4-6-8-17/h4-15,19,23H,1-3H3 XJNXEEASXBUDAQ-UHFFFAOYSA-N 50342140 3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminophenyl)-propionicAcid Methyl Ester::CHEMBL1766000 Cytochrome P450 26A1 Homo sapiens 10 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342140&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951448 131345076 CHEMBL1766000 ZINC71319187 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635717 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3OCOc3c2)cc1)n1ccnc1 InChI=1S/C22H23N3O4/c1-22(2,21(26)27-3)20(25-11-10-23-13-25)15-4-6-16(7-5-15)24-17-8-9-18-19(12-17)29-14-28-18/h4-13,20,24H,14H2,1-3H3 BKFCTFAONAURHH-UHFFFAOYSA-N 50342141 3-[4-(Benzo[1,3]dioxol-5-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethylpropionicAcid Methyl Ester::CHEMBL1766001 Cytochrome P450 26A1 Homo sapiens 8 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342141&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951561 131345077 CHEMBL1766001 ZINC71315820 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635718 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(cc2)-c2ccccc2)cc1)n1ccnc1 InChI=1S/C27H27N3O2/c1-27(2,26(31)32-3)25(30-18-17-28-19-30)22-11-15-24(16-12-22)29-23-13-9-21(10-14-23)20-7-5-4-6-8-20/h4-19,25,29H,1-3H3 ILRFXMFSDCHACY-UHFFFAOYSA-N 50342142 3-[4-(Biphenyl-4-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethyl-propionicAcid Methyl Ester::CHEMBL1766002 Cytochrome P450 26A1 Homo sapiens 250 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342142&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951562 131345078 CHEMBL1766002 ZINC71316526 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635719 COC(=O)C(C)(C)C(c1ccc(Nc2cccc3ccccc23)cc1)n1ccnc1 InChI=1S/C25H25N3O2/c1-25(2,24(29)30-3)23(28-16-15-26-17-28)19-11-13-20(14-12-19)27-22-10-6-8-18-7-4-5-9-21(18)22/h4-17,23,27H,1-3H3 LPYACPINNUETJT-UHFFFAOYSA-N 50342143 3-Imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-1-ylamino)-phenyl]-propionicAcid Methyl Ester::CHEMBL1766003 Cytochrome P450 26A1 Homo sapiens 6 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342143&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547336 131345079 CHEMBL1766003 ZINC71330272 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50635720 CCOc1ccc2ccccc2c1Nc1ccc(cc1)C(n1ccnc1)C(C)(C)C(=O)OC InChI=1S/C27H29N3O3/c1-5-33-23-15-12-19-8-6-7-9-22(19)24(23)29-21-13-10-20(11-14-21)25(30-17-16-28-18-30)27(2,3)26(31)32-4/h6-18,25,29H,5H2,1-4H3 NANFXTXUURYZJT-UHFFFAOYSA-N 50342144 3-[4-(2-Ethoxy-naphthalen-1-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethyl-propionic Acid Methyl Ester::CHEMBL1766004 Cytochrome P450 26A1 Homo sapiens 125 ChEMBL 10.1021/jm101583w 10.7270/Q2TT4R8J 21428449 Gomaa, MS; Bridgens, CE; Aboraia, AS; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342144&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547474 131345080 CHEMBL1766004 ZINC71330294 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661769 CC(C)(C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1)C(N)=O InChI=1S/C24H24N4O/c1-24(2,23(25)29)22(28-14-13-26-16-28)18-8-10-20(11-9-18)27-21-12-7-17-5-3-4-6-19(17)15-21/h3-16,22,27H,1-2H3,(H2,25,29) DHADYTVQZADBKR-UHFFFAOYSA-N 50353573 CHEMBL1828655 Cytochrome P450 26A1 Homo sapiens 50 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353573&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547187 136360259 CHEMBL1828655 ZINC72117042 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661770 CNC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C25H26N4O/c1-25(2,24(30)26-3)23(29-15-14-27-17-29)19-9-11-21(12-10-19)28-22-13-8-18-6-4-5-7-20(18)16-22/h4-17,23,28H,1-3H3,(H,26,30) CJPBDDWMTPIOHJ-UHFFFAOYSA-N 50353574 CHEMBL1831088 Cytochrome P450 26A1 Homo sapiens 12 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353574&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547331 136360260 CHEMBL1831088 ZINC72117044 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661771 CC(C)NC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C27H30N4O/c1-19(2)29-26(32)27(3,4)25(31-16-15-28-18-31)21-10-12-23(13-11-21)30-24-14-9-20-7-5-6-8-22(20)17-24/h5-19,25,30H,1-4H3,(H,29,32) VKUPJDJTVJDNPB-UHFFFAOYSA-N 50353575 CHEMBL1831089 Cytochrome P450 26A1 Homo sapiens 120 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353575&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547186 136360261 CHEMBL1831089 ZINC72116953 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661772 CN(C)C(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C26H28N4O/c1-26(2,25(31)29(3)4)24(30-16-15-27-18-30)20-10-12-22(13-11-20)28-23-14-9-19-7-5-6-8-21(19)17-23/h5-18,24,28H,1-4H3 RMMKCNRVMPRUQW-UHFFFAOYSA-N 50353576 CHEMBL1831090 Cytochrome P450 26A1 Homo sapiens 75 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353576&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547332 136360262 CHEMBL1831090 ZINC72116955 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661773 COc1ccc2cc(Nc3ccc(cc3)C(n3ccnc3)C(C)(C)CO)ccc2c1 InChI=1S/C25H27N3O2/c1-25(2,16-29)24(28-13-12-26-17-28)18-4-8-21(9-5-18)27-22-10-6-20-15-23(30-3)11-7-19(20)14-22/h4-15,17,24,27,29H,16H2,1-3H3 JTSQVNPRXLAENY-UHFFFAOYSA-N 50353577 CHEMBL1831091 Cytochrome P450 26A1 Homo sapiens 40 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353577&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547335 136360263 CHEMBL1831091 ZINC72116957 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661774 Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50176808 5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benzoimidazole::6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL389433::US9138393, Liarizole hydrochloride::US9144538, Liarizole hydrochloride::liarozole Cytochrome P450 26A1 Homo sapiens 540 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176808&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 104062424 CHEMBL389433 5210 ZINC11687637 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661775 C[C@H]([C@@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1)N(C)C InChI=1S/C21H23N5S/c1-15(25(2)3)20(26-13-12-22-14-26)16-8-10-17(11-9-16)23-21-24-18-6-4-5-7-19(18)27-21/h4-15,20H,1-3H3,(H,23,24)/t15-,20+/m1/s1 WGVPSTQRQHGEEP-QRWLVFNGSA-N 50342133 Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-imidazol-1-yl-propyl)-phenyl]-amine::CHEMBL517438::N-(4-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)phenyl)benzo[d]thiazol-2-amine::R-116010 Cytochrome P450 26A1 Homo sapiens 10 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342133&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9870337 131345069 CHEMBL517438 ZINC13911813 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661776 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1cncn1 InChI=1S/C24H24N4O2/c1-24(2,23(29)30-3)22(28-16-25-15-26-28)18-9-11-20(12-10-18)27-21-13-8-17-6-4-5-7-19(17)14-21/h4-16,22,27H,1-3H3 UXFHVEVFSFZCGS-UHFFFAOYSA-N 50353578 CHEMBL1831092 Cytochrome P450 26A1 Homo sapiens 0.35 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353578&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547033 136360264 CHEMBL1831092 ZINC68153324 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661777 CC(C)(C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1cncn1)C(O)=O InChI=1S/C23H22N4O2/c1-23(2,22(28)29)21(27-15-24-14-25-27)17-8-10-19(11-9-17)26-20-12-7-16-5-3-4-6-18(16)13-20/h3-15,21,26H,1-2H3,(H,28,29) CIPZEHKIDTWFSG-UHFFFAOYSA-N 50353579 CHEMBL1831093 Cytochrome P450 26A1 Homo sapiens >1000 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353579&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 54758311 136360265 CHEMBL1831093 ZINC72118981 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661778 CNC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1cncn1 InChI=1S/C24H25N5O/c1-24(2,23(30)25-3)22(29-16-26-15-27-29)18-9-11-20(12-10-18)28-21-13-8-17-6-4-5-7-19(17)14-21/h4-16,22,28H,1-3H3,(H,25,30) USSPWQGMEIGGND-UHFFFAOYSA-N 50353580 CHEMBL1831094 Cytochrome P450 26A1 Homo sapiens 350 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353580&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 54758312 136360266 CHEMBL1831094 ZINC72118086 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661792 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C25H25N3O2/c1-25(2,24(29)30-3)23(28-15-14-26-17-28)19-9-11-21(12-10-19)27-22-13-8-18-6-4-5-7-20(18)16-22/h4-17,23,27H,1-3H3 MTHVGGMOKYRPIO-UHFFFAOYSA-N 50342128 3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamino)-phenyl]-propionicAcid Methyl Ester::CHEMBL1766005 Cytochrome P450 26A1 Homo sapiens 3 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342128&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 54581365 131345064 CHEMBL1766005 ZINC68153322 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661793 C[C@H]([C@@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1)N(C)C InChI=1S/C21H23N5S/c1-15(25(2)3)20(26-13-12-22-14-26)16-8-10-17(11-9-16)23-21-24-18-6-4-5-7-19(18)27-21/h4-15,20H,1-3H3,(H,23,24)/t15-,20+/m1/s1 WGVPSTQRQHGEEP-QRWLVFNGSA-N 50342133 Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-imidazol-1-yl-propyl)-phenyl]-amine::CHEMBL517438::N-(4-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)phenyl)benzo[d]thiazol-2-amine::R-116010 Cytochrome P450 26A1 Homo sapiens 10 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342133&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9870337 131345069 CHEMBL517438 ZINC13911813 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661794 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1cncn1 InChI=1S/C24H24N4O2/c1-24(2,23(29)30-3)22(28-16-25-15-26-28)18-9-11-20(12-10-18)27-21-13-8-17-6-4-5-7-19(17)14-21/h4-16,22,27H,1-3H3 UXFHVEVFSFZCGS-UHFFFAOYSA-N 50353578 CHEMBL1831092 Cytochrome P450 26A1 Homo sapiens 0.3 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353578&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547033 136360264 CHEMBL1831092 ZINC68153324 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661795 N(c1ccc(cc1)C(c1ccccc1)n1ccnc1)c1ccc2ccccc2c1 InChI=1S/C26H21N3/c1-2-7-21(8-3-1)26(29-17-16-27-19-29)22-11-13-24(14-12-22)28-25-15-10-20-6-4-5-9-23(20)18-25/h1-19,26,28H DOYQKEVQXQZQNF-UHFFFAOYSA-N 50253770 CHEMBL518482::[4-(Imidazol-1-yl-phenyl-methyl)-phenyl]-naphthalen-2-yl-amine Cytochrome P450 26A1 Homo sapiens 500 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253770&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 25141344 104106213 CHEMBL518482 ZINC40865348 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661796 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C25H25N3O2/c1-25(2,24(29)30-3)23(28-15-14-26-17-28)19-9-11-21(12-10-19)27-22-13-8-18-6-4-5-7-20(18)16-22/h4-17,23,27H,1-3H3 MTHVGGMOKYRPIO-UHFFFAOYSA-N 50342128 3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamino)-phenyl]-propionicAcid Methyl Ester::CHEMBL1766005 Cytochrome P450 26A1 Homo sapiens 3 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342128&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 54581365 131345064 CHEMBL1766005 ZINC68153322 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661797 CC(C)(C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1)C(O)=O InChI=1S/C24H23N3O2/c1-24(2,23(28)29)22(27-14-13-25-16-27)18-8-10-20(11-9-18)26-21-12-7-17-5-3-4-6-19(17)15-21/h3-16,22,26H,1-2H3,(H,28,29) RTYXQMMUWJBPMQ-UHFFFAOYSA-N 50353581 CHEMBL1831082 Cytochrome P450 26A1 Homo sapiens 300 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353581&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547182 136360267 CHEMBL1831082 ZINC72118374 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661798 CCOC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C26H27N3O2/c1-4-31-25(30)26(2,3)24(29-16-15-27-18-29)20-10-12-22(13-11-20)28-23-14-9-19-7-5-6-8-21(19)17-23/h5-18,24,28H,4H2,1-3H3 GJYCFJGZPVJOKR-UHFFFAOYSA-N 50353582 CHEMBL1831083 Cytochrome P450 26A1 Homo sapiens 0.35 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353582&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547183 136360268 CHEMBL1831083 ZINC72118123 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661799 CCCCOC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C28H31N3O2/c1-4-5-18-33-27(32)28(2,3)26(31-17-16-29-20-31)22-11-13-24(14-12-22)30-25-15-10-21-8-6-7-9-23(21)19-25/h6-17,19-20,26,30H,4-5,18H2,1-3H3 PRMYIDMFDBPNTK-UHFFFAOYSA-N 50353583 CHEMBL1831084 Cytochrome P450 26A1 Homo sapiens 200 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353583&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547185 136360269 CHEMBL1831084 ZINC72118125 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661800 CCCCCOC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C29H33N3O2/c1-4-5-8-19-34-28(33)29(2,3)27(32-18-17-30-21-32)23-12-14-25(15-13-23)31-26-16-11-22-9-6-7-10-24(22)20-26/h6-7,9-18,20-21,27,31H,4-5,8,19H2,1-3H3 HWUQWWJQASMRAY-UHFFFAOYSA-N 50353584 CHEMBL1831085 Cytochrome P450 26A1 Homo sapiens 140 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353584&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547476 136360270 CHEMBL1831085 ZINC72142797 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661802 CC(C)OC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C27H29N3O2/c1-19(2)32-26(31)27(3,4)25(30-16-15-28-18-30)21-10-12-23(13-11-21)29-24-14-9-20-7-5-6-8-22(20)17-24/h5-19,25,29H,1-4H3 ARPLVMIRPYYABB-UHFFFAOYSA-N 50353585 CHEMBL1831086 Cytochrome P450 26A1 Homo sapiens 290 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353585&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547184 136360271 CHEMBL1831086 ZINC72117122 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50661803 CC(C)(C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1)C(=O)OCc1ccccc1 InChI=1S/C31H29N3O2/c1-31(2,30(35)36-21-23-8-4-3-5-9-23)29(34-19-18-32-22-34)25-13-15-27(16-14-25)33-28-17-12-24-10-6-7-11-26(24)20-28/h3-20,22,29,33H,21H2,1-2H3 GLPULBIVDYAUQN-UHFFFAOYSA-N 50353586 CHEMBL1831087 Cytochrome P450 26A1 Homo sapiens 400 ChEMBL 10.1021/jm200695m 10.7270/Q2WM1DSJ 21838328 Gomaa, MS; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353586&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44547475 136360272 CHEMBL1831087 ZINC72117040 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50852112 Clc1cccc(c1)C(N1CCN=C1)c1ccc2nc[nH]c2c1 InChI=1S/C17H15ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-5,8-11,17H,6-7H2,(H,20,21) SFRVECRHNOHBKU-UHFFFAOYSA-N 50214611 6-((3-chlorophenyl)(4,5-dihydroimidazol-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL255090 Cytochrome P450 26A1 Homo sapiens 2200 ChEMBL 10.1016/j.bmc.2007.05.046 10.7270/Q20R9Q7F 17544277 Bruno, RD; Njar, VC University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214611&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44445028 104089586 CHEMBL255090 ZINC28967359 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876733 CC(c1ccc(Nc2ccccc2)cc1)n1cncn1 InChI=1S/C16H16N4/c1-13(20-12-17-11-18-20)14-7-9-16(10-8-14)19-15-5-3-2-4-6-15/h2-13,19H,1H3 DMROGQANENHCJE-UHFFFAOYSA-N 50253709 CHEMBL461860::Phenyl-[4-(1-[1,2,4]triazol-1-yl-ethyl)-phenyl]-amine Cytochrome P450 26A1 Homo sapiens >50000 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253709&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569168 104106163 CHEMBL461860 ZINC40872808 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876734 N(c1ccccc1)c1ccc(cc1)C(c1ccccc1)n1cncn1 InChI=1S/C21H18N4/c1-3-7-17(8-4-1)21(25-16-22-15-23-25)18-11-13-20(14-12-18)24-19-9-5-2-6-10-19/h1-16,21,24H DKSITUPJKCBVEJ-UHFFFAOYSA-N 50253710 CHEMBL450523::Phenyl-[4-(phenyl-[1,2,4]triazol-1-yl-methyl)-phenyl]-amine Cytochrome P450 26A1 Homo sapiens 5000 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253710&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569169 104106164 CHEMBL450523 ZINC40845064 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876735 CC(C(c1ccc2cc(OCC(C)(C)C(O)=O)ccc2c1)n1ccnc1)N(C)C InChI=1S/C23H29N3O3/c1-16(25(4)5)21(26-11-10-24-15-26)19-7-6-18-13-20(9-8-17(18)12-19)29-14-23(2,3)22(27)28/h6-13,15-16,21H,14H2,1-5H3,(H,27,28) YLMRCYCGLCIPMC-UHFFFAOYSA-N 50162773 3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)-2,2-dimethylpropanoic acid::3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid::CHEMBL360771 Cytochrome P450 26A1 Homo sapiens 3300 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162773&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 11773824 104048888 CHEMBL360771 ZINC38363348 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876736 N(c1nc2ccccc2s1)c1ccc(cc1)C(c1ccccc1)n1ccnc1 InChI=1S/C23H18N4S/c1-2-6-17(7-3-1)22(27-15-14-24-16-27)18-10-12-19(13-11-18)25-23-26-20-8-4-5-9-21(20)28-23/h1-16,22H,(H,25,26) NYJNZWIRNUIYTC-UHFFFAOYSA-N 50253809 Benzothiazol-2-yl-{4-[(5H-imidazol-1-yl)-phenylmethyl]-phenyl}-amine::CHEMBL460780 Cytochrome P450 26A1 Homo sapiens 1500 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253809&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569222 104106248 CHEMBL460780 ZINC40862499 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876737 N(c1nc2ccccc2o1)c1ccc(cc1)C(c1ccccc1)n1ccnc1 InChI=1S/C23H18N4O/c1-2-6-17(7-3-1)22(27-15-14-24-16-27)18-10-12-19(13-11-18)25-23-26-20-8-4-5-9-21(20)28-23/h1-16,22H,(H,25,26) XLJFOZXCVNHVRH-UHFFFAOYSA-N 50253808 Benzooxazol-2-yl-{4-[(5H-imidazol-1-yl)-phenyl-methyl]-phenyl}-amine::CHEMBL518642 Cytochrome P450 26A1 Homo sapiens 900 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253808&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 16039690 104106247 CHEMBL518642 ZINC34883844 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876738 N(c1nc2ccccc2[nH]1)c1ccc(cc1)C(c1ccccc1)n1ccnc1 InChI=1S/C23H19N5/c1-2-6-17(7-3-1)22(28-15-14-24-16-28)18-10-12-19(13-11-18)25-23-26-20-8-4-5-9-21(20)27-23/h1-16,22H,(H2,25,26,27) ZZMMQVBQBSLCLI-UHFFFAOYSA-N 50253772 (1H-Benzoimidazol-2-yl)-{4-[(5H-imidazol-1-yl)-phenyl-methyl]-phenyl}-amine::CHEMBL462468 Cytochrome P450 26A1 Homo sapiens 2500 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253772&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569196 104106215 CHEMBL462468 ZINC40873293 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876739 C1Cc2ccc(Nc3ccc(cc3)C(c3ccccc3)n3ccnc3)cc2C1 InChI=1S/C25H23N3/c1-2-5-20(6-3-1)25(28-16-15-26-18-28)21-10-12-23(13-11-21)27-24-14-9-19-7-4-8-22(19)17-24/h1-3,5-6,9-18,25,27H,4,7-8H2 GVCAGSUKJPDAPR-UHFFFAOYSA-N 50253771 CHEMBL517904::[4-(Imidazol-1-yl-phenyl-methyl)-phenyl]-indan-5-yl-amine Cytochrome P450 26A1 Homo sapiens 1000 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253771&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569195 104106214 CHEMBL517904 ZINC40873073 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876740 N(c1ccc(cc1)C(c1ccccc1)n1ccnc1)c1ccc2ccccc2c1 InChI=1S/C26H21N3/c1-2-7-21(8-3-1)26(29-17-16-27-19-29)22-11-13-24(14-12-22)28-25-15-10-20-6-4-5-9-23(20)18-25/h1-19,26,28H DOYQKEVQXQZQNF-UHFFFAOYSA-N 50253770 CHEMBL518482::[4-(Imidazol-1-yl-phenyl-methyl)-phenyl]-naphthalen-2-yl-amine Cytochrome P450 26A1 Homo sapiens 500 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253770&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 25141344 104106213 CHEMBL518482 ZINC40865348 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876741 CC(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 InChI=1S/C21H19N3/c1-16(24-13-12-22-15-24)17-6-9-20(10-7-17)23-21-11-8-18-4-2-3-5-19(18)14-21/h2-16,23H,1H3 FEJYVWPFDRSJOL-UHFFFAOYSA-N 50253769 CHEMBL460130::[4-(1-Imidazol-1-yl-ethyl)-phenyl]-naphthalen-2-yl-amine Cytochrome P450 26A1 Homo sapiens 15000 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253769&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569194 104106212 CHEMBL460130 ZINC40864841 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876742 N(c1ccccc1)c1ccc(cc1)C(c1ccccc1)n1ccnc1 InChI=1S/C22H19N3/c1-3-7-18(8-4-1)22(25-16-15-23-17-25)19-11-13-21(14-12-19)24-20-9-5-2-6-10-20/h1-17,22,24H YHEUXBRFAKWNKQ-UHFFFAOYSA-N 50253768 CHEMBL459925::Phenyl-[4-(phenyl-imidazol-1-yl-methyl)-phenyl]-amine Cytochrome P450 26A1 Homo sapiens 5000 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253768&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569193 104106211 CHEMBL459925 ZINC40393810 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876743 CC(c1ccc(Nc2ccccc2)cc1)n1ccnc1 InChI=1S/C17H17N3/c1-14(20-12-11-18-13-20)15-7-9-17(10-8-15)19-16-5-3-2-4-6-16/h2-14,19H,1H3 UKUZQWGBVJLTAU-UHFFFAOYSA-N 50253711 CHEMBL449460::Phenyl-[4-(1-imidazol-1-yl-ethyl)-phenyl]-amine Cytochrome P450 26A1 Homo sapiens 35000 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253711&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569170 104106165 CHEMBL449460 ZINC40835947 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876744 c1ncn(n1)C(c1cc2ccccc2o1)c1ccc(cc1)-c1ccccc1 InChI=1S/C23H17N3O/c1-2-6-17(7-3-1)18-10-12-19(13-11-18)23(26-16-24-15-25-26)22-14-20-8-4-5-9-21(20)27-22/h1-16,23H UBVFOVYNDIFYBG-UHFFFAOYSA-N 50253850 1-(Benzofuran-2-yl-biphenyl-4-yl-methyl)-1H-[1,2,4]triazole::CHEMBL460357 Cytochrome P450 26A1 Homo sapiens 7000 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253850&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44569244 104106281 CHEMBL460357 ZINC40393423 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876745 CCc1ccc(cc1)C(c1cc2ccccc2o1)n1cncn1 InChI=1S/C19H17N3O/c1-2-14-7-9-15(10-8-14)19(22-13-20-12-21-22)18-11-16-5-3-4-6-17(16)23-18/h3-13,19H,2H2,1H3 ADSIUFOUUHJJTI-UHFFFAOYSA-N 50253849 1-(benzofuran-2-yl(4-ethylphenyl)methyl)-1H-1,2,4-triazole::CHEMBL517109 Cytochrome P450 26A1 Homo sapiens 4500 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253849&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 15950260 104106280 CHEMBL517109 ZINC34803951 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876746 Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50176808 5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benzoimidazole::6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL389433::US9138393, Liarizole hydrochloride::US9144538, Liarizole hydrochloride::liarozole Cytochrome P450 26A1 Homo sapiens 7000 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176808&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 104062424 CHEMBL389433 5210 ZINC11687637 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50876747 CCC(CC)[C@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25)/t20-/m1/s1 SNFYYXUGUBUECJ-HXUWFJFHSA-N 50377963 CHEMBL224305::R-115866 Cytochrome P450 26A1 Homo sapiens 5 ChEMBL 10.1016/j.bmc.2007.06.048 10.7270/Q2M61M5B 18722776 Gomaa, MS; Armstrong, JL; Bobillon, B; Veal, GJ; Brancale, A; Redfern, CP; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377963&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 44421596 160857046 CHEMBL224305 ZINC13675264 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954587 COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1 InChI=1S/C21H23N3O2/c1-21(2,20(25)26-3)19(24-14-13-22-15-24)16-9-11-18(12-10-16)23-17-7-5-4-6-8-17/h4-15,19,23H,1-3H3 XJNXEEASXBUDAQ-UHFFFAOYSA-N 50342140 3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminophenyl)-propionicAcid Methyl Ester::CHEMBL1766000 Cytochrome P450 26A1 Homo sapiens 10 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342140&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951448 131345076 CHEMBL1766000 ZINC71319187 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954588 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(F)cc2)cc1)n1ccnc1 InChI=1S/C21H22FN3O2/c1-21(2,20(26)27-3)19(25-13-12-23-14-25)15-4-8-17(9-5-15)24-18-10-6-16(22)7-11-18/h4-14,19,24H,1-3H3 JCSZGGFDFBJQKT-UHFFFAOYSA-N 50391716 CHEMBL2146978 Cytochrome P450 26A1 Homo sapiens 250 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391716&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71460077 163340740 CHEMBL2146978 ZINC95561126 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954589 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(cc2)[N+]([O-])=O)cc1)n1ccnc1 InChI=1S/C21H22N4O4/c1-21(2,20(26)29-3)19(24-13-12-22-14-24)15-4-6-16(7-5-15)23-17-8-10-18(11-9-17)25(27)28/h4-14,19,23H,1-3H3 YRVOVVWXWHDPBJ-UHFFFAOYSA-N 50391717 CHEMBL2146984 Cytochrome P450 26A1 Homo sapiens 100 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391717&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71454655 163340741 CHEMBL2146984 ZINC95562462 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954590 COC(=O)C(C)(C)C(c1ccc(Nc2cc(OC)c(OC)c(OC)c2)cc1)n1ccnc1 InChI=1S/C24H29N3O5/c1-24(2,23(28)32-6)22(27-12-11-25-15-27)16-7-9-17(10-8-16)26-18-13-19(29-3)21(31-5)20(14-18)30-4/h7-15,22,26H,1-6H3 SFBZZBVJJZCPGW-UHFFFAOYSA-N 50391718 CHEMBL2146985 Cytochrome P450 26A1 Homo sapiens 45 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391718&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71454656 163340742 CHEMBL2146985 ZINC95562829 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954591 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3OCOc3c2)cc1)n1ccnc1C InChI=1S/C23H25N3O4/c1-15-24-11-12-26(15)21(23(2,3)22(27)28-4)16-5-7-17(8-6-16)25-18-9-10-19-20(13-18)30-14-29-19/h5-13,21,25H,14H2,1-4H3 BPYLYOAGLRACNH-UHFFFAOYSA-N 50391719 CHEMBL2147092 Cytochrome P450 26A1 Homo sapiens >10 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391719&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71458230 163340743 CHEMBL2147092 ZINC95561639 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954592 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Cl)cc2)cc1)n1ccnc1 InChI=1S/C21H22ClN3O2/c1-21(2,20(26)27-3)19(25-13-12-23-14-25)15-4-8-17(9-5-15)24-18-10-6-16(22)7-11-18/h4-14,19,24H,1-3H3 JGIMFOWISCTLTQ-UHFFFAOYSA-N 50391720 CHEMBL2146979 Cytochrome P450 26A1 Homo sapiens 450 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391720&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71452887 163340744 CHEMBL2146979 ZINC95558838 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954593 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(C)cc2)cc1)n1ccnc1 InChI=1S/C22H25N3O2/c1-16-5-9-18(10-6-16)24-19-11-7-17(8-12-19)20(25-14-13-23-15-25)22(2,3)21(26)27-4/h5-15,20,24H,1-4H3 DZTMMWMGGGEBAA-UHFFFAOYSA-N 50391721 CHEMBL2146980 Cytochrome P450 26A1 Homo sapiens 16 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391721&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71456381 163340745 CHEMBL2146980 ZINC95558686 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954594 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(cc2)C(F)(F)F)cc1)n1ccnc1 InChI=1S/C22H22F3N3O2/c1-21(2,20(29)30-3)19(28-13-12-26-14-28)15-4-8-17(9-5-15)27-18-10-6-16(7-11-18)22(23,24)25/h4-14,19,27H,1-3H3 OHMKSXJKGQBWMU-UHFFFAOYSA-N 50391722 CHEMBL2146981 Cytochrome P450 26A1 Homo sapiens 9.4 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391722&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71452888 163340746 CHEMBL2146981 ZINC95561643 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954595 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(OC)cc2)cc1)n1ccnc1 InChI=1S/C22H25N3O3/c1-22(2,21(26)28-4)20(25-14-13-23-15-25)16-5-7-17(8-6-16)24-18-9-11-19(27-3)12-10-18/h5-15,20,24H,1-4H3 GJBWPNJVLXAJOM-UHFFFAOYSA-N 50391723 CHEMBL2146982 Cytochrome P450 26A1 Homo sapiens 700 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391723&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71460078 163340747 CHEMBL2146982 ZINC95563904 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954596 COC(=O)C(C)(C)C(c1ccc(Nc2cc(C)c(OC)c(C)c2)cc1)n1ccnc1 InChI=1S/C24H29N3O3/c1-16-13-20(14-17(2)21(16)29-5)26-19-9-7-18(8-10-19)22(27-12-11-25-15-27)24(3,4)23(28)30-6/h7-15,22,26H,1-6H3 YIOUDVTUQSYHDS-UHFFFAOYSA-N 50391724 CHEMBL2146986 Cytochrome P450 26A1 Homo sapiens 14 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391724&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71461802 163340748 CHEMBL2146986 ZINC95560081 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954597 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(cc2)C#N)cc1)n1ccnc1 InChI=1S/C22H22N4O2/c1-22(2,21(27)28-3)20(26-13-12-24-15-26)17-6-10-19(11-7-17)25-18-8-4-16(14-23)5-9-18/h4-13,15,20,25H,1-3H3 FWYKDSDFSZVULP-UHFFFAOYSA-N 50391725 CHEMBL2146983 Cytochrome P450 26A1 Homo sapiens >1000 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391725&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71460079 163340749 CHEMBL2146983 ZINC95559177 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954598 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Br)nc2)cc1)n1ccnc1 InChI=1S/C20H21BrN4O2/c1-20(2,19(26)27-3)18(25-11-10-22-13-25)14-4-6-15(7-5-14)24-16-8-9-17(21)23-12-16/h4-13,18,24H,1-3H3 JQSWLMPVRLFMRL-UHFFFAOYSA-N 50391726 CHEMBL2146987 Cytochrome P450 26A1 Homo sapiens 5.7 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391726&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71454657 163340750 CHEMBL2146987 ZINC95563912 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954599 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Br)nc2)cc1)n1cncn1 InChI=1S/C19H20BrN5O2/c1-19(2,18(26)27-3)17(25-12-21-11-23-25)13-4-6-14(7-5-13)24-15-8-9-16(20)22-10-15/h4-12,17,24H,1-3H3 KLVDMBTYFVGHGX-UHFFFAOYSA-N 50391727 CHEMBL2147089 Cytochrome P450 26A1 Homo sapiens 500 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391727&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71461812 163340751 CHEMBL2147089 ZINC95558764 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954600 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3OCOc3c2)cc1)n1ccnc1 InChI=1S/C22H23N3O4/c1-22(2,21(26)27-3)20(25-11-10-23-13-25)15-4-6-16(7-5-15)24-17-8-9-18-19(12-17)29-14-28-18/h4-13,20,24H,14H2,1-3H3 BKFCTFAONAURHH-UHFFFAOYSA-N 50342141 3-[4-(Benzo[1,3]dioxol-5-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethylpropionicAcid Methyl Ester::CHEMBL1766001 Cytochrome P450 26A1 Homo sapiens 8 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342141&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 52951561 131345077 CHEMBL1766001 ZINC71315820 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954601 COC(=O)C(C)(C)C(c1ccc(Nc2ccc3OCOc3c2)cc1)n1cncn1 InChI=1S/C21H22N4O4/c1-21(2,20(26)27-3)19(25-12-22-11-23-25)14-4-6-15(7-5-14)24-16-8-9-17-18(10-16)29-13-28-17/h4-12,19,24H,13H2,1-3H3 PZQXYXCVPHEJQB-UHFFFAOYSA-N 50391728 CHEMBL2147090 Cytochrome P450 26A1 Homo sapiens 6.7 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391728&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71461813 163340752 CHEMBL2147090 ZINC95562433 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50954602 COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1C InChI=1S/C22H25N3O2/c1-16-23-14-15-25(16)20(22(2,3)21(26)27-4)17-10-12-19(13-11-17)24-18-8-6-5-7-9-18/h5-15,20,24H,1-4H3 DAOUUETWFUNFOI-UHFFFAOYSA-N 50391729 CHEMBL2147091 Cytochrome P450 26A1 Homo sapiens 90 ChEMBL 10.1016/j.bmc.2012.08.044 10.7270/Q2D21ZQD 22989911 Gomaa, MS; Lim, AS; Lau, SC; Watts, AM; Illingworth, NA; Bridgens, CE; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391729&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71452893 163340753 CHEMBL2147091 ZINC95559702 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978504 CNC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1cncn1 InChI=1S/C20H23N5O/c1-20(2,19(26)21-3)18(25-14-22-13-23-25)15-9-11-17(12-10-15)24-16-7-5-4-6-8-16/h4-14,18,24H,1-3H3,(H,21,26) UJHBFYFGUWEEBR-UHFFFAOYSA-N 50401155 CHEMBL2205783 Cytochrome P450 26A1 Homo sapiens 1000 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401155&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71461338 163350179 CHEMBL2205783 ZINC95561768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978505 CNC(=O)C(C)(C)C(c1ccc(Nc2ccc(Cl)cc2)cc1)n1ccnc1 InChI=1S/C21H23ClN4O/c1-21(2,20(27)23-3)19(26-13-12-24-14-26)15-4-8-17(9-5-15)25-18-10-6-16(22)7-11-18/h4-14,19,25H,1-3H3,(H,23,27) UQQAUGSCZCQMBX-UHFFFAOYSA-N 50401156 CHEMBL2205782 Cytochrome P450 26A1 Homo sapiens 1000 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401156&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71459599 163350180 CHEMBL2205782 ZINC95562277 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978506 CNC(=O)C(C)(C)C(c1ccc(Nc2ccc(OC)cc2)cc1)n1ccnc1 InChI=1S/C22H26N4O2/c1-22(2,21(27)23-3)20(26-14-13-24-15-26)16-5-7-17(8-6-16)25-18-9-11-19(28-4)12-10-18/h5-15,20,25H,1-4H3,(H,23,27) RVVFDYIKSLZLNR-UHFFFAOYSA-N 50401157 CHEMBL2205781 Cytochrome P450 26A1 Homo sapiens >1000 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401157&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71450543 163350181 CHEMBL2205781 ZINC95562533 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978507 CCNC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1 InChI=1S/C22H26N4O/c1-4-24-21(27)22(2,3)20(26-15-14-23-16-26)17-10-12-19(13-11-17)25-18-8-6-5-7-9-18/h5-16,20,25H,4H2,1-3H3,(H,24,27) YQROPEFKPYTAAN-UHFFFAOYSA-N 50401158 CHEMBL2205780 Cytochrome P450 26A1 Homo sapiens 250 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401158&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71459598 163350182 CHEMBL2205780 ZINC95559938 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978508 CNC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1 InChI=1S/C21H24N4O/c1-21(2,20(26)22-3)19(25-14-13-23-15-25)16-9-11-18(12-10-16)24-17-7-5-4-6-8-17/h4-15,19,24H,1-3H3,(H,22,26) XXWMAMCGORMRNI-UHFFFAOYSA-N 50401159 CHEMBL2205779 Cytochrome P450 26A1 Homo sapiens 200 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401159&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71457689 163350183 CHEMBL2205779 ZINC95558403 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978509 CC(C)(C(c1ccc(Nc2ccc(cc2)C(O)=O)cc1)n1cncn1)C(O)=O InChI=1S/C20H20N4O4/c1-20(2,19(27)28)17(24-12-21-11-22-24)13-3-7-15(8-4-13)23-16-9-5-14(6-10-16)18(25)26/h3-12,17,23H,1-2H3,(H,25,26)(H,27,28) JDLUQANAFAMTPT-UHFFFAOYSA-N 50401160 CHEMBL2205778 Cytochrome P450 26A1 Homo sapiens 85 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401160&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71459597 163350184 CHEMBL2205778 ZINC95563014 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978510 CC(C)(C(c1ccc(Nc2ccccc2)cc1)n1ccnc1)C(O)=O InChI=1S/C20H21N3O2/c1-20(2,19(24)25)18(23-13-12-21-14-23)15-8-10-17(11-9-15)22-16-6-4-3-5-7-16/h3-14,18,22H,1-2H3,(H,24,25) KKRDUARDBIREMO-UHFFFAOYSA-N 50401161 CHEMBL2205777 Cytochrome P450 26A1 Homo sapiens >1000 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401161&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71463059 163350185 CHEMBL2205777 ZINC95560172 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978511 COC(=O)C(C)(C)C(c1ccc(Nc2ccc(cc2)C(C)=O)cc1)n1cncn1 InChI=1S/C22H24N4O3/c1-15(27)16-5-9-18(10-6-16)25-19-11-7-17(8-12-19)20(26-14-23-13-24-26)22(2,3)21(28)29-4/h5-14,20,25H,1-4H3 IIRSLIBRUAZIJO-UHFFFAOYSA-N 50401162 CHEMBL2205776 Cytochrome P450 26A1 Homo sapiens 95 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401162&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71457688 163350186 CHEMBL2205776 ZINC95561792 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 50978512 COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1cncn1 InChI=1S/C20H22N4O2/c1-20(2,19(25)26-3)18(24-14-21-13-22-24)15-9-11-17(12-10-15)23-16-7-5-4-6-8-16/h4-14,18,23H,1-3H3 RFXXESOWGZZTJX-UHFFFAOYSA-N 50401154 CHEMBL2205775 Cytochrome P450 26A1 Homo sapiens 13 ChEMBL 10.1016/j.bmc.2012.05.076 10.7270/Q2CZ3895 22727372 Gomaa, MS; Bridgens, CE; Illingworth, NA; Veal, GJ; Redfern, CP; Brancale, A; Armstrong, JL; Simons, C Cardiff University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401154&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 71463058 163350178 CHEMBL2205775 ZINC95560350 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786297 CC(=O)N1CCN(CC1)c1ccc(OCC2COC(Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3 XMAYWYJOQHXEEK-UHFFFAOYSA-N 151585 US8987315, Ketoconazole::US9180183, Ketoconazole::US9271963, Ketoconazole::US9394290, KTZ (ketoconazole)::US9963439, Ketoconazole Cytochrome P450 26A1 Homo sapiens 660 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=151585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=151585&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search KKK 3823 252825836 DB01026 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786302 CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25) SNFYYXUGUBUECJ-UHFFFAOYSA-N 50253810 CHEMBL459505::N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)benzo[d]thiazol-2-amine::R-115866::R115866::US9963439, Talarozole Cytochrome P450 26A1 Homo sapiens 5.10 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253810&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9799888 104106249 CHEMBL459505 ZINC13675264 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786307 CC(C(c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1)N(C)C InChI=1S/C21H23N5S/c1-15(25(2)3)20(26-13-12-22-14-26)16-8-10-17(11-9-16)23-21-24-18-6-4-5-7-19(18)27-21/h4-15,20H,1-3H3,(H,23,24) WGVPSTQRQHGEEP-UHFFFAOYSA-N 393281 US9963439, R116010 Cytochrome P450 26A1 Homo sapiens 4.30 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=393281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=393281&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9842708 405263409 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786312 CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(cc3)C(O)=O)ccc12 InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-16(9-10-17(18)21)23-19(24)14-5-7-15(8-6-14)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26) MUTNCGKQJGXKEM-UHFFFAOYSA-N 50061625 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid::Am 80::CHEMBL25202::Tamibarotene::US9963439, AM80::retinobenzoic acid Cytochrome P450 26A1 Homo sapiens 13050 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061625&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search A80 108143 103957180 32181 CHEMBL25202 DB04942 2648 C12864 ZINC00538415 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786314 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26) SZWKGOZKRMMLAJ-UHFFFAOYSA-N 50052414 4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene-7-carboxamido)benzoic acid::4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamido)benzoic acid::4-[(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-amino]-benzoic acid::4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid::CHEMBL69367::US9963439, AM580 Cytochrome P450 26A1 Homo sapiens 6500 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052414&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search EQN 2126 103949291 64210 CHEMBL69367 2647 C15619 ZINC03784077 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786316 C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+ FOIVPCKZDPCJJY-JQIJEIRASA-N 50032219 (E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid::4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid::4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID::4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid::4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid::4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid::CHEMBL275311::US9963439, TTNPB Cytochrome P450 26A1 Homo sapiens 5600 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032219&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search TTB 5289501 103940769 75261 CHEMBL275311 DB02877 2646 C15634 ZINC04475360 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786318 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)COc1ccc(cc1)C(O)=O InChI=1S/C23H26O4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24)14-27-17-8-5-15(6-9-17)21(25)26/h5-10,13H,11-12,14H2,1-4H3,(H,25,26) ZEBPEUMIMQCCQD-UHFFFAOYSA-N 50157724 CHEMBL3787564::US9963439, Compound B Cytochrome P450 26A1 Homo sapiens 4400 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157724&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 23442837 340134144 CHEMBL3787564 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786320 CC1(C)CCC(C)(C)c2cc(ccc12)C(O)COc1ccc(cc1)C(O)=O InChI=1S/C23H28O4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24)14-27-17-8-5-15(6-9-17)21(25)26/h5-10,13,20,24H,11-12,14H2,1-4H3,(H,25,26) UKOIJXMXVPKISB-UHFFFAOYSA-N 50157731 CHEMBL3785511::US9963439, Compound C Cytochrome P450 26A1 Homo sapiens 3250 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157731&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 14795724 340134150 CHEMBL3785511 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786322 CC1(C)CCC(C)(C)c2cc(ccc12)C(\COc1ccc(cc1)C(O)=O)=N/O InChI=1S/C23H27NO4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24-27)14-28-17-8-5-15(6-9-17)21(25)26/h5-10,13,27H,11-12,14H2,1-4H3,(H,25,26)/b24-20- JXRXCNLMYXMJBB-GFMRDNFCSA-N 393287 US9963439, Compound D Cytochrome P450 26A1 Homo sapiens 3900 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=393287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=393287&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121474357 405263415 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786324 CC1(C)C(=O)C(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O InChI=1S/C21H21NO4/c1-20(2)15-10-7-13(11-16(15)21(3,4)19(20)26)17(23)22-14-8-5-12(6-9-14)18(24)25/h5-11H,1-4H3,(H,22,23)(H,24,25) KFBPBWUZXBYJDG-UHFFFAOYSA-N 36810 BMS753::US9963439, BMS753 Cytochrome P450 26A1 Homo sapiens 40200 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36810&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 9884820 118043377 2650 ZINC34008167 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786326 CC1(C)CCC(C)(C)c2cc(ccc12)C(O)C(=O)Nc1ccc(cc1F)C(O)=O InChI=1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29) AANFHDFOMFRLLR-UHFFFAOYSA-N 393289 US9963439, BMS961 Cytochrome P450 26A1 Homo sapiens 14800 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=393289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=393289&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 2418 405263417 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786328 CC1(C)CCSc2ccc(cc12)C#Cc1ccc(cn1)C(O)=O InChI=1S/C19H17NO2S/c1-19(2)9-10-23-17-8-4-13(11-16(17)19)3-6-15-7-5-14(12-20-15)18(21)22/h4-5,7-8,11-12H,9-10H2,1-2H3,(H,21,22) IQIBKLWBVJPOQO-UHFFFAOYSA-N 393290 DDBEP::US9963439, Tazarotenic acid Cytochrome P450 26A1 Homo sapiens 7600 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=393290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=393290&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 147525 405263418 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786330 CC1(C)CCC(C)(C)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O InChI=1S/C23H24O2/c1-22(2)13-14-23(3,4)20-15-17(9-12-19(20)22)6-5-16-7-10-18(11-8-16)21(24)25/h7-12,15H,13-14H2,1-4H3,(H,24,25) OQVLOWLEEHYBJH-UHFFFAOYSA-N 50265920 4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethynyl)benzoic acid::CHEMBL451835::US9963439, BE23 Cytochrome P450 26A1 Homo sapiens 10500 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265920&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 10314719 104113501 CHEMBL451835 ZINC38493164 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786334 COC(=O)c1ccc(OC\C(=N\O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 InChI=1S/C24H29NO4/c1-23(2)12-13-24(3,4)20-14-17(8-11-19(20)23)21(25-27)15-29-18-9-6-16(7-10-18)22(26)28-5/h6-11,14,27H,12-13,15H2,1-5H3/b25-21- CVEQNBQUDVAPCP-DAFNUICNSA-N 393294 US9963439, Compound E Cytochrome P450 26A1 Homo sapiens 42500 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=393294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=393294&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121474359 405263422 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786336 COC(=O)c1ccc(OC\C(=N/O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 InChI=1S/C24H29NO4/c1-23(2)12-13-24(3,4)20-14-17(8-11-19(20)23)21(25-27)15-29-18-9-6-16(7-10-18)22(26)28-5/h6-11,14,27H,12-13,15H2,1-5H3/b25-21+ CVEQNBQUDVAPCP-NJNXFGOHSA-N 393295 US9963439, Compound F Cytochrome P450 26A1 Homo sapiens 9900 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=393295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=393295&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 121474360 405263423 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 786292 Clc1cccc(c1)C(c1ccc2[nH]cnc2c1)n1ccnc1 InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) UGFHIPBXIWJXNA-UHFFFAOYSA-N 50157605 Liarozole::Liazal::R-75251::US9963439, Liarozole Cytochrome P450 26A1 Homo sapiens 1900 US Patent 10.7270/Q2FN18J2 aid1798935 US9963439 Diaz, P; Isoherranen, N; Buttrick, B; Guilloteau, N University of Washington Through its Center for Commercialization http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157605&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 60652 340134067 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987207 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C23H27NO3/c1-22(2)11-12-23(3,4)19-14-16(7-10-18(19)22)21(27)24-17-8-5-15(6-9-17)13-20(25)26/h5-10,14H,11-13H2,1-4H3,(H,24,27)(H,25,26) ODPBIQUIOHBTDV-UHFFFAOYSA-N 476173 US10874634, Cmpd No. 01::US11364220, Compound 01 Cytochrome P450 26A1 Homo sapiens 5660 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476173&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466399 442076238 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987209 Cc1cc2c(cc1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C24H29NO3/c1-15-12-19-20(24(4,5)11-10-23(19,2)3)14-18(15)22(28)25-17-8-6-16(7-9-17)13-21(26)27/h6-9,12,14H,10-11,13H2,1-5H3,(H,25,28)(H,26,27) JMZYNBUVJDFSGB-UHFFFAOYSA-N 476180 US10874634, Cmpd No. 02::US11364220, Compound 02 Cytochrome P450 26A1 Homo sapiens 830 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476180&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466386 442076245 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987211 CN(C(=O)c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(CC(O)=O)cc1 InChI=1S/C24H29NO3/c1-23(2)12-13-24(3,4)20-15-17(8-11-19(20)23)22(28)25(5)18-9-6-16(7-10-18)14-21(26)27/h6-11,15H,12-14H2,1-5H3,(H,26,27) DNZOCGPPYZRCCL-UHFFFAOYSA-N 476181 US10874634, Cmpd No. 03::US11364220, Compound 03 Cytochrome P450 26A1 Homo sapiens >100000 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476181&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466392 442076246 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987213 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C22H27NO4S/c1-21(2)11-12-22(3,4)19-14-17(9-10-18(19)21)28(26,27)23-16-7-5-15(6-8-16)13-20(24)25/h5-10,14,23H,11-13H2,1-4H3,(H,24,25) ADFXMHUZBYRNCY-UHFFFAOYSA-N 476217 US10874634, Cmpd No. 04::US11364220, Compound 04 Cytochrome P450 26A1 Homo sapiens 1140 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476217&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023130 442076282 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987215 COC(=C)Cc1ccc(NS(=O)(=O)C2=CC3C(C=C2)C(C)(C)CCC3(C)C)cc1 InChI=1S/C24H33NO3S/c1-17(28-6)15-18-7-9-19(10-8-18)25-29(26,27)20-11-12-21-22(16-20)24(4,5)14-13-23(21,2)3/h7-12,16,21-22,25H,1,13-15H2,2-6H3 ZLOGDWADCUQKSO-UHFFFAOYSA-N 476218 US10874634, Cmpd No. 04A Cytochrome P450 26A1 Homo sapiens 14020 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476218&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155439684 442076283 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987216 COC(C)Cc1ccc(NS(=O)(=O)C2=CC3C(C=C2Br)C(C)(C)CCC3(C)C)cc1 InChI=1S/C24H34BrNO3S/c1-16(29-6)13-17-7-9-18(10-8-17)26-30(27,28)22-15-20-19(14-21(22)25)23(2,3)11-12-24(20,4)5/h7-10,14-16,19-20,26H,11-13H2,1-6H3 KTKWRYFUVKVPFK-UHFFFAOYSA-N 476221 US10874634, Cmpd No. 04B Cytochrome P450 26A1 Homo sapiens 8240 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476221&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155439724 442076286 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987217 CC1(C)CCOc2ccc(cc12)C(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C20H21NO4/c1-20(2)9-10-25-17-8-5-14(12-16(17)20)19(24)21-15-6-3-13(4-7-15)11-18(22)23/h3-8,12H,9-11H2,1-2H3,(H,21,24)(H,22,23) IFSFFTHMHWROPR-UHFFFAOYSA-N 476222 US10874634, Cmpd No. 05::US11364220, Compound 05 Cytochrome P450 26A1 Homo sapiens 39730 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476222&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155439723 442076287 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987219 CC(C)c1cc2c(cc1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C26H33NO3/c1-16(2)19-14-21-22(26(5,6)12-11-25(21,3)4)15-20(19)24(30)27-18-9-7-17(8-10-18)13-23(28)29/h7-10,14-16H,11-13H2,1-6H3,(H,27,30)(H,28,29) JIIFGCACSOMDSE-UHFFFAOYSA-N 476223 US10874634, Cmpd No. 06::US11364220, Compound 06 Cytochrome P450 26A1 Homo sapiens 1290 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476223&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466402 442076288 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987221 Cc1cc2c(cc1S(=O)(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C23H29NO4S/c1-15-12-18-19(23(4,5)11-10-22(18,2)3)14-20(15)29(27,28)24-17-8-6-16(7-9-17)13-21(25)26/h6-9,12,14,24H,10-11,13H2,1-5H3,(H,25,26) GSEBCTNOLAZZCR-UHFFFAOYSA-N 476224 US10874634, Cmpd No. 07::US11364220, Compound 07 Cytochrome P450 26A1 Homo sapiens 470 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476224&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023131 442076289 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987223 CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(CC(O)=O)cc3)ccc12 InChI=1S/C23H27NO3/c1-22(2)11-12-23(3,4)19-14-17(9-10-18(19)22)24-21(27)16-7-5-15(6-8-16)13-20(25)26/h5-10,14H,11-13H2,1-4H3,(H,24,27)(H,25,26) PHTAURFTKFFJNK-UHFFFAOYSA-N 476225 US10874634, Cmpd No. 08::US11364220, Compound 08 Cytochrome P450 26A1 Homo sapiens 3170 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476225&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 54189854 442076290 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987225 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(CC(O)=O)c(F)c1 InChI=1S/C22H26FNO4S/c1-21(2)9-10-22(3,4)18-13-16(7-8-17(18)21)29(27,28)24-15-6-5-14(11-20(25)26)19(23)12-15/h5-8,12-13,24H,9-11H2,1-4H3,(H,25,26) WLQSNHZOLRYYIR-UHFFFAOYSA-N 476226 US10874634, Cmpd No. 09::US11364220, Compound 09 Cytochrome P450 26A1 Homo sapiens 2200 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476226&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 142373055 442076291 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987227 COC(=C)Cc1ccc(NS(=O)(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1F InChI=1S/C24H30FNO3S/c1-16(29-6)13-17-7-8-18(14-22(17)25)26-30(27,28)19-9-10-20-21(15-19)24(4,5)12-11-23(20,2)3/h7-10,14-15,26H,1,11-13H2,2-6H3 VDQFKLSPLUAFES-UHFFFAOYSA-N 476227 US10874634, Cmpd No. 09A::US11364220, Compound 09A Cytochrome P450 26A1 Homo sapiens 80520 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476227&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155439683 442076292 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987228 Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C25H31NO3/c1-15-13-19-22(25(5,6)12-11-24(19,3)4)16(2)21(15)23(29)26-18-9-7-17(8-10-18)14-20(27)28/h7-10,13H,11-12,14H2,1-6H3,(H,26,29)(H,27,28) QWFCVDPZBKASNN-UHFFFAOYSA-N 476228 US10874634, Cmpd No. 10::US11364220, Compound 10 Cytochrome P450 26A1 Homo sapiens 8230 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476228&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466401 442076293 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987230 CC(C)c1cc(c(cc1S(=O)(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)C)C(C)(C)C InChI=1S/C25H35NO4S/c1-16(2)19-14-20(24(3,4)5)21(25(6,7)8)15-22(19)31(29,30)26-18-11-9-17(10-12-18)13-23(27)28/h9-12,14-16,26H,13H2,1-8H3,(H,27,28) JBJXOYDMLQZJEZ-UHFFFAOYSA-N 476229 US10874634, Cmpd No. 11 Cytochrome P450 26A1 Homo sapiens 20010 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476229&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023132 442076294 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987232 Cc1cc2c(cc1S(=O)(=O)Nc1ccc(cc1)C(C)(C)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C25H33NO4S/c1-16-14-19-20(24(4,5)13-12-23(19,2)3)15-21(16)31(29,30)26-18-10-8-17(9-11-18)25(6,7)22(27)28/h8-11,14-15,26H,12-13H2,1-7H3,(H,27,28) UHZPCSOSOBBICN-UHFFFAOYSA-N 476230 US10874634, Cmpd No. 12::US11364220, Compound 12 Cytochrome P450 26A1 Homo sapiens 100.0 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476230&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155439709 442076295 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987234 Cc1cc2c(cc1S(=O)(=O)Nc1ccc(cc1)C1(CC1)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C25H31NO4S/c1-16-14-19-20(24(4,5)11-10-23(19,2)3)15-21(16)31(29,30)26-18-8-6-17(7-9-18)25(12-13-25)22(27)28/h6-9,14-15,26H,10-13H2,1-5H3,(H,27,28) WUVJBECPVPHXJV-UHFFFAOYSA-N 476231 US10874634, Cmpd No. 13::US11364220, Compound 13 Cytochrome P450 26A1 Homo sapiens 6200 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476231&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023133 442076296 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987236 Cc1cc2c(cc1S(=O)(=O)Nc1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C22H27NO4S/c1-14-12-17-18(22(4,5)11-10-21(17,2)3)13-19(14)28(26,27)23-16-8-6-15(7-9-16)20(24)25/h6-9,12-13,23H,10-11H2,1-5H3,(H,24,25) KLRZNKUKHCTOQI-UHFFFAOYSA-N 476232 US10874634, Cmpd No. 14::US11364220, Compound 14 Cytochrome P450 26A1 Homo sapiens 28390 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476232&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 135132373 442076297 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987238 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(cc1)C(O)=O InChI=1S/C21H25NO4S/c1-20(2)11-12-21(3,4)18-13-16(9-10-17(18)20)27(25,26)22-15-7-5-14(6-8-15)19(23)24/h5-10,13,22H,11-12H2,1-4H3,(H,23,24) OZQUYPOBYXOMHP-UHFFFAOYSA-N 476233 US10874634, Cmpd No. 15::US11364220, Compound 15 Cytochrome P450 26A1 Homo sapiens >1000000 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476233&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 129723241 442076298 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987240 Cc1cc2c(cc1C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C26H33NO3/c1-16-14-20-21(25(4,5)13-12-24(20,2)3)15-19(16)22(28)27-18-10-8-17(9-11-18)26(6,7)23(29)30/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)(H,29,30) IWLKEDJGBSECTH-UHFFFAOYSA-N 476234 US10874634, Cmpd No. 16::US11364220, Compound 16 Cytochrome P450 26A1 Homo sapiens 1774 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476234&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466393 442076299 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987242 CCC(CC)(C(O)=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 InChI=1S/C26H35NO4S/c1-7-26(8-2,23(28)29)18-9-11-19(12-10-18)27-32(30,31)20-13-14-21-22(17-20)25(5,6)16-15-24(21,3)4/h9-14,17,27H,7-8,15-16H2,1-6H3,(H,28,29) YICMNMYTJJNEQA-UHFFFAOYSA-N 476235 US10874634, Cmpd No. 17::US11364220, Compound 17 Cytochrome P450 26A1 Homo sapiens 38660 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476235&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 149362087 442076300 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987244 CCC(CC)(C(O)=O)c1ccc(NS(=O)(=O)c2cc3c(cc2C)C(C)(C)CCC3(C)C)cc1 InChI=1S/C27H37NO4S/c1-8-27(9-2,24(29)30)19-10-12-20(13-11-19)28-33(31,32)23-17-22-21(16-18(23)3)25(4,5)14-15-26(22,6)7/h10-13,16-17,28H,8-9,14-15H2,1-7H3,(H,29,30) NXQREWXHBBIHHU-UHFFFAOYSA-N 476236 US10874634, Cmpd No. 18::US11364220, Compound 18 Cytochrome P450 26A1 Homo sapiens >1000000 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476236&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466398 442076301 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987246 CC(C)C(C(O)=O)c1ccc(NS(=O)(=O)c2cc3c(cc2C)C(C)(C)CCC3(C)C)cc1 InChI=1S/C26H35NO4S/c1-16(2)23(24(28)29)18-8-10-19(11-9-18)27-32(30,31)22-15-21-20(14-17(22)3)25(4,5)12-13-26(21,6)7/h8-11,14-16,23,27H,12-13H2,1-7H3,(H,28,29) NJFQFQKDVLAUCN-UHFFFAOYSA-N 476237 US10874634, Cmpd No. 19::US11364220, Compound 19 Cytochrome P450 26A1 Homo sapiens 741 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476237&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 148636800 442076302 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 987248 Cc1ccc(NS(=O)(=O)c2cc(C)c3OC(C)(C)CC(C)(C)c3c2)cc1 InChI=1S/C21H27NO3S/c1-14-7-9-16(10-8-14)22-26(23,24)17-11-15(2)19-18(12-17)20(3,4)13-21(5,6)25-19/h7-12,22H,13H2,1-6H3 LWTRGDGFHYLSHT-UHFFFAOYSA-N 476238 US10874634, Cmpd No. 21::US11364220, Compound 21 Cytochrome P450 26A1 Homo sapiens 1900 US Patent 10.7270/Q2Q52SP3 aid1805109 US10874634 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476238&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023134 442076303 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177178 CC(C)(C)c1cccc(c1)C(=O)Cc1ccc(\C=C\C(O)=O)cc1 InChI=1S/C21H22O3/c1-21(2,3)18-6-4-5-17(14-18)19(22)13-16-9-7-15(8-10-16)11-12-20(23)24/h4-12,14H,13H2,1-3H3,(H,23,24)/b12-11+ HFQDVQRBKABEQK-VAWYXSNFSA-N 557291 US11358933, Compound 025 Cytochrome P450 26A1 Homo sapiens 45600 US Patent 10.7270/Q2CC13XJ aid1806596 US11358933 Cameron, DA; Petkovich, M; Saha, U Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557291&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155329348 471698001 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177180 CC(C)(C)c1cccc(c1)-c1cc2cc(\C=C\C(O)=O)ccc2[nH]1 InChI=1S/C21H21NO2/c1-21(2,3)17-6-4-5-15(12-17)19-13-16-11-14(8-10-20(23)24)7-9-18(16)22-19/h4-13,22H,1-3H3,(H,23,24)/b10-8+ VEHXAGUYCZGFMR-CSKARUKUSA-N 557292 US11358933, Compound 026 Cytochrome P450 26A1 Homo sapiens 7000 US Patent 10.7270/Q2CC13XJ aid1806596 US11358933 Cameron, DA; Petkovich, M; Saha, U Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557292&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155329422 471698002 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177182 CC1(C)CC(C)(C)c2cc(cc(CC=C)c2O1)C(=O)Cc1ccc(CC(O)=O)cc1 InChI=1S/C26H30O4/c1-6-7-19-14-20(15-21-24(19)30-26(4,5)16-25(21,2)3)22(27)12-17-8-10-18(11-9-17)13-23(28)29/h6,8-11,14-15H,1,7,12-13,16H2,2-5H3,(H,28,29) SBDIUBHXYLNXDZ-UHFFFAOYSA-N 557293 US11358933, Compound 027 Cytochrome P450 26A1 Homo sapiens 8600 US Patent 10.7270/Q2CC13XJ aid1806596 US11358933 Cameron, DA; Petkovich, M; Saha, U Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557293&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155329344 471698003 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177184 CC1(C)CC(C)(C)c2cc(cc(C3CC3)c2O1)C(=O)Cc1ccc(CC(O)=O)cc1 InChI=1S/C26H30O4/c1-25(2)15-26(3,4)30-24-20(18-9-10-18)13-19(14-21(24)25)22(27)11-16-5-7-17(8-6-16)12-23(28)29/h5-8,13-14,18H,9-12,15H2,1-4H3,(H,28,29) OXAQEMCAWCHBNY-UHFFFAOYSA-N 557294 US11358933, Compound 028 Cytochrome P450 26A1 Homo sapiens >1000000 US Patent 10.7270/Q2CC13XJ aid1806596 US11358933 Cameron, DA; Petkovich, M; Saha, U Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557294&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155329423 471698004 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177187 CC1(C)CC(C)(C)c2cc(cc(C3CC3)c2O1)B1Oc2ccc(CC(O)=O)cc2O1 InChI=1S/C24H27BO5/c1-23(2)13-24(3,4)28-22-17(15-6-7-15)11-16(12-18(22)23)25-29-19-8-5-14(10-21(26)27)9-20(19)30-25/h5,8-9,11-12,15H,6-7,10,13H2,1-4H3,(H,26,27) ZYOUUXOQSIHVQK-UHFFFAOYSA-N 557296 US11358933, Compound 030 Cytochrome P450 26A1 Homo sapiens 31500 US Patent 10.7270/Q2CC13XJ aid1806596 US11358933 Cameron, DA; Petkovich, M; Saha, U Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557296&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155643145 471698006 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177190 CC(C)(C)c1cccc(c1)-c1cc2cc(CC(O)=O)ccc2o1 InChI=1S/C20H20O3/c1-20(2,3)16-6-4-5-14(11-16)18-12-15-9-13(10-19(21)22)7-8-17(15)23-18/h4-9,11-12H,10H2,1-3H3,(H,21,22) WSVICOXPZMMORR-UHFFFAOYSA-N 557298 US11358933, Compound 032 Cytochrome P450 26A1 Homo sapiens 8600 US Patent 10.7270/Q2CC13XJ aid1806596 US11358933 Cameron, DA; Petkovich, M; Saha, U Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557298&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155329337 471698008 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177192 Cc1ccc(cc1-c1cc2cc(\C=C\C(O)=O)ccc2[nH]1)C(C)(C)C InChI=1S/C22H23NO2/c1-14-5-8-17(22(2,3)4)13-18(14)20-12-16-11-15(7-10-21(24)25)6-9-19(16)23-20/h5-13,23H,1-4H3,(H,24,25)/b10-7+ RGDCBTDUOQXZBC-JXMROGBWSA-N 557299 US11358933, Compound 034 Cytochrome P450 26A1 Homo sapiens 9600 US Patent 10.7270/Q2CC13XJ aid1806596 US11358933 Cameron, DA; Petkovich, M; Saha, U Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557299&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155329426 471698009 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177374 CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C23H27NO3/c1-22(2)11-12-23(3,4)19-14-16(7-10-18(19)22)21(27)24-17-8-5-15(6-9-17)13-20(25)26/h5-10,14H,11-13H2,1-4H3,(H,24,27)(H,25,26) ODPBIQUIOHBTDV-UHFFFAOYSA-N 476173 US10874634, Cmpd No. 01::US11364220, Compound 01 Cytochrome P450 26A1 Homo sapiens 5660 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476173&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466399 442076238 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177376 Cc1cc2c(cc1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C24H29NO3/c1-15-12-19-20(24(4,5)11-10-23(19,2)3)14-18(15)22(28)25-17-8-6-16(7-9-17)13-21(26)27/h6-9,12,14H,10-11,13H2,1-5H3,(H,25,28)(H,26,27) JMZYNBUVJDFSGB-UHFFFAOYSA-N 476180 US10874634, Cmpd No. 02::US11364220, Compound 02 Cytochrome P450 26A1 Homo sapiens 830 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476180&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466386 442076245 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177378 CN(C(=O)c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(CC(O)=O)cc1 InChI=1S/C24H29NO3/c1-23(2)12-13-24(3,4)20-15-17(8-11-19(20)23)22(28)25(5)18-9-6-16(7-10-18)14-21(26)27/h6-11,15H,12-14H2,1-5H3,(H,26,27) DNZOCGPPYZRCCL-UHFFFAOYSA-N 476181 US10874634, Cmpd No. 03::US11364220, Compound 03 Cytochrome P450 26A1 Homo sapiens >100000 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476181&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466392 442076246 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177380 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C22H27NO4S/c1-21(2)11-12-22(3,4)19-14-17(9-10-18(19)21)28(26,27)23-16-7-5-15(6-8-16)13-20(24)25/h5-10,14,23H,11-13H2,1-4H3,(H,24,25) ADFXMHUZBYRNCY-UHFFFAOYSA-N 476217 US10874634, Cmpd No. 04::US11364220, Compound 04 Cytochrome P450 26A1 Homo sapiens 1140 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476217&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023130 442076282 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177382 COC(=C)Cc1ccc(NS(=O)(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 InChI=1S/C24H31NO3S/c1-17(28-6)15-18-7-9-19(10-8-18)25-29(26,27)20-11-12-21-22(16-20)24(4,5)14-13-23(21,2)3/h7-12,16,25H,1,13-15H2,2-6H3 ADKOTZSOXBQRGU-UHFFFAOYSA-N 557708 US11364220, Compound 04A Cytochrome P450 26A1 Homo sapiens 14020 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557708&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 157079946 471698411 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177383 COC(=C)Cc1ccc(NS(=O)(=O)c2cc3c(cc2Br)C(C)(C)CCC3(C)C)cc1 InChI=1S/C24H30BrNO3S/c1-16(29-6)13-17-7-9-18(10-8-17)26-30(27,28)22-15-20-19(14-21(22)25)23(2,3)11-12-24(20,4)5/h7-10,14-15,26H,1,11-13H2,2-6H3 IAOQEZWNOMPTPT-UHFFFAOYSA-N 557709 US11364220, Compound 04B Cytochrome P450 26A1 Homo sapiens 8240 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557709&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 158642610 471698412 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177384 CC1(C)CCOc2ccc(cc12)C(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C20H21NO4/c1-20(2)9-10-25-17-8-5-14(12-16(17)20)19(24)21-15-6-3-13(4-7-15)11-18(22)23/h3-8,12H,9-11H2,1-2H3,(H,21,24)(H,22,23) IFSFFTHMHWROPR-UHFFFAOYSA-N 476222 US10874634, Cmpd No. 05::US11364220, Compound 05 Cytochrome P450 26A1 Homo sapiens 39730 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476222&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155439723 442076287 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177386 CC(C)c1cc2c(cc1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C26H33NO3/c1-16(2)19-14-21-22(26(5,6)12-11-25(21,3)4)15-20(19)24(30)27-18-9-7-17(8-10-18)13-23(28)29/h7-10,14-16H,11-13H2,1-6H3,(H,27,30)(H,28,29) JIIFGCACSOMDSE-UHFFFAOYSA-N 476223 US10874634, Cmpd No. 06::US11364220, Compound 06 Cytochrome P450 26A1 Homo sapiens 1290 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476223&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466402 442076288 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177388 Cc1cc2c(cc1S(=O)(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C23H29NO4S/c1-15-12-18-19(23(4,5)11-10-22(18,2)3)14-20(15)29(27,28)24-17-8-6-16(7-9-17)13-21(25)26/h6-9,12,14,24H,10-11,13H2,1-5H3,(H,25,26) GSEBCTNOLAZZCR-UHFFFAOYSA-N 476224 US10874634, Cmpd No. 07::US11364220, Compound 07 Cytochrome P450 26A1 Homo sapiens 470 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476224&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023131 442076289 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177390 CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(CC(O)=O)cc3)ccc12 InChI=1S/C23H27NO3/c1-22(2)11-12-23(3,4)19-14-17(9-10-18(19)22)24-21(27)16-7-5-15(6-8-16)13-20(25)26/h5-10,14H,11-13H2,1-4H3,(H,24,27)(H,25,26) PHTAURFTKFFJNK-UHFFFAOYSA-N 476225 US10874634, Cmpd No. 08::US11364220, Compound 08 Cytochrome P450 26A1 Homo sapiens 3170 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476225&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 54189854 442076290 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177392 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(CC(O)=O)c(F)c1 InChI=1S/C22H26FNO4S/c1-21(2)9-10-22(3,4)18-13-16(7-8-17(18)21)29(27,28)24-15-6-5-14(11-20(25)26)19(23)12-15/h5-8,12-13,24H,9-11H2,1-4H3,(H,25,26) WLQSNHZOLRYYIR-UHFFFAOYSA-N 476226 US10874634, Cmpd No. 09::US11364220, Compound 09 Cytochrome P450 26A1 Homo sapiens 2200 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476226&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 142373055 442076291 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177394 COC(=C)Cc1ccc(NS(=O)(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1F InChI=1S/C24H30FNO3S/c1-16(29-6)13-17-7-8-18(14-22(17)25)26-30(27,28)19-9-10-20-21(15-19)24(4,5)12-11-23(20,2)3/h7-10,14-15,26H,1,11-13H2,2-6H3 VDQFKLSPLUAFES-UHFFFAOYSA-N 476227 US10874634, Cmpd No. 09A::US11364220, Compound 09A Cytochrome P450 26A1 Homo sapiens 80520 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476227&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155439683 442076292 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177395 Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C25H31NO3/c1-15-13-19-22(25(5,6)12-11-24(19,3)4)16(2)21(15)23(29)26-18-9-7-17(8-10-18)14-20(27)28/h7-10,13H,11-12,14H2,1-6H3,(H,26,29)(H,27,28) QWFCVDPZBKASNN-UHFFFAOYSA-N 476228 US10874634, Cmpd No. 10::US11364220, Compound 10 Cytochrome P450 26A1 Homo sapiens 8230 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476228&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466401 442076293 C03768 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177397 CC(C)c1cc2c(cc1S(=O)(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C InChI=1S/C25H33NO4S/c1-16(2)19-14-20-21(25(5,6)12-11-24(20,3)4)15-22(19)31(29,30)26-18-9-7-17(8-10-18)13-23(27)28/h7-10,14-16,26H,11-13H2,1-6H3,(H,27,28) WWWDGUXNLBPAKU-UHFFFAOYSA-N 557717 US11364220, Compound 11 Cytochrome P450 26A1 Homo sapiens 20010 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=557717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=557717&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 142373054 471698417 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177399 Cc1cc2c(cc1S(=O)(=O)Nc1ccc(cc1)C(C)(C)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C25H33NO4S/c1-16-14-19-20(24(4,5)13-12-23(19,2)3)15-21(16)31(29,30)26-18-10-8-17(9-11-18)25(6,7)22(27)28/h8-11,14-15,26H,12-13H2,1-7H3,(H,27,28) UHZPCSOSOBBICN-UHFFFAOYSA-N 476230 US10874634, Cmpd No. 12::US11364220, Compound 12 Cytochrome P450 26A1 Homo sapiens 100.0 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476230&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 155439709 442076295 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177401 Cc1cc2c(cc1S(=O)(=O)Nc1ccc(cc1)C1(CC1)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C25H31NO4S/c1-16-14-19-20(24(4,5)11-10-23(19,2)3)15-21(16)31(29,30)26-18-8-6-17(7-9-18)25(12-13-25)22(27)28/h6-9,14-15,26H,10-13H2,1-5H3,(H,27,28) WUVJBECPVPHXJV-UHFFFAOYSA-N 476231 US10874634, Cmpd No. 13::US11364220, Compound 13 Cytochrome P450 26A1 Homo sapiens 6200 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476231&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023133 442076296 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177403 Cc1cc2c(cc1S(=O)(=O)Nc1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C22H27NO4S/c1-14-12-17-18(22(4,5)11-10-21(17,2)3)13-19(14)28(26,27)23-16-8-6-15(7-9-16)20(24)25/h6-9,12-13,23H,10-11H2,1-5H3,(H,24,25) KLRZNKUKHCTOQI-UHFFFAOYSA-N 476232 US10874634, Cmpd No. 14::US11364220, Compound 14 Cytochrome P450 26A1 Homo sapiens 28390 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476232&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 135132373 442076297 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177405 CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(cc1)C(O)=O InChI=1S/C21H25NO4S/c1-20(2)11-12-21(3,4)18-13-16(9-10-17(18)20)27(25,26)22-15-7-5-14(6-8-15)19(23)24/h5-10,13,22H,11-12H2,1-4H3,(H,23,24) OZQUYPOBYXOMHP-UHFFFAOYSA-N 476233 US10874634, Cmpd No. 15::US11364220, Compound 15 Cytochrome P450 26A1 Homo sapiens >1000000 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476233&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 129723241 442076298 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177407 Cc1cc2c(cc1C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C26H33NO3/c1-16-14-20-21(25(4,5)13-12-24(20,2)3)15-19(16)22(28)27-18-10-8-17(9-11-18)26(6,7)23(29)30/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)(H,29,30) IWLKEDJGBSECTH-UHFFFAOYSA-N 476234 US10874634, Cmpd No. 16::US11364220, Compound 16 Cytochrome P450 26A1 Homo sapiens 1774 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476234&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466393 442076299 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177409 CCC(CC)(C(O)=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 InChI=1S/C26H35NO4S/c1-7-26(8-2,23(28)29)18-9-11-19(12-10-18)27-32(30,31)20-13-14-21-22(17-20)25(5,6)16-15-24(21,3)4/h9-14,17,27H,7-8,15-16H2,1-6H3,(H,28,29) YICMNMYTJJNEQA-UHFFFAOYSA-N 476235 US10874634, Cmpd No. 17::US11364220, Compound 17 Cytochrome P450 26A1 Homo sapiens 38660 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476235&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 149362087 442076300 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177411 CCC(CC)(C(O)=O)c1ccc(NS(=O)(=O)c2cc3c(cc2C)C(C)(C)CCC3(C)C)cc1 InChI=1S/C27H37NO4S/c1-8-27(9-2,24(29)30)19-10-12-20(13-11-19)28-33(31,32)23-17-22-21(16-18(23)3)25(4,5)14-15-26(22,6)7/h10-13,16-17,28H,8-9,14-15H2,1-7H3,(H,29,30) NXQREWXHBBIHHU-UHFFFAOYSA-N 476236 US10874634, Cmpd No. 18::US11364220, Compound 18 Cytochrome P450 26A1 Homo sapiens >1000000 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476236&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 153466398 442076301 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177413 CC(C)C(C(O)=O)c1ccc(NS(=O)(=O)c2cc3c(cc2C)C(C)(C)CCC3(C)C)cc1 InChI=1S/C26H35NO4S/c1-16(2)23(24(28)29)18-8-10-19(11-9-18)27-32(30,31)22-15-21-20(14-17(22)3)25(4,5)12-13-26(21,6)7/h8-11,14-16,23,27H,12-13H2,1-7H3,(H,28,29) NJFQFQKDVLAUCN-UHFFFAOYSA-N 476237 US10874634, Cmpd No. 19::US11364220, Compound 19 Cytochrome P450 26A1 Homo sapiens 741 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476237&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 148636800 442076302 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0 1177415 Cc1ccc(NS(=O)(=O)c2cc(C)c3OC(C)(C)CC(C)(C)c3c2)cc1 InChI=1S/C21H27NO3S/c1-14-7-9-16(10-8-14)22-26(23,24)17-11-15(2)19-18(12-17)20(3,4)13-21(5,6)25-19/h7-12,22H,13H2,1-6H3 LWTRGDGFHYLSHT-UHFFFAOYSA-N 476238 US10874634, Cmpd No. 21::US11364220, Compound 21 Cytochrome P450 26A1 Homo sapiens 1900 US Patent 10.7270/Q2QN6B03 aid1806602 US11364220 Cameron, DA; Petkovich, M; Rantanen, TK; Snieckus, V; Board, J; Singh, S; Maheta, AJ Queen''s University at Kingston http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5100&target=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476238&enzyme=Cytochrome+P450+26A1&column=ki&startPg=0&Increment=50&submit=Search 156023134 442076303 1 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI Cytochrome P450 26A1 CP26A_HUMAN O43174 B3KNI4 Q5VXH9 Q5VXI0