BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51059258 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Homo sapiens 10.0 ChEMBL 10.1016/j.bmcl.2013.02.045 10.7270/Q2S183VK 23466228 Gao, M; Shi, Z; Wang, M; Zheng, QH Indiana University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51059261 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1016/j.bmcl.2013.02.045 10.7270/Q2S183VK 23466228 Gao, M; Shi, Z; Wang, M; Zheng, QH Indiana University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51035780 CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1cccc(=O)n1C InChI=1S/C26H30BrN5O2/c1-29-15-16(13-18-17-5-3-6-20-24(17)19(14-21(18)29)25(27)28-20)26(34)32-11-9-31(10-12-32)22-7-4-8-23(33)30(22)2/h3-8,16,18,21,28H,9-15H2,1-2H3/t16-,18-,21-/m1/s1 AWFDCTXCTHGORH-HGHGUNKESA-N 50423465 ERGOLINE D(2) dopamine receptor Homo sapiens 56 ChEMBL 10.1016/j.bmcl.2007.12.030 10.7270/Q2WQ053B 18162395 Troxler, T; Enz, A; Hoyer, D; Langenegger, D; Neumann, P; Pfaffli, P; Schoeffter, P; Hurth, K Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9849682 164152340 ZINC03936044 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51035849 CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1 InChI=1S/C26H27BrN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1 GZFMZJDVLOZLLL-OMXJDXKCSA-N 50423462 CHEMBL251835 D(2) dopamine receptor Homo sapiens 126 ChEMBL 10.1016/j.bmcl.2007.12.030 10.7270/Q2WQ053B 18162395 Troxler, T; Enz, A; Hoyer, D; Langenegger, D; Neumann, P; Pfaffli, P; Schoeffter, P; Hurth, K Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44447073 164152337 CHEMBL251835 ZINC29038760 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51078599 C(N[C@@H]1C2C3CC4C5CC(C2C35)C14)C12C3C4C5C3C1C5C24 InChI=1S/C20H23N/c1-4-5-2-6-8(4)10-7(1)9(5)19(11(6)10)21-3-20-16-13-12-14(16)18(20)15(12)17(13)20/h4-19,21H,1-3H2/t4?,5?,6?,7?,8?,9?,10?,11?,12?,13?,14?,15?,16?,17?,18?,19-,20?/m0/s1 CHZUEGVOEFMIJH-ZKRSMWHSSA-N 50440988 CHEMBL2432039 D(2) dopamine receptor Homo sapiens 5675 ChEMBL 10.1016/j.bmc.2013.07.045 10.7270/Q20P11GK 23981939 Banister, SD; Manoli, M; Barron, ML; Werry, EL; Kassiou, M The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50440988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50440988&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73355415 175453305 CHEMBL2432039 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51078600 Fc1cccc(CCCN[C@@H]2C3C4CC5C6CC(C3C46)C25)c1 InChI=1S/C20H24FN/c21-11-5-1-3-10(7-11)4-2-6-22-20-17-13-9-14-16-12(13)8-15(17)18(16)19(14)20/h1,3,5,7,12-20,22H,2,4,6,8-9H2/t12?,13?,14?,15?,16?,17?,18?,19?,20-/m0/s1 SJWCMFMHVZULSJ-DKSPCFMDSA-N 50441000 CHEMBL2432050 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2013.07.045 10.7270/Q20P11GK 23981939 Banister, SD; Manoli, M; Barron, ML; Werry, EL; Kassiou, M The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441000&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73349358 175453317 CHEMBL2432050 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51078601 C(Cc1ccccn1)N[C@@H]1C2C3CC4C5CC(C2C35)C14 InChI=1S/C18H22N2/c1-2-5-19-9(3-1)4-6-20-18-15-11-8-12-14-10(11)7-13(15)16(14)17(12)18/h1-3,5,10-18,20H,4,6-8H2/t10?,11?,12?,13?,14?,15?,16?,17?,18-/m0/s1 DUZKXKAAUHDBQA-CAUKCHDASA-N 50441001 CHEMBL2432049 D(2) dopamine receptor Homo sapiens 9906 ChEMBL 10.1016/j.bmc.2013.07.045 10.7270/Q20P11GK 23981939 Banister, SD; Manoli, M; Barron, ML; Werry, EL; Kassiou, M The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441001&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73347826 175453318 CHEMBL2432049 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51078602 C(Cc1ccccc1)N[C@@H]1C2C3CC4C5CC(C2C35)C14 InChI=1S/C19H23N/c1-2-4-10(5-3-1)6-7-20-19-16-12-9-13-15-11(12)8-14(16)17(15)18(13)19/h1-5,11-20H,6-9H2/t11?,12?,13?,14?,15?,16?,17?,18?,19-/m0/s1 KBAKPEFQDPCCTP-RAOGCBAWSA-N 50440991 CHEMBL2432048 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2013.07.045 10.7270/Q20P11GK 23981939 Banister, SD; Manoli, M; Barron, ML; Werry, EL; Kassiou, M The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50440991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50440991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73346334 175453308 CHEMBL2432048 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51078603 C(N[C@@H]1C2C3CC4C5CC(C2C35)C14)c1cccnc1 InChI=1S/C17H20N2/c1-2-8(6-18-3-1)7-19-17-14-10-5-11-13-9(10)4-12(14)15(13)16(11)17/h1-3,6,9-17,19H,4-5,7H2/t9?,10?,11?,12?,13?,14?,15?,16?,17-/m0/s1 CNPQMMDLXZBMLB-KPCGFGSOSA-N 50441002 CHEMBL2432047 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2013.07.045 10.7270/Q20P11GK 23981939 Banister, SD; Manoli, M; Barron, ML; Werry, EL; Kassiou, M The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441002&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73346333 175453319 CHEMBL2432047 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51078604 OC12C3C4C5C3C(C3C5CC4C13)N2CC1CCCCC1 InChI=1S/C18H25NO/c20-18-15-10-6-9-11-12(10)16(18)14(11)17(13(9)15)19(18)7-8-4-2-1-3-5-8/h8-17,20H,1-7H2 RRBNCHNWWUXYEM-UHFFFAOYSA-N 50401366 CHEMBL2205831 D(2) dopamine receptor Homo sapiens 2830 ChEMBL 10.1016/j.bmc.2013.07.045 10.7270/Q20P11GK 23981939 Banister, SD; Manoli, M; Barron, ML; Werry, EL; Kassiou, M The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71450549 163350390 CHEMBL2205831 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51078605 CN(CCc1ccccc1)[C@@H]1C2C3CC4C5CC(C2C35)C14 InChI=1S/C20H25N/c1-21(8-7-11-5-3-2-4-6-11)20-17-13-10-14-16-12(13)9-15(17)18(16)19(14)20/h2-6,12-20H,7-10H2,1H3/t12?,13?,14?,15?,16?,17?,18?,19?,20-/m0/s1 MJOVYQVAQIHDSE-DKSPCFMDSA-N 50440995 CHEMBL2432058 D(2) dopamine receptor Homo sapiens 5096 ChEMBL 10.1016/j.bmc.2013.07.045 10.7270/Q20P11GK 23981939 Banister, SD; Manoli, M; Barron, ML; Werry, EL; Kassiou, M The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50440995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50440995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73349361 175453312 CHEMBL2432058 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499444 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccco1 InChI=1S/C24H30N4O2S/c29-24(21-5-3-17-30-21)25-19-9-7-18(8-10-19)11-12-27-13-15-28(16-14-27)23-20-4-1-2-6-22(20)31-26-23/h1-6,17-19H,7-16H2,(H,25,29)/t18-,19- AAELEHAFAYIZRH-WGSAOQKQSA-N 50207145 CHEMBL3946995::US9550741, I-1 D(2) dopamine receptor Homo sapiens 2.90 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207145&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342156 375981455 CHEMBL3946995 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499445 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1 InChI=1S/C24H30N4OS2/c29-24(22-6-3-17-30-22)25-19-9-7-18(8-10-19)11-12-27-13-15-28(16-14-27)23-20-4-1-2-5-21(20)31-26-23/h1-6,17-19H,7-16H2,(H,25,29)/t18-,19- AHJHJVULSVKBEA-WGSAOQKQSA-N 50207094 CHEMBL3976282::US9550741, I-2 D(2) dopamine receptor Homo sapiens 0.190 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207094&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342192 375981439 CHEMBL3976282 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 753867 CCN1CCCC1CNC(=O)c1cc(c(NC)cc1OC)S(=O)(=O)CC InChI=1S/C18H29N3O4S/c1-5-21-9-7-8-13(21)12-20-18(22)14-10-17(26(23,24)6-2)15(19-3)11-16(14)25-4/h10-11,13,19H,5-9,12H2,1-4H3,(H,20,22) NXKXZXNNWRYXRE-UHFFFAOYSA-N 313180 4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl))-2-methoxybenzamide ::US10167256, Compound 102::US10259786, Compound 102 D(2) dopamine receptor Homo sapiens 8.90 US Patent 10.7270/Q2377C1M aid1798362 US10259786 Vaino, AR; Grattan, VT; Prensky, Z LB PHARMACEUTICALS INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313180&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134542980 383540100 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 753868 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 3.60 US Patent 10.7270/Q2377C1M aid1798362 US10259786 Vaino, AR; Grattan, VT; Prensky, Z LB PHARMACEUTICALS INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 753869 CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) NTJOBXMMWNYJFB-UHFFFAOYSA-N 81790 Amisulpride::CAS_71675-85-9::NSC_2159::US10167256, Amisulpride::US10259786, Amisulpride D(2) dopamine receptor Homo sapiens 1.50 US Patent 10.7270/Q2377C1M aid1798362 US10259786 Vaino, AR; Grattan, VT; Prensky, Z LB PHARMACEUTICALS INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2159 131342364 64045 DB06288 963 ZINC01846088 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 753870 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 7100 US Patent 10.7270/Q2377C1M aid1798362 US10259786 Vaino, AR; Grattan, VT; Prensky, Z LB PHARMACEUTICALS INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 753871 CCN1CCCC1CNC(=O)c1cc(c(NC)cc1OC)S(=O)(=O)CC InChI=1S/C18H29N3O4S/c1-5-21-9-7-8-13(21)12-20-18(22)14-10-17(26(23,24)6-2)15(19-3)11-16(14)25-4/h10-11,13,19H,5-9,12H2,1-4H3,(H,20,22) NXKXZXNNWRYXRE-UHFFFAOYSA-N 313180 4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl))-2-methoxybenzamide ::US10167256, Compound 102::US10259786, Compound 102 D(2) dopamine receptor Homo sapiens 8.20 US Patent 10.7270/Q2377C1M aid1798363 US10259786 Vaino, AR; Grattan, VT; Prensky, Z LB PHARMACEUTICALS INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313180&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134542980 383540100 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 753872 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 10.4 US Patent 10.7270/Q2377C1M aid1798363 US10259786 Vaino, AR; Grattan, VT; Prensky, Z LB PHARMACEUTICALS INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 753873 CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) NTJOBXMMWNYJFB-UHFFFAOYSA-N 81790 Amisulpride::CAS_71675-85-9::NSC_2159::US10167256, Amisulpride::US10259786, Amisulpride D(2) dopamine receptor Homo sapiens 8.50 US Patent 10.7270/Q2377C1M aid1798363 US10259786 Vaino, AR; Grattan, VT; Prensky, Z LB PHARMACEUTICALS INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2159 131342364 64045 DB06288 963 ZINC01846088 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 753874 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 2800 US Patent 10.7270/Q2377C1M aid1798363 US10259786 Vaino, AR; Grattan, VT; Prensky, Z LB PHARMACEUTICALS INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38711 CSc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C27H37N3OS/c1-32-26-15-7-6-14-25(26)30-20-18-29(19-21-30)17-8-2-3-16-27(31)28-24-13-9-11-22-10-4-5-12-23(22)24/h4-7,10,12,14-15,24H,2-3,8-9,11,13,16-21H2,1H3,(H,28,31) JNBBJUHCODFLEG-UHFFFAOYSA-N 21367 6-{4-[2-(methylsulfanyl)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL225284::LP-44::Piperazinehexanamide derivative, 5 D(2) dopamine receptor Homo sapiens 7.3 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21367&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11224758 49689439 CHEMBL225284 ZINC13586566 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38712 COc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C27H37N3O2/c1-32-26-15-7-6-14-25(26)30-20-18-29(19-21-30)17-8-2-3-16-27(31)28-24-13-9-11-22-10-4-5-12-23(22)24/h4-7,10,12,14-15,24H,2-3,8-9,11,13,16-21H2,1H3,(H,28,31) HNLISXDOJMLKAY-UHFFFAOYSA-N 21368 6-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL224820::Piperazinehexanamide derivative, 6 D(2) dopamine receptor Homo sapiens 26.4 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11432177 49689440 CHEMBL224820 ZINC13586534 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38713 Cc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C27H37N3O/c1-22-10-4-7-15-26(22)30-20-18-29(19-21-30)17-8-2-3-16-27(31)28-25-14-9-12-23-11-5-6-13-24(23)25/h4-7,10-11,13,15,25H,2-3,8-9,12,14,16-21H2,1H3,(H,28,31) JINXBCRENWAIPY-UHFFFAOYSA-N 21369 6-[4-(2-methylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL222755::Piperazinehexanamide derivative, 7 D(2) dopamine receptor Homo sapiens 143 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11785183 49689441 CHEMBL222755 ZINC13586576 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38714 CC(=O)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C28H37N3O2/c1-22(32)24-12-6-7-15-27(24)31-20-18-30(19-21-31)17-8-2-3-16-28(33)29-26-14-9-11-23-10-4-5-13-25(23)26/h4-7,10,12-13,15,26H,2-3,8-9,11,14,16-21H2,1H3,(H,29,33) NTIASQFANBLTMM-UHFFFAOYSA-N 21370 6-[4-(2-acetylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL389718::Piperazinehexanamide derivative, 8 D(2) dopamine receptor Homo sapiens 68 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21370&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11282296 49689442 CHEMBL389718 ZINC13586546 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38715 Oc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C26H35N3O2/c30-25-14-6-5-13-24(25)29-19-17-28(18-20-29)16-7-1-2-15-26(31)27-23-12-8-10-21-9-3-4-11-22(21)23/h3-6,9,11,13-14,23,30H,1-2,7-8,10,12,15-20H2,(H,27,31) JYEKEEYIUIJIPG-UHFFFAOYSA-N 21371 6-[4-(2-hydroxyphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL225512::Piperazinehexanamide derivative, 9 D(2) dopamine receptor Homo sapiens 987 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21371&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11191128 49689443 CHEMBL225512 ZINC13586570 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38716 O=C(CCCCCN1CCN(CC1)c1ccccc1)NC1CCCc2ccccc12 InChI=1S/C26H35N3O/c30-26(27-25-15-9-11-22-10-6-7-14-24(22)25)16-5-2-8-17-28-18-20-29(21-19-28)23-12-3-1-4-13-23/h1,3-4,6-7,10,12-14,25H,2,5,8-9,11,15-21H2,(H,27,30) OPNMLXKOFJADTH-UHFFFAOYSA-N 21372 6-(4-phenylpiperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL222188::Piperazinehexanamide derivative, 10 D(2) dopamine receptor Homo sapiens 1000 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21372&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11431530 49689444 CHEMBL222188 ZINC13586578 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38717 [O-][N+](=O)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C26H34N4O3/c31-26(27-23-12-8-10-21-9-3-4-11-22(21)23)15-2-1-7-16-28-17-19-29(20-18-28)24-13-5-6-14-25(24)30(32)33/h3-6,9,11,13-14,23H,1-2,7-8,10,12,15-20H2,(H,27,31) ZBUOQRCOVPVZEE-UHFFFAOYSA-N 21373 6-[4-(2-nitrophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL225571::Piperazinehexanamide derivative, 11 D(2) dopamine receptor Homo sapiens 681 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21373&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11329254 49689445 CHEMBL225571 ZINC13586574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38718 Clc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C26H34ClN3O/c27-23-12-5-6-14-25(23)30-19-17-29(18-20-30)16-7-1-2-15-26(31)28-24-13-8-10-21-9-3-4-11-22(21)24/h3-6,9,11-12,14,24H,1-2,7-8,10,13,15-20H2,(H,28,31) OVYNZBZCWFALNG-UHFFFAOYSA-N 21374 6-[4-(2-chlorophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL222477::Piperazinehexanamide derivative, 12 D(2) dopamine receptor Homo sapiens 51 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11385992 49689446 CHEMBL222477 ZINC13586572 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38719 O=C(CCCCCN1CCN(CC1)c1ccccc1C#N)NC1CCCc2ccccc12 InChI=1S/C27H34N4O/c28-21-23-10-4-6-14-26(23)31-19-17-30(18-20-31)16-7-1-2-15-27(32)29-25-13-8-11-22-9-3-5-12-24(22)25/h3-6,9-10,12,14,25H,1-2,7-8,11,13,15-20H2,(H,29,32) GKCVNAHJIZRKPK-UHFFFAOYSA-N 21375 6-[4-(2-cyanophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL221513::Piperazinehexanamide derivative, 13 D(2) dopamine receptor Homo sapiens 265 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11248332 49689447 CHEMBL221513 ZINC13586544 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38720 NC(=O)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C27H36N4O2/c28-27(33)23-12-5-6-14-25(23)31-19-17-30(18-20-31)16-7-1-2-15-26(32)29-24-13-8-10-21-9-3-4-11-22(21)24/h3-6,9,11-12,14,24H,1-2,7-8,10,13,15-20H2,(H2,28,33)(H,29,32) CUNIRIUQESLLLU-UHFFFAOYSA-N 21376 2-{4-[5-(1,2,3,4-tetrahydronaphthalen-1-ylcarbamoyl)pentyl]piperazin-1-yl}benzamide::CHEMBL222489::Piperazinehexanamide derivative, 14 D(2) dopamine receptor Homo sapiens >1000 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11341394 49689448 CHEMBL222489 ZINC13586564 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38721 CS(=O)(=O)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C27H37N3O3S/c1-34(32,33)26-15-7-6-14-25(26)30-20-18-29(19-21-30)17-8-2-3-16-27(31)28-24-13-9-11-22-10-4-5-12-23(22)24/h4-7,10,12,14-15,24H,2-3,8-9,11,13,16-21H2,1H3,(H,28,31) NXWSVHVNLWEBAY-UHFFFAOYSA-N 21377 6-[4-(2-methanesulfonylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL387738::Piperazinehexanamide derivative, 15 D(2) dopamine receptor Homo sapiens >1000 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11283795 49689449 CHEMBL387738 ZINC13586568 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38722 CCc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C28H39N3O/c1-2-23-11-6-8-16-27(23)31-21-19-30(20-22-31)18-9-3-4-17-28(32)29-26-15-10-13-24-12-5-7-14-25(24)26/h5-8,11-12,14,16,26H,2-4,9-10,13,15,17-22H2,1H3,(H,29,32) VCNZQKOEJRCPML-UHFFFAOYSA-N 21378 6-[4-(2-ethylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 16 D(2) dopamine receptor Homo sapiens 173 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768516 49689450 ZINC14975956 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38723 CCCc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C29H41N3O/c1-2-11-25-13-6-8-17-28(25)32-22-20-31(21-23-32)19-9-3-4-18-29(33)30-27-16-10-14-24-12-5-7-15-26(24)27/h5-8,12-13,15,17,27H,2-4,9-11,14,16,18-23H2,1H3,(H,30,33) IIEKSILFYZPUHU-UHFFFAOYSA-N 21379 6-[4-(2-propylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 17 D(2) dopamine receptor Homo sapiens 123 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768517 49689451 ZINC14975964 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38724 CCCCc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C30H43N3O/c1-2-3-12-26-14-7-9-18-29(26)33-23-21-32(22-24-33)20-10-4-5-19-30(34)31-28-17-11-15-25-13-6-8-16-27(25)28/h6-9,13-14,16,18,28H,2-5,10-12,15,17,19-24H2,1H3,(H,31,34) GLAJHBSVLZCXST-UHFFFAOYSA-N 21380 6-[4-(2-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 18 D(2) dopamine receptor Homo sapiens 60.0 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768518 49689452 ZINC14975970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38725 CC(C)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C29H41N3O/c1-23(2)25-13-7-8-16-28(25)32-21-19-31(20-22-32)18-9-3-4-17-29(33)30-27-15-10-12-24-11-5-6-14-26(24)27/h5-8,11,13-14,16,23,27H,3-4,9-10,12,15,17-22H2,1-2H3,(H,30,33) CPWLTNLRAGBWKJ-UHFFFAOYSA-N 21381 6-{4-[2-(propan-2-yl)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 19 D(2) dopamine receptor Homo sapiens 15.0 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23643663 49689453 ZINC14975978 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38726 CC(C)(C)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C30H43N3O/c1-30(2,3)26-15-8-9-17-28(26)33-22-20-32(21-23-33)19-10-4-5-18-29(34)31-27-16-11-13-24-12-6-7-14-25(24)27/h6-9,12,14-15,17,27H,4-5,10-11,13,16,18-23H2,1-3H3,(H,31,34) BLCHSWWAUDRFLL-UHFFFAOYSA-N 21382 6-[4-(2-tert-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 20 D(2) dopamine receptor Homo sapiens >1000 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768519 49689454 ZINC14975984 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38727 O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)NC1CCCc2ccccc12 InChI=1S/C32H39N3O/c36-32(33-30-18-11-15-26-14-6-7-16-28(26)30)20-5-2-10-21-34-22-24-35(25-23-34)31-19-9-8-17-29(31)27-12-3-1-4-13-27/h1,3-4,6-9,12-14,16-17,19,30H,2,5,10-11,15,18,20-25H2,(H,33,36) NMZIDFFHGCRAJV-UHFFFAOYSA-N 21383 6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::NCGC00186032::Piperazinehexanamide derivative, 21 D(2) dopamine receptor Homo sapiens 224 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23643664 49689455 ZINC14975990 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38728 CN(C)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C28H40N4O/c1-30(2)26-15-7-8-16-27(26)32-21-19-31(20-22-32)18-9-3-4-17-28(33)29-25-14-10-12-23-11-5-6-13-24(23)25/h5-8,11,13,15-16,25H,3-4,9-10,12,14,17-22H2,1-2H3,(H,29,33) AYPZPRUFAPTKJJ-UHFFFAOYSA-N 21384 6-{4-[2-(dimethylamino)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 22 D(2) dopamine receptor Homo sapiens 32 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21384&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23643870 49689456 ZINC14975996 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38729 CNc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C27H38N4O/c1-28-25-13-6-7-15-26(25)31-20-18-30(19-21-31)17-8-2-3-16-27(32)29-24-14-9-11-22-10-4-5-12-23(22)24/h4-7,10,12-13,15,24,28H,2-3,8-9,11,14,16-21H2,1H3,(H,29,32) MOARTSKNGANIHC-UHFFFAOYSA-N 21385 6-{4-[2-(methylamino)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 23 D(2) dopamine receptor Homo sapiens 107 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21385&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768520 49689457 ZINC14976004 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38730 CC(=O)Nc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C28H38N4O2/c1-22(33)29-26-13-6-7-15-27(26)32-20-18-31(19-21-32)17-8-2-3-16-28(34)30-25-14-9-11-23-10-4-5-12-24(23)25/h4-7,10,12-13,15,25H,2-3,8-9,11,14,16-21H2,1H3,(H,29,33)(H,30,34) DFLMNRNLACOXKM-UHFFFAOYSA-N 21387 6-[4-(2-acetamidophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 25 D(2) dopamine receptor Homo sapiens >1000 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21387&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768522 49689459 ZINC14976017 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38731 CS(=O)(=O)Nc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C27H38N4O3S/c1-35(33,34)29-25-13-6-7-15-26(25)31-20-18-30(19-21-31)17-8-2-3-16-27(32)28-24-14-9-11-22-10-4-5-12-23(22)24/h4-7,10,12-13,15,24,29H,2-3,8-9,11,14,16-21H2,1H3,(H,28,32) PUVLRPJSGDJKOF-UHFFFAOYSA-N 21388 6-[4-(2-methanesulfonamidophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 26 D(2) dopamine receptor Homo sapiens >1000 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21388&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768523 49689460 ZINC14976024 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38732 Fc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 InChI=1S/C26H34FN3O/c27-23-12-5-6-14-25(23)30-19-17-29(18-20-30)16-7-1-2-15-26(31)28-24-13-8-10-21-9-3-4-11-22(21)24/h3-6,9,11-12,14,24H,1-2,7-8,10,13,15-20H2,(H,28,31) GJXLROXNFUKMEK-UHFFFAOYSA-N 21389 6-[4-(2-fluorophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 27 D(2) dopamine receptor Homo sapiens 292 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21389&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768524 49689461 ZINC14976030 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38733 O=C(CCCCCN1CCN(CC1)c1ccccn1)NC1CCCc2ccccc12 InChI=1S/C25H34N4O/c30-25(27-23-12-8-10-21-9-3-4-11-22(21)23)14-2-1-7-16-28-17-19-29(20-18-28)24-13-5-6-15-26-24/h3-6,9,11,13,15,23H,1-2,7-8,10,12,14,16-20H2,(H,27,30) XJYAXSYLDGSUII-UHFFFAOYSA-N 21390 6-[4-(pyridin-2-yl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 28 D(2) dopamine receptor Homo sapiens >1000 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21390&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768525 49689462 ZINC14976037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38734 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.0 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 38735 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.093 Curated from the literature by BindingDB 10.1021/jm070487n 10.7270/Q20000CJ 17649988 aid1798075 Leopoldo, M; Lacivita, E; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51926 NCCC(=O)Nc1ccc2cnn(c2c1)S(=O)(=O)c1cccc2ccccc12 InChI=1S/C20H18N4O3S/c21-11-10-20(25)23-16-9-8-15-13-22-24(18(15)12-16)28(26,27)19-7-3-5-14-4-1-2-6-17(14)19/h1-9,12-13H,10-11,21H2,(H,23,25) YSQAQADMLFUOTE-UHFFFAOYSA-N 28574 1-sulfonylindazole, 6c::3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]propanamide D(2) dopamine receptor Homo sapiens >2000 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.03.071 10.7270/Q28K77CF 19345582 aid1798907 Liu, KG; Lo, JR; Comery, TA; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Di, L; Kerns, EH; Schechter, LE; Robichaud, AJ Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23624307 58097762 ZINC40410741 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 51927 O=C(Nc1ccc2cnn(c2c1)S(=O)(=O)c1cccc2ccccc12)C1CCNCC1 InChI=1S/C23H22N4O3S/c28-23(17-10-12-24-13-11-17)26-19-9-8-18-15-25-27(21(18)14-19)31(29,30)22-7-3-5-16-4-1-2-6-20(16)22/h1-9,14-15,17,24H,10-13H2,(H,26,28) KVDHEMNUTADYJJ-UHFFFAOYSA-N 28579 1-sulfonylindazole, 7a::N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]piperidine-4-carboxamide D(2) dopamine receptor Homo sapiens >2000 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.03.071 10.7270/Q28K77CF 19345582 aid1798907 Liu, KG; Lo, JR; Comery, TA; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Di, L; Kerns, EH; Schechter, LE; Robichaud, AJ Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24771120 58097767 ZINC40943355 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 157156 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.94 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 157159 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.4 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 157162 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Homo sapiens 2685 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 157165 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Homo sapiens 2145 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 157168 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.125 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 157171 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 206 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 157185 Clc1cccc(c1)N1CCNCC1 InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 VHFVKMTVMIZMIK-UHFFFAOYSA-N 50001915 1-(3-chlorophenyl)piperazine::CHEMBL478::m-Chlorophenylpiperazine::mCPP D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/0006-3223(89)90217-5 10.7270/Q2MP51R8 2537663 Hamik, A; Peroutka, SJ Stanford University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001915&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1355 103916282 10588 CHEMBL478 142 C11738 ZINC00004285 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155995 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 1.2 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155996 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.68 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155997 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.83 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155998 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 1.8 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155999 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 330 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156000 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 176 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156001 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 130 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156002 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 143 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156003 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 149 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156004 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Homo sapiens 0.6 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156005 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Homo sapiens 2.3 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156006 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Homo sapiens 0.66 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156007 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Homo sapiens 0.73 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156008 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Homo sapiens 2.5 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156009 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.05 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156010 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.07 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156011 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.06 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156012 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.07 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156013 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.08 PDSP Ki 10.7270/Q2J38R16 1828505 Joyce, JN; Janowsky, A; Neve, KA University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156049 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 12.6 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156051 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.8 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156052 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 1.5 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156054 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 138 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156064 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156077 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Homo sapiens 3.2 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156078 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Homo sapiens 10.5 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156081 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Homo sapiens 913 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156084 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.053 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156085 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.05 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156086 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.03 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156088 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Homo sapiens 46 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156089 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Homo sapiens 31 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156096 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Homo sapiens 0.09 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155412 CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) NTJOBXMMWNYJFB-UHFFFAOYSA-N 81790 Amisulpride::CAS_71675-85-9::NSC_2159::US10167256, Amisulpride::US10259786, Amisulpride D(2) dopamine receptor Homo sapiens 1.3 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2159 131342364 64045 DB06288 963 ZINC01846088 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155413 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 63 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155414 NC(=O)C1(CCN(CCCN2c3ccccc3CCc3ccccc23)CC1)N1CCCCC1 InChI=1S/C28H38N4O/c29-27(33)28(31-18-6-1-7-19-31)15-21-30(22-16-28)17-8-20-32-25-11-4-2-9-23(25)13-14-24-10-3-5-12-26(24)32/h2-5,9-12H,1,6-8,13-22H2,(H2,29,33) NWPJLRSCSQHPJV-UHFFFAOYSA-N 81794 CAS_5942-95-0::Carpipramine::NSC_2580 D(2) dopamine receptor Homo sapiens 8.7 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81794&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2580 131342368 C12896 ZINC22005792 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155415 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 2.3 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155416 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 69 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155417 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Homo sapiens 1.3 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155418 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 544 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155419 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)NP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H17N6O13P3/c11-10-13-7-4(8(19)14-10)12-2-16(7)9-6(18)5(17)3(28-9)1-27-32(25,26)29-31(23,24)15-30(20,21)22/h2-3,5-6,9,17-18H,1H2,(H,25,26)(H3,11,13,14,19)(H4,15,20,21,22,23,24)/t3-,5-,6-,9-/m1/s1 UQABYHGXWYXDTK-UUOKFMHZSA-N 81791 Dopamine + GPP(NH)p::GPP(NH)P(+)::GPP(NH)p(-)::Guanylyl imidodiphosphate D(2) dopamine receptor Homo sapiens 2059 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 36735 131342365 C02058 ZINC37868676 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155420 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.6 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155421 CCS(=O)(=O)c1cc(C(=O)NCC2CCCN2CC2CC2)c(OC)cc1I InChI=1S/C19H27IN2O4S/c1-3-27(24,25)18-9-15(17(26-2)10-16(18)20)19(23)21-11-14-5-4-8-22(14)12-13-6-7-13/h9-10,13-14H,3-8,11-12H2,1-2H3,(H,21,23) QICCKJBXMXZXJQ-UHFFFAOYSA-N 81796 CAS_122245::Iodosulpride::NSC_122245 D(2) dopamine receptor Homo sapiens 0.5 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122245 131342370 ZINC14953439 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155422 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50028421 9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid::CHEMBL1275::LY-127809::PERGOLIDE MESYLATE::Pergolide::Permax D(2) dopamine receptor Homo sapiens 19 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103937709 8021 CHEMBL1275 DB01186 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155423 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 9.8 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155424 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCC(CCO)CC3)c2c1 InChI=1S/C24H33N3O3S2/c1-25(2)32(29,30)20-8-9-24-22(18-20)27(21-6-3-4-7-23(21)31-24)14-5-13-26-15-10-19(11-16-26)12-17-28/h3-4,6-9,18-19,28H,5,10-17H2,1-2H3 JOMHSQGEWSNUKU-UHFFFAOYSA-N 81798 CAS_39860-99-6::NSC_62867::Pipotiazine D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 62867 131342372 DB01621 ZINC03813024 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155425 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 78434 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499 D(2) dopamine receptor Homo sapiens 0.4 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P77 3M0W 4917 252655190 8435 DB00433 C07403 ZINC19796018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155426 CCCN1CCC[C@@H]2Cc3nc(N)ncc3C[C@@H]12 InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m1/s1 TUFADSGTJUOBEH-ZWNOBZJWSA-N 50016017 (5aR,9aR)-6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine::(5aR,9aR)-6-propyl-5,5a,6,7,8,9,9a,10-octahydropyrido[2,3-g]quinazolin-2-amine::6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine(Quinelorane)::CHEMBL155731::Quinelorane::Quinerolane D(2) dopamine receptor Homo sapiens 341 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57242 103927698 CHEMBL155731 954 ZINC00005041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155427 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 1402 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155428 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Homo sapiens 198 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155429 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 10 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156688 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 1.5 PDSP Ki 10.7270/Q2Z60MJ0 2137193 Stormann, TM; Gdula, DC; Weiner, DM; Brann, MR National Institute of Neurological Disorders and Stroke http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156689 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2Z60MJ0 2137193 Stormann, TM; Gdula, DC; Weiner, DM; Brann, MR National Institute of Neurological Disorders and Stroke http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156690 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 5450 PDSP Ki 10.7270/Q2Z60MJ0 2137193 Stormann, TM; Gdula, DC; Weiner, DM; Brann, MR National Institute of Neurological Disorders and Stroke http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 156691 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 46 PDSP Ki 10.7270/Q2Z60MJ0 2137193 Stormann, TM; Gdula, DC; Weiner, DM; Brann, MR National Institute of Neurological Disorders and Stroke http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155430 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCN(C)CC3)c2c1 InChI=1S/C22H30N4O2S2/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25/h4-5,7-10,17H,6,11-16H2,1-3H3 VZYCZNZBPPHOFY-UHFFFAOYSA-N 81793 CAS_316-81-4::NSC_92178::Thioproperazine D(2) dopamine receptor Homo sapiens 0.45 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9429 131342367 DB01622 ZINC22446685 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155431 C[NH+](C)C1CCc2cc(O)c(O)cc2C1 InChI=1S/C12H17NO2/c1-13(2)10-4-3-8-6-11(14)12(15)7-9(8)5-10/h6-7,10,14-15H,3-5H2,1-2H3/p+1 JWLJBTDXCBIGBW-UHFFFAOYSA-O 50025206 (6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-ammonium::TL99 D(2) dopamine receptor Homo sapiens 66 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025206&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299913 103935110 ZINC05965207 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 155432 CCCN(CCC)C1C=Cc2c(OC)cccc2C1C InChI=1S/C18H27NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-11,14,17H,5-6,12-13H2,1-4H3 YNNTVNSZMGTKJL-UHFFFAOYSA-N 81792 CAS_5311190::NSC_5311190::UH232::UH232(+) D(2) dopamine receptor Homo sapiens 36 PDSP Ki 10.7270/Q2QR4VK6 1586393 Sokoloff, P; Giros, B; Martres, MP; Andrieux, M; Besancon, R; Pilon, C; Bouthenet, ML; Souil, E; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54592327 131342366 ZINC14953308 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158045 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 18.86 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158046 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 178.57 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158047 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.86 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158048 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Homo sapiens 0.8 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158049 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 4 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158050 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 71.42 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158051 CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 SLVMESMUVMCQIY-UHFFFAOYSA-N 50131440 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23 D(2) dopamine receptor Homo sapiens 18.86 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4078 104022598 6780 CHEMBL1088 DB00933 7227 C07143 ZINC03831042 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158052 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Homo sapiens 120.48 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158053 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 RGCVKNLCSQQDEP-UHFFFAOYSA-N 50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine D(2) dopamine receptor Homo sapiens 1.4 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4748 104021707 8028 CHEMBL567 DB00850 209 C07427 ZINC19228902 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158054 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 78434 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499 D(2) dopamine receptor Homo sapiens 7.14 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P77 3M0W 4917 252655190 8435 DB00433 C07403 ZINC19796018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158055 CN(C)CCCN1c2ccccc2Sc2ccccc12 InChI=1S/C17H20N2S/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19/h3-6,8-11H,7,12-13H2,1-2H3 ZGUGWUXLJSTTMA-UHFFFAOYSA-N 67545 N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride::PROMAZINE::SR-01000000228-4::US9504692, Promazine::cid_5887::dimethyl(3-phenothiazin-10-ylpropyl)amine;hydrochloride D(2) dopamine receptor Homo sapiens 161.29 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P2Z 7LGI,4MA7 4926 252645840 DB00420 C07379 ZINC00010402 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158056 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.16 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158057 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 26.31 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158058 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- GFBKORZTTCHDGY-UWVJOHFNSA-N 78576 CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene D(2) dopamine receptor Homo sapiens 0.45 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941651 252655323 DB01623 212 ZINC30690433 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158059 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Homo sapiens 2.63 PDSP Ki 10.1111/j.1749-6632.1988.tb42125.x 10.7270/Q2X065JH 2904784 Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 159705 CN1CCC[C@H]1c1cc(C)no1 InChI=1S/C9H14N2O/c1-7-6-9(12-10-7)8-4-3-5-11(8)2/h6,8H,3-5H2,1-2H3/t8-/m0/s1 ILLGYRJAYAAAEW-QMMMGPOBSA-N 50035398 (S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidinium::(S)-3-methyl-5-(1-methylpyrrolidin-2-yl)isoxazole::3-Methyl-5-((S)-1-methyl-pyrrolidin-2-yl)-isoxazole::ABT-418::CHEMBL274525 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2HH6HKJ 7518514 Arneric, SP; Sullivan, JP; Briggs, CA; Donnelly-Roberts, D; Anderson, DJ; Raszkiewicz, JL; Hughes, ML; Cadman, ED; Adams, P; Garvey, DS Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119380 103943417 CHEMBL274525 ZINC03786099 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163513 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Homo sapiens 60 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163514 NC1CCc2cc(OC(=O)c3ccccc3)c(OC(=O)c3ccccc3)cc2C1 InChI=1S/C24H21NO4/c25-20-12-11-18-14-21(28-23(26)16-7-3-1-4-8-16)22(15-19(18)13-20)29-24(27)17-9-5-2-6-10-17/h1-10,14-15,20H,11-13,25H2 GSKLFVJWZBQVTK-UHFFFAOYSA-N 82565 ADTN 5,6::CAS_129816::NSC_129816 D(2) dopamine receptor Homo sapiens 530 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129816 136350535 ZINC06095845 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163515 NC1CCc2ccc(OC(=O)c3ccccc3)c(OC(=O)c3ccccc3)c2C1 InChI=1S/C24H21NO4/c25-19-13-11-16-12-14-21(28-23(26)17-7-3-1-4-8-17)22(20(16)15-19)29-24(27)18-9-5-2-6-10-18/h1-10,12,14,19H,11,13,15,25H2 XWNUNQVSZJKLLO-UHFFFAOYSA-N 82566 ADTN 6,7 D(2) dopamine receptor Homo sapiens 55 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339690 136350536 ZINC87722109 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163516 Cc1cc2CCC(N)Cc2cc1C InChI=1S/C12H17N/c1-8-5-10-3-4-12(13)7-11(10)6-9(8)2/h5-6,12H,3-4,7,13H2,1-2H3 UJCKJEXZFPZLSZ-UHFFFAOYSA-N 82568 ADTN DIMETHYL 5,6 D(2) dopamine receptor Homo sapiens 30 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23844117 136350538 ZINC87722115 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163517 Cc1ccc2CCC(N)Cc2c1C InChI=1S/C12H17N/c1-8-3-4-10-5-6-11(13)7-12(10)9(8)2/h3-4,11H,5-7,13H2,1-2H3 PAXCCNFUSNZUFW-UHFFFAOYSA-N 82567 ADTN DIMETHYL 6,7 D(2) dopamine receptor Homo sapiens 20 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339691 136350537 ZINC89455227 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163518 CCCN(CCC)C1CCc2cc(O)c(O)cc2C1 InChI=1S/C16H25NO2/c1-3-7-17(8-4-2)14-6-5-12-10-15(18)16(19)11-13(12)9-14/h10-11,14,18-19H,3-9H2,1-2H3 YNJJGTRJAAGQAD-UHFFFAOYSA-N 85091 (+/-)-2-DIPROPYLAMINO- 6,7-DIHYDROXY-1,2,3,4-TETRAHYDRONAPHTHALENE::ADTN DIPROPYL 6,7::CAS_62421-17-4::CHEMBL15887::dp-ADTN D(2) dopamine receptor Homo sapiens 25 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85091&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 125246 136351191 CHEMBL15887 ZINC05833106 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163519 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 30 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163520 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 0.62 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163521 COc1ccc2C[C@@H]3N(C)CCc4cc5OCOc5c(c34)-c2c1O InChI=1S/C19H19NO4/c1-20-6-5-11-8-14-19(24-9-23-14)17-15(11)12(20)7-10-3-4-13(22-2)18(21)16(10)17/h3-4,8,12,21H,5-7,9H2,1-2H3/t12-/m0/s1 LODGIKWNLDQZBM-LBPRGKRZSA-N 50016018 (S)-11-methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-12-ol::11-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-12-ol (Bulbocapnine)::Bulbocapnine::CHEMBL157912 D(2) dopamine receptor Homo sapiens 1500 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12441 103927699 CHEMBL157912 C09367 ZINC00000103 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163522 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163523 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.44 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163524 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 8 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163525 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 38 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163526 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Homo sapiens 0.58 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163527 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 710 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163528 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Homo sapiens 1.5 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163529 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Homo sapiens 120 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163530 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.6 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163531 CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C21H27NO/c1-2-14-22(15-13-17-7-4-3-5-8-17)19-11-12-20-18(16-19)9-6-10-21(20)23/h3-10,19,23H,2,11-16H2,1H3 DEYFWGXTPWNADC-UHFFFAOYSA-N 50010289 (R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(RS)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL109684::N-0434 D(2) dopamine receptor Homo sapiens 5.9 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1240 103923108 CHEMBL109684 ZINC02169418 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163532 CCCN1CCO[C@H]2[C@H]1CCc1ccc(O)cc21 InChI=1S/C15H21NO2/c1-2-7-16-8-9-18-15-13-10-12(17)5-3-11(13)4-6-14(15)16/h3,5,10,14-15,17H,2,4,6-9H2,1H3/t14-,15-/m1/s1 JCSREICEMHWFAY-HUUCEWRRSA-N 50020217 (4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol::CHEMBL69271::NAXAGOLIDE HYDROCHLORIDE::PHNO::PHNO,(+) D(2) dopamine receptor Homo sapiens 8.5 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020217&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57533 103931131 CHEMBL69271 ZINC22064446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163533 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 0.39 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163534 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 600 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163535 CCCN1CCc2cc(F)cc-3c2C1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20FNO2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9H2,1H3 TVIUJNLDORXPPC-UHFFFAOYSA-N 82569 CAS_18426-20-5::NSC_131212::R(-)NPA D(2) dopamine receptor Homo sapiens 0.12 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14728695 136350539 ZINC26841490 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163536 CC1CN(CCCn2c3ccccc3c3ccccc23)CC(C)N1 InChI=1S/C21H27N3/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3 GUDVQJXODNJRIJ-UHFFFAOYSA-N 50002294 9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole(rimcazole)::9-[3-(3,5-dimethylpiperazin-1-yl)propyl]-9H-carbazole::RIMCAZOLE D(2) dopamine receptor Homo sapiens 8700 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002294&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5072 103916600 ZINC22920326 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163537 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Homo sapiens 520 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163538 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 520 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163539 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 6 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 159787 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 189 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 159788 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.1 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 159789 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 3.1 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 159790 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 159 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 159791 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.4 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 159792 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 4.7 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163540 CCCN(CCC)C1C=Cc2c(OC)cccc2C1C InChI=1S/C18H27NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-11,14,17H,5-6,12-13H2,1-4H3 YNNTVNSZMGTKJL-UHFFFAOYSA-N 81792 CAS_5311190::NSC_5311190::UH232::UH232(+) D(2) dopamine receptor Homo sapiens 9 PDSP Ki 10.7270/Q2C827SR 8301582 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Neuroscience Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54592327 131342366 ZINC14953308 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161282 CN(C)Cc1nnc2CN=C(c3ccccc3)c3cc(Cl)ccc3-n12 InChI=1S/C19H18ClN5/c1-24(2)12-18-23-22-17-11-21-19(13-6-4-3-5-7-13)15-10-14(20)8-9-16(15)25(17)18/h3-10H,11-12H2,1-2H3 GJSLOMWRLALDCT-UHFFFAOYSA-N 82439 Adinazolam::CAS_37115-32-5::NSC_37632 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37632 136350410 251412 DB00546 ZINC04214740 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161283 CN(C)CCC=C1c2ccccc2CCc2ccccc12 InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3 KRMDCWKBEZIMAB-UHFFFAOYSA-N 50020712 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene::10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine::3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine::3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine::3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine::5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene::5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene::5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene::AMITRIPTYLINE::Amitriptylin::CHEMBL629 D(2) dopamine receptor Homo sapiens 1460 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TP0 8Y93,5HA9,3APV 2160 103931468 2666 CHEMBL629 DB00321 200 C06824 ZINC00968257 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 161284 CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3 SNPPWIUOZRMYNY-UHFFFAOYSA-N 50048392 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one::BUPROPION::BUPROPION HYDROCHLORIDE::CHEMBL894::US9944618, Compound ID No. 176 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048392&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 444 103978858 3219 CHEMBL894 DB01156 7135 C06860 ZINC00057206 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161285 CNCCCN1c2ccccc2CCc2ccccc12 InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3 HCYAFALTSJYZDH-UHFFFAOYSA-N 35229 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine::5-(gamma-methylaminopropyl)iminodibenzyl::CHEMBL72::DESIPRAMINE HYDROCHLORIDE::DMI::Desipramin::Desipramine::Desmethylimipramine::N-(3-methylaminopropyl)iminobibenzyl::US9944618, Compound ID No. 174::demethylimipramine::monodemethylimipramine::norimipramine D(2) dopamine receptor Homo sapiens 3500 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35229&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search DSM 7Q19,2QJU,7Q2N,7Q2O,7Q2P,2QB4 2995 85753308 47781 CHEMBL72 DB01151 2399 C06943 ZINC01530611 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161286 N[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc12 InChI=1S/C16H15Cl2N/c17-14-7-5-10(9-15(14)18)11-6-8-16(19)13-4-2-1-3-12(11)13/h1-5,7,9,11,16H,6,8,19H2/t11-,16-/m0/s1 SRPXSILJHWNFMK-ZBEGNZNMSA-N 50028066 4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-ylamine, HCl::CHEMBL40733::Desmethylsertraline D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028066&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 114743 103937445 CHEMBL40733 ZINC06117444 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161287 CN(C)CC\C=C1\c2ccccc2COc2ccccc12 InChI=1S/C19H21NO/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3/b17-11- ODQWQRRAPPTVAG-BOPFTXTBSA-N 50079527 (3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine(3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine::CHEMBL101740::DOXEPIN::cis-doxepin D(2) dopamine receptor Homo sapiens 360 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search D7V 3RZE 667468 103971748 4710 CHEMBL101740 C06971 ZINC00001148 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161288 CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CC InChI=1S/C19H28ClN5O/c1-3-18-21-25(19(26)24(18)4-2)10-6-9-22-11-13-23(14-12-22)17-8-5-7-16(20)15-17/h5,7-8,15H,3-4,6,9-14H2,1-2H3 IZBNNCFOBMGTQX-UHFFFAOYSA-N 82438 CAS_52942-31-1::Etoperidone::NSC_40589 D(2) dopamine receptor Homo sapiens 2300 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 40589 136350409 DB09194 ZINC03830815 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161289 COc1ccc(OC[C@H]2CN(C)CC[C@@H]2c2ccccc2)cc1 InChI=1S/C20H25NO2/c1-21-13-12-20(16-6-4-3-5-7-16)17(14-21)15-23-19-10-8-18(22-2)9-11-19/h3-11,17,20H,12-15H2,1-2H3/t17-,20-/m1/s1 OJSFTALXCYKKFQ-YLJYHZDGSA-N 50014247 (3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phenyl-piperidine::3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phenyl-piperidine(femoxetine)::CHEMBL94739::Femoxetine D(2) dopamine receptor Homo sapiens 590 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3012003 103926269 CHEMBL94739 ZINC04216004 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161290 CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 RTHCYVBBDHJXIQ-UHFFFAOYSA-N 30130 CHEMBL1201082::CHEMBL41::Fluoxetin::Fluoxetine::Prozac::US9120771, Fluoxetine::cid_62857 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search RFX 4MM8,3GWV 3386 85147891 5118 CHEMBL1201082CHEMBL41 DB00472 203 ZINC01530638 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161291 CN(C)CCCN1c2ccccc2CCc2ccccc12 InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 BCGWQEUPMDMJNV-UHFFFAOYSA-N 50010859 CHEMBL11::IMIPRAMINE HYDROCHLORIDE::IMIPRAMINE PAMOATE::Imipramin D(2) dopamine receptor Homo sapiens 620 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search IXX 2Q72,7LWD,6G9B 3696 103923605 47499 CHEMBL11 DB00458 357 C07049 ZINC00020245 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161292 CN(CCCN1c2ccccc2CCc2ccccc12)CC(=O)c1ccc(Cl)cc1 InChI=1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3 SAPNXPWPAUFAJU-UHFFFAOYSA-N 82437 CAS_23047-25-8::Lofepramine::NSC_3947::US8629135, SW-06 D(2) dopamine receptor Homo sapiens 2000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3947 136350408 47782 ZINC01542929 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161293 CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CCOc1ccccc1 InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3 VRBKIVRKKCLPHA-UHFFFAOYSA-N 50069447 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one::2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one::CHEMBL623::NEFAZODONE::US9138393, Nefazodone HCl::US9144538, Nefazodone HCl D(2) dopamine receptor Homo sapiens 910 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4449 103963508 7494 CHEMBL623 DB01149 7247 C07256 ZINC00538065 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161294 NCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1 InChI=1S/C16H16F3NO/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12/h1-9,15H,10-11,20H2/t15-/m0/s1 WIQRCHMSJFFONW-HNNXBMFYSA-N 50254790 (S)-Norfluoxetine::CHEMBL465123::NORFLUOXETINE D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 405 4XDK 3058751 104106938 CHEMBL465123 ZINC00004531 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161295 CNCCC=C1c2ccccc2CCc2ccccc12 InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3 PHVGLTMQBUFIQQ-UHFFFAOYSA-N 112777 NORTRIPTYLINE::US8629135, SW-02 D(2) dopamine receptor Homo sapiens 2570 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21B 4M48 4543 194690518 DB00540 C07274 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161296 Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 22416 (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::CHEMBL490::PAROXETINE::US09969700, Paroxetine::US9944618, Compound ID No. 182::[3H]Paroxetine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22416&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8PR 6F6I,7OIH,6DZW,6AWN,4JLT,3V5W,4MM4,6VRH,5I6X,4L9I 43815 49846231 7936 CHEMBL490 DB00715 4561 C07415 ZINC00527386 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161297 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 29 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161298 CN[C@@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc12 InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17+/m0/s1 VGKDLMBJGBXTGI-YVEFUNNKSA-N 82217 CHEMBL284994::CP-52003::SERTRALINE::[4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-methyl-amine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82217&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9882979 136350189 CHEMBL284994 ZINC03831445 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161299 CNCCC(Oc1ccccc1C)c1ccccc1 InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3 VHGCDTVCOLNTBX-UHFFFAOYSA-N 50022784 (R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine::ATOMOXETINE::CHEMBL641::Methyl-((R)-3-phenyl-3-o-tolyloxy-propyl)-amine::Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine::Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine(tomoxetine)::Strattera::Tomoxetine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6850813 103933341 CHEMBL641 ZINC02570822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161300 Clc1cccc(c1)N1CCN(CCCn2nc3ccccn3c2=O)CC1 InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2 PHLBKPHSAVXXEF-UHFFFAOYSA-N 50073444 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one::CHEMBL621::TRAZODONE D(2) dopamine receptor Homo sapiens 3500 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5533 103966838 9654 CHEMBL621 DB00656 213 C07156 ZINC00538483 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161301 COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3 PNVNVHUZROJLTJ-UHFFFAOYSA-N 82071 CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1007/BF02244985 10.7270/Q25X27FZ 7855217 Cusack, B; Nelson, A; Richelson, E Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search VFX 8F4W 5656 131342645 DB00285 C07187 ZINC00896698 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 160107 COc1cc(COc2cc(N)c(Cl)cc2C(=O)CCC2CCN(CCNS(C)(=O)=O)CC2)cc(OC)c1 InChI=1S/C26H36ClN3O6S/c1-34-20-12-19(13-21(14-20)35-2)17-36-26-16-24(28)23(27)15-22(26)25(31)5-4-18-6-9-30(10-7-18)11-8-29-37(3,32)33/h12-16,18,29H,4-11,17,28H2,1-3H3 BKVIWGRFRKLFIO-UHFFFAOYSA-N 82273 CAS_167710-87-4::RS 39604 D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1111/j.1476-5381.1995.tb15922.x 10.7270/Q2707ZX4 7582507 Hegde, SS; Bonhaus, DW; Johnson, LG; Leung, E; Clark, RD; Eglen, RM Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5145950 136350245 64081 ZINC03929879 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158885 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.86 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158886 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 19 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158887 CN(C)CC\C=C1/c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7+ WSPOMRSOLSGNFJ-VGOFMYFVSA-N 50130257 (3E)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine::(E)-chlorprothixene::CHEMBL90125::CHLORPROTHIXENE::Chlorprothixene (cis) D(2) dopamine receptor Homo sapiens 8 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 667466 104021691 50932 CHEMBL90125 ZINC31261349 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158888 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 180 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158889 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Homo sapiens 0.8 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158890 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 4 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158891 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 70 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158892 CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 SLVMESMUVMCQIY-UHFFFAOYSA-N 50131440 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23 D(2) dopamine receptor Homo sapiens 19 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4078 104022598 6780 CHEMBL1088 DB00933 7227 C07143 ZINC03831042 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158893 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Homo sapiens 120 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158894 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 RGCVKNLCSQQDEP-UHFFFAOYSA-N 50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine D(2) dopamine receptor Homo sapiens 1.4 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4748 104021707 8028 CHEMBL567 DB00850 209 C07427 ZINC19228902 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158895 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 78434 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499 D(2) dopamine receptor Homo sapiens 7 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P77 3M0W 4917 252655190 8435 DB00433 C07403 ZINC19796018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158896 CN(C)CCCN1c2ccccc2Sc2ccccc12 InChI=1S/C17H20N2S/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19/h3-6,8-11H,7,12-13H2,1-2H3 ZGUGWUXLJSTTMA-UHFFFAOYSA-N 67545 N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride::PROMAZINE::SR-01000000228-4::US9504692, Promazine::cid_5887::dimethyl(3-phenothiazin-10-ylpropyl)amine;hydrochloride D(2) dopamine receptor Homo sapiens 160 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P2Z 7LGI,4MA7 4926 252645840 DB00420 C07379 ZINC00010402 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158897 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.16 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158898 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 26 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158899 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- GFBKORZTTCHDGY-UWVJOHFNSA-N 78576 CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene D(2) dopamine receptor Homo sapiens 0.45 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941651 252655323 DB01623 212 ZINC30690433 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158900 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Homo sapiens 2.6 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 158901 CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3 XSCGXQMFQXDFCW-UHFFFAOYSA-N 67544 N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazinyl]-1-propanamine;hydrochloride::N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine;hydrochloride::SR-01000000224-4::TRIFLUPROMAZINE::cid_66069::dimethyl-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]amine;hydrochloride::med.21724, Compound Triflupromazine D(2) dopamine receptor Homo sapiens 2.8 PDSP Ki 10.1016/0014-2999(84)90478-3 10.7270/Q2WW7G5B 6149136 Richelson, E; Nelson, A Mayo Clinic http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5568 252645839 DB00508 ZINC00538507 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 162981 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Homo sapiens 0.6 PDSP Ki 10.7270/Q2K072SP 8099194 Malmberg, A; Jackson, DM; Eriksson, A; Mohell, N Astra Arcus AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 161891 CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1 InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3 AOOSJYIINXVNHV-UHFFFAOYSA-N 82505 CAS_121881::NSC_121881::SB204070 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1111/j.1476-5381.1994.tb13148.x 10.7270/Q2N0151D 7921604 Wardle, KA; Ellis, ES; Baxter, GS; Kennett, GA; Gaster, LM; Sanger, GJ SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121881 136350476 256 ZINC01536586 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163096 CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1 YGHLYBIUVOLKCV-SMDDNHRTSA-N 50041959 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::AJ76(+)::CHEMBL27441 D(2) dopamine receptor Homo sapiens 120.3 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122334 103973638 64117 CHEMBL27441 970 ZINC03995669 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163097 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 391.6 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163098 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 1.3 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163099 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 81.9 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163100 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.9 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163101 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 9.9 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163102 CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 DKMFBWQBDIGMHM-UHFFFAOYSA-N 81771 CAS_3575-80-2::MELPERONE::NSC_15387 D(2) dopamine receptor Homo sapiens 181.5 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15387 131342345 DB09224 ZINC00001672 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163103 OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22) JXTHEWSKYLZVJC-UHFFFAOYSA-N 81777 CAS_132-66-1::NPA::NPA,(+)::NPA,(-)::NSC_8594 D(2) dopamine receptor Homo sapiens 290.7 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E7O 7QPC,7WKW,7Y9U 8594 131342351 60833 C06374 ZINC00028113 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163104 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Homo sapiens 345.5 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163105 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Homo sapiens 2 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163106 CN1C[C@H](CC2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)NC(=O)C(C)(C)C InChI=1S/C20H26ClN3O/c1-20(2,3)19(25)22-11-8-13-12-6-5-7-15-17(12)14(18(21)23-15)9-16(13)24(4)10-11/h5-7,11,13,16,23H,8-10H2,1-4H3,(H,22,25)/t11-,13?,16+/m0/s1 QXOFQMUQMXGKGQ-VKCPWKDNSA-N 50047138 CHEMBL25074::N-(5-Chloro-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-2,2-dimethyl-propionamide::SDZ-208-912::SDZ-HDC-912 D(2) dopamine receptor Homo sapiens 0.9 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047138&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22849992 103977826 CHEMBL25074 ZINC13826925 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163107 CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1 JOAHPSVPXZTVEP-YXJHDRRASA-N 50017519 1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-urea::CHEMBL73151::Terguride D(2) dopamine receptor Homo sapiens 0.7 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 443951 103928787 CHEMBL73151 ZINC03811327 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163108 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 2.8 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163109 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Homo sapiens 1.1 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 163110 CCCN(CCC)C1C=Cc2c(OC)cccc2C1C InChI=1S/C18H27NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-11,14,17H,5-6,12-13H2,1-4H3 YNNTVNSZMGTKJL-UHFFFAOYSA-N 81792 CAS_5311190::NSC_5311190::UH232::UH232(+) D(2) dopamine receptor Homo sapiens 29.4 PDSP Ki 10.1016/0014-2999(93)90488-4 10.7270/Q25Q4TKG 8102973 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Maryland Psychiatric Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54592327 131342366 ZINC14953308 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 172194 Cn1ccc2cc3N(CCc3cc12)C(=O)Nc1cccnc1 InChI=1S/C17H16N4O/c1-20-7-4-12-10-16-13(9-15(12)20)5-8-21(16)17(22)19-14-3-2-6-18-11-14/h2-4,6-7,9-11H,5,8H2,1H3,(H,19,22) QJQORSLQNXDVGE-UHFFFAOYSA-N 50060417 5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide::CHEMBL297784::SB 206553::SB-206553 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1111/j.1476-5381.1996.tb15208.x 10.7270/Q27W69Q5 8821530 Kennett, GA; Wood, MD; Bright, F; Cilia, J; Piper, DC; Gager, T; Thomas, D; Baxter, GS; Forbes, IT; Ham, P; Blackburn, TP SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060417&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5163 103956180 CHEMBL297784 189 C11740 ZINC00005994 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169851 CN(C)[C@H]1CCc2c1cccc2O InChI=1S/C11H15NO/c1-12(2)10-7-6-9-8(10)4-3-5-11(9)13/h3-5,10,13H,6-7H2,1-2H3/t10-/m0/s1 WVGLNMGYBSTSPE-JTQLQIEISA-N 84633 AI-OH-DP,(+) D(2) dopamine receptor Homo sapiens 5000 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339797 136350733 ZINC36438143 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169852 CN(C)[C@@H]1CCc2c1cccc2O InChI=1S/C11H15NO/c1-12(2)10-7-6-9-8(10)4-3-5-11(9)13/h3-5,10,13H,6-7H2,1-2H3/t10-/m1/s1 WVGLNMGYBSTSPE-SNVBAGLBSA-N 84635 AI-OH-DP,(-) D(2) dopamine receptor Homo sapiens 486 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339798 136350735 ZINC36438142 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169853 CN1CCc2cccc-3c2[C@@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m0/s1 VMWNQDUVQKEIOC-ZDUSSCGKSA-N 29643 (6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrochloride::(S)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::Apomorphine,(+)::CHEMBL416288::MLS000028867::S(+)-10,11-DIHYDROXYAPORPHINE HYDROCHLORIDE::SMR000058671::US10864248, Compound 1::cid_6852389 D(2) dopamine receptor Homo sapiens 286 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5RL 5ER4 736083 252614855 CHEMBL416288 ZINC02858765 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169854 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 86 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169855 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 19 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169856 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169857 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 1.1 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169858 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50012994 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL538542::NPA,(+)::SKF-76783::cid_11957529 D(2) dopamine receptor Homo sapiens 257 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103925234 CHEMBL538542 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169859 OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22) JXTHEWSKYLZVJC-UHFFFAOYSA-N 81777 CAS_132-66-1::NPA::NPA,(+)::NPA,(-)::NSC_8594 D(2) dopamine receptor Homo sapiens 14 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E7O 7QPC,7WKW,7Y9U 8594 131342351 60833 C06374 ZINC00028113 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 172292 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 10 PDSP Ki 10.1016/0893-133X(94)00129-N 10.7270/Q2445K1M 8822531 Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169860 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Homo sapiens 789 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169861 CCCN1CCc2cccc-3c2[C@@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m0/s1 WZJSIHGOLMMBAL-INIZCTEOSA-N 84632 CAS_132-66-1::NPA-11-OH-R,(-) D(2) dopamine receptor Homo sapiens 68 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13922235 136350732 ZINC05833961 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169862 CCCN1CCO[C@H]2[C@H]1CCc1ccc(O)cc21 InChI=1S/C15H21NO2/c1-2-7-16-8-9-18-15-13-10-12(17)5-3-11(13)4-6-14(15)16/h3,5,10,14-15,17H,2,4,6-9H2,1H3/t14-,15-/m1/s1 JCSREICEMHWFAY-HUUCEWRRSA-N 50020217 (4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol::CHEMBL69271::NAXAGOLIDE HYDROCHLORIDE::PHNO::PHNO,(+) D(2) dopamine receptor Homo sapiens 147 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020217&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57533 103931131 CHEMBL69271 ZINC22064446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169863 CCCN1CCOC2[C@@H]1CCc1ccc(O)cc21 InChI=1S/C15H21NO2/c1-2-7-16-8-9-18-15-13-10-12(17)5-3-11(13)4-6-14(15)16/h3,5,10,14-15,17H,2,4,6-9H2,1H3/t14-,15?/m0/s1 JCSREICEMHWFAY-MLCCFXAWSA-N 84631 CAS_57533::NSC_57533::PHNO,(-) D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84631&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339796 136350731 ZINC26824949 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169864 CCCN1CCC[C@H]2Cc3[nH]ncc3C[C@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m0/s1 FTSUPYGMFAPCFZ-GWCFXTLKSA-N 84634 CAS_54562::NSC_54562::Quinpirole,(+) D(2) dopamine receptor Homo sapiens 5000 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155798 136350734 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169865 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 14 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169866 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 684 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169867 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 38 PDSP Ki 10.1016/0014-2999(93)90365-o 10.7270/Q25D8QBH 8097160 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 172608 C(Oc1cccnc1)[C@@H]1CCN1 InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2/t8-/m0/s1 XKFMBGWHHBCWCD-QMMMGPOBSA-N 50049750 (S)-3-(azetidin-2-ylmethoxy)pyridine::3-((S)-1-Azetidin-2-ylmethoxy)-pyridine::A-159470::A-85380::CHEMBL59986 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/0028-3908(96)84644-2 10.7270/Q237777N 8887981 Sullivan, JP; Donnelly-Roberts, D; Briggs, CA; Anderson, DJ; Gopalakrishnan, M; Piattoni-Kaplan, M; Campbell, JE; McKenna, DG; Molinari, E; Hettinger, AM; Garvey, DS; Wasicak, JT; Holladay, MW; Williams, M; Arneric, SP Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049750&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5310969 103980061 CHEMBL59986 5460 ZINC03805142 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171506 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 30 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171520 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 14 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171521 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 1.3 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171522 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 4.8 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171523 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 420 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171524 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 82 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171525 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 180 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171526 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 9.6 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171527 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.1 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171528 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.8 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171529 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 39 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171530 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 10.1 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171531 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 19 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171532 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Homo sapiens 0.08 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171533 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Homo sapiens 0.01 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171534 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Homo sapiens 0.04 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171535 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 27 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171536 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 1.6 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171537 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 4.5 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171538 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.13 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171539 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.03 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171540 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.06 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171541 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 187 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171542 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 59 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171543 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 137 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171544 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Homo sapiens 0.27 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171545 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Homo sapiens 0.03 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171546 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Homo sapiens 0.06 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171547 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.89 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171548 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.47 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171549 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.63 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171550 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 52 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171551 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 35 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171552 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171553 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 105 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171554 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 500 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171555 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 19 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171556 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 1.6 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171557 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 5.2 PDSP Ki 10.1016/0922-4106(95)90125-6 10.7270/Q2TT4PHV 8566176 Seeman, P; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171668 COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3/t21-/m1/s1 HXTGXYRHXAGCFP-OAQYLSRUSA-N 50095027 (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol (M 100907)::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol(MDL 100907)::(R)-(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol::(R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(R)-(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::(R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol::CHEMBL74355::MDL 100907::MDL-100907 D(2) dopamine receptor Homo sapiens 2250 PDSP Ki 10.7270/Q2FN14R3 8627580 Kehne, JH; Baron, BM; Carr, AA; Chaney, SF; Elands, J; Feldman, DJ; Frank, RA; van Giersbergen, PL; McCloskey, TC; Johnson, MP; McCarty, DR; Poirot, M; Senyah, Y; Siegel, BW; Widmaier, C Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311271 103992797 CHEMBL74355 185 ZINC00598040 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169359 OCC(CN1Cc2ccccc2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H26FN3O2/c24-19-5-6-21-22(11-19)29-25-23(21)16-7-9-27(10-8-16)20(15-28)14-26-12-17-3-1-2-4-18(17)13-26/h1-6,11,16,20,28H,7-10,12-15H2 BVVGNPDCIRMZHQ-UHFFFAOYSA-N 84440 Isoindoline, 7::Isoindoline, 8::Isoindoline, 9 D(2) dopamine receptor Homo sapiens 496 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44215124 136350540 ZINC87722212 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169360 OCC(CN1Cc2ccccc2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H26FN3O2/c24-19-5-6-21-22(11-19)29-25-23(21)16-7-9-27(10-8-16)20(15-28)14-26-12-17-3-1-2-4-18(17)13-26/h1-6,11,16,20,28H,7-10,12-15H2 BVVGNPDCIRMZHQ-UHFFFAOYSA-N 84440 Isoindoline, 7::Isoindoline, 8::Isoindoline, 9 D(2) dopamine receptor Homo sapiens 134 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44215124 136350540 ZINC87722212 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169361 OCC(CN1Cc2ccccc2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H26FN3O2/c24-19-5-6-21-22(11-19)29-25-23(21)16-7-9-27(10-8-16)20(15-28)14-26-12-17-3-1-2-4-18(17)13-26/h1-6,11,16,20,28H,7-10,12-15H2 BVVGNPDCIRMZHQ-UHFFFAOYSA-N 84440 Isoindoline, 7::Isoindoline, 8::Isoindoline, 9 D(2) dopamine receptor Homo sapiens 777 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44215124 136350540 ZINC87722212 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169362 OCC(CN1Cc2ccc(F)cc2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H25F2N3O2/c24-18-2-1-16-11-27(12-17(16)9-18)13-20(14-29)28-7-5-15(6-8-28)23-21-4-3-19(25)10-22(21)30-26-23/h1-4,9-10,15,20,29H,5-8,11-14H2 YCHBCAZCQRJJQZ-UHFFFAOYSA-N 84443 Isoindoline, 10::Isoindoline, 11 D(2) dopamine receptor Homo sapiens 100 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339693 136350543 ZINC87722217 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169363 OCC(CN1Cc2ccc(F)cc2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H25F2N3O2/c24-18-2-1-16-11-27(12-17(16)9-18)13-20(14-29)28-7-5-15(6-8-28)23-21-4-3-19(25)10-22(21)30-26-23/h1-4,9-10,15,20,29H,5-8,11-14H2 YCHBCAZCQRJJQZ-UHFFFAOYSA-N 84443 Isoindoline, 10::Isoindoline, 11 D(2) dopamine receptor Homo sapiens 250 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339693 136350543 ZINC87722217 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169364 OCC(CN1Cc2cccc(F)c2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H25F2N3O2/c24-17-4-5-19-22(10-17)30-26-23(19)15-6-8-28(9-7-15)18(14-29)12-27-11-16-2-1-3-21(25)20(16)13-27/h1-5,10,15,18,29H,6-9,11-14H2 XPQFMRCQDNWUBC-UHFFFAOYSA-N 84445 Isoindoline, 12 D(2) dopamine receptor Homo sapiens 55.9 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339694 136350545 ZINC87722220 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169365 OCC(CN1Cc2ccc(Cl)cc2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H25ClFN3O2/c24-18-2-1-16-11-27(12-17(16)9-18)13-20(14-29)28-7-5-15(6-8-28)23-21-4-3-19(25)10-22(21)30-26-23/h1-4,9-10,15,20,29H,5-8,11-14H2 KAVSHSNHZGLMBP-UHFFFAOYSA-N 84446 Isoindoline, 13 D(2) dopamine receptor Homo sapiens 120 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339695 136350546 ZINC89455448 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169366 OCC(CN1Cc2cc(Cl)c(Cl)cc2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H24Cl2FN3O2/c24-20-7-15-10-28(11-16(15)8-21(20)25)12-18(13-30)29-5-3-14(4-6-29)23-19-2-1-17(26)9-22(19)31-27-23/h1-2,7-9,14,18,30H,3-6,10-13H2 IEFNCANDVITLIP-UHFFFAOYSA-N 84447 Isoindoline, 14 D(2) dopamine receptor Homo sapiens 302 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339696 136350547 ZINC87722223 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169367 Cc1ccc2CN(CC(CO)N3CCC(CC3)c3noc4cc(F)ccc34)Cc2c1 InChI=1S/C24H28FN3O2/c1-16-2-3-18-12-27(13-19(18)10-16)14-21(15-29)28-8-6-17(7-9-28)24-22-5-4-20(25)11-23(22)30-26-24/h2-5,10-11,17,21,29H,6-9,12-15H2,1H3 MUXRCMBCLRYUGM-UHFFFAOYSA-N 84448 Isoindoline, 15 D(2) dopamine receptor Homo sapiens 188 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339697 136350548 ZINC89455455 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169368 Cc1cccc2CN(CC(CO)N3CCC(CC3)c3noc4cc(F)ccc34)Cc12 InChI=1S/C24H28FN3O2/c1-16-3-2-4-18-12-27(14-22(16)18)13-20(15-29)28-9-7-17(8-10-28)24-21-6-5-19(25)11-23(21)30-26-24/h2-6,11,17,20,29H,7-10,12-15H2,1H3 HTUYABQWSXGCMY-UHFFFAOYSA-N 84449 Isoindoline, 16 D(2) dopamine receptor Homo sapiens 185 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339698 136350549 ZINC87722227 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169369 OCC(CN1Cc2ccc(cc2C1)C(F)(F)F)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C24H25F4N3O2/c25-19-3-4-21-22(10-19)33-29-23(21)15-5-7-31(8-6-15)20(14-32)13-30-11-16-1-2-18(24(26,27)28)9-17(16)12-30/h1-4,9-10,15,20,32H,5-8,11-14H2 QRWILOLSJSALOC-UHFFFAOYSA-N 84450 Isoindoline, 17 D(2) dopamine receptor Homo sapiens 501 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339699 136350550 ZINC89455465 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169370 COc1ccc2CN(CC(CO)N3CCC(CC3)c3noc4cc(F)ccc34)Cc2c1 InChI=1S/C24H28FN3O3/c1-30-21-4-2-17-12-27(13-18(17)10-21)14-20(15-29)28-8-6-16(7-9-28)24-22-5-3-19(25)11-23(22)31-26-24/h2-5,10-11,16,20,29H,6-9,12-15H2,1H3 ONBNKWWUQSJKER-UHFFFAOYSA-N 84451 Isoindoline, 18::Isoindoline, 19 D(2) dopamine receptor Homo sapiens 392 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339700 136350551 ZINC87722231 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169371 COc1ccc2CN(CC(CO)N3CCC(CC3)c3noc4cc(F)ccc34)Cc2c1 InChI=1S/C24H28FN3O3/c1-30-21-4-2-17-12-27(13-18(17)10-21)14-20(15-29)28-8-6-16(7-9-28)24-22-5-3-19(25)11-23(22)31-26-24/h2-5,10-11,16,20,29H,6-9,12-15H2,1H3 ONBNKWWUQSJKER-UHFFFAOYSA-N 84451 Isoindoline, 18::Isoindoline, 19 D(2) dopamine receptor Homo sapiens 3527 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339700 136350551 ZINC87722231 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169372 COc1cccc2CN(CC(CO)N3CCC(CC3)c3noc4cc(F)ccc34)Cc12 InChI=1S/C24H28FN3O3/c1-30-22-4-2-3-17-12-27(14-21(17)22)13-19(15-29)28-9-7-16(8-10-28)24-20-6-5-18(25)11-23(20)31-26-24/h2-6,11,16,19,29H,7-10,12-15H2,1H3 OUBHWPADUALDCK-UHFFFAOYSA-N 84453 Isoindoline, 20 D(2) dopamine receptor Homo sapiens 203 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339701 136350553 ZINC87722235 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169373 OCC(CN1Cc2ccccc2C1=O)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H24FN3O3/c24-17-5-6-20-21(11-17)30-25-22(20)15-7-9-26(10-8-15)18(14-28)13-27-12-16-3-1-2-4-19(16)23(27)29/h1-6,11,15,18,28H,7-10,12-14H2 CAMCAPPHFSFXSO-UHFFFAOYSA-N 84456 Isoindoline, 23 D(2) dopamine receptor Homo sapiens 341 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339704 136350556 ZINC89455477 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169374 OCC(CN1C(=O)[C@H]2CCCC[C@H]2C1=O)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H28FN3O4/c24-15-5-6-19-20(11-15)31-25-21(19)14-7-9-26(10-8-14)16(13-28)12-27-22(29)17-3-1-2-4-18(17)23(27)30/h5-6,11,14,16-18,28H,1-4,7-10,12-13H2/t16?,17-,18+ RFPRZRMMLBXENH-AYHJJNSGSA-N 84457 Isoindoline, 24 D(2) dopamine receptor Homo sapiens 6912 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339705 136350557 ZINC87722244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169375 OCC(CN1C(=C)[C@@H]2CCCC[C@@H]2C1=O)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C24H30FN3O3/c1-15-19-4-2-3-5-20(19)24(30)28(15)13-18(14-29)27-10-8-16(9-11-27)23-21-7-6-17(25)12-22(21)31-26-23/h6-7,12,16,18-20,29H,1-5,8-11,13-14H2/t18?,19-,20-/m0/s1 JOEBPYFHQSFJJM-YPJRHXLCSA-N 84458 Isoindoline, 25 D(2) dopamine receptor Homo sapiens >1000 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339706 136350558 ZINC89455481 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 169376 OCC(CN1CCc2ccccc2C1)N1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C24H28FN3O2/c25-20-5-6-22-23(13-20)30-26-24(22)18-8-11-28(12-9-18)21(16-29)15-27-10-7-17-3-1-2-4-19(17)14-27/h1-6,13,18,21,29H,7-12,14-16H2 AJTFQQUHXJLYJZ-UHFFFAOYSA-N 84459 Isoindoline, 26 D(2) dopamine receptor Homo sapiens 120 Curated from the literature by BindingDB 10.1002/1439-7633(20021004)3:10 10.7270/Q27D2SP5 12362366 aid1799610 Hendrix, JA; Shimshock, SJ; Shutske, GM; Tomer, JD; Kapples, KJ; Palermo, MG; Corbett, TJ; Vargas, HM; Kafka, S; Brooks, KM; Laws-Ricker, L; Lee, DK; de Lannoy, I; Bordeleau, M; Rizkalla, G; Owolabi, J; Kamboj, RK Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339707 136350559 ZINC87722248 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 171891 CC(N)Cc1c[nH]c2ccc(OCc3cccs3)cc12 InChI=1S/C16H18N2OS/c1-11(17)7-12-9-18-16-5-4-13(8-15(12)16)19-10-14-3-2-6-20-14/h2-6,8-9,11,18H,7,10,17H2,1H3 ALFGDCNSEBJYSP-UHFFFAOYSA-N 82472 BW-723C86::CAS_5311036::NSC_5311036 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1111/j.1476-5381.1996.tb15304.x 10.7270/Q2DN43K8 8730737 Kennett, GA; Bright, F; Trail, B; Baxter, GS; Blackburn, TP SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4284720 136350443 ZINC03995822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 172121 Cn1ccc2cc(NC(=O)Nc3cccnc3)ccc12 InChI=1S/C15H14N4O/c1-19-8-6-11-9-12(4-5-14(11)19)17-15(20)18-13-3-2-7-16-10-13/h2-10H,1H3,(H2,17,18,20) OJZZJTLBYXHUSJ-UHFFFAOYSA-N 82272 SB 200646::SB200646a D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/0166-4328(96)00087-3 10.7270/Q2RX99ND 8788493 Baxter, GS SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126769 136350244 C11739 ZINC00005475 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 172122 Cc1cc(NC(=O)Nc2ccc3n(C)ccc3c2)sn1 InChI=1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19) USFUFHFQWXDVMH-UHFFFAOYSA-N 84991 CAS_3277600::NSC_3277600::SB204741 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/0166-4328(96)00087-3 10.7270/Q2RX99ND 8788493 Baxter, GS SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3277600 136351091 221 ZINC00016912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175916 C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1cccc(C)c1 InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1 AGVNHDNTFYHZNL-QGZVFWFLSA-N 50098550 3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide::3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide::3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide (SB-258719)::4-Methyl-1-[(R)-3-methyl-4-(toluene-3-sulfonyl)-pentyl]-piperidine::CHEMBL12264::SB-258719 D(2) dopamine receptor Homo sapiens 3981.07 PDSP Ki 10.1021/jm970519e 10.7270/Q2GX4949 9513592 Forbes, IT; Dabbs, S; Duckworth, DM; Jennings, AJ; King, FD; Lovell, PJ; Brown, AM; Collin, L; Hagan, JJ; Middlemiss, DN; Riley, GJ; Thomas, DR; Upton, N SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5312148 103995563 CHEMBL12264 281 ZINC00007275 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173544 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 291 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173545 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.3 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173546 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 XMXHEBAFVSFQEX-UHFFFAOYSA-N 50034043 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE D(2) dopamine receptor Homo sapiens 6.3 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71360 103942259 65173 CHEMBL14376 DB04946 87 ZINC01548097 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173547 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 37.7 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173548 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 706 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173549 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 2.7 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173550 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 168 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173551 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.1 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173552 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 XMXHEBAFVSFQEX-UHFFFAOYSA-N 50034043 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE D(2) dopamine receptor Homo sapiens 13.3 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71360 103942259 65173 CHEMBL14376 DB04946 87 ZINC01548097 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173553 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 30.3 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173554 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 779 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173555 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 3.3 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173625 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 0.66 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173626 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 44 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173627 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Homo sapiens 0.32 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173628 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.35 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173629 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Homo sapiens 5.8 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173630 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 5.2 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173631 CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 DKMFBWQBDIGMHM-UHFFFAOYSA-N 81771 CAS_3575-80-2::MELPERONE::NSC_15387 D(2) dopamine receptor Homo sapiens 88 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15387 131342345 DB09224 ZINC00001672 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173632 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Homo sapiens 6 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173633 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 3.7 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173634 CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12 InChI=1S/C19H21N3/c1-21-10-12-22(13-11-21)19-17-8-4-2-6-15(17)14-16-7-3-5-9-18(16)20-19/h2-9H,10-14H2,1H3 PWRPUAKXMQAFCJ-UHFFFAOYSA-N 50102325 6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::CHEMBL340801::Perlapine D(2) dopamine receptor Homo sapiens 60 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16106 103998865 CHEMBL340801 ZINC27303430 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173635 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 78 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173636 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Homo sapiens 0.64 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173637 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Homo sapiens 30 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173638 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 0.3 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173639 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 0.95 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173640 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 0.4 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173641 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Homo sapiens 0.96 PDSP Ki 10.1016/S0893-133X(96)00187-X 10.7270/Q2513WR8 9015795 Seeman, P; Corbett, R; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177465 Cc1[nH]c2ccc(O)cc2c1CCN InChI=1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3 WYWNEDARFVJQSG-UHFFFAOYSA-N 50014406 2-Me 5-HT::2-Methyl-5-hydroxytryptamine::2-methyl-5-HT::2-methylserotonin::3-(2-aminoethyl)-2-methyl-1H-indol-5-ol::5-HT,2-Me::CHEMBL266591 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014406&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1574 103926391 31085 CHEMBL266591 218 C13665 ZINC02572146 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177466 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177467 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Homo sapiens 1788 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177468 CC(N)Cc1ccccc1 InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3 KWTSXDURSIMDCE-UHFFFAOYSA-N 50005246 1-Phenylpropan-2-amin::1-phenyl-2-aminopropane::1-phenylpropan-2-amine::AMP ASPARTATE::AMPHETAMINE::AMPHETAMINE SULFATE::Amfetamine::Amphetamin::DEXTROAMP SACCHARATE::alpha-methylbenzeneethaneamine::alpha-methylphenylethylamine::amfetaminum::beta-Phenylisopropylamin::beta-aminopropylbenzene::beta-phenylisopropylamine::desoxynorephedrine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1WE 2AOJ,2AOH,2AOI,2AOF 3007 103918755 2679 DB00182 4804 C07514 ZINC06036847 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177469 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 42 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177470 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 8.2 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177471 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177472 NC(=O)N1c2ccccc2C=Cc2ccccc12 InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18) FFGPTBGBLSHEPO-UHFFFAOYSA-N 50003659 5H-dibenzo[b,f]azepine-5-carboxamide::CARBAMAZEPINE::CARBATROL::CHEMBL108::DIBENZO[B,F]AZEPINE-5-CARBOXYLIC ACID AMIDE(CARBAMAZEPINE)::EPITOL::EQUETRO::G-32883::TEGRETOL::TEGRETOL-XR::TERIL::US9138393, Carbamazepine::US9144538, Carbamazepine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003659&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search N6W 6TFB 2554 103917593 3387 CHEMBL108 DB00564 5339 C06868 ZINC00004785 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177473 CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F InChI=1S/C17H17F3N4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16/h2-6,11H,7-10H2,1H3 LXFHSCDLMBZYKY-UHFFFAOYSA-N 81497 4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline::CAS_109028-10-6::CGS 12066B::CHEMBL27403::NSC_123945 D(2) dopamine receptor Homo sapiens 1739 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2689 131342071 CHEMBL27403 ZINC02516018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177474 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 3 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177475 CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12 InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 GDLIGKIOYRNHDA-UHFFFAOYSA-N 77970 3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-1-propanamine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-dimethyl-amine;hydrochloride::CHLORIMIPRAMINE::CLOMIPRAMINE::CLOMIPRAMINE HYDROCHLORIDE::CLOMIPRIMINE::MLS000028511::SMR000058295::cid_68539::med.21724, Compound Clomipramine D(2) dopamine receptor Homo sapiens 162 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search CXX 4MMA,2QEI,6G9I,2Q6H 2801 252654733 3755 DB01242 C06918 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177476 COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1OC(=O)c1ccccc1)N2C InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 22418 Cocaine::Cocaine (-)::methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate::methyl (1R,2R,3S,5S)-8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-carboxylate D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search COC 1I7Z,1Q72,2AJV,4XP4,4XPB,2PGZ 446220 49846233 27958 DB00907 2286 C01416 ZINC03875336 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177477 CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12 InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3 JJCFRYNCJDLXIK-UHFFFAOYSA-N 50017721 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine::1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine::4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine::4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine::4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine::5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene::CHEMBL516::CYPROHEPTADINE D(2) dopamine receptor Homo sapiens 112 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search C7H 5AYF 2913 103928989 4046 CHEMBL516 DB00434 277 C06935 ZINC00968264 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177478 C[C@H](Cc1ccccc1)N(C)CC#C InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1 MEZLKOACVSPNER-GFCCVEGCSA-N 15579 CHEMBL972::DEPRENYL::L-Deprenyl::N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine::SLG::Selegiline::US8633208, Deprenyl::US9469653, Selegiline::methyl[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-ylamine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=15579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 26757 46509459 50217 CHEMBL972 6639 C07245 ZINC19632633 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177479 CNCCCN1c2ccccc2CCc2ccccc12 InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3 HCYAFALTSJYZDH-UHFFFAOYSA-N 35229 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine::5-(gamma-methylaminopropyl)iminodibenzyl::CHEMBL72::DESIPRAMINE HYDROCHLORIDE::DMI::Desipramin::Desipramine::Desmethylimipramine::N-(3-methylaminopropyl)iminobibenzyl::US9944618, Compound ID No. 174::demethylimipramine::monodemethylimipramine::norimipramine D(2) dopamine receptor Homo sapiens 1561 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35229&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search DSM 7Q19,2QJU,7Q2N,7Q2O,7Q2P,2QB4 2995 85753308 47781 CHEMBL72 DB01151 2399 C06943 ZINC01530611 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177480 CN1CC(CC2C1Cc1c[nH]c3cccc2c13)C(=O)N[C@]1(C)O[C@@]2(O)C3CCCN3C(=O)[C@H](Cc3ccccc3)N2C1=O InChI=1S/C33H37N5O5/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39)/t21?,23?,25?,26-,27?,32+,33-/m0/s1 LUZRJRNZXALNLM-YCFDMHLDSA-N 50280055 50285557::7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((2R,5S,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::DHE D(2) dopamine receptor Homo sapiens 5 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280055&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44272242 104121759 ZINC44182236 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177481 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 422 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177482 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Homo sapiens 0.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177483 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Homo sapiens 1.5 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177484 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Homo sapiens 0.9 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177485 Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2 NAUWTFJOPJWYOT-UHFFFAOYSA-N 22165 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine::CHEMBL153260::CHEMBL281594::CHEMBL542933::CHEMBL543876::GBR 12909::GBR-12909::NCGC00015300::US9944618, Compound ID No. 175::Vanoxerine D(2) dopamine receptor Homo sapiens 737 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3455 49845980 64089 CHEMBL153260CHEMBL281594CHEMBL543876CHEMBL542933 ZINC22034135 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177486 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.5 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177487 CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(OC)cc12 InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12?,13-,17-,20?/m1/s1 HSIBGVUMFOSJPD-XTKBRTNLSA-N 50067812 17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraen-7-yl methyl ether (ibogaine)::CHEMBL140939::IBOGAINE D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44359514 103962238 CHEMBL140939 ZINC04556587 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177488 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3 ZNRGQMMCGHDTEI-UHFFFAOYSA-N 50007871 CHEMBL8197::ICS 205-930::TROPISETRON D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TKT 6HIS,2WNC,5OAJ 5595 103921139 CHEMBL8197 C02089 ZINC18130447 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177489 C1CN=C(N1)C1COc2ccccc2O1 InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) HPMRFMKYPGXPEP-UHFFFAOYSA-N 50019848 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54459 103930771 5862 CHEMBL10316 C10968 ZINC00900630 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177490 CN(C)CCCN1c2ccccc2CCc2ccccc12 InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 BCGWQEUPMDMJNV-UHFFFAOYSA-N 50010859 CHEMBL11::IMIPRAMINE HYDROCHLORIDE::IMIPRAMINE PAMOATE::Imipramin D(2) dopamine receptor Homo sapiens 726 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search IXX 2Q72,7LWD,6G9B 3696 103923605 47499 CHEMBL11 DB00458 357 C07049 ZINC00020245 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177491 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177492 NC(Cc1ccc(O)c(O)c1)C(O)=O InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14) WTDRDQBEARUVNC-UHFFFAOYSA-N 4377 2-amino-3-(3,4-dihydroxyphenyl)propanoic acid::DOPA::L-DOPA D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search DAH 2VH3,5XDH,6PAH,2ZWE,2ZWG,2ZWF,1IVV,1RNR,6EBP,6EBZ,6JU5,6JU4,6JU9,4P6S,5Z0I,5Z0H,5Z0K,5Z0J,5Z0M,5Z0L,5Z0G,5Z0F,6ON3,4EIS,6GP2,3TEG,3TEH 836 8034053 49168 ZINC01506908 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177493 CC(N)Cc1ccc2OCOc2c1 InChI=1S/C10H13NO2/c1-7(11)4-8-2-3-9-10(5-8)13-6-12-9/h2-3,5,7H,4,6,11H2,1H3 NGBBVGZWCFBOGO-UHFFFAOYSA-N 50005247 (+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::(-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::(R)-(-)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::(S)-(+)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine((R)-(-)-MDA)::3,4-methylenedioxyamphetamine::CHEMBL6731::MDA::MDA, (R,S)::MDA,R(-)::Tenamfetamine::methylenedioxyamphetamine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1614 103918756 CHEMBL6731 DB01509 ZINC00403033 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177494 CN1C2CCC1CC(C2)OC(=O)c1cc(Cl)cc(Cl)c1 InChI=1S/C15H17Cl2NO2/c1-18-12-2-3-13(18)8-14(7-12)20-15(19)9-4-10(16)6-11(17)5-9/h4-6,12-14H,2-3,7-8H2,1H3 MNJNPLVXBISNSX-UHFFFAOYSA-N 50241143 (MDL 72222)3,5-Dichloro-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3,5-Dichloro-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3,5-Dichloro-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester (MDL 72222)::3,5-Dichloro-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester(MDL 72222)::3,5-Dichloro-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester(MDL-72222)::3,5-Dichloro-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester(MDL72222)::3alpha-(3',5'-dichlorobenzoyloxy)tropane::CHEMBL376379::MDL 72222::MDL-72222::[2-(5-Hydroxy-1H-indol-3-yl)-ethyl]-trimethyl-ammonium D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241143&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1683 104098625 CHEMBL376379 C02089 ZINC00033131 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177495 CN[C@@H](C)Cc1ccc2OCOc2c1 InChI=1S/C11H15NO2/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10/h3-4,6,8,12H,5,7H2,1-2H3/t8-/m0/s1 SHXWCVYOXRDMCX-QMMMGPOBSA-N 85332 MDMA, R(-) D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search B41 3GM0 854031 136351432 1391 C07577 ZINC00000859 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177496 CNC(C)Cc1ccccc1 InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3 MYWUZJCMWCOHBA-UHFFFAOYSA-N 50009057 (R)Methyl-(1-methyl-2-phenyl-ethyl)-amine::METHAMPHETAMINE::METHAMPHETAMINE (+)::METHAMPHETAMINE (-)::Methyl-(1-methyl-2-phenyl-ethyl)-amine::Methyl-(1-methyl-2-phenyl-ethyl)-amine(methamphetamine) D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009057&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search B40 3GKZ,4GQP,4XP6 1206 103922115 ZINC08466459 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177497 COC(=O)[C@H]([C@@H]1CCCCN1)c1ccccc1 InChI=1S/C14H19NO2/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3/t12-,13-/m0/s1 DUGOZIWVEXMGBE-STQMWFEESA-N 50050098 (S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl ester; hydrochloride::CHEMBL542556::METHYLPHENIDATE D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050098&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10657292 103947285 CHEMBL542556 C07196 ZINC02522648 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177498 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Homo sapiens 64 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177499 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Homo sapiens 1274 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173668 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Homo sapiens 0.32 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173669 Nc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H27N5OS/c23-19-9-3-1-7-17(19)22(28)24-11-5-6-12-26-13-15-27(16-14-26)21-18-8-2-4-10-20(18)29-25-21/h1-4,7-10H,5-6,11-16,23H2,(H,24,28) GMDXHLCLNHCEIC-UHFFFAOYSA-N 85048 CHEMBL537481::Glaxo 1192U90 D(2) dopamine receptor Homo sapiens 4 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127912 136351148 CHEMBL537481 ZINC01537573 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173670 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173674 [NH3+][C@@H]1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2/p+1/t8-/m1/s1 ASXGAOFCKGHGMF-MRVPVSSYSA-O 50091032 6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-ammonium(R(+)ADTN)::Aminotetralin-6,7-dihydroxy-(+) D(2) dopamine receptor Homo sapiens 4200 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332855 103989453 ZINC03872369 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173677 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 4300 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173679 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 110 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173682 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 400 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173685 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 2500 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173687 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 880 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173692 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 60 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173699 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173701 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Homo sapiens 3200 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173703 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Homo sapiens 15 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173705 NCC(O)c1ccc(O)c(O)c1 InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 SFLSHLFXELFNJZ-UHFFFAOYSA-N 35234 DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE D(2) dopamine receptor Homo sapiens 3130 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LNR 3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH 951 85753313 33569 484 ZINC00057624 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173707 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 800 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176186 Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1 InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2 QWGDMFLQWFTERH-UHFFFAOYSA-N 22870 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine::Amoxapine::Asendin::CHEMBL1113::Demolox D(2) dopamine receptor Homo sapiens 16 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2170 49846684 2675 CHEMBL1113 DB00543 201 ZINC00000931 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176187 Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O InChI=1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) FEBOTPHFXYHVPL-UHFFFAOYSA-N 81492 BENPERIDOL::CAS_2062-84-2::NSC_16363 D(2) dopamine receptor Homo sapiens 0.027 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16363 131342066 ZINC19144237 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176188 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 2 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176189 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.05 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176190 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 0.66 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176191 CN(C)CC\C=C1/c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7+ WSPOMRSOLSGNFJ-VGOFMYFVSA-N 50130257 (3E)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine::(E)-chlorprothixene::CHEMBL90125::CHLORPROTHIXENE::Chlorprothixene (cis) D(2) dopamine receptor Homo sapiens 3.3 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 667466 104021691 50932 CHEMBL90125 ZINC31261349 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176192 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 44 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176193 Fc1ccc(cc1)C(=O)CCCN1CCC(=CC1)n1c2ccccc2[nH]c1=O InChI=1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28) RMEDXOLNCUSCGS-UHFFFAOYSA-N 50017705 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-{1-[4-(4-Chloro-phenyl)-4-oxo-butyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Droperidol)::1-{1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl}-2,3-dihydro-1H-benzo[d]imidazol-2-one::CHEMBL1108::DROPERIDOL::Inapsine::McN-JR-4749::R-4749 D(2) dopamine receptor Homo sapiens 0.25 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017705&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search USS 6X6G 3168 103928973 4717 CHEMBL1108 DB00450 7172 ZINC19796080 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176194 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Homo sapiens 0.01 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176195 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.35 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176196 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 XMXHEBAFVSFQEX-UHFFFAOYSA-N 50034043 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE D(2) dopamine receptor Homo sapiens 0.35 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71360 103942259 65173 CHEMBL14376 DB04946 87 ZINC01548097 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176197 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Homo sapiens 6 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176198 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Oc2ccccc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-7-6-13(19)12-15(17)20-18/h2-7,12H,8-11H2,1H3 AWHNHDGHHNGACT-UHFFFAOYSA-N 50028980 8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine::8-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::CHEMBL7828::Isoloxapine D(2) dopamine receptor Homo sapiens 6 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028980&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381810 103938110 CHEMBL7828 ZINC13532241 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176199 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 5.2 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176200 COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3/t21-/m1/s1 HXTGXYRHXAGCFP-OAQYLSRUSA-N 50095027 (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol (M 100907)::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol(MDL 100907)::(R)-(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol::(R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(R)-(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::(R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol::CHEMBL74355::MDL 100907::MDL-100907 D(2) dopamine receptor Homo sapiens 9000 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311271 103992797 CHEMBL74355 185 ZINC00598040 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176201 CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 DKMFBWQBDIGMHM-UHFFFAOYSA-N 81771 CAS_3575-80-2::MELPERONE::NSC_15387 D(2) dopamine receptor Homo sapiens 50 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15387 131342345 DB09224 ZINC00001672 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177500 COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3 SJDOMIRMMUGQQK-UHFFFAOYSA-N 82517 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione::CAS_107966::CHEMBL126632::CHEMBL8618::NAN-190::NSC_107966 D(2) dopamine receptor Homo sapiens 47 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4431 136350487 64123 CHEMBL8618CHEMBL126632 ZINC01537496 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173714 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173715 CN1C[C@H](CSc2ccccn2)C[C@@H]2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C20H24N2OS/c1-22-12-14(13-24-20-7-2-3-8-21-20)9-16-10-17-15(11-18(16)22)5-4-6-19(17)23/h2-8,14,16,18,23H,9-13H2,1H3/t14-,16-,18-/m1/s1 OZUQRMYHPWAQQC-QGPMSJSTSA-N 85047 SDZ GLC 756 D(2) dopamine receptor Homo sapiens 75 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840900 136351147 ZINC03826945 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173717 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 15 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173720 CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1 BGRJTUBHPOOWDU-LLVKDONJSA-N 81775 Sulpiride-R::Sulpiride-d::Sulpiride-high,(-)::Sulpiride-low,(-) D(2) dopamine receptor Homo sapiens 4634 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 643497 131342349 64122 960 ZINC00020229 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173723 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Homo sapiens 3326 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175083 NC(=O)c1ccc(F)c2OCC(Cc12)N(C1CCC1)C1CCC1 InChI=1S/C18H23FN2O2/c19-16-8-7-14(18(20)22)15-9-13(10-23-17(15)16)21(11-3-1-4-11)12-5-2-6-12/h7-8,11-13H,1-6,9-10H2,(H2,20,22) MQTUXRKNJYPMCG-UHFFFAOYSA-N 85190 CAS_3055171::NAD-299::NSC_3055171 D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.7270/Q22Z142T 9336327 Johansson, L; Sohn, D; Thorberg, SO; Jackson, DM; Kelder, D; Larsson, LG; Renyi, L; Ross, SB; Wallsten, C; Eriksson, H; Hu, PS; Jerning, E; Mohell, N; Westlind-Danielsson, A Preclinical R & D, Astra Arcus AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85190&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12016890 136351290 82 ZINC04631259 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175084 COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3 SBPRIAGPYFYCRT-UHFFFAOYSA-N 86708 CAS_146714-97-8::CHEMBL31354::CHEMBL514874::CHEMBL537403::NSC_104911::WAY 100,635 D(2) dopamine receptor Homo sapiens 79 PDSP Ki 10.7270/Q22Z142T 9336327 Johansson, L; Sohn, D; Thorberg, SO; Jackson, DM; Kelder, D; Larsson, LG; Renyi, L; Ross, SB; Wallsten, C; Eriksson, H; Hu, PS; Jerning, E; Mohell, N; Westlind-Danielsson, A Preclinical R & D, Astra Arcus AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86708&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5684 136352757 CHEMBL537403CHEMBL514874CHEMBL31354 ZINC52541473 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176202 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Homo sapiens 6 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176203 Cc1ccc(cc1)C1(O)CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C22H26FNO2/c1-17-4-8-19(9-5-17)22(26)12-15-24(16-13-22)14-2-3-21(25)18-6-10-20(23)11-7-18/h4-11,26H,2-3,12-16H2,1H3 AGAHNABIDCTLHW-UHFFFAOYSA-N 81486 CAS_1050-79-9::MOPERONE::NSC_4249 D(2) dopamine receptor Homo sapiens 1.8 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4249 131342060 ZINC00538026 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176204 Clc1ccc2N=c3ccccc3=C(Nc2c1)N1CCNCC1 InChI=1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19,21H,7-10H2 HESZUPIXRNZIOI-UHFFFAOYSA-N 82478 CAS_2820::N-DESMETHYLCLOZAPINE::NSC_2820 D(2) dopamine receptor Homo sapiens 100 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82478&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2820 136350449 333 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176205 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 3 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176206 CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12 InChI=1S/C19H21N3/c1-21-10-12-22(13-11-21)19-17-8-4-2-6-15(17)14-16-7-3-5-9-18(16)20-19/h2-9H,10-14H2,1H3 PWRPUAKXMQAFCJ-UHFFFAOYSA-N 50102325 6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::CHEMBL340801::Perlapine D(2) dopamine receptor Homo sapiens 60 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16106 103998865 CHEMBL340801 ZINC27303430 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176207 O=C1C2CCCCC2C(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H30N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h3-4,9-10,17-18H,1-2,5-8,11-16H2 FBVFZWUMDDXLLG-UHFFFAOYSA-N 85223 CAS_115368::NSC_115368::Perospirone D(2) dopamine receptor Homo sapiens 0.6 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85223&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14096625 136351323 ZINC13828184 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176208 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 RGCVKNLCSQQDEP-UHFFFAOYSA-N 50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine D(2) dopamine receptor Homo sapiens 0.16 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4748 104021707 8028 CHEMBL567 DB00850 209 C07427 ZINC19228902 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176209 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 0.6 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176210 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 78434 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499 D(2) dopamine receptor Homo sapiens 1.2 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P77 3M0W 4917 252655190 8435 DB00433 C07403 ZINC19796018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176211 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 78 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176212 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Homo sapiens 0.64 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176213 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Homo sapiens 30 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176214 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 0.3 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176215 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Homo sapiens 10 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176216 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 2.6 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176217 O=C1[C@H]2[C@@H]3CC[C@@H](C3)[C@H]2C(=O)N1C[C@@H]1CCCC[C@H]1CN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C28H36N4O2S/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2/t18-,19+,20-,21-,24+,25-/m0/s1 PQXKDMSYBGKCJA-CVTJIBDQSA-N 85222 CAS_441351-20-8::Lurasidone::SM 13496 D(2) dopamine receptor Homo sapiens 1.2 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 213046 136351322 70735 DB08815 ZINC33974796 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176218 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Homo sapiens 5 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176219 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 0.4 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176220 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- GFBKORZTTCHDGY-UWVJOHFNSA-N 78576 CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene D(2) dopamine receptor Homo sapiens 0.12 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941651 252655323 DB01623 212 ZINC30690433 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176221 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Homo sapiens 0.96 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 176222 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 1.2 PDSP Ki 10.1038/sj.mp.4000336 10.7270/Q2G15ZCQ 9577836 Seeman, P; Tallerico, T University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177501 CN1CC(c2ccccc2)c2cccc(N)c2C1 InChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3 XXPANQJNYNUNES-UHFFFAOYSA-N 50005548 (+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(Nomifensine) 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine (Nomifensine)::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine(Nomifensine)::2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine::CHEMBL273575::NOMIFENSINE::NOMIFENSINE2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4528 103919027 116225 CHEMBL273575 DB04821 4792 ZINC19796035 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177502 NCC(O)c1ccc(O)c(O)c1 InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 SFLSHLFXELFNJZ-UHFFFAOYSA-N 35234 DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LNR 3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH 951 85753313 33569 484 ZINC00057624 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177503 Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 FELGMEQIXOGIFQ-UHFFFAOYSA-N 85330 CAS_68647::NSC_68647::ONDANSETRON::Ondansetron hydrochloride D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search S87 6W1M 4595 136351430 DB00904 C07325 ZINC00075126 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177504 Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19) MRBDMNSDAVCSSF-UHFFFAOYSA-N 31046 3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5775 252615298 DB00692 ZINC00020251 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177505 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 2.2 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177506 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Homo sapiens 192 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177507 CC(C)NCC(O)COc1cccc2ccccc12 InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3 AQHHHDLHHXJYJD-UHFFFAOYSA-N 25761 Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SNP 1DY4,6EKZ,6PS5,5FUK 4946 56413049 8499 CHEMBL27 DB00571 564 C07407 ZINC00056556 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177508 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 1185 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177509 C1CN(CCN1)c1ccc2ccccc2n1 InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2 XRXDAJYKGWNHTQ-UHFFFAOYSA-N 50014407 2-(piperazin-1-yl)quinoline::2-Piperazin-1-yl-quinoline::2-Piperazin-1-yl-quinoline (Quipazine)::2-Piperazin-1-yl-quinoline(Quipazine)::CHEMBL18772::QUIPAZINE D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014407&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5011 103926392 CHEMBL18772 173 ZINC19376338 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177510 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c1cc(OC)c(OC)c(OC)c1 InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1 QEVHRUUCFGRFIF-MDEJGZGSSA-N 50017712 (-)-reserpine::(3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester::3,4,5-trimethoxybenzoyl methyl reserpate::Apoplon::CHEMBL772::NCGC00091250::RESERPINE::Reserpin::Serpalan::cid_5770::methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate D(2) dopamine receptor Homo sapiens 586 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5770 103928980 28487 CHEMBL772 DB00206 4823 C06539 ZINC03938746 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177511 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Homo sapiens 84 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177512 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Homo sapiens 431 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177513 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177514 Oc1cc2CCN(CC=C)CC(c3ccccc3)c2cc1O InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2 QBUVZVXIRYFENV-UHFFFAOYSA-N 50004918 (+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride::CHEMBL288090::CHEMBL552611::SKF 77434 D(2) dopamine receptor Homo sapiens 580 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1241 103918465 63988 CHEMBL552611CHEMBL288090 ZINC03870332 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177515 Oc1cc2[C@H](C[NH2+]CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2/p+1/t13-/m1/s1 GHWJEDJMOVUXEC-CYBMUJFWSA-O 50067726 (R)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(6-Cl-PB)::SKF 81297 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332751 103962153 ZINC03783980 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177516 Oc1cc2C(CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2 HJWHHQIVUHOBQN-UHFFFAOYSA-N 50004917 3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide(Cl-APB)::CHEMBL35354::CHEMBL544115::RS(+/-)-6-Cl-APB3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SKF 82958 D(2) dopamine receptor Homo sapiens 136 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1225 103918464 CHEMBL35354CHEMBL544115 ZINC03870318 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177517 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177518 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 4.2 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177519 NC1CC1c1ccccc1 InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2 AELCINSCMGFISI-UHFFFAOYSA-N 50113851 (+/-)-Tranylcypromine::2-PCPA::2-Phenyl-cyclopropylamine::2-phenylcyclopropanamine::CHEMBL313833::TRANYLCYPROMINE::Tranylcypromine,(+)::Tranylcypromine,(-)::US8609708, 6 Tranyl- cypromine::US8609708, 6 Tranylcypromine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GJZ 3MDR 5530 104008102 CHEMBL313833 ZINC01639567 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177520 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Homo sapiens 0.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177521 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 50013515 (+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester D(2) dopamine receptor Homo sapiens 280 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8969 103925641 48565 CHEMBL15245 DB01392 102 C09256 ZINC03860825 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 177522 CN(C)C\C=C(\c1ccc(Br)cc1)c1cccnc1 InChI=1S/C16H17BrN2/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13/h3-10,12H,11H2,1-2H3/b16-9- OYPPVKRFBIWMSX-SXGWCWSVSA-N 50020706 CHEMBL37744::ZIMELIDINE::Zimeldine::[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine::[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine (Zimelidine)::[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine(Zimeldine)::cis -[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine;HCl::trans-[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine;C2H4O4 D(2) dopamine receptor Homo sapiens 1874 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020706&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5365247 103931465 CHEMBL37744 ZINC08099545 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173792 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Homo sapiens 89 PDSP Ki 10.7270/Q2CJ8C04 9067310 Lejeune, F; Newman-Tancredi, A; Audinot, V; Millan, MJ Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173793 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Homo sapiens 1780 PDSP Ki 10.7270/Q2CJ8C04 9067310 Lejeune, F; Newman-Tancredi, A; Audinot, V; Millan, MJ Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173794 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Homo sapiens 1746 PDSP Ki 10.7270/Q2CJ8C04 9067310 Lejeune, F; Newman-Tancredi, A; Audinot, V; Millan, MJ Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173795 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Homo sapiens 1082 PDSP Ki 10.7270/Q2CJ8C04 9067310 Lejeune, F; Newman-Tancredi, A; Audinot, V; Millan, MJ Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173796 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2CJ8C04 9067310 Lejeune, F; Newman-Tancredi, A; Audinot, V; Millan, MJ Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173797 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.43 PDSP Ki 10.7270/Q2CJ8C04 9067310 Lejeune, F; Newman-Tancredi, A; Audinot, V; Millan, MJ Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173798 CC(C)(C)NCC(O)COc1cccc2CCCSc12 InChI=1S/C16H25NO2S/c1-16(2,3)17-10-13(18)11-19-14-8-4-6-12-7-5-9-20-15(12)14/h4,6,8,13,17-18H,5,7,9-11H2,1-3H3 HTWFXPCUFWKXOP-UHFFFAOYSA-N 50280934 1-tert-Butylamino-3-(thiochroman-8-yloxy)-propan-2-ol::1-tert-Butylamino-3-(thiochroman-8-yloxy)-propan-2-ol(TERtatolol)::CHEMBL434200::TERTATOLOL(-)::Tertatolol D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2CJ8C04 9067310 Lejeune, F; Newman-Tancredi, A; Audinot, V; Millan, MJ Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 36920 104122638 CHEMBL434200 571 ZINC05352943 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173038 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Homo sapiens 4.8 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173039 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.09 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173040 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 190 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173041 Fc1ccc(cc1)C(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1 InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35) QOYHHIBFXOOADH-UHFFFAOYSA-N 26948 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL46516::FLUSPIRILENE::NCGC00015424::cid_3396::med.21724, Compound Fluspirilene::spiropiperidine analogue, 1 D(2) dopamine receptor Homo sapiens 0.67 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3396 57298659 CHEMBL46516 DB04842 85 ZINC00537755 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173042 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.2 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173043 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 31 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173044 CN1CC2C(C1)c1cc(Cl)ccc1Oc1ccccc21 InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3 VSWBSWWIRNCQIJ-UHFFFAOYSA-N 84994 CAS_163091::NSC_163091::ORG-5222 D(2) dopamine receptor Homo sapiens 1.87 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903970 136351094 71255 DB06216 ZINC11677376 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173045 NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1 InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27) AXKPFOAXAHJUAG-UHFFFAOYSA-N 81483 CAS_1893-33-0::NSC_4830::PIPAMPERONE D(2) dopamine receptor Homo sapiens 120 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4830 131342057 DB09286 92 ZINC21297287 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173046 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 700 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173047 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 5.9 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173048 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 7 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173049 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 4.6 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173050 CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3 HDOZVRUNCMBHFH-UHFFFAOYSA-N 35255 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine D(2) dopamine receptor Homo sapiens 11 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ZOT 6A94 5736 85753334 32316 CHEMBL285802 DB09225 103 ZINC00002264 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173051 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Homo sapiens 4.1 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173052 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.09 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173053 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 150 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173054 Fc1ccc(cc1)C(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1 InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35) QOYHHIBFXOOADH-UHFFFAOYSA-N 26948 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL46516::FLUSPIRILENE::NCGC00015424::cid_3396::med.21724, Compound Fluspirilene::spiropiperidine analogue, 1 D(2) dopamine receptor Homo sapiens 1.2 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3396 57298659 CHEMBL46516 DB04842 85 ZINC00537755 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173055 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.8 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173056 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 21 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173057 CN1CC2C(C1)c1cc(Cl)ccc1Oc1ccccc21 InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3 VSWBSWWIRNCQIJ-UHFFFAOYSA-N 84994 CAS_163091::NSC_163091::ORG-5222 D(2) dopamine receptor Homo sapiens 2.6 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903970 136351094 71255 DB06216 ZINC11677376 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173058 NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1 InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27) AXKPFOAXAHJUAG-UHFFFAOYSA-N 81483 CAS_1893-33-0::NSC_4830::PIPAMPERONE D(2) dopamine receptor Homo sapiens 110 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4830 131342057 DB09286 92 ZINC21297287 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173059 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 390 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173060 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 6.2 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173061 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 5.8 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173062 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 4.2 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 173063 CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3 HDOZVRUNCMBHFH-UHFFFAOYSA-N 35255 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine D(2) dopamine receptor Homo sapiens 5.4 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ZOT 6A94 5736 85753334 32316 CHEMBL285802 DB09225 103 ZINC00002264 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175580 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 60 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175581 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 190 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175582 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.67 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175583 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.2 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175584 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 31 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175585 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 700 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175586 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Homo sapiens 125 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175587 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 1.7 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175588 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 5.9 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175589 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 0.62 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175590 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 7 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175591 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 4.6 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175592 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 60 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175593 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.67 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175594 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Homo sapiens 125 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175595 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 1.7 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175596 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 0.62 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 175744 Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2[C@@]3(C)CCC(C3)C2(C)C)cc1 InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22?,27?,29-/m0/s1 SUGVYNSRNKFXQM-ACSDJOOWSA-N 21280 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl]-1H-pyrazole-3-carboxamide::N-(1,3,3-trimethylbicyclo(2.2.1)heptan-2-yl)-5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)pyrazole-3-carboxamide::SR 144528::SR-144528::SR144528 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2D50KHT 9454810 Rinaldi-Carmona, M; Barth, F; Millan, J; Derocq, JM; Casellas, P; Congy, C; Oustric, D; Sarran, M; Bouaboula, M; Calandra, B; Portier, M; Shire, D; Breliere, JC; Le Fur, GL Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21310426 49689352 ZINC03952700 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182164 COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12 InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23) ZPMNHBXQOOVQJL-UHFFFAOYSA-N 50122872 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide::CHEMBL117287::PRUCALOPRIDE::US9663465, prucalopride D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/s0014-2999(01)01087-1 10.7270/Q23T9FSX 11438309 Briejer, MR; Bosmans, JP; Van Daele, P; Jurzak, M; Heylen, L; Leysen, JE; Prins, NH; Schuurkes, JA Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3052762 104015490 CHEMBL117287 DB06480 243 ZINC01891034 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182277 CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1 InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 WSEQXVZVJXJVFP-UHFFFAOYSA-N 25870 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile::CHEMBL549::CITALOPRAM::CITALOPRAM HYDROBROMIDE::Escitalopram::[3H]Citalopram::[3H]Cytalopram::[3H]Escitalopram::[3H]Lexapro D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2QJ7FVW 11454918 Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68P 5I73,5I71,5I75 2771 56413158 3723 CHEMBL549 DB00215 4621 C07572 ZINC03800706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182278 CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12 InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 GDLIGKIOYRNHDA-UHFFFAOYSA-N 77970 3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-1-propanamine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-dimethyl-amine;hydrochloride::CHLORIMIPRAMINE::CLOMIPRAMINE::CLOMIPRAMINE HYDROCHLORIDE::CLOMIPRIMINE::MLS000028511::SMR000058295::cid_68539::med.21724, Compound Clomipramine D(2) dopamine receptor Homo sapiens 77.6 PDSP Ki 10.7270/Q2QJ7FVW 11454918 Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search CXX 4MMA,2QEI,6G9I,2Q6H 2801 252654733 3755 DB01242 C06918 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182279 CCOc1ccccc1O[C@H]([C@@H]1CNCCO1)c1ccccc1 InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19-/m0/s1 CBQGYUDMJHNJBX-OALUTQOASA-N 35226 (S,S)-reboxetine::Reboxetine::Vestra D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2QJ7FVW 11454918 Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35226&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65856 85753305 DB00234 4808 ZINC00006923 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182280 COc1ccc2CC(CN(C)C)(c2c1)C1(O)CCCCC1 InChI=1S/C18H27NO2/c1-19(2)13-17(18(20)9-5-4-6-10-18)12-14-7-8-15(21-3)11-16(14)17/h7-8,11,20H,4-6,9-10,12-13H2,1-3H3 UBIQMAFTTDZGEX-UHFFFAOYSA-N 85805 S33005 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2QJ7FVW 11454918 Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9925999 136351905 ZINC13914237 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182281 COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3 PNVNVHUZROJLTJ-UHFFFAOYSA-N 82071 CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.7270/Q2QJ7FVW 11454918 Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search VFX 8F4W 5656 131342645 DB00285 C07187 ZINC00896698 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180049 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Homo sapiens 158.48 PDSP Ki 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X 10.7270/Q2XK8D4N 10611634 Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180050 Fc1cccc2OC3CNCC3Oc12 InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2 XSOUHEXVEOQRKJ-UHFFFAOYSA-N 85595 CAS_105182-45-4::Fluparoxan::NSC_72036 D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X 10.7270/Q2XK8D4N 10611634 Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10219795 136351695 41 ZINC11680328 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180053 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 50013515 (+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester D(2) dopamine receptor Homo sapiens 398.1 PDSP Ki 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X 10.7270/Q2XK8D4N 10611634 Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8969 103925641 48565 CHEMBL15245 DB01392 102 C09256 ZINC03860825 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180439 CC1CCN(CC[C@H]2CCCN2[S](=O)(=O)c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C18H26Cl2N2O2S/c1-14-6-10-21(11-7-14)12-8-15-3-2-9-22(15)25(23,24)16-4-5-17(19)18(20)13-16/h4-5,13-15H,2-3,6-12H2,1H3/t15-/m1/s1 OQCUZRRTKCFWET-OAHLLOKOSA-N 85608 (R)-1-(2-(1-(3,4-Dichloro-benzene sulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1021/jm991151j 10.7270/Q28S4NGP 10669560 Lovell, PJ; Bromidge, SM; Dabbs, S; Duckworth, DM; Forbes, IT; Jennings, AJ; King, FD; Middlemiss, DN; Rahman, SK; Saunders, DV; Collin, LL; Hagan, JJ; Riley, GJ; Thomas, DR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85608&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10835110 136351708 ZINC13531261 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180440 CC1CCN(CC[C@H]2CCCN2[S](=O)(=O)c2cccc(Br)c2)CC1 InChI=1S/C18H27BrN2O2S/c1-15-7-11-20(12-8-15)13-9-17-5-3-10-21(17)24(22,23)18-6-2-4-16(19)14-18/h2,4,6,14-15,17H,3,5,7-13H2,1H3/t17-/m1/s1 JBIWUVRCMUOUNK-QGZVFWFLSA-N 85610 (R)-1-(2-(1-(3-bromo-benzenesulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine D(2) dopamine receptor Homo sapiens 794.33 PDSP Ki 10.1021/jm991151j 10.7270/Q28S4NGP 10669560 Lovell, PJ; Bromidge, SM; Dabbs, S; Duckworth, DM; Forbes, IT; Jennings, AJ; King, FD; Middlemiss, DN; Rahman, SK; Saunders, DV; Collin, LL; Hagan, JJ; Riley, GJ; Thomas, DR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85610&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10573876 136351710 ZINC13531264 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180441 CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc3ccccc23)CC1 InChI=1S/C22H30N2O2S/c1-18-11-15-23(16-12-18)17-13-20-8-5-14-24(20)27(25,26)22-10-4-7-19-6-2-3-9-21(19)22/h2-4,6-7,9-10,18,20H,5,8,11-17H2,1H3/t20-/m1/s1 VCFMMDVFGUQTHR-HXUWFJFHSA-N 50130278 (R)-4-Methyl-1-(2-(1-(naphthalene-1-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine(10)::(R)-4-Methyl-1-{2-[1-(naphthalene-1-sulfonyl)-pyrrolidin-2-yl]-ethyl}-piperidine::4-Methyl-1-{2-[(R)-1-(naphthalene-1-sulfonyl)-pyrrolidin-2-yl]-ethyl}-piperidine::CHEMBL94984 D(2) dopamine receptor Homo sapiens 630.96 PDSP Ki 10.1021/jm991151j 10.7270/Q28S4NGP 10669560 Lovell, PJ; Bromidge, SM; Dabbs, S; Duckworth, DM; Forbes, IT; Jennings, AJ; King, FD; Middlemiss, DN; Rahman, SK; Saunders, DV; Collin, LL; Hagan, JJ; Riley, GJ; Thomas, DR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10249573 104021712 CHEMBL94984 ZINC13531258 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180442 CC1CCN(CC[C@H]2CCCCC2[S](=O)(=O)c2cccc3ccccc23)CC1 InChI=1S/C24H33NO2S/c1-19-13-16-25(17-14-19)18-15-21-8-3-5-11-23(21)28(26,27)24-12-6-9-20-7-2-4-10-22(20)24/h2,4,6-7,9-10,12,19,21,23H,3,5,8,11,13-18H2,1H3/t21-,23?/m1/s1 MCIRPRZMCKIHBN-FKHAVUOCSA-N 85612 (R)-4-Methyl-1-(2-(1-(naphthalene-1-sulfonyl)-piperidin-2-yl)-ethyl)-piperidine(5) D(2) dopamine receptor Homo sapiens 398.11 PDSP Ki 10.1021/jm991151j 10.7270/Q28S4NGP 10669560 Lovell, PJ; Bromidge, SM; Dabbs, S; Duckworth, DM; Forbes, IT; Jennings, AJ; King, FD; Middlemiss, DN; Rahman, SK; Saunders, DV; Collin, LL; Hagan, JJ; Riley, GJ; Thomas, DR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85612&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340195 136351712 ZINC87722958 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181622 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Homo sapiens 2.8 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181623 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 210 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181624 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.6 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181625 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 XMXHEBAFVSFQEX-UHFFFAOYSA-N 50034043 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE D(2) dopamine receptor Homo sapiens 3.3 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71360 103942259 65173 CHEMBL14376 DB04946 87 ZINC01548097 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181626 CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 DKMFBWQBDIGMHM-UHFFFAOYSA-N 81771 CAS_3575-80-2::MELPERONE::NSC_15387 D(2) dopamine receptor Homo sapiens 180 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15387 131342345 DB09224 ZINC00001672 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181627 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 20 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181628 CN1CC2C(C1)c1cc(Cl)ccc1Oc1ccccc21 InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3 VSWBSWWIRNCQIJ-UHFFFAOYSA-N 84994 CAS_163091::NSC_163091::ORG-5222 D(2) dopamine receptor Homo sapiens 2 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903970 136351094 71255 DB06216 ZINC11677376 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181629 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 29 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181630 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 770 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181631 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 3.77 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181632 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 2.7 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181633 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.28 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181634 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 2.6 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180443 CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(C)c2)CC1 InChI=1S/C19H30N2O2S/c1-16-8-12-20(13-9-16)14-10-18-6-4-11-21(18)24(22,23)19-7-3-5-17(2)15-19/h3,5,7,15-16,18H,4,6,8-14H2,1-2H3/t18-/m1/s1 YVWGGGGMRDLOGA-GOSISDBHSA-N 50130279 (R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine (Oxalate salt)::4-Methyl-1-{2-[(R)-1-(toluene-3-sulfonyl)-pyrrolidin-2-yl]-ethyl}-piperidine::4-Methyl-1-{2-[(S)-1-(toluene-3-sulfonyl)-pyrrolidin-2-yl]-ethyl}-piperidine::4-Methyl-1-{2-[1-(toluene-3-sulfonyl)-pyrrolidin-2-yl]-ethyl}-piperidine::CHEMBL12624::SB-258741 D(2) dopamine receptor Homo sapiens 1584.89 PDSP Ki 10.1021/jm991151j 10.7270/Q28S4NGP 10669560 Lovell, PJ; Bromidge, SM; Dabbs, S; Duckworth, DM; Forbes, IT; Jennings, AJ; King, FD; Middlemiss, DN; Rahman, SK; Saunders, DV; Collin, LL; Hagan, JJ; Riley, GJ; Thomas, DR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9863250 104021713 CHEMBL12624 ZINC04393149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180444 CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1 HWKROQUZSKPIKQ-MRXNPFEDSA-N 50098551 (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol::(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol::3-{(R)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol::3-{(S)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol::3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol::3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol (SB-269970)::CHEMBL282199::SB-269970 D(2) dopamine receptor Homo sapiens 316.23 PDSP Ki 10.1021/jm991151j 10.7270/Q28S4NGP 10669560 Lovell, PJ; Bromidge, SM; Dabbs, S; Duckworth, DM; Forbes, IT; Jennings, AJ; King, FD; Middlemiss, DN; Rahman, SK; Saunders, DV; Collin, LL; Hagan, JJ; Riley, GJ; Thomas, DR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604889 103995564 CHEMBL282199 3233 ZINC03982174 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 181635 CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3 HDOZVRUNCMBHFH-UHFFFAOYSA-N 35255 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine D(2) dopamine receptor Homo sapiens 8 PDSP Ki 10.1016/s0024-3205(00)00911-5 10.7270/Q2057DHP 11132243 Richelson, E; Souder, T Mayo Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ZOT 6A94 5736 85753334 32316 CHEMBL285802 DB09225 103 ZINC00002264 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180870 CCCN(CCC)C1CCc2cc(CS(=O)(=O)c3ccc(OC)cc3)ccc2C1 InChI=1S/C24H33NO3S/c1-4-14-25(15-5-2)22-9-8-20-16-19(6-7-21(20)17-22)18-29(26,27)24-12-10-23(28-3)11-13-24/h6-7,10-13,16,22H,4-5,8-9,14-15,17-18H2,1-3H3 HUXFXXWYIRBVJR-UHFFFAOYSA-N 50240797 6-((4-methoxyphenylsulfonyl)methyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine::CHEMBL334529::GR-218231::GR218231::[6-(4-Methoxy-benzenesulfonylmethyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dipropyl-amine D(2) dopamine receptor Homo sapiens 63.10 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24840389 104098462 CHEMBL334529 ZINC06013412 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182026 C(N1CCN(CC1)c1ncccn1)c1ccc2OCOc2c1 InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2 OQDPVLVUJFGPGQ-UHFFFAOYSA-N 85092 CAS_3605-01-4::NSC_4850::Piribedil D(2) dopamine receptor Homo sapiens 131.83 PDSP Ki 10.7270/Q2W957RF 11356907 Millan, MJ; Cussac, D; Milligan, G; Carr, C; Audinot, V; Gobert, A; Lejeune, F; Rivet, JM; Brocco, M; Duqueyroix, D; Nicolas, JP; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4850 136351192 ZINC19537374 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 178364 CCCCCCOc1nsnc1C1=CCCN(C)C1 InChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3 JOLJIIDDOBNFHW-UHFFFAOYSA-N 50003359 5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine; oxalic acid::5-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1-methyl-1,2,3,6-tetrahydropyridine::CHEMBL21536::CHEMBL73149::LY 246708::Xanomeline D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1038/sj.bjp.0702201 10.7270/Q2HM56ZD 9884068 Watson, J; Brough, S; Coldwell, MC; Gager, T; Ho, M; Hunter, AJ; Jerman, J; Middlemiss, DN; Riley, GJ; Brown, AM SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003359&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60809 103917332 10056 CHEMBL21536CHEMBL73149 57 C11767 ZINC01532358 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180872 CCCN(CCC)C1CCc2cc(CS(=O)(=O)c3ccc(OC)cc3)ccc2C1 InChI=1S/C24H33NO3S/c1-4-14-25(15-5-2)22-9-8-20-16-19(6-7-21(20)17-22)18-29(26,27)24-12-10-23(28-3)11-13-24/h6-7,10-13,16,22H,4-5,8-9,14-15,17-18H2,1-3H3 HUXFXXWYIRBVJR-UHFFFAOYSA-N 50240797 6-((4-methoxyphenylsulfonyl)methyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine::CHEMBL334529::GR-218231::GR218231::[6-(4-Methoxy-benzenesulfonylmethyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dipropyl-amine D(2) dopamine receptor Homo sapiens 138.04 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24840389 104098462 CHEMBL334529 ZINC06013412 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180873 OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 InChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 LLBLNMUONVVVPG-UHFFFAOYSA-N 50050467 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol::3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole::4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol::CHEMBL445102::L-741626::L741,626 D(2) dopamine receptor Homo sapiens 3.98 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133633 103947637 CHEMBL445102 177 ZINC00006788 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180875 OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 InChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 LLBLNMUONVVVPG-UHFFFAOYSA-N 50050467 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol::3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole::4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol::CHEMBL445102::L-741626::L741,626 D(2) dopamine receptor Homo sapiens 6.61 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133633 103947637 CHEMBL445102 177 ZINC00006788 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180876 O=C(NCCCCN1C[C@@H]2COc3ccc(cc3[C@H]2C1)C#N)c1ccc(cc1)-c1ccccc1 InChI=1S/C29H29N3O2/c30-17-21-8-13-28-26(16-21)27-19-32(18-25(27)20-34-28)15-5-4-14-31-29(33)24-11-9-23(10-12-24)22-6-2-1-3-7-22/h1-3,6-13,16,25,27H,4-5,14-15,18-20H2,(H,31,33)/t25-,27+/m1/s1 QQJHRQZZCNYDMX-VPUSJEBWSA-N 85672 S33084 D(2) dopamine receptor Homo sapiens 31.62 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9868452 136351772 ZINC03941217 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180878 O=C(NCCCCN1C[C@@H]2COc3ccc(cc3[C@H]2C1)C#N)c1ccc(cc1)-c1ccccc1 InChI=1S/C29H29N3O2/c30-17-21-8-13-28-26(16-21)27-19-32(18-25(27)20-34-28)15-5-4-14-31-29(33)24-11-9-23(10-12-24)22-6-2-1-3-7-22/h1-3,6-13,16,25,27H,4-5,14-15,18-20H2,(H,31,33)/t25-,27+/m1/s1 QQJHRQZZCNYDMX-VPUSJEBWSA-N 85672 S33084 D(2) dopamine receptor Homo sapiens 52.48 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9868452 136351772 ZINC03941217 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 180941 O=C(NC1CC[C@H](CCN2CCc3cc(ccc3C2)C#N)CC1)c1ccnc2ccccc12 InChI=1S/C28H30N4O/c29-18-21-5-8-23-19-32(16-13-22(23)17-21)15-12-20-6-9-24(10-7-20)31-28(33)26-11-14-30-27-4-2-1-3-25(26)27/h1-5,8,11,14,17,20,24H,6-7,9-10,12-13,15-16,19H2,(H,31,33)/t20-,24? OLWRVVHPJFLNPW-WVZUTIKQSA-N 50167898 CHEMBL85606::N-((1r,4r)-4-(2-(6-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)quinoline-4-carboxamide::N-(-4-(2-(6-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)quinoline-4-carboxamide::Quinoline-4-carboxylic acid {4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-amide::SB-277011::SB-277011-A::trans-N-[4-[2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2yl)-ethyl]cyclo-hexyl]-4-quinolinecarboxamide::trans-N-[4-[2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2yl)ethyl]-cyclohexyl]-4-quinolininecarboxamide D(2) dopamine receptor Homo sapiens 1047.12 PDSP Ki 10.7270/Q2K35S7G 10945872 Reavill, C; Taylor, SG; Wood, MD; Ashmeade, T; Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Cilia, J; Coldwell, MC; Hadley, MS; Hunter, AJ; Jeffrey, P; Jewitt, F; Johnson, CN; Jones, DN; Medhurst, AD; Middlemiss, DN; Nash, DJ; Riley, GJ; Routledge, C; Stemp, G; Thewlis, KM; Trail, B; Vong, AK; Hagan, JJ SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167898&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311096 104053095 CHEMBL85606 143 ZINC26574567 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184732 CNCCC(Oc1ccccc1C)c1ccccc1 InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3 VHGCDTVCOLNTBX-UHFFFAOYSA-N 50022784 (R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine::ATOMOXETINE::CHEMBL641::Methyl-((R)-3-phenyl-3-o-tolyloxy-propyl)-amine::Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine::Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine(tomoxetine)::Strattera::Tomoxetine D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1016/S0893-133X(02)00346-9 10.7270/Q2GQ6W98 12431845 Bymaster, FP; Katner, JS; Nelson, DL; Hemrick-Luecke, SK; Threlkeld, PG; Heiligenstein, JH; Morin, SM; Gehlert, DR; Perry, KW Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6850813 103933341 CHEMBL641 ZINC02570822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185972 NC(CSSCC(N)C(O)=O)C(O)=O InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12) LEVWYRKDKASIDU-UHFFFAOYSA-N 86199 CAS_595::CAS_67678::D-cystine::L-cystine::NSC_595::NSC_67678 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search IYY 8DKM,7ZKW 595 136352299 17376 C01420 ZINC01532673 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185973 N[C@H](CCS(O)(=O)=O)C(O)=O InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m1/s1 VBOQYPQEPHKASR-GSVOUGTGSA-N 86196 D-homocysteic acid D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86196&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 185861 136352296 C15521 ZINC02545126 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185974 N[C@H](CCS(O)=O)C(O)=O InChI=1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m1/s1 PDNJLMZEGXHSCU-GSVOUGTGSA-N 86197 D-homocysteine sulfinic acid D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23844143 136352297 C01615 ZINC25720437 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185975 N[C@@H]1CCSC1=O InChI=1S/C4H7NOS/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m1/s1 KIWQWJKWBHZMDT-GSVOUGTGSA-N 86205 D-homocysteine thiolactone D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86205&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7057932 136352305 ZINC54009854 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185976 CSCCC(N)C(O)=O InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8) FFEARJCKVFRZRR-UHFFFAOYSA-N 86195 CAS_6137::CAS_84815::D-methionine::L-methionine::NSC_6137::NSC_84815 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search MED 4GLS,4GLU,1Y9Q,1ZUE,5CGO,5CGN,1TKJ,6CNU,3TRY,7P5R,6DZX,3GP4,3TRV,8F16,6WI3,6JV7,4OIJ,4OIK,6PHQ,6PHN,6PHM,1KQ0,5I5A,5I5B,6WKB,2Q33,7UO8,5HHD,5XPK,3TJW,5I1P,5I1S,5I1O,5I1N 876 136352295 16811 C01733 ZINC01532766 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185977 NC(CCS(O)(=O)=O)C(O)=O InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10) VBOQYPQEPHKASR-UHFFFAOYSA-N 50164447 2-amino-4-sulfobutanoic acid::CHEMBL191727::DL-homocysteic acid D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search HJT 6Q6J 92117 104050228 CHEMBL191727 C15521 ZINC02567965 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185978 NC(CCS)C(O)=O InChI=1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7) FFFHZYDWPBMWHY-UHFFFAOYSA-N 86202 CAS_778::DL-homocysteine::NSC_778 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86202&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search HCS 4YGW,3BOF,4HPD,2N0I,3BQ5,1Q8J,2LP2,4M3P,4L6H,2CI5,1U22,3BOL,3VK4,5OTT,5OTU,5OTV,5OTW,4L5Z,1JVI,6IQG,6R28,5F2Y,5WT5,4XFI,4XFA,4XF9,4XF4,1JQW,1XDJ,8BIX,4QQU,5X30,4PIZ,4PIY,5DMM,1Q8A,6VJU,6PO4,7F1V 778 136352302 17230 C05330 ZINC00895703 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185979 NC(CS(O)(=O)=O)C(O)=O InChI=1S/C3H7NO5S/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9) XVOYSCVBGLVSOL-UHFFFAOYSA-N 85473 L-Cysteic acid, 8::L-cysteic acid D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 00C 3FII 25701 136351573 21260 C15521 ZINC04228276 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185980 NC(CS)C(O)=O InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6) XUJNEKJLAYXESH-UHFFFAOYSA-N 86203 CAS_5862::L-cysteine::NSC_5862 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86203&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search BTC 1B23,1D7P,1ECX,1GKM,1GL3,1HFE,1I1A,1LI7,1MB4,1N26,1N31,1O7S,1PQU,1R4S,1R51,1RZG,1SSQ,1T3D,1V1Q,1XT8,208L,2D32,2D33,2DF3,2FUB,2G5R,2IBN,2IC1,2ICQ,2IO8,2IX7,2PAD,2V43,2WB9,2YJP,2YLN,2ZSV,3A9Y,3BM5,3C01,3ENJ,3GVD,3P47,3PZR,3Q0E,3TZ6,3V6O,4BB2,4BFE,4BFG,4BFI,4FF9,4G1P,4H7O,4HPC,4IEV,4IEW,4JH8,4JTO,4KSZ,4LMB,4NB0,4NB1,4OTZ,4OWD,4QM8,4QM9,4XF0,4XF1,4XF3,4XFG,4XFH,4YTG,4Z82,4ZU9,5B36,5DB5,5EH1,5EIG,5HCC,5HCD,5HCE,7API,8API,9API 594 136352303 15356 C00736 ZINC00895347 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185981 NC(CS(O)=O)C(O)=O InChI=1S/C3H7NO4S/c4-2(3(5)6)1-9(7)8/h2H,1,4H2,(H,5,6)(H,7,8) ADVPTQAUNPRNPO-UHFFFAOYSA-N 86194 CAS_109::L-cysteine sulfinic acid::NSC_109 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86194&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search CSD 1EU1,6IKY,6IKT,6Z9O,5NY7,3E9Y,3H4H,6W0U,1TO9,3PHU,3VYH,3VYG,6MTG,4U8E,4Y1R,4Y1F,4G6W,5Z3D,5F8E,5F8F,5F8C,3PSZ,4QYT,1REV,1JKH,3TKK,3TKS,6Z9G,1BQ6,4AGI,6WE7,4NYO,4NYP,3WVD,3WVE,6R6U,4Z37,3FIV,3A8M,7L1P,1XW4,6PT4,3HHT,6Z8M,1FNK,6RUC,1VRU,1Z8N,7LR3,1BI5,4OMR,3H56,3QZ5,3QZ9,2QUG,6FTQ,7Z0V,2Z1D,6DXB,6DXC,6DXA,6DXD,6DX9,7PI0,6MU0,3U7M,3U7L,3U7N,3U7K,5WC4,5B6N,6B4R,1VI9,2ZPB,2ZPG,5K6R,5K6Q,5K6T,5IPG,5FZO,3QOR,7W6G,1SUC,1SUB,1SUD,1Q9U,4AY8,4AY7,7QOY,7QOU,7QOP,7QOM,2FHX,6RTP,3PG8,3QYG,3QYH,4PSS,4PST,4PSY,1TKT,2OPQ,2OPP,2OPS,2OPR,2OPL,2ZZD,7PJN,3I1H,3KI8,1WUO,4OQ4,8ET5,8ET4,2PVZ,1OBF,5V2W,5UR0,4CHL,2C47,5JSH,5JSU,3SMH,2J16,5IMF,5GK0,6RIZ,2R3Q,2R3P,2R3I,2R3K,2R3J,2R3M,2R3L,2R3O,2R3N,5INY,1LW2,1LW0,1LWC,1LWF,1LWE,4IEF,6ISQ,6G4R,5NAI,6N1A,2X1E,3HJ0,4NT8,3WEU,4R0V,4RYB,3QXE,1U9C,4ZGJ,4ZGE,4ZGD,1EKQ,1EKK,1MHW,3X26,3X25,3X24,3X20,3X28,7F87,7F8S,2HL8,3AWJ,3DLE,3DLG,1Q79,1Q78,3C5Y,3A8H,3OQP,3OQI,1DNC,1TKZ,5FQA,2BGA,2BG6,5JT1,1UGR,3SLE,4YUF,2ZCF,5VEX,5VEW,6G5M,5HWR,7AYJ,2IMZ,7U1D,7U1U,4P2G,4EKF,6ZK6,3T8E,4YKG,5NUE,5JQN,3ZJG,3ZJF,2V9S,1OBB,8ADD,6W42,1OKI,7XCF,7W8L,7W8M,4KPH,4U2C,3R66,1JLQ,1JLC,1JLB,1JLE,1JLG,4G2O,7BUR,7BUS,2ETF,7FFA,3P5U,1TL3,1TL1,5IMD,5IMZ,2BFZ,2GCU,6H2U,3L87,6TYY,3BC2,3BC3,3GEF,5SYA,5VF5,2ACT,1DIN,6BKA,1YBH,4LDK,2VYN,2VYV,1YM9,2DD5,1YSL,4OB1,4OB0,4OB3,4OB2,7CTM,1TVZ,1EP4,1UKK,7ZM9,5CPD,1RTH,1RTJ,1RT1,1RT3,1RT2,1RT5,1RT4,1RT7,1RT6,3T6S,1EE0,7STQ,3DMJ,6FXS,1JLA,1JLF,7TZZ,2HNY,2HNZ,2HND,1IRE,3SED,4GE3,5Z89,3EU7,3EUO,3EUT,3EUQ,3MI2,7ARF,3AWK,2E2M,4XLL,1YI1,1YI0,6YG4,4QIB,1TXT,3A9C,2QDY,2D5H,2D51,2D52,2RK6,4WPZ,1V5I,3NRA,7PNK,1VJE,2DPP,7JH0,3UK7,3CWM,3CWL,6UTN,2VB7,5IZD,3DOL,3DOK,2WLX,2WLR,2WL4,4AH4,1I86,3DM2,5IO0,1S1W,1S1V,1S1U,1S1T,1S1X,6VX2,6GW3,3SQZ,5SY9,5WSE,5WSD,5WSF,5H5S,7B1Y,7B1V,4GE0,4WZ0,2OJP,4M5P,5LRY,5LRX,1YHY,4QJE,3A8G,3A8L,3A8O,2D0Q,4WQ8,4WQ9,5G5H,2P0U,7B23,1R7A,1D6I,1D6H,3EA4,5UC5,7QOV,5K2O,5K3S,3H8C,5J78,2X1D,5W3V,1OEU,3SGU,2H9W,6L2D,6L2E,6L2F,5IOW,2C9H,1I88,1I89,5W8Q,6Z7R,3TB2,3LQY,2GDU,7NAY,1SOA,6IL2,6IL0,2RIL,2D3M,3IW3,7A74,7LVC,7UNZ,1W8C,4UAM,3UIO,3UIP,5C7I,4BPY,3CYF,5V5H,1Q1Y,5G5G,1DTT,1DTQ,1VGX,2CYZ,7FBQ,3IL9,4U85,2OAN,1YHZ,1I8B,2AHJ,6Z8J,1ACD,1TKX,1QMV,7T8L,5Y0S,5Y0T,1JWX,4GD7,7KJ0,1FK9,1FKP,1FKO,2G82,6I7R,6I7Q,4FLM,1QFM,2DXB,2DXC,4PIO,1UGP,1OCH,4P5P,4TTG,4RGC,2EG3,2HAI,4PTH,4PTJ,3F5V,2CZ0,2CZ7,2CZ6,4NJ3,1KLM,3EZG,1C1C,1C1B,4V2P,3OP0,4N12,6K5J,2ZPH,2ZPI,2ZPE,2ZPF,6XKH,1QLV,2NQT,1GZ8,6YCB,2D5F,1RTI,2CZ1,7C9J,4I07,4IW7,6ZA1,6C9U,5E68,4ORN,4D52,4Y0N,6B6L,2BC0,2BC2,7MKV,1C0T,1C0U,6ED0,6JFO,1VRT,6QUN,4FM4,6ESZ 109 136352294 4695 C01615 ZINC12501661 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185982 NC(CSSCC(N)C(O)=O)C(O)=O InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12) LEVWYRKDKASIDU-UHFFFAOYSA-N 86199 CAS_595::CAS_67678::D-cystine::L-cystine::NSC_595::NSC_67678 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search IYY 8DKM,7ZKW 595 136352299 17376 C01420 ZINC01532673 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185983 N[C@@H](CCS(O)(=O)=O)C(O)=O InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1 VBOQYPQEPHKASR-VKHMYHEASA-N 50220147 (S)-2-amino-4-sulfobutanoic acid::CHEMBL230951::L-2-amino-4-sulfobutyric acid::L-Homocysteate::L-homocysteic acid D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220147&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search HJT 6Q6J 177491 104093189 CHEMBL230951 C16511 ZINC02567965 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185984 N[C@@H](CCS(O)=O)C(O)=O InChI=1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1 PDNJLMZEGXHSCU-VKHMYHEASA-N 86201 L-homocysteine sulfinic acid D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86201&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 75896 136352301 C01615 ZINC12953438 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185985 N[C@H]1CCSC1=O InChI=1S/C4H7NOS/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m0/s1 KIWQWJKWBHZMDT-VKHMYHEASA-N 86198 CAS_134505::L-homocysteine thiolactone::NSC_134505 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86198&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134505 136352298 60315 ZINC54009855 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185986 CSCCC(N)C(O)=O InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8) FFEARJCKVFRZRR-UHFFFAOYSA-N 86195 CAS_6137::CAS_84815::D-methionine::L-methionine::NSC_6137::NSC_84815 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.102.047092 10.7270/Q2VT1QN7 12649361 Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search MED 4GLS,4GLU,1Y9Q,1ZUE,5CGO,5CGN,1TKJ,6CNU,3TRY,7P5R,6DZX,3GP4,3TRV,8F16,6WI3,6JV7,4OIJ,4OIK,6PHQ,6PHN,6PHM,1KQ0,5I5A,5I5B,6WKB,2Q33,7UO8,5HHD,5XPK,3TJW,5I1P,5I1S,5I1O,5I1N 876 136352295 16811 C01733 ZINC01532766 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184835 CC(CN(C)C)CN1c2ccccc2Sc2ccc(cc12)C#N InChI=1S/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15(11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3 SLFGIOIONGJGRT-UHFFFAOYSA-N 86057 CAS_62865::Cyamemazine::NSC_62865 D(2) dopamine receptor Homo sapiens 5.8 PDSP Ki 10.1016/s0006-2952(02)01515-0 10.7270/Q2Q81BMG 12527336 Hameg, A; Bayle, F; Nuss, P; Dupuis, P; Garay, RP; Dib, M Aventis Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86057&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 62865 136352157 DB09000 84 ZINC05320256 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187603 CC1N(C)C[C@H]2c3ccc(O)c(O)c3Cc3cccc1c23 InChI=1S/C18H19NO2/c1-10-12-5-3-4-11-8-14-13(6-7-16(20)18(14)21)15(17(11)12)9-19(10)2/h3-7,10,15,20-21H,8-9H2,1-2H3/t10?,15-/m0/s1 IOOBOXRVKPVBIV-WRXSAAJRSA-N 86467 (+/-)-2,3-Dimethyldinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340608 136352516 ZINC13479459 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187605 CCCN1C[C@H]2c3ccc(O)c(O)c3Cc3cccc(C1)c23 InChI=1S/C19H21NO2/c1-2-8-20-10-13-5-3-4-12-9-15-14(16(11-20)18(12)13)6-7-17(21)19(15)22/h3-7,16,21-22H,2,8-11H2,1H3/t16-/m0/s1 VKSXADRMMBMNET-INIZCTEOSA-N 86178 (+/-)-2-propyldinapsoline hydrobromide::Dinapsoline,(+/-)-N-propyl D(2) dopamine receptor Homo sapiens 15 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340487 136352278 ZINC13478198 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187606 CC1NC[C@H]2c3ccc(O)c(O)c3Cc3cccc1c23 InChI=1S/C17H17NO2/c1-9-11-4-2-3-10-7-13-12(5-6-15(19)17(13)20)14(8-18-9)16(10)11/h2-6,9,14,18-20H,7-8H2,1H3/t9?,14-/m0/s1 DTPSKKIRHCHXKH-RJSPSEDBSA-N 86462 (+/-)-3-methyldinapsoline hydrobromide D(2) dopamine receptor Homo sapiens 40 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340604 136352511 ZINC13479453 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187618 CCc1ccc2CNC[C@H]3c4ccc(O)c(O)c4Cc1c23 InChI=1S/C18H19NO2/c1-2-10-3-4-11-8-19-9-15-12-5-6-16(20)18(21)14(12)7-13(10)17(11)15/h3-6,15,19-21H,2,7-9H2,1H3/t15-/m0/s1 OEKDIZGIBLUFQR-HNNXBMFYSA-N 86454 6-ethyldinapsoline hydrobromide D(2) dopamine receptor Homo sapiens 27 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340596 136352503 ZINC13479469 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187619 Oc1ccc2C3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2 ZQTSNGJHMUKLOM-UHFFFAOYSA-N 50117182 2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL120995::Dinapsoline, (+/-) D(2) dopamine receptor Homo sapiens 10.7 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5249490 104010782 CHEMBL120995 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187621 Oc1ccc2[C@@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2/t13-/m0/s1 ZQTSNGJHMUKLOM-ZDUSSCGKSA-N 50117181 (S)-2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL124561::Dinapsoline, (+/-)::Dinapsoline, (R)(+) D(2) dopamine receptor Homo sapiens 11.1 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816455 104010781 CHEMBL124561 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182665 CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1 ZEUITGRIYCTCEM-KRWDZBQOSA-N 84745 CAS_136434-34-9::DULOXETINE::LY-248686::LY248686::USRE49340, Rank 5 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/S0893-133X(01)00298-6 10.7270/Q25M648W 11750180 Bymaster, FP; Dreshfield-Ahmad, LJ; Threlkeld, PG; Shaw, JL; Thompson, L; Nelson, DL; Hemrick-Luecke, SK; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84745&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 29E 4MMD,4MM6,6M38 60835 136350845 36808 DB00476 ZINC01536779 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182666 COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3 PNVNVHUZROJLTJ-UHFFFAOYSA-N 82071 CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1016/S0893-133X(01)00298-6 10.7270/Q25M648W 11750180 Bymaster, FP; Dreshfield-Ahmad, LJ; Threlkeld, PG; Shaw, JL; Thompson, L; Nelson, DL; Hemrick-Luecke, SK; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search VFX 8F4W 5656 131342645 DB00285 C07187 ZINC00896698 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184020 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 31.8 PDSP Ki 10.1016/s0014-2999(02)02074-5 10.7270/Q2S75DX4 12176106 Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184021 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 11.7 PDSP Ki 10.1016/s0014-2999(02)02074-5 10.7270/Q2S75DX4 12176106 Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184022 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1016/s0014-2999(02)02074-5 10.7270/Q2S75DX4 12176106 Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184023 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 2.7 PDSP Ki 10.1016/s0014-2999(02)02074-5 10.7270/Q2S75DX4 12176106 Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184024 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 6.55 PDSP Ki 10.1016/s0014-2999(02)02074-5 10.7270/Q2S75DX4 12176106 Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184025 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 26.7 PDSP Ki 10.1016/s0014-2999(02)02074-5 10.7270/Q2S75DX4 12176106 Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184026 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 8.5 PDSP Ki 10.1016/s0014-2999(02)02074-5 10.7270/Q2S75DX4 12176106 Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D Aventis Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 182759 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 XMXHEBAFVSFQEX-UHFFFAOYSA-N 50034043 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE D(2) dopamine receptor Homo sapiens 21.4 PDSP Ki 10.1016/S0893-133X(01)00285-8 10.7270/Q21V5CHQ 11750183 Kalkman, HO; Subramanian, N; Hoyer, D Novartis Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71360 103942259 65173 CHEMBL14376 DB04946 87 ZINC01548097 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 186543 CNC(C)Cc1ccc2OCOc2c1 InChI=1S/C11H15NO2/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10/h3-4,6,8,12H,5,7H2,1-2H3 SHXWCVYOXRDMCX-UHFFFAOYSA-N 50010588 (RS)-3,4-(methylenedioxy)methamphetamine::1-(1,3-Benzodioxol-5-yl)-N-methyl-2-propanamine::1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine::3,4-methylenedioxymethamphetamine::CHEMBL43048::DL-(3,4-Methylenedioxy)methamphetamine::MDMA::N,alpha-dimethyl-1,3-benzodioxole-5-ethanamine::N-Methyl-3,4-methylenedioxyamphetamine D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/mol.63.6.1223 10.7270/Q2FN14SJ 12761331 Setola, V; Hufeisen, SJ; Grande-Allen, KJ; Vesely, I; Glennon, RA; Blough, B; Rothman, RB; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010588&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search B41 3GM0 1615 103923364 1391 CHEMBL43048 DB01454 4574 C07577 ZINC00403053 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184105 COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1 InChI=1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1 OBSYBRPAKCASQB-AGQYDFLVSA-N 50159165 (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho-[2,1-c]pyran-7-carboxylic acid methyl ester::(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-(acetylthio)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro-1H-benzo[f]isochromene-7-carboxylate::(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro-1H-benzo[f]isochromene-7-carboxylate::(3S,4aR,4bS,6S,8R,8aR,10aR)-6-Acetoxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester::2S,4aR,6a(R,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester::CHEMBL445332::Salvinorin A::Salvonorin A::salvinorin-A D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1073/pnas.182234399 10.7270/Q2CZ35Q9 12192085 Roth, BL; Baner, K; Westkaemper, R; Siebert, D; Rice, KC; Steinberg, S; Ernsberger, P; Rothman, RB Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128563 104045748 67900 CHEMBL445332 1666 ZINC13607514 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185457 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 0.66 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185458 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 4 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185459 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 256 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185460 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Homo sapiens 0.54 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185461 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 4 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185462 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 12 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185463 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Homo sapiens 63 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185464 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 34 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185465 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 RGCVKNLCSQQDEP-UHFFFAOYSA-N 50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine D(2) dopamine receptor Homo sapiens 1.4 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4748 104021707 8028 CHEMBL567 DB00850 209 C07427 ZINC19228902 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185466 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 0.65 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185467 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 245 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185468 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 6.5 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185469 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 9.1 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185470 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 11 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185471 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3C(=CCCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3 GFBKORZTTCHDGY-UHFFFAOYSA-N 86187 CAS_22189-31-7::NSC_5454::THIOTHIXENE D(2) dopamine receptor Homo sapiens 0.63 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86187&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941650 136352287 ZINC29747244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185472 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Homo sapiens 1.3 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 185473 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 9.7 PDSP Ki 10.1038/sj.npp.1300027 10.7270/Q2833QKK 12629531 Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 186635 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 3.3 PDSP Ki 10.1038/sj.npp.1300203 10.7270/Q2639N9T 12784105 Shapiro, DA; Renock, S; Arrington, E; Chiodo, LA; Liu, LX; Sibley, DR; Roth, BL; Mailman, R Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 186636 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 0.74 PDSP Ki 10.1038/sj.npp.1300203 10.7270/Q2639N9T 12784105 Shapiro, DA; Renock, S; Arrington, E; Chiodo, LA; Liu, LX; Sibley, DR; Roth, BL; Mailman, R Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184614 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 83.18 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184615 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 14.79 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184616 CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(Cc3c[nH]c4cccc2c34)N(CC=C)C1 InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33) KORNTPPJEAJQIU-UHFFFAOYSA-N 86052 CAS_54746::Cabergoline::NSC_54746 D(2) dopamine receptor Homo sapiens 0.95 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2512 136352152 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184617 CCN(CC)C(=O)N[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18-/m1/s1 BKRGVLQUQGGVSM-RDTXWAMCSA-N 22867 1,1-diethyl-3-[(8beta)-6-methyl-9,10-didehydroergolin-8-yl]urea::3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),2,9,12(16),13-pentaen-4-yl]urea::8R-lisuride::LISURIDE D(2) dopamine receptor Homo sapiens 0.66 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11957615 49846681 ZINC03831002 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184618 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50028421 9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid::CHEMBL1275::LY-127809::PERGOLIDE MESYLATE::Pergolide::Permax D(2) dopamine receptor Homo sapiens 25.70 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103937709 8021 CHEMBL1275 DB01186 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 183419 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 1606 PDSP Ki 10.1124/jpet.301.3.1179 10.7270/Q2QF8RFK 12023553 Kilts, JD; Connery, HS; Arrington, EG; Lewis, MM; Lawler, CP; Oxford, GS; O'Malley, KL; Todd, RD; Blake, BL; Nichols, DE; Mailman, RB University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 183420 CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m1/s1 VNVHTKVGILYCGH-YLJYHZDGSA-N 50010684 (6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL299161::N-n-propyldihydrexidine, N-Pr-DHX D(2) dopamine receptor Homo sapiens 2108 PDSP Ki 10.1124/jpet.301.3.1179 10.7270/Q2QF8RFK 12023553 Kilts, JD; Connery, HS; Arrington, EG; Lewis, MM; Lawler, CP; Oxford, GS; O'Malley, KL; Todd, RD; Blake, BL; Nichols, DE; Mailman, RB University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9904738 103923430 CHEMBL299161 ZINC13478187 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 183421 OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22) JXTHEWSKYLZVJC-UHFFFAOYSA-N 81777 CAS_132-66-1::NPA::NPA,(+)::NPA,(-)::NSC_8594 D(2) dopamine receptor Homo sapiens 3243 PDSP Ki 10.1124/jpet.301.3.1179 10.7270/Q2QF8RFK 12023553 Kilts, JD; Connery, HS; Arrington, EG; Lewis, MM; Lawler, CP; Oxford, GS; O'Malley, KL; Todd, RD; Blake, BL; Nichols, DE; Mailman, RB University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E7O 7QPC,7WKW,7Y9U 8594 131342351 60833 C06374 ZINC00028113 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 183422 OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22) JXTHEWSKYLZVJC-UHFFFAOYSA-N 81777 CAS_132-66-1::NPA::NPA,(+)::NPA,(-)::NSC_8594 D(2) dopamine receptor Homo sapiens 2391 PDSP Ki 10.1124/jpet.301.3.1179 10.7270/Q2QF8RFK 12023553 Kilts, JD; Connery, HS; Arrington, EG; Lewis, MM; Lawler, CP; Oxford, GS; O'Malley, KL; Todd, RD; Blake, BL; Nichols, DE; Mailman, RB University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E7O 7QPC,7WKW,7Y9U 8594 131342351 60833 C06374 ZINC00028113 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 183423 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 2158 PDSP Ki 10.1124/jpet.301.3.1179 10.7270/Q2QF8RFK 12023553 Kilts, JD; Connery, HS; Arrington, EG; Lewis, MM; Lawler, CP; Oxford, GS; O'Malley, KL; Todd, RD; Blake, BL; Nichols, DE; Mailman, RB University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184619 CCCNC1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13) FASDKYOPVNHBLU-UHFFFAOYSA-N 50017550 CHEMBL76399::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX)::Pramipexole D(2) dopamine receptor Homo sapiens 1698.24 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 4885 103928818 CHEMBL76399 ZINC03831352 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184620 CCCN1CCC[C@@H]2Cc3nc(N)ncc3C[C@@H]12 InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m1/s1 TUFADSGTJUOBEH-ZWNOBZJWSA-N 50016017 (5aR,9aR)-6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine::(5aR,9aR)-6-propyl-5,5a,6,7,8,9,9a,10-octahydropyrido[2,3-g]quinazolin-2-amine::6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine(Quinelorane)::CHEMBL155731::Quinelorane::Quinerolane D(2) dopamine receptor Homo sapiens 707.95 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57242 103927698 CHEMBL155731 954 ZINC00005041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184621 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 1445.44 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184622 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Homo sapiens 933.25 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184623 Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 HGEYJZMMUGWEOT-UHFFFAOYSA-N 50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole D(2) dopamine receptor Homo sapiens 4.37 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 219050 103916479 48558 CHEMBL431367 52 ZINC01548439 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184624 Nc1nc2CCN(CC=C)CCc2s1 InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12) DHSSDEDRBUKTQY-UHFFFAOYSA-N 86053 B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374 D(2) dopamine receptor Homo sapiens 977.24 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5374 136352153 CHEMBL279085 ZINC00006644 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184625 CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1 JOAHPSVPXZTVEP-YXJHDRRASA-N 50017519 1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-urea::CHEMBL73151::Terguride D(2) dopamine receptor Homo sapiens 1.15 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 443951 103928787 CHEMBL73151 ZINC03811327 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184626 C[NH+](C)C1CCc2cc(O)c(O)cc2C1 InChI=1S/C12H17NO2/c1-13(2)10-4-3-8-6-11(14)12(15)7-9(8)5-10/h6-7,10,14-15H,3-5H2,1-2H3/p+1 JWLJBTDXCBIGBW-UHFFFAOYSA-O 50025206 (6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-ammonium::TL99 D(2) dopamine receptor Homo sapiens 67.61 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025206&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299913 103935110 ZINC05965207 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184627 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 34.67 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184628 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 5.01 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184629 CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(Cc3c[nH]c4cccc2c34)N(CC=C)C1 InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33) KORNTPPJEAJQIU-UHFFFAOYSA-N 86052 CAS_54746::Cabergoline::NSC_54746 D(2) dopamine receptor Homo sapiens 0.62 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2512 136352152 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184630 CCN(CC)C(=O)N[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18-/m1/s1 BKRGVLQUQGGVSM-RDTXWAMCSA-N 22867 1,1-diethyl-3-[(8beta)-6-methyl-9,10-didehydroergolin-8-yl]urea::3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),2,9,12(16),13-pentaen-4-yl]urea::8R-lisuride::LISURIDE D(2) dopamine receptor Homo sapiens 0.34 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11957615 49846681 ZINC03831002 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184631 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50028421 9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid::CHEMBL1275::LY-127809::PERGOLIDE MESYLATE::Pergolide::Permax D(2) dopamine receptor Homo sapiens 31.62 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103937709 8021 CHEMBL1275 DB01186 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184632 C(N1CCN(CC1)c1ncccn1)c1ccc2OCOc2c1 InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2 OQDPVLVUJFGPGQ-UHFFFAOYSA-N 85092 CAS_3605-01-4::NSC_4850::Piribedil D(2) dopamine receptor Homo sapiens 131.83 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4850 136351192 ZINC19537374 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184633 CCCNC1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13) FASDKYOPVNHBLU-UHFFFAOYSA-N 50017550 CHEMBL76399::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX)::Pramipexole D(2) dopamine receptor Homo sapiens 954.99 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 4885 103928818 CHEMBL76399 ZINC03831352 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184634 CCCN1CCC[C@@H]2Cc3nc(N)ncc3C[C@@H]12 InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m1/s1 TUFADSGTJUOBEH-ZWNOBZJWSA-N 50016017 (5aR,9aR)-6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine::(5aR,9aR)-6-propyl-5,5a,6,7,8,9,9a,10-octahydropyrido[2,3-g]quinazolin-2-amine::6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine(Quinelorane)::CHEMBL155731::Quinelorane::Quinerolane D(2) dopamine receptor Homo sapiens 316.23 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57242 103927698 CHEMBL155731 954 ZINC00005041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184635 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 891.25 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184636 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Homo sapiens 676.08 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184637 Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 HGEYJZMMUGWEOT-UHFFFAOYSA-N 50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole D(2) dopamine receptor Homo sapiens 2.82 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 219050 103916479 48558 CHEMBL431367 52 ZINC01548439 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184638 Nc1nc2CCN(CC=C)CCc2s1 InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12) DHSSDEDRBUKTQY-UHFFFAOYSA-N 86053 B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374 D(2) dopamine receptor Homo sapiens 616.60 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5374 136352153 CHEMBL279085 ZINC00006644 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184639 CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1 JOAHPSVPXZTVEP-YXJHDRRASA-N 50017519 1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-urea::CHEMBL73151::Terguride D(2) dopamine receptor Homo sapiens 0.81 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 443951 103928787 CHEMBL73151 ZINC03811327 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 184640 C[NH+](C)C1CCc2cc(O)c(O)cc2C1 InChI=1S/C12H17NO2/c1-13(2)10-4-3-8-6-11(14)12(15)7-9(8)5-10/h6-7,10,14-15H,3-5H2,1-2H3/p+1 JWLJBTDXCBIGBW-UHFFFAOYSA-O 50025206 (6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-ammonium::TL99 D(2) dopamine receptor Homo sapiens 7.22 PDSP Ki 10.1124/jpet.102.039867 10.7270/Q2MG7N2F 12388666 Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025206&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299913 103935110 ZINC05965207 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188399 COC(=O)c1occc1C[NH+]1CCC(CC1)c1c[nH]c2ccccc12 InChI=1S/C20H22N2O3/c1-24-20(23)19-15(8-11-25-19)13-22-9-6-14(7-10-22)17-12-21-18-5-3-2-4-16(17)18/h2-5,8,11-12,14,21H,6-7,9-10,13H2,1H3/p+1 MPZRVJWYRILMES-UHFFFAOYSA-O 86550 Piperidin-1-ium analog, 2 D(2) dopamine receptor Homo sapiens 1.3e+3 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 40114645 136352599 ZINC32879782 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188400 CC(CO)(CO)[NH2+]Cc1ccc(o1)-c1cc(Cl)ccc1Cl InChI=1S/C15H17Cl2NO3/c1-15(8-19,9-20)18-7-11-3-5-14(21-11)12-6-10(16)2-4-13(12)17/h2-6,18-20H,7-9H2,1H3/p+1 KEWAJFXKJCLQFC-UHFFFAOYSA-O 86551 Azanium analog, 3 D(2) dopamine receptor Homo sapiens >1.0e+4 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 41091195 136352600 ZINC09485749 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188401 O[C@@H](C[NH+]1CCN(CC1)c1nsc2ccccc12)c1cccs1 InChI=1S/C17H19N3OS2/c21-14(16-6-3-11-22-16)12-19-7-9-20(10-8-19)17-13-4-1-2-5-15(13)23-18-17/h1-6,11,14,21H,7-10,12H2/p+1/t14-/m0/s1 MENRZDOHDCGELK-AWEZNQCLSA-O 86552 Piperidin-1-ium analog, 4 D(2) dopamine receptor Homo sapiens 4e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86552&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53350236 136352601 ZINC19376162 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188402 OCCN1CC[NH+](CCOc2ccccc2-c2ccccc2)CC1 InChI=1S/C20H26N2O2/c23-16-14-21-10-12-22(13-11-21)15-17-24-20-9-5-4-8-19(20)18-6-2-1-3-7-18/h1-9,23H,10-17H2/p+1 BPLOTEOIDDVPGW-UHFFFAOYSA-O 86553 Piperidin-1-ium analog, 5 D(2) dopamine receptor Homo sapiens 4e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86553&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 28364960 136352602 ZINC19802469 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188403 Fc1ccc(cc1)-c1ccc(C[NH2+]Cc2cccnc2-n2cccn2)o1 InChI=1S/C20H17FN4O/c21-17-6-4-15(5-7-17)19-9-8-18(26-19)14-22-13-16-3-1-10-23-20(16)25-12-2-11-24-25/h1-12,22H,13-14H2/p+1 FEGZBVJAVUWCHP-UHFFFAOYSA-O 86554 Azanium analog, 6 D(2) dopamine receptor Homo sapiens 4.5e+3 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86554&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 38052390 136352603 ZINC30902249 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188404 Cc1cccc(c1)N1CC[NH+](C[C@@H](O)c2ccccc2F)CC1 InChI=1S/C19H23FN2O/c1-15-5-4-6-16(13-15)22-11-9-21(10-12-22)14-19(23)17-7-2-3-8-18(17)20/h2-8,13,19,23H,9-12,14H2,1H3/p+1/t19-/m1/s1 IYDUOKKAIDSDKG-LJQANCHMSA-O 86555 Piperazin-1-ium analog, 7 D(2) dopamine receptor Homo sapiens >1.0e+4 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86555&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53350238 136352604 ZINC26909988 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188405 C([NH2+]Cc1cccc2cccnc12)[C@@H]1COc2ccccc2O1 InChI=1S/C19H18N2O2/c1-2-9-18-17(8-1)22-13-16(23-18)12-20-11-15-6-3-5-14-7-4-10-21-19(14)15/h1-10,16,20H,11-13H2/p+1/t16-/m1/s1 HIYOMLKCLCXLLB-MRXNPFEDSA-O 86556 Azanium analog, 28 D(2) dopamine receptor Homo sapiens 9e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 40135445 136352605 ZINC32899493 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188406 C[NH+](C)[C@H](CNC(=O)c1cc(Cl)cc(Cl)c1)c1ccco1 InChI=1S/C15H16Cl2N2O2/c1-19(2)13(14-4-3-5-21-14)9-18-15(20)10-6-11(16)8-12(17)7-10/h3-8,13H,9H2,1-2H3,(H,18,20)/p+1/t13-/m1/s1 SQCJNQDAPVYVOP-CYBMUJFWSA-O 86557 Azanium analog, 29 D(2) dopamine receptor Homo sapiens 3.9e+3 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53350240 136352606 ZINC47648942 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188407 CCCNC(=O)C1CCC[NH+](CCOc2ccc(Cl)cc2)C1 InChI=1S/C17H25ClN2O2/c1-2-9-19-17(21)14-4-3-10-20(13-14)11-12-22-16-7-5-15(18)6-8-16/h5-8,14H,2-4,9-13H2,1H3,(H,19,21)/p+1 SNNSHVLURVGEND-UHFFFAOYSA-O 86558 Piperidin-1-ium analog, 30 D(2) dopamine receptor Homo sapiens >1.0e+4 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53350247 136352607 ZINC51003363 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188408 C[NH+](C)C(C)(C)CNC(=O)N1CCC[C@@H]1c1cccs1 InChI=1S/C15H25N3OS/c1-15(2,17(3)4)11-16-14(19)18-9-5-7-12(18)13-8-6-10-20-13/h6,8,10,12H,5,7,9,11H2,1-4H3,(H,16,19)/p+1/t12-/m1/s1 IMCUZGWEWOOBNS-GFCCVEGCSA-O 86559 Azanium analog, 31 D(2) dopamine receptor Homo sapiens >1.0e+4 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53350242 136352608 ZINC43190199 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188409 CC[NH+](CCC(=O)N1CCc2ccccc12)CC1CCCO1 InChI=1S/C18H26N2O2/c1-2-19(14-16-7-5-13-22-16)11-10-18(21)20-12-9-15-6-3-4-8-17(15)20/h3-4,6,8,16H,2,5,7,9-14H2,1H3/p+1 LNLCLUKMQMIOCU-UHFFFAOYSA-O 86560 Azanium analog, 32 D(2) dopamine receptor Homo sapiens 3.8e+3 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340645 136352609 ZINC51554972 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188427 OCC[NH2+]Cc1ccc(o1)-c1cc(Cl)cc(Cl)c1 InChI=1S/C13H13Cl2NO2/c14-10-5-9(6-11(15)7-10)13-2-1-12(18-13)8-16-3-4-17/h1-2,5-7,16-17H,3-4,8H2/p+1 BCNIROLOCVZMEX-UHFFFAOYSA-O 86561 Azanium analog, 53 D(2) dopamine receptor Homo sapiens 5.0e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7425172 136352610 ZINC04942886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188428 COCC[NH2+]Cc1ccc(o1)-c1cc(Cl)cc(Cl)c1 InChI=1S/C14H15Cl2NO2/c1-18-5-4-17-9-13-2-3-14(19-13)10-6-11(15)8-12(16)7-10/h2-3,6-8,17H,4-5,9H2,1H3/p+1 WGOKOPRYPYQGAG-UHFFFAOYSA-O 86562 Azanium analog, 54 D(2) dopamine receptor Homo sapiens 2.0e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7379361 136352611 ZINC04840966 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188429 C[NH2+]Cc1ccc(o1)-c1cc(Cl)cc(Cl)c1 InChI=1S/C12H11Cl2NO/c1-15-7-11-2-3-12(16-11)8-4-9(13)6-10(14)5-8/h2-6,15H,7H2,1H3/p+1 KVRNDHJOFNNVSM-UHFFFAOYSA-O 86563 Azanium analog, 55 D(2) dopamine receptor Homo sapiens 2.0e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7425173 136352612 ZINC04942887 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188430 CC(C)(CO)[NH2+]Cc1ccc(o1)-c1cc(Cl)cc(Cl)c1 InChI=1S/C15H17Cl2NO2/c1-15(2,9-19)18-8-13-3-4-14(20-13)10-5-11(16)7-12(17)6-10/h3-7,18-19H,8-9H2,1-2H3/p+1 ZJRRATGIBFUDNR-UHFFFAOYSA-O 86564 Azanium analog, 56 D(2) dopamine receptor Homo sapiens 3.0e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7380122 136352613 ZINC04842427 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188431 C[NH2+]Cc1ccc(o1)-c1cc(Cl)ccc1Cl InChI=1S/C12H11Cl2NO/c1-15-7-9-3-5-12(16-9)10-6-8(13)2-4-11(10)14/h2-6,15H,7H2,1H3/p+1 QRXLTSBBBBLZAZ-UHFFFAOYSA-O 86565 Azanium analog, 57 D(2) dopamine receptor Homo sapiens 2.60e+3 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7380086 136352614 ZINC04842372 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188432 OCC[NH2+]Cc1ccc(o1)-c1cc(Cl)ccc1Cl InChI=1S/C13H13Cl2NO2/c14-9-1-3-12(15)11(7-9)13-4-2-10(18-13)8-16-5-6-17/h1-4,7,16-17H,5-6,8H2/p+1 APPUUTIMRACOJA-UHFFFAOYSA-O 86566 Azanium analog, 58 D(2) dopamine receptor Homo sapiens 8.0e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7425146 136352615 ZINC04942870 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188433 CCC(CO)[NH2+]Cc1ccc(o1)-c1cc(Cl)ccc1Cl InChI=1S/C15H17Cl2NO2/c1-2-11(9-19)18-8-12-4-6-15(20-12)13-7-10(16)3-5-14(13)17/h3-7,11,18-19H,2,8-9H2,1H3/p+1 WHYMIYDTVBPNCA-UHFFFAOYSA-O 86567 Azanium analog, 59 D(2) dopamine receptor Homo sapiens 1.20e+3 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340646 136352616 ZINC04942872 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188434 C[C@H](O)C[NH2+]Cc1ccc(o1)-c1cc(Cl)ccc1Cl InChI=1S/C14H15Cl2NO2/c1-9(18)7-17-8-11-3-5-14(19-11)12-6-10(15)2-4-13(12)16/h2-6,9,17-18H,7-8H2,1H3/p+1/t9-/m0/s1 TUKUPVBGGWDOSX-VIFPVBQESA-O 86568 Azanium analog, 60 D(2) dopamine receptor Homo sapiens 6.0e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7425151 136352617 ZINC04942873 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188435 CC[NH2+]Cc1ccc(o1)-c1cc(Cl)ccc1Cl InChI=1S/C13H13Cl2NO/c1-2-16-8-10-4-6-13(17-10)11-7-9(14)3-5-12(11)15/h3-7,16H,2,8H2,1H3/p+1 YAFWOZQTNHUIBF-UHFFFAOYSA-O 86569 Azanium analog, 61 D(2) dopamine receptor Homo sapiens 2.0e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7425155 136352618 ZINC04942875 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188436 CC(C)[NH2+]Cc1ccc(o1)-c1cc(Cl)ccc1Cl InChI=1S/C14H15Cl2NO/c1-9(2)17-8-11-4-6-14(18-11)12-7-10(15)3-5-13(12)16/h3-7,9,17H,8H2,1-2H3/p+1 UBZILBONWIAPJX-UHFFFAOYSA-O 86570 Azanium analog, 62 D(2) dopamine receptor Homo sapiens 6.0e+2 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 41494863 136352619 ZINC10436244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188437 CC(C)(CO)[NH2+]Cc1ccc(o1)-c1cccc(c1)C(F)(F)F InChI=1S/C16H18F3NO2/c1-15(2,10-21)20-9-13-6-7-14(22-13)11-4-3-5-12(8-11)16(17,18)19/h3-8,20-21H,9-10H2,1-2H3/p+1 UKBHURMOKDKGIX-UHFFFAOYSA-O 86571 Azanium analog, 63 D(2) dopamine receptor Homo sapiens 1.70e+3 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 41493323 136352620 ZINC10434538 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188439 CCSc1nnc2N(CCCn12)C(=O)CN1CCOCC1 InChI=1S/C13H21N5O2S/c1-2-21-13-15-14-12-17(4-3-5-18(12)13)11(19)10-16-6-8-20-9-7-16/h2-10H2,1H3 OZYRXIRIATWFOZ-UHFFFAOYSA-N 86576 ZINC 17173082, 12 D(2) dopamine receptor Homo sapiens 6353.5 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11841225 136352625 ZINC17173082 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188440 CC(C)(C)[NH2+]Cc1ccc(o1)-c1ccccc1 InChI=1S/C15H19NO/c1-15(2,3)16-11-13-9-10-14(17-13)12-7-5-4-6-8-12/h4-10,16H,11H2,1-3H3/p+1 DPLPMJOBKFRDAY-UHFFFAOYSA-O 86589 ZINC 4942833, 65 D(2) dopamine receptor Homo sapiens 2896 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86589&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7425098 136352638 ZINC04942833 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188441 Clc1ccc(Cl)c(c1)-c1ccc(C[NH2+]C2CC2)o1 InChI=1S/C14H13Cl2NO/c15-9-1-5-13(16)12(7-9)14-6-4-11(18-14)8-17-10-2-3-10/h1,4-7,10,17H,2-3,8H2/p+1 VKAMNIMJPFNFIA-UHFFFAOYSA-O 86594 ZINC 4868730, 70 D(2) dopamine receptor Homo sapiens 6608 7.4 22.00 C Curated from the literature by BindingDB 10.1038/nchembio.662 10.7270/Q2TM78P6 21926995 aid1799703 Carlsson, J; Coleman, RG; Setola, V; Irwin, JJ; Fan, H; Schlessinger, A; Sali, A; Roth, BL; Shoichet, BK University of California San Francisco http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7394068 136352643 ZINC04868730 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189845 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1ccc(F)cc1F InChI=1S/C26H34F2N4O2/c1-18(2)34-25-6-4-3-5-24(25)32-15-13-31(14-16-32)21-10-8-20(9-11-21)29-26(33)30-23-12-7-19(27)17-22(23)28/h3-7,12,17-18,20-21H,8-11,13-16H2,1-2H3,(H2,29,30,33) NIQWPNGICRVKCM-UHFFFAOYSA-N 86850 1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041628::NSC_16041628 D(2) dopamine receptor Homo sapiens 0.69 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041628 136352899 ZINC53199479 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189846 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1ccc(F)cc1F InChI=1S/C26H34F2N4O2/c1-18(2)34-25-6-4-3-5-24(25)32-15-13-31(14-16-32)21-10-8-20(9-11-21)29-26(33)30-23-12-7-19(27)17-22(23)28/h3-7,12,17-18,20-21H,8-11,13-16H2,1-2H3,(H2,29,30,33) NIQWPNGICRVKCM-UHFFFAOYSA-N 86850 1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041628::NSC_16041628 D(2) dopamine receptor Homo sapiens 35.5 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041628 136352899 ZINC53199479 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189847 COc1ccc(NC(=O)NC2CCC(CC2)N2CCN(CC2)c2ccccc2OC(C)C)c(OC)c1 InChI=1S/C28H40N4O4/c1-20(2)36-26-8-6-5-7-25(26)32-17-15-31(16-18-32)22-11-9-21(10-12-22)29-28(33)30-24-14-13-23(34-3)19-27(24)35-4/h5-8,13-14,19-22H,9-12,15-18H2,1-4H3,(H2,29,30,33) HZACYYQCKLSFDB-UHFFFAOYSA-N 86854 1-(2,4-dimethoxyphenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041090::NSC_16041090 D(2) dopamine receptor Homo sapiens 892 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041090 136352903 ZINC53021603 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189848 COc1ccc(NC(=O)NC2CCC(CC2)N2CCN(CC2)c2ccccc2OC(C)C)c(OC)c1 InChI=1S/C28H40N4O4/c1-20(2)36-26-8-6-5-7-25(26)32-17-15-31(16-18-32)22-11-9-21(10-12-22)29-28(33)30-24-14-13-23(34-3)19-27(24)35-4/h5-8,13-14,19-22H,9-12,15-18H2,1-4H3,(H2,29,30,33) HZACYYQCKLSFDB-UHFFFAOYSA-N 86854 1-(2,4-dimethoxyphenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041090::NSC_16041090 D(2) dopamine receptor Homo sapiens 288 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041090 136352903 ZINC53021603 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189849 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1cc(F)ccc1F InChI=1S/C26H34F2N4O2/c1-18(2)34-25-6-4-3-5-24(25)32-15-13-31(14-16-32)21-10-8-20(9-11-21)29-26(33)30-23-17-19(27)7-12-22(23)28/h3-7,12,17-18,20-21H,8-11,13-16H2,1-2H3,(H2,29,30,33) NXJNUASOAQRPKJ-UHFFFAOYSA-N 86848 1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041629::NSC_16041629 D(2) dopamine receptor Homo sapiens 0.46 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041629 136352897 ZINC53026007 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189850 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1cc(F)ccc1F InChI=1S/C26H34F2N4O2/c1-18(2)34-25-6-4-3-5-24(25)32-15-13-31(14-16-32)21-10-8-20(9-11-21)29-26(33)30-23-17-19(27)7-12-22(23)28/h3-7,12,17-18,20-21H,8-11,13-16H2,1-2H3,(H2,29,30,33) NXJNUASOAQRPKJ-UHFFFAOYSA-N 86848 1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041629::NSC_16041629 D(2) dopamine receptor Homo sapiens 199 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041629 136352897 ZINC53026007 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189851 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1c(Cl)cccc1Cl InChI=1S/C26H34Cl2N4O2/c1-18(2)34-24-9-4-3-8-23(24)32-16-14-31(15-17-32)20-12-10-19(11-13-20)29-26(33)30-25-21(27)6-5-7-22(25)28/h3-9,18-20H,10-17H2,1-2H3,(H2,29,30,33) ZWNBANLWZZXEKO-UHFFFAOYSA-N 86852 1-(2,6-dichlorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041265::NSC_16041265 D(2) dopamine receptor Homo sapiens 4.7 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041265 136352901 ZINC53025979 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189852 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1c(Cl)cccc1Cl InChI=1S/C26H34Cl2N4O2/c1-18(2)34-24-9-4-3-8-23(24)32-16-14-31(15-17-32)20-12-10-19(11-13-20)29-26(33)30-25-21(27)6-5-7-22(25)28/h3-9,18-20H,10-17H2,1-2H3,(H2,29,30,33) ZWNBANLWZZXEKO-UHFFFAOYSA-N 86852 1-(2,6-dichlorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041265::NSC_16041265 D(2) dopamine receptor Homo sapiens 55 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041265 136352901 ZINC53025979 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189853 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1c(F)cccc1F InChI=1S/C26H34F2N4O2/c1-18(2)34-24-9-4-3-8-23(24)32-16-14-31(15-17-32)20-12-10-19(11-13-20)29-26(33)30-25-21(27)6-5-7-22(25)28/h3-9,18-20H,10-17H2,1-2H3,(H2,29,30,33) GRLCSEWTOACLTP-UHFFFAOYSA-N 86845 1-(2,6-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041630::NSC_16041630 D(2) dopamine receptor Homo sapiens 2.40 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041630 136352894 ZINC53050488 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189854 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1c(F)cccc1F InChI=1S/C26H34F2N4O2/c1-18(2)34-24-9-4-3-8-23(24)32-16-14-31(15-17-32)20-12-10-19(11-13-20)29-26(33)30-25-21(27)6-5-7-22(25)28/h3-9,18-20H,10-17H2,1-2H3,(H2,29,30,33) GRLCSEWTOACLTP-UHFFFAOYSA-N 86845 1-(2,6-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041630::NSC_16041630 D(2) dopamine receptor Homo sapiens 22 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041630 136352894 ZINC53050488 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189855 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1ccccc1Cl InChI=1S/C26H35ClN4O2/c1-19(2)33-25-10-6-5-9-24(25)31-17-15-30(16-18-31)21-13-11-20(12-14-21)28-26(32)29-23-8-4-3-7-22(23)27/h3-10,19-21H,11-18H2,1-2H3,(H2,28,29,32) LHOVFJRBCVNIQC-UHFFFAOYSA-N 86851 1-(2-chlorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041263::NSC_16041263 D(2) dopamine receptor Homo sapiens 33 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041263 136352900 ZINC53026018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189856 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1ccccc1Cl InChI=1S/C26H35ClN4O2/c1-19(2)33-25-10-6-5-9-24(25)31-17-15-30(16-18-31)21-13-11-20(12-14-21)28-26(32)29-23-8-4-3-7-22(23)27/h3-10,19-21H,11-18H2,1-2H3,(H2,28,29,32) LHOVFJRBCVNIQC-UHFFFAOYSA-N 86851 1-(2-chlorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041263::NSC_16041263 D(2) dopamine receptor Homo sapiens 878 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041263 136352900 ZINC53026018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189857 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1ccc(F)c(F)c1 InChI=1S/C26H34F2N4O2/c1-18(2)34-25-6-4-3-5-24(25)32-15-13-31(14-16-32)21-10-7-19(8-11-21)29-26(33)30-20-9-12-22(27)23(28)17-20/h3-6,9,12,17-19,21H,7-8,10-11,13-16H2,1-2H3,(H2,29,30,33) PIKIDBPDYRQPFX-UHFFFAOYSA-N 86843 1-(3,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041092::NSC_16041092 D(2) dopamine receptor Homo sapiens 54 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041092 136352892 ZINC53025953 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189858 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1ccc(F)c(F)c1 InChI=1S/C26H34F2N4O2/c1-18(2)34-25-6-4-3-5-24(25)32-15-13-31(14-16-32)21-10-7-19(8-11-21)29-26(33)30-20-9-12-22(27)23(28)17-20/h3-6,9,12,17-19,21H,7-8,10-11,13-16H2,1-2H3,(H2,29,30,33) PIKIDBPDYRQPFX-UHFFFAOYSA-N 86843 1-(3,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041092::NSC_16041092 D(2) dopamine receptor Homo sapiens 127 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041092 136352892 ZINC53025953 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189859 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1cccc(Cl)c1 InChI=1S/C26H35ClN4O2/c1-19(2)33-25-9-4-3-8-24(25)31-16-14-30(15-17-31)23-12-10-21(11-13-23)28-26(32)29-22-7-5-6-20(27)18-22/h3-9,18-19,21,23H,10-17H2,1-2H3,(H2,28,29,32) MHMZJEYRSGRQHH-UHFFFAOYSA-N 86853 1-(3-chlorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041264::NSC_16041264 D(2) dopamine receptor Homo sapiens 84 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041264 136352902 ZINC53025955 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189860 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1cccc(Cl)c1 InChI=1S/C26H35ClN4O2/c1-19(2)33-25-9-4-3-8-24(25)31-16-14-30(15-17-31)23-12-10-21(11-13-23)28-26(32)29-22-7-5-6-20(27)18-22/h3-9,18-19,21,23H,10-17H2,1-2H3,(H2,28,29,32) MHMZJEYRSGRQHH-UHFFFAOYSA-N 86853 1-(3-chlorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041264::NSC_16041264 D(2) dopamine receptor Homo sapiens 108 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041264 136352902 ZINC53025955 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189861 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)NCc1cccc(F)c1 InChI=1S/C27H37FN4O2/c1-20(2)34-26-9-4-3-8-25(26)32-16-14-31(15-17-32)24-12-10-23(11-13-24)30-27(33)29-19-21-6-5-7-22(28)18-21/h3-9,18,20,23-24H,10-17,19H2,1-2H3,(H2,29,30,33) QJFXDZVKRFQGQF-UHFFFAOYSA-N 86849 1-(3-fluorobenzyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041091::NSC_16041091 D(2) dopamine receptor Homo sapiens 120 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86849&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041091 136352898 ZINC53025965 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189862 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)NCc1cccc(F)c1 InChI=1S/C27H37FN4O2/c1-20(2)34-26-9-4-3-8-25(26)32-16-14-31(15-17-32)24-12-10-23(11-13-24)30-27(33)29-19-21-6-5-7-22(28)18-21/h3-9,18,20,23-24H,10-17,19H2,1-2H3,(H2,29,30,33) QJFXDZVKRFQGQF-UHFFFAOYSA-N 86849 1-(3-fluorobenzyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041091::NSC_16041091 D(2) dopamine receptor Homo sapiens 183 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86849&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041091 136352898 ZINC53025965 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189863 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1c(Cl)cc(Cl)cc1Cl InChI=1S/C26H33Cl3N4O2/c1-17(2)35-24-6-4-3-5-23(24)33-13-11-32(12-14-33)20-9-7-19(8-10-20)30-26(34)31-25-21(28)15-18(27)16-22(25)29/h3-6,15-17,19-20H,7-14H2,1-2H3,(H2,30,31,34) IEMSLTPIYQZIGD-UHFFFAOYSA-N 86847 1-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-3-(2,4,6-trichlorophenyl)urea::CAS_16041449::NSC_16041449 D(2) dopamine receptor Homo sapiens 6.5 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041449 136352896 ZINC53025963 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189864 CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1c(Cl)cc(Cl)cc1Cl InChI=1S/C26H33Cl3N4O2/c1-17(2)35-24-6-4-3-5-23(24)33-13-11-32(12-14-33)20-9-7-19(8-10-20)30-26(34)31-25-21(28)15-18(27)16-22(25)29/h3-6,15-17,19-20H,7-14H2,1-2H3,(H2,30,31,34) IEMSLTPIYQZIGD-UHFFFAOYSA-N 86847 1-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-3-(2,4,6-trichlorophenyl)urea::CAS_16041449::NSC_16041449 D(2) dopamine receptor Homo sapiens 103 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041449 136352896 ZINC53025963 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189865 COc1ccccc1NC(=O)NC1CCC(CC1)N1CCN(CC1)c1ccccc1OC(C)C InChI=1S/C27H38N4O3/c1-20(2)34-26-11-7-5-9-24(26)31-18-16-30(17-19-31)22-14-12-21(13-15-22)28-27(32)29-23-8-4-6-10-25(23)33-3/h4-11,20-22H,12-19H2,1-3H3,(H2,28,29,32) MVVUJPWQKLPZEE-UHFFFAOYSA-N 86855 1-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-3-(2-methoxyphenyl)urea::CAS_16040907::NSC_16040907 D(2) dopamine receptor Homo sapiens 921 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16040907 136352904 ZINC53050526 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189866 COc1ccccc1NC(=O)NC1CCC(CC1)N1CCN(CC1)c1ccccc1OC(C)C InChI=1S/C27H38N4O3/c1-20(2)34-26-11-7-5-9-24(26)31-18-16-30(17-19-31)22-14-12-21(13-15-22)28-27(32)29-23-8-4-6-10-25(23)33-3/h4-11,20-22H,12-19H2,1-3H3,(H2,28,29,32) MVVUJPWQKLPZEE-UHFFFAOYSA-N 86855 1-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-3-(2-methoxyphenyl)urea::CAS_16040907::NSC_16040907 D(2) dopamine receptor Homo sapiens 390 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16040907 136352904 ZINC53050526 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189867 COc1ccc(Cl)cc1NC(=O)NC1CCC(CC1)N1CCN(CC1)c1ccccc1OC(C)C InChI=1S/C27H37ClN4O3/c1-19(2)35-26-7-5-4-6-24(26)32-16-14-31(15-17-32)22-11-9-21(10-12-22)29-27(33)30-23-18-20(28)8-13-25(23)34-3/h4-8,13,18-19,21-22H,9-12,14-17H2,1-3H3,(H2,29,30,33) AVIOZEGAUFSOTR-UHFFFAOYSA-N 86844 1-(5-chloro-2-methoxyphenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041451::NSC_16041451 D(2) dopamine receptor Homo sapiens 1.20 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041451 136352893 ZINC53050668 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189868 COc1ccc(Cl)cc1NC(=O)NC1CCC(CC1)N1CCN(CC1)c1ccccc1OC(C)C InChI=1S/C27H37ClN4O3/c1-19(2)35-26-7-5-4-6-24(26)32-16-14-31(15-17-32)22-11-9-21(10-12-22)29-27(33)30-23-18-20(28)8-13-25(23)34-3/h4-8,13,18-19,21-22H,9-12,14-17H2,1-3H3,(H2,29,30,33) AVIOZEGAUFSOTR-UHFFFAOYSA-N 86844 1-(5-chloro-2-methoxyphenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041451::NSC_16041451 D(2) dopamine receptor Homo sapiens 99 PDSP Ki 10.1016/j.bmcl.2007.11.068 10.7270/Q27H1H5S 18055202 Chiu, G; Li, S; Connolly, PJ; Pulito, V; Liu, J; Middleton, SA Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16041451 136352893 ZINC53050668 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188848 CC(C)C(=O)N(C1CC(C)N(C(=O)c2ccccc2)c2ccccc12)c1ccccc1 InChI=1S/C27H28N2O2/c1-19(2)26(30)29(22-14-8-5-9-15-22)25-18-20(3)28(24-17-11-10-16-23(24)25)27(31)21-12-6-4-7-13-21/h4-17,19-20,25H,18H2,1-3H3 FTCWKSGDHXCEMZ-UHFFFAOYSA-N 86692 K117 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.104.081539 10.7270/Q2RN36FF 15798001 Mimura, H; Ikemura, T; Kotera, O; Sawada, M; Tashiro, S; Fuse, E; Ueno, K; Manabe, H; Ohshima, E; Karasawa, A; Miyaji, H Kyowa Hakko Kogyo Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3723424 136352741 ZINC13897246 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188849 CCC(=O)N1C(C)CC(N(C(C)=O)c2ccccc2)c2ccccc12 InChI=1S/C21H24N2O2/c1-4-21(25)22-15(2)14-20(18-12-8-9-13-19(18)22)23(16(3)24)17-10-6-5-7-11-17/h5-13,15,20H,4,14H2,1-3H3 DRQJSDYVORTCEY-UHFFFAOYSA-N 86693 K376 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.104.081539 10.7270/Q2RN36FF 15798001 Mimura, H; Ikemura, T; Kotera, O; Sawada, M; Tashiro, S; Fuse, E; Ueno, K; Manabe, H; Ohshima, E; Karasawa, A; Miyaji, H Kyowa Hakko Kogyo Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4271604 136352742 ZINC00031401 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188850 CC1CC(N(C(=O)C2CC2)c2ccccc2)c2ccccc2N1C(=O)c1ccccc1 InChI=1S/C27H26N2O2/c1-19-18-25(29(27(31)21-16-17-21)22-12-6-3-7-13-22)23-14-8-9-15-24(23)28(19)26(30)20-10-4-2-5-11-20/h2-15,19,21,25H,16-18H2,1H3 VGFZCFWVSYIXEK-UHFFFAOYSA-N 86691 K604 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.104.081539 10.7270/Q2RN36FF 15798001 Mimura, H; Ikemura, T; Kotera, O; Sawada, M; Tashiro, S; Fuse, E; Ueno, K; Manabe, H; Ohshima, E; Karasawa, A; Miyaji, H Kyowa Hakko Kogyo Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86691&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340709 136352740 ZINC27098753 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187665 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.41 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187666 OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 InChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 LLBLNMUONVVVPG-UHFFFAOYSA-N 50050467 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol::3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole::4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol::CHEMBL445102::L-741626::L741,626 D(2) dopamine receptor Homo sapiens 2.95 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133633 103947637 CHEMBL445102 177 ZINC00006788 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187667 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Homo sapiens 933.25 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187668 CCCC1CC2=C(OCC=N2)C2(NC(=O)CC(O)=O)C=CCCC12 InChI=1S/C18H24N2O4/c1-2-5-12-10-14-17(24-9-8-19-14)18(7-4-3-6-13(12)18)20-15(21)11-16(22)23/h4,7-8,12-13H,2-3,5-6,9-11H2,1H3,(H,20,21)(H,22,23) BSBXGNLUQCQTGK-UHFFFAOYSA-N 86474 (+-)-trans-3,4,4a,5,6,10b-hexahydro-9-carbamoyl- 4-propyl-2H-naphth[1,2-b]-1,4-oxazine::S31411 (+-) D(2) dopamine receptor Homo sapiens 1380.38 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91899089 136352523 C01656 ZINC87723425 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187669 CCCN1CCO[C@H]2[C@H]1CCc1ccc(cc21)C(N)=O InChI=1S/C16H22N2O2/c1-2-7-18-8-9-20-15-13-10-12(16(17)19)4-3-11(13)5-6-14(15)18/h3-4,10,14-15H,2,5-9H2,1H3,(H2,17,19)/t14-,15-/m1/s1 XKTRZPQOQOCNJU-HUUCEWRRSA-N 86473 S32504 (+) D(2) dopamine receptor Homo sapiens 512.86 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15389743 136352522 ZINC40819117 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187670 CCCC1CC2=C(OCC=N2)[C@]2(NC(=O)CC(O)=O)C=CCCC12 InChI=1S/C18H24N2O4/c1-2-5-12-10-14-17(24-9-8-19-14)18(7-4-3-6-13(12)18)20-15(21)11-16(22)23/h4,7-8,12-13H,2-3,5-6,9-11H2,1H3,(H,20,21)(H,22,23)/t12?,13?,18-/m0/s1 BSBXGNLUQCQTGK-KJBLDROHSA-N 86472 (-)-trans-3,4,4a,5,6,10b-hexahydro-9-carbamoyl- 4-propyl-2H-naphth[1,2-b]-1,4-oxazine::S32601 (-) D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91899088 136352521 C01656 ZINC87723419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187671 O=C(NCCCCN1C[C@@H]2COc3ccc(cc3[C@H]2C1)C#N)c1ccc(cc1)-c1ccccc1 InChI=1S/C29H29N3O2/c30-17-21-8-13-28-26(16-21)27-19-32(18-25(27)20-34-28)15-5-4-14-31-29(33)24-11-9-23(10-12-24)22-6-2-1-3-7-22/h1-3,6-13,16,25,27H,4-5,14-15,18-20H2,(H,31,33)/t25-,27+/m1/s1 QQJHRQZZCNYDMX-VPUSJEBWSA-N 85672 S33084 D(2) dopamine receptor Homo sapiens 29.51 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9868452 136351772 ZINC03941217 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187672 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Homo sapiens 676.08 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187673 CCCC1CC2=C(OCC=N2)C2(NC(=O)CC(O)=O)C=CCCC12 InChI=1S/C18H24N2O4/c1-2-5-12-10-14-17(24-9-8-19-14)18(7-4-3-6-13(12)18)20-15(21)11-16(22)23/h4,7-8,12-13H,2-3,5-6,9-11H2,1H3,(H,20,21)(H,22,23) BSBXGNLUQCQTGK-UHFFFAOYSA-N 86474 (+-)-trans-3,4,4a,5,6,10b-hexahydro-9-carbamoyl- 4-propyl-2H-naphth[1,2-b]-1,4-oxazine::S31411 (+-) D(2) dopamine receptor Homo sapiens 794.33 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91899089 136352523 C01656 ZINC87723425 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187674 CCCN1CCO[C@H]2[C@H]1CCc1ccc(cc21)C(N)=O InChI=1S/C16H22N2O2/c1-2-7-18-8-9-20-15-13-10-12(16(17)19)4-3-11(13)5-6-14(15)18/h3-4,10,14-15H,2,5-9H2,1H3,(H2,17,19)/t14-,15-/m1/s1 XKTRZPQOQOCNJU-HUUCEWRRSA-N 86473 S32504 (+) D(2) dopamine receptor Homo sapiens 354.81 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15389743 136352522 ZINC40819117 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187675 CCCC1CC2=C(OCC=N2)[C@]2(NC(=O)CC(O)=O)C=CCCC12 InChI=1S/C18H24N2O4/c1-2-5-12-10-14-17(24-9-8-19-14)18(7-4-3-6-13(12)18)20-15(21)11-16(22)23/h4,7-8,12-13H,2-3,5-6,9-11H2,1H3,(H,20,21)(H,22,23)/t12?,13?,18-/m0/s1 BSBXGNLUQCQTGK-KJBLDROHSA-N 86472 (-)-trans-3,4,4a,5,6,10b-hexahydro-9-carbamoyl- 4-propyl-2H-naphth[1,2-b]-1,4-oxazine::S32601 (-) D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91899088 136352521 C01656 ZINC87723419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188976 C[C@H](CN(C(=O)c1ccc(cc1)C#N)c1ccccn1)N1CCN(CC1)c1cccc2OCCOc12 InChI=1S/C28H29N5O3/c1-21(31-13-15-32(16-14-31)24-5-4-6-25-27(24)36-18-17-35-25)20-33(26-7-2-3-12-30-26)28(34)23-10-8-22(19-29)9-11-23/h2-12,21H,13-18,20H2,1H3/t21-/m1/s1 NRPQELCNMADTOZ-OAQYLSRUSA-N 50166903 4-Cyano-N-{(R)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide::CHEMBL372205::Lecozotan D(2) dopamine receptor Homo sapiens 1548 PDSP Ki 10.1124/jpet.105.086363 10.7270/Q2057DJ4 15951399 Schechter, LE; Smith, DL; Rosenzweig-Lipson, S; Sukoff, SJ; Dawson, LA; Marquis, K; Jones, D; Piesla, M; Andree, T; Nawoschik, S; Harder, JA; Womack, MD; Buccafusco, J; Terry, AV; Hoebel, B; Rada, P; Kelly, M; Abou-Gharbia, M; Barrett, JE; Childers, W Wyeth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166903&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10116877 104052298 CHEMBL372205 ZINC12914519 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 190338 CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) NTJOBXMMWNYJFB-UHFFFAOYSA-N 81790 Amisulpride::CAS_71675-85-9::NSC_2159::US10167256, Amisulpride::US10259786, Amisulpride D(2) dopamine receptor Homo sapiens 3 PDSP Ki 10.1007/s00213-009-1521-8 10.7270/Q2TB15G7 19337725 Abbas, AI; Hedlund, PB; Huang, XP; Tran, TB; Meltzer, HY; Roth, BL Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2159 131342364 64045 DB06288 963 ZINC01846088 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187901 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 49.9 PDSP Ki 10.1124/jpet.104.066688 10.7270/Q28S4NH4 15102927 Vanover, KE; Harvey, SC; Son, T; Bradley, SR; Kold, H; Makhay, M; Veinbergs, I; Spalding, TA; Weiner, DM; Andersson, CM; Tolf, BR; Brann, MR; Hacksell, U; Davis, RE ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 187902 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.7 PDSP Ki 10.1124/jpet.104.066688 10.7270/Q28S4NH4 15102927 Vanover, KE; Harvey, SC; Son, T; Bradley, SR; Kold, H; Makhay, M; Veinbergs, I; Spalding, TA; Weiner, DM; Andersson, CM; Tolf, BR; Brann, MR; Hacksell, U; Davis, RE ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189128 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Homo sapiens 1 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189129 Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1 InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2 QWGDMFLQWFTERH-UHFFFAOYSA-N 22870 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine::Amoxapine::Asendin::CHEMBL1113::Demolox D(2) dopamine receptor Homo sapiens 3.6 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2170 49846684 2675 CHEMBL1113 DB00543 201 ZINC00000931 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189130 Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1 InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2 QWGDMFLQWFTERH-UHFFFAOYSA-N 22870 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine::Amoxapine::Asendin::CHEMBL1113::Demolox D(2) dopamine receptor Homo sapiens 38 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2170 49846684 2675 CHEMBL1113 DB00543 201 ZINC00000931 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189131 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 4.4 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189132 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Br)cc1 InChI=1S/C21H23BrFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 RKLNONIVDFXQRX-UHFFFAOYSA-N 81484 BROMPERIDOL::Bromoperidol::CAS_2448::NSC_2448 D(2) dopamine receptor Homo sapiens 1 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2448 131342058 ZINC00601270 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189133 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Br)cc1 InChI=1S/C21H23BrFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 RKLNONIVDFXQRX-UHFFFAOYSA-N 81484 BROMPERIDOL::Bromoperidol::CAS_2448::NSC_2448 D(2) dopamine receptor Homo sapiens 2.1 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2448 131342058 ZINC00601270 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189134 CC(C)(C)C1(O)CCN2CC3c4ccccc4CCc4cccc(C2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3 ZZJYIKPMDIWRSN-UHFFFAOYSA-N 86721 BUTACLAMOL::CAS_51152-91-1::NSC_37459::US11147820, Compound Butaclamol D(2) dopamine receptor Homo sapiens 0.4 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1224 136352770 ZINC03870317 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189135 CC(C)(C)C1(O)CCN2CC3c4ccccc4CCc4cccc(C2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3 ZZJYIKPMDIWRSN-UHFFFAOYSA-N 86721 BUTACLAMOL::CAS_51152-91-1::NSC_37459::US11147820, Compound Butaclamol D(2) dopamine receptor Homo sapiens 0.3 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1224 136352770 ZINC03870317 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189136 CCN(CC)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H23ClN2S/c1-3-21(4-2)12-7-13-22-16-8-5-6-9-18(16)23-19-11-10-15(20)14-17(19)22/h5-6,8-11,14H,3-4,7,12-13H2,1-2H3 DBOUGBAQLIXZLV-UHFFFAOYSA-N 86724 CAS_84-01-5::NSC_65750::chlorproethazine D(2) dopamine receptor Homo sapiens 11 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65750 136352773 ZINC00001135 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189137 CCN(CC)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H23ClN2S/c1-3-21(4-2)12-7-13-22-16-8-5-6-9-18(16)23-19-11-10-15(20)14-17(19)22/h5-6,8-11,14H,3-4,7,12-13H2,1-2H3 DBOUGBAQLIXZLV-UHFFFAOYSA-N 86724 CAS_84-01-5::NSC_65750::chlorproethazine D(2) dopamine receptor Homo sapiens 10 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65750 136352773 ZINC00001135 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189138 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 8.1 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189139 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 1.7 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189140 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 72 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189141 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Homo sapiens 71 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189142 OCCN1CCN(CCC=C2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2 NJMYODHXAKYRHW-UHFFFAOYSA-N 86722 CAS_53772-82-0::CAS_53772-85-3::FLUPENTHIXOL, Alpha::Flupenthixol, Beta::NSC_17012 D(2) dopamine receptor Homo sapiens 0.5 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86722&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 136352771 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189143 OCCN1CCN(CCC=C2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2 NJMYODHXAKYRHW-UHFFFAOYSA-N 86722 CAS_53772-82-0::CAS_53772-85-3::FLUPENTHIXOL, Alpha::Flupenthixol, Beta::NSC_17012 D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86722&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 136352771 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189144 OCCN1CCN(CCC=C2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2 NJMYODHXAKYRHW-UHFFFAOYSA-N 86722 CAS_53772-82-0::CAS_53772-85-3::FLUPENTHIXOL, Alpha::Flupenthixol, Beta::NSC_17012 D(2) dopamine receptor Homo sapiens 21 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86722&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 136352771 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189145 OCCN1CCN(CCC=C2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2 NJMYODHXAKYRHW-UHFFFAOYSA-N 86722 CAS_53772-82-0::CAS_53772-85-3::FLUPENTHIXOL, Alpha::Flupenthixol, Beta::NSC_17012 D(2) dopamine receptor Homo sapiens 17 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86722&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 136352771 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189146 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Homo sapiens 0.4 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189147 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189148 Fc1ccc(cc1)C(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1 InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35) QOYHHIBFXOOADH-UHFFFAOYSA-N 26948 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL46516::FLUSPIRILENE::NCGC00015424::cid_3396::med.21724, Compound Fluspirilene::spiropiperidine analogue, 1 D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3396 57298659 CHEMBL46516 DB04842 85 ZINC00537755 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189149 Fc1ccc(cc1)C(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1 InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35) QOYHHIBFXOOADH-UHFFFAOYSA-N 26948 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL46516::FLUSPIRILENE::NCGC00015424::cid_3396::med.21724, Compound Fluspirilene::spiropiperidine analogue, 1 D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3396 57298659 CHEMBL46516 DB04842 85 ZINC00537755 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189150 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.6 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189151 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.8 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189152 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OGJGQVFWEPNYSB-UHFFFAOYSA-N 85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853 D(2) dopamine receptor Homo sapiens 343 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L74 6IQL 5311200 136351193 CHEMBL555670CHEMBL267014 3303 ZINC25760037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189153 CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 DKMFBWQBDIGMHM-UHFFFAOYSA-N 81771 CAS_3575-80-2::MELPERONE::NSC_15387 D(2) dopamine receptor Homo sapiens 3.6 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15387 131342345 DB09224 ZINC00001672 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189154 CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 SLVMESMUVMCQIY-UHFFFAOYSA-N 50131440 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23 D(2) dopamine receptor Homo sapiens 4.3 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4078 104022598 6780 CHEMBL1088 DB00933 7227 C07143 ZINC03831042 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189155 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Homo sapiens 20 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189156 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Homo sapiens 3.8 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189157 Cc1ccc(cc1)C1(O)CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C22H26FNO2/c1-17-4-8-19(9-5-17)22(26)12-15-24(16-13-22)14-2-3-21(25)18-6-10-20(23)11-7-18/h4-11,26H,2-3,12-16H2,1H3 AGAHNABIDCTLHW-UHFFFAOYSA-N 81486 CAS_1050-79-9::MOPERONE::NSC_4249 D(2) dopamine receptor Homo sapiens 0.7 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4249 131342060 ZINC00538026 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189158 Cc1ccc(cc1)C1(O)CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C22H26FNO2/c1-17-4-8-19(9-5-17)22(26)12-15-24(16-13-22)14-2-3-21(25)18-6-10-20(23)11-7-18/h4-11,26H,2-3,12-16H2,1H3 AGAHNABIDCTLHW-UHFFFAOYSA-N 81486 CAS_1050-79-9::MOPERONE::NSC_4249 D(2) dopamine receptor Homo sapiens 1 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4249 131342060 ZINC00538026 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189159 Clc1ccc2N=c3ccccc3=C(Nc2c1)N1CCNCC1 InChI=1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19,21H,7-10H2 HESZUPIXRNZIOI-UHFFFAOYSA-N 82478 CAS_2820::N-DESMETHYLCLOZAPINE::NSC_2820 D(2) dopamine receptor Homo sapiens 89 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82478&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2820 136350449 333 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189160 Cc1cccn2c1nc(C)c(CCN1CCC(CC1)c1noc3cc(F)ccc13)c2=O InChI=1S/C24H25FN4O2/c1-15-4-3-10-29-23(15)26-16(2)19(24(29)30)9-13-28-11-7-17(8-12-28)22-20-6-5-18(25)14-21(20)31-27-22/h3-6,10,14,17H,7-9,11-13H2,1-2H3 ZZQNEJILGNNOEP-UHFFFAOYSA-N 84734 CAS_129029-23-8::NSC_71351::Ocaperidone D(2) dopamine receptor Homo sapiens 0.4 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71351 136350834 46 ZINC00538119 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189161 Cc1cccn2c1nc(C)c(CCN1CCC(CC1)c1noc3cc(F)ccc13)c2=O InChI=1S/C24H25FN4O2/c1-15-4-3-10-29-23(15)26-16(2)19(24(29)30)9-13-28-11-7-17(8-12-28)22-20-6-5-18(25)14-21(20)31-27-22/h3-6,10,14,17H,7-9,11-13H2,1-2H3 ZZQNEJILGNNOEP-UHFFFAOYSA-N 84734 CAS_129029-23-8::NSC_71351::Ocaperidone D(2) dopamine receptor Homo sapiens 0.1 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71351 136350834 46 ZINC00538119 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189162 CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3 XRYLGRGAWQSVQW-UHFFFAOYSA-N 22872 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate::1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine::1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine::CHEMBL64249::CLOROTEPINE (+)::CLOROTEPINE(-)::Clothepin::OCTOCLOTHEPIN,(+)::OCTOCLOTHEPIN,(-)::Octoclothepin::Octoclothepine D(2) dopamine receptor Homo sapiens 0.7 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1238 49846686 CHEMBL64249 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189163 CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3 XRYLGRGAWQSVQW-UHFFFAOYSA-N 22872 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate::1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine::1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine::CHEMBL64249::CLOROTEPINE (+)::CLOROTEPINE(-)::Clothepin::OCTOCLOTHEPIN,(+)::OCTOCLOTHEPIN,(-)::Octoclothepin::Octoclothepine D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1238 49846686 CHEMBL64249 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189164 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Homo sapiens 106 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189165 Cc1cc2c(Nc3ccccc3N=C2N2CCNCC2)s1 InChI=1S/C16H18N4S/c1-11-10-12-15(20-8-6-17-7-9-20)18-13-4-2-3-5-14(13)19-16(12)21-11/h2-5,10,17,19H,6-9H2,1H3 FHPIXVHJEIZKJW-UHFFFAOYSA-N 50240701 2-Methyl-10-piperazin-1-yl-4H-3-thia-4,9-diaza-benzo[f]azulene::4-Desmethylolanzapine::CHEMBL1125::desmethylolanzapine::olanzapine, N-desmethyl D(2) dopamine receptor Homo sapiens 32 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240701&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948206 104098423 CHEMBL1125 ZINC22055590 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189166 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 2.4 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189167 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Homo sapiens 0.5 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189168 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 78434 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499 D(2) dopamine receptor Homo sapiens 1.1 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P77 3M0W 4917 252655190 8435 DB00433 C07403 ZINC19796018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189169 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 78434 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499 D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P77 3M0W 4917 252655190 8435 DB00433 C07403 ZINC19796018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189170 CN(C)CCCN1c2ccccc2Sc2ccccc12 InChI=1S/C17H20N2S/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19/h3-6,8-11H,7,12-13H2,1-2H3 ZGUGWUXLJSTTMA-UHFFFAOYSA-N 67545 N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride::PROMAZINE::SR-01000000228-4::US9504692, Promazine::cid_5887::dimethyl(3-phenothiazin-10-ylpropyl)amine;hydrochloride D(2) dopamine receptor Homo sapiens 300 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P2Z 7LGI,4MA7 4926 252645840 DB00420 C07379 ZINC00010402 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189171 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 16 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189172 CCN1CCCC1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21) WAOQONBSWFLFPE-UHFFFAOYSA-N 50010637 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::3,5-dichloro-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-hydroxy-6-methoxybenzamide::RACLOPRIDE D(2) dopamine receptor Homo sapiens 2.4 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5118 103923411 94 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189173 CCN1CCCC1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21) WAOQONBSWFLFPE-UHFFFAOYSA-N 50010637 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::3,5-dichloro-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-hydroxy-6-methoxybenzamide::RACLOPRIDE D(2) dopamine receptor Homo sapiens 0.5 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5118 103923411 94 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189174 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Homo sapiens 105 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189175 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Homo sapiens 16 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189176 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 0.6 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189177 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 0.3 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189178 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189179 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Homo sapiens 2.7 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189180 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.03 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189181 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.3 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189182 CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)(=O)=O InChI=1S/C21H26N2O2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)26-21-11-10-17(15-19(21)23)27(2,24)25/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 FLGCRGJDQJIJAW-UHFFFAOYSA-N 86723 CAS_14759-06-9::NSC_31765::sulforidazine D(2) dopamine receptor Homo sapiens 0.3 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86723&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 31765 136352772 ZINC02015244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189183 CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)(=O)=O InChI=1S/C21H26N2O2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)26-21-11-10-17(15-19(21)23)27(2,24)25/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 FLGCRGJDQJIJAW-UHFFFAOYSA-N 86723 CAS_14759-06-9::NSC_31765::sulforidazine D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86723&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 31765 136352772 ZINC02015244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189184 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 8.6 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189185 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Homo sapiens 11 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189186 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC InChI=1S/C17H26N2O4S/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20) UNRHXEPDKXPRTM-UHFFFAOYSA-N 86720 CAS_53583-79-2::NSC_5357::Sultopride D(2) dopamine receptor Homo sapiens 1.6 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5357 136352769 C11708 ZINC00967922 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189187 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC InChI=1S/C17H26N2O4S/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20) UNRHXEPDKXPRTM-UHFFFAOYSA-N 86720 CAS_53583-79-2::NSC_5357::Sultopride D(2) dopamine receptor Homo sapiens 4.5 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5357 136352769 C11708 ZINC00967922 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 188007 CCc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 InChI=1S/C23H23BrCl2N4O/c1-2-18-21(23(31)28-29-12-4-3-5-13-29)27-30(20-11-10-17(25)14-19(20)26)22(18)15-6-8-16(24)9-7-15/h6-11,14H,2-5,12-13H2,1H3,(H,28,31) HMXDWDSNPRNUKI-UHFFFAOYSA-N 50171290 5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide::CHEMBL189676::SR 147778 D(2) dopamine receptor Homo sapiens 1000 PDSP Ki 10.1124/jpet.104.067884 10.7270/Q2RR1WTX 15131245 Rinaldi-Carmona, M; Barth, F; Congy, C; Martinez, S; Oustric, D; Pério, A; Poncelet, M; Maruani, J; Arnone, M; Finance, O; Soubrié, P; Le Fur, G Sanofi-Synthelabo Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9849616 104057543 CHEMBL189676 ZINC01549068 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189188 OCCN1CCN(CC1)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2 JSBWGXQXCRYYTG-UHFFFAOYSA-N 50002012 (trans) 2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL1204138::CHEMBL12628::tefludazine D(2) dopamine receptor Homo sapiens 0.7 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4913274 103916365 CHEMBL12628CHEMBL1204138 ZINC22937858 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189189 OCCN1CCN(CC1)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2 JSBWGXQXCRYYTG-UHFFFAOYSA-N 50002012 (trans) 2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL1204138::CHEMBL12628::tefludazine D(2) dopamine receptor Homo sapiens 0.3 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4913274 103916365 CHEMBL12628CHEMBL1204138 ZINC22937858 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189190 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Homo sapiens 21 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189191 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3C(=CCCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3 GFBKORZTTCHDGY-UHFFFAOYSA-N 86187 CAS_22189-31-7::NSC_5454::THIOTHIXENE D(2) dopamine receptor Homo sapiens 0.03 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86187&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941650 136352287 ZINC29747244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189192 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3C(=CCCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3 GFBKORZTTCHDGY-UHFFFAOYSA-N 86187 CAS_22189-31-7::NSC_5454::THIOTHIXENE D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86187&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941650 136352287 ZINC29747244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189193 CCN(CC)CCNC(=O)c1cc(ccc1OC)S(C)(=O)=O InChI=1S/C15H24N2O4S/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18) JTVPZMFULRWINT-UHFFFAOYSA-N 82073 CAS_51012-32-9::NSC_5467::Tiapride D(2) dopamine receptor Homo sapiens 226 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5467 131342647 ZINC01542927 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189194 CCN(CC)CCNC(=O)c1cc(ccc1OC)S(C)(=O)=O InChI=1S/C15H24N2O4S/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18) JTVPZMFULRWINT-UHFFFAOYSA-N 82073 CAS_51012-32-9::NSC_5467::Tiapride D(2) dopamine receptor Homo sapiens 31 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5467 131342647 ZINC01542927 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189195 OC1(CCN(CC1)C(F)CCC(=O)c1ccccc1)c1cccc(c1)C(F)(F)F InChI=1S/C22H23F4NO2/c23-20(10-9-19(28)16-5-2-1-3-6-16)27-13-11-21(29,12-14-27)17-7-4-8-18(15-17)22(24,25)26/h1-8,15,20,29H,9-14H2 ZIRLJRABDORTEO-UHFFFAOYSA-N 81493 CAS_749-13-3::TRIFLUORPERIDOL D(2) dopamine receptor Homo sapiens 0.4 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21514163 131342067 ZINC70463268 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189196 OC1(CCN(CC1)C(F)CCC(=O)c1ccccc1)c1cccc(c1)C(F)(F)F InChI=1S/C22H23F4NO2/c23-20(10-9-19(28)16-5-2-1-3-6-16)27-13-11-21(29,12-14-27)17-7-4-8-18(15-17)22(24,25)26/h1-8,15,20,29H,9-14H2 ZIRLJRABDORTEO-UHFFFAOYSA-N 81493 CAS_749-13-3::TRIFLUORPERIDOL D(2) dopamine receptor Homo sapiens 0.2 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21514163 131342067 ZINC70463268 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189197 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 5.7 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189198 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 3 PDSP Ki 10.1124/jpet.105.092155 10.7270/Q2Z60MNB 16135699 Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR ACADIA Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189356 NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1 InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24) ROFVXGGUISEHAM-UHFFFAOYSA-N 26739 3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate::CHEMBL184238::URB 597::URB-597::URB597::US9187413, 1a (URB597) D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1073/pnas.0509591102 10.7270/Q2F47MQJ 16352709 Gobbi, G; Bambico, FR; Mangieri, R; Bortolato, M; Campolongo, P; Solinas, M; Cassano, T; Morgese, MG; Debonnel, G; Duranti, A; Tontini, A; Tarzia, G; Mor, M; Trezza, V; Goldberg, SR; Cuomo, V; Piomelli, D McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1383884 57298451 CHEMBL184238 4339 ZINC01238258 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189513 CN(C)CC(c1ccc(O)cc1)C1(O)CCCCC1 InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3 KYYIDSXMWOZKMP-UHFFFAOYSA-N 86748 CAS_386750-22-7::Desvenlafaxine::NSC_6918664::O-Desmethylvenlafaxine::US9944618, Compound ID No. 181 D(2) dopamine receptor Homo sapiens >10000 PDSP Ki 10.1124/jpet.106.103382 10.7270/Q2SF2TRS 16675639 Deecher, DC; Beyer, CE; Johnston, G; Bray, J; Shah, S; Abou-Gharbia, M; Andree, TH Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86748&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 29J 4MMC,4MM7 125017 136352797 DB06700 ZINC02525885 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 189575 COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3 SBPRIAGPYFYCRT-UHFFFAOYSA-N 86708 CAS_146714-97-8::CHEMBL31354::CHEMBL514874::CHEMBL537403::NSC_104911::WAY 100,635 D(2) dopamine receptor Homo sapiens 940 PDSP Ki 10.1007/s00213-006-0490-4 10.7270/Q2HX1B8P 16915381 Chemel, BR; Roth, BL; Armbruster, B; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86708&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5684 136352757 CHEMBL537403CHEMBL514874CHEMBL31354 ZINC52541473 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 221887 OC(=O)CNC(=O)c1nc(Cl)c2ccccc2c1O InChI=1S/C12H9ClN2O4/c13-11-7-4-2-1-3-6(7)10(18)9(15-11)12(19)14-5-8(16)17/h1-4,18H,5H2,(H,14,19)(H,16,17) OUQVKRKGTAUJQA-UHFFFAOYSA-N 50193145 2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)acetic acid::CHEMBL426560::Isoquinoline 3::N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE D(2) dopamine receptor Homo sapiens >2.0e+4 7.5 Curated from the literature by BindingDB 10.1021/cb400088q 10.7270/Q29Z93HF 23683440 aid1800084 Chowdhury, R; Candela-Lena, JI; Chan, MC; Greenald, DJ; Yeoh, KK; Tian, YM; McDonough, MA; Tumber, A; Rose, NR; Conejo-Garcia, A; Demetriades, M; Mathavan, S; Kawamura, A; Lee, MK; van Eeden, F; Pugh, CW; Ratcliffe, PJ; Schofield, CJ University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193145&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search UN9 6YW2,4UWD,2HBT,2HBU,5LBC,4CSW,2Y34,2Y33,3HQU,5LAT,4BQX,4NHM,4NJ4,5LBE,5LBF,5LBB,5LB6,4IE6 6914666 104075714 CHEMBL426560 DB08687 ZINC00007670 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 221888 Cc1nc(C(=O)NCC(O)=O)c(O)c2ccccc12 InChI=1S/C13H12N2O4/c1-7-8-4-2-3-5-9(8)12(18)11(15-7)13(19)14-6-10(16)17/h2-5,18H,6H2,1H3,(H,14,19)(H,16,17) AWPFDEKASBPACV-UHFFFAOYSA-N 103842 4HQ derivative 4 D(2) dopamine receptor Homo sapiens >1.00e+5 7.5 Curated from the literature by BindingDB 10.1021/cb400088q 10.7270/Q29Z93HF 23683440 aid1800084 Chowdhury, R; Candela-Lena, JI; Chan, MC; Greenald, DJ; Yeoh, KK; Tian, YM; McDonough, MA; Tumber, A; Rose, NR; Conejo-Garcia, A; Demetriades, M; Mathavan, S; Kawamura, A; Lee, MK; van Eeden, F; Pugh, CW; Ratcliffe, PJ; Schofield, CJ University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11857407 172541656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 221889 OC(=O)CNC(=O)c1nc(Cc2ccccc2)c2ccccc2c1O InChI=1S/C19H16N2O4/c22-16(23)11-20-19(25)17-18(24)14-9-5-4-8-13(14)15(21-17)10-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23) PKMLICBZRGTSJH-UHFFFAOYSA-N 103843 4HQ derivative 6 D(2) dopamine receptor Homo sapiens >1.00e+5 7.5 Curated from the literature by BindingDB 10.1021/cb400088q 10.7270/Q29Z93HF 23683440 aid1800084 Chowdhury, R; Candela-Lena, JI; Chan, MC; Greenald, DJ; Yeoh, KK; Tian, YM; McDonough, MA; Tumber, A; Rose, NR; Conejo-Garcia, A; Demetriades, M; Mathavan, S; Kawamura, A; Lee, MK; van Eeden, F; Pugh, CW; Ratcliffe, PJ; Schofield, CJ University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72699308 172541657 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 221890 OC(=O)CNC(=O)c1nc(CC=C)c2ccccc2c1O InChI=1S/C15H14N2O4/c1-2-5-11-9-6-3-4-7-10(9)14(20)13(17-11)15(21)16-8-12(18)19/h2-4,6-7,20H,1,5,8H2,(H,16,21)(H,18,19) ZAOVMTNYAPSHFW-UHFFFAOYSA-N 103844 4HQ derivative 7 D(2) dopamine receptor Homo sapiens >1.00e+5 7.5 Curated from the literature by BindingDB 10.1021/cb400088q 10.7270/Q29Z93HF 23683440 aid1800084 Chowdhury, R; Candela-Lena, JI; Chan, MC; Greenald, DJ; Yeoh, KK; Tian, YM; McDonough, MA; Tumber, A; Rose, NR; Conejo-Garcia, A; Demetriades, M; Mathavan, S; Kawamura, A; Lee, MK; van Eeden, F; Pugh, CW; Ratcliffe, PJ; Schofield, CJ University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72699309 172541658 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 221891 CCCCCCCc1nc(C(=O)NCC(O)=O)c(O)c2ccccc12 InChI=1S/C19H24N2O4/c1-2-3-4-5-6-11-15-13-9-7-8-10-14(13)18(24)17(21-15)19(25)20-12-16(22)23/h7-10,24H,2-6,11-12H2,1H3,(H,20,25)(H,22,23) VDEUJVUTGALZBR-UHFFFAOYSA-N 103845 4HQ derivative 8 D(2) dopamine receptor Homo sapiens >1.00e+5 7.5 Curated from the literature by BindingDB 10.1021/cb400088q 10.7270/Q29Z93HF 23683440 aid1800084 Chowdhury, R; Candela-Lena, JI; Chan, MC; Greenald, DJ; Yeoh, KK; Tian, YM; McDonough, MA; Tumber, A; Rose, NR; Conejo-Garcia, A; Demetriades, M; Mathavan, S; Kawamura, A; Lee, MK; van Eeden, F; Pugh, CW; Ratcliffe, PJ; Schofield, CJ University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72699310 172541659 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 221892 OC(=O)CNC(=O)c1nc(Cc2ccccc2)c2ccc(Br)cc2c1O InChI=1S/C19H15BrN2O4/c20-12-6-7-13-14(9-12)18(25)17(19(26)21-10-16(23)24)22-15(13)8-11-4-2-1-3-5-11/h1-7,9,25H,8,10H2,(H,21,26)(H,23,24) HULTUDXQDLVDBE-UHFFFAOYSA-N 103846 4HQ derivative 9 D(2) dopamine receptor Homo sapiens >1.00e+5 7.5 Curated from the literature by BindingDB 10.1021/cb400088q 10.7270/Q29Z93HF 23683440 aid1800084 Chowdhury, R; Candela-Lena, JI; Chan, MC; Greenald, DJ; Yeoh, KK; Tian, YM; McDonough, MA; Tumber, A; Rose, NR; Conejo-Garcia, A; Demetriades, M; Mathavan, S; Kawamura, A; Lee, MK; van Eeden, F; Pugh, CW; Ratcliffe, PJ; Schofield, CJ University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72699311 172541660 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224882 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C21H30N4O2/c1-16(26)23-18-4-2-17(3-5-18)7-10-24-11-13-25(14-12-24)21-19-8-15-27-20(19)6-9-22-21/h6,8-9,15,17-18H,2-5,7,10-14H2,1H3,(H,23,26)/t17-,18- NWXLNEMDCWELOX-IYARVYRRSA-N 106412 US8586579, 1 D(2) dopamine receptor Homo sapiens 486 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106412&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768825 174008723 ZINC96177315 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224883 CO[C@@H]1CC[C@@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4occc34)CC2)C1 InChI=1S/C27H40N4O3/c1-33-23-7-4-21(18-23)19-26(32)29-22-5-2-20(3-6-22)9-12-30-13-15-31(16-14-30)27-24-10-17-34-25(24)8-11-28-27/h8,10-11,17,20-23H,2-7,9,12-16,18-19H2,1H3,(H,29,32)/t20-,21-,22-,23-/m1/s1 OEQABNLZLBEHPD-SSGKUCQKSA-N 106413 US8586579, 2 D(2) dopamine receptor Homo sapiens 802 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106413&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768827 174008724 ZINC96177316 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224884 O[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4occc34)CC2)CC1 InChI=1S/C27H40N4O3/c32-23-7-3-21(4-8-23)19-26(33)29-22-5-1-20(2-6-22)10-13-30-14-16-31(17-15-30)27-24-11-18-34-25(24)9-12-28-27/h9,11-12,18,20-23,32H,1-8,10,13-17,19H2,(H,29,33)/t20-,21-,22-,23- JNSGCKSGQOFGBY-KBQPQWKXSA-N 106414 US8586579, 3 D(2) dopamine receptor Homo sapiens 1538 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106414&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768826 174008725 ZINC96177317 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224885 CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C22H32N4O2/c1-2-21(27)24-18-5-3-17(4-6-18)8-11-25-12-14-26(15-13-25)22-19-9-16-28-20(19)7-10-23-22/h7,9-10,16-18H,2-6,8,11-15H2,1H3,(H,24,27)/t17-,18- CXLYWFQWNGCVEG-IYARVYRRSA-N 106415 US8586579, 4 D(2) dopamine receptor Homo sapiens 780 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106415&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768828 174008726 ZINC96177318 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224886 COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C23H34N4O3/c1-29-16-9-22(28)25-19-4-2-18(3-5-19)7-11-26-12-14-27(15-13-26)23-20-8-17-30-21(20)6-10-24-23/h6,8,10,17-19H,2-5,7,9,11-16H2,1H3,(H,25,28)/t18-,19- JSEGPLRTWBZZOJ-WGSAOQKQSA-N 106416 US8586579, 5 D(2) dopamine receptor Homo sapiens 1347 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106416&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769057 174008727 ZINC96177319 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224887 OCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C22H32N4O3/c27-15-7-21(28)24-18-3-1-17(2-4-18)6-10-25-11-13-26(14-12-25)22-19-8-16-29-20(19)5-9-23-22/h5,8-9,16-18,27H,1-4,6-7,10-15H2,(H,24,28)/t17-,18- UOQPMMUMTSDTOB-IYARVYRRSA-N 106417 US8586579, 6 D(2) dopamine receptor Homo sapiens 959 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106417&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769058 174008728 ZINC96177320 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224888 OCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C21H30N4O3/c26-15-20(27)23-17-3-1-16(2-4-17)6-9-24-10-12-25(13-11-24)21-18-7-14-28-19(18)5-8-22-21/h5,7-8,14,16-17,26H,1-4,6,9-13,15H2,(H,23,27)/t16-,17- PNHVOOVVCPJXPA-QAQDUYKDSA-N 106418 US8586579, 7 D(2) dopamine receptor Homo sapiens 1360 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769059 174008729 ZINC96177321 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224889 COCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C22H32N4O3/c1-28-16-21(27)24-18-4-2-17(3-5-18)7-10-25-11-13-26(14-12-25)22-19-8-15-29-20(19)6-9-23-22/h6,8-9,15,17-18H,2-5,7,10-14,16H2,1H3,(H,24,27)/t17-,18- WVCHGRAYLHEGAY-IYARVYRRSA-N 106419 US8586579, 8 D(2) dopamine receptor Homo sapiens 1158 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769060 174008730 ZINC96177322 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224890 CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4occc34)CC2)CC1 InChI=1S/C28H42N4O3/c1-34-24-8-4-22(5-9-24)20-27(33)30-23-6-2-21(3-7-23)11-14-31-15-17-32(18-16-31)28-25-12-19-35-26(25)10-13-29-28/h10,12-13,19,21-24H,2-9,11,14-18,20H2,1H3,(H,30,33)/t21-,22-,23-,24- IXDPGYMHLOZKPR-ZWGSZDQZSA-N 106420 US8586579, 9 D(2) dopamine receptor Homo sapiens 1463 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106420&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769061 174008731 ZINC96177323 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224891 O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C26H38N4O3/c31-25(19-21-7-16-32-17-8-21)28-22-3-1-20(2-4-22)6-11-29-12-14-30(15-13-29)26-23-9-18-33-24(23)5-10-27-26/h5,9-10,18,20-22H,1-4,6-8,11-17,19H2,(H,28,31)/t20-,22- LJEOXWDSLFLRNN-AQYVVDRMSA-N 106421 US8586579, 10 D(2) dopamine receptor Homo sapiens 683 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769062 174008732 ZINC96177324 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224892 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1)C1CCOCC1 InChI=1S/C25H36N4O3/c30-25(20-7-16-31-17-8-20)27-21-3-1-19(2-4-21)6-11-28-12-14-29(15-13-28)24-22-9-18-32-23(22)5-10-26-24/h5,9-10,18-21H,1-4,6-8,11-17H2,(H,27,30)/t19-,21- SQLGEXQBAJPFNZ-XUTJKUGGSA-N 106422 US8586579, 11 D(2) dopamine receptor Homo sapiens 515 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769294 174008733 ZINC96177325 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224893 CCOCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C23H34N4O3/c1-2-29-17-22(28)25-19-5-3-18(4-6-19)8-11-26-12-14-27(15-13-26)23-20-9-16-30-21(20)7-10-24-23/h7,9-10,16,18-19H,2-6,8,11-15,17H2,1H3,(H,25,28)/t18-,19- WRBKFBAHOMAFKJ-WGSAOQKQSA-N 106423 US8586579, 12 D(2) dopamine receptor Homo sapiens 996 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106423&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769295 174008734 ZINC96177326 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224894 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1)C1CC1 InChI=1S/C23H32N4O2/c28-23(18-3-4-18)25-19-5-1-17(2-6-19)8-11-26-12-14-27(15-13-26)22-20-9-16-29-21(20)7-10-24-22/h7,9-10,16-19H,1-6,8,11-15H2,(H,25,28)/t17-,19- SVONVXKDHRPGFI-UAPYVXQJSA-N 106424 US8586579, 13 D(2) dopamine receptor Homo sapiens 261 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106424&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769296 174008735 ZINC96177327 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224895 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C20H30N4O3S/c1-28(25,26)22-17-4-2-16(3-5-17)7-10-23-11-13-24(14-12-23)20-18-8-15-27-19(18)6-9-21-20/h6,8-9,15-17,22H,2-5,7,10-14H2,1H3/t16-,17- XGWUEDFPOSFGBM-QAQDUYKDSA-N 106425 US8586579, 14 D(2) dopamine receptor Homo sapiens 866 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106425&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769297 174008736 ZINC96177328 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224896 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1 InChI=1S/C21H30N4OS/c1-16(26)23-18-4-2-17(3-5-18)7-10-24-11-13-25(14-12-24)21-19-8-15-27-20(19)6-9-22-21/h6,8-9,15,17-18H,2-5,7,10-14H2,1H3,(H,23,26)/t17-,18- DKJHWZSZJVWAQC-IYARVYRRSA-N 106426 US8586579, 15 D(2) dopamine receptor Homo sapiens 119 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106426&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769298 174008737 ZINC96177329 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224897 CCS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C21H32N4O3S/c1-2-29(26,27)23-18-5-3-17(4-6-18)8-11-24-12-14-25(15-13-24)21-19-9-16-28-20(19)7-10-22-21/h7,9-10,16-18,23H,2-6,8,11-15H2,1H3/t17-,18- KNWOHCMLVYZTJW-IYARVYRRSA-N 106427 US8586579, 16 D(2) dopamine receptor Homo sapiens 780 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770167 174008738 ZINC96177330 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224898 CN(C)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1 InChI=1S/C21H33N5O3S/c1-24(2)30(27,28)23-18-5-3-17(4-6-18)8-11-25-12-14-26(15-13-25)21-19-9-16-29-20(19)7-10-22-21/h7,9-10,16-18,23H,3-6,8,11-15H2,1-2H3/t17-,18- UJBLYPURSDWDKF-IYARVYRRSA-N 106428 US8586579, 17 D(2) dopamine receptor Homo sapiens 539 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770168 174008739 ZINC96177331 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224899 CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1 InChI=1S/C22H32N4OS/c1-2-21(27)24-18-5-3-17(4-6-18)8-11-25-12-14-26(15-13-25)22-19-9-16-28-20(19)7-10-23-22/h7,9-10,16-18H,2-6,8,11-15H2,1H3,(H,24,27)/t17-,18- TYZKGCIDJUPIPC-IYARVYRRSA-N 106429 US8586579, 18 D(2) dopamine receptor Homo sapiens 163 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769299 174008740 ZINC96177332 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224900 COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1 InChI=1S/C23H34N4O2S/c1-29-16-8-22(28)25-19-4-2-18(3-5-19)7-11-26-12-14-27(15-13-26)23-20-9-17-30-21(20)6-10-24-23/h6,9-10,17-19H,2-5,7-8,11-16H2,1H3,(H,25,28)/t18-,19- PXCHOWMQGZACON-WGSAOQKQSA-N 106430 US8586579, 19 D(2) dopamine receptor Homo sapiens 305 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769521 174008741 ZINC96177333 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224901 CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4sccc34)CC2)CC1 InChI=1S/C28H42N4O2S/c1-34-24-8-4-22(5-9-24)20-27(33)30-23-6-2-21(3-7-23)11-14-31-15-17-32(18-16-31)28-25-12-19-35-26(25)10-13-29-28/h10,12-13,19,21-24H,2-9,11,14-18,20H2,1H3,(H,30,33)/t21-,22-,23-,24- GSZBDACNBVTFKJ-ZWGSZDQZSA-N 106431 US8586579, 20 D(2) dopamine receptor Homo sapiens 302 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769522 174008742 ZINC96177334 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224902 CO[C@@H]1CC[C@@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4sccc34)CC2)C1 InChI=1S/C27H40N4O2S/c1-33-23-7-4-21(18-23)19-26(32)29-22-5-2-20(3-6-22)9-12-30-13-15-31(16-14-30)27-24-10-17-34-25(24)8-11-28-27/h8,10-11,17,20-23H,2-7,9,12-16,18-19H2,1H3,(H,29,32)/t20-,21-,22-,23-/m1/s1 ZJADORDBVJWZKV-SSGKUCQKSA-N 106432 US8586579, 21 D(2) dopamine receptor Homo sapiens 271 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769523 174008743 ZINC96177335 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224903 COCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1 InChI=1S/C22H32N4O2S/c1-28-16-21(27)24-18-4-2-17(3-5-18)7-10-25-11-13-26(14-12-25)22-19-8-15-29-20(19)6-9-23-22/h6,8-9,15,17-18H,2-5,7,10-14,16H2,1H3,(H,24,27)/t17-,18- CCIIACYBEVIIIN-IYARVYRRSA-N 106433 US8586579, 22 D(2) dopamine receptor Homo sapiens 220 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769524 174008744 ZINC96177336 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224904 O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1 InChI=1S/C26H38N4O2S/c31-25(19-21-7-16-32-17-8-21)28-22-3-1-20(2-4-22)6-11-29-12-14-30(15-13-29)26-23-9-18-33-24(23)5-10-27-26/h5,9-10,18,20-22H,1-4,6-8,11-17,19H2,(H,28,31)/t20-,22- OFWNLCWKTRJZBM-AQYVVDRMSA-N 106434 US8586579, 23 D(2) dopamine receptor Homo sapiens 144 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769525 174008745 ZINC96177337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224905 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1)C1CCOCC1 InChI=1S/C25H36N4O2S/c30-25(20-7-16-31-17-8-20)27-21-3-1-19(2-4-21)6-11-28-12-14-29(15-13-28)24-22-9-18-32-23(22)5-10-26-24/h5,9-10,18-21H,1-4,6-8,11-17H2,(H,27,30)/t19-,21- ZERNPQRYLXBKKZ-XUTJKUGGSA-N 106435 US8586579, 24 D(2) dopamine receptor Homo sapiens 992 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769526 174008746 ZINC96177338 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224906 CO[C@@H]1CC[C@@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4sccc34)CC2)C1 InChI=1S/C27H40N4O2S/c1-33-23-7-4-21(18-23)19-26(32)29-22-5-2-20(3-6-22)9-12-30-13-15-31(16-14-30)27-24-10-17-34-25(24)8-11-28-27/h8,10-11,17,20-23H,2-7,9,12-16,18-19H2,1H3,(H,29,32)/t20-,21-,22-,23-/m1/s1 ZJADORDBVJWZKV-SSGKUCQKSA-N 106436 US8586579, 25 D(2) dopamine receptor Homo sapiens 234 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769523 174008747 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224907 CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4sccc34)CC2)C1 InChI=1S/C27H40N4O2S/c1-33-23-7-4-21(18-23)19-26(32)29-22-5-2-20(3-6-22)9-12-30-13-15-31(16-14-30)27-24-10-17-34-25(24)8-11-28-27/h8,10-11,17,20-23H,2-7,9,12-16,18-19H2,1H3,(H,29,32)/t20-,21-,22-,23-/m0/s1 ZJADORDBVJWZKV-MLCQCVOFSA-N 106437 US8586579, 26 D(2) dopamine receptor Homo sapiens 246 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125949 174008748 ZINC96177339 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224908 OCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1 InChI=1S/C21H30N4O2S/c26-15-20(27)23-17-3-1-16(2-4-17)6-9-24-10-12-25(13-11-24)21-18-7-14-28-19(18)5-8-22-21/h5,7-8,14,16-17,26H,1-4,6,9-13,15H2,(H,23,27)/t16-,17- OYIQKTRWSDEITE-QAQDUYKDSA-N 106438 US8586579, 27 D(2) dopamine receptor Homo sapiens 218 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768043 174008749 ZINC96177340 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224909 O[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4sccc34)CC2)CC1 InChI=1S/C27H40N4O2S/c32-23-7-3-21(4-8-23)19-26(33)29-22-5-1-20(2-6-22)10-13-30-14-16-31(17-15-30)27-24-11-18-34-25(24)9-12-28-27/h9,11-12,18,20-23,32H,1-8,10,13-17,19H2,(H,29,33)/t20-,21-,22-,23- WKCSANGLEHNNKN-KBQPQWKXSA-N 106439 US8586579, 28 D(2) dopamine receptor Homo sapiens 392 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768824 174008750 ZINC96177341 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224910 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3occc23)CC1)c1ccnc2ccccc12 InChI=1S/C29H33N5O2/c35-29(24-9-13-30-26-4-2-1-3-23(24)26)32-22-7-5-21(6-8-22)11-15-33-16-18-34(19-17-33)28-25-12-20-36-27(25)10-14-31-28/h1-4,9-10,12-14,20-22H,5-8,11,15-19H2,(H,32,35)/t21-,22- IQGWEXBXERIPCR-HZCBDIJESA-N 106440 US8586579, 29 D(2) dopamine receptor Homo sapiens 461 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769738 174008751 ZINC96177342 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224911 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1 InChI=1S/C20H30N4O2S2/c1-28(25,26)22-17-4-2-16(3-5-17)7-10-23-11-13-24(14-12-23)20-18-8-15-27-19(18)6-9-21-20/h6,8-9,15-17,22H,2-5,7,10-14H2,1H3/t16-,17- BUNARIUEVNWERA-QAQDUYKDSA-N 106441 US8586579, 30 D(2) dopamine receptor Homo sapiens 265 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769739 174008752 ZINC96177343 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224912 CCS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3sccc23)CC1 InChI=1S/C21H32N4O2S2/c1-2-29(26,27)23-18-5-3-17(4-6-18)8-11-24-12-14-25(15-13-24)21-19-9-16-28-20(19)7-10-22-21/h7,9-10,16-18,23H,2-6,8,11-15H2,1H3/t17-,18- RRYHHCNEVZLSCS-IYARVYRRSA-N 106442 US8586579, 31 D(2) dopamine receptor Homo sapiens 217 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769740 174008753 ZINC96177344 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224913 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C21H32N4O2/c1-16(26)23-18-4-2-17(3-5-18)7-10-24-11-13-25(14-12-24)21-19-8-15-27-20(19)6-9-22-21/h6,9,17-18H,2-5,7-8,10-15H2,1H3,(H,23,26)/t17-,18- SQRMELSMCDEARL-IYARVYRRSA-N 106443 US8586579, 32 D(2) dopamine receptor Homo sapiens 770.1 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769741 174008754 ZINC96177345 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224914 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)C1CCOCC1 InChI=1S/C25H38N4O3/c30-25(20-7-16-31-17-8-20)27-21-3-1-19(2-4-21)6-11-28-12-14-29(15-13-28)24-22-9-18-32-23(22)5-10-26-24/h5,10,19-21H,1-4,6-9,11-18H2,(H,27,30)/t19-,21- NNECCFXSSVWBTA-XUTJKUGGSA-N 106444 US8586579, 33 D(2) dopamine receptor Homo sapiens 503.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769742 174008755 ZINC96177346 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224915 O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C26H40N4O3/c31-25(19-21-7-16-32-17-8-21)28-22-3-1-20(2-4-22)6-11-29-12-14-30(15-13-29)26-23-9-18-33-24(23)5-10-27-26/h5,10,20-22H,1-4,6-9,11-19H2,(H,28,31)/t20-,22- WBVLCBQDISBZLH-AQYVVDRMSA-N 106445 US8586579, 61 D(2) dopamine receptor Homo sapiens 869 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769743 174008756 ZINC96177347 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224916 COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H36N4O3/c1-29-16-9-22(28)25-19-4-2-18(3-5-19)7-11-26-12-14-27(15-13-26)23-20-8-17-30-21(20)6-10-24-23/h6,10,18-19H,2-5,7-9,11-17H2,1H3,(H,25,28)/t18-,19- RSOWGGVCBJACCG-WGSAOQKQSA-N 106446 US8586579, 62 D(2) dopamine receptor Homo sapiens 1488 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769948 174008757 ZINC96177348 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224917 CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C22H34N4O2/c1-2-21(27)24-18-5-3-17(4-6-18)8-11-25-12-14-26(15-13-25)22-19-9-16-28-20(19)7-10-23-22/h7,10,17-18H,2-6,8-9,11-16H2,1H3,(H,24,27)/t17-,18- HHRGFYRLYOYIFM-IYARVYRRSA-N 106447 US8586579, 36 D(2) dopamine receptor Homo sapiens 812.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769949 174008758 ZINC96177349 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224918 O=C(CC1COCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H38N4O4/c30-24(17-21-18-31-15-16-32-21)27-20-3-1-19(2-4-20)6-9-28-10-12-29(13-11-28)25-22-7-14-33-23(22)5-8-26-25/h5,8,19-21H,1-4,6-7,9-18H2,(H,27,30)/t19-,20-,21? YGCYKAKZEZYUMC-YGQOYYDZSA-N 106448 US8586579, 37 D(2) dopamine receptor Homo sapiens 1471.4 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769951 174008759 ZINC96177351 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224919 COCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C22H34N4O3/c1-28-16-21(27)24-18-4-2-17(3-5-18)7-10-25-11-13-26(14-12-25)22-19-8-15-29-20(19)6-9-23-22/h6,9,17-18H,2-5,7-8,10-16H2,1H3,(H,24,27)/t17-,18- PZYRQKWSXFGUED-IYARVYRRSA-N 106449 US8586579, 38 D(2) dopamine receptor Homo sapiens 1545.4 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769950 174008760 ZINC96177352 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224920 CS(=O)(=O)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C22H34N4O4S/c1-31(28,29)16-21(27)24-18-4-2-17(3-5-18)7-10-25-11-13-26(14-12-25)22-19-8-15-30-20(19)6-9-23-22/h6,9,17-18H,2-5,7-8,10-16H2,1H3,(H,24,27)/t17-,18- ZDFGDUYZGMNXLU-IYARVYRRSA-N 106450 US8586579, 39 D(2) dopamine receptor Homo sapiens 1018.3 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769952 174008761 ZINC96177353 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224921 OCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C21H32N4O3/c26-15-20(27)23-17-3-1-16(2-4-17)6-9-24-10-12-25(13-11-24)21-18-7-14-28-19(18)5-8-22-21/h5,8,16-17,26H,1-4,6-7,9-15H2,(H,23,27)/t16-,17- HUEMJHLBWFDXTF-QAQDUYKDSA-N 106451 US8586579, 40 D(2) dopamine receptor Homo sapiens 1568 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769953 174008762 ZINC96177354 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224922 OCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C22H34N4O3/c27-15-7-21(28)24-18-3-1-17(2-4-18)6-10-25-11-13-26(14-12-25)22-19-8-16-29-20(19)5-9-23-22/h5,9,17-18,27H,1-4,6-8,10-16H2,(H,24,28)/t17-,18- YMPBYYINMWNUQV-IYARVYRRSA-N 106452 US8586579, 41 D(2) dopamine receptor Homo sapiens 733.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106452&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770164 174008763 ZINC96177355 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224923 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)C1CCOC1 InChI=1S/C24H36N4O3/c29-24(19-7-15-30-17-19)26-20-3-1-18(2-4-20)6-10-27-11-13-28(14-12-27)23-21-8-16-31-22(21)5-9-25-23/h5,9,18-20H,1-4,6-8,10-17H2,(H,26,29)/t18-,19?,20- YNWOVSGFFVVSBU-UQTQIZBZSA-N 106453 US8586579, 42 D(2) dopamine receptor Homo sapiens 609.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770165 174008764 ZINC96177357 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224924 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)C1CCCO1 InChI=1S/C24H36N4O3/c29-24(22-2-1-16-30-22)26-19-5-3-18(4-6-19)8-11-27-12-14-28(15-13-27)23-20-9-17-31-21(20)7-10-25-23/h7,10,18-19,22H,1-6,8-9,11-17H2,(H,26,29)/t18-,19-,22? HZQQJAKATKCPDP-DDDLIOIYSA-N 106454 US8586579, 43 D(2) dopamine receptor Homo sapiens 1044 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770166 174008765 ZINC96177359 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224925 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccccc1 InChI=1S/C26H34N4O2/c31-26(21-4-2-1-3-5-21)28-22-8-6-20(7-9-22)11-14-29-15-17-30(18-16-29)25-23-12-19-32-24(23)10-13-27-25/h1-5,10,13,20,22H,6-9,11-12,14-19H2,(H,28,31)/t20-,22- HAABSCYMCZRVTB-AQYVVDRMSA-N 106455 US8586579, 44 D(2) dopamine receptor Homo sapiens 481.2 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770169 174008766 ZINC96177360 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224926 Fc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C26H33FN4O2/c27-21-5-3-20(4-6-21)26(32)29-22-7-1-19(2-8-22)10-13-30-14-16-31(17-15-30)25-23-11-18-33-24(23)9-12-28-25/h3-6,9,12,19,22H,1-2,7-8,10-11,13-18H2,(H,29,32)/t19-,22- HQAMJNKOXUQUKS-XYWHTSSQSA-N 106456 US8586579, 45 D(2) dopamine receptor Homo sapiens 341.9 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770380 174008767 ZINC96177361 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224927 Clc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C26H33ClN4O2/c27-21-5-3-20(4-6-21)26(32)29-22-7-1-19(2-8-22)10-13-30-14-16-31(17-15-30)25-23-11-18-33-24(23)9-12-28-25/h3-6,9,12,19,22H,1-2,7-8,10-11,13-18H2,(H,29,32)/t19-,22- HMAKCCQMRGCRHO-XYWHTSSQSA-N 106457 US8586579, 73 D(2) dopamine receptor Homo sapiens 289.2 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770381 174008768 ZINC96177362 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224928 FC(F)(F)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C27H33F3N4O2/c28-27(29,30)21-5-3-20(4-6-21)26(35)32-22-7-1-19(2-8-22)10-13-33-14-16-34(17-15-33)25-23-11-18-36-24(23)9-12-31-25/h3-6,9,12,19,22H,1-2,7-8,10-11,13-18H2,(H,32,35)/t19-,22- JVTXPXRMOCVEDH-XYWHTSSQSA-N 106458 US8586579, 74 D(2) dopamine receptor Homo sapiens 871.2 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770382 174008769 ZINC96177363 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224929 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C20H32N4O3S/c1-28(25,26)22-17-4-2-16(3-5-17)7-10-23-11-13-24(14-12-23)20-18-8-15-27-19(18)6-9-21-20/h6,9,16-17,22H,2-5,7-8,10-15H2,1H3/t16-,17- ILSVAZDAOVUDJJ-QAQDUYKDSA-N 106459 US8586579, 75 D(2) dopamine receptor Homo sapiens 1269.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770383 174008770 ZINC96177364 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224930 CCS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C21H34N4O3S/c1-2-29(26,27)23-18-5-3-17(4-6-18)8-11-24-12-14-25(15-13-24)21-19-9-16-28-20(19)7-10-22-21/h7,10,17-18,23H,2-6,8-9,11-16H2,1H3/t17-,18- HFJVMFBCUWJLFO-IYARVYRRSA-N 106460 US8586579, 76 D(2) dopamine receptor Homo sapiens 1093.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770384 174008771 ZINC96177365 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224931 Fc1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H33FN4O3S/c26-20-3-7-22(8-4-20)34(31,32)28-21-5-1-19(2-6-21)10-13-29-14-16-30(17-15-29)25-23-11-18-33-24(23)9-12-27-25/h3-4,7-9,12,19,21,28H,1-2,5-6,10-11,13-18H2/t19-,21- OXMLHENURKVGGZ-XUTJKUGGSA-N 106461 US8586579, 50 D(2) dopamine receptor Homo sapiens 240 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106461&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770385 174008772 ZINC96177366 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224932 O=C(CC1CC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H36N4O2/c29-23(17-19-1-2-19)26-20-5-3-18(4-6-20)8-11-27-12-14-28(15-13-27)24-21-9-16-30-22(21)7-10-25-24/h7,10,18-20H,1-6,8-9,11-17H2,(H,26,29)/t18-,20- XPKWZBRQMHEAAX-KESTWPANSA-N 106462 US8586579, 51 D(2) dopamine receptor Homo sapiens 586.8 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125786 174008773 ZINC96177367 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224933 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)C1CCC1 InChI=1S/C24H36N4O2/c29-24(19-2-1-3-19)26-20-6-4-18(5-7-20)9-12-27-13-15-28(16-14-27)23-21-10-17-30-22(21)8-11-25-23/h8,11,18-20H,1-7,9-10,12-17H2,(H,26,29)/t18-,20- IUHXMQOKDMHFCT-KESTWPANSA-N 106463 US8586579, 52 D(2) dopamine receptor Homo sapiens 555 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770598 174008774 ZINC96177368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224934 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)C1CCCOC1 InChI=1S/C25H38N4O3/c30-25(20-2-1-16-31-18-20)27-21-5-3-19(4-6-21)8-11-28-12-14-29(15-13-28)24-22-9-17-32-23(22)7-10-26-24/h7,10,19-21H,1-6,8-9,11-18H2,(H,27,30)/t19-,20?,21- RBGONAOLWTWGIH-HBCBNPTOSA-N 106464 US8586579, 53 D(2) dopamine receptor Homo sapiens 766.8 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770599 174008775 ZINC96177370 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224935 C[C@]1(O)CC[C@@H](CC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C27H42N4O3/c1-27(33)11-6-21(7-12-27)26(32)29-22-4-2-20(3-5-22)9-14-30-15-17-31(18-16-30)25-23-10-19-34-24(23)8-13-28-25/h8,13,20-22,33H,2-7,9-12,14-19H2,1H3,(H,29,32)/t20-,21-,22-,27- XLIXPJRYIUCZIQ-IYQCHBLZSA-N 106465 US8586579, 81 D(2) dopamine receptor Homo sapiens 506.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125777 174008776 ZINC96177371 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224936 C[C@@]1(O)CC[C@@H](CC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C27H42N4O3/c1-27(33)11-6-21(7-12-27)26(32)29-22-4-2-20(3-5-22)9-14-30-15-17-31(18-16-30)25-23-10-19-34-24(23)8-13-28-25/h8,13,20-22,33H,2-7,9-12,14-19H2,1H3,(H,29,32)/t20-,21-,22-,27+ XLIXPJRYIUCZIQ-HUULMPCJSA-N 106466 US8586579, 55 D(2) dopamine receptor Homo sapiens 475 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125777 174008777 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224937 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(cc1)N1CCCCC1 InChI=1S/C31H43N5O2/c37-31(25-6-10-27(11-7-25)35-16-2-1-3-17-35)33-26-8-4-24(5-9-26)13-18-34-19-21-36(22-20-34)30-28-14-23-38-29(28)12-15-32-30/h6-7,10-12,15,24,26H,1-5,8-9,13-14,16-23H2,(H,33,37)/t24-,26- UBLOWVVYFMMWMS-YOCNBXQISA-N 106467 US8586579, 83 D(2) dopamine receptor Homo sapiens 5340 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770600 174008778 ZINC96177372 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224938 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(cc1)N1CCOCC1 InChI=1S/C30H41N5O3/c36-30(24-3-7-26(8-4-24)34-18-21-37-22-19-34)32-25-5-1-23(2-6-25)10-13-33-14-16-35(17-15-33)29-27-11-20-38-28(27)9-12-31-29/h3-4,7-9,12,23,25H,1-2,5-6,10-11,13-22H2,(H,32,36)/t23-,25- WVPMAZJVALETCI-ALOJWSFFSA-N 106468 US8586579, 57 D(2) dopamine receptor Homo sapiens 867.1 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770601 174008779 ZINC96177373 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224939 OC1(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H34N4O3/c28-22(23(29)8-9-23)25-18-3-1-17(2-4-18)6-11-26-12-14-27(15-13-26)21-19-7-16-30-20(19)5-10-24-21/h5,10,17-18,29H,1-4,6-9,11-16H2,(H,25,28)/t17-,18- CKAFITNCAHORFQ-IYARVYRRSA-N 106469 US8586579, 58 D(2) dopamine receptor Homo sapiens 592.9 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125810 174008780 ZINC96177374 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224940 O=C(CC#N)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C22H31N5O2/c23-9-5-21(28)25-18-3-1-17(2-4-18)7-11-26-12-14-27(15-13-26)22-19-8-16-29-20(19)6-10-24-22/h6,10,17-18H,1-5,7-8,11-16H2,(H,25,28)/t17-,18- AZQFGKSDCVQAHH-IYARVYRRSA-N 106470 US8586579, 59 D(2) dopamine receptor Homo sapiens 702.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770602 174008781 ZINC96177375 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224941 FC(F)(F)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C22H31F3N4O2/c23-22(24,25)15-20(30)27-17-3-1-16(2-4-17)6-9-28-10-12-29(13-11-28)21-18-7-14-31-19(18)5-8-26-21/h5,8,16-17H,1-4,6-7,9-15H2,(H,27,30)/t16-,17- KAEYIPLTXHGZRS-QAQDUYKDSA-N 106471 US8586579, 60 D(2) dopamine receptor Homo sapiens 687.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770825 174008782 ZINC96177376 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224942 O=C(C[C@@H]1COCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H38N4O4/c30-24(17-21-18-31-15-16-32-21)27-20-3-1-19(2-4-20)6-9-28-10-12-29(13-11-28)25-22-7-14-33-23(22)5-8-26-25/h5,8,19-21H,1-4,6-7,9-18H2,(H,27,30)/t19-,20-,21-/m1/s1 YGCYKAKZEZYUMC-NJDAHSKKSA-N 106472 US8586579, 61 D(2) dopamine receptor Homo sapiens 1124 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770826 174008783 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224943 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccnc2ccccc12 InChI=1S/C29H35N5O2/c35-29(24-9-13-30-26-4-2-1-3-23(24)26)32-22-7-5-21(6-8-22)11-15-33-16-18-34(19-17-33)28-25-12-20-36-27(25)10-14-31-28/h1-4,9-10,13-14,21-22H,5-8,11-12,15-20H2,(H,32,35)/t21-,22- MVNMMDGTQIXAJK-HZCBDIJESA-N 106473 US8586579, 62 D(2) dopamine receptor Homo sapiens 547.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770827 174008784 ZINC96177377 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224944 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)C1CC1 InChI=1S/C23H34N4O2/c28-23(18-3-4-18)25-19-5-1-17(2-6-19)8-11-26-12-14-27(15-13-26)22-20-9-16-29-21(20)7-10-24-22/h7,10,17-19H,1-6,8-9,11-16H2,(H,25,28)/t17-,19- OUMNETVFYOWILO-UAPYVXQJSA-N 106474 US8586579, 63 D(2) dopamine receptor Homo sapiens 485.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770828 174008785 ZINC96177378 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224945 O=C(CC1CCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H38N4O3/c30-24(18-21-2-1-16-31-21)27-20-5-3-19(4-6-20)8-11-28-12-14-29(15-13-28)25-22-9-17-32-23(22)7-10-26-25/h7,10,19-21H,1-6,8-9,11-18H2,(H,27,30)/t19-,20-,21? SAWRNBNIFPXPCC-YGQOYYDZSA-N 106475 US8586579, 91 D(2) dopamine receptor Homo sapiens 1262.8 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770829 174008786 ZINC96177380 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224946 CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4OCCc34)CC2)CC1 InChI=1S/C28H44N4O3/c1-34-24-8-4-22(5-9-24)20-27(33)30-23-6-2-21(3-7-23)11-14-31-15-17-32(18-16-31)28-25-12-19-35-26(25)10-13-29-28/h10,13,21-24H,2-9,11-12,14-20H2,1H3,(H,30,33)/t21-,22-,23-,24- JCPOEWYYYWHNCO-ZWGSZDQZSA-N 106476 US8586579, 92 D(2) dopamine receptor Homo sapiens 2451.9 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54770830 174008787 ZINC96177381 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224947 CN(C)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C21H35N5O3S/c1-24(2)30(27,28)23-18-5-3-17(4-6-18)8-11-25-12-14-26(15-13-25)21-19-9-16-29-20(19)7-10-22-21/h7,10,17-18,23H,3-6,8-9,11-16H2,1-2H3/t17-,18- CKOUWIPOSAPIGS-IYARVYRRSA-N 106477 US8586579, 66 D(2) dopamine receptor Homo sapiens 781.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106477&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125849 174008788 ZINC96177382 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224948 O=C(C[C@H]1COCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H38N4O4/c30-24(17-21-18-31-15-16-32-21)27-20-3-1-19(2-4-20)6-9-28-10-12-29(13-11-28)25-22-7-14-33-23(22)5-8-26-25/h5,8,19-21H,1-4,6-7,9-18H2,(H,27,30)/t19-,20-,21-/m0/s1 YGCYKAKZEZYUMC-ACRUOGEOSA-N 106478 US8586579, 67 D(2) dopamine receptor Homo sapiens 1461 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106478&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771057 174008789 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224949 O=C(C[C@H]1CCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H38N4O3/c30-24(18-21-2-1-16-31-21)27-20-5-3-19(4-6-20)8-11-28-12-14-29(15-13-28)25-22-9-17-32-23(22)7-10-26-25/h7,10,19-21H,1-6,8-9,11-18H2,(H,27,30)/t19-,20-,21-/m1/s1 SAWRNBNIFPXPCC-NJDAHSKKSA-N 106479 US8586579, 95 D(2) dopamine receptor Homo sapiens 914.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771058 174008790 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224950 O=C(C[C@@H]1CCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H38N4O3/c30-24(18-21-2-1-16-31-21)27-20-5-3-19(4-6-20)8-11-28-12-14-29(15-13-28)25-22-9-17-32-23(22)7-10-26-25/h7,10,19-21H,1-6,8-9,11-18H2,(H,27,30)/t19-,20-,21-/m0/s1 SAWRNBNIFPXPCC-ACRUOGEOSA-N 106480 US8586579, 96 D(2) dopamine receptor Homo sapiens 857.9 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771059 174008791 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224951 CC(C)(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H38N4O2/c1-24(2,3)23(29)26-19-6-4-18(5-7-19)9-12-27-13-15-28(16-14-27)22-20-10-17-30-21(20)8-11-25-22/h8,11,18-19H,4-7,9-10,12-17H2,1-3H3,(H,26,29)/t18-,19- IHNAEAHWHZVEJK-WGSAOQKQSA-N 106481 US8586579, 70 D(2) dopamine receptor Homo sapiens 523.9 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106481&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771060 174008792 ZINC96177383 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224952 CC(C)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H38N4O2/c1-18(2)17-23(29)26-20-5-3-19(4-6-20)8-11-27-12-14-28(15-13-27)24-21-9-16-30-22(21)7-10-25-24/h7,10,18-20H,3-6,8-9,11-17H2,1-2H3,(H,26,29)/t19-,20- FORAQSMKEXXBJZ-MXVIHJGJSA-N 106482 US8586579, 71 D(2) dopamine receptor Homo sapiens 654.8 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106482&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771061 174008793 ZINC96177384 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224953 CC(C)(C)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H40N4O2/c1-25(2,3)18-23(30)27-20-6-4-19(5-7-20)9-12-28-13-15-29(16-14-28)24-21-10-17-31-22(21)8-11-26-24/h8,11,19-20H,4-7,9-10,12-18H2,1-3H3,(H,27,30)/t19-,20- DQVWGUUNHWMPMS-MXVIHJGJSA-N 106483 US8586579, 99 D(2) dopamine receptor Homo sapiens 444.2 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771062 174008794 ZINC96177385 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224954 O=C(CC1CCC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H38N4O2/c30-24(18-20-2-1-3-20)27-21-6-4-19(5-7-21)9-12-28-13-15-29(16-14-28)25-22-10-17-31-23(22)8-11-26-25/h8,11,19-21H,1-7,9-10,12-18H2,(H,27,30)/t19-,21- HRGLDIJXNKMLQF-XUTJKUGGSA-N 106484 US8586579, 73 D(2) dopamine receptor Homo sapiens 602.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771291 174008795 ZINC96177386 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224955 FC1(F)CC1C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H32F2N4O2/c24-23(25)15-19(23)22(30)27-17-3-1-16(2-4-17)6-9-28-10-12-29(13-11-28)21-18-7-14-31-20(18)5-8-26-21/h5,8,16-17,19H,1-4,6-7,9-15H2,(H,27,30)/t16-,17-,19? YFHWGBZGWDWNRV-JHNFVTJISA-N 106485 US8586579, 101 D(2) dopamine receptor Homo sapiens 438.3 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106485&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771292 174008796 ZINC96177388 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224956 CC(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H36N4O2/c1-17(2)23(28)25-19-5-3-18(4-6-19)8-11-26-12-14-27(15-13-26)22-20-9-16-29-21(20)7-10-24-22/h7,10,17-19H,3-6,8-9,11-16H2,1-2H3,(H,25,28)/t18-,19- HGDNRYBOAYQHNG-WGSAOQKQSA-N 106486 US8586579, 75 D(2) dopamine receptor Homo sapiens 705.1 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771293 174008797 ZINC96177389 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224957 CCC(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H38N4O2/c1-3-18(2)24(29)26-20-6-4-19(5-7-20)9-12-27-13-15-28(16-14-27)23-21-10-17-30-22(21)8-11-25-23/h8,11,18-20H,3-7,9-10,12-17H2,1-2H3,(H,26,29)/t18?,19-,20- JPVBGGFMPCPVDU-JUUMZCOKSA-N 106487 US8586579, 103 D(2) dopamine receptor Homo sapiens 709.4 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106487&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771294 174008798 ZINC96177391 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224958 O=C(CC1COC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H36N4O3/c29-23(15-19-16-30-17-19)26-20-3-1-18(2-4-20)6-9-27-10-12-28(13-11-27)24-21-7-14-31-22(21)5-8-25-24/h5,8,18-20H,1-4,6-7,9-17H2,(H,26,29)/t18-,20- KPWFNAZMRFBRMI-KESTWPANSA-N 106488 US8586579, 77 D(2) dopamine receptor Homo sapiens 754.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771295 174008799 ZINC96177392 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224959 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C22H35N5O2/c1-25(2)22(28)24-18-5-3-17(4-6-18)8-11-26-12-14-27(15-13-26)21-19-9-16-29-20(19)7-10-23-21/h7,10,17-18H,3-6,8-9,11-16H2,1-2H3,(H,24,28)/t17-,18- UVEHFXJWIQCNDD-IYARVYRRSA-N 106489 US8586579, 105 D(2) dopamine receptor Homo sapiens 322.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125778 174008800 ZINC96177393 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224960 FC(F)(F)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C21H29F3N4O2/c22-21(23,24)20(29)26-16-3-1-15(2-4-16)6-9-27-10-12-28(13-11-27)19-17-7-14-30-18(17)5-8-25-19/h5,8,15-16H,1-4,6-7,9-14H2,(H,26,29)/t15-,16- SUGHICCAJLONJR-WKILWMFISA-N 106490 US8586579, 106 D(2) dopamine receptor Homo sapiens 773.3 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106490&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86660552 174008801 ZINC96177394 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224961 CC(C)=CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H36N4O2/c1-18(2)17-23(29)26-20-5-3-19(4-6-20)8-11-27-12-14-28(15-13-27)24-21-9-16-30-22(21)7-10-25-24/h7,10,17,19-20H,3-6,8-9,11-16H2,1-2H3,(H,26,29)/t19-,20- NBKJTOGTVMGTOS-MXVIHJGJSA-N 106491 US8586579, 107 D(2) dopamine receptor Homo sapiens 198.4 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125807 174008802 ZINC96177395 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224962 C\C=C\CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H36N4O2/c1-2-3-4-23(29)26-20-7-5-19(6-8-20)10-13-27-14-16-28(17-15-27)24-21-11-18-30-22(21)9-12-25-24/h2-3,9,12,19-20H,4-8,10-11,13-18H2,1H3,(H,26,29)/b3-2+/t19-,20- KZWUXBIYAIXWII-MRGVAMFXSA-N 106492 US8586579, 108 D(2) dopamine receptor Homo sapiens 945.4 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125826 174008803 ZINC96177396 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224963 CC#CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H32N4O2/c1-2-3-22(28)25-19-6-4-18(5-7-19)9-12-26-13-15-27(16-14-26)23-20-10-17-29-21(20)8-11-24-23/h8,11,18-19H,4-7,9-10,12-17H2,1H3,(H,25,28)/t18-,19- XDPTVFIWUAWOLA-WGSAOQKQSA-N 106493 US8586579, 82 D(2) dopamine receptor Homo sapiens 425.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768829 174008804 ZINC96177397 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224964 O=CN[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C20H30N4O2/c25-15-22-17-3-1-16(2-4-17)6-9-23-10-12-24(13-11-23)20-18-7-14-26-19(18)5-8-21-20/h5,8,15-17H,1-4,6-7,9-14H2,(H,22,25)/t16-,17- ABHVAQKOVOLZPM-QAQDUYKDSA-N 106494 US8586579, 110 D(2) dopamine receptor Homo sapiens 837.2 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106494&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86660553 174008805 C06049 ZINC96177398 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224965 Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4OCCc34)CC2)on1 InChI=1S/C25H35N5O3/c1-18-16-21(33-28-18)17-24(31)27-20-4-2-19(3-5-20)7-10-29-11-13-30(14-12-29)25-22-8-15-32-23(22)6-9-26-25/h6,9,16,19-20H,2-5,7-8,10-15,17H2,1H3,(H,27,31)/t19-,20- ZPEAQOHSKIPYKV-MXVIHJGJSA-N 106495 US8586579, 84 D(2) dopamine receptor Homo sapiens 1304.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768830 174008806 ZINC96177399 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224966 Cc1cc(on1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H33N5O3/c1-17-16-22(32-27-17)24(30)26-19-4-2-18(3-5-19)7-10-28-11-13-29(14-12-28)23-20-8-15-31-21(20)6-9-25-23/h6,9,16,18-19H,2-5,7-8,10-15H2,1H3,(H,26,30)/t18-,19- FUAJGUYRNZZDBH-WGSAOQKQSA-N 106496 US8586579, 112 D(2) dopamine receptor Homo sapiens 396.8 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106496&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768831 174008807 ZINC96177400 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224967 CN(C)C(=O)CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H39N5O3/c1-28(2)24(32)8-7-23(31)27-20-5-3-19(4-6-20)10-13-29-14-16-30(17-15-29)25-21-11-18-33-22(21)9-12-26-25/h9,12,19-20H,3-8,10-11,13-18H2,1-2H3,(H,27,31)/t19-,20- GXVCWWLYAQAZCU-MXVIHJGJSA-N 106497 US8586579, 113 D(2) dopamine receptor Homo sapiens 2562.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768832 174008808 ZINC96177401 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224968 CC(C)(O)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H38N4O3/c1-24(2,30)17-22(29)26-19-5-3-18(4-6-19)8-11-27-12-14-28(15-13-27)23-20-9-16-31-21(20)7-10-25-23/h7,10,18-19,30H,3-6,8-9,11-17H2,1-2H3,(H,26,29)/t18-,19- KLTVYCHNHMTZNG-WGSAOQKQSA-N 106498 US8586579, 114 D(2) dopamine receptor Homo sapiens 999.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125781 174008809 ZINC96177402 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224969 O[C@H](CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)C(F)(F)F InChI=1S/C23H33F3N4O3/c24-23(25,26)20(31)15-21(32)28-17-3-1-16(2-4-17)6-9-29-10-12-30(13-11-29)22-18-7-14-33-19(18)5-8-27-22/h5,8,16-17,20,31H,1-4,6-7,9-15H2,(H,28,32)/t16-,17-,20-/m1/s1 CTMBSXSNFDPMFG-MBOZVWFJSA-N 106499 US8586579, 115 D(2) dopamine receptor Homo sapiens 731.8 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125851 174008810 ZINC96177403 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224970 CC[C@H](O)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H38N4O3/c1-2-20(29)17-23(30)26-19-5-3-18(4-6-19)8-11-27-12-14-28(15-13-27)24-21-9-16-31-22(21)7-10-25-24/h7,10,18-20,29H,2-6,8-9,11-17H2,1H3,(H,26,30)/t18-,19-,20-/m0/s1 JBVSQYZVCXMFCI-UFYCRDLUSA-N 106500 US8586579, 116 D(2) dopamine receptor Homo sapiens 887.4 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125818 174008811 ZINC96177404 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224971 CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4OCCc34)CC2)C1 InChI=1S/C27H42N4O3/c1-33-23-7-4-21(18-23)19-26(32)29-22-5-2-20(3-6-22)9-12-30-13-15-31(16-14-30)27-24-10-17-34-25(24)8-11-28-27/h8,11,20-23H,2-7,9-10,12-19H2,1H3,(H,29,32)/t20-,21-,22-,23-/m0/s1 DQTBCNRIVXHDQE-MLCQCVOFSA-N 106501 US8586579, 117 D(2) dopamine receptor Homo sapiens 1291.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70653201 174008812 ZINC96177405 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224972 O[C@@H]1COC(CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4OCCc34)CC2)C1 InChI=1S/C25H38N4O4/c30-20-15-21(33-17-20)16-24(31)27-19-3-1-18(2-4-19)6-9-28-10-12-29(13-11-28)25-22-7-14-32-23(22)5-8-26-25/h5,8,18-21,30H,1-4,6-7,9-17H2,(H,27,31)/t18-,19-,20-,21?/m0/s1 XIVALFSMOKTRNY-AVJWEPTDSA-N 106502 US8586579, 118 D(2) dopamine receptor Homo sapiens 926.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125839 174008813 ZINC96177407 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224973 CCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H36N4O2/c1-2-3-22(28)25-19-6-4-18(5-7-19)9-12-26-13-15-27(16-14-26)23-20-10-17-29-21(20)8-11-24-23/h8,11,18-19H,2-7,9-10,12-17H2,1H3,(H,25,28)/t18-,19- ABKVEMFUXMVUSG-WGSAOQKQSA-N 106503 US8586579, 119 D(2) dopamine receptor Homo sapiens 828.3 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125780 174008814 ZINC96177408 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224974 CC(C)CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H40N4O2/c1-19(2)3-8-24(30)27-21-6-4-20(5-7-21)10-13-28-14-16-29(17-15-28)25-22-11-18-31-23(22)9-12-26-25/h9,12,19-21H,3-8,10-11,13-18H2,1-2H3,(H,27,30)/t20-,21- VMDGNXGFFZHOON-MEMLXQNLSA-N 106504 US8586579, 120 D(2) dopamine receptor Homo sapiens 1277.1 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125802 174008815 ZINC96177409 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224975 CCCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H38N4O2/c1-2-3-4-23(29)26-20-7-5-19(6-8-20)10-13-27-14-16-28(17-15-27)24-21-11-18-30-22(21)9-12-25-24/h9,12,19-20H,2-8,10-11,13-18H2,1H3,(H,26,29)/t19-,20- QVISYVCUOQJANU-MXVIHJGJSA-N 106505 US8586579, 121 D(2) dopamine receptor Homo sapiens 1143.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70652534 174008816 ZINC96177410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224976 FC(F)(F)CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H33F3N4O2/c24-23(25,26)9-5-21(31)28-18-3-1-17(2-4-18)7-11-29-12-14-30(15-13-29)22-19-8-16-32-20(19)6-10-27-22/h6,10,17-18H,1-5,7-9,11-16H2,(H,28,31)/t17-,18- QDQDDWWAKHSCSK-IYARVYRRSA-N 106506 US8586579, 122 D(2) dopamine receptor Homo sapiens 1253.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125799 174008817 ZINC96177411 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224977 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nc(C)cc3occc23)CC1 InChI=1S/C22H32N4O2/c1-16-15-21-20(8-14-28-21)22(23-16)26-12-10-25(11-13-26)9-7-18-3-5-19(6-4-18)24-17(2)27/h8,14-15,18-19H,3-7,9-13H2,1-2H3,(H,24,27)/t18-,19- QGKIQQCQAJMJNK-WGSAOQKQSA-N 106507 US8586579, 96 D(2) dopamine receptor Homo sapiens 248.8 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106507&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125808 174008818 ZINC96177412 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224978 Cc1cc2occc2c(n1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2CCOCC2)CC1 InChI=1S/C26H38N4O3/c1-19-18-24-23(9-17-33-24)25(27-19)30-13-11-29(12-14-30)10-6-20-2-4-22(5-3-20)28-26(31)21-7-15-32-16-8-21/h9,17-18,20-22H,2-8,10-16H2,1H3,(H,28,31)/t20-,22- GRSPAVQNQLAIED-AQYVVDRMSA-N 106508 US8586579, 124 D(2) dopamine receptor Homo sapiens 274.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125803 174008819 ZINC96177413 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224979 Cc1cc2occc2c(n1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)CC2CCOCC2)CC1 InChI=1S/C27H40N4O3/c1-20-18-25-24(9-17-34-25)27(28-20)31-13-11-30(12-14-31)10-6-21-2-4-23(5-3-21)29-26(32)19-22-7-15-33-16-8-22/h9,17-18,21-23H,2-8,10-16,19H2,1H3,(H,29,32)/t21-,23- KGHICJQDLKRYCB-AFARHQOCSA-N 106509 US8586579, 98 D(2) dopamine receptor Homo sapiens 640.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125771 174008820 ZINC96177414 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224980 COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nc(C)cc3occc23)CC1 InChI=1S/C24H36N4O3/c1-18-17-22-21(8-16-31-22)24(25-18)28-13-11-27(12-14-28)10-7-19-3-5-20(6-4-19)26-23(29)9-15-30-2/h8,16-17,19-20H,3-7,9-15H2,1-2H3,(H,26,29)/t19-,20- PVAIEWDYRNQJFR-MXVIHJGJSA-N 106510 US8586579, 99 D(2) dopamine receptor Homo sapiens 429.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125797 174008821 ZINC96177415 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224981 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nc(C)cc3OCCc23)CC1 InChI=1S/C22H34N4O2/c1-16-15-21-20(8-14-28-21)22(23-16)26-12-10-25(11-13-26)9-7-18-3-5-19(6-4-18)24-17(2)27/h15,18-19H,3-14H2,1-2H3,(H,24,27)/t18-,19- VLMVFBMJXRVZOG-WGSAOQKQSA-N 106511 US8586579, 100 D(2) dopamine receptor Homo sapiens 915 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125856 174008822 ZINC96177416 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224982 Cc1cc2OCCc2c(n1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2CCOCC2)CC1 InChI=1S/C26H40N4O3/c1-19-18-24-23(9-17-33-24)25(27-19)30-13-11-29(12-14-30)10-6-20-2-4-22(5-3-20)28-26(31)21-7-15-32-16-8-21/h18,20-22H,2-17H2,1H3,(H,28,31)/t20-,22- ITNGDGJSTGEEEQ-AQYVVDRMSA-N 106512 US8586579, 128 D(2) dopamine receptor Homo sapiens 1950 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125785 174008823 ZINC96177417 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224983 Cc1cc2OCCc2c(n1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)CC2CCOCC2)CC1 InChI=1S/C27H42N4O3/c1-20-18-25-24(9-17-34-25)27(28-20)31-13-11-30(12-14-31)10-6-21-2-4-23(5-3-21)29-26(32)19-22-7-15-33-16-8-22/h18,21-23H,2-17,19H2,1H3,(H,29,32)/t21-,23- QGUAUKGVRXXHQV-AFARHQOCSA-N 106513 US8586579, 129 D(2) dopamine receptor Homo sapiens 1935 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768833 174008824 ZINC96177418 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224984 COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nc(C)cc3OCCc23)CC1 InChI=1S/C24H38N4O3/c1-18-17-22-21(8-16-31-22)24(25-18)28-13-11-27(12-14-28)10-7-19-3-5-20(6-4-19)26-23(29)9-15-30-2/h17,19-20H,3-16H2,1-2H3,(H,26,29)/t19-,20- RCSLPJAWSBFTLD-MXVIHJGJSA-N 106514 US8586579, 103 D(2) dopamine receptor Homo sapiens 1486 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125782 174008825 ZINC96177419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224985 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ncc(C)c3occc23)CC1 InChI=1S/C22H32N4O2/c1-16-15-23-22(20-8-14-28-21(16)20)26-12-10-25(11-13-26)9-7-18-3-5-19(6-4-18)24-17(2)27/h8,14-15,18-19H,3-7,9-13H2,1-2H3,(H,24,27)/t18-,19- ALJNGMYHXPZTTG-WGSAOQKQSA-N 106515 US8586579, 131 D(2) dopamine receptor Homo sapiens 1461 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771296 174008826 ZINC96177420 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224986 Cc1cnc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCOCC3)CC2)c2ccoc12 InChI=1S/C26H38N4O3/c1-19-18-27-25(23-9-17-33-24(19)23)30-13-11-29(12-14-30)10-6-20-2-4-22(5-3-20)28-26(31)21-7-15-32-16-8-21/h9,17-18,20-22H,2-8,10-16H2,1H3,(H,28,31)/t20-,22- XZKJWFNUAUOHAC-AQYVVDRMSA-N 106516 US8586579, 105 D(2) dopamine receptor Homo sapiens 1126 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771508 174008827 ZINC96177421 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224987 Cc1cnc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)CC3CCOCC3)CC2)c2ccoc12 InChI=1S/C27H40N4O3/c1-20-19-28-27(24-9-17-34-26(20)24)31-13-11-30(12-14-31)10-6-21-2-4-23(5-3-21)29-25(32)18-22-7-15-33-16-8-22/h9,17,19,21-23H,2-8,10-16,18H2,1H3,(H,29,32)/t21-,23- JTMYPGNBDACXLP-AFARHQOCSA-N 106517 US8586579, 106 D(2) dopamine receptor Homo sapiens 2718 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771509 174008828 ZINC96177422 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224988 COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ncc(C)c3occc23)CC1 InChI=1S/C24H36N4O3/c1-18-17-25-24(21-8-16-31-23(18)21)28-13-11-27(12-14-28)10-7-19-3-5-20(6-4-19)26-22(29)9-15-30-2/h8,16-17,19-20H,3-7,9-15H2,1-2H3,(H,26,29)/t19-,20- XPRRZXPFKHAHFH-MXVIHJGJSA-N 106518 US8586579, 107 D(2) dopamine receptor Homo sapiens 2471 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771510 174008829 ZINC96177423 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224989 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ncc(C)c3OCCc23)CC1 InChI=1S/C22H34N4O2/c1-16-15-23-22(20-8-14-28-21(16)20)26-12-10-25(11-13-26)9-7-18-3-5-19(6-4-18)24-17(2)27/h15,18-19H,3-14H2,1-2H3,(H,24,27)/t18-,19- ACEAZRLEPRIAMD-WGSAOQKQSA-N 106519 US8586579, 135 D(2) dopamine receptor Homo sapiens 2308 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125815 174008830 ZINC96177424 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224990 Cc1cnc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCOCC3)CC2)c2CCOc12 InChI=1S/C26H40N4O3/c1-19-18-27-25(23-9-17-33-24(19)23)30-13-11-29(12-14-30)10-6-20-2-4-22(5-3-20)28-26(31)21-7-15-32-16-8-21/h18,20-22H,2-17H2,1H3,(H,28,31)/t20-,22- KMPUTTSRRTYIRY-AQYVVDRMSA-N 106520 US8586579, 136 D(2) dopamine receptor Homo sapiens 4510 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125809 174008831 ZINC96177425 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224991 Cc1cnc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)CC3CCOCC3)CC2)c2CCOc12 InChI=1S/C27H42N4O3/c1-20-19-28-27(24-9-17-34-26(20)24)31-13-11-30(12-14-31)10-6-21-2-4-23(5-3-21)29-25(32)18-22-7-15-33-16-8-22/h19,21-23H,2-18H2,1H3,(H,29,32)/t21-,23- ADDORVGWJJXKFK-AFARHQOCSA-N 106521 US8586579, 137 D(2) dopamine receptor Homo sapiens 2951 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125884 174008832 ZINC96177426 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224992 COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ncc(C)c3OCCc23)CC1 InChI=1S/C24H38N4O3/c1-18-17-25-24(21-8-16-31-23(18)21)28-13-11-27(12-14-28)10-7-19-3-5-20(6-4-19)26-22(29)9-15-30-2/h17,19-20H,3-16H2,1-2H3,(H,26,29)/t19-,20- OZUAEHNGHNUWOV-MXVIHJGJSA-N 106522 US8586579, 138 D(2) dopamine receptor Homo sapiens 3564 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771511 174008833 ZINC96177427 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224993 OC(C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)C(F)(F)F InChI=1S/C22H31F3N4O3/c23-22(24,25)19(30)21(31)27-16-3-1-15(2-4-16)6-9-28-10-12-29(13-11-28)20-17-7-14-32-18(17)5-8-26-20/h5,8,15-16,19,30H,1-4,6-7,9-14H2,(H,27,31)/t15-,16-,19? PMYFBYDQSGEVHT-DBTMUERSSA-N 106523 US8586579, 112 D(2) dopamine receptor Homo sapiens 842.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106523&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771512 174008834 ZINC96177429 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224994 COC(CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)OC InChI=1S/C24H38N4O4/c1-30-23(31-2)17-22(29)26-19-5-3-18(4-6-19)8-11-27-12-14-28(15-13-27)24-20-9-16-32-21(20)7-10-25-24/h7,10,18-19,23H,3-6,8-9,11-17H2,1-2H3,(H,26,29)/t18-,19- AVYIORKUKBQLOA-WGSAOQKQSA-N 106524 US8586579, 140 D(2) dopamine receptor Homo sapiens 1384.9 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106524&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125824 174008835 ZINC96177430 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224995 COC(CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)OC InChI=1S/C25H40N4O4/c1-31-24(32-2)8-7-23(30)27-20-5-3-19(4-6-20)10-13-28-14-16-29(17-15-28)25-21-11-18-33-22(21)9-12-26-25/h9,12,19-20,24H,3-8,10-11,13-18H2,1-2H3,(H,27,30)/t19-,20- LIWZXUWAEHOPHY-MXVIHJGJSA-N 106525 US8586579, 141 D(2) dopamine receptor Homo sapiens 2365.4 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125791 174008836 ZINC96177431 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224996 CS(=O)(=O)c1ccc(s1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C25H34N4O4S2/c1-35(31,32)23-7-6-22(34-23)25(30)27-19-4-2-18(3-5-19)9-12-28-13-15-29(16-14-28)24-20-10-17-33-21(20)8-11-26-24/h6-8,11,18-19H,2-5,9-10,12-17H2,1H3,(H,27,30)/t18-,19- HWZBTMUYGJHELF-WGSAOQKQSA-N 106526 US8586579, 115 D(2) dopamine receptor Homo sapiens 516 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125814 174008837 ZINC96177432 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224997 Cc1ccc(cn1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C26H35N5O2/c1-19-2-5-21(18-28-19)26(32)29-22-6-3-20(4-7-22)9-12-30-13-15-31(16-14-30)25-23-10-17-33-24(23)8-11-27-25/h2,5,8,11,18,20,22H,3-4,6-7,9-10,12-17H2,1H3,(H,29,32)/t20-,22- UNPARBQWWULNRE-AQYVVDRMSA-N 106527 US8586579, 143 D(2) dopamine receptor Homo sapiens 312.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54769063 174008838 ZINC96177433 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224998 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(cc1)C#N InChI=1S/C27H33N5O2/c28-19-21-1-5-22(6-2-21)27(33)30-23-7-3-20(4-8-23)10-13-31-14-16-32(17-15-31)26-24-11-18-34-25(24)9-12-29-26/h1-2,5-6,9,12,20,23H,3-4,7-8,10-11,13-18H2,(H,30,33)/t20-,23- MHYHDPMWTXPZLG-JKIUYZKVSA-N 106528 US8586579, 144 D(2) dopamine receptor Homo sapiens 381.2 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54768834 174008839 ZINC96177434 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 224999 CN1CCN(CC1)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C31H44N6O2/c1-34-15-19-36(20-16-34)27-8-4-25(5-9-27)31(38)33-26-6-2-24(3-7-26)11-14-35-17-21-37(22-18-35)30-28-12-23-39-29(28)10-13-32-30/h4-5,8-10,13,24,26H,2-3,6-7,11-12,14-23H2,1H3,(H,33,38)/t24-,26- FNDLZQGZKLRGIU-YOCNBXQISA-N 106529 US8586579, 118 D(2) dopamine receptor Homo sapiens 179.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106529&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771736 174008840 ZINC96177435 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225000 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(nc1)N1CCOCC1 InChI=1S/C29H40N6O3/c36-29(23-3-6-27(31-21-23)34-16-19-37-20-17-34)32-24-4-1-22(2-5-24)8-11-33-12-14-35(15-13-33)28-25-9-18-38-26(25)7-10-30-28/h3,6-7,10,21-22,24H,1-2,4-5,8-9,11-20H2,(H,32,36)/t22-,24- SWYRWYLIJXJVNV-HCGLCNNCSA-N 106530 US8586579, 146 D(2) dopamine receptor Homo sapiens 998.4 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771737 174008841 ZINC96177436 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225001 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(cc1)-c1cccnc1 InChI=1S/C31H37N5O2/c37-31(25-7-5-24(6-8-25)26-2-1-14-32-22-26)34-27-9-3-23(4-10-27)12-16-35-17-19-36(20-18-35)30-28-13-21-38-29(28)11-15-33-30/h1-2,5-8,11,14-15,22-23,27H,3-4,9-10,12-13,16-21H2,(H,34,37)/t23-,27- SBHJIEDINHIMAF-JIBACQESSA-N 106531 US8586579, 120 D(2) dopamine receptor Homo sapiens 222.9 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125836 174008842 ZINC96177437 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225002 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc2OCOc2c1 InChI=1S/C27H34N4O4/c32-27(20-3-6-24-25(17-20)35-18-34-24)29-21-4-1-19(2-5-21)8-11-30-12-14-31(15-13-30)26-22-9-16-33-23(22)7-10-28-26/h3,6-7,10,17,19,21H,1-2,4-5,8-9,11-16,18H2,(H,29,32)/t19-,21- CEMWPWPBXGCHCV-XUTJKUGGSA-N 106532 US8586579, 148 D(2) dopamine receptor Homo sapiens 3372 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771738 174008843 ZINC96177438 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225003 O=C(Cc1ccc2OCOc2c1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C28H36N4O4/c33-27(18-21-3-6-25-26(17-21)36-19-35-25)30-22-4-1-20(2-5-22)8-11-31-12-14-32(15-13-31)28-23-9-16-34-24(23)7-10-29-28/h3,6-7,10,17,20,22H,1-2,4-5,8-9,11-16,18-19H2,(H,30,33)/t20-,22- ONAUJHKYHSJWDK-AQYVVDRMSA-N 106533 US8586579, 149 D(2) dopamine receptor Homo sapiens 3042 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771739 174008844 ZINC96177439 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225004 OC1(CCC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H36N4O3/c29-23(24(30)9-1-10-24)26-19-4-2-18(3-5-19)7-12-27-13-15-28(16-14-27)22-20-8-17-31-21(20)6-11-25-22/h6,11,18-19,30H,1-5,7-10,12-17H2,(H,26,29)/t18-,19- WPDISOIHGGRFRZ-WGSAOQKQSA-N 106534 US8586579, 123 D(2) dopamine receptor Homo sapiens 958.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771740 174008845 ZINC96177440 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225005 CC(C)(O)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H36N4O3/c1-23(2,29)22(28)25-18-5-3-17(4-6-18)8-11-26-12-14-27(15-13-26)21-19-9-16-30-20(19)7-10-24-21/h7,10,17-18,29H,3-6,8-9,11-16H2,1-2H3,(H,25,28)/t17-,18- ZATCCWHVTMAUCE-IYARVYRRSA-N 106535 US8586579, 124 D(2) dopamine receptor Homo sapiens 1265 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125837 174008846 ZINC96177441 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225006 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(cc1)N1CCS(=O)(=O)CC1 InChI=1S/C30H41N5O4S/c36-30(24-3-7-26(8-4-24)34-18-21-40(37,38)22-19-34)32-25-5-1-23(2-6-25)10-13-33-14-16-35(17-15-33)29-27-11-20-39-28(27)9-12-31-29/h3-4,7-9,12,23,25H,1-2,5-6,10-11,13-22H2,(H,32,36)/t23-,25- JUAVLXRBQKTSPW-ALOJWSFFSA-N 106536 US8586579, 152 D(2) dopamine receptor Homo sapiens 116.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125857 174008847 ZINC96177442 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225007 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(cc1)-n1cccn1 InChI=1S/C29H36N6O2/c36-29(23-4-8-25(9-5-23)35-15-1-13-31-35)32-24-6-2-22(3-7-24)11-16-33-17-19-34(20-18-33)28-26-12-21-37-27(26)10-14-30-28/h1,4-5,8-10,13-15,22,24H,2-3,6-7,11-12,16-21H2,(H,32,36)/t22-,24- BNGQWOSQOPVKCC-HCGLCNNCSA-N 106537 US8586579, 153 D(2) dopamine receptor Homo sapiens 478 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125848 174008848 ZINC96177443 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225008 Cc1nc(no1)-c1cccc(c1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C29H36N6O3/c1-20-31-27(33-38-20)22-3-2-4-23(19-22)29(36)32-24-7-5-21(6-8-24)10-13-34-14-16-35(17-15-34)28-25-11-18-37-26(25)9-12-30-28/h2-4,9,12,19,21,24H,5-8,10-11,13-18H2,1H3,(H,32,36)/t21-,24- DZYJECJNISMMEC-SAIGFBBZSA-N 106538 US8586579, 154 D(2) dopamine receptor Homo sapiens 2147 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771971 174008849 ZINC96177444 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225009 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc2ncccc2c1 InChI=1S/C29H35N5O2/c35-29(23-5-8-26-22(20-23)2-1-12-30-26)32-24-6-3-21(4-7-24)10-14-33-15-17-34(18-16-33)28-25-11-19-36-27(25)9-13-31-28/h1-2,5,8-9,12-13,20-21,24H,3-4,6-7,10-11,14-19H2,(H,32,35)/t21-,24- ATHCQCSSVYPJIN-SAIGFBBZSA-N 106539 US8586579, 155 D(2) dopamine receptor Homo sapiens 500.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771972 174008850 ZINC96177445 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225010 O=C(Cc1noc2ccccc12)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C28H35N5O3/c34-27(19-24-22-3-1-2-4-26(22)36-31-24)30-21-7-5-20(6-8-21)10-13-32-14-16-33(17-15-32)28-23-11-18-35-25(23)9-12-29-28/h1-4,9,12,20-21H,5-8,10-11,13-19H2,(H,30,34)/t20-,21- MWMCOQFLGVOAHE-MEMLXQNLSA-N 106540 US8586579, 156 D(2) dopamine receptor Homo sapiens 1308.9 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106540&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771973 174008851 ZINC96177446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225011 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1cnc(cn1)N1CCOCC1 InChI=1S/C28H39N7O3/c36-28(24-19-31-26(20-30-24)34-14-17-37-18-15-34)32-22-3-1-21(2-4-22)6-9-33-10-12-35(13-11-33)27-23-7-16-38-25(23)5-8-29-27/h5,8,19-22H,1-4,6-7,9-18H2,(H,32,36)/t21-,22- MTJDLXLLSRKTMU-HZCBDIJESA-N 106541 US8586579, 157 D(2) dopamine receptor Homo sapiens 506 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125784 174008852 ZINC96177447 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225012 CC(C)(C)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C30H42N4O2/c1-30(2,3)24-8-6-23(7-9-24)29(35)32-25-10-4-22(5-11-25)13-16-33-17-19-34(20-18-33)28-26-14-21-36-27(26)12-15-31-28/h6-9,12,15,22,25H,4-5,10-11,13-14,16-21H2,1-3H3,(H,32,35)/t22-,25- ZZJDFRAENYUPMH-RZFKFIIISA-N 106542 US8586579, 158 D(2) dopamine receptor Homo sapiens 1663 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106542&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771974 174008853 ZINC96177448 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225013 Clc1ccc(C(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4OCCc34)CC2)c(Cl)c1 InChI=1S/C26H32Cl2N4O2/c27-19-3-6-21(23(28)17-19)26(33)30-20-4-1-18(2-5-20)8-11-31-12-14-32(15-13-31)25-22-9-16-34-24(22)7-10-29-25/h3,6-7,10,17-18,20H,1-2,4-5,8-9,11-16H2,(H,30,33)/t18-,20- KVMPVICKYUXJEP-KESTWPANSA-N 106543 US8586579, 159 D(2) dopamine receptor Homo sapiens 518.3 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54771975 174008854 ZINC96177449 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225014 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(cc1)-n1cccc1 InChI=1S/C30H37N5O2/c36-30(24-5-9-26(10-6-24)34-15-1-2-16-34)32-25-7-3-23(4-8-25)12-17-33-18-20-35(21-19-33)29-27-13-22-37-28(27)11-14-31-29/h1-2,5-6,9-11,14-16,23,25H,3-4,7-8,12-13,17-22H2,(H,32,36)/t23-,25- HIUMOAWWYUAXFP-ALOJWSFFSA-N 106544 US8586579, 160 D(2) dopamine receptor Homo sapiens 163.3 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54772198 174008855 ZINC96177450 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225015 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccc(cc1)-c1ccccc1 InChI=1S/C32H38N4O2/c37-32(27-10-8-26(9-11-27)25-4-2-1-3-5-25)34-28-12-6-24(7-13-28)15-18-35-19-21-36(22-20-35)31-29-16-23-38-30(29)14-17-33-31/h1-5,8-11,14,17,24,28H,6-7,12-13,15-16,18-23H2,(H,34,37)/t24-,28- ZQZUTJSBLPRYPL-XBTDCMMSSA-N 106545 US8586579, 161 D(2) dopamine receptor Homo sapiens 1132 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54772199 174008856 ZINC96177451 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225016 CO[C@H](C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H36N4O3/c1-17(29-2)23(28)25-19-5-3-18(4-6-19)8-11-26-12-14-27(15-13-26)22-20-9-16-30-21(20)7-10-24-22/h7,10,17-19H,3-6,8-9,11-16H2,1-2H3,(H,25,28)/t17-,18-,19-/m1/s1 XHSRFVQGNJCGAD-GUDVDZBRSA-N 106546 US8586579, 135 D(2) dopamine receptor Homo sapiens 680.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125792 174008857 ZINC96177452 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225017 CC(C)(C)Oc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C30H42N4O3/c1-30(2,3)37-25-10-6-23(7-11-25)29(35)32-24-8-4-22(5-9-24)13-16-33-17-19-34(20-18-33)28-26-14-21-36-27(26)12-15-31-28/h6-7,10-12,15,22,24H,4-5,8-9,13-14,16-21H2,1-3H3,(H,32,35)/t22-,24- OAIALYFMHHTONS-HCGLCNNCSA-N 106547 US8586579, 163 D(2) dopamine receptor Homo sapiens 3161 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125776 174008858 ZINC96177453 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225018 CO[C@@H](C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C23H36N4O3/c1-17(29-2)23(28)25-19-5-3-18(4-6-19)8-11-26-12-14-27(15-13-26)22-20-9-16-30-21(20)7-10-24-22/h7,10,17-19H,3-6,8-9,11-16H2,1-2H3,(H,25,28)/t17-,18-,19-/m0/s1 XHSRFVQGNJCGAD-FHWLQOOXSA-N 106548 US8586579, 164 D(2) dopamine receptor Homo sapiens 788.5 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54772200 174008859 ZINC96177454 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225019 O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1)c1ccccc1 InChI=1S/C25H34N4O3S/c30-33(31,22-4-2-1-3-5-22)27-21-8-6-20(7-9-21)11-14-28-15-17-29(18-16-28)25-23-12-19-32-24(23)10-13-26-25/h1-5,10,13,20-21,27H,6-9,11-12,14-19H2/t20-,21- LWUHTASBTHFHOH-MEMLXQNLSA-N 106549 US8586579, 165 D(2) dopamine receptor Homo sapiens 242.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54772201 174008860 ZINC96177455 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225020 COC(C)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H38N4O3/c1-18(30-2)17-23(29)26-20-5-3-19(4-6-20)8-11-27-12-14-28(15-13-27)24-21-9-16-31-22(21)7-10-25-24/h7,10,18-20H,3-6,8-9,11-17H2,1-2H3,(H,26,29)/t18?,19-,20- ROGRQIGZHYODFP-JUUMZCOKSA-N 106550 US8586579, 166 D(2) dopamine receptor Homo sapiens 801.3 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125846 174008861 ZINC96177457 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225021 CC[C@@H](O)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nccc3OCCc23)CC1 InChI=1S/C24H38N4O3/c1-2-20(29)17-23(30)26-19-5-3-18(4-6-19)8-11-27-12-14-28(15-13-27)24-21-9-16-31-22(21)7-10-25-24/h7,10,18-20,29H,2-6,8-9,11-17H2,1H3,(H,26,30)/t18-,19-,20-/m1/s1 JBVSQYZVCXMFCI-VAMGGRTRSA-N 106551 US8586579, 167 D(2) dopamine receptor Homo sapiens 842.7 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54772202 174008862 ZINC96177458 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 225022 OC1(CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4OCCc34)CC2)CCC1 InChI=1S/C25H38N4O3/c30-23(18-25(31)9-1-10-25)27-20-4-2-19(3-5-20)7-12-28-13-15-29(16-14-28)24-21-8-17-32-22(21)6-11-26-24/h6,11,19-20,31H,1-5,7-10,12-18H2,(H,27,30)/t19-,20- AVJAAHWPEDARHN-MXVIHJGJSA-N 106552 US8586579, 168 D(2) dopamine receptor Homo sapiens 408.6 US Patent 10.7270/Q2QV3K55 aid1800145 US8586579 Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106552&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67125834 174008863 ZINC96177459 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227127 CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H32N2O3/c1-16(25)23-19-7-5-17(6-8-19)9-12-24-13-10-18(11-14-24)20-3-2-4-21-22(20)27-15-26-21/h2-4,17-19H,5-15H2,1H3,(H,23,25)/t17-,19- URKYBTISJBKTKP-UAPYVXQJSA-N 107498 US8598357, 1 D(2) dopamine receptor Homo sapiens 253.68 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196663 175444945 ZINC96178416 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227128 COCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H36N2O4/c1-28-16-12-23(27)25-20-7-5-18(6-8-20)9-13-26-14-10-19(11-15-26)21-3-2-4-22-24(21)30-17-29-22/h2-4,18-20H,5-17H2,1H3,(H,25,27)/t18-,20- CBQSITUTOXWCDZ-KESTWPANSA-N 107499 US8598357, 2 D(2) dopamine receptor Homo sapiens 426.60 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196664 175444946 ZINC96178417 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227129 O=C(CC1COCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H38N2O5/c29-25(16-22-17-30-14-15-31-22)27-21-6-4-19(5-7-21)8-11-28-12-9-20(10-13-28)23-2-1-3-24-26(23)33-18-32-24/h1-3,19-22H,4-18H2,(H,27,29)/t19-,21-,22? CFTKIUKLSZSRGT-LFKXIUMZSA-N 107500 US8598357, 3 D(2) dopamine receptor Homo sapiens 529.67 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196665 175444947 ZINC96178419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227130 O=C(C[C@H]1COCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H38N2O5/c29-25(16-22-17-30-14-15-31-22)27-21-6-4-19(5-7-21)8-11-28-12-9-20(10-13-28)23-2-1-3-24-26(23)33-18-32-24/h1-3,19-22H,4-18H2,(H,27,29)/t19-,21-,22-/m0/s1 CFTKIUKLSZSRGT-BVSLBCMMSA-N 107501 US8598357, 4 D(2) dopamine receptor Homo sapiens 467.56 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196764 175444948 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227131 O=C(C[C@@H]1COCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H38N2O5/c29-25(16-22-17-30-14-15-31-22)27-21-6-4-19(5-7-21)8-11-28-12-9-20(10-13-28)23-2-1-3-24-26(23)33-18-32-24/h1-3,19-22H,4-18H2,(H,27,29)/t19-,21-,22-/m1/s1 CFTKIUKLSZSRGT-CEMLEFRQSA-N 107502 US8598357, 5 D(2) dopamine receptor Homo sapiens 332.35 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196765 175444949 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227132 O=C(CC1CCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H38N2O4/c29-25(17-22-3-2-16-30-22)27-21-8-6-19(7-9-21)10-13-28-14-11-20(12-15-28)23-4-1-5-24-26(23)32-18-31-24/h1,4-5,19-22H,2-3,6-18H2,(H,27,29)/t19-,21-,22? LAGLIYNPBAJZEJ-LFKXIUMZSA-N 107503 US8598357, 6 D(2) dopamine receptor Homo sapiens 389.06 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196766 175444950 ZINC96178421 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227133 CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H34N2O3/c1-2-22(26)24-19-8-6-17(7-9-19)10-13-25-14-11-18(12-15-25)20-4-3-5-21-23(20)28-16-27-21/h3-5,17-19H,2,6-16H2,1H3,(H,24,26)/t17-,19- HOJGYADNYPGADT-UAPYVXQJSA-N 107504 US8598357, 7 D(2) dopamine receptor Homo sapiens 203.61 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196767 175444951 ZINC96178422 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227134 O=C(CC1CC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H36N2O3/c28-24(16-19-4-5-19)26-21-8-6-18(7-9-21)10-13-27-14-11-20(12-15-27)22-2-1-3-23-25(22)30-17-29-23/h1-3,18-21H,4-17H2,(H,26,28)/t18-,21- WTONWMINNVVDTM-XGAFWQRZSA-N 107505 US8598357, 8 D(2) dopamine receptor Homo sapiens 302.84 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196768 175444952 ZINC96178423 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227135 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)c1ccccc1 InChI=1S/C27H34N2O3/c30-27(22-5-2-1-3-6-22)28-23-11-9-20(10-12-23)13-16-29-17-14-21(15-18-29)24-7-4-8-25-26(24)32-19-31-25/h1-8,20-21,23H,9-19H2,(H,28,30)/t20-,23- KTBHNUYISHHNFW-JKIUYZKVSA-N 107506 US8598357, 9 D(2) dopamine receptor Homo sapiens 120.38 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197890 175444953 ZINC96178424 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227136 FC(F)(F)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H31F3N2O3/c24-23(25,26)14-21(29)27-18-6-4-16(5-7-18)8-11-28-12-9-17(10-13-28)19-2-1-3-20-22(19)31-15-30-20/h1-3,16-18H,4-15H2,(H,27,29)/t16-,18- VBNZKUKNBGOHDO-SAABIXHNSA-N 107507 US8598357, 10 D(2) dopamine receptor Homo sapiens 209.41 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107507&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70656948 175444954 ZINC96178425 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 228521 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.7 US Patent 10.7270/Q28K77RC aid1800221 US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 228522 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 1.6 US Patent 10.7270/Q28K77RC aid1800221 US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 228523 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 190 US Patent 10.7270/Q28K77RC aid1800221 US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 228524 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Homo sapiens 31 US Patent 10.7270/Q28K77RC aid1800221 US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 228525 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Homo sapiens 400 US Patent 10.7270/Q28K77RC aid1800221 US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 228526 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 5.9 US Patent 10.7270/Q28K77RC aid1800221 US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 228527 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Homo sapiens 5 US Patent 10.7270/Q28K77RC aid1800221 US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227137 FC(F)(F)CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H33F3N2O3/c25-24(26,27)12-8-22(30)28-19-6-4-17(5-7-19)9-13-29-14-10-18(11-15-29)20-2-1-3-21-23(20)32-16-31-21/h1-3,17-19H,4-16H2,(H,28,30)/t17-,19- ZCWMQWXQIIXTEH-UAPYVXQJSA-N 107508 US8598357, 11 D(2) dopamine receptor Homo sapiens 410.40 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196769 175444955 ZINC96178426 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227138 OC(C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C(F)(F)F InChI=1S/C23H31F3N2O4/c24-23(25,26)21(29)22(30)27-17-6-4-15(5-7-17)8-11-28-12-9-16(10-13-28)18-2-1-3-19-20(18)32-14-31-19/h1-3,15-17,21,29H,4-14H2,(H,27,30)/t15-,17-,21? UEOLBOREQLRPTL-DVUVRWKGSA-N 107509 US8598357, 12 D(2) dopamine receptor Homo sapiens 235.50 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196864 175444956 ZINC96178428 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227139 COCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H34N2O4/c1-27-15-22(26)24-19-7-5-17(6-8-19)9-12-25-13-10-18(11-14-25)20-3-2-4-21-23(20)29-16-28-21/h2-4,17-19H,5-16H2,1H3,(H,24,26)/t17-,19- GOGFNQYGVYCYHI-UAPYVXQJSA-N 107510 US8598357, 13 D(2) dopamine receptor Homo sapiens 507.18 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196865 175444957 ZINC96178429 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227140 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)c1ccc(cc1)C#N InChI=1S/C28H33N3O3/c29-18-21-4-8-23(9-5-21)28(32)30-24-10-6-20(7-11-24)12-15-31-16-13-22(14-17-31)25-2-1-3-26-27(25)34-19-33-26/h1-5,8-9,20,22,24H,6-7,10-17,19H2,(H,30,32)/t20-,24- DVBIYRUFMRQOAP-LSNLESRRSA-N 107511 US8598357, 14 D(2) dopamine receptor Homo sapiens 152.76 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196866 175444958 ZINC96178430 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227141 Cc1ccc(cn1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H35N3O3/c1-19-5-8-22(17-28-19)27(31)29-23-9-6-20(7-10-23)11-14-30-15-12-21(13-16-30)24-3-2-4-25-26(24)33-18-32-25/h2-5,8,17,20-21,23H,6-7,9-16,18H2,1H3,(H,29,31)/t20-,23- GOXUZWWTKIXHQU-JKIUYZKVSA-N 107512 US8598357, 15 D(2) dopamine receptor Homo sapiens 133.46 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196867 175444959 ZINC96178431 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227142 O=C(C[C@H]1CCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H38N2O4/c29-25(17-22-3-2-16-30-22)27-21-8-6-19(7-9-21)10-13-28-14-11-20(12-15-28)23-4-1-5-24-26(23)32-18-31-24/h1,4-5,19-22H,2-3,6-18H2,(H,27,29)/t19-,21-,22-/m1/s1 LAGLIYNPBAJZEJ-CEMLEFRQSA-N 107513 US8598357, 16 D(2) dopamine receptor Homo sapiens 227.84 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196869 175444960 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227143 O=C(C[C@@H]1CCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H38N2O4/c29-25(17-22-3-2-16-30-22)27-21-8-6-19(7-9-21)10-13-28-14-11-20(12-15-28)23-4-1-5-24-26(23)32-18-31-24/h1,4-5,19-22H,2-3,6-18H2,(H,27,29)/t19-,21-,22-/m0/s1 LAGLIYNPBAJZEJ-BVSLBCMMSA-N 107514 US8598357, 17 D(2) dopamine receptor Homo sapiens 531.19 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196868 175444961 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227144 COC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H32N2O4/c1-26-22(25)23-18-7-5-16(6-8-18)9-12-24-13-10-17(11-14-24)19-3-2-4-20-21(19)28-15-27-20/h2-4,16-18H,5-15H2,1H3,(H,23,25)/t16-,18- XLFVNUMKTSPYMC-SAABIXHNSA-N 107515 US8598357, 18 D(2) dopamine receptor Homo sapiens 133.11 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196965 175444962 ZINC96178432 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227145 Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCOc34)CC2)on1 InChI=1S/C26H35N3O4/c1-18-15-22(33-28-18)16-25(30)27-21-7-5-19(6-8-21)9-12-29-13-10-20(11-14-29)23-3-2-4-24-26(23)32-17-31-24/h2-4,15,19-21H,5-14,16-17H2,1H3,(H,27,30)/t19-,21- VNDRDTRYTOSTBB-XUTJKUGGSA-N 107516 US8598357, 19 D(2) dopamine receptor Homo sapiens 515.70 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165266 175444963 ZINC96178433 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227146 O=C(CC#N)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H31N3O3/c24-12-8-22(27)25-19-6-4-17(5-7-19)9-13-26-14-10-18(11-15-26)20-2-1-3-21-23(20)29-16-28-21/h1-3,17-19H,4-11,13-16H2,(H,25,27)/t17-,19- ZJUQDFIINDCGDS-UAPYVXQJSA-N 107517 US8598357, 20 D(2) dopamine receptor Homo sapiens 202.82 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196966 175444964 ZINC96178434 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227147 OC1(CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCOc34)CC2)CCCCC1 InChI=1S/C28H42N2O4/c31-26(19-28(32)14-2-1-3-15-28)29-23-9-7-21(8-10-23)11-16-30-17-12-22(13-18-30)24-5-4-6-25-27(24)34-20-33-25/h4-6,21-23,32H,1-3,7-20H2,(H,29,31)/t21-,23- DJNLKADPUUFBDG-AFARHQOCSA-N 107518 US8598357, 21 D(2) dopamine receptor Homo sapiens 361.06 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196967 175444965 ZINC96178435 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227148 O=C(CC1CCCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H40N2O4/c30-26(18-23-4-1-2-17-31-23)28-22-9-7-20(8-10-22)11-14-29-15-12-21(13-16-29)24-5-3-6-25-27(24)33-19-32-25/h3,5-6,20-23H,1-2,4,7-19H2,(H,28,30)/t20-,22-,23? VTFHJUTXAYAVPD-YEMPIKNUSA-N 107519 US8598357, 22 D(2) dopamine receptor Homo sapiens 523.08 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196968 175444966 ZINC96178437 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227149 CC(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H36N2O3/c1-17(2)24(27)25-20-8-6-18(7-9-20)10-13-26-14-11-19(12-15-26)21-4-3-5-22-23(21)29-16-28-22/h3-5,17-20H,6-16H2,1-2H3,(H,25,27)/t18-,20- FGGHQCCTGDDYGV-KESTWPANSA-N 107520 US8598357, 23 D(2) dopamine receptor Homo sapiens 397.43 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196969 175444967 ZINC96178438 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227150 CC(C)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H38N2O3/c1-18(2)16-24(28)26-21-8-6-19(7-9-21)10-13-27-14-11-20(12-15-27)22-4-3-5-23-25(22)30-17-29-23/h3-5,18-21H,6-17H2,1-2H3,(H,26,28)/t19-,21- BRANQVYSEMSFOV-XUTJKUGGSA-N 107521 US8598357, 24 D(2) dopamine receptor Homo sapiens 238.80 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60196970 175444968 ZINC96178439 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227151 CCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H36N2O3/c1-2-4-23(27)25-20-9-7-18(8-10-20)11-14-26-15-12-19(13-16-26)21-5-3-6-22-24(21)29-17-28-22/h3,5-6,18-20H,2,4,7-17H2,1H3,(H,25,27)/t18-,20- MLKJSRUZFXLXTL-KESTWPANSA-N 107522 US8598357, 25 D(2) dopamine receptor Homo sapiens 277.39 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197068 175444969 ZINC96178440 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227152 FC1(F)CC1C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H32F2N2O3/c25-24(26)14-20(24)23(29)27-18-6-4-16(5-7-18)8-11-28-12-9-17(10-13-28)19-2-1-3-21-22(19)31-15-30-21/h1-3,16-18,20H,4-15H2,(H,27,29)/t16-,18-,20? GACXEIRXCURUID-QNRJLKAHSA-N 107523 US8598357, 26 D(2) dopamine receptor Homo sapiens 194.24 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107523&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197069 175444970 ZINC96178442 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227153 COC(C)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H38N2O4/c1-18(29-2)16-24(28)26-21-8-6-19(7-9-21)10-13-27-14-11-20(12-15-27)22-4-3-5-23-25(22)31-17-30-23/h3-5,18-21H,6-17H2,1-2H3,(H,26,28)/t18?,19-,21- HVESNMTZXGJVII-OIFYPAEGSA-N 107524 US8598357, 27 D(2) dopamine receptor Homo sapiens 402.37 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107524&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197070 175444971 ZINC96178444 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227154 ClC1CC(C1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H35ClN2O3/c26-20-14-19(15-20)25(29)27-21-6-4-17(5-7-21)8-11-28-12-9-18(10-13-28)22-2-1-3-23-24(22)31-16-30-23/h1-3,17-21H,4-16H2,(H,27,29)/t17-,19?,20?,21- LKGWPHHIJYCDSR-SXFOHPBWSA-N 107525 US8598357, 28 D(2) dopamine receptor Homo sapiens 305.12 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197071 175444972 ZINC96178445 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227155 O=C(CC1COC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H36N2O4/c28-24(14-19-15-29-16-19)26-21-6-4-18(5-7-21)8-11-27-12-9-20(10-13-27)22-2-1-3-23-25(22)31-17-30-23/h1-3,18-21H,4-17H2,(H,26,28)/t18-,21- ICDUPLIIKZSMRC-XGAFWQRZSA-N 107526 US8598357, 29 D(2) dopamine receptor Homo sapiens 258.19 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197072 175444973 ZINC96178446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227156 CO[C@@H]1CC[C@@H](CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCOc34)CC2)C1 InChI=1S/C28H42N2O4/c1-32-24-10-7-21(17-24)18-27(31)29-23-8-5-20(6-9-23)11-14-30-15-12-22(13-16-30)25-3-2-4-26-28(25)34-19-33-26/h2-4,20-24H,5-19H2,1H3,(H,29,31)/t20-,21-,23-,24-/m1/s1 AZFDKPLHCSQHQI-LUGTWXOSSA-N 107527 US8598357, 30 D(2) dopamine receptor Homo sapiens 330.53 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197998 175444974 ZINC96178447 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227157 OC1(CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCOc34)CC2)CCOCC1 InChI=1S/C27H40N2O5/c30-25(18-27(31)11-16-32-17-12-27)28-22-6-4-20(5-7-22)8-13-29-14-9-21(10-15-29)23-2-1-3-24-26(23)34-19-33-24/h1-3,20-22,31H,4-19H2,(H,28,30)/t20-,22- ABOYXIDEOWOTGI-AQYVVDRMSA-N 107528 US8598357, 31 D(2) dopamine receptor Homo sapiens 305.62 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197073 175444975 ZINC96178448 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227158 CC(C)(O)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H36N2O4/c1-24(2,28)23(27)25-19-8-6-17(7-9-19)10-13-26-14-11-18(12-15-26)20-4-3-5-21-22(20)30-16-29-21/h3-5,17-19,28H,6-16H2,1-2H3,(H,25,27)/t17-,19- ZCDUILRTHXKGRD-UAPYVXQJSA-N 107529 US8598357, 32 D(2) dopamine receptor Homo sapiens 406.70 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107529&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197166 175444976 ZINC96178449 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227159 CO[C@@H](C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H36N2O4/c1-17(28-2)24(27)25-20-8-6-18(7-9-20)10-13-26-14-11-19(12-15-26)21-4-3-5-22-23(21)30-16-29-22/h3-5,17-20H,6-16H2,1-2H3,(H,25,27)/t17-,18-,20-/m0/s1 LSKZCQKQGRUHKQ-BJLQDIEVSA-N 107530 US8598357, 33 D(2) dopamine receptor Homo sapiens 463.94 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197167 175444977 ZINC96178450 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227160 CO[C@H](C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H36N2O4/c1-17(28-2)24(27)25-20-8-6-18(7-9-20)10-13-26-14-11-19(12-15-26)21-4-3-5-22-23(21)30-16-29-22/h3-5,17-20H,6-16H2,1-2H3,(H,25,27)/t17-,18-,20-/m1/s1 LSKZCQKQGRUHKQ-QWFCFKBJSA-N 107531 US8598357, 34 D(2) dopamine receptor Homo sapiens 503.95 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197168 175444978 ZINC96178451 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227161 CC(C)(O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H38N2O4/c1-25(2,29)16-23(28)26-20-8-6-18(7-9-20)10-13-27-14-11-19(12-15-27)21-4-3-5-22-24(21)31-17-30-22/h3-5,18-20,29H,6-17H2,1-2H3,(H,26,28)/t18-,20- TVKYQCPWDDYVLL-KESTWPANSA-N 107532 US8598357, 35 D(2) dopamine receptor Homo sapiens 281.84 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197169 175444979 ZINC96178452 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227162 Clc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H33ClN2O3/c28-22-8-6-21(7-9-22)27(31)29-23-10-4-19(5-11-23)12-15-30-16-13-20(14-17-30)24-2-1-3-25-26(24)33-18-32-25/h1-3,6-9,19-20,23H,4-5,10-18H2,(H,29,31)/t19-,23- PMHBIRXUKAOYEK-UILWBTOOSA-N 107533 US8598357, 36 D(2) dopamine receptor Homo sapiens 146.90 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197170 175444980 ZINC96178453 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227163 Fc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H33FN2O3/c28-22-8-6-21(7-9-22)27(31)29-23-10-4-19(5-11-23)12-15-30-16-13-20(14-17-30)24-2-1-3-25-26(24)33-18-32-25/h1-3,6-9,19-20,23H,4-5,10-18H2,(H,29,31)/t19-,23- GYZQENOTEUQFGR-UILWBTOOSA-N 107534 US8598357, 37 D(2) dopamine receptor Homo sapiens 233.95 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197171 175444981 ZINC96178454 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227164 O[C@@H](C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C(F)(F)F InChI=1S/C23H31F3N2O4/c24-23(25,26)21(29)22(30)27-17-6-4-15(5-7-17)8-11-28-12-9-16(10-13-28)18-2-1-3-19-20(18)32-14-31-19/h1-3,15-17,21,29H,4-14H2,(H,27,30)/t15-,17-,21-/m0/s1 UEOLBOREQLRPTL-WJPUGNRLSA-N 107535 US8598357, 38 D(2) dopamine receptor Homo sapiens 208.99 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197269 175444982 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227165 O[C@H](C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C(F)(F)F InChI=1S/C23H31F3N2O4/c24-23(25,26)21(29)22(30)27-17-6-4-15(5-7-17)8-11-28-12-9-16(10-13-28)18-2-1-3-19-20(18)32-14-31-19/h1-3,15-17,21,29H,4-14H2,(H,27,30)/t15-,17-,21-/m1/s1 UEOLBOREQLRPTL-QLVMHMETSA-N 107536 US8598357, 39 D(2) dopamine receptor Homo sapiens 283.73 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197270 175444983 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227166 O=C(C[C@@H]1CCCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H40N2O4/c30-26(18-23-4-1-2-17-31-23)28-22-9-7-20(8-10-22)11-14-29-15-12-21(13-16-29)24-5-3-6-25-27(24)33-19-32-25/h3,5-6,20-23H,1-2,4,7-19H2,(H,28,30)/t20-,22-,23-/m0/s1 VTFHJUTXAYAVPD-PMVMPFDFSA-N 107537 US8598357, 40 D(2) dopamine receptor Homo sapiens 422.11 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197271 175444984 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227167 O=C(C[C@H]1CCCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H40N2O4/c30-26(18-23-4-1-2-17-31-23)28-22-9-7-20(8-10-22)11-14-29-15-12-21(13-16-29)24-5-3-6-25-27(24)33-19-32-25/h3,5-6,20-23H,1-2,4,7-19H2,(H,28,30)/t20-,22-,23-/m1/s1 VTFHJUTXAYAVPD-YMPZKCBVSA-N 107538 US8598357, 41 D(2) dopamine receptor Homo sapiens 491.09 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197272 175444985 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227168 O=C(C[C@@H]1CCCOC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H40N2O4/c30-26(17-21-3-2-16-31-18-21)28-23-8-6-20(7-9-23)10-13-29-14-11-22(12-15-29)24-4-1-5-25-27(24)33-19-32-25/h1,4-5,20-23H,2-3,6-19H2,(H,28,30)/t20-,21-,23-/m0/s1 HZRDMMLAWDPBJF-FUDKSRODSA-N 107539 US8598357, 42 D(2) dopamine receptor Homo sapiens 321.69 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197273 175444986 ZINC96178455 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227169 O=C(C[C@H]1CCCOC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H40N2O4/c30-26(17-21-3-2-16-31-18-21)28-23-8-6-20(7-9-23)10-13-29-14-11-22(12-15-29)24-4-1-5-25-27(24)33-19-32-25/h1,4-5,20-23H,2-3,6-19H2,(H,28,30)/t20-,21-,23-/m1/s1 HZRDMMLAWDPBJF-MQSCRBSSSA-N 107540 US8598357, 43 D(2) dopamine receptor Homo sapiens 408.24 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107540&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197274 175444987 ZINC96178456 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227170 CCOCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H38N2O4/c1-2-29-17-13-24(28)26-21-8-6-19(7-9-21)10-14-27-15-11-20(12-16-27)22-4-3-5-23-25(22)31-18-30-23/h3-5,19-21H,2,6-18H2,1H3,(H,26,28)/t19-,21- YDSLGYGXMJYMOS-XUTJKUGGSA-N 107541 US8598357, 44 D(2) dopamine receptor Homo sapiens 393.12 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197377 175444988 ZINC96178457 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227171 OC1(CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCOc34)CC2)CCC1 InChI=1S/C26H38N2O4/c29-24(17-26(30)12-2-13-26)27-21-7-5-19(6-8-21)9-14-28-15-10-20(11-16-28)22-3-1-4-23-25(22)32-18-31-23/h1,3-4,19-21,30H,2,5-18H2,(H,27,29)/t19-,21- QBQZCKZJIWENBM-XUTJKUGGSA-N 107542 US8598357, 45 D(2) dopamine receptor Homo sapiens 262.23 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107542&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197378 175444989 ZINC96178458 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227172 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C1CCCO1 InChI=1S/C25H36N2O4/c28-25(23-5-2-16-29-23)26-20-8-6-18(7-9-20)10-13-27-14-11-19(12-15-27)21-3-1-4-22-24(21)31-17-30-22/h1,3-4,18-20,23H,2,5-17H2,(H,26,28)/t18-,20-,23? QRDDKCATKOBJNH-VTVZGJJZSA-N 107543 US8598357, 46 D(2) dopamine receptor Homo sapiens 463.70 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197379 175444990 ZINC96178460 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227173 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C1CCOC1 InChI=1S/C25H36N2O4/c28-25(20-11-15-29-16-20)26-21-6-4-18(5-7-21)8-12-27-13-9-19(10-14-27)22-2-1-3-23-24(22)31-17-30-23/h1-3,18-21H,4-17H2,(H,26,28)/t18-,20?,21- ACAWRKNKSILJBW-UVXAETBJSA-N 107544 US8598357, 47 D(2) dopamine receptor Homo sapiens 165.40 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197380 175444991 ZINC96178462 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227174 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C1CCOCC1 InChI=1S/C26H38N2O4/c29-26(21-11-16-30-17-12-21)27-22-6-4-19(5-7-22)8-13-28-14-9-20(10-15-28)23-2-1-3-24-25(23)32-18-31-24/h1-3,19-22H,4-18H2,(H,27,29)/t19-,22- BWSCHPAOVNLCBH-XYWHTSSQSA-N 107545 US8598357, 48 D(2) dopamine receptor Homo sapiens 183.74 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197381 175444992 ZINC96178463 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227175 OC1(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H34N2O4/c27-23(24(28)11-12-24)25-19-6-4-17(5-7-19)8-13-26-14-9-18(10-15-26)20-2-1-3-21-22(20)30-16-29-21/h1-3,17-19,28H,4-16H2,(H,25,27)/t17-,19- OEJHEPOHRGSKLF-UAPYVXQJSA-N 107546 US8598357, 49 D(2) dopamine receptor Homo sapiens 245.32 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197891 175444993 ZINC96178464 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227176 FC(F)(F)C1(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H33F3N2O3/c26-25(27,28)24(11-12-24)23(31)29-19-6-4-17(5-7-19)8-13-30-14-9-18(10-15-30)20-2-1-3-21-22(20)33-16-32-21/h1-3,17-19H,4-16H2,(H,29,31)/t17-,19- GWEQOXQOCNABLR-UAPYVXQJSA-N 107547 US8598357, 50 D(2) dopamine receptor Homo sapiens 245.54 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70656410 175444994 ZINC96178465 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227177 CCC(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H38N2O3/c1-3-18(2)25(28)26-21-9-7-19(8-10-21)11-14-27-15-12-20(13-16-27)22-5-4-6-23-24(22)30-17-29-23/h4-6,18-21H,3,7-17H2,1-2H3,(H,26,28)/t18?,19-,21- LOLIGPMPSPGNGJ-OIFYPAEGSA-N 107548 US8598357, 51 D(2) dopamine receptor Homo sapiens 351.61 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197382 175444995 ZINC96178467 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227178 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C1CCS(=O)(=O)C1 InChI=1S/C25H36N2O5S/c28-25(20-11-15-33(29,30)16-20)26-21-6-4-18(5-7-21)8-12-27-13-9-19(10-14-27)22-2-1-3-23-24(22)32-17-31-23/h1-3,18-21H,4-17H2,(H,26,28)/t18-,20?,21- NXQJYLDOIPIWNN-UVXAETBJSA-N 107549 US8598357, 52 D(2) dopamine receptor Homo sapiens 130.00 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197475 175444996 ZINC96178469 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227179 O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H40N2O4/c30-26(18-21-11-16-31-17-12-21)28-23-6-4-20(5-7-23)8-13-29-14-9-22(10-15-29)24-2-1-3-25-27(24)33-19-32-25/h1-3,20-23H,4-19H2,(H,28,30)/t20-,23- SGABQHZVZUGQTC-JKIUYZKVSA-N 107550 US8598357, 53 D(2) dopamine receptor Homo sapiens 351.77 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197476 175444997 ZINC96178470 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227180 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C1CCC1 InChI=1S/C25H36N2O3/c28-25(20-3-1-4-20)26-21-9-7-18(8-10-21)11-14-27-15-12-19(13-16-27)22-5-2-6-23-24(22)30-17-29-23/h2,5-6,18-21H,1,3-4,7-17H2,(H,26,28)/t18-,21- NBWWBMWMDFWWPB-XGAFWQRZSA-N 107551 US8598357, 54 D(2) dopamine receptor Homo sapiens 100.30 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197477 175444998 ZINC96178471 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227181 CS(=O)(=O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H34N2O5S/c1-31(27,28)15-22(26)24-19-7-5-17(6-8-19)9-12-25-13-10-18(11-14-25)20-3-2-4-21-23(20)30-16-29-21/h2-4,17-19H,5-16H2,1H3,(H,24,26)/t17-,19- FVRSJSBIEQJTRJ-UAPYVXQJSA-N 107552 US8598357, 55 D(2) dopamine receptor Homo sapiens 164.90 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107552&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197478 175444999 ZINC96178472 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227182 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)c1ccc(cc1)N1CCOCC1 InChI=1S/C31H41N3O4/c35-31(25-6-10-27(11-7-25)34-18-20-36-21-19-34)32-26-8-4-23(5-9-26)12-15-33-16-13-24(14-17-33)28-2-1-3-29-30(28)38-22-37-29/h1-3,6-7,10-11,23-24,26H,4-5,8-9,12-22H2,(H,32,35)/t23-,26- BWJOFTXEAUJYMK-OJBMAJLDSA-N 107553 US8598357, 56 D(2) dopamine receptor Homo sapiens 593.34 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107553&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197479 175445000 ZINC96178473 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227183 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)c1ccnc2ccccc12 InChI=1S/C30H35N3O3/c34-30(26-12-16-31-27-6-2-1-4-25(26)27)32-23-10-8-21(9-11-23)13-17-33-18-14-22(15-19-33)24-5-3-7-28-29(24)36-20-35-28/h1-7,12,16,21-23H,8-11,13-15,17-20H2,(H,32,34)/t21-,23- NICPNELNWYJWOA-AFARHQOCSA-N 107554 US8598357, 57 D(2) dopamine receptor Homo sapiens 370.18 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107554&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197566 175445001 ZINC96178474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227184 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)c1ccc2OCCOc2c1 InChI=1S/C29H36N2O5/c32-29(22-6-9-25-27(18-22)34-17-16-33-25)30-23-7-4-20(5-8-23)10-13-31-14-11-21(12-15-31)24-2-1-3-26-28(24)36-19-35-26/h1-3,6,9,18,20-21,23H,4-5,7-8,10-17,19H2,(H,30,32)/t20-,23- RQCOWNFHMUSHMO-JKIUYZKVSA-N 107555 US8598357, 58 D(2) dopamine receptor Homo sapiens 345.34 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107555&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197567 175445002 ZINC96178475 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227185 O=C(Cc1ccc2OCOc2c1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C29H36N2O5/c32-28(17-21-6-9-25-27(16-21)35-18-33-25)30-23-7-4-20(5-8-23)10-13-31-14-11-22(12-15-31)24-2-1-3-26-29(24)36-19-34-26/h1-3,6,9,16,20,22-23H,4-5,7-8,10-15,17-19H2,(H,30,32)/t20-,23- HAMNVKXXPQTQTJ-JKIUYZKVSA-N 107556 US8598357, 59 D(2) dopamine receptor Homo sapiens 324.88 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197569 175445003 ZINC96178476 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227186 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)C1COc2ccccc2C1 InChI=1S/C30H38N2O4/c33-30(24-18-23-4-1-2-6-27(23)34-19-24)31-25-10-8-21(9-11-25)12-15-32-16-13-22(14-17-32)26-5-3-7-28-29(26)36-20-35-28/h1-7,21-22,24-25H,8-20H2,(H,31,33)/t21-,24?,25- YGNIYGXERUDUPC-FERRBWLRSA-N 107557 US8598357, 60 D(2) dopamine receptor Homo sapiens 1047.58 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197568 175445004 ZINC96178478 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227187 CN1CCC(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H41N3O3/c1-29-14-10-22(11-15-29)27(31)28-23-7-5-20(6-8-23)9-16-30-17-12-21(13-18-30)24-3-2-4-25-26(24)33-19-32-25/h2-4,20-23H,5-19H2,1H3,(H,28,31)/t20-,23- FIZAPBXYZQYEQQ-JKIUYZKVSA-N 107558 US8598357, 61 D(2) dopamine receptor Homo sapiens 149.51 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197570 175445005 ZINC96178479 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227188 CC1(COC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H36N2O4/c1-25(15-29-16-25)24(28)26-20-7-5-18(6-8-20)9-12-27-13-10-19(11-14-27)21-3-2-4-22-23(21)31-17-30-22/h2-4,18-20H,5-17H2,1H3,(H,26,28)/t18-,20- BXGMQIUZTIUQRE-KESTWPANSA-N 107559 US8598357, 62 D(2) dopamine receptor Homo sapiens 225.02 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197669 175445006 ZINC96178480 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227189 CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCOc34)CC2)CC1 InChI=1S/C29H44N2O4/c1-33-25-11-7-22(8-12-25)19-28(32)30-24-9-5-21(6-10-24)13-16-31-17-14-23(15-18-31)26-3-2-4-27-29(26)35-20-34-27/h2-4,21-25H,5-20H2,1H3,(H,30,32)/t21-,22-,24-,25- BWPAYVFDIRAIID-ZKHCSVRISA-N 107560 US8598357, 63 D(2) dopamine receptor Homo sapiens 360.81 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197670 175445007 ZINC96178481 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227190 C[C@@H](O)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H34N2O4/c1-16(26)23(27)24-19-7-5-17(6-8-19)9-12-25-13-10-18(11-14-25)20-3-2-4-21-22(20)29-15-28-21/h2-4,16-19,26H,5-15H2,1H3,(H,24,27)/t16-,17-,19-/m1/s1 VYAKZBSIEMCYFQ-ZHALLVOQSA-N 107561 US8598357, 64 D(2) dopamine receptor Homo sapiens 268.44 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197671 175445008 ZINC96178482 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227191 OCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H32N2O4/c25-14-21(26)23-18-6-4-16(5-7-18)8-11-24-12-9-17(10-13-24)19-2-1-3-20-22(19)28-15-27-20/h1-3,16-18,25H,4-15H2,(H,23,26)/t16-,18- PATXYRVWJPYPMG-SAABIXHNSA-N 107562 US8598357, 65 D(2) dopamine receptor Homo sapiens 297.86 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197672 175445009 ZINC96178483 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227192 OC1(CCCCC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H40N2O4/c30-26(27(31)14-2-1-3-15-27)28-22-9-7-20(8-10-22)11-16-29-17-12-21(13-18-29)23-5-4-6-24-25(23)33-19-32-24/h4-6,20-22,31H,1-3,7-19H2,(H,28,30)/t20-,22- IHPMTTUHDSGUHU-AQYVVDRMSA-N 107563 US8598357, 66 D(2) dopamine receptor Homo sapiens 218.85 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197673 175445010 ZINC96178484 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227193 COC1(CCCCC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C28H42N2O4/c1-32-28(15-3-2-4-16-28)27(31)29-23-10-8-21(9-11-23)12-17-30-18-13-22(14-19-30)24-6-5-7-25-26(24)34-20-33-25/h5-7,21-23H,2-4,8-20H2,1H3,(H,29,31)/t21-,23- CNROBRSRSPCLEA-AFARHQOCSA-N 107564 US8598357, 67 D(2) dopamine receptor Homo sapiens 196.50 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197674 175445011 ZINC96178485 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227194 CN1CCN(CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCOc34)CC2)CC1 InChI=1S/C27H42N4O3/c1-29-15-17-31(18-16-29)19-26(32)28-23-7-5-21(6-8-23)9-12-30-13-10-22(11-14-30)24-3-2-4-25-27(24)34-20-33-25/h2-4,21-23H,5-20H2,1H3,(H,28,32)/t21-,23- SGRZMLIEPZAREQ-AFARHQOCSA-N 107565 US8598357, 68 D(2) dopamine receptor Homo sapiens 103.73 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197774 175445012 ZINC96178486 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227195 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C21H32N2O4S/c1-28(24,25)22-18-7-5-16(6-8-18)9-12-23-13-10-17(11-14-23)19-3-2-4-20-21(19)27-15-26-20/h2-4,16-18,22H,5-15H2,1H3/t16-,18- KZZIOGFYAGNURW-SAABIXHNSA-N 107566 US8598357, 69 D(2) dopamine receptor Homo sapiens 413.56 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197775 175445013 ZINC96178487 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227196 O=S(=O)(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)c1ccccc1 InChI=1S/C26H34N2O4S/c29-33(30,23-5-2-1-3-6-23)27-22-11-9-20(10-12-22)13-16-28-17-14-21(15-18-28)24-7-4-8-25-26(24)32-19-31-25/h1-8,20-22,27H,9-19H2/t20-,22- IMVQXSCPSNTRQQ-AQYVVDRMSA-N 107567 US8598357, 70 D(2) dopamine receptor Homo sapiens 63.45 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197776 175445014 ZINC96178488 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227197 Fc1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H33FN2O4S/c27-21-6-10-23(11-7-21)34(30,31)28-22-8-4-19(5-9-22)12-15-29-16-13-20(14-17-29)24-2-1-3-25-26(24)33-18-32-25/h1-3,6-7,10-11,19-20,22,28H,4-5,8-9,12-18H2/t19-,22- IQNJCFSRWWUBAK-XYWHTSSQSA-N 107568 US8598357, 71 D(2) dopamine receptor Homo sapiens 104.22 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197777 175445015 ZINC96178489 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227198 Cn1cnc(c1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H34N4O4S/c1-27-15-23(25-16-27)33(29,30)26-20-7-5-18(6-8-20)9-12-28-13-10-19(11-14-28)21-3-2-4-22-24(21)32-17-31-22/h2-4,15-16,18-20,26H,5-14,17H2,1H3/t18-,20- FOXUYLUURDWAGN-KESTWPANSA-N 107569 US8598357, 72 D(2) dopamine receptor Homo sapiens 114.29 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197778 175445016 ZINC96178490 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227199 FC(F)(F)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H29F3N2O3/c23-22(24,25)21(28)26-17-6-4-15(5-7-17)8-11-27-12-9-16(10-13-27)18-2-1-3-19-20(18)30-14-29-19/h1-3,15-17H,4-14H2,(H,26,28)/t15-,17- ZPNCBCHKBMWQEH-JCNLHEQBSA-N 107570 US8598357, 73 D(2) dopamine receptor Homo sapiens 346.12 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197779 175445017 ZINC96178491 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227200 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)N1CCc2ccccc12 InChI=1S/C29H37N3O3/c33-29(32-19-15-23-4-1-2-6-26(23)32)30-24-10-8-21(9-11-24)12-16-31-17-13-22(14-18-31)25-5-3-7-27-28(25)35-20-34-27/h1-7,21-22,24H,8-20H2,(H,30,33)/t21-,24- QOJAXHPIIVARQJ-SAIGFBBZSA-N 107571 US8598357, 74 D(2) dopamine receptor Homo sapiens 229.19 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197886 175445018 ZINC96178492 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227201 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H35N3O3/c1-25(2)23(27)24-19-8-6-17(7-9-19)10-13-26-14-11-18(12-15-26)20-4-3-5-21-22(20)29-16-28-21/h3-5,17-19H,6-16H2,1-2H3,(H,24,27)/t17-,19- WMLONRUBOXAPOV-UAPYVXQJSA-N 107572 US8598357, 75 D(2) dopamine receptor Homo sapiens 52.74 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197996 175445019 ZINC96178493 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227202 FCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H31FN2O3/c23-14-21(26)24-18-6-4-16(5-7-18)8-11-25-12-9-17(10-13-25)19-2-1-3-20-22(19)28-15-27-20/h1-3,16-18H,4-15H2,(H,24,26)/t16-,18- AICFPAVUBCPJDG-SAABIXHNSA-N 107573 US8598357, 76 D(2) dopamine receptor Homo sapiens 229.70 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197887 175445020 ZINC96178494 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227203 Clc1ccc(NC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCOc34)CC2)cc1 InChI=1S/C27H34ClN3O3/c28-21-6-10-23(11-7-21)30-27(32)29-22-8-4-19(5-9-22)12-15-31-16-13-20(14-17-31)24-2-1-3-25-26(24)34-18-33-25/h1-3,6-7,10-11,19-20,22H,4-5,8-9,12-18H2,(H2,29,30,32)/t19-,22- GLBVEJHGCUMFCU-XYWHTSSQSA-N 107574 US8598357, 77 D(2) dopamine receptor Homo sapiens 2707.02 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197997 175445021 ZINC96178495 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227204 CN(C)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H35N3O4S/c1-24(2)30(26,27)23-19-8-6-17(7-9-19)10-13-25-14-11-18(12-15-25)20-4-3-5-21-22(20)29-16-28-21/h3-5,17-19,23H,6-16H2,1-2H3/t17-,19- RWXAMLMBPWFLTN-UAPYVXQJSA-N 107575 US8598357, 78 D(2) dopamine receptor Homo sapiens 229.21 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197889 175445022 ZINC96178496 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 227205 O=S(=O)(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCOc23)CC1)N1CCOCC1 InChI=1S/C24H37N3O5S/c28-33(29,27-14-16-30-17-15-27)25-21-6-4-19(5-7-21)8-11-26-12-9-20(10-13-26)22-2-1-3-23-24(22)32-18-31-23/h1-3,19-21,25H,4-18H2/t19-,21- VXTKAVNUVLUPMB-XUTJKUGGSA-N 107576 US8598357, 79 D(2) dopamine receptor Homo sapiens 229.43 US Patent 10.7270/Q27P8X2S aid1800181 US8598357 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=107576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=107576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60197888 175445023 ZINC96178497 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250020 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C21H31N3O3/c1-16(25)22-18-7-5-17(6-8-18)9-10-23-11-13-24(14-12-23)19-3-2-4-20-21(19)27-15-26-20/h2-4,17-18H,5-15H2,1H3,(H,22,25)/t17-,18- OMSAEBUIHWCGKQ-IYARVYRRSA-N 121454 US8722683, 1 D(2) dopamine receptor Homo sapiens 67.35 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163405 225147886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250021 COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H35N3O4/c1-28-16-10-22(27)24-19-7-5-18(6-8-19)9-11-25-12-14-26(15-13-25)20-3-2-4-21-23(20)30-17-29-21/h2-4,18-19H,5-17H2,1H3,(H,24,27)/t18-,19- WNRXKNXWFCFUSX-WGSAOQKQSA-N 121455 US8722683, 2 D(2) dopamine receptor Homo sapiens 173.34 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163406 225147887 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250022 O=C(CC1COCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H37N3O5/c29-24(16-21-17-30-14-15-31-21)26-20-6-4-19(5-7-20)8-9-27-10-12-28(13-11-27)22-2-1-3-23-25(22)33-18-32-23/h1-3,19-21H,4-18H2,(H,26,29)/t19-,20-,21? FFHHYAWKMDTAAH-YGQOYYDZSA-N 121456 US8722683, 3 D(2) dopamine receptor Homo sapiens 197.58 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163407 225147888 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250023 O=C(C[C@H]1COCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H37N3O5/c29-24(16-21-17-30-14-15-31-21)26-20-6-4-19(5-7-20)8-9-27-10-12-28(13-11-27)22-2-1-3-23-25(22)33-18-32-23/h1-3,19-21H,4-18H2,(H,26,29)/t19-,20-,21-/m0/s1 FFHHYAWKMDTAAH-ACRUOGEOSA-N 121457 US8722683, 4 D(2) dopamine receptor Homo sapiens 301.03 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163408 225147889 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250024 O=C(C[C@@H]1COCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H37N3O5/c29-24(16-21-17-30-14-15-31-21)26-20-6-4-19(5-7-20)8-9-27-10-12-28(13-11-27)22-2-1-3-23-25(22)33-18-32-23/h1-3,19-21H,4-18H2,(H,26,29)/t19-,20-,21-/m1/s1 FFHHYAWKMDTAAH-NJDAHSKKSA-N 121458 US8722683, 5 D(2) dopamine receptor Homo sapiens 172.17 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163409 225147890 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250025 O=C(CC1CCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H37N3O4/c29-24(17-21-3-2-16-30-21)26-20-8-6-19(7-9-20)10-11-27-12-14-28(15-13-27)22-4-1-5-23-25(22)32-18-31-23/h1,4-5,19-21H,2-3,6-18H2,(H,26,29)/t19-,20-,21? FIMDFCHHYZMXDV-YGQOYYDZSA-N 121459 US8722683, 6 D(2) dopamine receptor Homo sapiens 188.71 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163526 225147891 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250026 CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H33N3O3/c1-2-21(26)23-18-8-6-17(7-9-18)10-11-24-12-14-25(15-13-24)19-4-3-5-20-22(19)28-16-27-20/h3-5,17-18H,2,6-16H2,1H3,(H,23,26)/t17-,18- GZGMMCKOZRMGDA-IYARVYRRSA-N 121460 US8722683, 7 D(2) dopamine receptor Homo sapiens 74.48 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163528 225147892 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250027 O=C(CC1CC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H35N3O3/c28-23(16-19-4-5-19)25-20-8-6-18(7-9-20)10-11-26-12-14-27(15-13-26)21-2-1-3-22-24(21)30-17-29-22/h1-3,18-20H,4-17H2,(H,25,28)/t18-,20- UDDOLORLTBTWLQ-KESTWPANSA-N 121461 US8722683, 8 D(2) dopamine receptor Homo sapiens 141.87 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121461&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163529 225147893 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250028 COCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H33N3O4/c1-27-15-21(26)23-18-7-5-17(6-8-18)9-10-24-11-13-25(14-12-24)19-3-2-4-20-22(19)29-16-28-20/h2-4,17-18H,5-16H2,1H3,(H,23,26)/t17-,18- GIAJRMOZOJKYBH-IYARVYRRSA-N 121462 US8722683, 9 D(2) dopamine receptor Homo sapiens 238.22 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161565 225147894 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250029 OCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C21H31N3O4/c25-14-20(26)22-17-6-4-16(5-7-17)8-9-23-10-12-24(13-11-23)18-2-1-3-19-21(18)28-15-27-19/h1-3,16-17,25H,4-15H2,(H,22,26)/t16-,17- DTTQGOYOJDSYEL-QAQDUYKDSA-N 121463 US8722683, 10 D(2) dopamine receptor Homo sapiens 183.57 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161566 225147895 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250030 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)c1ccccc1 InChI=1S/C26H33N3O3/c30-26(21-5-2-1-3-6-21)27-22-11-9-20(10-12-22)13-14-28-15-17-29(18-16-28)23-7-4-8-24-25(23)32-19-31-24/h1-8,20,22H,9-19H2,(H,27,30)/t20-,22- QKNACGZYHIMKOB-AQYVVDRMSA-N 121464 US8722683, 11 D(2) dopamine receptor Homo sapiens 269.17 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161567 225147896 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250031 COC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C21H31N3O4/c1-26-21(25)22-17-7-5-16(6-8-17)9-10-23-11-13-24(14-12-23)18-3-2-4-19-20(18)28-15-27-19/h2-4,16-17H,5-15H2,1H3,(H,22,25)/t16-,17- VJUBLIXVVNAHIX-QAQDUYKDSA-N 121465 US8722683, 12 D(2) dopamine receptor Homo sapiens 68.55 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161568 225147897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250032 Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)on1 InChI=1S/C25H34N4O4/c1-18-15-21(33-27-18)16-24(30)26-20-7-5-19(6-8-20)9-10-28-11-13-29(14-12-28)22-3-2-4-23-25(22)32-17-31-23/h2-4,15,19-20H,5-14,16-17H2,1H3,(H,26,30)/t19-,20- CMSXGONDQZVASO-MXVIHJGJSA-N 121466 US8722683, 13 D(2) dopamine receptor Homo sapiens 314.12 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161569 225147898 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250033 O=C(CC#N)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H30N4O3/c23-10-8-21(27)24-18-6-4-17(5-7-18)9-11-25-12-14-26(15-13-25)19-2-1-3-20-22(19)29-16-28-20/h1-3,17-18H,4-9,11-16H2,(H,24,27)/t17-,18- FSKDJHMJFCWDOT-IYARVYRRSA-N 121467 US8722683, 14 D(2) dopamine receptor Homo sapiens 75.98 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161691 225147899 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250034 OC1(CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)CCCCC1 InChI=1S/C27H41N3O4/c31-25(19-27(32)12-2-1-3-13-27)28-22-9-7-21(8-10-22)11-14-29-15-17-30(18-16-29)23-5-4-6-24-26(23)34-20-33-24/h4-6,21-22,32H,1-3,7-20H2,(H,28,31)/t21-,22- GKOMEAJANIRHJV-HZCBDIJESA-N 121468 US8722683, 15 D(2) dopamine receptor Homo sapiens 159.74 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161692 225147900 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250035 FC(F)(F)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H30F3N3O3/c23-22(24,25)14-20(29)26-17-6-4-16(5-7-17)8-9-27-10-12-28(13-11-27)18-2-1-3-19-21(18)31-15-30-19/h1-3,16-17H,4-15H2,(H,26,29)/t16-,17- DNKKASLPXCCBTN-QAQDUYKDSA-N 121469 US8722683, 16 D(2) dopamine receptor Homo sapiens 91.22 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161693 225147901 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250036 CC(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H35N3O3/c1-17(2)23(27)24-19-8-6-18(7-9-19)10-11-25-12-14-26(15-13-25)20-4-3-5-21-22(20)29-16-28-21/h3-5,17-19H,6-16H2,1-2H3,(H,24,27)/t18-,19- TUCVLDGVHWFVIS-WGSAOQKQSA-N 121470 US8722683, 17 D(2) dopamine receptor Homo sapiens 136.57 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161694 225147902 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250037 CC(C)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H37N3O3/c1-18(2)16-23(28)25-20-8-6-19(7-9-20)10-11-26-12-14-27(15-13-26)21-4-3-5-22-24(21)30-17-29-22/h3-5,18-20H,6-17H2,1-2H3,(H,25,28)/t19-,20- BWGWYQWYXXYEFW-MXVIHJGJSA-N 121471 US8722683, 18 D(2) dopamine receptor Homo sapiens 132.77 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161695 225147903 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250038 CCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H35N3O3/c1-2-4-22(27)24-19-9-7-18(8-10-19)11-12-25-13-15-26(16-14-25)20-5-3-6-21-23(20)29-17-28-21/h3,5-6,18-19H,2,4,7-17H2,1H3,(H,24,27)/t18-,19- KQLWXCILLOUXJV-WGSAOQKQSA-N 121472 US8722683, 19 D(2) dopamine receptor Homo sapiens 143.65 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161696 225147904 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250039 FC1(F)CC1C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H31F2N3O3/c24-23(25)14-18(23)22(29)26-17-6-4-16(5-7-17)8-9-27-10-12-28(13-11-27)19-2-1-3-20-21(19)31-15-30-20/h1-3,16-18H,4-15H2,(H,26,29)/t16-,17-,18? FNCHOLREEKOGDL-JHJOSGQCSA-N 121473 US8722683, 20 D(2) dopamine receptor Homo sapiens 143.98 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161827 225147905 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250040 COC(C)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H37N3O4/c1-18(29-2)16-23(28)25-20-8-6-19(7-9-20)10-11-26-12-14-27(15-13-26)21-4-3-5-22-24(21)31-17-30-22/h3-5,18-20H,6-17H2,1-2H3,(H,25,28)/t18?,19-,20- MBVXIDMKZKQKDD-JUUMZCOKSA-N 121474 US8722683, 21 D(2) dopamine receptor Homo sapiens 181.28 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161564 225147906 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250041 O=C(CC1COC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H35N3O4/c28-23(14-19-15-29-16-19)25-20-6-4-18(5-7-20)8-9-26-10-12-27(13-11-26)21-2-1-3-22-24(21)31-17-30-22/h1-3,18-20H,4-17H2,(H,25,28)/t18-,20- LJYQDVKZJSSWJS-KESTWPANSA-N 121475 US8722683, 22 D(2) dopamine receptor Homo sapiens 105.93 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163527 225147907 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250042 CO[C@@H]1CC[C@@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)C1 InChI=1S/C27H41N3O4/c1-32-23-10-7-21(17-23)18-26(31)28-22-8-5-20(6-9-22)11-12-29-13-15-30(16-14-29)24-3-2-4-25-27(24)34-19-33-25/h2-4,20-23H,5-19H2,1H3,(H,28,31)/t20-,21-,22-,23-/m1/s1 GQPOGVMYXNWAPK-SSGKUCQKSA-N 121476 US8722683, 23 D(2) dopamine receptor Homo sapiens 182.55 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163525 225147908 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250043 CC(C)(O)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H35N3O4/c1-23(2,28)22(27)24-18-8-6-17(7-9-18)10-11-25-12-14-26(15-13-25)19-4-3-5-20-21(19)30-16-29-20/h3-5,17-18,28H,6-16H2,1-2H3,(H,24,27)/t17-,18- JVGMVZVCYZVQMN-IYARVYRRSA-N 121477 US8722683, 24 D(2) dopamine receptor Homo sapiens 181.01 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121477&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161828 225147909 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250044 CO[C@H](C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H35N3O4/c1-17(28-2)23(27)24-19-8-6-18(7-9-19)10-11-25-12-14-26(15-13-25)20-4-3-5-21-22(20)30-16-29-21/h3-5,17-19H,6-16H2,1-2H3,(H,24,27)/t17-,18-,19-/m1/s1 GRGGMNIWCOHOKK-GUDVDZBRSA-N 121478 US8722683, 25 D(2) dopamine receptor Homo sapiens 250.3 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121478&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161830 225147910 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250045 CO[C@@H](C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H35N3O4/c1-17(28-2)23(27)24-19-8-6-18(7-9-19)10-11-25-12-14-26(15-13-25)20-4-3-5-21-22(20)30-16-29-21/h3-5,17-19H,6-16H2,1-2H3,(H,24,27)/t17-,18-,19-/m0/s1 GRGGMNIWCOHOKK-FHWLQOOXSA-N 121479 US8722683, 26 D(2) dopamine receptor Homo sapiens 150.42 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161829 225147911 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250046 CC(C)(O)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H37N3O4/c1-24(2,29)16-22(28)25-19-8-6-18(7-9-19)10-11-26-12-14-27(15-13-26)20-4-3-5-21-23(20)31-17-30-21/h3-5,18-19,29H,6-17H2,1-2H3,(H,25,28)/t18-,19- RWYJJIZNTJVITE-WGSAOQKQSA-N 121480 US8722683, 27 D(2) dopamine receptor Homo sapiens 76.78 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161831 225147912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250047 OC1(CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)CCC1 InChI=1S/C25H37N3O4/c29-23(17-25(30)10-2-11-25)26-20-7-5-19(6-8-20)9-12-27-13-15-28(16-14-27)21-3-1-4-22-24(21)32-18-31-22/h1,3-4,19-20,30H,2,5-18H2,(H,26,29)/t19-,20- ALLUIYWATYVDFM-MXVIHJGJSA-N 121481 US8722683, 28 D(2) dopamine receptor Homo sapiens 94.57 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121481&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161961 225147913 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250048 OC1(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H33N3O4/c27-22(23(28)9-10-23)24-18-6-4-17(5-7-18)8-11-25-12-14-26(15-13-25)19-2-1-3-20-21(19)30-16-29-20/h1-3,17-18,28H,4-16H2,(H,24,27)/t17-,18- ITNZRVAWAMTRJC-IYARVYRRSA-N 121482 US8722683, 29 D(2) dopamine receptor Homo sapiens 61.45 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121482&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161832 225147914 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250049 O=C(C[C@@H]1CCCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H39N3O4/c30-25(18-22-4-1-2-17-31-22)27-21-9-7-20(8-10-21)11-12-28-13-15-29(16-14-28)23-5-3-6-24-26(23)33-19-32-24/h3,5-6,20-22H,1-2,4,7-19H2,(H,27,30)/t20-,21-,22-/m0/s1 SGAVDPALLQJHPW-FKBYEOEOSA-N 121483 US8722683, 30 D(2) dopamine receptor Homo sapiens 219.64 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161962 225147915 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250050 O=C(C[C@H]1CCCCO1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H39N3O4/c30-25(18-22-4-1-2-17-31-22)27-21-9-7-20(8-10-21)11-12-28-13-15-29(16-14-28)23-5-3-6-24-26(23)33-19-32-24/h3,5-6,20-22H,1-2,4,7-19H2,(H,27,30)/t20-,21-,22-/m1/s1 SGAVDPALLQJHPW-YPAWHYETSA-N 121484 US8722683, 31 D(2) dopamine receptor Homo sapiens 310.25 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161963 225147916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250051 O=C(C[C@@H]1CCCOC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H39N3O4/c30-25(17-21-3-2-16-31-18-21)27-22-8-6-20(7-9-22)10-11-28-12-14-29(15-13-28)23-4-1-5-24-26(23)33-19-32-24/h1,4-5,20-22H,2-3,6-19H2,(H,27,30)/t20-,21-,22-/m0/s1 UIWGASRGCHQVHR-FKBYEOEOSA-N 121485 US8722683, 32 D(2) dopamine receptor Homo sapiens 136.98 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121485&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161965 225147917 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250052 O=C(C[C@H]1CCCOC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H39N3O4/c30-25(17-21-3-2-16-31-18-21)27-22-8-6-20(7-9-22)10-11-28-12-14-29(15-13-28)23-4-1-5-24-26(23)33-19-32-24/h1,4-5,20-22H,2-3,6-19H2,(H,27,30)/t20-,21-,22-/m1/s1 UIWGASRGCHQVHR-YPAWHYETSA-N 121486 US8722683, 33 D(2) dopamine receptor Homo sapiens 183.73 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161966 225147918 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250053 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C20H31N3O4S/c1-28(24,25)21-17-7-5-16(6-8-17)9-10-22-11-13-23(14-12-22)18-3-2-4-19-20(18)27-15-26-19/h2-4,16-17,21H,5-15H2,1H3/t16-,17- VSYGMBWVAURWIK-QAQDUYKDSA-N 121487 US8722683, 34 D(2) dopamine receptor Homo sapiens 145.23 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121487&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60161964 225147919 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250054 OC1(CCC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H35N3O4/c28-23(24(29)10-2-11-24)25-19-7-5-18(6-8-19)9-12-26-13-15-27(16-14-26)20-3-1-4-21-22(20)31-17-30-21/h1,3-4,18-19,29H,2,5-17H2,(H,25,28)/t18-,19- SNZRMVSWDNWUOY-WGSAOQKQSA-N 121488 US8722683, 35 D(2) dopamine receptor Homo sapiens 84.94 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162098 225147920 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250055 OC1(CCCC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H37N3O4/c29-24(25(30)11-1-2-12-25)26-20-8-6-19(7-9-20)10-13-27-14-16-28(17-15-27)21-4-3-5-22-23(21)32-18-31-22/h3-5,19-20,30H,1-2,6-18H2,(H,26,29)/t19-,20- DKNAYNJDTLBNCH-MXVIHJGJSA-N 121489 US8722683, 36 D(2) dopamine receptor Homo sapiens 123.97 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162099 225147921 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250056 OC1(CCCCC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H39N3O4/c30-25(26(31)12-2-1-3-13-26)27-21-9-7-20(8-10-21)11-14-28-15-17-29(18-16-28)22-5-4-6-23-24(22)33-19-32-23/h4-6,20-21,31H,1-3,7-19H2,(H,27,30)/t20-,21- SJPCWOAPBGZFOQ-MEMLXQNLSA-N 121490 US8722683, 37 D(2) dopamine receptor Homo sapiens 175.4 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121490&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162100 225147922 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250057 CCC(O)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H35N3O4/c1-2-20(27)23(28)24-18-8-6-17(7-9-18)10-11-25-12-14-26(15-13-25)19-4-3-5-21-22(19)30-16-29-21/h3-5,17-18,20,27H,2,6-16H2,1H3,(H,24,28)/t17-,18-,20? FYSQMYZWYIPETJ-RSBROLRWSA-N 121491 US8722683, 38 D(2) dopamine receptor Homo sapiens 122.13 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162101 225147923 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250058 CC(C)[C@@H](O)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H37N3O4/c1-17(2)22(28)24(29)25-19-8-6-18(7-9-19)10-11-26-12-14-27(15-13-26)20-4-3-5-21-23(20)31-16-30-21/h3-5,17-19,22,28H,6-16H2,1-2H3,(H,25,29)/t18-,19-,22-/m1/s1 AAPCMUAAQFZHRZ-WOIUINJBSA-N 121492 US8722683, 39 D(2) dopamine receptor Homo sapiens 90.15 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162102 225147924 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250059 CC(C)[C@H](O)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H37N3O4/c1-17(2)22(28)24(29)25-19-8-6-18(7-9-19)10-11-26-12-14-27(15-13-26)20-4-3-5-21-23(20)31-16-30-21/h3-5,17-19,22,28H,6-16H2,1-2H3,(H,25,29)/t18-,19-,22-/m0/s1 AAPCMUAAQFZHRZ-IPJJNNNSSA-N 121493 US8722683, 40 D(2) dopamine receptor Homo sapiens 73.41 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162103 225147925 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250060 COC1(CCCCC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C27H41N3O4/c1-32-27(13-3-2-4-14-27)26(31)28-22-10-8-21(9-11-22)12-15-29-16-18-30(19-17-29)23-6-5-7-24-25(23)34-20-33-24/h5-7,21-22H,2-4,8-20H2,1H3,(H,28,31)/t21-,22- OXHDXVWUJBSFBE-HZCBDIJESA-N 121494 US8722683, 41 D(2) dopamine receptor Homo sapiens 250.97 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121494&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162225 225147926 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250061 C[C@@H](O)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H33N3O4/c1-16(26)22(27)23-18-7-5-17(6-8-18)9-10-24-11-13-25(14-12-24)19-3-2-4-20-21(19)29-15-28-20/h2-4,16-18,26H,5-15H2,1H3,(H,23,27)/t16-,17-,18-/m1/s1 QIUIRCOXERNMCI-KZNAEPCWSA-N 121495 US8722683, 42 D(2) dopamine receptor Homo sapiens 89.81 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162618 225147927 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250062 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)C1CCOCC1 InChI=1S/C25H37N3O4/c29-25(20-9-16-30-17-10-20)26-21-6-4-19(5-7-21)8-11-27-12-14-28(15-13-27)22-2-1-3-23-24(22)32-18-31-23/h1-3,19-21H,4-18H2,(H,26,29)/t19-,21- FUJBVUPRADYUIB-XUTJKUGGSA-N 121496 US8722683, 43 D(2) dopamine receptor Homo sapiens 218.89 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121496&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162226 225147928 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250063 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)C1CCCO1 InChI=1S/C24H35N3O4/c28-24(22-5-2-16-29-22)25-19-8-6-18(7-9-19)10-11-26-12-14-27(15-13-26)20-3-1-4-21-23(20)31-17-30-21/h1,3-4,18-19,22H,2,5-17H2,(H,25,28)/t18-,19-,22? GHIPMMXQJHAVMI-DDDLIOIYSA-N 121497 US8722683, 44 D(2) dopamine receptor Homo sapiens 116.64 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162227 225147929 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250064 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)c1ccc(cc1)N1CCOCC1 InChI=1S/C30H40N4O4/c35-30(24-6-10-26(11-7-24)33-18-20-36-21-19-33)31-25-8-4-23(5-9-25)12-13-32-14-16-34(17-15-32)27-2-1-3-28-29(27)38-22-37-28/h1-3,6-7,10-11,23,25H,4-5,8-9,12-22H2,(H,31,35)/t23-,25- ZDOKZVOMQRCQDR-ALOJWSFFSA-N 121498 US8722683, 45 D(2) dopamine receptor Homo sapiens 1510.24 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162229 225147930 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250065 Fc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H32FN3O3/c27-21-8-6-20(7-9-21)26(31)28-22-10-4-19(5-11-22)12-13-29-14-16-30(17-15-29)23-2-1-3-24-25(23)33-18-32-24/h1-3,6-9,19,22H,4-5,10-18H2,(H,28,31)/t19-,22- ZTNICFPCCSHZEL-XYWHTSSQSA-N 121499 US8722683, 46 D(2) dopamine receptor Homo sapiens 82.51 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162358 225147931 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250066 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)c1ccnc2ccccc12 InChI=1S/C29H34N4O3/c34-29(24-12-14-30-25-5-2-1-4-23(24)25)31-22-10-8-21(9-11-22)13-15-32-16-18-33(19-17-32)26-6-3-7-27-28(26)36-20-35-27/h1-7,12,14,21-22H,8-11,13,15-20H2,(H,31,34)/t21-,22- JOHIGOPVFHBKPR-HZCBDIJESA-N 121500 US8722683, 47 D(2) dopamine receptor Homo sapiens 509.13 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162359 225147932 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250067 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)c1cccnc1 InChI=1S/C25H32N4O3/c30-25(20-3-2-11-26-17-20)27-21-8-6-19(7-9-21)10-12-28-13-15-29(16-14-28)22-4-1-5-23-24(22)32-18-31-23/h1-5,11,17,19,21H,6-10,12-16,18H2,(H,27,30)/t19-,21- FGHYITFFCUFQHL-XUTJKUGGSA-N 121501 US8722683, 48 D(2) dopamine receptor Homo sapiens 88.19 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162360 225147933 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250068 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)c1ccc2OCCOc2c1 InChI=1S/C28H35N3O5/c32-28(21-6-9-24-26(18-21)34-17-16-33-24)29-22-7-4-20(5-8-22)10-11-30-12-14-31(15-13-30)23-2-1-3-25-27(23)36-19-35-25/h1-3,6,9,18,20,22H,4-5,7-8,10-17,19H2,(H,29,32)/t20-,22- UGYOAOPLCYFDLB-AQYVVDRMSA-N 121502 US8722683, 49 D(2) dopamine receptor Homo sapiens 4818.65 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162361 225147934 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250069 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)C1COc2ccccc2C1 InChI=1S/C29H37N3O4/c33-29(23-18-22-4-1-2-6-26(22)34-19-23)30-24-10-8-21(9-11-24)12-13-31-14-16-32(17-15-31)25-5-3-7-27-28(25)36-20-35-27/h1-7,21,23-24H,8-20H2,(H,30,33)/t21-,23?,24- BEVNTRQRKQFZTA-UCWUDVSLSA-N 121503 US8722683, 50 D(2) dopamine receptor Homo sapiens 572.43 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60148600 225147935 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250070 O=C(Cc1ccc2OCOc2c1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C28H35N3O5/c32-27(17-21-6-9-24-26(16-21)35-18-33-24)29-22-7-4-20(5-8-22)10-11-30-12-14-31(15-13-30)23-2-1-3-25-28(23)36-19-34-25/h1-3,6,9,16,20,22H,4-5,7-8,10-15,17-19H2,(H,29,32)/t20-,22- UPKMERWQQHPRMB-AQYVVDRMSA-N 121504 US8722683, 51 D(2) dopamine receptor Homo sapiens 680.96 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162362 225147936 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250071 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)C1CCS(=O)(=O)C1 InChI=1S/C24H35N3O5S/c28-24(19-9-15-33(29,30)16-19)25-20-6-4-18(5-7-20)8-10-26-11-13-27(14-12-26)21-2-1-3-22-23(21)32-17-31-22/h1-3,18-20H,4-17H2,(H,25,28)/t18-,19?,20- XNKJYDSSCQLJQZ-UQTQIZBZSA-N 121505 US8722683, 52 D(2) dopamine receptor Homo sapiens 58.95 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162750 225147937 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250072 O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H39N3O4/c30-25(18-21-9-16-31-17-10-21)27-22-6-4-20(5-7-22)8-11-28-12-14-29(15-13-28)23-2-1-3-24-26(23)33-19-32-24/h1-3,20-22H,4-19H2,(H,27,30)/t20-,22- XYOCQKZCBWVHNF-AQYVVDRMSA-N 121506 US8722683, 53 D(2) dopamine receptor Homo sapiens 138.86 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162228 225147938 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250073 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)C1CCC1 InChI=1S/C24H35N3O3/c28-24(19-3-1-4-19)25-20-9-7-18(8-10-20)11-12-26-13-15-27(16-14-26)21-5-2-6-22-23(21)30-17-29-22/h2,5-6,18-20H,1,3-4,7-17H2,(H,25,28)/t18-,20- CVLYSHSUQHJMJF-KESTWPANSA-N 121507 US8722683, 54 D(2) dopamine receptor Homo sapiens 91.14 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121507&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162488 225147939 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250074 CS(=O)(=O)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H33N3O5S/c1-31(27,28)15-21(26)23-18-7-5-17(6-8-18)9-10-24-11-13-25(14-12-24)19-3-2-4-20-22(19)30-16-29-20/h2-4,17-18H,5-16H2,1H3,(H,23,26)/t17-,18- LZICIBCEISDAND-IYARVYRRSA-N 121508 US8722683, 55 D(2) dopamine receptor Homo sapiens 95.38 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162489 225147940 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250075 CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)CC1 InChI=1S/C28H43N3O4/c1-33-24-11-7-22(8-12-24)19-27(32)29-23-9-5-21(6-10-23)13-14-30-15-17-31(18-16-30)25-3-2-4-26-28(25)35-20-34-26/h2-4,21-24H,5-20H2,1H3,(H,29,32)/t21-,22-,23-,24- KOVMYLKRTMAELX-ZWGSZDQZSA-N 121509 US8722683, 56 D(2) dopamine receptor Homo sapiens 752.51 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162617 225147941 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 252914 Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccc(cc3)-c3cccc(=O)[nH]3)CC2)c1Cl InChI=1S/C26H26Cl2N4O2/c27-21-5-3-7-23(25(21)28)32-17-15-31(16-18-32)14-2-1-13-29-26(34)20-11-9-19(10-12-20)22-6-4-8-24(33)30-22/h1-12H,13-18H2,(H,29,34)(H,30,33)/b2-1+ GTRAXVNCZVAHOO-OWOJBTEDSA-N 50219117 CHEMBL244562::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-trans-but-2-enyl)-4-(6-oxo-1,6-dihydropyridin-2-yl)benzamide::US8748608, 9 D(2) dopamine receptor Homo sapiens 41 37.00 C US Patent 10.7270/Q2GT5KVC aid1800502 US8748608 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J The United States of America as Represented by the Secretary of the Department of Health and Human Services http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219117&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44427820 104092487 CHEMBL244562 ZINC28711319 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 252915 Cc1cccc(n1)-c1ccc(cc1)C(=O)NC\C=C\CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C27H28Cl2N4O/c1-20-6-4-8-24(31-20)21-10-12-22(13-11-21)27(34)30-14-2-3-15-32-16-18-33(19-17-32)25-9-5-7-23(28)26(25)29/h2-13H,14-19H2,1H3,(H,30,34)/b3-2+ IEANVAFYLZJSPC-NSCUHMNNSA-N 50219102 CHEMBL398175::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-trans-but-2-enyl)-4-(6-methylpyridin-2-yl)benzamide::US8748608, 10 D(2) dopamine receptor Homo sapiens 1300 37.00 C US Patent 10.7270/Q2GT5KVC aid1800502 US8748608 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J The United States of America as Represented by the Secretary of the Department of Health and Human Services http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219102&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44427821 104092472 CHEMBL398175 ZINC28711320 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 252916 Cc1cccnc1-c1ccc(cc1)C(=O)NC\C=C\CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C27H28Cl2N4O/c1-20-6-5-14-30-26(20)21-9-11-22(12-10-21)27(34)31-13-2-3-15-32-16-18-33(19-17-32)24-8-4-7-23(28)25(24)29/h2-12,14H,13,15-19H2,1H3,(H,31,34)/b3-2+ MTJYJBYKMIGLMS-NSCUHMNNSA-N 50219114 CHEMBL244773::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-trans-but-2-enyl)-4-(3-methylpyridin-2-yl)benzamide::US8748608, 11 D(2) dopamine receptor Homo sapiens 368 37.00 C US Patent 10.7270/Q2GT5KVC aid1800502 US8748608 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J The United States of America as Represented by the Secretary of the Department of Health and Human Services http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219114&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44427822 104092484 CHEMBL244773 ZINC28711321 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 252917 O[N]1=C(C=CC=C1)c1ccc(cc1)C(=O)NC\C=C\CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C26H27Cl2N4O2/c27-22-6-5-8-24(25(22)28)31-18-16-30(17-19-31)14-4-2-13-29-26(33)21-11-9-20(10-12-21)23-7-1-3-15-32(23)34/h1-12,15,34H,13-14,16-19H2,(H,29,33)/b4-2+ VMYURVKSBQZGQS-DUXPYHPUSA-N 123840 US8748608, 12 D(2) dopamine receptor Homo sapiens 22.9 37.00 C US Patent 10.7270/Q2GT5KVC aid1800502 US8748608 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J The United States of America as Represented by the Secretary of the Department of Health and Human Services http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123840&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 59543955 225150246 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 252918 COc1ccccc1N1CCN(C\C=C\CNC(=O)c2ccc(cc2)-c2ccccn2)CC1 InChI=1S/C27H30N4O2/c1-33-26-10-3-2-9-25(26)31-20-18-30(19-21-31)17-7-6-16-29-27(32)23-13-11-22(12-14-23)24-8-4-5-15-28-24/h2-15H,16-21H2,1H3,(H,29,32)/b7-6+ UCNUZCBZAAKMDU-VOTSOKGWSA-N 50219107 CHEMBL394541::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-trans-but-2-enyl)-4-pyridin-2-ylbenzamide::US8748608, 14 D(2) dopamine receptor Homo sapiens 175 37.00 C US Patent 10.7270/Q2GT5KVC aid1800502 US8748608 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J The United States of America as Represented by the Secretary of the Department of Health and Human Services http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44427825 104092477 CHEMBL394541 ZINC28711324 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 252919 COc1ccccc1N1CCN(C\C=C\CNC(=O)c2ccc-3c(Cc4ccccc-34)c2)CC1 InChI=1S/C29H31N3O2/c1-34-28-11-5-4-10-27(28)32-18-16-31(17-19-32)15-7-6-14-30-29(33)23-12-13-26-24(21-23)20-22-8-2-3-9-25(22)26/h2-13,21H,14-20H2,1H3,(H,30,33)/b7-6+ UUYDEYACQFNFMI-VOTSOKGWSA-N 50219113 CHEMBL244989::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-trans-but-2-enyl)-9H-fluorene-2-carboxamide::US8748608, 15 D(2) dopamine receptor Homo sapiens 179 37.00 C US Patent 10.7270/Q2GT5KVC aid1800502 US8748608 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J The United States of America as Represented by the Secretary of the Department of Health and Human Services http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219113&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44427826 104092483 CHEMBL244989 ZINC28711325 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 252920 OC(CCNC(=O)c1ccc(cc1)-c1ccccn1)CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C26H28Cl2N4O2/c27-22-4-3-6-24(25(22)28)32-16-14-31(15-17-32)18-21(33)11-13-30-26(34)20-9-7-19(8-10-20)23-5-1-2-12-29-23/h1-10,12,21,33H,11,13-18H2,(H,30,34) JTJUCUMXKUPFBQ-UHFFFAOYSA-N 123842 US8748608, 16 D(2) dopamine receptor Homo sapiens 15.8 37.00 C US Patent 10.7270/Q2GT5KVC aid1800502 US8748608 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J The United States of America as Represented by the Secretary of the Department of Health and Human Services http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44427827 225150248 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 252921 OC(CCN1CCN(CC1)c1cccc(Cl)c1Cl)CNC(=O)c1ccc(cc1)-c1ccccn1 InChI=1S/C26H28Cl2N4O2/c27-22-4-3-6-24(25(22)28)32-16-14-31(15-17-32)13-11-21(33)18-30-26(34)20-9-7-19(8-10-20)23-5-1-2-12-29-23/h1-10,12,21,33H,11,13-18H2,(H,30,34) ZQBFPGSJRSEUAX-UHFFFAOYSA-N 123847 US8748608, 21 D(2) dopamine receptor Homo sapiens 88.3 37.00 C US Patent 10.7270/Q2GT5KVC aid1800502 US8748608 Newman, AH; Grundt, P; Cyriac, GC; Luedtke, R; Cao, J The United States of America as Represented by the Secretary of the Department of Health and Human Services http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44427836 225150253 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250076 CN1CCC(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C26H40N4O3/c1-28-12-10-21(11-13-28)26(31)27-22-7-5-20(6-8-22)9-14-29-15-17-30(18-16-29)23-3-2-4-24-25(23)33-19-32-24/h2-4,20-22H,5-19H2,1H3,(H,27,31)/t20-,22- DAUWLWXYAUUDKU-AQYVVDRMSA-N 121510 US8722683, 57 D(2) dopamine receptor Homo sapiens 62.94 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162490 225147942 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250077 CC1(COC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H35N3O4/c1-24(15-29-16-24)23(28)25-19-7-5-18(6-8-19)9-10-26-11-13-27(14-12-26)20-3-2-4-21-22(20)31-17-30-21/h2-4,18-19H,5-17H2,1H3,(H,25,28)/t18-,19- RGOWASQQDQKEKM-WGSAOQKQSA-N 121511 US8722683, 58 D(2) dopamine receptor Homo sapiens 81.08 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162491 225147943 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250078 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)c1ccc(cc1)C#N InChI=1S/C27H32N4O3/c28-18-21-4-8-22(9-5-21)27(32)29-23-10-6-20(7-11-23)12-13-30-14-16-31(17-15-30)24-2-1-3-25-26(24)34-19-33-25/h1-5,8-9,20,23H,6-7,10-17,19H2,(H,29,32)/t20-,23- JHONYJKBTVQFJZ-JKIUYZKVSA-N 121512 US8722683, 59 D(2) dopamine receptor Homo sapiens 101.02 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162492 225147944 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250079 ClC1CC(C1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H34ClN3O3/c25-19-14-18(15-19)24(29)26-20-6-4-17(5-7-20)8-9-27-10-12-28(13-11-27)21-2-1-3-22-23(21)31-16-30-22/h1-3,17-20H,4-16H2,(H,26,29)/t17-,18?,19?,20- GUGMHFQRQQBWKY-YUNKUFCWSA-N 121513 US8722683, 60 D(2) dopamine receptor Homo sapiens 81.06 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162616 225147945 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250080 CN1CCN(CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)CC1 InChI=1S/C26H41N5O3/c1-28-11-13-30(14-12-28)19-25(32)27-22-7-5-21(6-8-22)9-10-29-15-17-31(18-16-29)23-3-2-4-24-26(23)34-20-33-24/h2-4,21-22H,5-20H2,1H3,(H,27,32)/t21-,22- YPNBJNLSFKYUJW-HZCBDIJESA-N 121514 US8722683, 61 D(2) dopamine receptor Homo sapiens 38.06 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162493 225147946 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250081 COC1(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H35N3O4/c1-29-24(10-11-24)23(28)25-19-7-5-18(6-8-19)9-12-26-13-15-27(16-14-26)20-3-2-4-21-22(20)31-17-30-21/h2-4,18-19H,5-17H2,1H3,(H,25,28)/t18-,19- BWMBSQXAENBLPV-WGSAOQKQSA-N 121515 US8722683, 62 D(2) dopamine receptor Homo sapiens 86.54 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162619 225147947 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250082 COC(C)(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C24H37N3O4/c1-24(2,29-3)23(28)25-19-9-7-18(8-10-19)11-12-26-13-15-27(16-14-26)20-5-4-6-21-22(20)31-17-30-21/h4-6,18-19H,7-17H2,1-3H3,(H,25,28)/t18-,19- RHBIYVUWPQXJFC-WGSAOQKQSA-N 121516 US8722683, 63 D(2) dopamine receptor Homo sapiens 116.62 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162620 225147948 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250083 CO[C@H](C(C)C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H39N3O4/c1-18(2)23(30-3)25(29)26-20-9-7-19(8-10-20)11-12-27-13-15-28(16-14-27)21-5-4-6-22-24(21)32-17-31-22/h4-6,18-20,23H,7-17H2,1-3H3,(H,26,29)/t19-,20-,23-/m1/s1 IWGVABNVNOQFPY-TXTKFYIRSA-N 121517 US8722683, 64 D(2) dopamine receptor Homo sapiens 89.5 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162621 225147949 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250084 CO[C@@H](C(C)C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H39N3O4/c1-18(2)23(30-3)25(29)26-20-9-7-19(8-10-20)11-12-27-13-15-28(16-14-27)21-5-4-6-22-24(21)32-17-31-22/h4-6,18-20,23H,7-17H2,1-3H3,(H,26,29)/t19-,20-,23-/m0/s1 IWGVABNVNOQFPY-JTAQYXEDSA-N 121518 US8722683, 65 D(2) dopamine receptor Homo sapiens 111.52 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162751 225147950 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250085 FC(F)(F)CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C21H30F3N3O4S/c22-21(23,24)14-32(28,29)25-17-6-4-16(5-7-17)8-9-26-10-12-27(13-11-26)18-2-1-3-19-20(18)31-15-30-19/h1-3,16-17,25H,4-15H2/t16-,17- FIQUQIIUSBAECI-QAQDUYKDSA-N 121519 US8722683, 66 D(2) dopamine receptor Homo sapiens 73.84 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162753 225147951 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250086 O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)c1ccccc1 InChI=1S/C25H33N3O4S/c29-33(30,22-5-2-1-3-6-22)26-21-11-9-20(10-12-21)13-14-27-15-17-28(18-16-27)23-7-4-8-24-25(23)32-19-31-24/h1-8,20-21,26H,9-19H2/t20-,21- PWGOIITXHIWDRA-MEMLXQNLSA-N 121520 US8722683, 67 D(2) dopamine receptor Homo sapiens 72.43 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162883 225147952 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250087 Fc1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C25H32FN3O4S/c26-20-6-10-22(11-7-20)34(30,31)27-21-8-4-19(5-9-21)12-13-28-14-16-29(17-15-28)23-2-1-3-24-25(23)33-18-32-24/h1-3,6-7,10-11,19,21,27H,4-5,8-9,12-18H2/t19-,21- AVHWSQKJWQBOIR-XUTJKUGGSA-N 121521 US8722683, 68 D(2) dopamine receptor Homo sapiens 46.18 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162752 225147953 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250088 Cn1cnc(c1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C23H33N5O4S/c1-26-15-22(24-16-26)33(29,30)25-19-7-5-18(6-8-19)9-10-27-11-13-28(14-12-27)20-3-2-4-21-23(20)32-17-31-21/h2-4,15-16,18-19,25H,5-14,17H2,1H3/t18-,19- BYGFRAXTFHIMHT-WGSAOQKQSA-N 121522 US8722683, 69 D(2) dopamine receptor Homo sapiens 55.32 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162754 225147954 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250089 FC(F)(F)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C21H28F3N3O3/c22-21(23,24)20(28)25-16-6-4-15(5-7-16)8-9-26-10-12-27(13-11-26)17-2-1-3-18-19(17)30-14-29-18/h1-3,15-16H,4-14H2,(H,25,28)/t15-,16- QMOLKOODFFHIEC-WKILWMFISA-N 121523 US8722683, 70 D(2) dopamine receptor Homo sapiens 113.43 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121523&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162884 225147955 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250090 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)N1CCc2ccccc12 InChI=1S/C28H36N4O3/c33-28(32-15-13-22-4-1-2-5-24(22)32)29-23-10-8-21(9-11-23)12-14-30-16-18-31(19-17-30)25-6-3-7-26-27(25)35-20-34-26/h1-7,21,23H,8-20H2,(H,29,33)/t21-,23- XIGLRHPWOZXGTP-AFARHQOCSA-N 121524 US8722683, 71 D(2) dopamine receptor Homo sapiens 241.28 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121524&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162885 225147956 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250091 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C22H34N4O3/c1-24(2)22(27)23-18-8-6-17(7-9-18)10-11-25-12-14-26(15-13-25)19-4-3-5-20-21(19)29-16-28-20/h3-5,17-18H,6-16H2,1-2H3,(H,23,27)/t17-,18- UIERZYNYMSMAJC-IYARVYRRSA-N 121525 US8722683, 72 D(2) dopamine receptor Homo sapiens 30.42 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163148 225147957 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250092 FCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C21H30FN3O3/c22-14-20(26)23-17-6-4-16(5-7-17)8-9-24-10-12-25(13-11-24)18-2-1-3-19-21(18)28-15-27-19/h1-3,16-17H,4-15H2,(H,23,26)/t16-,17- OOBJUMKQKXVZFD-QAQDUYKDSA-N 121526 US8722683, 73 D(2) dopamine receptor Homo sapiens 123.11 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162886 225147958 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250093 OC[C@H]1C[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)C1 InChI=1S/C26H39N3O4/c30-17-21-14-20(15-21)16-25(31)27-22-6-4-19(5-7-22)8-9-28-10-12-29(13-11-28)23-2-1-3-24-26(23)33-18-32-24/h1-3,19-22,30H,4-18H2,(H,27,31)/t19-,20-,21-,22- QURJJYMBLXNGPW-CHDDOINTSA-N 121527 US8722683, 74 D(2) dopamine receptor Homo sapiens 116.67 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162888 225147959 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250094 Clc1ccc(NC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)cc1 InChI=1S/C26H33ClN4O3/c27-20-6-10-22(11-7-20)29-26(32)28-21-8-4-19(5-9-21)12-13-30-14-16-31(17-15-30)23-2-1-3-24-25(23)34-18-33-24/h1-3,6-7,10-11,19,21H,4-5,8-9,12-18H2,(H2,28,29,32)/t19-,21- NZKGNAIACSEITE-XUTJKUGGSA-N 121528 US8722683, 75 D(2) dopamine receptor Homo sapiens 157.94 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163149 225147960 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250095 CN(C)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 InChI=1S/C21H34N4O4S/c1-23(2)30(26,27)22-18-8-6-17(7-9-18)10-11-24-12-14-25(15-13-24)19-4-3-5-20-21(19)29-16-28-20/h3-5,17-18,22H,6-16H2,1-2H3/t17-,18- PLVMBXJAZDNOCA-IYARVYRRSA-N 121529 US8722683, 76 D(2) dopamine receptor Homo sapiens 127.71 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121529&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60162887 225147961 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 250096 O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)N1CCOCC1 InChI=1S/C23H36N4O5S/c28-33(29,27-14-16-30-17-15-27)24-20-6-4-19(5-7-20)8-9-25-10-12-26(13-11-25)21-2-1-3-22-23(21)32-18-31-22/h1-3,19-20,24H,4-18H2/t19-,20- XLIMTGZUFAEKLX-MXVIHJGJSA-N 121530 US8722683, 77 D(2) dopamine receptor Homo sapiens 62.99 US Patent 10.7270/Q2J101VJ aid1800455 US8722683 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=121530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=121530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60163013 225147962 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272339 CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3occc23)CC1 InChI=1S/C23H32N2O2/c1-17(26)24-20-7-5-18(6-8-20)9-13-25-14-10-19(11-15-25)21-3-2-4-23-22(21)12-16-27-23/h2-4,12,16,18-20H,5-11,13-15H2,1H3,(H,24,26)/t18-,20- JQMOQEGMADHTMB-KESTWPANSA-N 138397 US8877778, 1 D(2) dopamine receptor Homo sapiens 186.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386961 249815622 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272340 COCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3occc23)CC1 InChI=1S/C25H36N2O3/c1-29-17-13-25(28)26-21-7-5-19(6-8-21)9-14-27-15-10-20(11-16-27)22-3-2-4-24-23(22)12-18-30-24/h2-4,12,18-21H,5-11,13-17H2,1H3,(H,26,28)/t19-,21- ZJUHEDMNUHRHQM-XUTJKUGGSA-N 138398 US8877778, 2 D(2) dopamine receptor Homo sapiens 287.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387208 249815623 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272341 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3occc23)CC1)C1CCOCC1 InChI=1S/C27H38N2O3/c30-27(22-11-17-31-18-12-22)28-23-6-4-20(5-7-23)8-14-29-15-9-21(10-16-29)24-2-1-3-26-25(24)13-19-32-26/h1-3,13,19-23H,4-12,14-18H2,(H,28,30)/t20-,23- MFAOTUDCDBJKBZ-JKIUYZKVSA-N 138399 US8877778, 3 D(2) dopamine receptor Homo sapiens 305 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138399&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387209 249815624 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272342 O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3occc23)CC1 InChI=1S/C28H40N2O3/c31-28(20-22-11-17-32-18-12-22)29-24-6-4-21(5-7-24)8-14-30-15-9-23(10-16-30)25-2-1-3-27-26(25)13-19-33-27/h1-3,13,19,21-24H,4-12,14-18,20H2,(H,29,31)/t21-,24- SMYZAAOKKUETMB-SAIGFBBZSA-N 138400 US8877778, 4 D(2) dopamine receptor Homo sapiens 218.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138400&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387210 249815625 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272343 CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C23H34N2O2/c1-17(26)24-20-7-5-18(6-8-20)9-13-25-14-10-19(11-15-25)21-3-2-4-23-22(21)12-16-27-23/h2-4,18-20H,5-16H2,1H3,(H,24,26)/t18-,20- HOFXBWNODSOCNI-KESTWPANSA-N 138401 US8877778, 5 D(2) dopamine receptor Homo sapiens 297.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138401&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387211 249815626 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272344 COCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C25H38N2O3/c1-29-17-13-25(28)26-21-7-5-19(6-8-21)9-14-27-15-10-20(11-16-27)22-3-2-4-24-23(22)12-18-30-24/h2-4,19-21H,5-18H2,1H3,(H,26,28)/t19-,21- DDOIPTNOPZXSRC-XUTJKUGGSA-N 138402 US8877778, 6 D(2) dopamine receptor Homo sapiens 509.4 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138402&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387212 249815627 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 273616 Clc1cccc(N2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-20-4-3-5-21(22(20)25)28-13-11-27(12-14-28)10-1-2-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h3-7,16H,1-2,8-15H2,(H,26,29) VBFRZHYHMOZIEU-UHFFFAOYSA-N 50395582 CHEMBL2165133::UNC10000004::US9156822, 25 D(2) dopamine receptor Homo sapiens 12 US Patent 10.7270/Q28K77RC US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599145 163344606 CHEMBL2165133 ZINC95552743 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 273617 Clc1cccc(N2CCN(CCCCOc3ccc4cn[nH]c4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-18-4-3-5-20(21(18)23)27-11-9-26(10-12-27)8-1-2-13-28-17-7-6-16-15-24-25-19(16)14-17/h3-7,14-15H,1-2,8-13H2,(H,24,25) IKOXHMZXTCWMQE-UHFFFAOYSA-N 50395581 CHEMBL2165134::UNC10000010::US9156822, 28 D(2) dopamine receptor Homo sapiens 18 US Patent 10.7270/Q28K77RC US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597091 163344605 CHEMBL2165134 ZINC95552916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 273618 Clc1cccc(N2CCN(Cc3ccc(Oc4ccc5CCC(=O)Nc5c4)cc3)CC2)c1Cl InChI=1S/C26H25Cl2N3O2/c27-22-2-1-3-24(26(22)28)31-14-12-30(13-15-31)17-18-4-8-20(9-5-18)33-21-10-6-19-7-11-25(32)29-23(19)16-21/h1-6,8-10,16H,7,11-15,17H2,(H,29,32) MCIWPVPYVLZFFO-UHFFFAOYSA-N 50395583 CHEMBL2165132::UNC10099973::US9156822, 31 D(2) dopamine receptor Homo sapiens 16 US Patent 10.7270/Q28K77RC US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559507 163344607 CHEMBL2165132 ZINC95556448 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 273619 Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C20H22Cl2N4O2/c21-15-3-1-4-18(19(15)22)26-10-8-25(9-11-26)7-2-12-28-14-5-6-16-17(13-14)24-20(27)23-16/h1,3-6,13H,2,7-12H2,(H2,23,24,27) NKDQNOFCLUVBIY-UHFFFAOYSA-N 185693 UNC10099988::US9156822, 34 D(2) dopamine receptor Homo sapiens 36 US Patent 10.7270/Q28K77RC US8598119 Mates, S; Fienberg, A; Wennogle, L Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225824 315516384 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272345 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)C1CCOCC1 InChI=1S/C27H40N2O3/c30-27(22-11-17-31-18-12-22)28-23-6-4-20(5-7-23)8-14-29-15-9-21(10-16-29)24-2-1-3-26-25(24)13-19-32-26/h1-3,20-23H,4-19H2,(H,28,30)/t20-,23- XOPDSATVNGEEAY-JKIUYZKVSA-N 138403 US8877778, 7 D(2) dopamine receptor Homo sapiens 716.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138403&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387213 249815628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272346 O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C28H42N2O3/c31-28(20-22-11-17-32-18-12-22)29-24-6-4-21(5-7-24)8-14-30-15-9-23(10-16-30)25-2-1-3-27-26(25)13-19-33-27/h1-3,21-24H,4-20H2,(H,29,31)/t21-,24- YRIPLGKCIYJQGV-SAIGFBBZSA-N 138404 US8877778, 8 D(2) dopamine receptor Homo sapiens 650 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138404&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387459 249815629 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272347 CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3occc23)CC1 InChI=1S/C24H34N2O2/c1-2-24(27)25-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)21-4-3-5-23-22(21)13-17-28-23/h3-5,13,17-20H,2,6-12,14-16H2,1H3,(H,25,27)/t18-,20- BFHHRFYYBLXMIN-KESTWPANSA-N 138405 US8877778, 9 D(2) dopamine receptor Homo sapiens 91.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138405&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57379033 249815630 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272348 COCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3occc23)CC1 InChI=1S/C24H34N2O3/c1-28-17-24(27)25-20-7-5-18(6-8-20)9-13-26-14-10-19(11-15-26)21-3-2-4-23-22(21)12-16-29-23/h2-4,12,16,18-20H,5-11,13-15,17H2,1H3,(H,25,27)/t18-,20- YNSPDEYTWHJYJV-KESTWPANSA-N 138406 US8877778, 10 D(2) dopamine receptor Homo sapiens 256.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138406&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387460 249815631 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272349 CS(=O)(=O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3occc23)CC1 InChI=1S/C24H34N2O4S/c1-31(28,29)17-24(27)25-20-7-5-18(6-8-20)9-13-26-14-10-19(11-15-26)21-3-2-4-23-22(21)12-16-30-23/h2-4,12,16,18-20H,5-11,13-15,17H2,1H3,(H,25,27)/t18-,20- BQGJUXXCNWSZIZ-KESTWPANSA-N 138407 US8877778, 11 D(2) dopamine receptor Homo sapiens 153.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138407&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387461 249815632 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272350 O=C(CC1COCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3occc23)CC1 InChI=1S/C27H38N2O4/c30-27(18-23-19-31-16-17-32-23)28-22-6-4-20(5-7-22)8-12-29-13-9-21(10-14-29)24-2-1-3-26-25(24)11-15-33-26/h1-3,11,15,20-23H,4-10,12-14,16-19H2,(H,28,30)/t20-,22-,23? IDLCGPWMKHMBHA-YEMPIKNUSA-N 138408 US8877778, 12 D(2) dopamine receptor Homo sapiens 219 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138408&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387462 249815633 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272351 CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C24H36N2O2/c1-2-24(27)25-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)21-4-3-5-23-22(21)13-17-28-23/h3-5,18-20H,2,6-17H2,1H3,(H,25,27)/t18-,20- LTYAWIKNOPSPBV-KESTWPANSA-N 138409 US8877778, 13 D(2) dopamine receptor Homo sapiens 345.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138409&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387463 249815634 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272352 COCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C24H36N2O3/c1-28-17-24(27)25-20-7-5-18(6-8-20)9-13-26-14-10-19(11-15-26)21-3-2-4-23-22(21)12-16-29-23/h2-4,18-20H,5-17H2,1H3,(H,25,27)/t18-,20- PPBAFHRXACXAFW-KESTWPANSA-N 138410 US8877778, 14 D(2) dopamine receptor Homo sapiens 671.2 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138410&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387696 249815635 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272353 CS(=O)(=O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C24H36N2O4S/c1-31(28,29)17-24(27)25-20-7-5-18(6-8-20)9-13-26-14-10-19(11-15-26)21-3-2-4-23-22(21)12-16-30-23/h2-4,18-20H,5-17H2,1H3,(H,25,27)/t18-,20- LIRAXYPAXGDSQL-KESTWPANSA-N 138411 US8877778, 15 D(2) dopamine receptor Homo sapiens 418.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138411&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387697 249815636 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272354 O=C(CC1COCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H40N2O4/c30-27(18-23-19-31-16-17-32-23)28-22-6-4-20(5-7-22)8-12-29-13-9-21(10-14-29)24-2-1-3-26-25(24)11-15-33-26/h1-3,20-23H,4-19H2,(H,28,30)/t20-,22-,23? RMGLEYGDPBYQMA-YEMPIKNUSA-N 138412 US8877778, 16 D(2) dopamine receptor Homo sapiens 729 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138412&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387698 249815637 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272355 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccccc1 InChI=1S/C28H36N2O2/c31-28(23-5-2-1-3-6-23)29-24-11-9-21(10-12-24)13-17-30-18-14-22(15-19-30)25-7-4-8-27-26(25)16-20-32-27/h1-8,21-22,24H,9-20H2,(H,29,31)/t21-,24- KTKVHSSURNTWLF-SAIGFBBZSA-N 138413 US8877778, 17 D(2) dopamine receptor Homo sapiens 318.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138413&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387699 249815638 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272356 FC(F)(F)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C24H33F3N2O2/c25-24(26,27)16-23(30)28-19-6-4-17(5-7-19)8-12-29-13-9-18(10-14-29)20-2-1-3-22-21(20)11-15-31-22/h1-3,17-19H,4-16H2,(H,28,30)/t17-,19- XLYRRJFZVKDMFE-UAPYVXQJSA-N 138414 US8877778, 18 D(2) dopamine receptor Homo sapiens 344.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138414&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387700 249815639 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272357 Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCCc34)CC2)on1 InChI=1S/C27H37N3O3/c1-19-17-23(33-29-19)18-27(31)28-22-7-5-20(6-8-22)9-13-30-14-10-21(11-15-30)24-3-2-4-26-25(24)12-16-32-26/h2-4,17,20-22H,5-16,18H2,1H3,(H,28,31)/t20-,22- SUYNNRLZQGBZKP-AQYVVDRMSA-N 138415 US8877778, 19 D(2) dopamine receptor Homo sapiens 540 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138415&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387701 249815640 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272358 OCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C23H34N2O3/c26-16-23(27)24-19-6-4-17(5-7-19)8-12-25-13-9-18(10-14-25)20-2-1-3-22-21(20)11-15-28-22/h1-3,17-19,26H,4-16H2,(H,24,27)/t17-,19- FJTBQZNFUHLCOQ-UAPYVXQJSA-N 138416 US8877778, 20 D(2) dopamine receptor Homo sapiens 570.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138416&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387923 249815641 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272359 O=C(C[C@@H]1COCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H40N2O4/c30-27(18-23-19-31-16-17-32-23)28-22-6-4-20(5-7-22)8-12-29-13-9-21(10-14-29)24-2-1-3-26-25(24)11-15-33-26/h1-3,20-23H,4-19H2,(H,28,30)/t20-,22-,23-/m1/s1 RMGLEYGDPBYQMA-YMPZKCBVSA-N 138417 US8877778, 21 D(2) dopamine receptor Homo sapiens 420.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138417&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387924 249815642 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272360 O=C(C[C@H]1COCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H40N2O4/c30-27(18-23-19-31-16-17-32-23)28-22-6-4-20(5-7-22)8-12-29-13-9-21(10-14-29)24-2-1-3-26-25(24)11-15-33-26/h1-3,20-23H,4-19H2,(H,28,30)/t20-,22-,23-/m0/s1 RMGLEYGDPBYQMA-PMVMPFDFSA-N 138418 US8877778, 22 D(2) dopamine receptor Homo sapiens 687.4 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387925 249815643 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272361 CC(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C25H38N2O2/c1-18(2)25(28)26-21-8-6-19(7-9-21)10-14-27-15-11-20(12-16-27)22-4-3-5-24-23(22)13-17-29-24/h3-5,18-21H,6-17H2,1-2H3,(H,26,28)/t19-,21- RDUVGAYRQBFLOT-XUTJKUGGSA-N 138419 US8877778, 23 D(2) dopamine receptor Homo sapiens 285 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387926 249815644 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272362 CC(C)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H40N2O2/c1-19(2)18-26(29)27-22-8-6-20(7-9-22)10-14-28-15-11-21(12-16-28)23-4-3-5-25-24(23)13-17-30-25/h3-5,19-22H,6-18H2,1-2H3,(H,27,29)/t20-,22- CNRWQWXTVCUGCK-AQYVVDRMSA-N 138420 US8877778, 24 D(2) dopamine receptor Homo sapiens 212.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138420&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387927 249815645 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272363 O=C(CC1CCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H40N2O3/c30-27(19-23-3-2-17-31-23)28-22-8-6-20(7-9-22)10-14-29-15-11-21(12-16-29)24-4-1-5-26-25(24)13-18-32-26/h1,4-5,20-23H,2-3,6-19H2,(H,28,30)/t20-,22-,23? OOQJGWPOJZCKHM-YEMPIKNUSA-N 138421 US8877778, 25 D(2) dopamine receptor Homo sapiens 379.2 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387928 249815646 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272364 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)C1CCC1 InChI=1S/C26H38N2O2/c29-26(21-3-1-4-21)27-22-9-7-19(8-10-22)11-15-28-16-12-20(13-17-28)23-5-2-6-25-24(23)14-18-30-25/h2,5-6,19-22H,1,3-4,7-18H2,(H,27,29)/t19-,22- QNJDOVDHWZTXIL-XYWHTSSQSA-N 138422 US8877778, 26 D(2) dopamine receptor Homo sapiens 144.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384158 249815647 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272365 OCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C24H36N2O3/c27-16-11-24(28)25-20-6-4-18(5-7-20)8-13-26-14-9-19(10-15-26)21-2-1-3-23-22(21)12-17-29-23/h1-3,18-20,27H,4-17H2,(H,25,28)/t18-,20- YFJPHIULVVJFIS-KESTWPANSA-N 138423 US8877778, 27 D(2) dopamine receptor Homo sapiens 344.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138423&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384159 249815648 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272366 OC1(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C25H36N2O3/c28-24(25(29)12-13-25)26-20-6-4-18(5-7-20)8-14-27-15-9-19(10-16-27)21-2-1-3-23-22(21)11-17-30-23/h1-3,18-20,29H,4-17H2,(H,26,28)/t18-,20- QGGUMCZIAASPSU-KESTWPANSA-N 138424 US8877778, 28 D(2) dopamine receptor Homo sapiens 298.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138424&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384160 249815649 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272367 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)C1CC1 InChI=1S/C25H36N2O2/c28-25(20-6-7-20)26-21-8-4-18(5-9-21)10-14-27-15-11-19(12-16-27)22-2-1-3-24-23(22)13-17-29-24/h1-3,18-21H,4-17H2,(H,26,28)/t18-,21- AYPVCAPOVVHYNK-XGAFWQRZSA-N 138425 US8877778, 29 D(2) dopamine receptor Homo sapiens 151.4 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138425&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384161 249815650 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272368 O=C(CC1CC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H38N2O2/c29-26(18-20-4-5-20)27-22-8-6-19(7-9-22)10-14-28-15-11-21(12-16-28)23-2-1-3-25-24(23)13-17-30-25/h1-3,19-22H,4-18H2,(H,27,29)/t19-,22- GUKSVDQGXPESAC-XYWHTSSQSA-N 138426 US8877778, 30 D(2) dopamine receptor Homo sapiens 267.5 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138426&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384162 249815651 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272369 O=C(C[C@H]1CCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H40N2O3/c30-27(19-23-3-2-17-31-23)28-22-8-6-20(7-9-22)10-14-29-15-11-21(12-16-29)24-4-1-5-26-25(24)13-18-32-26/h1,4-5,20-23H,2-3,6-19H2,(H,28,30)/t20-,22-,23-/m1/s1 OOQJGWPOJZCKHM-YMPZKCBVSA-N 138427 US8877778, 31 D(2) dopamine receptor Homo sapiens 514.1 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384163 249815652 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272370 O=C(C[C@@H]1CCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H40N2O3/c30-27(19-23-3-2-17-31-23)28-22-8-6-20(7-9-22)10-14-29-15-11-21(12-16-29)24-4-1-5-26-25(24)13-18-32-26/h1,4-5,20-23H,2-3,6-19H2,(H,28,30)/t20-,22-,23-/m0/s1 OOQJGWPOJZCKHM-PMVMPFDFSA-N 138428 US8877778, 32 D(2) dopamine receptor Homo sapiens 557.4 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384394 249815653 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272371 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(cc1)N1CCOCC1 InChI=1S/C32H43N3O3/c36-32(26-6-10-28(11-7-26)35-19-22-37-23-20-35)33-27-8-4-24(5-9-27)12-16-34-17-13-25(14-18-34)29-2-1-3-31-30(29)15-21-38-31/h1-3,6-7,10-11,24-25,27H,4-5,8-9,12-23H2,(H,33,36)/t24-,27- FSMFABUIPFMXCD-HNKWHGCMSA-N 138429 US8877778, 33 D(2) dopamine receptor Homo sapiens 128.1 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384395 249815654 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272372 Clc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C28H35ClN2O2/c29-23-8-6-22(7-9-23)28(32)30-24-10-4-20(5-11-24)12-16-31-17-13-21(14-18-31)25-2-1-3-27-26(25)15-19-33-27/h1-3,6-9,20-21,24H,4-5,10-19H2,(H,30,32)/t20-,24- HZIPKQNESFBOQW-LSNLESRRSA-N 138430 US8877778, 34 D(2) dopamine receptor Homo sapiens 71.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384396 249815655 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272373 Fc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C28H35FN2O2/c29-23-8-6-22(7-9-23)28(32)30-24-10-4-20(5-11-24)12-16-31-17-13-21(14-18-31)25-2-1-3-27-26(25)15-19-33-27/h1-3,6-9,20-21,24H,4-5,10-19H2,(H,30,32)/t20-,24- PUFRXIARUMGNAR-LSNLESRRSA-N 138431 US8877778, 35 D(2) dopamine receptor Homo sapiens 73.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384397 249815656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272374 O[C@H](CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)C(F)(F)F InChI=1S/C25H35F3N2O3/c26-25(27,28)23(31)16-24(32)29-19-6-4-17(5-7-19)8-12-30-13-9-18(10-14-30)20-2-1-3-22-21(20)11-15-33-22/h1-3,17-19,23,31H,4-16H2,(H,29,32)/t17-,19-,23-/m1/s1 IGLZWQUSQYHTJF-LYHRCORUSA-N 138432 US8877778, 36 D(2) dopamine receptor Homo sapiens 239.4 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384398 249815657 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272375 OC(C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)C(F)(F)F InChI=1S/C24H33F3N2O3/c25-24(26,27)22(30)23(31)28-18-6-4-16(5-7-18)8-12-29-13-9-17(10-14-29)19-2-1-3-21-20(19)11-15-32-21/h1-3,16-18,22,30H,4-15H2,(H,28,31)/t16-,18-,22? YXGIYSCRDTWJRJ-MYKGNVCDSA-N 138433 US8877778, 37 D(2) dopamine receptor Homo sapiens 240.5 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384668 249815658 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272376 CC(C)(O)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C25H38N2O3/c1-25(2,29)24(28)26-20-8-6-18(7-9-20)10-14-27-15-11-19(12-16-27)21-4-3-5-23-22(21)13-17-30-23/h3-5,18-20,29H,6-17H2,1-2H3,(H,26,28)/t18-,20- HYGWSJJGGPMNNN-KESTWPANSA-N 138434 US8877778, 38 D(2) dopamine receptor Homo sapiens 495.1 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384669 249815659 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272377 OC1(CCC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H38N2O3/c29-25(26(30)13-2-14-26)27-21-7-5-19(6-8-21)9-15-28-16-10-20(11-17-28)22-3-1-4-24-23(22)12-18-31-24/h1,3-4,19-21,30H,2,5-18H2,(H,27,29)/t19-,21- JCOIGYVGPKMQRM-XUTJKUGGSA-N 138435 US8877778, 39 D(2) dopamine receptor Homo sapiens 305.5 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384670 249815660 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272378 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccnc2ccccc12 InChI=1S/C31H37N3O2/c35-31(28-12-17-32-29-6-2-1-4-26(28)29)33-24-10-8-22(9-11-24)13-18-34-19-14-23(15-20-34)25-5-3-7-30-27(25)16-21-36-30/h1-7,12,17,22-24H,8-11,13-16,18-21H2,(H,33,35)/t22-,24- NHOFKPNSQTXBJO-HCGLCNNCSA-N 138436 US8877778, 40 D(2) dopamine receptor Homo sapiens 563 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67972282 249815661 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272379 Cc1cc(on1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H35N3O3/c1-18-17-25(32-28-18)26(30)27-21-7-5-19(6-8-21)9-13-29-14-10-20(11-15-29)22-3-2-4-24-23(22)12-16-31-24/h2-4,17,19-21H,5-16H2,1H3,(H,27,30)/t19-,21- PSQWBHXNCLXCGM-XUTJKUGGSA-N 138437 US8877778, 41 D(2) dopamine receptor Homo sapiens 124.1 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384672 249815662 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272380 Cc1ccc(cn1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C28H37N3O2/c1-20-5-8-23(19-29-20)28(32)30-24-9-6-21(7-10-24)11-15-31-16-12-22(13-17-31)25-3-2-4-27-26(25)14-18-33-27/h2-5,8,19,21-22,24H,6-7,9-18H2,1H3,(H,30,32)/t21-,24- HHAWPWAQIRBXKW-SAIGFBBZSA-N 138438 US8877778, 42 D(2) dopamine receptor Homo sapiens 151 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384673 249815663 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272381 FC(F)(F)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C23H31F3N2O2/c24-23(25,26)22(29)27-18-6-4-16(5-7-18)8-12-28-13-9-17(10-14-28)19-2-1-3-21-20(19)11-15-30-21/h1-3,16-18H,4-15H2,(H,27,29)/t16-,18- KMJHJQFJPSDYJD-SAABIXHNSA-N 138439 US8877778, 43 D(2) dopamine receptor Homo sapiens 288.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384928 249815664 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272382 CN1CCN(CC1)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C33H46N4O2/c1-35-20-22-37(23-21-35)29-11-7-27(8-12-29)33(38)34-28-9-5-25(6-10-28)13-17-36-18-14-26(15-19-36)30-3-2-4-32-31(30)16-24-39-32/h2-4,7-8,11-12,25-26,28H,5-6,9-10,13-24H2,1H3,(H,34,38)/t25-,28- NIASBGFPTRNZRV-FCMXBYMOSA-N 138440 US8877778, 44 D(2) dopamine receptor Homo sapiens 147.1 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384929 249815665 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272383 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(cc1)C#N InChI=1S/C29H35N3O2/c30-20-22-4-8-24(9-5-22)29(33)31-25-10-6-21(7-11-25)12-16-32-17-13-23(14-18-32)26-2-1-3-28-27(26)15-19-34-28/h1-5,8-9,21,23,25H,6-7,10-19H2,(H,31,33)/t21-,25- CLAPZYAXBKPPSX-OKDASEJXSA-N 138441 US8877778, 45 D(2) dopamine receptor Homo sapiens 191.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384930 249815666 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272384 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(nc1)N1CCOCC1 InChI=1S/C31H42N4O3/c36-31(25-6-9-30(32-22-25)35-17-20-37-21-18-35)33-26-7-4-23(5-8-26)10-14-34-15-11-24(12-16-34)27-2-1-3-29-28(27)13-19-38-29/h1-3,6,9,22-24,26H,4-5,7-8,10-21H2,(H,33,36)/t23-,26- FHOVKJHMUHGSDG-OJBMAJLDSA-N 138442 US8877778, 46 D(2) dopamine receptor Homo sapiens 919.5 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67972145 249815667 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272385 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C22H34N2O3S/c1-28(25,26)23-19-7-5-17(6-8-19)9-13-24-14-10-18(11-15-24)20-3-2-4-22-21(20)12-16-27-22/h2-4,17-19,23H,5-16H2,1H3/t17-,19- FOSYKSVEHLEJMK-UAPYVXQJSA-N 138443 US8877778, 47 D(2) dopamine receptor Homo sapiens 328.2 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384932 249815668 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272386 CCS(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C23H36N2O3S/c1-2-29(26,27)24-20-8-6-18(7-9-20)10-14-25-15-11-19(12-16-25)21-4-3-5-23-22(21)13-17-28-23/h3-5,18-20,24H,2,6-17H2,1H3/t18-,20- DMXFLQZSXCIUTO-KESTWPANSA-N 138444 US8877778, 48 D(2) dopamine receptor Homo sapiens 333 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384933 249815669 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272387 O=S(=O)(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccccc1 InChI=1S/C27H36N2O3S/c30-33(31,24-5-2-1-3-6-24)28-23-11-9-21(10-12-23)13-17-29-18-14-22(15-19-29)25-7-4-8-27-26(25)16-20-32-27/h1-8,21-23,28H,9-20H2/t21-,23- OPHBHUMUNHDPAE-AFARHQOCSA-N 138445 US8877778, 49 D(2) dopamine receptor Homo sapiens 137.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385168 249815670 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272388 Fc1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H35FN2O3S/c28-22-6-10-24(11-7-22)34(31,32)29-23-8-4-20(5-9-23)12-16-30-17-13-21(14-18-30)25-2-1-3-27-26(25)15-19-33-27/h1-3,6-7,10-11,20-21,23,29H,4-5,8-9,12-19H2/t20-,23- LARFMQZWGLKYLH-JKIUYZKVSA-N 138446 US8877778, 50 D(2) dopamine receptor Homo sapiens 104.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385169 249815671 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272389 CN(C)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C23H37N3O3S/c1-25(2)30(27,28)24-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)21-4-3-5-23-22(21)13-17-29-23/h3-5,18-20,24H,6-17H2,1-2H3/t18-,20- KXPJEGNVGVZNGX-KESTWPANSA-N 138447 US8877778, 51 D(2) dopamine receptor Homo sapiens 250.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67972657 249815672 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272390 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)C1CCOC1 InChI=1S/C26H38N2O3/c29-26(21-11-16-30-18-21)27-22-6-4-19(5-7-22)8-13-28-14-9-20(10-15-28)23-2-1-3-25-24(23)12-17-31-25/h1-3,19-22H,4-18H2,(H,27,29)/t19-,21?,22- GSEFGWJFHUAOCL-CTTUZFCVSA-N 138448 US8877778, 52 D(2) dopamine receptor Homo sapiens 135 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385171 249815673 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272391 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)C1CCCO1 InChI=1S/C26H38N2O3/c29-26(25-5-2-17-30-25)27-21-8-6-19(7-9-21)10-14-28-15-11-20(12-16-28)22-3-1-4-24-23(22)13-18-31-24/h1,3-4,19-21,25H,2,5-18H2,(H,27,29)/t19-,21-,25? GHYRDLJRGXMERZ-RKTRBERCSA-N 138449 US8877778, 53 D(2) dopamine receptor Homo sapiens 372.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385172 249815674 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272392 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)C1CCCOC1 InChI=1S/C27H40N2O3/c30-27(22-3-2-17-31-19-22)28-23-8-6-20(7-9-23)10-14-29-15-11-21(12-16-29)24-4-1-5-26-25(24)13-18-32-26/h1,4-5,20-23H,2-3,6-19H2,(H,28,30)/t20-,22?,23- NKIKKVIRCFKCOG-FXCIWXGGSA-N 138450 US8877778, 54 D(2) dopamine receptor Homo sapiens 633 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385173 249815675 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272393 O=C(CC#N)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C24H33N3O2/c25-13-8-24(28)26-20-6-4-18(5-7-20)9-14-27-15-10-19(11-16-27)21-2-1-3-23-22(21)12-17-29-23/h1-3,18-20H,4-12,14-17H2,(H,26,28)/t18-,20- FJKZYFQWHOCWIZ-KESTWPANSA-N 138451 US8877778, 55 D(2) dopamine receptor Homo sapiens 139.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385423 249815676 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272394 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(cc1)N1CCCCC1 InChI=1S/C33H45N3O2/c37-33(27-9-13-29(14-10-27)36-19-2-1-3-20-36)34-28-11-7-25(8-12-28)15-21-35-22-16-26(17-23-35)30-5-4-6-32-31(30)18-24-38-32/h4-6,9-10,13-14,25-26,28H,1-3,7-8,11-12,15-24H2,(H,34,37)/t25-,28- QTJSAQYKJMJAHN-FCMXBYMOSA-N 138452 US8877778, 56 D(2) dopamine receptor Homo sapiens 2272.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138452&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385424 249815677 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272395 FC(F)(F)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C29H35F3N2O2/c30-29(31,32)23-8-6-22(7-9-23)28(35)33-24-10-4-20(5-11-24)12-16-34-17-13-21(14-18-34)25-2-1-3-27-26(25)15-19-36-27/h1-3,6-9,20-21,24H,4-5,10-19H2,(H,33,35)/t20-,24- JGUXYQFTEZNNTK-LSNLESRRSA-N 138453 US8877778, 57 D(2) dopamine receptor Homo sapiens 1461.2 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385425 249815678 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272396 CC(C)(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H40N2O2/c1-26(2,3)25(29)27-21-9-7-19(8-10-21)11-15-28-16-12-20(13-17-28)22-5-4-6-24-23(22)14-18-30-24/h4-6,19-21H,7-18H2,1-3H3,(H,27,29)/t19-,21- BFIOLCNMADQXRL-XUTJKUGGSA-N 138454 US8877778, 58 D(2) dopamine receptor Homo sapiens 377.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385426 249815679 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272397 CC(C)(C)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H42N2O2/c1-27(2,3)19-26(30)28-22-9-7-20(8-10-22)11-15-29-16-12-21(13-17-29)23-5-4-6-25-24(23)14-18-31-25/h4-6,20-22H,7-19H2,1-3H3,(H,28,30)/t20-,22- SUBVUQDWHHIJCY-AQYVVDRMSA-N 138455 US8877778, 59 D(2) dopamine receptor Homo sapiens 394.4 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385427 249815680 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272398 O=C(CC1CCC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H40N2O2/c30-27(19-21-3-1-4-21)28-23-9-7-20(8-10-23)11-15-29-16-12-22(13-17-29)24-5-2-6-26-25(24)14-18-31-26/h2,5-6,20-23H,1,3-4,7-19H2,(H,28,30)/t20-,23- AWTSHTNAYPKBLJ-JKIUYZKVSA-N 138456 US8877778, 60 D(2) dopamine receptor Homo sapiens 301.2 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385428 249815681 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272399 FC1(F)CC1C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C25H34F2N2O2/c26-25(27)16-22(25)24(30)28-19-6-4-17(5-7-19)8-12-29-13-9-18(10-14-29)20-2-1-3-23-21(20)11-15-31-23/h1-3,17-19,22H,4-16H2,(H,28,30)/t17-,19-,22? FDBMIKAQORBNLT-NRCGHCQOSA-N 138457 US8877778, 61 D(2) dopamine receptor Homo sapiens 235.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385672 249815682 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272400 CCC(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H40N2O2/c1-3-19(2)26(29)27-22-9-7-20(8-10-22)11-15-28-16-12-21(13-17-28)23-5-4-6-25-24(23)14-18-30-25/h4-6,19-22H,3,7-18H2,1-2H3,(H,27,29)/t19?,20-,22- ZOJYMCBGKBJTGD-RVZUZXSLSA-N 138458 US8877778, 62 D(2) dopamine receptor Homo sapiens 1201.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385673 249815683 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272401 CN(C)C(=O)CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H41N3O3/c1-29(2)27(32)11-10-26(31)28-22-8-6-20(7-9-22)12-16-30-17-13-21(14-18-30)23-4-3-5-25-24(23)15-19-33-25/h3-5,20-22H,6-19H2,1-2H3,(H,28,31)/t20-,22- GXRRIZYXGPLXKK-AQYVVDRMSA-N 138459 US8877778, 63 D(2) dopamine receptor Homo sapiens 1063.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385674 249815684 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272402 CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2ccc(F)c3occc23)CC1 InChI=1S/C23H31FN2O2/c1-16(27)25-19-4-2-17(3-5-19)8-12-26-13-9-18(10-14-26)20-6-7-22(24)23-21(20)11-15-28-23/h6-7,11,15,17-19H,2-5,8-10,12-14H2,1H3,(H,25,27)/t17-,19- SUATVGXCTNKNQW-UAPYVXQJSA-N 138460 US8877778, 64 D(2) dopamine receptor Homo sapiens 403.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385675 249815685 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272403 Fc1ccc(C2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCOCC3)CC2)c2ccoc12 InChI=1S/C27H37FN2O3/c28-25-6-5-23(24-12-18-33-26(24)25)20-8-14-30(15-9-20)13-7-19-1-3-22(4-2-19)29-27(31)21-10-16-32-17-11-21/h5-6,12,18-22H,1-4,7-11,13-17H2,(H,29,31)/t19-,22- UQYZSEJGPCJXFW-XYWHTSSQSA-N 138461 US8877778, 65 D(2) dopamine receptor Homo sapiens 361.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138461&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385676 249815686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272404 Fc1ccc(C2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)CC3CCOCC3)CC2)c2ccoc12 InChI=1S/C28H39FN2O3/c29-26-6-5-24(25-12-18-34-28(25)26)22-8-14-31(15-9-22)13-7-20-1-3-23(4-2-20)30-27(32)19-21-10-16-33-17-11-21/h5-6,12,18,20-23H,1-4,7-11,13-17,19H2,(H,30,32)/t20-,23- PYXPRMLVOWMRMK-JKIUYZKVSA-N 138462 US8877778, 66 D(2) dopamine receptor Homo sapiens 615.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385677 249815687 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272405 COCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2ccc(F)c3occc23)CC1 InChI=1S/C25H35FN2O3/c1-30-16-12-24(29)27-20-4-2-18(3-5-20)8-13-28-14-9-19(10-15-28)21-6-7-23(26)25-22(21)11-17-31-25/h6-7,11,17-20H,2-5,8-10,12-16H2,1H3,(H,27,29)/t18-,20- XTUBFYJCRZIUBT-KESTWPANSA-N 138463 US8877778, 67 D(2) dopamine receptor Homo sapiens 612.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385932 249815688 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272406 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(cc1)-n1cccn1 InChI=1S/C31H38N4O2/c36-31(25-7-11-27(12-8-25)35-18-2-17-32-35)33-26-9-5-23(6-10-26)13-19-34-20-14-24(15-21-34)28-3-1-4-30-29(28)16-22-37-30/h1-4,7-8,11-12,17-18,23-24,26H,5-6,9-10,13-16,19-22H2,(H,33,36)/t23-,26- JLRYOWKVNYLGFB-OJBMAJLDSA-N 138464 US8877778, 68 D(2) dopamine receptor Homo sapiens 1700 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385933 249815689 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272407 Cc1nc(no1)-c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C31H38N4O3/c1-21-32-30(34-38-21)24-7-9-25(10-8-24)31(36)33-26-11-5-22(6-12-26)13-17-35-18-14-23(15-19-35)27-3-2-4-29-28(27)16-20-37-29/h2-4,7-10,22-23,26H,5-6,11-20H2,1H3,(H,33,36)/t22-,26- NZPQNNBQTOVDCM-PGWJBFNOSA-N 138465 US8877778, 69 D(2) dopamine receptor Homo sapiens 3728 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385934 249815690 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272408 CS(=O)(=O)c1ccc(s1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H36N2O4S2/c1-35(31,32)26-10-9-25(34-26)27(30)28-21-7-5-19(6-8-21)11-15-29-16-12-20(13-17-29)22-3-2-4-24-23(22)14-18-33-24/h2-4,9-10,19-21H,5-8,11-18H2,1H3,(H,28,30)/t19-,21- RPZFDAKOXHZICV-XUTJKUGGSA-N 138466 US8877778, 70 D(2) dopamine receptor Homo sapiens 194.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385935 249815691 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272409 CC(C)(C)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C32H44N2O2/c1-32(2,3)26-11-9-25(10-12-26)31(35)33-27-13-7-23(8-14-27)15-19-34-20-16-24(17-21-34)28-5-4-6-30-29(28)18-22-36-30/h4-6,9-12,23-24,27H,7-8,13-22H2,1-3H3,(H,33,35)/t23-,27- DSJBBFGGCRIVIL-JIBACQESSA-N 138467 US8877778, 71 D(2) dopamine receptor Homo sapiens >10000000 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385936 249815692 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272410 CC(C)(O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H40N2O3/c1-26(2,30)18-25(29)27-21-8-6-19(7-9-21)10-14-28-15-11-20(12-16-28)22-4-3-5-24-23(22)13-17-31-24/h3-5,19-21,30H,6-18H2,1-2H3,(H,27,29)/t19-,21- XOOONTVCSUXSOA-XUTJKUGGSA-N 138468 US8877778, 72 D(2) dopamine receptor Homo sapiens 175.51 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386197 249815693 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272411 CCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C25H38N2O2/c1-2-4-25(28)26-21-9-7-19(8-10-21)11-15-27-16-12-20(13-17-27)22-5-3-6-24-23(22)14-18-29-24/h3,5-6,19-21H,2,4,7-18H2,1H3,(H,26,28)/t19-,21- SKIYXMOTQIREJJ-XUTJKUGGSA-N 138469 US8877778, 73 D(2) dopamine receptor Homo sapiens 196.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386198 249815694 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272412 FC(F)(F)CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C25H35F3N2O2/c26-25(27,28)13-8-24(31)29-20-6-4-18(5-7-20)9-14-30-15-10-19(11-16-30)21-2-1-3-23-22(21)12-17-32-23/h1-3,18-20H,4-17H2,(H,29,31)/t18-,20- FBSPYGXUZZFKDG-KESTWPANSA-N 138470 US8877778, 74 D(2) dopamine receptor Homo sapiens 253 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386199 249815695 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272413 CC(C)CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C27H42N2O2/c1-20(2)6-11-27(30)28-23-9-7-21(8-10-23)12-16-29-17-13-22(14-18-29)24-4-3-5-26-25(24)15-19-31-26/h3-5,20-23H,6-19H2,1-2H3,(H,28,30)/t21-,23- WLPHKXGJSXEPJH-AFARHQOCSA-N 138471 US8877778, 75 D(2) dopamine receptor Homo sapiens 1067.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386200 249815696 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272414 CCCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H40N2O2/c1-2-3-7-26(29)27-22-10-8-20(9-11-22)12-16-28-17-13-21(14-18-28)23-5-4-6-25-24(23)15-19-30-25/h4-6,20-22H,2-3,7-19H2,1H3,(H,27,29)/t20-,22- MKKJVJCUFYKFLO-AQYVVDRMSA-N 138472 US8877778, 76 D(2) dopamine receptor Homo sapiens 411 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386201 249815697 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272415 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(cc1)N1CCS(=O)(=O)CC1 InChI=1S/C32H43N3O4S/c36-32(26-6-10-28(11-7-26)35-19-22-40(37,38)23-20-35)33-27-8-4-24(5-9-27)12-16-34-17-13-25(14-18-34)29-2-1-3-31-30(29)15-21-39-31/h1-3,6-7,10-11,24-25,27H,4-5,8-9,12-23H2,(H,33,36)/t24-,27- GMWBGMFGQFHAIE-HNKWHGCMSA-N 138473 US8877778, 77 D(2) dopamine receptor Homo sapiens 329.1 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386202 249815698 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272416 O=C(NC1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc2ncccc2c1 InChI=1S/C31H37N3O2/c35-31(25-8-11-29-24(21-25)3-2-16-32-29)33-26-9-6-22(7-10-26)12-17-34-18-13-23(14-19-34)27-4-1-5-30-28(27)15-20-36-30/h1-5,8,11,16,21-23,26H,6-7,9-10,12-15,17-20H2,(H,33,35)/t22-,26? YWYZRJMGANXTJK-VYZLDGAWSA-N 138474 US8877778, 78 D(2) dopamine receptor Homo sapiens 3248 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386456 249815699 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272417 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc2OCOc2c1 InChI=1S/C29H36N2O4/c32-29(22-6-9-27-28(18-22)35-19-34-27)30-23-7-4-20(5-8-23)10-14-31-15-11-21(12-16-31)24-2-1-3-26-25(24)13-17-33-26/h1-3,6,9,18,20-21,23H,4-5,7-8,10-17,19H2,(H,30,32)/t20-,23- QYTGOVFVZCPBIO-JKIUYZKVSA-N 138475 US8877778, 79 D(2) dopamine receptor Homo sapiens 808.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386457 249815700 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272418 O=C(CC1COC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H38N2O3/c29-26(16-20-17-30-18-20)27-22-6-4-19(5-7-22)8-12-28-13-9-21(10-14-28)23-2-1-3-25-24(23)11-15-31-25/h1-3,19-22H,4-18H2,(H,27,29)/t19-,22- GJKGOLAEKKKXBM-XYWHTSSQSA-N 138476 US8877778, 80 D(2) dopamine receptor Homo sapiens 196.5 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386458 249815701 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272419 CC[C@@H](O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H40N2O3/c1-2-22(29)18-26(30)27-21-8-6-19(7-9-21)10-14-28-15-11-20(12-16-28)23-4-3-5-25-24(23)13-17-31-25/h3-5,19-22,29H,2,6-18H2,1H3,(H,27,30)/t19-,21-,22-/m1/s1 XJWLBKKTJHDHSX-CEMLEFRQSA-N 138477 US8877778, 81 D(2) dopamine receptor Homo sapiens 355.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138477&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386459 249815702 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272420 COC(CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)OC InChI=1S/C26H40N2O4/c1-30-26(31-2)18-25(29)27-21-8-6-19(7-9-21)10-14-28-15-11-20(12-16-28)22-4-3-5-24-23(22)13-17-32-24/h3-5,19-21,26H,6-18H2,1-2H3,(H,27,29)/t19-,21- RIVWPOSKFAXCII-XUTJKUGGSA-N 138478 US8877778, 82 D(2) dopamine receptor Homo sapiens 366.1 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138478&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386460 249815703 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272421 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C24H37N3O2/c1-26(2)24(28)25-20-8-6-18(7-9-20)10-14-27-15-11-19(12-16-27)21-4-3-5-23-22(21)13-17-29-23/h3-5,18-20H,6-17H2,1-2H3,(H,25,28)/t18-,20- LOMLSZYPQUWCNO-KESTWPANSA-N 138479 US8877778, 83 D(2) dopamine receptor Homo sapiens 69.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386461 249815704 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272422 CC(C)=CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H38N2O2/c1-19(2)18-26(29)27-22-8-6-20(7-9-22)10-14-28-15-11-21(12-16-28)23-4-3-5-25-24(23)13-17-30-25/h3-5,18,20-22H,6-17H2,1-2H3,(H,27,29)/t20-,22- SDWMTMWHNYEEAG-AQYVVDRMSA-N 138480 US8877778, 84 D(2) dopamine receptor Homo sapiens 73.9 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386714 249815705 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272423 C\C=C\CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C26H38N2O2/c1-2-3-7-26(29)27-22-10-8-20(9-11-22)12-16-28-17-13-21(14-18-28)23-5-4-6-25-24(23)15-19-30-25/h2-6,20-22H,7-19H2,1H3,(H,27,29)/b3-2+/t20-,22- WTRUJFPMRUJYBV-YONZVVFSSA-N 138481 US8877778, 85 D(2) dopamine receptor Homo sapiens 437.7 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138481&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386715 249815706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272424 CC#CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C25H34N2O2/c1-2-4-25(28)26-21-9-7-19(8-10-21)11-15-27-16-12-20(13-17-27)22-5-3-6-24-23(22)14-18-29-24/h3,5-6,19-21H,7-18H2,1H3,(H,26,28)/t19-,21- XBBWJMUBMHLUNQ-XUTJKUGGSA-N 138482 US8877778, 86 D(2) dopamine receptor Homo sapiens 118.4 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138482&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386716 249815707 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272425 O=CN[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C22H32N2O2/c25-16-23-19-6-4-17(5-7-19)8-12-24-13-9-18(10-14-24)20-2-1-3-22-21(20)11-15-26-22/h1-3,16-19H,4-15H2,(H,23,25)/t17-,19- GZNLRQUVYFCLCG-UAPYVXQJSA-N 138483 US8877778, 87 D(2) dopamine receptor Homo sapiens 167.2 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386717 249815708 C06049 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272426 CC(C)(C)Oc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C32H44N2O3/c1-32(2,3)37-27-13-9-25(10-14-27)31(35)33-26-11-7-23(8-12-26)15-19-34-20-16-24(17-21-34)28-5-4-6-30-29(28)18-22-36-30/h4-6,9-10,13-14,23-24,26H,7-8,11-12,15-22H2,1-3H3,(H,33,35)/t23-,26- XKUSJISCOLOOOS-OJBMAJLDSA-N 138484 US8877778, 88 D(2) dopamine receptor Homo sapiens >10000000 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386718 249815709 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272427 Clc1ccc(C(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3cccc4OCCc34)CC2)c(Cl)c1 InChI=1S/C28H34Cl2N2O2/c29-21-6-9-25(26(30)18-21)28(33)31-22-7-4-19(5-8-22)10-14-32-15-11-20(12-16-32)23-2-1-3-27-24(23)13-17-34-27/h1-3,6,9,18-20,22H,4-5,7-8,10-17H2,(H,31,33)/t19-,22- VZIIAQQJQFQYID-XYWHTSSQSA-N 138485 US8877778, 89 D(2) dopamine receptor Homo sapiens 233.5 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138485&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386719 249815710 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272428 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(cc1)-n1cccc1 InChI=1S/C32H39N3O2/c36-32(26-8-12-28(13-9-26)35-18-1-2-19-35)33-27-10-6-24(7-11-27)14-20-34-21-15-25(16-22-34)29-4-3-5-31-30(29)17-23-37-31/h1-5,8-9,12-13,18-19,24-25,27H,6-7,10-11,14-17,20-23H2,(H,33,36)/t24-,27- FMLDUWPAAHKNPY-HNKWHGCMSA-N 138486 US8877778, 90 D(2) dopamine receptor Homo sapiens 85.1 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386962 249815711 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272429 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(cc1)-c1ccccc1 InChI=1S/C34H40N2O2/c37-34(29-13-11-27(12-14-29)26-5-2-1-3-6-26)35-30-15-9-25(10-16-30)17-21-36-22-18-28(19-23-36)31-7-4-8-33-32(31)20-24-38-33/h1-8,11-14,25,28,30H,9-10,15-24H2,(H,35,37)/t25-,30- LYHUWMRZCXPRBP-BEESLVRJSA-N 138487 US8877778, 91 D(2) dopamine receptor Homo sapiens 501.4 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138487&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386963 249815712 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272430 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1)c1ccc(cc1)-c1cccnc1 InChI=1S/C33H39N3O2/c37-33(27-10-8-25(9-11-27)28-3-2-18-34-23-28)35-29-12-6-24(7-13-29)14-19-36-20-15-26(16-21-36)30-4-1-5-32-31(30)17-22-38-32/h1-5,8-11,18,23-24,26,29H,6-7,12-17,19-22H2,(H,35,37)/t24-,29- MOHZYINNROZMOQ-YLIUREIVSA-N 138488 US8877778, 92 D(2) dopamine receptor Homo sapiens 99.8 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386964 249815713 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272431 O=C(Cc1noc2ccccc12)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C30H37N3O3/c34-30(20-27-26-4-1-2-6-29(26)36-32-27)31-23-10-8-21(9-11-23)12-16-33-17-13-22(14-18-33)24-5-3-7-28-25(24)15-19-35-28/h1-7,21-23H,8-20H2,(H,31,34)/t21-,23- XOPMGCDIMXYMGV-AFARHQOCSA-N 138489 US8877778, 93 D(2) dopamine receptor Homo sapiens 243.6 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386965 249815714 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272432 O=C(Cc1ccc2OCOc2c1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C30H38N2O4/c33-30(19-22-6-9-28-29(18-22)36-20-35-28)31-24-7-4-21(5-8-24)10-14-32-15-11-23(12-16-32)25-2-1-3-27-26(25)13-17-34-27/h1-3,6,9,18,21,23-24H,4-5,7-8,10-17,19-20H2,(H,31,33)/t21-,24- ZTIHCPRBAJJIRW-SAIGFBBZSA-N 138490 US8877778, 94 D(2) dopamine receptor Homo sapiens 721.3 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138490&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57386966 249815715 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 272433 CS(=O)(=O)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2cccc3OCCc23)CC1 InChI=1S/C29H38N2O4S/c1-36(33,34)25-11-7-23(8-12-25)29(32)30-24-9-5-21(6-10-24)13-17-31-18-14-22(15-19-31)26-3-2-4-28-27(26)16-20-35-28/h2-4,7-8,11-12,21-22,24H,5-6,9-10,13-20H2,1H3,(H,30,32)/t21-,24- OVSOSNSBPWXIPD-SAIGFBBZSA-N 138491 US8877778, 95 D(2) dopamine receptor Homo sapiens 161.5 US Patent 10.7270/Q24J0CTP aid1800747 US8877778 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57387214 249815716 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 276571 Fc1ccc2Sc3ccccc3N=C(N3CCNCC3)c2c1 InChI=1S/C17H16FN3S/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2 CXKQSMUCGLKJEI-UHFFFAOYSA-N 141312 US8653257, 2-Fluoro-11-piperazin-1-yl-dibenzo[b,f][1,4]thiazepine D(2) dopamine receptor Homo sapiens 11 US Patent 10.7270/Q2DR2T69 aid1800807 US8653257 Brown, D; Damewood, JR; Edwards, P; Hulsizer, J; Muir, JC; Pierson, Jr., ME; Shenvi, AB; Wesolowski, S; Widzowski, D; Wood, M AstraZeneca AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44537860 251855593 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 276572 C1CN(CCN1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C17H17N3S/c1-3-7-15-13(5-1)17(20-11-9-18-10-12-20)19-14-6-2-4-8-16(14)21-15/h1-8,18H,9-12H2 JLOAJISUHPIQOX-UHFFFAOYSA-N 141313 US8653257, 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine D(2) dopamine receptor Homo sapiens 37 US Patent 10.7270/Q2DR2T69 aid1800807 US8653257 Brown, D; Damewood, JR; Edwards, P; Hulsizer, J; Muir, JC; Pierson, Jr., ME; Shenvi, AB; Wesolowski, S; Widzowski, D; Wood, M AstraZeneca AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141313&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11369918 251855594 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 276573 Clc1ccc2Sc3ccccc3N=C(N3CCNCC3)c2c1 InChI=1S/C17H16ClN3S/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2 NYXDYIWPZMXTPA-UHFFFAOYSA-N 141314 US8653257, 2-Chloro-11-piperazin-1-yl-dibenzo[b,f][1,4]thiazepine D(2) dopamine receptor Homo sapiens 0.7 US Patent 10.7270/Q2DR2T69 aid1800807 US8653257 Brown, D; Damewood, JR; Edwards, P; Hulsizer, J; Muir, JC; Pierson, Jr., ME; Shenvi, AB; Wesolowski, S; Widzowski, D; Wood, M AstraZeneca AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6453497 251855595 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 276574 CN1CCN(CC1)C1=Nc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClN3S/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 KAAZGXDPUNNEFN-UHFFFAOYSA-N 50040237 2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine D(2) dopamine receptor Homo sapiens 0.49 US Patent 10.7270/Q2DR2T69 aid1800807 US8653257 Brown, D; Damewood, JR; Edwards, P; Hulsizer, J; Muir, JC; Pierson, Jr., ME; Shenvi, AB; Wesolowski, S; Widzowski, D; Wood, M AstraZeneca AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16351 103972297 CHEMBL304902 ZINC26185346 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 276575 CN1CCN(CC1)C1=Nc2ccccc2Sc2ccc(F)cc12 InChI=1S/C18H18FN3S/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 GSYXWIMVZURMCS-UHFFFAOYSA-N 141315 US8653257, 2-Fluoro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine D(2) dopamine receptor Homo sapiens 1.1 US Patent 10.7270/Q2DR2T69 aid1800807 US8653257 Brown, D; Damewood, JR; Edwards, P; Hulsizer, J; Muir, JC; Pierson, Jr., ME; Shenvi, AB; Wesolowski, S; Widzowski, D; Wood, M AstraZeneca AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 58015268 251855596 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281253 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NCCC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144737 US8952128, 1 D(2) dopamine receptor Homo sapiens 10.8 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809272 252081014 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281254 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NCCCC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144738 US8952128, 2 D(2) dopamine receptor Homo sapiens 6.9 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809273 252081015 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281255 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NCCCCC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144739 US8952128, 3 D(2) dopamine receptor Homo sapiens 45.2 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809274 252081016 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281256 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144740 US8952128, 4 D(2) dopamine receptor Homo sapiens 182.5 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144740&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809275 252081017 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281257 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144741 US8952128, 5 D(2) dopamine receptor Homo sapiens 28.5 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144741&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809276 252081018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281258 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144742 US8952128, 6 D(2) dopamine receptor Homo sapiens 100.9 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809277 252081019 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281259 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)c(F)c2)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144743 US8952128, 6A D(2) dopamine receptor Homo sapiens 16.9 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144743&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809278 252081020 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281260 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2cc(F)cc(F)c2)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144744 US8952128, 6B D(2) dopamine receptor Homo sapiens 25.4 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144744&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809279 252081021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281261 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2cccc(F)c2)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144745 US8952128, 6C D(2) dopamine receptor Homo sapiens 30.3 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144745&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809280 252081022 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281262 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2F)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144746 US8952128, 6D D(2) dopamine receptor Homo sapiens 31.8 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144746&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809281 252081023 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281263 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2c(F)c(F)c(F)c(F)c2F)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144747 US8952128, 6E D(2) dopamine receptor Homo sapiens 40.4 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144747&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809282 252081024 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281264 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144748 US8952128, 7 D(2) dopamine receptor Homo sapiens 34.3 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144748&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809283 252081025 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281265 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NC[C@H](CCCCNC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144749 US8952128, 8 D(2) dopamine receptor Homo sapiens 112.8 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144749&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809284 252081026 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281266 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](CCCCNC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144750 US8952128, 9 D(2) dopamine receptor Homo sapiens 39.2 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144750&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809285 252081027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281267 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NCCS(=O)(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144751 US8952128, 10 D(2) dopamine receptor Homo sapiens 56.4 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144751&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809286 252081028 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281268 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NCC[S@](=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144752 US8952128, 11 D(2) dopamine receptor Homo sapiens 79.7 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144752&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809287 252081029 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281269 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NCC[S@@](=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144753 US8952128, 12::US8952128, 46 D(2) dopamine receptor Homo sapiens 255.1 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144753&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809288 252081030 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281270 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CS(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144755 US8952128, 13 D(2) dopamine receptor Homo sapiens 32.5 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809290 252081032 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281271 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NCCS(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144756 US8952128, 14 D(2) dopamine receptor Homo sapiens 76.5 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809291 252081033 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281272 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CS(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144757 US8952128, 15 D(2) dopamine receptor Homo sapiens 149.3 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144757&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809292 252081034 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281273 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NC[C@H](CCCCNC(=O)CS(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)NC(=O)CS(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144758 US8952128, 16 D(2) dopamine receptor Homo sapiens 22.5 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144758&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809293 252081035 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281274 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](CCCCNC(=O)CS(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)NC(=O)CS(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144759 US8952128, 17 D(2) dopamine receptor Homo sapiens 67.6 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809294 252081036 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281275 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CS(=O)(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144760 US8952128, 19 D(2) dopamine receptor Homo sapiens >1000 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809295 252081037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281276 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NCCS(=O)(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144761 US8952128, 20 D(2) dopamine receptor Homo sapiens 114.6 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809296 252081038 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277140 CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C23H32N2O2/c1-17(26)24-20-8-6-18(7-9-20)10-13-25-14-11-19(12-15-25)22-16-27-23-5-3-2-4-21(22)23/h2-5,16,18-20H,6-15H2,1H3,(H,24,26)/t18-,20- XJWCUVSKMVQPGX-KESTWPANSA-N 141759 US8921397, 1 D(2) dopamine receptor Homo sapiens 50.4 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674705 251911061 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277141 COCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C25H36N2O3/c1-29-17-13-25(28)26-21-8-6-19(7-9-21)10-14-27-15-11-20(12-16-27)23-18-30-24-5-3-2-4-22(23)24/h2-5,18-21H,6-17H2,1H3,(H,26,28)/t19-,21- NKQAJKSSUARMMF-XUTJKUGGSA-N 141760 US8921397, 2 D(2) dopamine receptor Homo sapiens 71.18 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674706 251911062 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277142 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C1CCOCC1 InChI=1S/C27H38N2O3/c30-27(22-12-17-31-18-13-22)28-23-7-5-20(6-8-23)9-14-29-15-10-21(11-16-29)25-19-32-26-4-2-1-3-24(25)26/h1-4,19-23H,5-18H2,(H,28,30)/t20-,23- AYSGDGVMVFJUQY-JKIUYZKVSA-N 141761 US8921397, 3 D(2) dopamine receptor Homo sapiens 37.32 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674707 251911063 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277143 O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C28H40N2O3/c31-28(19-22-12-17-32-18-13-22)29-24-7-5-21(6-8-24)9-14-30-15-10-23(11-16-30)26-20-33-27-4-2-1-3-25(26)27/h1-4,20-24H,5-19H2,(H,29,31)/t21-,24- HVMWQJLTYBIVCR-SAIGFBBZSA-N 141762 US8921397, 4 D(2) dopamine receptor Homo sapiens 77.56 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141762&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674822 251911064 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277144 CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C24H34N2O2/c1-2-24(27)25-20-9-7-18(8-10-20)11-14-26-15-12-19(13-16-26)22-17-28-23-6-4-3-5-21(22)23/h3-6,17-20H,2,7-16H2,1H3,(H,25,27)/t18-,20- MUNJPNWHOINDKG-KESTWPANSA-N 141763 US8921397, 5 D(2) dopamine receptor Homo sapiens 48.1 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141763&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674823 251911065 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277145 COCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C24H34N2O3/c1-28-17-24(27)25-20-8-6-18(7-9-20)10-13-26-14-11-19(12-15-26)22-16-29-23-5-3-2-4-21(22)23/h2-5,16,18-20H,6-15,17H2,1H3,(H,25,27)/t18-,20- RXMJGLCPVVEEJS-KESTWPANSA-N 141764 US8921397, 6 D(2) dopamine receptor Homo sapiens 80.1 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674824 251911066 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277146 CS(=O)(=O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C24H34N2O4S/c1-31(28,29)17-24(27)25-20-8-6-18(7-9-20)10-13-26-14-11-19(12-15-26)22-16-30-23-5-3-2-4-21(22)23/h2-5,16,18-20H,6-15,17H2,1H3,(H,25,27)/t18-,20- BYIJZPIPKRUSAC-KESTWPANSA-N 141765 US8921397, 7 D(2) dopamine receptor Homo sapiens 50.8 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674825 251911067 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277147 O=C(CC1COCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C27H38N2O4/c30-27(17-23-18-31-15-16-32-23)28-22-7-5-20(6-8-22)9-12-29-13-10-21(11-14-29)25-19-33-26-4-2-1-3-24(25)26/h1-4,19-23H,5-18H2,(H,28,30)/t20-,22-,23? CQUFCEROSHHDTD-YEMPIKNUSA-N 141766 US8921397, 8 D(2) dopamine receptor Homo sapiens 85.9 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674826 251911068 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277148 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccccc1 InChI=1S/C28H34N2O2/c31-28(23-6-2-1-3-7-23)29-24-12-10-21(11-13-24)14-17-30-18-15-22(16-19-30)26-20-32-27-9-5-4-8-25(26)27/h1-9,20-22,24H,10-19H2,(H,29,31)/t21-,24- PTNPPRPOWCBKGO-SAIGFBBZSA-N 141767 US8921397, 9 D(2) dopamine receptor Homo sapiens 32.32 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141767&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674827 251911069 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277149 Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3coc4ccccc34)CC2)on1 InChI=1S/C27H35N3O3/c1-19-16-23(33-29-19)17-27(31)28-22-8-6-20(7-9-22)10-13-30-14-11-21(12-15-30)25-18-32-26-5-3-2-4-24(25)26/h2-5,16,18,20-22H,6-15,17H2,1H3,(H,28,31)/t20-,22- LQSBOQJIPVGJNY-AQYVVDRMSA-N 141768 US8921397, 10 D(2) dopamine receptor Homo sapiens 83.59 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674940 251911070 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277150 OCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C23H32N2O3/c26-15-23(27)24-19-7-5-17(6-8-19)9-12-25-13-10-18(11-14-25)21-16-28-22-4-2-1-3-20(21)22/h1-4,16-19,26H,5-15H2,(H,24,27)/t17-,19- CSKYOEFARAEABU-UAPYVXQJSA-N 141769 US8921397, 11 D(2) dopamine receptor Homo sapiens 46.52 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141769&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674941 251911071 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281277 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CS(=O)(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144762 US8952128, 21 D(2) dopamine receptor Homo sapiens >1000 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144762&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809297 252081039 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281278 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)N(CCCNC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)C(C)=O 144763 US8952128, 22 D(2) dopamine receptor Homo sapiens 199.5 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144763&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809298 252081040 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281279 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144764 US8952128, 23 D(2) dopamine receptor Homo sapiens 328.3 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809299 252081041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281280 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144765 US8952128, 24 D(2) dopamine receptor Homo sapiens 175.3 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809300 252081042 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281281 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144766 US8952128, 25 D(2) dopamine receptor Homo sapiens 272.4 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809301 252081043 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281282 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NCCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144767 US8952128, 26 D(2) dopamine receptor Homo sapiens 309 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144767&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809302 252081044 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281283 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC[C@@H](Cc1ccc(O)cc1)NC(=O)CCN(C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)C(C)=O 144768 US8952128, 27 D(2) dopamine receptor Homo sapiens 276.8 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809303 252081045 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281284 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)N(CCCN(C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)C(C)=O)C(C)=O 144769 US8952128, 28 D(2) dopamine receptor Homo sapiens 39.9 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144769&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809304 252081046 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281285 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC[C@@H](Cc1ccc(O)cc1)NCCCN(C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)C(C)=O 144770 US8952128, 28A D(2) dopamine receptor Homo sapiens 14 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809305 252081047 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281286 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)N(CCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)CCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144771 US8952128, 29 D(2) dopamine receptor Homo sapiens 135.2 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809306 252081048 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281287 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NCCCN(C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)C(C)=O 144772 US8952128, 29A D(2) dopamine receptor Homo sapiens 46.8 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809307 252081049 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281288 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144773 US8952128, 30::US8952128, 32 D(2) dopamine receptor Homo sapiens 24.2 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809308 252081050 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281289 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144774 US8952128, 31::US8952128, 43 D(2) dopamine receptor Homo sapiens 38.6 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809309 252081051 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281290 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144773 US8952128, 30::US8952128, 32 D(2) dopamine receptor Homo sapiens 44 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809308 252081050 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281291 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144776 US8952128, 33 D(2) dopamine receptor Homo sapiens 15 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144776&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809310 252081052 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281292 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144777 US8952128, 34 D(2) dopamine receptor Homo sapiens 298.9 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809311 252081053 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281293 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)N(CCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)CCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144778 US8952128, 35 D(2) dopamine receptor Homo sapiens 345.2 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809312 252081054 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281294 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144779 US8952128, 37 D(2) dopamine receptor Homo sapiens 25.3 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144779&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809313 252081055 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281295 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144780 US8952128, 38 D(2) dopamine receptor Homo sapiens 179.4 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809314 252081056 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281296 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)N(CCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)CCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144781 US8952128, 39 D(2) dopamine receptor Homo sapiens 329.7 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144781&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809315 252081057 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281297 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)N(CCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)CCSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144782 US8952128, 40 D(2) dopamine receptor Homo sapiens 444.9 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809316 252081058 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281298 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC[C@@H](Cc1ccc(O)cc1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144783 US8952128, 41 D(2) dopamine receptor Homo sapiens 8.5 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144783&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809317 252081059 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281299 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC[C@H](Cc1ccc(O)cc1)NC(=O)CCN(C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)S(C)(=O)=O 144784 US8952128, 42 D(2) dopamine receptor Homo sapiens 285.3 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809318 252081060 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281300 C[C@@H](O)C1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144786 US8952128, 44 D(2) dopamine receptor Homo sapiens 199.6 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809319 252081061 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281301 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)NCC[S@@](=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144753 US8952128, 12::US8952128, 46 D(2) dopamine receptor Homo sapiens 31.6 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144753&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809288 252081030 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281302 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NC[C@H](CCCCNC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1)NC(=O)CSC[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144788 US8952128, 47 D(2) dopamine receptor Homo sapiens 84.2 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809320 252081062 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 281303 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O)NCCCS(=O)(=O)C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 144789 US8952128, 48 D(2) dopamine receptor Homo sapiens 19.4 7.6 US Patent 10.7270/Q2057DNG aid1800909 US8952128 Dong, ZX; Shen, Y; Kim, SH Ipsen Pharma S.A.S. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91809321 252081063 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277152 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)N1CCOCC1 InChI=1S/C32H41N3O3/c36-32(26-7-11-28(12-8-26)35-19-21-37-22-20-35)33-27-9-5-24(6-10-27)13-16-34-17-14-25(15-18-34)30-23-38-31-4-2-1-3-29(30)31/h1-4,7-8,11-12,23-25,27H,5-6,9-10,13-22H2,(H,33,36)/t24-,27- CWGVPEOXWFRWOV-HNKWHGCMSA-N 141771 US8921397, 13 D(2) dopamine receptor Homo sapiens 406.32 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674943 251911073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277153 CC(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C25H36N2O2/c1-18(2)25(28)26-21-9-7-19(8-10-21)11-14-27-15-12-20(13-16-27)23-17-29-24-6-4-3-5-22(23)24/h3-6,17-21H,7-16H2,1-2H3,(H,26,28)/t19-,21- YCVCSJNOURLGPF-XUTJKUGGSA-N 141772 US8921397, 14 D(2) dopamine receptor Homo sapiens 39.54 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674944 251911074 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277154 CC(C)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H38N2O2/c1-19(2)17-26(29)27-22-9-7-20(8-10-22)11-14-28-15-12-21(13-16-28)24-18-30-25-6-4-3-5-23(24)25/h3-6,18-22H,7-17H2,1-2H3,(H,27,29)/t20-,22- OXYSILQZQLVAHW-AQYVVDRMSA-N 141773 US8921397, 15 D(2) dopamine receptor Homo sapiens 43.49 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674945 251911075 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277155 CC(C)(O)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C25H36N2O3/c1-25(2,29)24(28)26-20-9-7-18(8-10-20)11-14-27-15-12-19(13-16-27)22-17-30-23-6-4-3-5-21(22)23/h3-6,17-20,29H,7-16H2,1-2H3,(H,26,28)/t18-,20- VFSAAGKCBXDENJ-KESTWPANSA-N 141774 US8921397, 16 D(2) dopamine receptor Homo sapiens 53.71 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675059 251911076 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277156 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C1CCOC1 InChI=1S/C26H36N2O3/c29-26(21-12-16-30-17-21)27-22-7-5-19(6-8-22)9-13-28-14-10-20(11-15-28)24-18-31-25-4-2-1-3-23(24)25/h1-4,18-22H,5-17H2,(H,27,29)/t19-,21?,22- NLDGWRVWWZGYFC-CTTUZFCVSA-N 141775 US8921397, 17 D(2) dopamine receptor Homo sapiens 52.97 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675060 251911077 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277157 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C1CCCO1 InChI=1S/C26H36N2O3/c29-26(25-6-3-17-30-25)27-21-9-7-19(8-10-21)11-14-28-15-12-20(13-16-28)23-18-31-24-5-2-1-4-22(23)24/h1-2,4-5,18-21,25H,3,6-17H2,(H,27,29)/t19-,21-,25? IDWFBPRPZDTKJU-RKTRBERCSA-N 141776 US8921397, 18 D(2) dopamine receptor Homo sapiens 81.48 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141776&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675061 251911078 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277158 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccnc2ccccc12 InChI=1S/C31H35N3O2/c35-31(27-13-17-32-29-7-3-1-5-25(27)29)33-24-11-9-22(10-12-24)14-18-34-19-15-23(16-20-34)28-21-36-30-8-4-2-6-26(28)30/h1-8,13,17,21-24H,9-12,14-16,18-20H2,(H,33,35)/t22-,24- GAXMVVSYOXLLNF-HCGLCNNCSA-N 141777 US8921397, 19 D(2) dopamine receptor Homo sapiens 96.68 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675062 251911079 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277159 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C1CCC1 InChI=1S/C26H36N2O2/c29-26(21-4-3-5-21)27-22-10-8-19(9-11-22)12-15-28-16-13-20(14-17-28)24-18-30-25-7-2-1-6-23(24)25/h1-2,6-7,18-22H,3-5,8-17H2,(H,27,29)/t19-,22- XXUXRIDSKSDOGY-XYWHTSSQSA-N 141778 US8921397, 20 D(2) dopamine receptor Homo sapiens 38.05 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675063 251911080 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277160 OCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C24H34N2O3/c27-16-12-24(28)25-20-7-5-18(6-8-20)9-13-26-14-10-19(11-15-26)22-17-29-23-4-2-1-3-21(22)23/h1-4,17-20,27H,5-16H2,(H,25,28)/t18-,20- QTXHMWUMSJMZON-KESTWPANSA-N 141779 US8921397, 21 D(2) dopamine receptor Homo sapiens 62.94 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141779&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675064 251911081 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277161 OC1(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C25H34N2O3/c28-24(25(29)12-13-25)26-20-7-5-18(6-8-20)9-14-27-15-10-19(11-16-27)22-17-30-23-4-2-1-3-21(22)23/h1-4,17-20,29H,5-16H2,(H,26,28)/t18-,20- HUVWCUMZGKOSQX-KESTWPANSA-N 141780 US8921397, 22 D(2) dopamine receptor Homo sapiens 47.49 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675173 251911082 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277162 O=C(CC#N)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C24H31N3O2/c25-13-9-24(28)26-20-7-5-18(6-8-20)10-14-27-15-11-19(12-16-27)22-17-29-23-4-2-1-3-21(22)23/h1-4,17-20H,5-12,14-16H2,(H,26,28)/t18-,20- BKYLOINGTUMEIT-KESTWPANSA-N 141781 US8921397, 23 D(2) dopamine receptor Homo sapiens 41.51 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141781&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675174 251911083 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277163 Fc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C28H33FN2O2/c29-23-9-7-22(8-10-23)28(32)30-24-11-5-20(6-12-24)13-16-31-17-14-21(15-18-31)26-19-33-27-4-2-1-3-25(26)27/h1-4,7-10,19-21,24H,5-6,11-18H2,(H,30,32)/t20-,24- IPANXDCFQPUSKK-LSNLESRRSA-N 141782 US8921397, 24 D(2) dopamine receptor Homo sapiens 68.89 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675175 251911084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277164 O=C(CC1CC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H36N2O2/c29-26(17-20-5-6-20)27-22-9-7-19(8-10-22)11-14-28-15-12-21(13-16-28)24-18-30-25-4-2-1-3-23(24)25/h1-4,18-22H,5-17H2,(H,27,29)/t19-,22- WOCTZIGUHYMWQK-XYWHTSSQSA-N 141783 US8921397, 25 D(2) dopamine receptor Homo sapiens 33.71 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141783&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675176 251911085 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277165 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C1CCCOC1 InChI=1S/C27H38N2O3/c30-27(22-4-3-17-31-18-22)28-23-9-7-20(8-10-23)11-14-29-15-12-21(13-16-29)25-19-32-26-6-2-1-5-24(25)26/h1-2,5-6,19-23H,3-4,7-18H2,(H,28,30)/t20-,22?,23- YXORYFHPDVVIAR-FXCIWXGGSA-N 141784 US8921397, 26 D(2) dopamine receptor Homo sapiens 37.09 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675177 251911086 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277166 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C1CC1 InChI=1S/C25H34N2O2/c28-25(20-7-8-20)26-21-9-5-18(6-10-21)11-14-27-15-12-19(13-16-27)23-17-29-24-4-2-1-3-22(23)24/h1-4,17-21H,5-16H2,(H,26,28)/t18-,21- DXBDRGKOIPOWRV-XGAFWQRZSA-N 141785 US8921397, 27 D(2) dopamine receptor Homo sapiens 22.68 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675178 251911087 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277167 CC(C)(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H38N2O2/c1-26(2,3)25(29)27-21-10-8-19(9-11-21)12-15-28-16-13-20(14-17-28)23-18-30-24-7-5-4-6-22(23)24/h4-7,18-21H,8-17H2,1-3H3,(H,27,29)/t19-,21- IKAPCPDHWACXJE-XUTJKUGGSA-N 141786 US8921397, 28 D(2) dopamine receptor Homo sapiens 37.96 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675298 251911088 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277168 O=C(CC1CCCO1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C27H38N2O3/c30-27(18-23-4-3-17-31-23)28-22-9-7-20(8-10-22)11-14-29-15-12-21(13-16-29)25-19-32-26-6-2-1-5-24(25)26/h1-2,5-6,19-23H,3-4,7-18H2,(H,28,30)/t20-,22-,23? AMCLEKXUPLBXGM-YEMPIKNUSA-N 141787 US8921397, 29 D(2) dopamine receptor Homo sapiens 52.86 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141787&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675299 251911089 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277169 FC1(F)CC1C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C25H32F2N2O2/c26-25(27)15-22(25)24(30)28-19-7-5-17(6-8-19)9-12-29-13-10-18(11-14-29)21-16-31-23-4-2-1-3-20(21)23/h1-4,16-19,22H,5-15H2,(H,28,30)/t17-,19-,22? LJWIFZKAUORKLB-NRCGHCQOSA-N 141788 US8921397, 30 D(2) dopamine receptor Homo sapiens 28.11 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675300 251911090 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277170 CCC(C)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H38N2O2/c1-3-19(2)26(29)27-22-10-8-20(9-11-22)12-15-28-16-13-21(14-17-28)24-18-30-25-7-5-4-6-23(24)25/h4-7,18-22H,3,8-17H2,1-2H3,(H,27,29)/t19?,20-,22- UGPMJKXBWQUZNC-RVZUZXSLSA-N 141789 US8921397, 31 D(2) dopamine receptor Homo sapiens 46.02 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675301 251911091 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277171 OC(C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C(F)(F)F InChI=1S/C24H31F3N2O3/c25-24(26,27)22(30)23(31)28-18-7-5-16(6-8-18)9-12-29-13-10-17(11-14-29)20-15-32-21-4-2-1-3-19(20)21/h1-4,15-18,22,30H,5-14H2,(H,28,31)/t16-,18-,22? NHQVWADCZMCLLL-MYKGNVCDSA-N 141790 US8921397, 32 D(2) dopamine receptor Homo sapiens 46.39 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675302 251911092 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277172 CCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C25H36N2O2/c1-2-5-25(28)26-21-10-8-19(9-11-21)12-15-27-16-13-20(14-17-27)23-18-29-24-7-4-3-6-22(23)24/h3-4,6-7,18-21H,2,5,8-17H2,1H3,(H,26,28)/t19-,21- PHVNNOMMTJPRIX-XUTJKUGGSA-N 141791 US8921397, 33 D(2) dopamine receptor Homo sapiens 45.27 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675303 251911093 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277173 CC(C)(O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H38N2O3/c1-26(2,30)17-25(29)27-21-9-7-19(8-10-21)11-14-28-15-12-20(13-16-28)23-18-31-24-6-4-3-5-22(23)24/h3-6,18-21,30H,7-17H2,1-2H3,(H,27,29)/t19-,21- IPXYCJHALCJMEQ-XUTJKUGGSA-N 141792 US8921397, 34 D(2) dopamine receptor Homo sapiens 41.33 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675430 251911094 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277174 O[C@H](CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C(F)(F)F InChI=1S/C25H33F3N2O3/c26-25(27,28)23(31)15-24(32)29-19-7-5-17(6-8-19)9-12-30-13-10-18(11-14-30)21-16-33-22-4-2-1-3-20(21)22/h1-4,16-19,23,31H,5-15H2,(H,29,32)/t17-,19-,23-/m1/s1 QTEIKHHDCPQIMO-LYHRCORUSA-N 141793 US8921397, 35 D(2) dopamine receptor Homo sapiens 50.42 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675431 251911095 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277175 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C22H32N2O3S/c1-28(25,26)23-19-8-6-17(7-9-19)10-13-24-14-11-18(12-15-24)21-16-27-22-5-3-2-4-20(21)22/h2-5,16-19,23H,6-15H2,1H3/t17-,19- QAAOBQZCHWUKTE-UAPYVXQJSA-N 141794 US8921397, 36 D(2) dopamine receptor Homo sapiens 47.35 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141794&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675432 251911096 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277176 CCS(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C23H34N2O3S/c1-2-29(26,27)24-20-9-7-18(8-10-20)11-14-25-15-12-19(13-16-25)22-17-28-23-6-4-3-5-21(22)23/h3-6,17-20,24H,2,7-16H2,1H3/t18-,20- SIJIBHRUTSSJLY-KESTWPANSA-N 141795 US8921397, 37 D(2) dopamine receptor Homo sapiens 47.99 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141795&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675433 251911097 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277177 Cc1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C28H36N2O3S/c1-21-6-12-25(13-7-21)34(31,32)29-24-10-8-22(9-11-24)14-17-30-18-15-23(16-19-30)27-20-33-28-5-3-2-4-26(27)28/h2-7,12-13,20,22-24,29H,8-11,14-19H2,1H3/t22-,24- FEXBUZQQTXAUHH-HCGLCNNCSA-N 141796 US8921397, 38 D(2) dopamine receptor Homo sapiens 58.62 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675434 251911098 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277178 FC(F)(F)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C23H29F3N2O2/c24-23(25,26)22(29)27-18-7-5-16(6-8-18)9-12-28-13-10-17(11-14-28)20-15-30-21-4-2-1-3-19(20)21/h1-4,15-18H,5-14H2,(H,27,29)/t16-,18- MOINQXFCUHCNNN-SAABIXHNSA-N 141797 US8921397, 39 D(2) dopamine receptor Homo sapiens 37.47 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675435 251911099 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277179 CC(C)(C)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C27H40N2O2/c1-27(2,3)18-26(30)28-22-10-8-20(9-11-22)12-15-29-16-13-21(14-17-29)24-19-31-25-7-5-4-6-23(24)25/h4-7,19-22H,8-18H2,1-3H3,(H,28,30)/t20-,22- ISELLYVTONRQOI-AQYVVDRMSA-N 141798 US8921397, 40 D(2) dopamine receptor Homo sapiens 53.03 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673787 251911100 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277180 Cc1cc(on1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H33N3O3/c1-18-16-25(32-28-18)26(30)27-21-8-6-19(7-9-21)10-13-29-14-11-20(12-15-29)23-17-31-24-5-3-2-4-22(23)24/h2-5,16-17,19-21H,6-15H2,1H3,(H,27,30)/t19-,21- QKNMUTJKRIBDKW-XUTJKUGGSA-N 141799 US8921397, 41 D(2) dopamine receptor Homo sapiens 36.41 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673788 251911101 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277181 CN(C)C(=O)CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C27H39N3O3/c1-29(2)27(32)12-11-26(31)28-22-9-7-20(8-10-22)13-16-30-17-14-21(15-18-30)24-19-33-25-6-4-3-5-23(24)25/h3-6,19-22H,7-18H2,1-2H3,(H,28,31)/t20-,22- PLAPJTQAKKRSBQ-AQYVVDRMSA-N 141800 US8921397, 42 D(2) dopamine receptor Homo sapiens 92.3 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673789 251911102 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277182 CN(C)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C23H35N3O3S/c1-25(2)30(27,28)24-20-9-7-18(8-10-20)11-14-26-15-12-19(13-16-26)22-17-29-23-6-4-3-5-21(22)23/h3-6,17-20,24H,7-16H2,1-2H3/t18-,20- ZPVXYYUZSYUVBO-KESTWPANSA-N 141801 US8921397, 43 D(2) dopamine receptor Homo sapiens 47.02 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673790 251911103 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277183 FC(F)(F)CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C25H33F3N2O2/c26-25(27,28)13-9-24(31)29-20-7-5-18(6-8-20)10-14-30-15-11-19(12-16-30)22-17-32-23-4-2-1-3-21(22)23/h1-4,17-20H,5-16H2,(H,29,31)/t18-,20- UPYKABFZBCHNJS-KESTWPANSA-N 141802 US8921397, 44 D(2) dopamine receptor Homo sapiens 61.16 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673791 251911104 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277184 CC(C)CCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C27H40N2O2/c1-20(2)7-12-27(30)28-23-10-8-21(9-11-23)13-16-29-17-14-22(15-18-29)25-19-31-26-6-4-3-5-24(25)26/h3-6,19-23H,7-18H2,1-2H3,(H,28,30)/t21-,23- DBHSOMRLOFZXDC-AFARHQOCSA-N 141803 US8921397, 45 D(2) dopamine receptor Homo sapiens 65.98 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673916 251911105 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277185 CC[C@@H](O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H38N2O3/c1-2-22(29)17-26(30)27-21-9-7-19(8-10-21)11-14-28-15-12-20(13-16-28)24-18-31-25-6-4-3-5-23(24)25/h3-6,18-22,29H,2,7-17H2,1H3,(H,27,30)/t19-,21-,22-/m1/s1 LKMYYERAFNDIAS-CEMLEFRQSA-N 141804 US8921397, 46 D(2) dopamine receptor Homo sapiens 55.43 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674141 251911106 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277186 CC[C@H](O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H38N2O3/c1-2-22(29)17-26(30)27-21-9-7-19(8-10-21)11-14-28-15-12-20(13-16-28)24-18-31-25-6-4-3-5-23(24)25/h3-6,18-22,29H,2,7-17H2,1H3,(H,27,30)/t19-,21-,22-/m0/s1 LKMYYERAFNDIAS-BVSLBCMMSA-N 141805 US8921397, 47 D(2) dopamine receptor Homo sapiens 33.75 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674142 251911107 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277187 O=C(CC1CCC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C27H38N2O2/c30-27(18-21-4-3-5-21)28-23-10-8-20(9-11-23)12-15-29-16-13-22(14-17-29)25-19-31-26-7-2-1-6-24(25)26/h1-2,6-7,19-23H,3-5,8-18H2,(H,28,30)/t20-,23- YBUAHTMMKRAXBO-JKIUYZKVSA-N 141806 US8921397, 48 D(2) dopamine receptor Homo sapiens 58.22 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674143 251911108 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277188 Clc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C28H33ClN2O2/c29-23-9-7-22(8-10-23)28(32)30-24-11-5-20(6-12-24)13-16-31-17-14-21(15-18-31)26-19-33-27-4-2-1-3-25(26)27/h1-4,7-10,19-21,24H,5-6,11-18H2,(H,30,32)/t20-,24- RYGODERPXMWCPP-LSNLESRRSA-N 141807 US8921397, 49 D(2) dopamine receptor Homo sapiens 25.8 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674144 251911109 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277189 FC(F)(F)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C29H33F3N2O2/c30-29(31,32)23-9-7-22(8-10-23)28(35)33-24-11-5-20(6-12-24)13-16-34-17-14-21(15-18-34)26-19-36-27-4-2-1-3-25(26)27/h1-4,7-10,19-21,24H,5-6,11-18H2,(H,33,35)/t20-,24- LVXRWLDIURXUJE-LSNLESRRSA-N 141808 US8921397, 50 D(2) dopamine receptor Homo sapiens 151.81 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674145 251911110 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277190 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)N1CCCCC1 InChI=1S/C33H43N3O2/c37-33(27-10-14-29(15-11-27)36-19-4-1-5-20-36)34-28-12-8-25(9-13-28)16-21-35-22-17-26(18-23-35)31-24-38-32-7-3-2-6-30(31)32/h2-3,6-7,10-11,14-15,24-26,28H,1,4-5,8-9,12-13,16-23H2,(H,34,37)/t25-,28- AYAGATABYZSYEZ-FCMXBYMOSA-N 141809 US8921397, 51 D(2) dopamine receptor Homo sapiens 345.18 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673917 251911111 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277191 COC(CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)OC InChI=1S/C26H38N2O4/c1-30-26(31-2)17-25(29)27-21-9-7-19(8-10-21)11-14-28-15-12-20(13-16-28)23-18-32-24-6-4-3-5-22(23)24/h3-6,18-21,26H,7-17H2,1-2H3,(H,27,29)/t19-,21- MGRVYPIMNDNBRD-XUTJKUGGSA-N 141810 US8921397, 52 D(2) dopamine receptor Homo sapiens 48.85 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 89123978 251911112 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277192 CC(C)=CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H36N2O2/c1-19(2)17-26(29)27-22-9-7-20(8-10-22)11-14-28-15-12-21(13-16-28)24-18-30-25-6-4-3-5-23(24)25/h3-6,17-18,20-22H,7-16H2,1-2H3,(H,27,29)/t20-,22- AYQGEWALVNGKIC-AQYVVDRMSA-N 141811 US8921397, 53 D(2) dopamine receptor Homo sapiens 18.01 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673919 251911113 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277193 C\C=C\CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H36N2O2/c1-2-3-8-26(29)27-22-11-9-20(10-12-22)13-16-28-17-14-21(15-18-28)24-19-30-25-7-5-4-6-23(24)25/h2-7,19-22H,8-18H2,1H3,(H,27,29)/b3-2+/t20-,22- NGHDXYJXIZZENU-YONZVVFSSA-N 141812 US8921397, 54 D(2) dopamine receptor Homo sapiens 57.95 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673920 251911114 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277194 CC#CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C25H32N2O2/c1-2-5-25(28)26-21-10-8-19(9-11-21)12-15-27-16-13-20(14-17-27)23-18-29-24-7-4-3-6-22(23)24/h3-4,6-7,18-21H,8-17H2,1H3,(H,26,28)/t19-,21- YCFPUDBYSCLGNZ-XUTJKUGGSA-N 141813 US8921397, 55 D(2) dopamine receptor Homo sapiens 25.62 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673921 251911115 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277195 O=CN[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C22H30N2O2/c25-16-23-19-7-5-17(6-8-19)9-12-24-13-10-18(11-14-24)21-15-26-22-4-2-1-3-20(21)22/h1-4,15-19H,5-14H2,(H,23,25)/t17-,19- SIWFRLSPUANOPO-UAPYVXQJSA-N 141814 US8921397, 56 D(2) dopamine receptor Homo sapiens 38.76 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674024 251911116 C06049 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277196 CCCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H38N2O2/c1-2-3-8-26(29)27-22-11-9-20(10-12-22)13-16-28-17-14-21(15-18-28)24-19-30-25-7-5-4-6-23(24)25/h4-7,19-22H,2-3,8-18H2,1H3,(H,27,29)/t20-,22- PMXOLMUJYKILQT-AQYVVDRMSA-N 141815 US8921397, 57 D(2) dopamine receptor Homo sapiens 65.71 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674025 251911117 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277197 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc2OCOc2c1 InChI=1S/C29H34N2O4/c32-29(22-7-10-27-28(17-22)35-19-34-27)30-23-8-5-20(6-9-23)11-14-31-15-12-21(13-16-31)25-18-33-26-4-2-1-3-24(25)26/h1-4,7,10,17-18,20-21,23H,5-6,8-9,11-16,19H2,(H,30,32)/t20-,23- MASFGJOTAOERQU-JKIUYZKVSA-N 141816 US8921397, 58 D(2) dopamine receptor Homo sapiens 28.63 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674026 251911118 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277198 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)-n1cccn1 InChI=1S/C31H36N4O2/c36-31(25-8-12-27(13-9-25)35-18-3-17-32-35)33-26-10-6-23(7-11-26)14-19-34-20-15-24(16-21-34)29-22-37-30-5-2-1-4-28(29)30/h1-5,8-9,12-13,17-18,22-24,26H,6-7,10-11,14-16,19-21H2,(H,33,36)/t23-,26- ONXKQTHNJXTCGP-OJBMAJLDSA-N 141817 US8921397, 59 D(2) dopamine receptor Homo sapiens 46.9 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674027 251911119 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277199 CC(C)(C)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C32H42N2O2/c1-32(2,3)26-12-10-25(11-13-26)31(35)33-27-14-8-23(9-15-27)16-19-34-20-17-24(18-21-34)29-22-36-30-7-5-4-6-28(29)30/h4-7,10-13,22-24,27H,8-9,14-21H2,1-3H3,(H,33,35)/t23-,27- AGZZUNBFSOFXTB-JIBACQESSA-N 141818 US8921397, 60 D(2) dopamine receptor Homo sapiens 1111.22 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674028 251911120 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277200 Cc1nc(no1)-c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C31H36N4O3/c1-21-32-30(34-38-21)24-8-10-25(11-9-24)31(36)33-26-12-6-22(7-13-26)14-17-35-18-15-23(16-19-35)28-20-37-29-5-3-2-4-27(28)29/h2-5,8-11,20,22-23,26H,6-7,12-19H2,1H3,(H,33,36)/t22-,26- WVGMMWFIRBRTKW-PGWJBFNOSA-N 141819 US8921397, 61 D(2) dopamine receptor Homo sapiens 226.91 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675484 251911121 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277201 CN1CCN(CC1)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C33H44N4O2/c1-35-20-22-37(23-21-35)29-12-8-27(9-13-29)33(38)34-28-10-6-25(7-11-28)14-17-36-18-15-26(16-19-36)31-24-39-32-5-3-2-4-30(31)32/h2-5,8-9,12-13,24-26,28H,6-7,10-11,14-23H2,1H3,(H,34,38)/t25-,28- FWRKTWHTQZRAPD-FCMXBYMOSA-N 141820 US8921397, 62 D(2) dopamine receptor Homo sapiens 50.09 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141820&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675485 251911122 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277202 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)-c1ccccc1 InChI=1S/C34H38N2O2/c37-34(29-14-12-27(13-15-29)26-6-2-1-3-7-26)35-30-16-10-25(11-17-30)18-21-36-22-19-28(20-23-36)32-24-38-33-9-5-4-8-31(32)33/h1-9,12-15,24-25,28,30H,10-11,16-23H2,(H,35,37)/t25-,30- XCWPAVYMGKFSJB-BEESLVRJSA-N 141821 US8921397, 63 D(2) dopamine receptor Homo sapiens 22.11 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141821&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675486 251911123 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277203 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)-c1cccnc1 InChI=1S/C33H37N3O2/c37-33(27-11-9-25(10-12-27)28-4-3-18-34-22-28)35-29-13-7-24(8-14-29)15-19-36-20-16-26(17-21-36)31-23-38-32-6-2-1-5-30(31)32/h1-6,9-12,18,22-24,26,29H,7-8,13-17,19-21H2,(H,35,37)/t24-,29- UAVOWOKUOJZVHZ-YLIUREIVSA-N 141822 US8921397, 64 D(2) dopamine receptor Homo sapiens 16.72 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675487 251911124 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277204 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(nc1)N1CCOCC1 InChI=1S/C31H40N4O3/c36-31(25-7-10-30(32-21-25)35-17-19-37-20-18-35)33-26-8-5-23(6-9-26)11-14-34-15-12-24(13-16-34)28-22-38-29-4-2-1-3-27(28)29/h1-4,7,10,21-24,26H,5-6,8-9,11-20H2,(H,33,36)/t23-,26- IMAGMLAZQQRSFA-OJBMAJLDSA-N 141823 US8921397, 65 D(2) dopamine receptor Homo sapiens 51.8 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675488 251911125 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277205 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)N1CCS(=O)(=O)CC1 InChI=1S/C32H41N3O4S/c36-32(26-7-11-28(12-8-26)35-19-21-40(37,38)22-20-35)33-27-9-5-24(6-10-27)13-16-34-17-14-25(15-18-34)30-23-39-31-4-2-1-3-29(30)31/h1-4,7-8,11-12,23-25,27H,5-6,9-10,13-22H2,(H,33,36)/t24-,27- NWFVAWLUQHQVSN-HNKWHGCMSA-N 141824 US8921397, 66 D(2) dopamine receptor Homo sapiens 19.22 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141824&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675528 251911126 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277206 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1cnc(cn1)N1CCOCC1 InChI=1S/C30H39N5O3/c36-30(27-19-32-29(20-31-27)35-15-17-37-18-16-35)33-24-7-5-22(6-8-24)9-12-34-13-10-23(11-14-34)26-21-38-28-4-2-1-3-25(26)28/h1-4,19-24H,5-18H2,(H,33,36)/t22-,24- FEYWSFCMYGDDGW-HCGLCNNCSA-N 141825 US8921397, 67 D(2) dopamine receptor Homo sapiens 105.59 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141825&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675509 251911127 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277207 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)-n1cccc1 InChI=1S/C32H37N3O2/c36-32(26-9-13-28(14-10-26)35-18-3-4-19-35)33-27-11-7-24(8-12-27)15-20-34-21-16-25(17-22-34)30-23-37-31-6-2-1-5-29(30)31/h1-6,9-10,13-14,18-19,23-25,27H,7-8,11-12,15-17,20-22H2,(H,33,36)/t24-,27- TUHWCWZHGQPAEF-HNKWHGCMSA-N 141826 US8921397, 68 D(2) dopamine receptor Homo sapiens 34.26 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675510 251911128 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277208 Cc1ccc(cn1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C28H35N3O2/c1-20-6-9-23(18-29-20)28(32)30-24-10-7-21(8-11-24)12-15-31-16-13-22(14-17-31)26-19-33-27-5-3-2-4-25(26)27/h2-6,9,18-19,21-22,24H,7-8,10-17H2,1H3,(H,30,32)/t21-,24- ZHXHPEMSGWDXAG-SAIGFBBZSA-N 141827 US8921397, 69 D(2) dopamine receptor Homo sapiens 28.13 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141827&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675511 251911129 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277209 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)C#N InChI=1S/C29H33N3O2/c30-19-22-5-9-24(10-6-22)29(33)31-25-11-7-21(8-12-25)13-16-32-17-14-23(15-18-32)27-20-34-28-4-2-1-3-26(27)28/h1-6,9-10,20-21,23,25H,7-8,11-18H2,(H,31,33)/t21-,25- MOBMWPPSJIZIKV-OKDASEJXSA-N 141828 US8921397, 70 D(2) dopamine receptor Homo sapiens 15.19 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141828&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70673570 251911130 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277210 CC(C)(C)Oc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C32H42N2O3/c1-32(2,3)37-27-14-10-25(11-15-27)31(35)33-26-12-8-23(9-13-26)16-19-34-20-17-24(18-21-34)29-22-36-30-7-5-4-6-28(29)30/h4-7,10-11,14-15,22-24,26H,8-9,12-13,16-21H2,1-3H3,(H,33,35)/t23-,26- JNOKWZBEYVLXQJ-OJBMAJLDSA-N 141829 US8921397, 71 D(2) dopamine receptor Homo sapiens 168.26 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141829&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675512 251911131 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277211 CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3coc4ccccc34)CC2)CC1 InChI=1S/C30H44N2O3/c1-34-26-12-8-23(9-13-26)20-30(33)31-25-10-6-22(7-11-25)14-17-32-18-15-24(16-19-32)28-21-35-29-5-3-2-4-27(28)29/h2-5,21-26H,6-20H2,1H3,(H,31,33)/t22-,23-,25-,26- AKOUANOAMJNPBZ-GJIFKWMDSA-N 141830 US8921397, 72 D(2) dopamine receptor Homo sapiens 67.41 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141830&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675513 251911132 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277212 O=C(NC1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc2ncccc2c1 InChI=1S/C31H35N3O2/c35-31(25-9-12-29-24(20-25)4-3-16-32-29)33-26-10-7-22(8-11-26)13-17-34-18-14-23(15-19-34)28-21-36-30-6-2-1-5-27(28)30/h1-6,9,12,16,20-23,26H,7-8,10-11,13-15,17-19H2,(H,33,35)/t22-,26? JWZQTYLGRLCMJW-VYZLDGAWSA-N 141831 US8921397, 73 D(2) dopamine receptor Homo sapiens 102.85 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141831&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675529 251911133 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277213 O=C(Cc1ccc2OCOc2c1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C30H36N2O4/c33-30(18-22-7-10-28-29(17-22)36-20-35-28)31-24-8-5-21(6-9-24)11-14-32-15-12-23(13-16-32)26-19-34-27-4-2-1-3-25(26)27/h1-4,7,10,17,19,21,23-24H,5-6,8-9,11-16,18,20H2,(H,31,33)/t21-,24- FETIOVWFCXVZTM-SAIGFBBZSA-N 141832 US8921397, 74 D(2) dopamine receptor Homo sapiens 92.47 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141832&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675530 251911134 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277214 CS(=O)(=O)c1ccc(s1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C27H34N2O4S2/c1-35(31,32)26-11-10-25(34-26)27(30)28-21-8-6-19(7-9-21)12-15-29-16-13-20(14-17-29)23-18-33-24-5-3-2-4-22(23)24/h2-5,10-11,18-21H,6-9,12-17H2,1H3,(H,28,30)/t19-,21- SRZBALGZTDLNCE-XUTJKUGGSA-N 141833 US8921397, 75 D(2) dopamine receptor Homo sapiens 60.84 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675531 251911135 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277215 O=C(CC1COC1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C26H36N2O3/c29-26(15-20-16-30-17-20)27-22-7-5-19(6-8-22)9-12-28-13-10-21(11-14-28)24-18-31-25-4-2-1-3-23(24)25/h1-4,18-22H,5-17H2,(H,27,29)/t19-,22- HOMQYYYMDXLYHT-XYWHTSSQSA-N 141834 US8921397, 76 D(2) dopamine receptor Homo sapiens 34.19 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141834&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675532 251911136 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277216 CC(C)(C)C1CCC(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C32H48N2O2/c1-32(2,3)26-12-10-25(11-13-26)31(35)33-27-14-8-23(9-15-27)16-19-34-20-17-24(18-21-34)29-22-36-30-7-5-4-6-28(29)30/h4-7,22-27H,8-21H2,1-3H3,(H,33,35)/t23-,25?,26?,27- UPDGYYYUTBGSJZ-IALBEUSZSA-N 141835 US8921397, 77 D(2) dopamine receptor Homo sapiens 344.55 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675571 251911137 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277217 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)C12CC3CC(CC(C3)C1)C2 InChI=1S/C32H44N2O2/c35-31(32-18-23-15-24(19-32)17-25(16-23)20-32)33-27-7-5-22(6-8-27)9-12-34-13-10-26(11-14-34)29-21-36-30-4-2-1-3-28(29)30/h1-4,21-27H,5-20H2,(H,33,35)/t22-,23?,24?,25?,27-,32? INZTWDPMSQSIHC-WXKZGDQPSA-N 141836 US8921397, 78 D(2) dopamine receptor Homo sapiens 129.19 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675548 251911138 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277218 FC(F)(F)C1CCC(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C29H39F3N2O2/c30-29(31,32)23-9-7-22(8-10-23)28(35)33-24-11-5-20(6-12-24)13-16-34-17-14-21(15-18-34)26-19-36-27-4-2-1-3-25(26)27/h1-4,19-24H,5-18H2,(H,33,35)/t20-,22?,23?,24- GPUXMPIFNAGRSF-XPEDOLEQSA-N 141837 US8921397, 79 D(2) dopamine receptor Homo sapiens 72.97 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141837&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675549 251911139 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277219 CC(C)Cc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C32H42N2O2/c1-23(2)21-25-7-11-27(12-8-25)32(35)33-28-13-9-24(10-14-28)15-18-34-19-16-26(17-20-34)30-22-36-31-6-4-3-5-29(30)31/h3-8,11-12,22-24,26,28H,9-10,13-21H2,1-2H3,(H,33,35)/t24-,28- HRSJSQHPKLXGDX-XBTDCMMSSA-N 141838 US8921397, 80 D(2) dopamine receptor Homo sapiens 291.61 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675550 251911140 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277220 CCc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C30H38N2O2/c1-2-22-7-11-25(12-8-22)30(33)31-26-13-9-23(10-14-26)15-18-32-19-16-24(17-20-32)28-21-34-29-6-4-3-5-27(28)29/h3-8,11-12,21,23-24,26H,2,9-10,13-20H2,1H3,(H,31,33)/t23-,26- DPJONOPQJUKYRM-OJBMAJLDSA-N 141839 US8921397, 81 D(2) dopamine receptor Homo sapiens 204.42 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675551 251911141 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277221 CC(C)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C31H40N2O2/c1-22(2)24-9-11-26(12-10-24)31(34)32-27-13-7-23(8-14-27)15-18-33-19-16-25(17-20-33)29-21-35-30-6-4-3-5-28(29)30/h3-6,9-12,21-23,25,27H,7-8,13-20H2,1-2H3,(H,32,34)/t23-,27- VPCKUMFPILIIDI-JIBACQESSA-N 141841 US8921397, 83 D(2) dopamine receptor Homo sapiens 401.84 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141841&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675572 251911143 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277222 O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc(cc1)C1CC1 InChI=1S/C31H38N2O2/c34-31(26-11-9-24(10-12-26)23-7-8-23)32-27-13-5-22(6-14-27)15-18-33-19-16-25(17-20-33)29-21-35-30-4-2-1-3-28(29)30/h1-4,9-12,21-23,25,27H,5-8,13-20H2,(H,32,34)/t22-,27- JPCGHQPCQSFZIF-MGFGWZDJSA-N 141842 US8921397, 84 D(2) dopamine receptor Homo sapiens 355.25 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675573 251911144 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277223 O=C(Cc1noc2ccccc12)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C30H35N3O3/c34-30(19-27-25-6-2-4-8-29(25)36-32-27)31-23-11-9-21(10-12-23)13-16-33-17-14-22(15-18-33)26-20-35-28-7-3-1-5-24(26)28/h1-8,20-23H,9-19H2,(H,31,34)/t21-,23- YLZYYZWHNZPVBP-AFARHQOCSA-N 141843 US8921397, 85 D(2) dopamine receptor Homo sapiens 244.83 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675574 251911145 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277224 CS(=O)(=O)c1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C29H36N2O4S/c1-36(33,34)25-12-8-23(9-13-25)29(32)30-24-10-6-21(7-11-24)14-17-31-18-15-22(16-19-31)27-20-35-28-5-3-2-4-26(27)28/h2-5,8-9,12-13,20-22,24H,6-7,10-11,14-19H2,1H3,(H,30,32)/t21-,24- BKGCONUTJMJLTI-SAIGFBBZSA-N 141844 US8921397, 86 D(2) dopamine receptor Homo sapiens 79.51 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675575 251911146 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277151 FC(F)(F)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C24H31F3N2O2/c25-24(26,27)15-23(30)28-19-7-5-17(6-8-19)9-12-29-13-10-18(11-14-29)21-16-31-22-4-2-1-3-20(21)22/h1-4,16-19H,5-15H2,(H,28,30)/t17-,19- YBIAFKASHSKZAI-UAPYVXQJSA-N 141770 US8921397, 12 D(2) dopamine receptor Homo sapiens 42.66 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70674942 251911072 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277225 Clc1ccc(C(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3coc4ccccc34)CC2)c(Cl)c1 InChI=1S/C28H32Cl2N2O2/c29-21-7-10-24(26(30)17-21)28(33)31-22-8-5-19(6-9-22)11-14-32-15-12-20(13-16-32)25-18-34-27-4-2-1-3-23(25)27/h1-4,7,10,17-20,22H,5-6,8-9,11-16H2,(H,31,33)/t19-,22- XESYYKHMJOWEPL-XYWHTSSQSA-N 141845 US8921397, 87 D(2) dopamine receptor Homo sapiens 38.17 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675607 251911147 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 277226 CC(C)(C)c1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 InChI=1S/C31H42N2O3S/c1-31(2,3)25-10-14-27(15-11-25)37(34,35)32-26-12-8-23(9-13-26)16-19-33-20-17-24(18-21-33)29-22-36-30-7-5-4-6-28(29)30/h4-7,10-11,14-15,22-24,26,32H,8-9,12-13,16-21H2,1-3H3/t23-,26- ZRDGENRQQWKSHG-OJBMAJLDSA-N 141846 US8921397, 88 D(2) dopamine receptor Homo sapiens 70.03 US Patent 10.7270/Q2VQ31C3 aid1800826 US8921397 Rodriguez Sarmiento, RM; Wichmann, J Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=141846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=141846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70675590 251911148 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 326501 CS(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCC(CC3)C(O)=N)c2c1 InChI=1S/C22H27N3O3S2/c1-30(27,28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26) BQDBKDMTIJBJLA-UHFFFAOYSA-N 179867 US11147820, Compound Metopimazine::US9132134, Metopimazine (NG101) D(2) dopamine receptor Homo sapiens 0.07 US Patent 10.7270/Q2GM8631 aid1801610 US9132134 De Colle, C; Pasricha, P Neurogastrx, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 26388 313084695 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 326502 CS(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCC(CC3)C(O)=O)c2c1 InChI=1S/C22H26N2O4S2/c1-30(27,28)17-7-8-21-19(15-17)24(18-5-2-3-6-20(18)29-21)12-4-11-23-13-9-16(10-14-23)22(25)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H,25,26) PWQSSAWBTAKELO-UHFFFAOYSA-N 179868 US11147820, Compound Metopimazine acid::US9132134, Metopimazine-Acid (NG102) D(2) dopamine receptor Homo sapiens 14 US Patent 10.7270/Q2GM8631 aid1801610 US9132134 De Colle, C; Pasricha, P Neurogastrx, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179868&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46782362 313084696 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 326503 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Homo sapiens 1.3 US Patent 10.7270/Q2GM8631 aid1801610 US9132134 De Colle, C; Pasricha, P Neurogastrx, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 326504 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Homo sapiens 64 US Patent 10.7270/Q2GM8631 aid1801610 US9132134 De Colle, C; Pasricha, P Neurogastrx, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334893 Clc1cccc(N2CCCN(CCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-1-5-21(23(19)25)28-12-2-10-27(13-14-28)11-3-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1,4-6,8,16H,2-3,7,9-15H2,(H,26,29) CWVVNHIKQCMQOH-UHFFFAOYSA-N 185677 UNC10000003::US9156822, 1 D(2) dopamine receptor Homo sapiens 8.3 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185677&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597937 315516368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334894 Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30) NGCKUAWDNUFNBB-UHFFFAOYSA-N 50395587 CHEMBL2165126::UNC10000006::US9156822, 2 D(2) dopamine receptor Homo sapiens 3.6 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597938 163344611 CHEMBL2165126 ZINC72318112 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334895 Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4n3)CC2)c1Cl InChI=1S/C23H28Cl2N4O2/c24-18-5-3-6-19(22(18)25)29-13-4-12-28(14-15-29)11-1-2-16-31-21-10-8-17-7-9-20(30)26-23(17)27-21/h3,5-6,8,10H,1-2,4,7,9,11-16H2,(H,26,27,30) JQSRFMXTGAVHIR-UHFFFAOYSA-N 50395569 CHEMBL2165119::UNC10099975::US9156822, 3 or UNC9975 D(2) dopamine receptor Homo sapiens 1.2 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56593482 163344593 CHEMBL2165119 ZINC72318111 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334896 Clc1cccc(N2CCCN(CCCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C24H27Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-10,17H,1-2,4,11-16H2,(H,27,30) HWTAZRRAKMJTGD-UHFFFAOYSA-N 50395568 CHEMBL2165120::UNC10099978::US9156822, 4 D(2) dopamine receptor Homo sapiens 3.4 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559588 163344592 CHEMBL2165120 ZINC95552147 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334897 Clc1cccc(N2CCCN(CCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-20-4-1-5-21(22(20)25)28-12-2-10-27(13-14-28)11-3-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h1,4-7,16H,2-3,8-15H2,(H,26,29) IHIMEHQDIJSRNN-UHFFFAOYSA-N 50395570 CHEMBL2165118::UNC10099983::US9156822, 5 D(2) dopamine receptor Homo sapiens 5.7 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559587 163344594 CHEMBL2165118 ZINC95557184 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334898 Clc1cccc(N2CCCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C24H29Cl2N3O2/c25-21-5-3-6-22(23(21)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-8-7-18-9-10-27-24(30)20(18)17-19/h3,5-8,17H,1-2,4,9-16H2,(H,27,30) HDTSSQFZHKNWGP-UHFFFAOYSA-N 185678 UNC10099984::US9156822, 6 D(2) dopamine receptor Homo sapiens 4.6 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598210 315516369 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334899 Clc1cccc(N2CCCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C22H25Cl2N3OS/c23-18-5-3-6-20(22(18)24)27-11-4-10-26(12-13-27)9-1-2-14-28-17-7-8-21-19(15-17)25-16-29-21/h3,5-8,15-16H,1-2,4,9-14H2 WYMJRTXYUOPUMF-UHFFFAOYSA-N 50395574 CHEMBL2165114::UNC10099992::US9156822, 7 D(2) dopamine receptor Homo sapiens 18 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598070 163344598 CHEMBL2165114 ZINC95553219 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334900 Clc1cccc(N2CCCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C21H23Cl2N3OS/c22-17-4-1-5-19(21(17)23)26-10-2-8-25(11-12-26)9-3-13-27-16-6-7-20-18(14-16)24-15-28-20/h1,4-7,14-15H,2-3,8-13H2 QVTRXUDCQFWWGV-UHFFFAOYSA-N 50395575 CHEMBL2165140::UNC10099996::US9156822, 8 D(2) dopamine receptor Homo sapiens 20 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598071 163344599 CHEMBL2165140 ZINC95553137 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334901 COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C25H33N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-9,11,19H,4-6,10,12-18H2,1H3,(H,26,29) FAKVJGDVZFHZPG-UHFFFAOYSA-N 185679 UNC10107953::US9156822, 9 D(2) dopamine receptor Homo sapiens 4 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598072 315516370 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334902 COc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C25H31N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-12,19H,4-6,13-18H2,1H3,(H,26,29) WASBJZGHAFSXQF-UHFFFAOYSA-N 185680 UNC10107954::US9156822, 10 D(2) dopamine receptor Homo sapiens 2.1 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225821 315516371 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334903 COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C24H32N4O3/c1-30-21-8-3-2-7-20(21)28-15-6-14-27(16-17-28)13-4-5-18-31-23-12-10-19-9-11-22(29)25-24(19)26-23/h2-3,7-8,10,12H,4-6,9,11,13-18H2,1H3,(H,25,26,29) GWOIEWDIINTVPJ-UHFFFAOYSA-N 185681 UNC10107955::US9156822, 11 D(2) dopamine receptor Homo sapiens 5.7 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185681&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598877 315516372 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334904 CCOc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C26H35N3O3/c1-2-31-25-9-4-3-8-24(25)29-16-7-15-28(17-18-29)14-5-6-19-32-22-12-10-21-11-13-26(30)27-23(21)20-22/h3-4,8-10,12,20H,2,5-7,11,13-19H2,1H3,(H,27,30) LSPRXYHHXZGNPI-UHFFFAOYSA-N 185682 UNC10107958::US9156822, 12 D(2) dopamine receptor Homo sapiens 4.1 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185682&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598878 315516373 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334905 CCOc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C25H34N4O3/c1-2-31-22-9-4-3-8-21(22)29-16-7-15-28(17-18-29)14-5-6-19-32-24-13-11-20-10-12-23(30)26-25(20)27-24/h3-4,8-9,11,13H,2,5-7,10,12,14-19H2,1H3,(H,26,27,30) LVVVBEVBRWMYII-UHFFFAOYSA-N 185683 UNC10107959::US9156822, 13 D(2) dopamine receptor Homo sapiens 4.4 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598073 315516374 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334906 CCOc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C26H33N3O3/c1-2-31-25-9-4-3-8-24(25)29-16-7-15-28(17-18-29)14-5-6-19-32-22-12-10-21-11-13-26(30)27-23(21)20-22/h3-4,8-13,20H,2,5-7,14-19H2,1H3,(H,27,30) UAILOOIRJOOOAV-UHFFFAOYSA-N 185684 UNC10107962::US9156822, 14 D(2) dopamine receptor Homo sapiens 3.6 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225822 315516375 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334907 Clc1cccc(N2CCCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C23H25Cl2N3O2/c24-19-4-1-5-21(23(19)25)28-12-2-10-27(13-14-28)11-3-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1,4-9,16H,2-3,10-15H2,(H,26,29) WXHPNHJKGIFCOC-UHFFFAOYSA-N 185685 UNC10107966::US9156822, 15 D(2) dopamine receptor Homo sapiens 3.4 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76372146 315516376 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334908 CC(C)Oc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C27H37N3O3/c1-21(2)33-26-9-4-3-8-25(26)30-16-7-15-29(17-18-30)14-5-6-19-32-23-12-10-22-11-13-27(31)28-24(22)20-23/h3-4,8-10,12,20-21H,5-7,11,13-19H2,1-2H3,(H,28,31) RJQFZMPQCFFXTK-UHFFFAOYSA-N 185686 UNC10107967::US9156822, 16 D(2) dopamine receptor Homo sapiens 0.87 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598075 315516377 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334909 CC(C)Oc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C26H36N4O3/c1-20(2)33-23-9-4-3-8-22(23)30-16-7-15-29(17-18-30)14-5-6-19-32-25-13-11-21-10-12-24(31)27-26(21)28-25/h3-4,8-9,11,13,20H,5-7,10,12,14-19H2,1-2H3,(H,27,28,31) FRQVGTOODSSJIY-UHFFFAOYSA-N 185687 UNC10107968::US9156822, 17 D(2) dopamine receptor Homo sapiens 1.29 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185687&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66633659 315516378 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334910 CC(C)Oc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C27H35N3O3/c1-21(2)33-26-9-4-3-8-25(26)30-16-7-15-29(17-18-30)14-5-6-19-32-23-12-10-22-11-13-27(31)28-24(22)20-23/h3-4,8-13,20-21H,5-7,14-19H2,1-2H3,(H,28,31) OKJIXAFKUUQQCX-UHFFFAOYSA-N 185688 UNC10107969::US9156822, 18 D(2) dopamine receptor Homo sapiens 0.93 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185688&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76372506 315516379 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334911 Clc1cccc(N2CCCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O2/c22-16-4-1-5-19(20(16)23)27-10-2-8-26(11-12-27)9-3-13-29-15-6-7-17-18(14-15)25-21(28)24-17/h1,4-7,14H,2-3,8-13H2,(H2,24,25,28) ARPHSPFYEOAIMK-UHFFFAOYSA-N 185689 UNC10108005::US9156822, 19 D(2) dopamine receptor Homo sapiens 4.5 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185689&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225823 315516380 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334912 Clc1cccc(N2CCN(CCCOc3ccc4cn[nH]c4c3)CC2)c1Cl InChI=1S/C20H22Cl2N4O/c21-17-3-1-4-19(20(17)22)26-10-8-25(9-11-26)7-2-12-27-16-6-5-15-14-23-24-18(15)13-16/h1,3-6,13-14H,2,7-12H2,(H,23,24) WOXYKTMEOIXZAQ-UHFFFAOYSA-N 50395572 CHEMBL2165116::UNC10099976::US9156822, 20 D(2) dopamine receptor Homo sapiens 104 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597939 163344596 CHEMBL2165116 ZINC95553616 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334913 Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C22H24Cl2N2OS/c23-19-5-3-4-18(22(19)24)16-8-11-26(12-9-16)10-1-2-13-27-17-6-7-21-20(14-17)25-15-28-21/h3-7,14-16H,1-2,8-13H2 DXXXGJIMFKZHRL-UHFFFAOYSA-N 50395578 CHEMBL2165137::UNC10099993::US9156822, 21 D(2) dopamine receptor Homo sapiens 42 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597090 163344602 CHEMBL2165137 ZINC95557182 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334914 Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C21H22Cl2N2OS/c22-18-4-1-3-17(21(18)23)15-7-10-25(11-8-15)9-2-12-26-16-5-6-20-19(13-16)24-14-27-20/h1,3-6,13-15H,2,7-12H2 URYZTMIOHYGTNJ-UHFFFAOYSA-N 50395577 CHEMBL2165138::UNC10099994::US9156822, 22 D(2) dopamine receptor Homo sapiens 75 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599142 163344601 CHEMBL2165138 ZINC72318113 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334915 Clc1cccc(N2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C20H21Cl2N3OS/c21-16-3-1-4-18(20(16)22)25-10-8-24(9-11-25)7-2-12-26-15-5-6-19-17(13-15)23-14-27-19/h1,3-6,13-14H,2,7-12H2 VBHBKXBUHHJVBZ-UHFFFAOYSA-N 50395576 CHEMBL2165139::UNC10099995::US9156822, 23 D(2) dopamine receptor Homo sapiens 30 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599143 163344600 CHEMBL2165139 ZINC95553637 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334916 Clc1cccc(C2CCN(CCCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C22H25Cl2N3O2/c23-18-5-3-4-17(21(18)24)15-8-11-27(12-9-15)10-1-2-13-29-16-6-7-19-20(14-16)26-22(28)25-19/h3-7,14-15H,1-2,8-13H2,(H2,25,26,28) JEZQFKLGYQTDDK-UHFFFAOYSA-N 50395573 CHEMBL2165115::UNC10108006::US9156822, 24 D(2) dopamine receptor Homo sapiens 10.9 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599144 163344597 CHEMBL2165115 ZINC95553126 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334917 Clc1cccc(N2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-20-4-3-5-21(22(20)25)28-13-11-27(12-14-28)10-1-2-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h3-7,16H,1-2,8-15H2,(H,26,29) VBFRZHYHMOZIEU-UHFFFAOYSA-N 50395582 CHEMBL2165133::UNC10000004::US9156822, 25 D(2) dopamine receptor Homo sapiens 18 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599145 163344606 CHEMBL2165133 ZINC95552743 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334918 Clc1cccc(N2CCN(CC3CCC(COc4ccc5CCC(=O)Nc5c4)CC3)CC2)c1Cl InChI=1S/C27H33Cl2N3O2/c28-23-2-1-3-25(27(23)29)32-14-12-31(13-15-32)17-19-4-6-20(7-5-19)18-34-22-10-8-21-9-11-26(33)30-24(21)16-22/h1-3,8,10,16,19-20H,4-7,9,11-15,17-18H2,(H,30,33) CRARFJICFRVCGK-UHFFFAOYSA-N 185690 UNC10000007::US9156822, 26 D(2) dopamine receptor Homo sapiens 145 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185690&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599146 315516381 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334919 Clc1cccc(N2CCN(CC#CCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H23Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,7,9-15H2,(H,26,29) FNZOOYYZKQCPEG-UHFFFAOYSA-N 50395585 CHEMBL2165129::UNC10000009::US9156822, 27 D(2) dopamine receptor Homo sapiens 1004 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395585&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599147 163344609 CHEMBL2165129 ZINC95554397 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334920 Clc1cccc(N2CCN(CCCCOc3ccc4cn[nH]c4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-18-4-3-5-20(21(18)23)27-11-9-26(10-12-27)8-1-2-13-28-17-7-6-16-15-24-25-19(16)14-17/h3-7,14-15H,1-2,8-13H2,(H,24,25) IKOXHMZXTCWMQE-UHFFFAOYSA-N 50395581 CHEMBL2165134::UNC10000010::US9156822, 28 D(2) dopamine receptor Homo sapiens 66 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597091 163344605 CHEMBL2165134 ZINC95552916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334921 Clc1cccc(N2CCN(C\C=C\COc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H25Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1-6,8,16H,7,9-15H2,(H,26,29)/b2-1+ SKGKYEPRBPJYRW-OWOJBTEDSA-N 185691 UNC10000011::US9156822, 29 D(2) dopamine receptor Homo sapiens 15 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185691&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66633745 315516382 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334922 Clc1cccc(N2CCN(Cc3cccc(Oc4ccc5CCC(=O)Nc5c4)c3)CC2)c1Cl InChI=1S/C26H25Cl2N3O2/c27-22-5-2-6-24(26(22)28)31-13-11-30(12-14-31)17-18-3-1-4-20(15-18)33-21-9-7-19-8-10-25(32)29-23(19)16-21/h1-7,9,15-16H,8,10-14,17H2,(H,29,32) PULGLQOWTRCVQB-UHFFFAOYSA-N 50395584 CHEMBL2165131::UNC10099972::US9156822, 30 D(2) dopamine receptor Homo sapiens 113 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395584&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559506 163344608 CHEMBL2165131 ZINC95552101 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334923 Clc1cccc(N2CCN(Cc3ccc(Oc4ccc5CCC(=O)Nc5c4)cc3)CC2)c1Cl InChI=1S/C26H25Cl2N3O2/c27-22-2-1-3-24(26(22)28)31-14-12-30(13-15-31)17-18-4-8-20(9-5-18)33-21-10-6-19-7-11-25(32)29-23(19)16-21/h1-6,8-10,16H,7,11-15,17H2,(H,29,32) MCIWPVPYVLZFFO-UHFFFAOYSA-N 50395583 CHEMBL2165132::UNC10099973::US9156822, 31 D(2) dopamine receptor Homo sapiens 108 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559507 163344607 CHEMBL2165132 ZINC95556448 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334924 Clc1cccc(N2CCN(CCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C22H25Cl2N3O2/c23-19-3-1-4-20(21(19)24)27-12-10-26(11-13-27)9-2-14-29-17-6-5-16-7-8-25-22(28)18(16)15-17/h1,3-6,15H,2,7-14H2,(H,25,28) QXPBZNWEPREKHB-UHFFFAOYSA-N 50395571 CHEMBL2165117::UNC10099981::US10501452, Compound A::US9156822, 32 D(2) dopamine receptor Homo sapiens 18 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597092 163344595 CHEMBL2165117 ZINC95555707 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334925 Clc1cccc(C2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C24H28Cl2N2O2/c25-22-5-3-4-20(23(22)26)18-9-13-28(14-10-18)12-1-2-15-30-19-7-6-17-8-11-27-24(29)21(17)16-19/h3-7,16,18H,1-2,8-15H2,(H,27,29) HVXBMABYUWVXDA-UHFFFAOYSA-N 185692 UNC10099985::US9156822, 33 D(2) dopamine receptor Homo sapiens 20 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597093 315516383 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334926 Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C20H22Cl2N4O2/c21-15-3-1-4-18(19(15)22)26-10-8-25(9-11-26)7-2-12-28-14-5-6-16-17(13-14)24-20(27)23-16/h1,3-6,13H,2,7-12H2,(H2,23,24,27) NKDQNOFCLUVBIY-UHFFFAOYSA-N 185693 UNC10099988::US9156822, 34 D(2) dopamine receptor Homo sapiens 25 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225824 315516384 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334927 Clc1cccc(N2CCN(CCCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O2/c22-16-4-3-5-19(20(16)23)27-11-9-26(10-12-27)8-1-2-13-29-15-6-7-17-18(14-15)25-21(28)24-17/h3-7,14H,1-2,8-13H2,(H2,24,25,28) LROJLXGQKUBROL-UHFFFAOYSA-N 50395580 CHEMBL2165135::UNC10099990::US9156822, 35 D(2) dopamine receptor Homo sapiens 15 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597095 163344604 CHEMBL2165135 ZINC95556802 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334928 Clc1cccc(N2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C21H23Cl2N3OS/c22-17-4-3-5-19(21(17)23)26-11-9-25(10-12-26)8-1-2-13-27-16-6-7-20-18(14-16)24-15-28-20/h3-7,14-15H,1-2,8-13H2 JBKITGSPOFFGJB-UHFFFAOYSA-N 50395579 CHEMBL2165136::UNC10099991::US9156822, 36 D(2) dopamine receptor Homo sapiens 17 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597225 163344603 CHEMBL2165136 ZINC95553695 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334929 COc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C23H30N4O3/c1-29-20-7-3-2-6-19(20)27-15-13-26(14-16-27)12-4-5-17-30-22-11-9-18-8-10-21(28)24-23(18)25-22/h2-3,6-7,9,11H,4-5,8,10,12-17H2,1H3,(H,24,25,28) DTVAIMZRGJKGPN-UHFFFAOYSA-N 185694 UNC10107957::US9156822, 37 D(2) dopamine receptor Homo sapiens 1.7 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185694&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597226 315516385 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334930 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4NC(=O)COc34)cc2N1 InChI=1S/C25H30N4O4/c30-23-9-7-18-6-8-19(16-21(18)27-23)32-15-2-1-10-28-11-13-29(14-12-28)22-5-3-4-20-25(22)33-17-24(31)26-20/h3-6,8,16H,1-2,7,9-15,17H2,(H,26,31)(H,27,30) IPAFOBZCTHBJBT-UHFFFAOYSA-N 185695 UNC10108010::US9156822, 38 D(2) dopamine receptor Homo sapiens 0.47 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185695&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597940 315516386 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334931 COc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C24H31N3O3/c1-29-23-7-3-2-6-22(23)27-15-13-26(14-16-27)12-4-5-17-30-20-10-8-19-9-11-24(28)25-21(19)18-20/h2-3,6-8,10,18H,4-5,9,11-17H2,1H3,(H,25,28) HVSUPPZVIPTMEM-UHFFFAOYSA-N 50349866 CHEMBL160296::CHEMBL1813590::UNC10108016::US9156822, 39 D(2) dopamine receptor Homo sapiens 0.32 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50349866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50349866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692886 136356552 CHEMBL160296CHEMBL1813590 ZINC27725864 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334932 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)cc2N1 InChI=1S/C25H31N3O4/c29-24-9-7-19-6-8-20(18-21(19)26-24)30-15-2-1-10-27-11-13-28(14-12-27)22-4-3-5-23-25(22)32-17-16-31-23/h3-6,8,18H,1-2,7,9-17H2,(H,26,29) AMAZFBCTWBJQKF-UHFFFAOYSA-N 185696 UNC10108017::US9156822, 40 D(2) dopamine receptor Homo sapiens 0.3 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185696&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597227 315516387 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334933 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)nc2N1 InChI=1S/C24H30N4O4/c29-21-8-6-18-7-9-22(26-24(18)25-21)31-15-2-1-10-27-11-13-28(14-12-27)19-4-3-5-20-23(19)32-17-16-30-20/h3-5,7,9H,1-2,6,8,10-17H2,(H,25,26,29) NENVXZKTDUNSBM-UHFFFAOYSA-N 185697 UNC10108018::US9156822, 41 D(2) dopamine receptor Homo sapiens 0.45 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21073553 315516388 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334934 O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)cc2[nH]1 InChI=1S/C25H29N3O4/c29-24-9-7-19-6-8-20(18-21(19)26-24)30-15-2-1-10-27-11-13-28(14-12-27)22-4-3-5-23-25(22)32-17-16-31-23/h3-9,18H,1-2,10-17H2,(H,26,29) WKXGCJMHUWZCIC-UHFFFAOYSA-N 185698 UNC10108019::US9156822, 42 D(2) dopamine receptor Homo sapiens 0.4 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77156277 315516389 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334935 CC(=O)Nc1cc(OCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc1C InChI=1S/C23H29Cl2N3O2/c1-17-8-9-19(16-21(17)26-18(2)29)30-15-4-3-10-27-11-13-28(14-12-27)22-7-5-6-20(24)23(22)25/h5-9,16H,3-4,10-15H2,1-2H3,(H,26,29) PYODBBFAXCRGHN-UHFFFAOYSA-N 185699 UNC10108049::US9156822, 43 D(2) dopamine receptor Homo sapiens 72 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185699&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597942 315516390 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334936 Clc1cccc(N2CCCN(CCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-1-5-21(23(19)25)28-12-2-10-27(13-14-28)11-3-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1,4-6,8,16H,2-3,7,9-15H2,(H,26,29) CWVVNHIKQCMQOH-UHFFFAOYSA-N 185677 UNC10000003::US9156822, 1 D(2) dopamine receptor Homo sapiens 6.1 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185677&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597937 315516368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334937 Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30) NGCKUAWDNUFNBB-UHFFFAOYSA-N 50395587 CHEMBL2165126::UNC10000006::US9156822, 2 D(2) dopamine receptor Homo sapiens 126 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597938 163344611 CHEMBL2165126 ZINC72318112 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334938 Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4n3)CC2)c1Cl InChI=1S/C23H28Cl2N4O2/c24-18-5-3-6-19(22(18)25)29-13-4-12-28(14-15-29)11-1-2-16-31-21-10-8-17-7-9-20(30)26-23(17)27-21/h3,5-6,8,10H,1-2,4,7,9,11-16H2,(H,26,27,30) JQSRFMXTGAVHIR-UHFFFAOYSA-N 50395569 CHEMBL2165119::UNC10099975::US9156822, 3 or UNC9975 D(2) dopamine receptor Homo sapiens 13 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56593482 163344593 CHEMBL2165119 ZINC72318111 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334939 Clc1cccc(N2CCCN(CCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-20-4-1-5-21(22(20)25)28-12-2-10-27(13-14-28)11-3-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h1,4-7,16H,2-3,8-15H2,(H,26,29) IHIMEHQDIJSRNN-UHFFFAOYSA-N 50395570 CHEMBL2165118::UNC10099983::US9156822, 5 D(2) dopamine receptor Homo sapiens 5.6 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559587 163344594 CHEMBL2165118 ZINC95557184 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334940 Clc1cccc(N2CCCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C24H29Cl2N3O2/c25-21-5-3-6-22(23(21)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-8-7-18-9-10-27-24(30)20(18)17-19/h3,5-8,17H,1-2,4,9-16H2,(H,27,30) HDTSSQFZHKNWGP-UHFFFAOYSA-N 185678 UNC10099984::US9156822, 6 D(2) dopamine receptor Homo sapiens 9870 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598210 315516369 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334941 Clc1cccc(N2CCCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C21H23Cl2N3OS/c22-17-4-1-5-19(21(17)23)26-10-2-8-25(11-12-26)9-3-13-27-16-6-7-20-18(14-16)24-15-28-20/h1,4-7,14-15H,2-3,8-13H2 QVTRXUDCQFWWGV-UHFFFAOYSA-N 50395575 CHEMBL2165140::UNC10099996::US9156822, 8 D(2) dopamine receptor Homo sapiens 348 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598071 163344599 CHEMBL2165140 ZINC95553137 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334942 COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C25H33N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-9,11,19H,4-6,10,12-18H2,1H3,(H,26,29) FAKVJGDVZFHZPG-UHFFFAOYSA-N 185679 UNC10107953::US9156822, 9 D(2) dopamine receptor Homo sapiens 163 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598072 315516370 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334943 COc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C25H31N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-12,19H,4-6,13-18H2,1H3,(H,26,29) WASBJZGHAFSXQF-UHFFFAOYSA-N 185680 UNC10107954::US9156822, 10 D(2) dopamine receptor Homo sapiens 306 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225821 315516371 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334944 COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C24H32N4O3/c1-30-21-8-3-2-7-20(21)28-15-6-14-27(16-17-28)13-4-5-18-31-23-12-10-19-9-11-22(29)25-24(19)26-23/h2-3,7-8,10,12H,4-6,9,11,13-18H2,1H3,(H,25,26,29) GWOIEWDIINTVPJ-UHFFFAOYSA-N 185681 UNC10107955::US9156822, 11 D(2) dopamine receptor Homo sapiens 222 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185681&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598877 315516372 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334945 CCOc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C26H33N3O3/c1-2-31-25-9-4-3-8-24(25)29-16-7-15-28(17-18-29)14-5-6-19-32-22-12-10-21-11-13-26(30)27-23(21)20-22/h3-4,8-13,20H,2,5-7,14-19H2,1H3,(H,27,30) UAILOOIRJOOOAV-UHFFFAOYSA-N 185684 UNC10107962::US9156822, 14 D(2) dopamine receptor Homo sapiens 27 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225822 315516375 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334946 Clc1cccc(N2CCCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C23H25Cl2N3O2/c24-19-4-1-5-21(23(19)25)28-12-2-10-27(13-14-28)11-3-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1,4-9,16H,2-3,10-15H2,(H,26,29) WXHPNHJKGIFCOC-UHFFFAOYSA-N 185685 UNC10107966::US9156822, 15 D(2) dopamine receptor Homo sapiens 13 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76372146 315516376 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334947 CC(C)Oc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C26H36N4O3/c1-20(2)33-23-9-4-3-8-22(23)30-16-7-15-29(17-18-30)14-5-6-19-32-25-13-11-21-10-12-24(31)27-26(21)28-25/h3-4,8-9,11,13,20H,5-7,10,12,14-19H2,1-2H3,(H,27,28,31) FRQVGTOODSSJIY-UHFFFAOYSA-N 185687 UNC10107968::US9156822, 17 D(2) dopamine receptor Homo sapiens 0.2 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185687&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66633659 315516378 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334948 CC(C)Oc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C27H35N3O3/c1-21(2)33-26-9-4-3-8-25(26)30-16-7-15-29(17-18-30)14-5-6-19-32-23-12-10-22-11-13-27(31)28-24(22)20-23/h3-4,8-13,20-21H,5-7,14-19H2,1-2H3,(H,28,31) OKJIXAFKUUQQCX-UHFFFAOYSA-N 185688 UNC10107969::US9156822, 18 D(2) dopamine receptor Homo sapiens 0.1 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185688&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76372506 315516379 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334949 Clc1cccc(N2CCN(CCCOc3ccc4cn[nH]c4c3)CC2)c1Cl InChI=1S/C20H22Cl2N4O/c21-17-3-1-4-19(20(17)22)26-10-8-25(9-11-26)7-2-12-27-16-6-5-15-14-23-24-18(15)13-16/h1,3-6,13-14H,2,7-12H2,(H,23,24) WOXYKTMEOIXZAQ-UHFFFAOYSA-N 50395572 CHEMBL2165116::UNC10099976::US9156822, 20 D(2) dopamine receptor Homo sapiens 9.7 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597939 163344596 CHEMBL2165116 ZINC95553616 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334950 Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C22H24Cl2N2OS/c23-19-5-3-4-18(22(19)24)16-8-11-26(12-9-16)10-1-2-13-27-17-6-7-21-20(14-17)25-15-28-21/h3-7,14-16H,1-2,8-13H2 DXXXGJIMFKZHRL-UHFFFAOYSA-N 50395578 CHEMBL2165137::UNC10099993::US9156822, 21 D(2) dopamine receptor Homo sapiens 21 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597090 163344602 CHEMBL2165137 ZINC95557182 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334951 Clc1cccc(N2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C20H21Cl2N3OS/c21-16-3-1-4-18(20(16)22)25-10-8-24(9-11-25)7-2-12-26-15-5-6-19-17(13-15)23-14-27-19/h1,3-6,13-14H,2,7-12H2 VBHBKXBUHHJVBZ-UHFFFAOYSA-N 50395576 CHEMBL2165139::UNC10099995::US9156822, 23 D(2) dopamine receptor Homo sapiens 9.8 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599143 163344600 CHEMBL2165139 ZINC95553637 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334952 Clc1cccc(N2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-20-4-3-5-21(22(20)25)28-13-11-27(12-14-28)10-1-2-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h3-7,16H,1-2,8-15H2,(H,26,29) VBFRZHYHMOZIEU-UHFFFAOYSA-N 50395582 CHEMBL2165133::UNC10000004::US9156822, 25 D(2) dopamine receptor Homo sapiens 3700 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599145 163344606 CHEMBL2165133 ZINC95552743 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334953 Clc1cccc(N2CCN(CC3CCC(COc4ccc5CCC(=O)Nc5c4)CC3)CC2)c1Cl InChI=1S/C27H33Cl2N3O2/c28-23-2-1-3-25(27(23)29)32-14-12-31(13-15-32)17-19-4-6-20(7-5-19)18-34-22-10-8-21-9-11-26(33)30-24(21)16-22/h1-3,8,10,16,19-20H,4-7,9,11-15,17-18H2,(H,30,33) CRARFJICFRVCGK-UHFFFAOYSA-N 185690 UNC10000007::US9156822, 26 D(2) dopamine receptor Homo sapiens 46000 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185690&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599146 315516381 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334954 Clc1cccc(N2CCN(CC#CCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H23Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,7,9-15H2,(H,26,29) FNZOOYYZKQCPEG-UHFFFAOYSA-N 50395585 CHEMBL2165129::UNC10000009::US9156822, 27 D(2) dopamine receptor Homo sapiens 1000 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395585&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599147 163344609 CHEMBL2165129 ZINC95554397 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334955 Clc1cccc(N2CCN(CCCCOc3ccc4cn[nH]c4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-18-4-3-5-20(21(18)23)27-11-9-26(10-12-27)8-1-2-13-28-17-7-6-16-15-24-25-19(16)14-17/h3-7,14-15H,1-2,8-13H2,(H,24,25) IKOXHMZXTCWMQE-UHFFFAOYSA-N 50395581 CHEMBL2165134::UNC10000010::US9156822, 28 D(2) dopamine receptor Homo sapiens 5.7 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597091 163344605 CHEMBL2165134 ZINC95552916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334956 Clc1cccc(N2CCN(Cc3ccc(Oc4ccc5CCC(=O)Nc5c4)cc3)CC2)c1Cl InChI=1S/C26H25Cl2N3O2/c27-22-2-1-3-24(26(22)28)31-14-12-30(13-15-31)17-18-4-8-20(9-5-18)33-21-10-6-19-7-11-25(32)29-23(19)16-21/h1-6,8-10,16H,7,11-15,17H2,(H,29,32) MCIWPVPYVLZFFO-UHFFFAOYSA-N 50395583 CHEMBL2165132::UNC10099973::US9156822, 31 D(2) dopamine receptor Homo sapiens 5.7 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559507 163344607 CHEMBL2165132 ZINC95556448 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334957 Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C20H22Cl2N4O2/c21-15-3-1-4-18(19(15)22)26-10-8-25(9-11-26)7-2-12-28-14-5-6-16-17(13-14)24-20(27)23-16/h1,3-6,13H,2,7-12H2,(H2,23,24,27) NKDQNOFCLUVBIY-UHFFFAOYSA-N 185693 UNC10099988::US9156822, 34 D(2) dopamine receptor Homo sapiens 512 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225824 315516384 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334958 COc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C23H30N4O3/c1-29-20-7-3-2-6-19(20)27-15-13-26(14-16-27)12-4-5-17-30-22-11-9-18-8-10-21(28)24-23(18)25-22/h2-3,6-7,9,11H,4-5,8,10,12-17H2,1H3,(H,24,25,28) DTVAIMZRGJKGPN-UHFFFAOYSA-N 185694 UNC10107957::US9156822, 37 D(2) dopamine receptor Homo sapiens 11 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185694&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597226 315516385 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334959 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4NC(=O)COc34)cc2N1 InChI=1S/C25H30N4O4/c30-23-9-7-18-6-8-19(16-21(18)27-23)32-15-2-1-10-28-11-13-29(14-12-28)22-5-3-4-20-25(22)33-17-24(31)26-20/h3-6,8,16H,1-2,7,9-15,17H2,(H,26,31)(H,27,30) IPAFOBZCTHBJBT-UHFFFAOYSA-N 185695 UNC10108010::US9156822, 38 D(2) dopamine receptor Homo sapiens 1.8 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185695&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597940 315516386 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334960 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)nc2N1 InChI=1S/C24H30N4O4/c29-21-8-6-18-7-9-22(26-24(18)25-21)31-15-2-1-10-27-11-13-28(14-12-27)19-4-3-5-20-23(19)32-17-16-30-20/h3-5,7,9H,1-2,6,8,10-17H2,(H,25,26,29) NENVXZKTDUNSBM-UHFFFAOYSA-N 185697 UNC10108018::US9156822, 41 D(2) dopamine receptor Homo sapiens 0.4 7.4 US Patent 10.7270/Q2H41Q6D aid1801735 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21073553 315516388 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334961 Clc1cccc(N2CCCN(CCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-1-5-21(23(19)25)28-12-2-10-27(13-14-28)11-3-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1,4-6,8,16H,2-3,7,9-15H2,(H,26,29) CWVVNHIKQCMQOH-UHFFFAOYSA-N 185677 UNC10000003::US9156822, 1 D(2) dopamine receptor Homo sapiens 3.1 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185677&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597937 315516368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334962 Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30) NGCKUAWDNUFNBB-UHFFFAOYSA-N 50395587 CHEMBL2165126::UNC10000006::US9156822, 2 D(2) dopamine receptor Homo sapiens 3.3 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597938 163344611 CHEMBL2165126 ZINC72318112 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334963 Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4n3)CC2)c1Cl InChI=1S/C23H28Cl2N4O2/c24-18-5-3-6-19(22(18)25)29-13-4-12-28(14-15-29)11-1-2-16-31-21-10-8-17-7-9-20(30)26-23(17)27-21/h3,5-6,8,10H,1-2,4,7,9,11-16H2,(H,26,27,30) JQSRFMXTGAVHIR-UHFFFAOYSA-N 50395569 CHEMBL2165119::UNC10099975::US9156822, 3 or UNC9975 D(2) dopamine receptor Homo sapiens 3.3 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56593482 163344593 CHEMBL2165119 ZINC72318111 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334964 Clc1cccc(N2CCCN(CCCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C24H27Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-10,17H,1-2,4,11-16H2,(H,27,30) HWTAZRRAKMJTGD-UHFFFAOYSA-N 50395568 CHEMBL2165120::UNC10099978::US9156822, 4 D(2) dopamine receptor Homo sapiens 2.8 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559588 163344592 CHEMBL2165120 ZINC95552147 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334965 Clc1cccc(N2CCCN(CCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-20-4-1-5-21(22(20)25)28-12-2-10-27(13-14-28)11-3-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h1,4-7,16H,2-3,8-15H2,(H,26,29) IHIMEHQDIJSRNN-UHFFFAOYSA-N 50395570 CHEMBL2165118::UNC10099983::US9156822, 5 D(2) dopamine receptor Homo sapiens 8 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559587 163344594 CHEMBL2165118 ZINC95557184 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334966 Clc1cccc(N2CCCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C24H29Cl2N3O2/c25-21-5-3-6-22(23(21)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-8-7-18-9-10-27-24(30)20(18)17-19/h3,5-8,17H,1-2,4,9-16H2,(H,27,30) HDTSSQFZHKNWGP-UHFFFAOYSA-N 185678 UNC10099984::US9156822, 6 D(2) dopamine receptor Homo sapiens 6.2 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598210 315516369 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334967 Clc1cccc(N2CCCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C22H25Cl2N3OS/c23-18-5-3-6-20(22(18)24)27-11-4-10-26(12-13-27)9-1-2-14-28-17-7-8-21-19(15-17)25-16-29-21/h3,5-8,15-16H,1-2,4,9-14H2 WYMJRTXYUOPUMF-UHFFFAOYSA-N 50395574 CHEMBL2165114::UNC10099992::US9156822, 7 D(2) dopamine receptor Homo sapiens 23 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598070 163344598 CHEMBL2165114 ZINC95553219 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334968 Clc1cccc(N2CCCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C21H23Cl2N3OS/c22-17-4-1-5-19(21(17)23)26-10-2-8-25(11-12-26)9-3-13-27-16-6-7-20-18(14-16)24-15-28-20/h1,4-7,14-15H,2-3,8-13H2 QVTRXUDCQFWWGV-UHFFFAOYSA-N 50395575 CHEMBL2165140::UNC10099996::US9156822, 8 D(2) dopamine receptor Homo sapiens 63 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598071 163344599 CHEMBL2165140 ZINC95553137 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334969 COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C25H33N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-9,11,19H,4-6,10,12-18H2,1H3,(H,26,29) FAKVJGDVZFHZPG-UHFFFAOYSA-N 185679 UNC10107953::US9156822, 9 D(2) dopamine receptor Homo sapiens 4.6 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598072 315516370 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334970 COc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C25H31N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-12,19H,4-6,13-18H2,1H3,(H,26,29) WASBJZGHAFSXQF-UHFFFAOYSA-N 185680 UNC10107954::US9156822, 10 D(2) dopamine receptor Homo sapiens 2.5 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225821 315516371 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334971 COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C24H32N4O3/c1-30-21-8-3-2-7-20(21)28-15-6-14-27(16-17-28)13-4-5-18-31-23-12-10-19-9-11-22(29)25-24(19)26-23/h2-3,7-8,10,12H,4-6,9,11,13-18H2,1H3,(H,25,26,29) GWOIEWDIINTVPJ-UHFFFAOYSA-N 185681 UNC10107955::US9156822, 11 D(2) dopamine receptor Homo sapiens 6.1 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185681&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598877 315516372 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334972 CCOc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C26H35N3O3/c1-2-31-25-9-4-3-8-24(25)29-16-7-15-28(17-18-29)14-5-6-19-32-22-12-10-21-11-13-26(30)27-23(21)20-22/h3-4,8-10,12,20H,2,5-7,11,13-19H2,1H3,(H,27,30) LSPRXYHHXZGNPI-UHFFFAOYSA-N 185682 UNC10107958::US9156822, 12 D(2) dopamine receptor Homo sapiens 4.3 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185682&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598878 315516373 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334973 CCOc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C25H34N4O3/c1-2-31-22-9-4-3-8-21(22)29-16-7-15-28(17-18-29)14-5-6-19-32-24-13-11-20-10-12-23(30)26-25(20)27-24/h3-4,8-9,11,13H,2,5-7,10,12,14-19H2,1H3,(H,26,27,30) LVVVBEVBRWMYII-UHFFFAOYSA-N 185683 UNC10107959::US9156822, 13 D(2) dopamine receptor Homo sapiens 4.0 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598073 315516374 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334974 CCOc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C26H33N3O3/c1-2-31-25-9-4-3-8-24(25)29-16-7-15-28(17-18-29)14-5-6-19-32-22-12-10-21-11-13-26(30)27-23(21)20-22/h3-4,8-13,20H,2,5-7,14-19H2,1H3,(H,27,30) UAILOOIRJOOOAV-UHFFFAOYSA-N 185684 UNC10107962::US9156822, 14 D(2) dopamine receptor Homo sapiens 4.8 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225822 315516375 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334975 Clc1cccc(N2CCCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C23H25Cl2N3O2/c24-19-4-1-5-21(23(19)25)28-12-2-10-27(13-14-28)11-3-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1,4-9,16H,2-3,10-15H2,(H,26,29) WXHPNHJKGIFCOC-UHFFFAOYSA-N 185685 UNC10107966::US9156822, 15 D(2) dopamine receptor Homo sapiens 2.2 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76372146 315516376 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334976 CC(C)Oc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C27H37N3O3/c1-21(2)33-26-9-4-3-8-25(26)30-16-7-15-29(17-18-30)14-5-6-19-32-23-12-10-22-11-13-27(31)28-24(22)20-23/h3-4,8-10,12,20-21H,5-7,11,13-19H2,1-2H3,(H,28,31) RJQFZMPQCFFXTK-UHFFFAOYSA-N 185686 UNC10107967::US9156822, 16 D(2) dopamine receptor Homo sapiens 4.2 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56598075 315516377 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334977 CC(C)Oc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C26H36N4O3/c1-20(2)33-23-9-4-3-8-22(23)30-16-7-15-29(17-18-30)14-5-6-19-32-25-13-11-21-10-12-24(31)27-26(21)28-25/h3-4,8-9,11,13,20H,5-7,10,12,14-19H2,1-2H3,(H,27,28,31) FRQVGTOODSSJIY-UHFFFAOYSA-N 185687 UNC10107968::US9156822, 17 D(2) dopamine receptor Homo sapiens 4.6 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185687&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66633659 315516378 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334978 CC(C)Oc1ccccc1N1CCCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1 InChI=1S/C27H35N3O3/c1-21(2)33-26-9-4-3-8-25(26)30-16-7-15-29(17-18-30)14-5-6-19-32-23-12-10-22-11-13-27(31)28-24(22)20-23/h3-4,8-13,20-21H,5-7,14-19H2,1-2H3,(H,28,31) OKJIXAFKUUQQCX-UHFFFAOYSA-N 185688 UNC10107969::US9156822, 18 D(2) dopamine receptor Homo sapiens 4.2 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185688&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76372506 315516379 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334979 Clc1cccc(N2CCCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O2/c22-16-4-1-5-19(20(16)23)27-10-2-8-26(11-12-27)9-3-13-29-15-6-7-17-18(14-15)25-21(28)24-17/h1,4-7,14H,2-3,8-13H2,(H2,24,25,28) ARPHSPFYEOAIMK-UHFFFAOYSA-N 185689 UNC10108005::US9156822, 19 D(2) dopamine receptor Homo sapiens 8.5 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185689&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225823 315516380 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334980 Clc1cccc(N2CCN(CCCOc3ccc4cn[nH]c4c3)CC2)c1Cl InChI=1S/C20H22Cl2N4O/c21-17-3-1-4-19(20(17)22)26-10-8-25(9-11-26)7-2-12-27-16-6-5-15-14-23-24-18(15)13-16/h1,3-6,13-14H,2,7-12H2,(H,23,24) WOXYKTMEOIXZAQ-UHFFFAOYSA-N 50395572 CHEMBL2165116::UNC10099976::US9156822, 20 D(2) dopamine receptor Homo sapiens 59 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597939 163344596 CHEMBL2165116 ZINC95553616 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334981 Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C22H24Cl2N2OS/c23-19-5-3-4-18(22(19)24)16-8-11-26(12-9-16)10-1-2-13-27-17-6-7-21-20(14-17)25-15-28-21/h3-7,14-16H,1-2,8-13H2 DXXXGJIMFKZHRL-UHFFFAOYSA-N 50395578 CHEMBL2165137::UNC10099993::US9156822, 21 D(2) dopamine receptor Homo sapiens 82 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597090 163344602 CHEMBL2165137 ZINC95557182 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334982 Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C21H22Cl2N2OS/c22-18-4-1-3-17(21(18)23)15-7-10-25(11-8-15)9-2-12-26-16-5-6-20-19(13-16)24-14-27-20/h1,3-6,13-15H,2,7-12H2 URYZTMIOHYGTNJ-UHFFFAOYSA-N 50395577 CHEMBL2165138::UNC10099994::US9156822, 22 D(2) dopamine receptor Homo sapiens 100 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599142 163344601 CHEMBL2165138 ZINC72318113 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334983 Clc1cccc(N2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C20H21Cl2N3OS/c21-16-3-1-4-18(20(16)22)25-10-8-24(9-11-25)7-2-12-26-15-5-6-19-17(13-15)23-14-27-19/h1,3-6,13-14H,2,7-12H2 VBHBKXBUHHJVBZ-UHFFFAOYSA-N 50395576 CHEMBL2165139::UNC10099995::US9156822, 23 D(2) dopamine receptor Homo sapiens 107 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599143 163344600 CHEMBL2165139 ZINC95553637 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334984 Clc1cccc(C2CCN(CCCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C22H25Cl2N3O2/c23-18-5-3-4-17(21(18)24)15-8-11-27(12-9-15)10-1-2-13-29-16-6-7-19-20(14-16)26-22(28)25-19/h3-7,14-15H,1-2,8-13H2,(H2,25,26,28) JEZQFKLGYQTDDK-UHFFFAOYSA-N 50395573 CHEMBL2165115::UNC10108006::US9156822, 24 D(2) dopamine receptor Homo sapiens 25 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599144 163344597 CHEMBL2165115 ZINC95553126 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334985 Clc1cccc(N2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-20-4-3-5-21(22(20)25)28-13-11-27(12-14-28)10-1-2-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h3-7,16H,1-2,8-15H2,(H,26,29) VBFRZHYHMOZIEU-UHFFFAOYSA-N 50395582 CHEMBL2165133::UNC10000004::US9156822, 25 D(2) dopamine receptor Homo sapiens 18 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599145 163344606 CHEMBL2165133 ZINC95552743 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334986 Clc1cccc(N2CCN(CC3CCC(COc4ccc5CCC(=O)Nc5c4)CC3)CC2)c1Cl InChI=1S/C27H33Cl2N3O2/c28-23-2-1-3-25(27(23)29)32-14-12-31(13-15-32)17-19-4-6-20(7-5-19)18-34-22-10-8-21-9-11-26(33)30-24(21)16-22/h1-3,8,10,16,19-20H,4-7,9,11-15,17-18H2,(H,30,33) CRARFJICFRVCGK-UHFFFAOYSA-N 185690 UNC10000007::US9156822, 26 D(2) dopamine receptor Homo sapiens 2100 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185690&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599146 315516381 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334987 Clc1cccc(N2CCN(CC#CCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H23Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,7,9-15H2,(H,26,29) FNZOOYYZKQCPEG-UHFFFAOYSA-N 50395585 CHEMBL2165129::UNC10000009::US9156822, 27 D(2) dopamine receptor Homo sapiens 610 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395585&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599147 163344609 CHEMBL2165129 ZINC95554397 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334988 Clc1cccc(N2CCN(CCCCOc3ccc4cn[nH]c4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-18-4-3-5-20(21(18)23)27-11-9-26(10-12-27)8-1-2-13-28-17-7-6-16-15-24-25-19(16)14-17/h3-7,14-15H,1-2,8-13H2,(H,24,25) IKOXHMZXTCWMQE-UHFFFAOYSA-N 50395581 CHEMBL2165134::UNC10000010::US9156822, 28 D(2) dopamine receptor Homo sapiens 92 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597091 163344605 CHEMBL2165134 ZINC95552916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334989 Clc1cccc(N2CCN(C\C=C\COc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H25Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1-6,8,16H,7,9-15H2,(H,26,29)/b2-1+ SKGKYEPRBPJYRW-OWOJBTEDSA-N 185691 UNC10000011::US9156822, 29 D(2) dopamine receptor Homo sapiens 26 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185691&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66633745 315516382 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334990 Clc1cccc(N2CCN(Cc3cccc(Oc4ccc5CCC(=O)Nc5c4)c3)CC2)c1Cl InChI=1S/C26H25Cl2N3O2/c27-22-5-2-6-24(26(22)28)31-13-11-30(12-14-31)17-18-3-1-4-20(15-18)33-21-9-7-19-8-10-25(32)29-23(19)16-21/h1-7,9,15-16H,8,10-14,17H2,(H,29,32) PULGLQOWTRCVQB-UHFFFAOYSA-N 50395584 CHEMBL2165131::UNC10099972::US9156822, 30 D(2) dopamine receptor Homo sapiens 58 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395584&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559506 163344608 CHEMBL2165131 ZINC95552101 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334991 Clc1cccc(N2CCN(Cc3ccc(Oc4ccc5CCC(=O)Nc5c4)cc3)CC2)c1Cl InChI=1S/C26H25Cl2N3O2/c27-22-2-1-3-24(26(22)28)31-14-12-30(13-15-31)17-18-4-8-20(9-5-18)33-21-10-6-19-7-11-25(32)29-23(19)16-21/h1-6,8-10,16H,7,11-15,17H2,(H,29,32) MCIWPVPYVLZFFO-UHFFFAOYSA-N 50395583 CHEMBL2165132::UNC10099973::US9156822, 31 D(2) dopamine receptor Homo sapiens 399 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559507 163344607 CHEMBL2165132 ZINC95556448 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334992 Clc1cccc(N2CCN(CCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C22H25Cl2N3O2/c23-19-3-1-4-20(21(19)24)27-12-10-26(11-13-27)9-2-14-29-17-6-5-16-7-8-25-22(28)18(16)15-17/h1,3-6,15H,2,7-14H2,(H,25,28) QXPBZNWEPREKHB-UHFFFAOYSA-N 50395571 CHEMBL2165117::UNC10099981::US10501452, Compound A::US9156822, 32 D(2) dopamine receptor Homo sapiens 30 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597092 163344595 CHEMBL2165117 ZINC95555707 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334993 Clc1cccc(C2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl InChI=1S/C24H28Cl2N2O2/c25-22-5-3-4-20(23(22)26)18-9-13-28(14-10-18)12-1-2-15-30-19-7-6-17-8-11-27-24(29)21(17)16-19/h3-7,16,18H,1-2,8-15H2,(H,27,29) HVXBMABYUWVXDA-UHFFFAOYSA-N 185692 UNC10099985::US9156822, 33 D(2) dopamine receptor Homo sapiens 64 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597093 315516383 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334994 Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C20H22Cl2N4O2/c21-15-3-1-4-18(19(15)22)26-10-8-25(9-11-26)7-2-12-28-14-5-6-16-17(13-14)24-20(27)23-16/h1,3-6,13H,2,7-12H2,(H2,23,24,27) NKDQNOFCLUVBIY-UHFFFAOYSA-N 185693 UNC10099988::US9156822, 34 D(2) dopamine receptor Homo sapiens 25 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121225824 315516384 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334995 Clc1cccc(N2CCN(CCCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O2/c22-16-4-3-5-19(20(16)23)27-11-9-26(10-12-27)8-1-2-13-29-15-6-7-17-18(14-15)25-21(28)24-17/h3-7,14H,1-2,8-13H2,(H2,24,25,28) LROJLXGQKUBROL-UHFFFAOYSA-N 50395580 CHEMBL2165135::UNC10099990::US9156822, 35 D(2) dopamine receptor Homo sapiens 65 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597095 163344604 CHEMBL2165135 ZINC95556802 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334996 Clc1cccc(N2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C21H23Cl2N3OS/c22-17-4-3-5-19(21(17)23)26-11-9-25(10-12-26)8-1-2-13-27-16-6-7-20-18(14-16)24-15-28-20/h3-7,14-15H,1-2,8-13H2 JBKITGSPOFFGJB-UHFFFAOYSA-N 50395579 CHEMBL2165136::UNC10099991::US9156822, 36 D(2) dopamine receptor Homo sapiens 64 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597225 163344603 CHEMBL2165136 ZINC95553695 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334997 COc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1 InChI=1S/C23H30N4O3/c1-29-20-7-3-2-6-19(20)27-15-13-26(14-16-27)12-4-5-17-30-22-11-9-18-8-10-21(28)24-23(18)25-22/h2-3,6-7,9,11H,4-5,8,10,12-17H2,1H3,(H,24,25,28) DTVAIMZRGJKGPN-UHFFFAOYSA-N 185694 UNC10107957::US9156822, 37 D(2) dopamine receptor Homo sapiens 17 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185694&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597226 315516385 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334998 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4NC(=O)COc34)cc2N1 InChI=1S/C25H30N4O4/c30-23-9-7-18-6-8-19(16-21(18)27-23)32-15-2-1-10-28-11-13-29(14-12-28)22-5-3-4-20-25(22)33-17-24(31)26-20/h3-6,8,16H,1-2,7,9-15,17H2,(H,26,31)(H,27,30) IPAFOBZCTHBJBT-UHFFFAOYSA-N 185695 UNC10108010::US9156822, 38 D(2) dopamine receptor Homo sapiens 0.4 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185695&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597940 315516386 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 334999 COc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 InChI=1S/C24H31N3O3/c1-29-23-7-3-2-6-22(23)27-15-13-26(14-16-27)12-4-5-17-30-20-10-8-19-9-11-24(28)25-21(19)18-20/h2-3,6-8,10,18H,4-5,9,11-17H2,1H3,(H,25,28) HVSUPPZVIPTMEM-UHFFFAOYSA-N 50349866 CHEMBL160296::CHEMBL1813590::UNC10108016::US9156822, 39 D(2) dopamine receptor Homo sapiens 0.5 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50349866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50349866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692886 136356552 CHEMBL160296CHEMBL1813590 ZINC27725864 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335000 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)cc2N1 InChI=1S/C25H31N3O4/c29-24-9-7-19-6-8-20(18-21(19)26-24)30-15-2-1-10-27-11-13-28(14-12-27)22-4-3-5-23-25(22)32-17-16-31-23/h3-6,8,18H,1-2,7,9-17H2,(H,26,29) AMAZFBCTWBJQKF-UHFFFAOYSA-N 185696 UNC10108017::US9156822, 40 D(2) dopamine receptor Homo sapiens 1.5 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185696&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597227 315516387 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335001 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)nc2N1 InChI=1S/C24H30N4O4/c29-21-8-6-18-7-9-22(26-24(18)25-21)31-15-2-1-10-27-11-13-28(14-12-27)19-4-3-5-20-23(19)32-17-16-30-20/h3-5,7,9H,1-2,6,8,10-17H2,(H,25,26,29) NENVXZKTDUNSBM-UHFFFAOYSA-N 185697 UNC10108018::US9156822, 41 D(2) dopamine receptor Homo sapiens 0.6 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21073553 315516388 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335002 O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)cc2[nH]1 InChI=1S/C25H29N3O4/c29-24-9-7-19-6-8-20(18-21(19)26-24)30-15-2-1-10-27-11-13-28(14-12-27)22-4-3-5-23-25(22)32-17-16-31-23/h3-9,18H,1-2,10-17H2,(H,26,29) WKXGCJMHUWZCIC-UHFFFAOYSA-N 185698 UNC10108019::US9156822, 42 D(2) dopamine receptor Homo sapiens 0.9 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77156277 315516389 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335003 CC(=O)Nc1cc(OCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc1C InChI=1S/C23H29Cl2N3O2/c1-17-8-9-19(16-21(17)26-18(2)29)30-15-4-3-10-27-11-13-28(14-12-27)22-7-5-6-20(24)23(22)25/h5-9,16H,3-4,10-15H2,1-2H3,(H,26,29) PYODBBFAXCRGHN-UHFFFAOYSA-N 185699 UNC10108049::US9156822, 43 D(2) dopamine receptor Homo sapiens 9.2 7.4 US Patent 10.7270/Q2H41Q6D aid1801736 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185699&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597942 315516390 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335004 Clc1cccc(N2CCCN(CCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-1-5-21(23(19)25)28-12-2-10-27(13-14-28)11-3-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h1,4-6,8,16H,2-3,7,9-15H2,(H,26,29) CWVVNHIKQCMQOH-UHFFFAOYSA-N 185677 UNC10000003::US9156822, 1 D(2) dopamine receptor Homo sapiens 6 US Patent 10.7270/Q2H41Q6D aid1801737 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=185677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=185677&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597937 315516368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335005 Clc1cccc(N2CCCN(CCCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1Cl InChI=1S/C24H27Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-10,17H,1-2,4,11-16H2,(H,27,30) HWTAZRRAKMJTGD-UHFFFAOYSA-N 50395568 CHEMBL2165120::UNC10099978::US9156822, 4 D(2) dopamine receptor Homo sapiens 1 US Patent 10.7270/Q2H41Q6D aid1801737 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66559588 163344592 CHEMBL2165120 ZINC95552147 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335006 Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl InChI=1S/C21H22Cl2N2OS/c22-18-4-1-3-17(21(18)23)15-7-10-25(11-8-15)9-2-12-26-16-5-6-20-19(13-16)24-14-27-20/h1,3-6,13-15H,2,7-12H2 URYZTMIOHYGTNJ-UHFFFAOYSA-N 50395577 CHEMBL2165138::UNC10099994::US9156822, 22 D(2) dopamine receptor Homo sapiens 50 US Patent 10.7270/Q2H41Q6D aid1801737 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56599142 163344601 CHEMBL2165138 ZINC72318113 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335007 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 8 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335017 Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4n3)CC2)c1Cl InChI=1S/C23H28Cl2N4O2/c24-18-5-3-6-19(22(18)25)29-13-4-12-28(14-15-29)11-1-2-16-31-21-10-8-17-7-9-20(30)26-23(17)27-21/h3,5-6,8,10H,1-2,4,7,9,11-16H2,(H,26,27,30) JQSRFMXTGAVHIR-UHFFFAOYSA-N 50395569 CHEMBL2165119::UNC10099975::US9156822, 3 or UNC9975 D(2) dopamine receptor Homo sapiens 2.6 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56593482 163344593 CHEMBL2165119 ZINC72318111 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 335027 Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30) NGCKUAWDNUFNBB-UHFFFAOYSA-N 50395587 CHEMBL2165126::UNC10000006::US9156822, 2 D(2) dopamine receptor Homo sapiens 5 7.4 US Patent 10.7270/Q2H41Q6D aid1801734 US9156822 Jin, J; Roth, B; Frye, S University of North Carolina at Chapel Hill http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56597938 163344611 CHEMBL2165126 ZINC72318112 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354195 COc1cc2CCN3CCc4cc(OC)c(OC)cc4CC3c2cc1OC InChI=1S/C22H27NO4/c1-24-19-10-14-5-7-23-8-6-15-11-20(25-2)22(27-4)13-17(15)18(23)9-16(14)12-21(19)26-3/h10-13,18H,5-9H2,1-4H3 FDWCQJQXTYABFS-UHFFFAOYSA-N 199154 2,3,11,12-tetramethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline (15a) D(2) dopamine receptor Homo sapiens 26.53 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199154&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 390003 318490114 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354196 COc1cc2CCN3CCc4cc(OC)c(OC)cc4CC3c2cc1O InChI=1S/C21H25NO4/c1-24-19-10-14-5-7-22-6-4-13-9-20(25-2)21(26-3)11-15(13)8-17(22)16(14)12-18(19)23/h9-12,17,23H,4-8H2,1-3H3 ITLWJNRXZRYABC-UHFFFAOYSA-N 199155 3,11,12-trimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinolin-2-ol (15b) D(2) dopamine receptor Homo sapiens 6.96 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199155&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198682 318490115 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354197 COc1cc2CCN3CCc4c(CC3c2cc1OC)ccc(OC)c4OC InChI=1S/C22H27NO4/c1-24-19-6-5-14-11-18-17-13-21(26-3)20(25-2)12-15(17)7-9-23(18)10-8-16(14)22(19)27-4/h5-6,12-13,18H,7-11H2,1-4H3 FLVNRLZZKCMBOV-UHFFFAOYSA-N 199156 2,3,10,11-tetramethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline (15c) D(2) dopamine receptor Homo sapiens 29.82 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199156&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198683 318490116 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354198 COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4OC InChI=1S/C21H25NO4/c1-24-19-5-4-13-10-17-16-12-18(23)20(25-2)11-14(16)6-8-22(17)9-7-15(13)21(19)26-3/h4-5,11-12,17,23H,6-10H2,1-3H3 MULALUUHQOTCGR-UHFFFAOYSA-N 199157 3,10,11-trimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinolin-2-ol (15d) D(2) dopamine receptor Homo sapiens 83.95 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199157&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198684 318490117 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354199 COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4O InChI=1S/C20H23NO4/c1-24-18-4-3-12-9-16-15-11-17(22)19(25-2)10-13(15)5-7-21(16)8-6-14(12)20(18)23/h3-4,10-11,16,22-23H,5-9H2,1-2H3 XKXRGRIEYGPFJV-UHFFFAOYSA-N 199158 3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol ((+)-15e)::3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol ((-)-15e)::3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol (15e) D(2) dopamine receptor Homo sapiens 36.59 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198685 318490118 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354200 COc1ccc2CC3N(CCc4cc5OCOc5cc34)CCc2c1OC InChI=1S/C21H23NO4/c1-23-18-4-3-13-9-17-16-11-20-19(25-12-26-20)10-14(16)5-7-22(17)8-6-15(13)21(18)24-2/h3-4,10-11,17H,5-9,12H2,1-2H3 PSFUKFPBOCFKKC-UHFFFAOYSA-N 199159 Hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline, 16 D(2) dopamine receptor Homo sapiens 4.26 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198686 318490119 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354201 COc1ccc2CC3N(CCc4cc(O)c(O)cc34)CCc2c1OC InChI=1S/C20H23NO4/c1-24-19-4-3-12-9-16-15-11-18(23)17(22)10-13(15)5-7-21(16)8-6-14(12)20(19)25-2/h3-4,10-11,16,22-23H,5-9H2,1-2H3 KYXWUHSGTSJOOO-UHFFFAOYSA-N 199160 Hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline, 17 D(2) dopamine receptor Homo sapiens 39.24 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199160&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198687 318490120 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354202 Oc1cc2CCN3CCc4c(CC3c2cc1O)ccc(O)c4O InChI=1S/C18H19NO4/c20-15-2-1-10-7-14-13-9-17(22)16(21)8-11(13)3-5-19(14)6-4-12(10)18(15)23/h1-2,8-9,14,20-23H,3-7H2 CTNWBZPXZUTRQV-UHFFFAOYSA-N 199161 5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,3,10,11-tetraol (18) D(2) dopamine receptor Homo sapiens 72.15 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199161&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198688 318490121 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354203 COc1cc2CCN3CCc4c(CC3c2cc1OC(C)=O)ccc(OC)c4OC InChI=1S/C23H27NO5/c1-14(25)29-22-13-18-16(12-21(22)27-3)7-9-24-10-8-17-15(11-19(18)24)5-6-20(26-2)23(17)28-4/h5-6,12-13,19H,7-11H2,1-4H3 GMILYSPIEHVQHZ-UHFFFAOYSA-N 199162 3,10,11-trimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinolin-2-ylacetate (19) D(2) dopamine receptor Homo sapiens 51.97 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199162&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198689 318490122 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354204 COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4O InChI=1S/C20H23NO4/c1-24-18-4-3-12-9-16-15-11-17(22)19(25-2)10-13(15)5-7-21(16)8-6-14(12)20(18)23/h3-4,10-11,16,22-23H,5-9H2,1-2H3 XKXRGRIEYGPFJV-UHFFFAOYSA-N 199158 3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol ((+)-15e)::3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol ((-)-15e)::3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol (15e) D(2) dopamine receptor Homo sapiens 34.40 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198685 318490118 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354205 COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4O InChI=1S/C20H23NO4/c1-24-18-4-3-12-9-16-15-11-17(22)19(25-2)10-13(15)5-7-21(16)8-6-14(12)20(18)23/h3-4,10-11,16,22-23H,5-9H2,1-2H3 XKXRGRIEYGPFJV-UHFFFAOYSA-N 199158 3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol ((+)-15e)::3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol ((-)-15e)::3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol (15e) D(2) dopamine receptor Homo sapiens 58.26 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122198685 318490118 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 354206 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 1.08 Curated from the literature by BindingDB 10.1111/cbdd.12796 10.7270/Q2QF8RQ5 27232055 aid1802075 Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Fudan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 389891 COc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(OCCCCN3CCN(CC3)c3ccccc3OC)cc2O1 InChI=1S/C31H36N2O6/c1-36-23-11-9-22(10-12-23)29-21-27(35)31-26(34)19-24(20-30(31)39-29)38-18-6-5-13-32-14-16-33(17-15-32)25-7-3-4-8-28(25)37-2/h3-4,7-12,19-20,29,34H,5-6,13-18,21H2,1-2H3/t29-/m0/s1 CSJWCVLNTAZHKD-LJAQVGFWSA-N 223064 5-Hydroxy-2-(4-methoxyphenyl)-7-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)chroman-4-one (7a) D(2) dopamine receptor Homo sapiens 205 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12843 10.7270/Q2JW8CR0 27543496 aid1802636 Gu, HS; Chen, X; Zhang, JW; Zhang, L; Li, L Key Laboratory for Neurodegenerative Diseases of Ministry of Education http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223064&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126961571 336284941 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 389892 COc1ccccc1N1CCN(CCCCOc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(C)cc2)CC1 InChI=1S/C31H36N2O5/c1-22-9-11-23(12-10-22)29-21-27(35)31-26(34)19-24(20-30(31)38-29)37-18-6-5-13-32-14-16-33(17-15-32)25-7-3-4-8-28(25)36-2/h3-4,7-12,19-20,29,34H,5-6,13-18,21H2,1-2H3/t29-/m0/s1 QQIXFSRRLUIGLM-LJAQVGFWSA-N 223065 5-Hydroxy-2-(4-methylphenyl)-7-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)chroman-4-one (7b) D(2) dopamine receptor Homo sapiens 346 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12843 10.7270/Q2JW8CR0 27543496 aid1802636 Gu, HS; Chen, X; Zhang, JW; Zhang, L; Li, L Key Laboratory for Neurodegenerative Diseases of Ministry of Education http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126961572 336284942 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 389893 COc1ccccc1N1CCN(CCCCOc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(F)cc2)CC1 InChI=1S/C30H33FN2O5/c1-36-27-7-3-2-6-24(27)33-15-13-32(14-16-33)12-4-5-17-37-23-18-25(34)30-26(35)20-28(38-29(30)19-23)21-8-10-22(31)11-9-21/h2-3,6-11,18-19,28,34H,4-5,12-17,20H2,1H3/t28-/m0/s1 HTAKTCONXBKFJI-NDEPHWFRSA-N 223066 5-Hydroxy-2-(fluorophenyl)-7-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)chroman-4-one (7c) D(2) dopamine receptor Homo sapiens 57.3 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12843 10.7270/Q2JW8CR0 27543496 aid1802636 Gu, HS; Chen, X; Zhang, JW; Zhang, L; Li, L Key Laboratory for Neurodegenerative Diseases of Ministry of Education http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223066&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126961573 336284943 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 389894 COc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(OCCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2O1 InChI=1S/C32H33FN2O6/c1-38-23-7-4-20(5-8-23)28-19-27(37)31-26(36)17-24(18-30(31)40-28)39-15-3-2-12-35-13-10-21(11-14-35)32-25-9-6-22(33)16-29(25)41-34-32/h4-9,16-18,21,28,36H,2-3,10-15,19H2,1H3/t28-/m0/s1 MPKCUAWIBWMDIB-NDEPHWFRSA-N 223067 5-Hydroxy-2-(4-methoxyphenyl)-7-(4-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)butoxy)chroman-4-one (7d) D(2) dopamine receptor Homo sapiens 51.3 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12843 10.7270/Q2JW8CR0 27543496 aid1802636 Gu, HS; Chen, X; Zhang, JW; Zhang, L; Li, L Key Laboratory for Neurodegenerative Diseases of Ministry of Education http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126961574 336284944 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 389895 Oc1cc(OCCCCN2CCC(CC2)c2noc3cc(F)ccc23)cc2O[C@@H](CC(=O)c12)c1ccc(F)cc1 InChI=1S/C31H30F2N2O5/c32-21-5-3-19(4-6-21)27-18-26(37)30-25(36)16-23(17-29(30)39-27)38-14-2-1-11-35-12-9-20(10-13-35)31-24-8-7-22(33)15-28(24)40-34-31/h3-8,15-17,20,27,36H,1-2,9-14,18H2/t27-/m0/s1 KUOYFTRGKVRORO-MHZLTWQESA-N 223068 5-Hydroxy-2-(4-fluorophenyl)-7-(4-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)butoxy)chroman-4-one (7e) D(2) dopamine receptor Homo sapiens 87.7 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12843 10.7270/Q2JW8CR0 27543496 aid1802636 Gu, HS; Chen, X; Zhang, JW; Zhang, L; Li, L Key Laboratory for Neurodegenerative Diseases of Ministry of Education http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223068&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126961575 336284945 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 389896 COc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(OCCCN3CCN(CC3)c3ccccc3OC)cc2O1 InChI=1S/C30H34N2O6/c1-35-22-10-8-21(9-11-22)28-20-26(34)30-25(33)18-23(19-29(30)38-28)37-17-5-12-31-13-15-32(16-14-31)24-6-3-4-7-27(24)36-2/h3-4,6-11,18-19,28,33H,5,12-17,20H2,1-2H3/t28-/m0/s1 JKWDTKHKBBCJDS-NDEPHWFRSA-N 223069 5-Hydroxy-2-(4-methoxyphenyl)-7-(4-(4-(2-methoxyphenyl)piperazin-1-yl)propoxy)chroman-4-one (7f) D(2) dopamine receptor Homo sapiens 220 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12843 10.7270/Q2JW8CR0 27543496 aid1802636 Gu, HS; Chen, X; Zhang, JW; Zhang, L; Li, L Key Laboratory for Neurodegenerative Diseases of Ministry of Education http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223069&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126961576 336284946 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 389897 COc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2O1 InChI=1S/C31H31FN2O6/c1-37-22-6-3-19(4-7-22)27-18-26(36)30-25(35)16-23(17-29(30)39-27)38-14-2-11-34-12-9-20(10-13-34)31-24-8-5-21(32)15-28(24)40-33-31/h3-8,15-17,20,27,35H,2,9-14,18H2,1H3/t27-/m0/s1 JRQAGUNVYLGWCD-MHZLTWQESA-N 223070 5-Hydroxy-2-(4-methoxyphenyl)-7-(4-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propoxy)chroman-4-one (7g) D(2) dopamine receptor Homo sapiens 116 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12843 10.7270/Q2JW8CR0 27543496 aid1802636 Gu, HS; Chen, X; Zhang, JW; Zhang, L; Li, L Key Laboratory for Neurodegenerative Diseases of Ministry of Education http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223070&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126961577 336284947 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410729 COc1ccc(OC)c2CN3CCc4cc(OC)c(OC)cc4[C@@H]3Cc12 InChI=1S/C21H25NO4/c1-23-18-5-6-19(24-2)16-12-22-8-7-13-9-20(25-3)21(26-4)11-14(13)17(22)10-15(16)18/h5-6,9,11,17H,7-8,10,12H2,1-4H3/t17-/m0/s1 MLYZNZVURPVMPQ-KRWDZBQOSA-N 235773 US9359372, DC037008 D(2) dopamine receptor Homo sapiens 334.38 1727.6 30.00 C US Patent 10.7270/Q2736PSP aid1803050 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71109989 340129366 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410730 C1Oc2cc3C[C@@H]4N(CCc5cc6OCOc6cc45)Cc3cc2O1 InChI=1S/C19H17NO4/c1-2-20-8-13-6-18-17(22-9-23-18)5-12(13)3-15(20)14-7-19-16(4-11(1)14)21-10-24-19/h4-7,15H,1-3,8-10H2/t15-/m0/s1 DEXCWVBNPJKCOQ-HNNXBMFYSA-N 235775 US9359372, DC037012 D(2) dopamine receptor Homo sapiens 239.9 1239.4 30.00 C US Patent 10.7270/Q2736PSP aid1803050 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21589014 340129368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410731 COc1ccc(OC)c2CN3CCc4cc5OCOc5cc4[C@@H]3Cc12 InChI=1S/C20H21NO4/c1-22-17-3-4-18(23-2)15-10-21-6-5-12-7-19-20(25-11-24-19)9-13(12)16(21)8-14(15)17/h3-4,7,9,16H,5-6,8,10-11H2,1-2H3/t16-/m0/s1 OIKSHMCSVZMXCU-INIZCTEOSA-N 235777 US9359372, DC037013::US9359372, DC037034 D(2) dopamine receptor Homo sapiens 485.43 2508.05 30.00 C US Patent 10.7270/Q2736PSP aid1803050 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71110293 340129370 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410732 COc1cc2CCN3Cc4c(C)cc(C)cc4C[C@H]3c2cc1OC InChI=1S/C21H25NO2/c1-13-7-14(2)18-12-22-6-5-15-10-20(23-3)21(24-4)11-17(15)19(22)9-16(18)8-13/h7-8,10-11,19H,5-6,9,12H2,1-4H3/t19-/m0/s1 BEZZGCHAIFWOPE-IBGZPJMESA-N 50387560 CHEMBL2057451::US9359372, DC037017 D(2) dopamine receptor Homo sapiens 223.61 1155.3 30.00 C US Patent 10.7270/Q2736PSP aid1803050 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70682090 160866643 CHEMBL2057451 ZINC84690166 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410733 COc1cc2CCN3Cc4cc5OCOc5cc4C[C@H]3c2cc1O InChI=1S/C19H19NO4/c1-22-17-5-11-2-3-20-9-13-7-19-18(23-10-24-19)6-12(13)4-15(20)14(11)8-16(17)21/h5-8,15,21H,2-4,9-10H2,1H3/t15-/m0/s1 CIEGYDLRUMZWQS-HNNXBMFYSA-N 50429044 CHEMBL2334893::US9359372, DC037029 D(2) dopamine receptor Homo sapiens 32.16 91.11 30.00 C US Patent 10.7270/Q2736PSP aid1803050 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50429044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50429044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71109897 164157919 CHEMBL2334893 ZINC13408680 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410734 COc1cc2CCN3Cc4c(C)cc(C)cc4C[C@H]3c2cc1O InChI=1S/C20H23NO2/c1-12-6-13(2)17-11-21-5-4-14-9-20(23-3)19(22)10-16(14)18(21)8-15(17)7-12/h6-7,9-10,18,22H,4-5,8,11H2,1-3H3/t18-/m0/s1 OGNNKKYFJYJQEU-SFHVURJKSA-N 50387557 CHEMBL2057457::US9359372, DC037031 D(2) dopamine receptor Homo sapiens 160.99 456.13 30.00 C US Patent 10.7270/Q2736PSP aid1803050 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70692656 160866640 CHEMBL2057457 ZINC84709629 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410735 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.5 2.56 30.00 C US Patent 10.7270/Q2736PSP aid1803050 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410736 COc1ccc(OC)c2CN3CCc4cc(OC)c(OC)cc4C3Cc12 InChI=1S/C21H25NO4/c1-23-18-5-6-19(24-2)16-12-22-8-7-13-9-20(25-3)21(26-4)11-14(13)17(22)10-15(16)18/h5-6,9,11,17H,7-8,10,12H2,1-4H3 MLYZNZVURPVMPQ-UHFFFAOYSA-N 235768 US9359372, DC037003 D(2) dopamine receptor Homo sapiens 3300 37.00 C US Patent 10.7270/Q2736PSP aid1803053 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71110290 340129361 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410737 COc1ccc(OC)c2CN3CCc4cc(OC)c(OC)cc4[C@@H]3Cc12 InChI=1S/C21H25NO4/c1-23-18-5-6-19(24-2)16-12-22-8-7-13-9-20(25-3)21(26-4)11-14(13)17(22)10-15(16)18/h5-6,9,11,17H,7-8,10,12H2,1-4H3/t17-/m0/s1 MLYZNZVURPVMPQ-KRWDZBQOSA-N 235773 US9359372, DC037008 D(2) dopamine receptor Homo sapiens 4030 37.00 C US Patent 10.7270/Q2736PSP aid1803053 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71109989 340129366 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410738 COc1ccc(OC)c2CN3CCc4cc5OCOc5cc4[C@@H]3Cc12 InChI=1S/C20H21NO4/c1-22-17-3-4-18(23-2)15-10-21-6-5-12-7-19-20(25-11-24-19)9-13(12)16(21)8-14(15)17/h3-4,7,9,16H,5-6,8,10-11H2,1-2H3/t16-/m0/s1 OIKSHMCSVZMXCU-INIZCTEOSA-N 235777 US9359372, DC037013::US9359372, DC037034 D(2) dopamine receptor Homo sapiens 9740 37.00 C US Patent 10.7270/Q2736PSP aid1803053 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71110293 340129370 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410739 COc1cc2CCN3Cc4c(C)cc(C)cc4C[C@H]3c2cc1OC InChI=1S/C21H25NO2/c1-13-7-14(2)18-12-22-6-5-15-10-20(23-3)21(24-4)11-17(15)19(22)9-16(18)8-13/h7-8,10-11,19H,5-6,9,12H2,1-4H3/t19-/m0/s1 BEZZGCHAIFWOPE-IBGZPJMESA-N 50387560 CHEMBL2057451::US9359372, DC037017 D(2) dopamine receptor Homo sapiens 16190 37.00 C US Patent 10.7270/Q2736PSP aid1803053 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70682090 160866643 CHEMBL2057451 ZINC84690166 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410740 COc1cc2CCN3Cc4c(C)cc(C)cc4CC3c2cc1OC InChI=1S/C21H25NO2/c1-13-7-14(2)18-12-22-6-5-15-10-20(23-3)21(24-4)11-17(15)19(22)9-16(18)8-13/h7-8,10-11,19H,5-6,9,12H2,1-4H3 BEZZGCHAIFWOPE-UHFFFAOYSA-N 60961 US9359372, DC037018 D(2) dopamine receptor Homo sapiens 15610 37.00 C US Patent 10.7270/Q2736PSP aid1803053 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70684207 340129240 ZINC16196025 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410741 COc1cc2CC3N(CCc4cc(O)c(O)cc34)Cc2cc1OC InChI=1S/C19H21NO4/c1-23-18-7-12-5-15-14-9-17(22)16(21)6-11(14)3-4-20(15)10-13(12)8-19(18)24-2/h6-9,15,21-22H,3-5,10H2,1-2H3 BTUIZHMEGKWEMO-UHFFFAOYSA-N 235774 US9359372, DC037024 D(2) dopamine receptor Homo sapiens 591 37.00 C US Patent 10.7270/Q2736PSP aid1803053 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71474024 340129367 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410742 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 1.4 37.00 C US Patent 10.7270/Q2736PSP aid1803053 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410743 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 462 37.00 C US Patent 10.7270/Q2736PSP aid1803053 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410758 COc1c(O)ccc2C[C@@H]3N(CCc4cc5CCOc5cc34)Cc12 InChI=1S/C20H21NO3/c1-23-20-16-11-21-6-4-13-8-14-5-7-24-19(14)10-15(13)17(21)9-12(16)2-3-18(20)22/h2-3,8,10,17,22H,4-7,9,11H2,1H3/t17-/m0/s1 HYIGJQLIWSXNQW-KRWDZBQOSA-N 50429046 CHEMBL2334882::US9359372, DC037081 D(2) dopamine receptor Homo sapiens 146.9 7.4 30.00 C US Patent 10.7270/Q2736PSP aid1803051 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50429046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50429046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71109804 164157921 CHEMBL2334882 ZINC95591191 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 410759 COc1cc2CCN3Cc4c(C)cc(C)cc4C[C@H]3c2cc1O InChI=1S/C20H23NO2/c1-12-6-13(2)17-11-21-5-4-14-9-20(23-3)19(22)10-16(14)18(21)8-15(17)7-12/h6-7,9-10,18,22H,4-5,8,11H2,1-3H3/t18-/m0/s1 OGNNKKYFJYJQEU-SFHVURJKSA-N 50387557 CHEMBL2057457::US9359372, DC037031 D(2) dopamine receptor Homo sapiens 160.9 7.4 30.00 C US Patent 10.7270/Q2736PSP aid1803051 US9359372 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Shanghai Institute of Materia Medica, Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70692656 160866640 CHEMBL2057457 ZINC84709629 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432921 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 2.92 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432922 Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2cccc3OCCOc23)c1 InChI=1S/C24H24FN3O2/c25-21-6-4-19(5-7-21)20-14-18(15-26-16-20)17-27-8-10-28(11-9-27)22-2-1-3-23-24(22)30-13-12-29-23/h1-7,14-16H,8-13,17H2 IUVSEUFHPNITEQ-UHFFFAOYSA-N 248056 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]piperazine::Adoprazine D(2) dopamine receptor Homo sapiens 8.40 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248056&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9887537 346542586 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432923 O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4ccccc4)CC3)c2o1 InChI=1S/C24H23N3O2/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19/h1-11,16H,12-15,17H2,(H,25,28) CYGODHVAJQTCBG-UHFFFAOYSA-N 50241119 7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzooxazol-2-one::BIFEPRUNOX::CHEMBL218166 D(2) dopamine receptor Homo sapiens 8.81 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 208951 104098615 CHEMBL218166 DB04888 ZINC52971454 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432924 O=c1[nH]c2ccc(cc2[nH]1)C1CCN(Cc2ccc(cc2)-c2ccccc2)CC1 InChI=1S/C25H25N3O/c29-25-26-23-11-10-22(16-24(23)27-25)21-12-14-28(15-13-21)17-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-11,16,21H,12-15,17H2,(H2,26,27,29) QKBGISPYLKVTQT-UHFFFAOYSA-N 248044 5-(1-(biphenyl-4-ylmethyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one (5a) D(2) dopamine receptor Homo sapiens 96.2 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635605 346542574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432925 Fc1ccc(cc1)-c1ccc(CN2CCC(CC2)c2ccc3[nH]c(=O)[nH]c3c2)cc1 InChI=1S/C25H24FN3O/c26-22-8-5-19(6-9-22)18-3-1-17(2-4-18)16-29-13-11-20(12-14-29)21-7-10-23-24(15-21)28-25(30)27-23/h1-10,15,20H,11-14,16H2,(H2,27,28,30) VJWKFQAMDOJJDY-UHFFFAOYSA-N 248045 5-(1-((4'-Fluorobiphenyl-4-yl)methyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one (5b) D(2) dopamine receptor Homo sapiens 34.4 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635606 346542575 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432926 O=c1[nH]c2ccc(cc2[nH]1)C1CCN(Cc2cncc(c2)-c2ccccc2)CC1 InChI=1S/C24H24N4O/c29-24-26-22-7-6-20(13-23(22)27-24)19-8-10-28(11-9-19)16-17-12-21(15-25-14-17)18-4-2-1-3-5-18/h1-7,12-15,19H,8-11,16H2,(H2,26,27,29) UWRALPYINZTIEH-UHFFFAOYSA-N 248046 5-(1-((5-phenylpyridin-3-yl)methyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one (5c) D(2) dopamine receptor Homo sapiens 18.5 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635607 346542576 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432927 Fc1ccc(cc1)-c1cncc(CN2CCC(CC2)c2ccc3[nH]c(=O)[nH]c3c2)c1 InChI=1S/C24H23FN4O/c25-21-4-1-17(2-5-21)20-11-16(13-26-14-20)15-29-9-7-18(8-10-29)19-3-6-22-23(12-19)28-24(30)27-22/h1-6,11-14,18H,7-10,15H2,(H2,27,28,30) DLKBFLTUQVFJEB-UHFFFAOYSA-N 248047 5-(1-((5-(4-Fluorophenyl)pyridin-3-yl)methyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one (5d) D(2) dopamine receptor Homo sapiens 24.6 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635608 346542577 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432928 O=c1[nH]c2ccc(cc2[nH]1)C1CCN(Cc2cccc(c2)C2=CCCC2)CC1 InChI=1S/C24H27N3O/c28-24-25-22-9-8-21(15-23(22)26-24)19-10-12-27(13-11-19)16-17-4-3-7-20(14-17)18-5-1-2-6-18/h3-5,7-9,14-15,19H,1-2,6,10-13,16H2,(H2,25,26,28) PZZTZOMXZRXURK-UHFFFAOYSA-N 248048 5-(1-(3-cyclopentenylbenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one (5e) D(2) dopamine receptor Homo sapiens 8.12 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635609 346542578 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432929 O=c1[nH]c2ccc(cc2[nH]1)C1CCN(Cc2cncc(c2)C2=CCCC2)CC1 InChI=1S/C23H26N4O/c28-23-25-21-6-5-19(12-22(21)26-23)18-7-9-27(10-8-18)15-16-11-20(14-24-13-16)17-3-1-2-4-17/h3,5-6,11-14,18H,1-2,4,7-10,15H2,(H2,25,26,28) PWXMEWXNAIZCSF-UHFFFAOYSA-N 248049 5-(1-((5-cyclopentenylpyridin-3-yl)methyl)piperidin-4-yl)-1Hbenzo[d]imidazol-2(3H)-one (5f) D(2) dopamine receptor Homo sapiens 4.26 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635610 346542579 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432930 O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2ccc(cc2)-c2ccccc2)CC1 InChI=1S/C24H24N4O/c29-24-25-22-11-10-21(16-23(22)26-24)28-14-12-27(13-15-28)17-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-11,16H,12-15,17H2,(H2,25,26,29) MBLTZRXRTYIYDI-UHFFFAOYSA-N 248050 5-(4-(biphenyl-4-ylmethyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6a) D(2) dopamine receptor Homo sapiens 42.22 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635611 346542580 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432931 Fc1ccc(cc1)-c1ccc(CN2CCN(CC2)c2ccc3[nH]c(=O)[nH]c3c2)cc1 InChI=1S/C24H23FN4O/c25-20-7-5-19(6-8-20)18-3-1-17(2-4-18)16-28-11-13-29(14-12-28)21-9-10-22-23(15-21)27-24(30)26-22/h1-10,15H,11-14,16H2,(H2,26,27,30) LMYGXBFOAYQRPY-UHFFFAOYSA-N 248051 5-(4-((4'-fluorobiphenyl-4-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6b) D(2) dopamine receptor Homo sapiens 62.6 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635612 346542581 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432932 O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2cncc(c2)-c2ccccc2)CC1 InChI=1S/C23H23N5O/c29-23-25-21-7-6-20(13-22(21)26-23)28-10-8-27(9-11-28)16-17-12-19(15-24-14-17)18-4-2-1-3-5-18/h1-7,12-15H,8-11,16H2,(H2,25,26,29) GHCLCIMAOYUDPI-UHFFFAOYSA-N 248052 5-(4-((5-phenylpyridin-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6c) D(2) dopamine receptor Homo sapiens 12.6 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635613 346542582 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432933 Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccc3[nH]c(=O)[nH]c3c2)c1 InChI=1S/C23H22FN5O/c24-19-3-1-17(2-4-19)18-11-16(13-25-14-18)15-28-7-9-29(10-8-28)20-5-6-21-22(12-20)27-23(30)26-21/h1-6,11-14H,7-10,15H2,(H2,26,27,30) MHESBHYTWIOPAB-UHFFFAOYSA-N 248053 5-(4-((5-(4-fluorophenyl)pyridin-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6d) D(2) dopamine receptor Homo sapiens 82.0 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635614 346542583 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432934 O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2cccc(c2)C2=CCCC2)CC1 InChI=1S/C23H26N4O/c28-23-24-21-9-8-20(15-22(21)25-23)27-12-10-26(11-13-27)16-17-4-3-7-19(14-17)18-5-1-2-6-18/h3-5,7-9,14-15H,1-2,6,10-13,16H2,(H2,24,25,28) ZPRJWVIVUPFMTK-UHFFFAOYSA-N 248054 5-(4-(3-cyclopentenylbenzyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6e) D(2) dopamine receptor Homo sapiens 10.4 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635615 346542584 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 432935 O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2cncc(c2)C2=CCCC2)CC1 InChI=1S/C22H25N5O/c28-22-24-20-6-5-19(12-21(20)25-22)27-9-7-26(8-10-27)15-16-11-18(14-23-13-16)17-3-1-2-4-17/h3,5-6,11-14H,1-2,4,7-10,15H2,(H2,24,25,28) CTRJCSXYHYSJGC-UHFFFAOYSA-N 248055 5-(4-((5-cyclopentenylpyridin-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6f) D(2) dopamine receptor Homo sapiens 3.1 7.4 25.00 C Curated from the literature by BindingDB 10.3109/14756366.2013.776556 10.7270/Q2SN07WV 23488743 aid1803434 Ullah, N King Fahd University of Petroleum & Minerals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248055&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131635616 346542585 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 445381 Cc1ccc2N=C(N3CCN(CC(C)(C)C(O)=O)CC3)c3cc(Cl)sc3Oc2c1 InChI=1S/C21H24ClN3O3S/c1-13-4-5-15-16(10-13)28-19-14(11-17(22)29-19)18(23-15)25-8-6-24(7-9-25)12-21(2,3)20(26)27/h4-5,10-11H,6-9,12H2,1-3H3,(H,26,27) PSYAJOBNPBYKRW-UHFFFAOYSA-N 255474 US9481688, 1::US9481688, 3 D(2) dopamine receptor Homo sapiens 2780 US Patent 10.7270/Q25D8QRW aid1803573 US9481688 Ledgard, AJ Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=255474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=255474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71212556 347830110 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 445388 Cc1ccc2N=C(N3CCN(CC(C)(C)C(O)=O)CC3)c3cc(Cl)sc3Oc2c1 InChI=1S/C21H24ClN3O3S/c1-13-4-5-15-16(10-13)28-19-14(11-17(22)29-19)18(23-15)25-8-6-24(7-9-25)12-21(2,3)20(26)27/h4-5,10-11H,6-9,12H2,1-3H3,(H,26,27) PSYAJOBNPBYKRW-UHFFFAOYSA-N 255474 US9481688, 1::US9481688, 3 D(2) dopamine receptor Homo sapiens >4570 US Patent 10.7270/Q25D8QRW aid1803573 US9481688 Ledgard, AJ Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=255474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=255474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71212556 347830110 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001713 CCOC(=O)C1CCN(CC2COc3ccc4[nH]c(cc4c3O2)C(=O)OC)CC1 InChI=1S/C21H26N2O6/c1-3-27-20(24)13-6-8-23(9-7-13)11-14-12-28-18-5-4-16-15(19(18)29-14)10-17(22-16)21(25)26-2/h4-5,10,13-14,22H,3,6-9,11-12H2,1-2H3 LWBZBWXDCWJUBA-UHFFFAOYSA-N 50001111 8-(4-Ethoxycarbonyl-piperidin-1-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester::CHEMBL319023 D(2) dopamine receptor Homo sapiens 255 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001111&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665505 103915603 CHEMBL319023 ZINC12356310 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001717 COC(=O)c1cc2c3OC(CN4CCC5(CC4)N(CNC5=O)c4ccccc4)COc3ccc2[nH]1 InChI=1S/C26H28N4O5/c1-33-24(31)21-13-19-20(28-21)7-8-22-23(19)35-18(15-34-22)14-29-11-9-26(10-12-29)25(32)27-16-30(26)17-5-3-2-4-6-17/h2-8,13,18,28H,9-12,14-16H2,1H3,(H,27,32) HSOIWCPMXCWYHB-UHFFFAOYSA-N 50001114 8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester::CHEMBL320173 D(2) dopamine receptor Homo sapiens 3.1 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001114&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665503 103915606 CHEMBL320173 ZINC13726388 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001719 CCCCOC(=O)c1cc2c3OC(CN4CCC5(CC4)N(CNC5=O)c4ccccc4)COc3ccc2[nH]1 InChI=1S/C29H34N4O5/c1-2-3-15-36-27(34)24-16-22-23(31-24)9-10-25-26(22)38-21(18-37-25)17-32-13-11-29(12-14-32)28(35)30-19-33(29)20-7-5-4-6-8-20/h4-10,16,21,31H,2-3,11-15,17-19H2,1H3,(H,30,35) GLHCMRRMBLASQA-UHFFFAOYSA-N 50001109 8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid butyl ester::CHEMBL102175 D(2) dopamine receptor Homo sapiens 5.7 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001109&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665509 103915601 CHEMBL102175 ZINC13726411 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001722 O=C(OCc1ccccc1)c1cc2c3OC(CN4CCC5(CC4)N(CNC5=O)c4ccccc4)COc3ccc2[nH]1 InChI=1S/C32H32N4O5/c37-30(40-19-22-7-3-1-4-8-22)27-17-25-26(34-27)11-12-28-29(25)41-24(20-39-28)18-35-15-13-32(14-16-35)31(38)33-21-36(32)23-9-5-2-6-10-23/h1-12,17,24,34H,13-16,18-21H2,(H,33,38) DQQCWQGYIUCCKR-UHFFFAOYSA-N 50001110 8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid benzyl ester::CHEMBL318166 D(2) dopamine receptor Homo sapiens 5.8 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001110&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665510 103915602 CHEMBL318166 ZINC26834941 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001727 OCc1cc2c3OC(CN4CCC5(CC4)N(CNC5=O)c4ccccc4)COc3ccc2[nH]1 InChI=1S/C25H28N4O4/c30-14-17-12-20-21(27-17)6-7-22-23(20)33-19(15-32-22)13-28-10-8-25(9-11-28)24(31)26-16-29(25)18-4-2-1-3-5-18/h1-7,12,19,27,30H,8-11,13-16H2,(H,26,31) UWNQTNJQOXIWHF-UHFFFAOYSA-N 50001112 8-(2-Hydroxymethyl-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalen-8-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL323088 D(2) dopamine receptor Homo sapiens 2 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001112&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665517 103915604 CHEMBL323088 ZINC13726423 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001733 COC(=O)c1cc2c3OC(CNCCCc4ccccc4)COc3ccc2[nH]1 InChI=1S/C22H24N2O4/c1-26-22(25)19-12-17-18(24-19)9-10-20-21(17)28-16(14-27-20)13-23-11-5-8-15-6-3-2-4-7-15/h2-4,6-7,9-10,12,16,23-24H,5,8,11,13-14H2,1H3 NBCYJDUUVPJJKY-UHFFFAOYSA-N 50001117 8-[(3-Phenyl-propylamino)-methyl]-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester::CHEMBL318374 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001117&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9800010 103915609 CHEMBL318374 ZINC03801183 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001745 O=C(NCCCc1ccccc1)c1cc2c3OC(CNCCCc4ccccc4)COc3ccc2[nH]1 InChI=1S/C30H33N3O3/c34-30(32-18-8-14-23-11-5-2-6-12-23)27-19-25-26(33-27)15-16-28-29(25)36-24(21-35-28)20-31-17-7-13-22-9-3-1-4-10-22/h1-6,9-12,15-16,19,24,31,33H,7-8,13-14,17-18,20-21H2,(H,32,34) XAJNHJMBQCJVMY-UHFFFAOYSA-N 50001115 8-[(3-Phenyl-propylamino)-methyl]-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid (3-phenyl-propyl)-amide::CHEMBL103983 D(2) dopamine receptor Homo sapiens 41 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001115&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665516 103915607 CHEMBL103983 ZINC13726444 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001746 NC(=O)c1cc2c3OC(CN4CCC5(CC4)N(CNC5=O)c4ccccc4)COc3ccc2[nH]1 InChI=1S/C25H27N5O4/c26-23(31)20-12-18-19(28-20)6-7-21-22(18)34-17(14-33-21)13-29-10-8-25(9-11-29)24(32)27-15-30(25)16-4-2-1-3-5-16/h1-7,12,17,28H,8-11,13-15H2,(H2,26,31)(H,27,32) VPDXGIUSVBWBOE-UHFFFAOYSA-N 50001113 8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid amide::CHEMBL320880 D(2) dopamine receptor Homo sapiens 1.8 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001113&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665508 103915605 CHEMBL320880 ZINC13726404 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001750 O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccc4[nH]ccc4c3O2)CC1 InChI=1S/C24H26N4O3/c29-23-24(28(16-26-23)17-4-2-1-3-5-17)9-12-27(13-10-24)14-18-15-30-21-7-6-20-19(8-11-25-20)22(21)31-18/h1-8,11,18,25H,9-10,12-16H2,(H,26,29) DVFLWMCCYDDTMA-UHFFFAOYSA-N 50001118 8-(7,8-Dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalen-8-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL317433 D(2) dopamine receptor Homo sapiens 0.200000 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334637 103915610 CHEMBL317433 ZINC12356430 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001757 COC(=O)c1cc2c3OC(CN4CCC(CC4)n4c5ccccc5[nH]c4=O)COc3ccc2[nH]1 InChI=1S/C25H26N4O5/c1-32-24(30)20-12-17-18(26-20)6-7-22-23(17)34-16(14-33-22)13-28-10-8-15(9-11-28)29-21-5-3-2-4-19(21)27-25(29)31/h2-7,12,15-16,26H,8-11,13-14H2,1H3,(H,27,31) BBLSPFIVZYOCKM-UHFFFAOYSA-N 50001116 8-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-ylmethyl]-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester::CHEMBL418802 D(2) dopamine receptor Homo sapiens 6.7 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001116&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334603 103915608 CHEMBL418802 ZINC13726429 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001759 O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccc4[nH]c(cc4c3O2)C#N)CC1 InChI=1S/C25H25N5O3/c26-13-17-12-20-21(28-17)6-7-22-23(20)33-19(15-32-22)14-29-10-8-25(9-11-29)24(31)27-16-30(25)18-4-2-1-3-5-18/h1-7,12,19,28H,8-11,14-16H2,(H,27,31) FMCRANLYZLAXGN-UHFFFAOYSA-N 50001119 8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carbonitrile::CHEMBL101535 D(2) dopamine receptor Homo sapiens 1.5 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9955072 103915611 CHEMBL101535 ZINC53172718 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001761 OC(=O)c1cc2c3OC(CN4CCC5(CC4)N(CNC5=O)c4ccccc4)COc3ccc2[nH]1 InChI=1S/C25H26N4O5/c30-23(31)20-12-18-19(27-20)6-7-21-22(18)34-17(14-33-21)13-28-10-8-25(9-11-28)24(32)26-15-29(25)16-4-2-1-3-5-16/h1-7,12,17,27H,8-11,13-15H2,(H,26,32)(H,30,31) UXGIBVBRPWLFHU-UHFFFAOYSA-N 50001121 8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid::CHEMBL106283 D(2) dopamine receptor Homo sapiens 58 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665507 103915613 CHEMBL106283 ZINC13726396 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50001763 COC(=O)c1cc2c3OC(CN4CCC(CC4)(Nc4ccccc4)C(N)=O)COc3ccc2[nH]1 InChI=1S/C25H28N4O5/c1-32-23(30)20-13-18-19(27-20)7-8-21-22(18)34-17(15-33-21)14-29-11-9-25(10-12-29,24(26)31)28-16-5-3-2-4-6-16/h2-8,13,17,27-28H,9-12,14-15H2,1H3,(H2,26,31) TZWWOCFOYDRGRO-UHFFFAOYSA-N 50001120 8-(4-Carbamoyl-4-phenylamino-piperidin-1-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid methyl ester::CHEMBL101483 D(2) dopamine receptor Homo sapiens >388 ChEMBL 10.1021/jm00094a021 10.7270/Q21835G5 1323682 Ennis, MD; Baze, ME; Smith, MW; Lawson, CF; McCall, RB; Lahti, RA; Piercey, MF Upjohn Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15665506 103915612 CHEMBL101483 ZINC13726436 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50002080 O=C1CC2(CCC(CC2)OCc2ccccc2)OC=C1c1ccccc1 InChI=1S/C23H24O3/c24-22-15-23(26-17-21(22)19-9-5-2-6-10-19)13-11-20(12-14-23)25-16-18-7-3-1-4-8-18/h1-10,17,20H,11-16H2 INMMDUIABIZQGC-UHFFFAOYSA-N 50281456 9-Benzyloxy-3-phenyl-1-oxa-spiro[5.5]undec-2-en-4-one::CHEMBL72539 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/S0960-894X(01)80880-5 10.7270/Q2571BX6 Schow, SR; Tam, SW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44311180 104123130 CHEMBL72539 ZINC26297039 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50003346 Fc1ccc(cc1)[Si]1(CCC(C1)N1CCN(CC1)c1ccccc1)c1ccc(F)cc1 InChI=1S/C26H28F2N2Si/c27-21-6-10-25(11-7-21)31(26-12-8-22(28)9-13-26)19-14-24(20-31)30-17-15-29(16-18-30)23-4-2-1-3-5-23/h1-13,24H,14-20H2 SUBRNIMHHUWIJU-UHFFFAOYSA-N 50283920 1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-phenyl-piperazine::CHEMBL134423 D(2) dopamine receptor Homo sapiens 100 ChEMBL 10.1016/0960-894X(94)80007-3 10.7270/Q2HX1D6M Damour, D; Barreau, M; Dutruc-Rosset, G; Doble, A; Piot, O; Mignani, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9889149 104125577 CHEMBL134423 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009751 Clc1ccc(cc1)N1CCN(Cc2cc[nH]c2C=C(C#N)C#N)CC1 InChI=1S/C19H18ClN5/c20-17-1-3-18(4-2-17)25-9-7-24(8-10-25)14-16-5-6-23-19(16)11-15(12-21)13-22/h1-6,11,23H,7-10,14H2 RCACIEKJQOIDQV-UHFFFAOYSA-N 50079641 2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile::CHEMBL300553 D(2) dopamine receptor Homo sapiens 8950 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467373 103971783 CHEMBL300553 ZINC36216457 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50007647 OC[C@H]1O[C@H](Oc2ccc(CC3NCCc4cc(O)c(O)cc34)cc2)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C22H27NO8/c24-10-18-19(27)20(28)21(29)22(31-18)30-13-3-1-11(2-4-13)7-15-14-9-17(26)16(25)8-12(14)5-6-23-15/h1-4,8-9,15,18-29H,5-7,10H2/t15?,18-,19+,20-,21-,22+/m1/s1 OEUGQYOMKCJJLJ-LCSWDSHXSA-N 50450614 CHEMBL2303762 D(2) dopamine receptor Homo sapiens 2420 ChEMBL 10.1016/S0960-894X(97)00194-7 10.7270/Q2CJ8F0Z Hegde, VR; Dai, P; Ladislaw, C; Patel, MG; Puar, MS; Pachter, JA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71717830 225145152 CHEMBL2303762 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50007035 Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccs3)CC2)c1Cl InChI=1S/C23H29Cl2N3OS/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18- KJOFXQKVGTXQTK-IYARVYRRSA-N 50290221 CHEMBL80919::Thiophene-2-carboxylic acid (4-{2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amide D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1016/S0960-894X(97)00443-5 10.7270/Q27W6CQ0 Belliotti, TR; Kesten, SR; Rubin, JR; Wustrow, DJ; Georgic, LM; Zoski, KT; Akunne, HC; Wise, LD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9847363 104131773 CHEMBL80919 ZINC01485407 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50007038 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)C1CCCCC1 InChI=1S/C25H39N3O/c29-25(22-7-3-1-4-8-22)26-23-13-11-21(12-14-23)15-16-27-17-19-28(20-18-27)24-9-5-2-6-10-24/h2,5-6,9-10,21-23H,1,3-4,7-8,11-20H2,(H,26,29)/t21-,23- XOMRUHWGUJNGLC-AFARHQOCSA-N 50063279 CHEMBL309623::Cyclohexanecarboxylic acid {4-[2-(4-phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-amide D(2) dopamine receptor Homo sapiens 38 ChEMBL 10.1016/S0960-894X(97)00443-5 10.7270/Q27W6CQ0 Belliotti, TR; Kesten, SR; Rubin, JR; Wustrow, DJ; Georgic, LM; Zoski, KT; Akunne, HC; Wise, LD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865584 103958610 CHEMBL309623 ZINC00601694 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010937 C(Cc1c[nH]c2ncccc12)N1CCC(\C=C\c2ccccc2)=CC1 InChI=1S/C22H23N3/c1-2-5-18(6-3-1)8-9-19-10-14-25(15-11-19)16-12-20-17-24-22-21(20)7-4-13-23-22/h1-10,13,17H,11-12,14-16H2,(H,23,24)/b9-8+ XVYIADYYFNGCJZ-CMDGGOBGSA-N 50450987 CHEMBL2112913 D(2) dopamine receptor Homo sapiens 280 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71458040 225145225 CHEMBL2112913 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010938 C(Cc1c[nH]c2ncccc12)N1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c1-2-5-16(6-3-1)17-8-12-23(13-9-17)14-10-18-15-22-20-19(18)7-4-11-21-20/h1-8,11,15H,9-10,12-14H2,(H,21,22) RRNSUOWXTVZIKJ-UHFFFAOYSA-N 50450988 CHEMBL2112912 D(2) dopamine receptor Homo sapiens 21 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450988&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10335148 225145226 CHEMBL2112912 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009866 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 1.9 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009867 CCCN(CCC)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-9-10-16-14(13-15)7-6-8-17(16)19-3/h6-8,15H,4-5,9-13H2,1-3H3/t15-/m1/s1 HQGWTXXZVBZBPH-OAHLLOKOSA-N 50080053 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL68573 D(2) dopamine receptor Homo sapiens 6.4 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308898 103980244 CHEMBL68573 ZINC13759795 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009868 CCCN(Cc1cccs1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C19H25NOS/c1-3-11-20(14-17-7-5-12-22-17)16-9-10-18-15(13-16)6-4-8-19(18)21-2/h4-8,12,16H,3,9-11,13-14H2,1-2H3/t16-/m1/s1 QEYDMNFIIPJGKU-MRXNPFEDSA-N 50080049 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-thiophen-2-ylmethyl-amine::CHEMBL69706 D(2) dopamine receptor Homo sapiens 152 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308839 103980240 CHEMBL69706 ZINC26271640 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009869 CCCN(Cc1ccco1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C19H25NO2/c1-3-11-20(14-17-7-5-12-22-17)16-9-10-18-15(13-16)6-4-8-19(18)21-2/h4-8,12,16H,3,9-11,13-14H2,1-2H3/t16-/m1/s1 WAKZRNAHRQKOQJ-MRXNPFEDSA-N 50080052 CHEMBL303502::Furan-2-ylmethyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine D(2) dopamine receptor Homo sapiens 125 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309058 103980243 CHEMBL303502 ZINC26265987 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009870 COc1cccc2C[C@@H](CCc12)N(Cc1ccccc1)Cc1ccccc1 InChI=1S/C25H27NO/c1-27-25-14-8-13-22-17-23(15-16-24(22)25)26(18-20-9-4-2-5-10-20)19-21-11-6-3-7-12-21/h2-14,23H,15-19H2,1H3/t23-/m1/s1 MNNMWEOINNJPCF-HSZRJFAPSA-N 50080054 CHEMBL69705::Dibenzyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22082742 103980245 CHEMBL69705 ZINC26271634 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009871 CCCN(Cc1ccc(F)cc1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C21H26FNO/c1-3-13-23(15-16-7-9-18(22)10-8-16)19-11-12-20-17(14-19)5-4-6-21(20)24-2/h4-10,19H,3,11-15H2,1-2H3/t19-/m1/s1 NBGVZXIBORQZMS-LJQANCHMSA-N 50080048 (4-Fluoro-benzyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL71599 D(2) dopamine receptor Homo sapiens 70 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309076 103980239 CHEMBL71599 ZINC26283574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009872 CCCN(Cc1ccccc1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C21H27NO/c1-3-14-22(16-17-8-5-4-6-9-17)19-12-13-20-18(15-19)10-7-11-21(20)23-2/h4-11,19H,3,12-16H2,1-2H3/t19-/m1/s1 JZLLENPQJVOGOX-LJQANCHMSA-N 50080051 Benzyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL68545 D(2) dopamine receptor Homo sapiens 75 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10063953 103980242 CHEMBL68545 ZINC26268399 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009873 CCCN(Cc1ccc(cc1)[N+]([O-])=O)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C21H26N2O3/c1-3-13-22(15-16-7-9-18(10-8-16)23(24)25)19-11-12-20-17(14-19)5-4-6-21(20)26-2/h4-10,19H,3,11-15H2,1-2H3/t19-/m1/s1 OQFVFESDHDATCZ-LJQANCHMSA-N 50080050 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-(4-nitro-benzyl)-propyl-amine::CHEMBL433121 D(2) dopamine receptor Homo sapiens 59 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9975434 103980241 CHEMBL433121 ZINC26277457 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009874 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.440000 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009875 CCCN(CCC)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C16H24FN/c1-3-10-18(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)17/h5-7,14H,3-4,8-12H2,1-2H3/t14-/m1/s1 WFENTJXFRAVXHY-CQSZACIVSA-N 50053670 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine; hydrochloride::CHEMBL541858::CHEMBL69985 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10729313 103950349 CHEMBL69985CHEMBL541858 ZINC13759323 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009876 CCCN(Cc1ccc(OC)cc1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C22H29NO2/c1-4-14-23(16-17-8-11-20(24-2)12-9-17)19-10-13-21-18(15-19)6-5-7-22(21)25-3/h5-9,11-12,19H,4,10,13-16H2,1-3H3/t19-/m1/s1 JAUQVGAQEBWHPG-LJQANCHMSA-N 50080047 (4-Methoxy-benzyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL67923 D(2) dopamine receptor Homo sapiens 64 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309005 103980238 CHEMBL67923 ZINC26279039 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009877 CCCN[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C14H21NO/c1-3-9-15-12-7-8-13-11(10-12)5-4-6-14(13)16-2/h4-6,12,15H,3,7-10H2,1-2H3/t12-/m1/s1 ICJPCRXVYMMSJY-GFCCVEGCSA-N 50080055 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL71275 D(2) dopamine receptor Homo sapiens 114 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080055&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10656511 103980246 CHEMBL71275 ZINC13759787 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009878 CCCN(Cc1ccccc1)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C20H24FN/c1-2-13-22(15-16-7-4-3-5-8-16)18-11-12-19-17(14-18)9-6-10-20(19)21/h3-10,18H,2,11-15H2,1H3/t18-/m1/s1 IZRKKTGXKLIJDE-GOSISDBHSA-N 50054337 Benzyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL65847 D(2) dopamine receptor Homo sapiens 179 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402380 103950987 CHEMBL65847 ZINC13760017 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009879 COc1cccc2C[C@@H](CCc12)NCc1ccccc1 InChI=1S/C18H21NO/c1-20-18-9-5-8-15-12-16(10-11-17(15)18)19-13-14-6-3-2-4-7-14/h2-9,16,19H,10-13H2,1H3/t16-/m1/s1 OZFLGQHJVWSALN-MRXNPFEDSA-N 50080056 Benzyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine::CHEMBL65896 D(2) dopamine receptor Homo sapiens 1310 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080056&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12280565 103980247 CHEMBL65896 ZINC26265994 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577224 O=C(NCCCCN1CCc2ccccc2C1)c1ccc(cc1)-c1ccccc1 InChI=1S/C26H28N2O/c29-26(24-14-12-23(13-15-24)21-8-2-1-3-9-21)27-17-6-7-18-28-19-16-22-10-4-5-11-25(22)20-28/h1-5,8-15H,6-7,16-20H2,(H,27,29) IJPGGHONVGTCOX-UHFFFAOYSA-N 50217153 CHEMBL53833 D(2) dopamine receptor Homo sapiens 501 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217153&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297458 376225155 CHEMBL53833 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577226 FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3ccc4[nH]ccc4c3)Cc2c1 InChI=1S/C25H26F3N3O4S/c26-25(27,28)36(33,34)35-22-6-5-19-10-14-31(17-21(19)16-22)13-2-1-11-30-24(32)8-4-18-3-7-23-20(15-18)9-12-29-23/h3-9,12,15-16,29H,1-2,10-11,13-14,17H2,(H,30,32)/b8-4+ MFVZCUGAIPDSAL-XBXARRHUSA-N 50217155 CHEMBL291545 D(2) dopamine receptor Homo sapiens 200 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217155&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21973550 376225157 CHEMBL291545 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577228 Oc1ccc2cc(\C=C\C(=O)NCCCCN3CCc4ccc(OS(=O)(=O)C(F)(F)F)cc4C3)ccc2n1 InChI=1S/C26H26F3N3O5S/c27-26(28,29)38(35,36)37-22-7-5-19-11-14-32(17-21(19)16-22)13-2-1-12-30-24(33)9-4-18-3-8-23-20(15-18)6-10-25(34)31-23/h3-10,15-16H,1-2,11-14,17H2,(H,30,33)(H,31,34)/b9-4+ SJAPPPAALBAIBC-RUDMXATFSA-N 50217156 CHEMBL52466 D(2) dopamine receptor Homo sapiens 158 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217156&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297514 376225158 CHEMBL52466 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577230 FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3ccc4ccccc4c3)Cc2c1 InChI=1S/C27H27F3N2O4S/c28-27(29,30)37(34,35)36-25-11-10-22-13-16-32(19-24(22)18-25)15-4-3-14-31-26(33)12-8-20-7-9-21-5-1-2-6-23(21)17-20/h1-2,5-12,17-18H,3-4,13-16,19H2,(H,31,33)/b12-8+ YFRPYRGBQBMLTB-XYOKQWHBSA-N 50217158 CHEMBL55840 D(2) dopamine receptor Homo sapiens 1000 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297390 376225160 CHEMBL55840 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577234 Cc1cc(ccc1-c1ccccc1)C(=O)NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1 InChI=1S/C28H29F3N2O4S/c1-20-17-23(10-12-26(20)22-7-3-2-4-8-22)27(34)32-14-5-6-15-33-16-13-21-9-11-25(18-24(21)19-33)37-38(35,36)28(29,30)31/h2-4,7-12,17-18H,5-6,13-16,19H2,1H3,(H,32,34) JTAWXZPSQGLYQG-UHFFFAOYSA-N 50217157 CHEMBL54948 D(2) dopamine receptor Homo sapiens 1000 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217157&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297720 376225159 CHEMBL54948 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577235 FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C/c3ccccc3)Cc2c1 InChI=1S/C23H25F3N2O4S/c24-23(25,26)33(30,31)32-21-10-9-19-12-15-28(17-20(19)16-21)14-5-4-13-27-22(29)11-8-18-6-2-1-3-7-18/h1-3,6-11,16H,4-5,12-15,17H2,(H,27,29)/b11-8- QZPFGFWFHKJBJX-FLIBITNWSA-N 50217162 CHEMBL55524 D(2) dopamine receptor Homo sapiens 316 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217162&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297472 376225164 CHEMBL55524 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577236 COc1ccc(\C=C\C(=O)NCCCCN2CCc3ccc(OS(=O)(=O)C(F)(F)F)cc3C2)cc1 InChI=1S/C24H27F3N2O5S/c1-33-21-8-4-18(5-9-21)6-11-23(30)28-13-2-3-14-29-15-12-19-7-10-22(16-20(19)17-29)34-35(31,32)24(25,26)27/h4-11,16H,2-3,12-15,17H2,1H3,(H,28,30)/b11-6+ YTBUMNNIZGPKLZ-IZZDOVSWSA-N 50217163 CHEMBL52987 D(2) dopamine receptor Homo sapiens 316 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217163&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17866249 376225165 CHEMBL52987 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577237 COc1cccc(\C=C\C(=O)NCCCCN2CCc3ccc(OS(=O)(=O)C(F)(F)F)cc3C2)c1 InChI=1S/C24H27F3N2O5S/c1-33-21-6-4-5-18(15-21)7-10-23(30)28-12-2-3-13-29-14-11-19-8-9-22(16-20(19)17-29)34-35(31,32)24(25,26)27/h4-10,15-16H,2-3,11-14,17H2,1H3,(H,28,30)/b10-7+ IAMMMQJIUFFPMO-JXMROGBWSA-N 50217164 CHEMBL416842 D(2) dopamine receptor Homo sapiens 316 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217164&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17866237 376225166 CHEMBL416842 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577238 CC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1 InChI=1S/C29H29F3N2O5S/c1-20(35)21-4-6-22(7-5-21)23-8-10-25(11-9-23)28(36)33-15-2-3-16-34-17-14-24-12-13-27(18-26(24)19-34)39-40(37,38)29(30,31)32/h4-13,18H,2-3,14-17,19H2,1H3,(H,33,36) JBETURIRTKWRDW-UHFFFAOYSA-N 50217165 CHEMBL367129 D(2) dopamine receptor Homo sapiens 200 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18797033 376225167 CHEMBL367129 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577239 Cc1ccccc1-c1ccc(cc1)C(=O)NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1 InChI=1S/C28H29F3N2O4S/c1-20-6-2-3-7-26(20)22-8-10-23(11-9-22)27(34)32-15-4-5-16-33-17-14-21-12-13-25(18-24(21)19-33)37-38(35,36)28(29,30)31/h2-3,6-13,18H,4-5,14-17,19H2,1H3,(H,32,34) ZLRJVNFLDHERMS-UHFFFAOYSA-N 50217159 CHEMBL54715 D(2) dopamine receptor Homo sapiens 1585 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297596 376225161 CHEMBL54715 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011203 N[C@H]1CCCC[C@@H]1NC(=O)c1c2N[C@@H]3CCCC[C@H]3Nc2c2C(=O)c3ccccc3-c3ncnc1c23 InChI=1S/C28H30N6O2/c29-16-9-3-4-10-17(16)34-28(36)22-24-20-21(25-26(22)33-19-12-6-5-11-18(19)32-25)27(35)15-8-2-1-7-14(15)23(20)30-13-31-24/h1-2,7-8,13,16-19,32-33H,3-6,9-12,29H2,(H,34,36)/t16-,17-,18+,19+/m0/s1 PYMJARYEQYKRFZ-INDMIFKZSA-N 50403726 CHEMBL2112936 D(2) dopamine receptor Homo sapiens 3200 ChEMBL 10.1016/s0960-894x(99)00075-x 10.7270/Q2TD9WJJ 10201844 Luthin, DR; Rabinovich, AK; Bhumralkar, DR; Youngblood, KL; Bychowski, RA; Dhanoa, DS; May, JM Agouron Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15381051 163352750 CHEMBL2112936 ZINC00580707 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577243 Cc1nnc(o1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1 InChI=1S/C30H29F3N4O5S/c1-20-35-36-29(41-20)25-10-6-22(7-11-25)21-4-8-24(9-5-21)28(38)34-15-2-3-16-37-17-14-23-12-13-27(18-26(23)19-37)42-43(39,40)30(31,32)33/h4-13,18H,2-3,14-17,19H2,1H3,(H,34,38) OXRRNHYMIXLDFY-UHFFFAOYSA-N 50217169 CHEMBL279925 D(2) dopamine receptor Homo sapiens 100 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297694 376225171 CHEMBL279925 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577245 FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3c[nH]c4ccccc34)Cc2c1 InChI=1S/C25H26F3N3O4S/c26-25(27,28)36(33,34)35-21-9-7-18-11-14-31(17-20(18)15-21)13-4-3-12-29-24(32)10-8-19-16-30-23-6-2-1-5-22(19)23/h1-2,5-10,15-16,30H,3-4,11-14,17H2,(H,29,32)/b10-8+ AFKRYMMWFODFAD-CSKARUKUSA-N 50217168 CHEMBL301475 D(2) dopamine receptor Homo sapiens 631 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22132503 376225170 CHEMBL301475 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577246 FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3ccc4ncccc4c3)Cc2c1 InChI=1S/C26H26F3N3O4S/c27-26(28,29)37(34,35)36-23-8-7-20-11-15-32(18-22(20)17-23)14-2-1-12-31-25(33)10-6-19-5-9-24-21(16-19)4-3-13-30-24/h3-10,13,16-17H,1-2,11-12,14-15,18H2,(H,31,33)/b10-6+ PCVICCVMMOFTLF-UXBLZVDNSA-N 50217160 CHEMBL52468 D(2) dopamine receptor Homo sapiens 251 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217160&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297323 376225162 CHEMBL52468 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577247 CNC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1 InChI=1S/C29H30F3N3O5S/c1-33-27(36)23-8-4-20(5-9-23)21-6-10-24(11-7-21)28(37)34-15-2-3-16-35-17-14-22-12-13-26(18-25(22)19-35)40-41(38,39)29(30,31)32/h4-13,18H,2-3,14-17,19H2,1H3,(H,33,36)(H,34,37) AUFOWYXFFKBIDT-UHFFFAOYSA-N 50217171 CHEMBL54777 D(2) dopamine receptor Homo sapiens 100 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17895586 376225173 CHEMBL54777 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577251 FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3cnc4ccccc4c3)Cc2c1 InChI=1S/C26H26F3N3O4S/c27-26(28,29)37(34,35)36-23-9-8-20-11-14-32(18-22(20)16-23)13-4-3-12-30-25(33)10-7-19-15-21-5-1-2-6-24(21)31-17-19/h1-2,5-10,15-17H,3-4,11-14,18H2,(H,30,33)/b10-7+ WIWLEFDYNDBBIF-JXMROGBWSA-N 50217166 CHEMBL52901 D(2) dopamine receptor Homo sapiens 316 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17866221 376225168 CHEMBL52901 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577254 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(Cl)cccc2C1 InChI=1S/C30H35ClN2O/c1-2-20-33(27-17-18-28-26(22-27)11-8-12-29(28)31)21-7-6-19-32-30(34)25-15-13-24(14-16-25)23-9-4-3-5-10-23/h3-5,8-16,27H,2,6-7,17-22H2,1H3,(H,32,34) KSCIAWWFBYAELA-UHFFFAOYSA-N 50000027 CHEMBL51977 D(2) dopamine receptor Homo sapiens 398 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9912796 103914726 CHEMBL51977 ZINC95548026 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577256 CC(=O)c1cccc(\C=C\C(=O)NCCCCN2CCc3ccc(OS(=O)(=O)C(F)(F)F)cc3C2)c1 InChI=1S/C25H27F3N2O5S/c1-18(31)21-6-4-5-19(15-21)7-10-24(32)29-12-2-3-13-30-14-11-20-8-9-23(16-22(20)17-30)35-36(33,34)25(26,27)28/h4-10,15-16H,2-3,11-14,17H2,1H3,(H,29,32)/b10-7+ NUWDDLFERGKQRG-JXMROGBWSA-N 50217161 CHEMBL52135 D(2) dopamine receptor Homo sapiens 398 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217161&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17866242 376225163 CHEMBL52135 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577258 FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3ccc4ccccc4n3)Cc2c1 InChI=1S/C26H26F3N3O4S/c27-26(28,29)37(34,35)36-23-11-8-19-13-16-32(18-21(19)17-23)15-4-3-14-30-25(33)12-10-22-9-7-20-5-1-2-6-24(20)31-22/h1-2,5-12,17H,3-4,13-16,18H2,(H,30,33)/b12-10+ NNMGGNROJQCPDV-ZRDIBKRKSA-N 50217173 CHEMBL55090 D(2) dopamine receptor Homo sapiens 398 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17866241 376225175 CHEMBL55090 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011280 COc1ccc(Br)cc1C(=O)NC[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C20H23BrN2O2/c1-25-19-8-7-17(21)11-18(19)20(24)22-12-16-9-10-23(14-16)13-15-5-3-2-4-6-15/h2-8,11,16H,9-10,12-14H2,1H3,(H,22,24)/t16-/m1/s1 YBRBKCXISVCUJG-MRXNPFEDSA-N 50076034 CHEMBL423440::N-((R)-1-Benzyl-pyrrolidin-3-ylmethyl)-5-bromo-2-methoxy-benzamide D(2) dopamine receptor Homo sapiens 2000 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001207 103969030 CHEMBL423440 ZINC27977451 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011293 CNc1cc(OC)c(cc1Cl)C(=O)NC[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C21H26ClN3O2/c1-23-19-11-20(27-2)17(10-18(19)22)21(26)24-12-16-8-9-25(14-16)13-15-6-4-3-5-7-15/h3-7,10-11,16,23H,8-9,12-14H2,1-2H3,(H,24,26)/t16-/m0/s1 QBCMSAVCLXLVLP-INIZCTEOSA-N 50076032 CHEMBL169222::N-((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 58 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380715 103969028 CHEMBL169222 ZINC27984958 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011295 COc1ccc(Br)cc1C(=O)NC[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C20H23BrN2O2/c1-25-19-8-7-17(21)11-18(19)20(24)22-12-16-9-10-23(14-16)13-15-5-3-2-4-6-15/h2-8,11,16H,9-10,12-14H2,1H3,(H,22,24)/t16-/m0/s1 YBRBKCXISVCUJG-INIZCTEOSA-N 50076033 CHEMBL353090::N-((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-5-bromo-2-methoxy-benzamide D(2) dopamine receptor Homo sapiens 1600 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380816 103969029 CHEMBL353090 ZINC27985122 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011307 CNc1cc(OC)c(cc1Cl)C(=O)NC[C@H]1CN(Cc2ccccc2)C[C@H]1C InChI=1S/C22H28ClN3O2/c1-15-12-26(13-16-7-5-4-6-8-16)14-17(15)11-25-22(27)18-9-19(23)20(24-2)10-21(18)28-3/h4-10,15,17,24H,11-14H2,1-3H3,(H,25,27)/t15-,17+/m1/s1 RVBDWZKWSXQLMF-WBVHZDCISA-N 50076027 CHEMBL169193::N-((3S,4S)-1-Benzyl-4-methyl-pyrrolidin-3-ylmethyl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 79 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380815 103969023 CHEMBL169193 ZINC27985117 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011308 COc1cc(N)c(Cl)cc1C(=O)NC[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C20H24ClN3O2/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-11-15-7-8-24(13-15)12-14-5-3-2-4-6-14/h2-6,9-10,15H,7-8,11-13,22H2,1H3,(H,23,25)/t15-/m1/s1 XZPQRIJZBKZROM-OAHLLOKOSA-N 50076036 4-Amino-N-((R)-1-benzyl-pyrrolidin-3-ylmethyl)-5-chloro-2-methoxy-benzamide::CHEMBL168566 D(2) dopamine receptor Homo sapiens 540 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380685 103969032 CHEMBL168566 ZINC27901384 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011311 COc1cc(NC(C)=O)c(Cl)cc1C(=O)NC[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C22H26ClN3O3/c1-15(27)25-20-11-21(29-2)18(10-19(20)23)22(28)24-12-17-8-9-26(14-17)13-16-6-4-3-5-7-16/h3-7,10-11,17H,8-9,12-14H2,1-2H3,(H,24,28)(H,25,27)/t17-/m1/s1 FUZBDAGWGHASHR-QGZVFWFLSA-N 50076031 4-Acetylamino-N-((R)-1-benzyl-pyrrolidin-3-ylmethyl)-5-chloro-2-methoxy-benzamide::CHEMBL167032 D(2) dopamine receptor Homo sapiens 25000 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381117 103969027 CHEMBL167032 ZINC27895174 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011312 CNc1cc(OC)c(cc1Cl)C(=O)NC[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C21H26ClN3O2/c1-23-19-11-20(27-2)17(10-18(19)22)21(26)24-12-16-8-9-25(14-16)13-15-6-4-3-5-7-15/h3-7,10-11,16,23H,8-9,12-14H2,1-2H3,(H,24,26)/t16-/m1/s1 QBCMSAVCLXLVLP-MRXNPFEDSA-N 50076026 CHEMBL166587::N-((R)-1-Benzyl-pyrrolidin-3-ylmethyl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 86 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381118 103969022 CHEMBL166587 ZINC27895179 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011316 CNc1cc(OC)c(cc1Cl)C(=O)NC[C@@H]1CN(Cc2ccccc2)C[C@H]1C InChI=1S/C22H28ClN3O2/c1-15-12-26(13-16-7-5-4-6-8-16)14-17(15)11-25-22(27)18-9-19(23)20(24-2)10-21(18)28-3/h4-10,15,17,24H,11-14H2,1-3H3,(H,25,27)/t15-,17-/m1/s1 RVBDWZKWSXQLMF-NVXWUHKLSA-N 50076039 CHEMBL354180::N-((3R,4S)-1-Benzyl-4-methyl-pyrrolidin-3-ylmethyl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380774 103969035 CHEMBL354180 ZINC27983874 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011317 CCC[C@H]1CN(Cc2ccccc2)C[C@H]1CNC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C24H32ClN3O2/c1-4-8-18-15-28(14-17-9-6-5-7-10-17)16-19(18)13-27-24(29)20-11-21(25)22(26-2)12-23(20)30-3/h5-7,9-12,18-19,26H,4,8,13-16H2,1-3H3,(H,27,29)/t18-,19+/m0/s1 FPHFICIJDHPAHE-RBUKOAKNSA-N 50076037 CHEMBL168611::N-((3R,4R)-1-Benzyl-4-propyl-pyrrolidin-3-ylmethyl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 45 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10432808 103969033 CHEMBL168611 ZINC27983095 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011318 CNc1cc(OC)c(cc1Cl)C(=O)NC[C@H]1CN(Cc2ccccc2)C[C@@H]1C InChI=1S/C22H28ClN3O2/c1-15-12-26(13-16-7-5-4-6-8-16)14-17(15)11-25-22(27)18-9-19(23)20(24-2)10-21(18)28-3/h4-10,15,17,24H,11-14H2,1-3H3,(H,25,27)/t15-,17-/m0/s1 RVBDWZKWSXQLMF-RDJZCZTQSA-N 50076030 CHEMBL413343::N-((3S,4R)-1-Benzyl-4-methyl-pyrrolidin-3-ylmethyl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 330 ChEMBL 10.1016/s0960-894x(99)00086-4 10.7270/Q2B27VT5 10206547 Thomas, C; Hubner, H; Gmeiner, P Universit£t Erlangen-N£rnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380802 103969026 CHEMBL413343 ZINC27902095 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012432 COc1ccc(Br)cc1-c1nc(CNCCC2CCN(Cc3ccccc3)C2)co1 InChI=1S/C24H28BrN3O2/c1-29-23-8-7-20(25)13-22(23)24-27-21(17-30-24)14-26-11-9-19-10-12-28(16-19)15-18-5-3-2-4-6-18/h2-8,13,17,19,26H,9-12,14-16H2,1H3 PUTIADDALKYHRM-UHFFFAOYSA-N 50451098 CHEMBL2111527 D(2) dopamine receptor Homo sapiens 310 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451098&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71457956 225145246 CHEMBL2111527 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012435 COc1ccc(Br)cc1-c1nc(CNC2CCN(Cc3ccccc3)C2)co1 InChI=1S/C22H24BrN3O2/c1-27-21-8-7-17(23)11-20(21)22-25-19(15-28-22)12-24-18-9-10-26(14-18)13-16-5-3-2-4-6-16/h2-8,11,15,18,24H,9-10,12-14H2,1H3 NPLOIWFMUHLKNW-UHFFFAOYSA-N 50451097 CHEMBL2111526 D(2) dopamine receptor Homo sapiens 6600 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451097&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71449034 225145245 CHEMBL2111526 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012441 COc1ccc(Br)cc1-c1nc(CNCC2CCN(Cc3ccccc3)C2)cs1 InChI=1S/C23H26BrN3OS/c1-28-22-8-7-19(24)11-21(22)23-26-20(16-29-23)13-25-12-18-9-10-27(15-18)14-17-5-3-2-4-6-17/h2-8,11,16,18,25H,9-10,12-15H2,1H3 FYSSSSIVDTYBFD-UHFFFAOYSA-N 50451099 CHEMBL2111528 D(2) dopamine receptor Homo sapiens 92 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451099&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454405 225145247 CHEMBL2111528 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012443 C(NCc1csc(n1)-c1ccccc1)[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C22H25N3S/c1-3-7-18(8-4-1)15-25-12-11-19(16-25)13-23-14-21-17-26-22(24-21)20-9-5-2-6-10-20/h1-10,17,19,23H,11-16H2/t19-/m0/s1 UIRIJSKPTMDRCG-IBGZPJMESA-N 50091908 ((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-(2-phenyl-thiazol-4-ylmethyl)-amine::CHEMBL59749 D(2) dopamine receptor Homo sapiens 5050 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091908&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304652 103990128 CHEMBL59749 ZINC26162163 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012445 COc1ccc(Br)cc1-c1nc(CNCC2CCN(Cc3ccccc3)C2)co1 InChI=1S/C23H26BrN3O2/c1-28-22-8-7-19(24)11-21(22)23-26-20(16-29-23)13-25-12-18-9-10-27(15-18)14-17-5-3-2-4-6-17/h2-8,11,16,18,25H,9-10,12-15H2,1H3 HKAWCIGAEVMZGN-UHFFFAOYSA-N 50451096 CHEMBL2111525 D(2) dopamine receptor Homo sapiens 210 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451096&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71450812 225145244 CHEMBL2111525 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012447 COc1ccc(Br)cc1-c1nc(CNC2CCN(Cc3ccccc3)CC2)co1 InChI=1S/C23H26BrN3O2/c1-28-22-8-7-18(24)13-21(22)23-26-20(16-29-23)14-25-19-9-11-27(12-10-19)15-17-5-3-2-4-6-17/h2-8,13,16,19,25H,9-12,14-15H2,1H3 MLHOXJCQVSTIML-UHFFFAOYSA-N 50091902 (1-Benzyl-piperidin-4-yl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine::CHEMBL293225 D(2) dopamine receptor Homo sapiens 630 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091902&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12050199 103990122 CHEMBL293225 ZINC26163415 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50577260 FC(F)(F)S(=O)(=O)Oc1ccc2CCN(CCCCNC(=O)\C=C\c3ccccc3)Cc2c1 InChI=1S/C23H25F3N2O4S/c24-23(25,26)33(30,31)32-21-10-9-19-12-15-28(17-20(19)16-21)14-5-4-13-27-22(29)11-8-18-6-2-1-3-7-18/h1-3,6-11,16H,4-5,12-15,17H2,(H,27,29)/b11-8+ QZPFGFWFHKJBJX-DHZHZOJOSA-N 50217174 CHEMBL55276 D(2) dopamine receptor Homo sapiens 316 ChEMBL 10.1016/s0960-894x(98)00699-4 10.7270/Q2057J4D 10021923 Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Coldwell, MC; Hadley, MS; Jeffrey, P; Johns, A; Johnson, CN; Nash, DJ; Riley, GJ; Smith, SA; Stacey, RC; Stemp, G; Thewlis, KM; Vong, AK SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17866228 376225176 CHEMBL55276 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012453 C(N1CCN(CC1)c1ccccc1)c1coc(n1)-c1ccccc1 InChI=1S/C20H21N3O/c1-3-7-17(8-4-1)20-21-18(16-24-20)15-22-11-13-23(14-12-22)19-9-5-2-6-10-19/h1-10,16H,11-15H2 YJLMHUBBYHISAU-UHFFFAOYSA-N 50091894 1-Phenyl-4-(2-phenyl-oxazol-4-ylmethyl)-piperazine::CHEMBL294780 D(2) dopamine receptor Homo sapiens 3000 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091894&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12049520 103990114 CHEMBL294780 ZINC12534453 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012455 COc1ccc(Br)cc1-c1nc(CNC2CCN(Cc3ccccc3)CC2)cs1 InChI=1S/C23H26BrN3OS/c1-28-22-8-7-18(24)13-21(22)23-26-20(16-29-23)14-25-19-9-11-27(12-10-19)15-17-5-3-2-4-6-17/h2-8,13,16,19,25H,9-12,14-15H2,1H3 PGWQCIREQLHHHR-UHFFFAOYSA-N 50091895 (1-Benzyl-piperidin-4-yl)-[2-(5-bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-amine::CHEMBL62624 D(2) dopamine receptor Homo sapiens 105 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091895&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12050201 103990115 CHEMBL62624 ZINC26172282 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012458 C(N1CCN(Cc2ccccc2)CC1)c1coc(n1)-c1ccccc1 InChI=1S/C21H23N3O/c1-3-7-18(8-4-1)15-23-11-13-24(14-12-23)16-20-17-25-21(22-20)19-9-5-2-6-10-19/h1-10,17H,11-16H2 ZXKDQKMGPBQZPF-UHFFFAOYSA-N 50091903 1-Benzyl-4-(2-phenyl-oxazol-4-ylmethyl)-piperazine::CHEMBL62703 D(2) dopamine receptor Homo sapiens 27500 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091903&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12050194 103990123 CHEMBL62703 ZINC26172813 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012459 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Homo sapiens 120 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012461 COc1ccc(Br)cc1-c1nc(CNCC[C@@H]2CCN(Cc3ccccc3)C2)co1 InChI=1S/C24H28BrN3O2/c1-29-23-8-7-20(25)13-22(23)24-27-21(17-30-24)14-26-11-9-19-10-12-28(16-19)15-18-5-3-2-4-6-18/h2-8,13,17,19,26H,9-12,14-16H2,1H3/t19-/m1/s1 PUTIADDALKYHRM-LJQANCHMSA-N 50091904 CHEMBL65641::[2-((R)-1-Benzyl-pyrrolidin-3-yl)-ethyl]-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine D(2) dopamine receptor Homo sapiens 1070 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091904&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304621 103990124 CHEMBL65641 ZINC26176945 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012466 COc1ccc(Br)cc1-c1nc(CN[C@@H]2CCN(Cc3ccccc3)C2)co1 InChI=1S/C22H24BrN3O2/c1-27-21-8-7-17(23)11-20(21)22-25-19(15-28-22)12-24-18-9-10-26(14-18)13-16-5-3-2-4-6-16/h2-8,11,15,18,24H,9-10,12-14H2,1H3/t18-/m1/s1 NPLOIWFMUHLKNW-GOSISDBHSA-N 50091892 ((R)-1-Benzyl-pyrrolidin-3-yl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine::CHEMBL64752 D(2) dopamine receptor Homo sapiens 2450 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091892&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12050202 103990112 CHEMBL64752 ZINC26167966 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012468 C(NC1CCN(Cc2ccccc2)CC1)c1csc(n1)-c1ccccc1 InChI=1S/C22H25N3S/c1-3-7-18(8-4-1)16-25-13-11-20(12-14-25)23-15-21-17-26-22(24-21)19-9-5-2-6-10-19/h1-10,17,20,23H,11-16H2 LDOTVWGSWWUMAW-UHFFFAOYSA-N 50091899 (1-Benzyl-piperidin-4-yl)-(2-phenyl-thiazol-4-ylmethyl)-amine::CHEMBL302186 D(2) dopamine receptor Homo sapiens 23000 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091899&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12050200 103990119 CHEMBL302186 ZINC26167972 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012473 COc1ccc(Br)cc1-c1nc(CN2CCN(Cc3ccccc3)CC2)co1 InChI=1S/C22H24BrN3O2/c1-27-21-8-7-18(23)13-20(21)22-24-19(16-28-22)15-26-11-9-25(10-12-26)14-17-5-3-2-4-6-17/h2-8,13,16H,9-12,14-15H2,1H3 LFIRWQIMSRISSM-UHFFFAOYSA-N 50091907 1-Benzyl-4-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-piperazine::CHEMBL64696 D(2) dopamine receptor Homo sapiens 790 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12050195 103990127 CHEMBL64696 ZINC26168798 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012477 COc1ccc(Br)cc1-c1nc(CN2CCN(CC2)c2ccccc2)cs1 InChI=1S/C21H22BrN3OS/c1-26-20-8-7-16(22)13-19(20)21-23-17(15-27-21)14-24-9-11-25(12-10-24)18-5-3-2-4-6-18/h2-8,13,15H,9-12,14H2,1H3 IOPFZPQJWJQACY-UHFFFAOYSA-N 50091901 1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-4-phenyl-piperazine::CHEMBL64325 D(2) dopamine receptor Homo sapiens 610 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091901&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12050193 103990121 CHEMBL64325 ZINC16445932 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50012478 COc1ccc(Br)cc1-c1nc(CNC[C@@H]2CCN(Cc3ccccc3)C2)cs1 InChI=1S/C23H26BrN3OS/c1-28-22-8-7-19(24)11-21(22)23-26-20(16-29-23)13-25-12-18-9-10-27(15-18)14-17-5-3-2-4-6-17/h2-8,11,16,18,25H,9-10,12-15H2,1H3/t18-/m0/s1 FYSSSSIVDTYBFD-SFHVURJKSA-N 50091897 ((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-amine::CHEMBL64139 D(2) dopamine receptor Homo sapiens 420 ChEMBL 10.1016/s0960-894x(00)00405-4 10.7270/Q2FQ9X5Q 10987445 Einsiedel, J; Thomas, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091897&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304603 103990117 CHEMBL64139 ZINC26166264 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010315 C(N1CCC(CC1)n1cccc1)c1ccccc1 InChI=1S/C16H20N2/c1-2-6-15(7-3-1)14-17-12-8-16(9-13-17)18-10-4-5-11-18/h1-7,10-11,16H,8-9,12-14H2 UPRFZLANTXURKF-UHFFFAOYSA-N 50082169 1-Benzyl-4-pyrrol-1-yl-piperidine::CHEMBL326877 D(2) dopamine receptor Homo sapiens 8500 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search AXG 5RWO,5S9S,5Q1T 2779264 103982016 CHEMBL326877 ZINC00161500 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010317 C(N1CCC(CC1)n1ccc(c1)-c1cnco1)c1ccccc1 InChI=1S/C19H21N3O/c1-2-4-16(5-3-1)13-21-9-7-18(8-10-21)22-11-6-17(14-22)19-12-20-15-23-19/h1-6,11-12,14-15,18H,7-10,13H2 ASGPPKHUWWRTLM-UHFFFAOYSA-N 50082170 1-Benzyl-4-(3-oxazol-5-yl-pyrrol-1-yl)-piperidine::CHEMBL107529 D(2) dopamine receptor Homo sapiens 3200 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995378 103982017 CHEMBL107529 ZINC00008565 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010318 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010321 O=Cc1cccn1C1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-14-17-7-4-10-19(17)16-8-11-18(12-9-16)13-15-5-2-1-3-6-15/h1-7,10,14,16H,8-9,11-13H2 DYCKCLZHSRKOSL-UHFFFAOYSA-N 50082167 1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-2-carbaldehyde::CHEMBL109173 D(2) dopamine receptor Homo sapiens 1400 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082167&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3156990 103982014 CHEMBL109173 ZINC05736728 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010322 C[Si](C)(C)C#Cc1cccn1C1CCN(Cc2ccccc2)CC1 InChI=1S/C21H28N2Si/c1-24(2,3)17-13-20-10-7-14-23(20)21-11-15-22(16-12-21)18-19-8-5-4-6-9-19/h4-10,14,21H,11-12,15-16,18H2,1-3H3 KUZDNSHRAHWGBG-UHFFFAOYSA-N 50082168 1-Benzyl-4-(2-trimethylsilanylethynyl-pyrrol-1-yl)-piperidine::CHEMBL108160 D(2) dopamine receptor Homo sapiens 6200 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508239 103982015 CHEMBL108160 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010323 C(N1CCC(CC1)n1cccc1-c1cnco1)c1ccccc1 InChI=1S/C19H21N3O/c1-2-5-16(6-3-1)14-21-11-8-17(9-12-21)22-10-4-7-18(22)19-13-20-15-23-19/h1-7,10,13,15,17H,8-9,11-12,14H2 JTHXHSNJAJMWTQ-UHFFFAOYSA-N 50082166 1-Benzyl-4-(2-oxazol-5-yl-pyrrol-1-yl)-piperidine::CHEMBL104453 D(2) dopamine receptor Homo sapiens 610 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357869 103982013 CHEMBL104453 ZINC00024249 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010324 C#Cc1cccn1C1CCN(Cc2ccccc2)CC1 InChI=1S/C18H20N2/c1-2-17-9-6-12-20(17)18-10-13-19(14-11-18)15-16-7-4-3-5-8-16/h1,3-9,12,18H,10-11,13-15H2 CNGQSMFIQRDDKI-UHFFFAOYSA-N 50082164 1-Benzyl-4-(2-ethynyl-pyrrol-1-yl)-piperidine::CHEMBL325104 D(2) dopamine receptor Homo sapiens 6600 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082164&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508240 103982011 CHEMBL325104 ZINC26838608 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010316 O=Cc1ccn(c1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-14-16-6-11-19(13-16)17-7-9-18(10-8-17)12-15-4-2-1-3-5-15/h1-6,11,13-14,17H,7-10,12H2 NIMADOZRRAVFFL-UHFFFAOYSA-N 50082172 1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-3-carbaldehyde::CHEMBL422959 D(2) dopamine receptor Homo sapiens 49000 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508242 103982019 CHEMBL422959 ZINC26844541 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010326 C(N1CCC(CC1)n1cccc1C#Cc1ccccc1)c1ccccc1 InChI=1S/C24H24N2/c1-3-8-21(9-4-1)13-14-23-12-7-17-26(23)24-15-18-25(19-16-24)20-22-10-5-2-6-11-22/h1-12,17,24H,15-16,18-20H2 LGKGAIBCFWVOCC-UHFFFAOYSA-N 50082165 1-Benzyl-4-(2-phenylethynyl-pyrrol-1-yl)-piperidine::CHEMBL104092 D(2) dopamine receptor Homo sapiens 10000 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508238 103982012 CHEMBL104092 ZINC26836574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144110 N#CC(=Cc1cccn1C1CCN(Cc2ccccc2)CC1)C#N InChI=1S/C20H20N4/c21-14-18(15-22)13-20-7-4-10-24(20)19-8-11-23(12-9-19)16-17-5-2-1-3-6-17/h1-7,10,13,19H,8-9,11-12,16H2 WHTUEKIFAXDIRP-UHFFFAOYSA-N 50082163 2-[1-(1-Benzyl-piperidin-4-yl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL326864 D(2) dopamine receptor Homo sapiens 7800 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082163&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336552 103982010 CHEMBL326864 ZINC36216557 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010319 C#Cc1cccn1C1CCN(Cc2ccccc2)CC1 InChI=1S/C18H20N2/c1-2-17-9-6-12-20(17)18-10-13-19(14-11-18)15-16-7-4-3-5-8-16/h1,3-9,12,18H,10-11,13-15H2 CNGQSMFIQRDDKI-UHFFFAOYSA-N 50082164 1-Benzyl-4-(2-ethynyl-pyrrol-1-yl)-piperidine::CHEMBL325104 D(2) dopamine receptor Homo sapiens 6300 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082164&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508240 103982011 CHEMBL325104 ZINC26838608 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010320 C[Si](C)(C)C#Cc1cccn1C1CCN(Cc2ccccc2)CC1 InChI=1S/C21H28N2Si/c1-24(2,3)17-13-20-10-7-14-23(20)21-11-15-22(16-12-21)18-19-8-5-4-6-9-19/h4-10,14,21H,11-12,15-16,18H2,1-3H3 KUZDNSHRAHWGBG-UHFFFAOYSA-N 50082168 1-Benzyl-4-(2-trimethylsilanylethynyl-pyrrol-1-yl)-piperidine::CHEMBL108160 D(2) dopamine receptor Homo sapiens 4900 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508239 103982015 CHEMBL108160 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144132 Ic1cccn1C1CCN(Cc2ccccc2)CC1 InChI=1S/C16H19IN2/c17-16-7-4-10-19(16)15-8-11-18(12-9-15)13-14-5-2-1-3-6-14/h1-7,10,15H,8-9,11-13H2 LZMIVAWAFVXKJL-UHFFFAOYSA-N 50082171 1-Benzyl-4-(2-iodo-pyrrol-1-yl)-piperidine::CHEMBL106635 D(2) dopamine receptor Homo sapiens 5300 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508243 103982018 CHEMBL106635 ZINC20358060 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144133 N#CC(=Cc1ccn(c1)C1CCN(Cc2ccccc2)CC1)C#N InChI=1S/C20H20N4/c21-13-19(14-22)12-18-6-11-24(16-18)20-7-9-23(10-8-20)15-17-4-2-1-3-5-17/h1-6,11-12,16,20H,7-10,15H2 BUGYAANIQPCORQ-UHFFFAOYSA-N 50082173 2-[1-(1-Benzyl-piperidin-4-yl)-1H-pyrrol-3-ylmethylene]-malononitrile::CHEMBL104201 D(2) dopamine receptor Homo sapiens 13000 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336571 103982020 CHEMBL104201 ZINC36216550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144144 O=Cc1ccn(c1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-14-16-6-11-19(13-16)17-7-9-18(10-8-17)12-15-4-2-1-3-5-15/h1-6,11,13-14,17H,7-10,12H2 NIMADOZRRAVFFL-UHFFFAOYSA-N 50082172 1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-3-carbaldehyde::CHEMBL422959 D(2) dopamine receptor Homo sapiens 65000 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508242 103982019 CHEMBL422959 ZINC26844541 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50010325 C(N1CCC(CC1)n1cccc1)c1ccccc1 InChI=1S/C16H20N2/c1-2-6-15(7-3-1)14-17-12-8-16(9-13-17)18-10-4-5-11-18/h1-7,10-11,16H,8-9,12-14H2 UPRFZLANTXURKF-UHFFFAOYSA-N 50082169 1-Benzyl-4-pyrrol-1-yl-piperidine::CHEMBL326877 D(2) dopamine receptor Homo sapiens 9800 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search AXG 5RWO,5S9S,5Q1T 2779264 103982016 CHEMBL326877 ZINC00161500 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011443 CN(C)C1CCC2(C=C1)c1ccccc1C=Cc1ccc(Cl)cc21 InChI=1S/C22H22ClN/c1-24(2)19-11-13-22(14-12-19)20-6-4-3-5-16(20)7-8-17-9-10-18(23)15-21(17)22/h3-11,13,15,19H,12,14H2,1-2H3 FZXSXMYFIZKXPT-UHFFFAOYSA-N 50007550 3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro-5'H-dibenzo[a,d]cycloheptene)]-4-yl(dimethyl)amine::CHEMBL300647::Enantiomer 2'3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro-5'H-dibenzo[a,d]cycloheptene)]-4-yl(dimethyl)amine D(2) dopamine receptor Homo sapiens 6.5 ChEMBL 10.1021/jm00109a026 10.7270/Q2ZP4534 1674541 Froimowitz, M; Ramsby, S Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3038603 103920820 CHEMBL300647 ZINC13649957 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50011460 CN(C)C1CCC2(C=C1)c1ccccc1CCc1ccc(Cl)cc21 InChI=1S/C22H24ClN/c1-24(2)19-11-13-22(14-12-19)20-6-4-3-5-16(20)7-8-17-9-10-18(23)15-21(17)22/h3-6,9-11,13,15,19H,7-8,12,14H2,1-2H3 QPNVVIACYJVUOX-UHFFFAOYSA-N 50007551 3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro-5'H-dibenzo[a,d]cycloheptene)]-4-yl(dimethyl)amine::CHEMBL45491::Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro-5'H-dibenzo[a,d]cycloheptene)]-4-yl(dimethyl)amine D(2) dopamine receptor Homo sapiens 2.0 ChEMBL 10.1021/jm00109a026 10.7270/Q2ZP4534 1674541 Froimowitz, M; Ramsby, S Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3039881 103920821 CHEMBL45491 ZINC13649953 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50014909 C([C@H]1CNC(=N1)c1ccccc1)N1CCN(CC1)c1ccccc1 InChI=1S/C20H24N4/c1-3-7-17(8-4-1)20-21-15-18(22-20)16-23-11-13-24(14-12-23)19-9-5-2-6-10-19/h1-10,18H,11-16H2,(H,21,22)/t18-/m1/s1 QRYAMGGRUIKACE-GOSISDBHSA-N 50104341 1-Phenyl-4-((R)-2-phenyl-4,5-dihydro-1H-imidazol-4-ylmethyl)-piperazine; hydrochloride::CHEMBL540039 D(2) dopamine receptor Homo sapiens 10000 ChEMBL 10.1016/s0960-894x(01)00484-x 10.7270/Q27P8ZWZ 11549463 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247720 104000280 CHEMBL540039 ZINC22451171 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50014912 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 52 ChEMBL 10.1016/s0960-894x(01)00484-x 10.7270/Q27P8ZWZ 11549463 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50014924 COc1ccc(Br)cc1C1=N[C@@H](CN2CCN(CC2)c2ccccc2)CO1 InChI=1S/C21H24BrN3O2/c1-26-20-8-7-16(22)13-19(20)21-23-17(15-27-21)14-24-9-11-25(12-10-24)18-5-3-2-4-6-18/h2-8,13,17H,9-12,14-15H2,1H3/t17-/m0/s1 LKDKZDZBTSCLCY-KRWDZBQOSA-N 50104342 1-[(S)-2-(5-Bromo-2-methoxy-phenyl)-4,5-dihydro-oxazol-4-ylmethyl]-4-phenyl-piperazine::CHEMBL313320 D(2) dopamine receptor Homo sapiens 2200 ChEMBL 10.1016/s0960-894x(01)00484-x 10.7270/Q27P8ZWZ 11549463 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319368 104000281 CHEMBL313320 ZINC26572361 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50014931 C[C@@H]1OC(=N[C@H]1CN1CCN(CC1)c1ccccc1)c1ccccc1 InChI=1S/C21H25N3O/c1-17-20(22-21(25-17)18-8-4-2-5-9-18)16-23-12-14-24(15-13-23)19-10-6-3-7-11-19/h2-11,17,20H,12-16H2,1H3/t17-,20-/m0/s1 JNZNIWXTQKSJBP-PXNSSMCTSA-N 50104345 1-((4S,5S)-5-Methyl-2-phenyl-4,5-dihydro-oxazol-4-ylmethyl)-4-phenyl-piperazine::CHEMBL83306 D(2) dopamine receptor Homo sapiens 820 ChEMBL 10.1016/s0960-894x(01)00484-x 10.7270/Q27P8ZWZ 11549463 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319369 104000284 CHEMBL83306 ZINC26572363 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50014940 C([C@H]1COC(=N1)c1ccccc1)N1CCN(CC1)c1ccccc1 InChI=1S/C20H23N3O/c1-3-7-17(8-4-1)20-21-18(16-24-20)15-22-11-13-23(14-12-22)19-9-5-2-6-10-19/h1-10,18H,11-16H2/t18-/m0/s1 JFMAZBIWGGSVJX-SFHVURJKSA-N 50104343 1-Phenyl-4-((S)-2-phenyl-4,5-dihydro-oxazol-4-ylmethyl)-piperazine::CHEMBL86060 D(2) dopamine receptor Homo sapiens 330 ChEMBL 10.1016/s0960-894x(01)00484-x 10.7270/Q27P8ZWZ 11549463 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319102 104000282 CHEMBL86060 ZINC26567049 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50014941 COc1ccc(Br)cc1C1=N[C@@H](CN2CCN(CC2)c2ccccc2)[C@@H](C)O1 InChI=1S/C22H26BrN3O2/c1-16-20(24-22(28-16)19-14-17(23)8-9-21(19)27-2)15-25-10-12-26(13-11-25)18-6-4-3-5-7-18/h3-9,14,16,20H,10-13,15H2,1-2H3/t16-,20+/m1/s1 XHTCEJWQQIHAOR-UZLBHIALSA-N 50104344 1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4,5-dihydro-oxazol-4-ylmethyl]-4-phenyl-piperazine::CHEMBL315564 D(2) dopamine receptor Homo sapiens 2400 ChEMBL 10.1016/s0960-894x(01)00484-x 10.7270/Q27P8ZWZ 11549463 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319370 104000283 CHEMBL315564 ZINC26571053 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50014946 C([C@H]1CSC(=N1)c1ccccc1)N1CCN(CC1)c1ccccc1 InChI=1S/C20H23N3S/c1-3-7-17(8-4-1)20-21-18(16-24-20)15-22-11-13-23(14-12-22)19-9-5-2-6-10-19/h1-10,18H,11-16H2/t18-/m0/s1 GZMWGZHXHSTIMC-SFHVURJKSA-N 50104346 1-Phenyl-4-((S)-2-phenyl-4,5-dihydro-thiazol-4-ylmethyl)-piperazine::CHEMBL82527 D(2) dopamine receptor Homo sapiens 1100 ChEMBL 10.1016/s0960-894x(01)00484-x 10.7270/Q27P8ZWZ 11549463 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319361 104000285 CHEMBL82527 ZINC26504623 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018256 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O/c1-17-14-19-4-2-3-5-21(19)26(17)22(27)16-25-12-10-24(11-13-25)15-18-6-8-20(23)9-7-18/h2-9,17H,10-16H2,1H3 JIFUZIJTCAAWNY-UHFFFAOYSA-N 50119911 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106916 D(2) dopamine receptor Homo sapiens 209 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119911&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952003 104013038 CHEMBL106916 ZINC22941263 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50586286 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O/c1-17-14-19-4-2-3-5-21(19)26(17)22(27)16-25-12-10-24(11-13-25)15-18-6-8-20(23)9-7-18/h2-9,17H,10-16H2,1H3 JIFUZIJTCAAWNY-UHFFFAOYSA-N 50119911 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106916 D(2) dopamine receptor Homo sapiens 9 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119911&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952003 104013038 CHEMBL106916 ZINC22941263 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50586308 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 InChI=1S/C23H29N3O/c1-18-7-9-20(10-8-18)16-24-11-13-25(14-12-24)17-23(27)26-19(2)15-21-5-3-4-6-22(21)26/h3-10,19H,11-17H2,1-2H3 BKDQVRCFIJMWOR-UHFFFAOYSA-N 50119892 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107742 D(2) dopamine receptor Homo sapiens 140 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119892&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9799123 104013019 CHEMBL107742 ZINC22941419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50016818 N#Cc1cc(CN2CCN(CC2)c2ccccc2)c[nH]1 InChI=1S/C16H18N4/c17-11-15-10-14(12-18-15)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2 APOXKSCRLNZDPC-UHFFFAOYSA-N 50403915 CHEMBL2113718 D(2) dopamine receptor Homo sapiens 3400 ChEMBL 10.1016/s0960-894x(02)00316-5 10.7270/Q2T72J0V 12113813 Bergauer, M; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403915&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71458071 163352939 CHEMBL2113718 ZINC13443859 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50016824 C#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 InChI=1S/C17H19N3/c1-2-15-12-16(18-13-15)14-19-8-10-20(11-9-19)17-6-4-3-5-7-17/h1,3-7,12-13,18H,8-11,14H2 VOPNYIHLMCVSPL-UHFFFAOYSA-N 50115717 1-(4-Ethynyl-1H-pyrrol-2-ylmethyl)-4-phenyl-piperazine::CHEMBL57176 D(2) dopamine receptor Homo sapiens 580 ChEMBL 10.1016/s0960-894x(02)00316-5 10.7270/Q2T72J0V 12113813 Bergauer, M; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115717&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378194 104009565 CHEMBL57176 ZINC13443850 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50016825 C(N1CCN(CC1)c1ccccc1)c1cc(c[nH]1)-c1ccccc1 InChI=1S/C21H23N3/c1-3-7-18(8-4-1)19-15-20(22-16-19)17-23-11-13-24(14-12-23)21-9-5-2-6-10-21/h1-10,15-16,22H,11-14,17H2 YLPJQEDKFKCTSE-UHFFFAOYSA-N 50115716 1-Phenyl-4-(4-phenyl-1H-pyrrol-2-ylmethyl)-piperazine::1-phenyl-4-((4-phenyl-1H-pyrrol-2-yl)methyl)piperazine::CHEMBL60815 D(2) dopamine receptor Homo sapiens 230 ChEMBL 10.1016/s0960-894x(02)00316-5 10.7270/Q2T72J0V 12113813 Bergauer, M; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300865 104009564 CHEMBL60815 ZINC13443844 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50016829 C(N1CCN(CC1)c1ccccc1)c1ccc[nH]1 InChI=1S/C15H19N3/c1-2-6-15(7-3-1)18-11-9-17(10-12-18)13-14-5-4-8-16-14/h1-8,16H,9-13H2 DCDSVYQQSBWIRG-UHFFFAOYSA-N 50115719 1-Phenyl-4-(1H-pyrrol-2-ylmethyl)-piperazine::CHEMBL294394 D(2) dopamine receptor Homo sapiens 3100 ChEMBL 10.1016/s0960-894x(02)00316-5 10.7270/Q2T72J0V 12113813 Bergauer, M; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115719&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12997400 104009567 CHEMBL294394 ZINC13443853 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50016832 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 28.0 ChEMBL 10.1016/s0960-894x(02)00316-5 10.7270/Q2T72J0V 12113813 Bergauer, M; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50017020 CCCN1CCc2nn3ccccc3c2C1 InChI=1S/C13H17N3/c1-2-7-15-9-6-12-11(10-15)13-5-3-4-8-16(13)14-12/h3-5,8H,2,6-7,9-10H2,1H3 URWBDIMBZFWGSF-UHFFFAOYSA-N 50116765 3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene::CHEMBL80845 D(2) dopamine receptor Homo sapiens 130 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316315 104010404 CHEMBL80845 ZINC12355903 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021728 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19-/m0/s1 DCJWAUUNGWWIFD-LIRRHRJNSA-N 50132703 CHEMBL111749::N-((3R,4S)-1-Benzyl-4-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 15.0 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132703&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44340097 104023680 CHEMBL111749 ZINC13553232 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021730 COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C InChI=1S/C24H25BrN2O2/c1-16-13-27(14-17-8-4-3-5-9-17)15-22(16)26-24(28)20-12-21(25)18-10-6-7-11-19(18)23(20)29-2/h3-12,16,22H,13-15H2,1-2H3,(H,26,28)/t16-,22-/m0/s1 ZLQMLDGHTKCIRQ-AOMKIAJQSA-N 50132691 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((3R,4S)-1-benzyl-4-methyl-pyrrolidin-3-yl)-amide::CHEMBL430522 D(2) dopamine receptor Homo sapiens 1000 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132691&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44339984 104023668 CHEMBL430522 ZINC13553234 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021768 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021782 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1 DCJWAUUNGWWIFD-KUHUBIRLSA-N 50132696 CHEMBL326454::N-((3R,4R)-1-Benzyl-4-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 3.00 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132696&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977532 104023673 CHEMBL326454 ZINC13553236 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021787 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCCN(Cc2ccccc2)C1 InChI=1S/C21H26ClN3O2/c1-23-19-12-20(27-2)17(11-18(19)22)21(26)24-16-9-6-10-25(14-16)13-15-7-4-3-5-8-15/h3-5,7-8,11-12,16,23H,6,9-10,13-14H2,1-2H3,(H,24,26)/t16-/m0/s1 LGRVHISBHOARSB-INIZCTEOSA-N 50132702 CHEMBL447476::N-((S)-1-Benzyl-piperidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 130 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132702&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44339879 104023679 CHEMBL447476 ZINC13553255 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021801 COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1 XNUNIHJOMFCFRQ-LIRRHRJNSA-N 50132700 4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::CHEMBL322802 D(2) dopamine receptor Homo sapiens 8.6 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132700&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44339953 104023677 CHEMBL322802 ZINC13553228 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021804 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C InChI=1S/C22H28ClN3O2/c1-15-13-26(14-16-7-5-4-6-8-16)10-9-19(15)25-22(27)17-11-18(23)20(24-2)12-21(17)28-3/h4-8,11-12,15,19,24H,9-10,13-14H2,1-3H3,(H,25,27)/t15-,19-/m0/s1 OJELFRWBMVFUDD-KXBFYZLASA-N 50132695 CHEMBL109912::N-((3S,4S)-1-Benzyl-3-methyl-piperidin-4-yl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Homo sapiens 39.0 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132695&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44340084 104023672 CHEMBL109912 ZINC13553230 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021813 COc1c(cc(I)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C23H23IN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)13-20(22)23(27)25-17-11-12-26(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,25,27)/t17-/m1/s1 MNUMQOWSJLDQOS-QGZVFWFLSA-N 50132689 4-Iodo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide::CHEMBL325772 D(2) dopamine receptor Homo sapiens 70.0 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132689&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44340227 104023666 CHEMBL325772 ZINC13553242 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021815 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C24H25BrN2O2/c1-29-23-20-10-6-5-9-19(20)22(25)13-21(23)24(28)26-14-18-11-12-27(16-18)15-17-7-3-2-4-8-17/h2-10,13,18H,11-12,14-16H2,1H3,(H,26,28)/t18-/m0/s1 CNAWUGXPLJMOSN-SFHVURJKSA-N 50132698 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((S)-1-benzyl-pyrrolidin-3-ylmethyl)-amide::CHEMBL325818 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44340376 104023675 CHEMBL325818 ZINC13553248 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021823 COc1c(cc(Br)c2ccccc12)C(=O)NCC[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C25H27BrN2O2/c1-30-24-21-10-6-5-9-20(21)23(26)15-22(24)25(29)27-13-11-19-12-14-28(17-19)16-18-7-3-2-4-8-18/h2-10,15,19H,11-14,16-17H2,1H3,(H,27,29)/t19-/m1/s1 RJZYRNTXYJEPMD-LJQANCHMSA-N 50132690 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-((R)-1-benzyl-pyrrolidin-3-yl)-ethyl]-amide::CHEMBL113471 D(2) dopamine receptor Homo sapiens 2800 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132690&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44340302 104023667 CHEMBL113471 ZINC13553250 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021829 COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C InChI=1S/C24H25BrN2O2/c1-16-13-27(14-17-8-4-3-5-9-17)15-22(16)26-24(28)20-12-21(25)18-10-6-7-11-19(18)23(20)29-2/h3-12,16,22H,13-15H2,1-2H3,(H,26,28)/t16-,22+/m1/s1 ZLQMLDGHTKCIRQ-ZHRRBRCNSA-N 50132692 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((3R,4R)-1-benzyl-4-methyl-pyrrolidin-3-yl)-amide::CHEMBL321492 D(2) dopamine receptor Homo sapiens 290 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44339992 104023669 CHEMBL321492 ZINC13553238 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50021830 COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C23H23BrN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)13-20(22)23(27)25-17-11-12-26(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,25,27)/t17-/m1/s1 UBVYCNOXGQYSRQ-QGZVFWFLSA-N 50099814 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide::4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-3-yl)-amide::CHEMBL298875 D(2) dopamine receptor Homo sapiens 150 ChEMBL 10.1016/s0960-894x(03)00678-4 10.7270/Q2639P5F 12951112 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551026 103996639 CHEMBL298875 ZINC13553240 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018870 Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccc(F)cc1 InChI=1S/C25H24ClFN4/c1-18-23(17-29-13-15-30(16-14-29)22-11-7-20(26)8-12-22)25-4-2-3-24(31(25)28-18)19-5-9-21(27)10-6-19/h2-12H,13-17H2,1H3 NSRMSZBPAQTJBS-UHFFFAOYSA-N 50109948 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-fluoro-phenyl)-2-methyl-pyrazolo[1,5-a]pyridine::CHEMBL160749 D(2) dopamine receptor Homo sapiens 14000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372154 104004836 CHEMBL160749 ZINC13438665 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018872 Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C25H25ClN4/c1-19-23(18-28-14-16-29(17-15-28)22-12-10-21(26)11-13-22)25-9-5-8-24(30(25)27-19)20-6-3-2-4-7-20/h2-13H,14-18H2,1H3 JQBYEGVGELAAOI-UHFFFAOYSA-N 50109946 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-7-phenyl-pyrazolo[1,5-a]pyridine::CHEMBL351550 D(2) dopamine receptor Homo sapiens 28000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372153 104004834 CHEMBL351550 ZINC13438659 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018875 Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)N2CCN(Cc3ccccc3)CC2)CC1 InChI=1S/C29H33ClN6/c30-26-9-11-27(12-10-26)34-17-13-33(14-18-34)23-25-21-31-36-28(25)7-4-8-29(36)35-19-15-32(16-20-35)22-24-5-2-1-3-6-24/h1-12,21H,13-20,22-23H2 GYWHDZIJHYATFG-UHFFFAOYSA-N 50109949 7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL160266 D(2) dopamine receptor Homo sapiens 640 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371996 104004837 CHEMBL160266 ZINC13438668 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018881 Clc1ccc(cc1)N1CCN(Cc2cnn3c(C=O)cccc23)CC1 InChI=1S/C19H19ClN4O/c20-16-4-6-17(7-5-16)23-10-8-22(9-11-23)13-15-12-21-24-18(14-25)2-1-3-19(15)24/h1-7,12,14H,8-11,13H2 JQJZAUBSLUYDAA-UHFFFAOYSA-N 50109950 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-7-carbaldehyde::CHEMBL346805 D(2) dopamine receptor Homo sapiens 9500 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371932 104004838 CHEMBL346805 ZINC13438680 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018884 Cc1cccn2ncc(CN3CCN(CC3)c3ccc(Cl)cc3)c12 InChI=1S/C19H21ClN4/c1-15-3-2-8-24-19(15)16(13-21-24)14-22-9-11-23(12-10-22)18-6-4-17(20)5-7-18/h2-8,13H,9-12,14H2,1H3 FVQOIDZBAPLYGQ-UHFFFAOYSA-N 50109953 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4-methyl-pyrazolo[1,5-a]pyridine::4-(4-Chloro-phenyl)-1-(4-methyl-pyrazolo[1,5-a]pyridin-3-ylmethyl)-piperazin-1-ium::CHEMBL156369 D(2) dopamine receptor Homo sapiens 12000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44270444 104004841 CHEMBL156369 ZINC13438689 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018885 Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)-c2ccccc2)CC1 InChI=1S/C24H23ClN4/c25-21-9-11-22(12-10-21)28-15-13-27(14-16-28)18-20-17-26-29-23(7-4-8-24(20)29)19-5-2-1-3-6-19/h1-12,17H,13-16,18H2 XDYCBVKXSXIDCW-UHFFFAOYSA-N 50109942 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phenyl-pyrazolo[1,5-a]pyridine::CHEMBL155913 D(2) dopamine receptor Homo sapiens 5400 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372009 104004830 CHEMBL155913 ZINC13438656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018886 OCc1cccn2ncc(CN3CCN(CC3)c3ccc(Cl)cc3)c12 InChI=1S/C19H21ClN4O/c20-17-3-5-18(6-4-17)23-10-8-22(9-11-23)13-16-12-21-24-7-1-2-15(14-25)19(16)24/h1-7,12,25H,8-11,13-14H2 AYTNWERJAAXIPL-UHFFFAOYSA-N 50109951 CHEMBL160396::{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridin-4-yl}-methanol D(2) dopamine receptor Homo sapiens 79000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372312 104004839 CHEMBL160396 ZINC13438683 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50032356 Oc1cc2[C@@H](CNCc2cc1Cl)c1ccccc1 InChI=1S/C15H14ClNO/c16-14-6-11-8-17-9-13(12(11)7-15(14)18)10-4-2-1-3-5-10/h1-7,13,17-18H,8-9H2/t13-/m0/s1 MGAQDUSMABIJCH-ZDUSSCGKSA-N 50228323 CHEMBL59603 D(2) dopamine receptor Homo sapiens 1820 ChEMBL 10.1021/jm00129a006 10.7270/Q2RV0QXV 2527994 Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50228323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50228323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198594 378167844 CHEMBL59603 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50032357 CCCN1CCc2cc(Cl)c(O)cc2[C@@H]1c1ccccc1 InChI=1S/C18H20ClNO/c1-2-9-20-10-8-14-11-16(19)17(21)12-15(14)18(20)13-6-4-3-5-7-13/h3-7,11-12,18,21H,2,8-10H2,1H3/t18-/m0/s1 UCVFZVSEYSSSHP-SFHVURJKSA-N 50367601 CHEMBL293828 D(2) dopamine receptor Homo sapiens 1905 ChEMBL 10.1021/jm00129a006 10.7270/Q2RV0QXV 2527994 Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198601 160846703 CHEMBL293828 ZINC13675924 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50032360 CN1CCc2cc(Cl)c(O)cc2[C@@H]1c1ccccc1 InChI=1S/C16H16ClNO/c1-18-8-7-12-9-14(17)15(19)10-13(12)16(18)11-5-3-2-4-6-11/h2-6,9-10,16,19H,7-8H2,1H3/t16-/m0/s1 AVXGCGYACIYZAR-INIZCTEOSA-N 50038349 (S)-6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::CHEMBL303993 D(2) dopamine receptor Homo sapiens 1862 ChEMBL 10.1021/jm00129a006 10.7270/Q2RV0QXV 2527994 Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10107367 103945768 CHEMBL303993 ZINC13675794 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50032362 CN1C[C@@H](c2ccccc2)c2cc(O)c(Cl)cc2C1 InChI=1S/C16H16ClNO/c1-18-9-12-7-15(17)16(19)8-13(12)14(10-18)11-5-3-2-4-6-11/h2-8,14,19H,9-10H2,1H3/t14-/m0/s1 QMEAXKMTOSHGKG-AWEZNQCLSA-N 50228321 CHEMBL302393 D(2) dopamine receptor Homo sapiens 263 ChEMBL 10.1021/jm00129a006 10.7270/Q2RV0QXV 2527994 Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50228321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50228321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198597 378167842 CHEMBL302393 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50032363 CN1CCc2cc(Cl)c(O)cc2[C@@H]1Cc1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-10-15(18)17(20)11-14(13)16(19)9-12-5-3-2-4-6-12/h2-6,10-11,16,20H,7-9H2,1H3/t16-/m0/s1 JHDHNKDQVCVUJN-INIZCTEOSA-N 50228322 CHEMBL64117 D(2) dopamine receptor Homo sapiens 145 ChEMBL 10.1021/jm00129a006 10.7270/Q2RV0QXV 2527994 Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50228322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50228322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198587 378167843 CHEMBL64117 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50032364 CN1CCc2cc(Cl)c(O)cc2[C@H]1c1ccccc1 InChI=1S/C16H16ClNO/c1-18-8-7-12-9-14(17)15(19)10-13(12)16(18)11-5-3-2-4-6-11/h2-6,9-10,16,19H,7-8H2,1H3/t16-/m1/s1 AVXGCGYACIYZAR-MRXNPFEDSA-N 50038350 (R)-6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::CHEMBL293158 D(2) dopamine receptor Homo sapiens 19055 ChEMBL 10.1021/jm00129a006 10.7270/Q2RV0QXV 2527994 Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198585 103945769 CHEMBL293158 ZINC13675796 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50024008 CN1CCc2cc(Br)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H16BrNO2/c1-19-5-4-10-6-11(18)8-12-15(10)13(19)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,20-21H,4-5,7H2,1H3/t13-/m1/s1 SETZXJXEHHDPBP-CYBMUJFWSA-N 50010696 (R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL276326 D(2) dopamine receptor Homo sapiens 728 ChEMBL 10.1021/jm00126a009 10.7270/Q2Q23Z7P 2524592 Ramsby, S; Neumeyer, JL; Grigoriadis, D; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010696&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15627832 103923442 CHEMBL276326 ZINC28220764 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50024009 CN1CCc2cc(F)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H16FNO2/c1-19-5-4-10-6-11(18)8-12-15(10)13(19)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,20-21H,4-5,7H2,1H3/t13-/m1/s1 YBEUIAYJOLGULC-CYBMUJFWSA-N 50016786 (R)-2-Fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL18598 D(2) dopamine receptor Homo sapiens 0.430000 ChEMBL 10.1021/jm00126a009 10.7270/Q2Q23Z7P 2524592 Ramsby, S; Neumeyer, JL; Grigoriadis, D; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128965 103928154 CHEMBL18598 ZINC28220760 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50024010 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 0.660000 ChEMBL 10.1021/jm00126a009 10.7270/Q2Q23Z7P 2524592 Ramsby, S; Neumeyer, JL; Grigoriadis, D; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50024012 CN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO3/c1-18-5-4-10-6-11(19)8-12-15(10)13(18)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,19-21H,4-5,7H2,1H3/t13-/m1/s1 QNBCPLWFVGLFHO-CYBMUJFWSA-N 50010698 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::CHEMBL19130 D(2) dopamine receptor Homo sapiens 1.1 ChEMBL 10.1021/jm00126a009 10.7270/Q2Q23Z7P 2524592 Ramsby, S; Neumeyer, JL; Grigoriadis, D; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603797 103923444 CHEMBL19130 ZINC01561184 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50024013 CN1CCc2cc(N)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H18N2O2/c1-19-5-4-10-6-11(18)8-12-15(10)13(19)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,20-21H,4-5,7,18H2,1H3/t13-/m1/s1 MJZQRNCUULBFRH-CYBMUJFWSA-N 50016785 (R)-2-Amino-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Amino-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL276042 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1021/jm00126a009 10.7270/Q2Q23Z7P 2524592 Ramsby, S; Neumeyer, JL; Grigoriadis, D; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15627829 103928153 CHEMBL276042 ZINC05851200 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50032349 Oc1cc2[C@@H](NCCc2cc1Cl)c1ccccc1 InChI=1S/C15H14ClNO/c16-13-8-11-6-7-17-15(12(11)9-14(13)18)10-4-2-1-3-5-10/h1-5,8-9,15,17-18H,6-7H2/t15-/m0/s1 VXQGSKLYCJFAKI-HNNXBMFYSA-N 50367602 CHEMBL65397 D(2) dopamine receptor Homo sapiens 3715 ChEMBL 10.1021/jm00129a006 10.7270/Q2RV0QXV 2527994 Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198590 160846704 CHEMBL65397 ZINC13739904 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50032351 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Homo sapiens 891 ChEMBL 10.1021/jm00129a006 10.7270/Q2RV0QXV 2527994 Charifson, PS; Bowen, JP; Wyrick, SD; Hoffman, AJ; Cory, M; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50025621 COC(=O)c1ccc(Cc2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1 InChI=1S/C23H19ClN2O2/c1-28-23(27)18-10-6-16(7-11-18)14-22-25-20-4-2-3-5-21(20)26(22)15-17-8-12-19(24)13-9-17/h2-13H,14-15H2,1H3 KJIJBYGPXHPNJY-UHFFFAOYSA-N 50147385 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylmethyl]-benzoic acid methyl ester::CHEMBL320734 D(2) dopamine receptor Homo sapiens >12000 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147385&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338297 104035877 CHEMBL320734 ZINC26955167 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50025622 COC(=O)c1ccc(CS(=O)c2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1 InChI=1S/C23H19ClN2O3S/c1-29-22(27)18-10-6-17(7-11-18)15-30(28)23-25-20-4-2-3-5-21(20)26(23)14-16-8-12-19(24)13-9-16/h2-13H,14-15H2,1H3 YJNUYVIFARPTCL-UHFFFAOYSA-N 50147376 4-[1-(4-Chloro-benzyl)-1H-benzoimidazole-2-sulfinylmethyl]-benzoic acid methyl ester::CHEMBL108242 D(2) dopamine receptor Homo sapiens 1500 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338291 104035868 CHEMBL108242 ZINC26957431 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50025625 COC(=O)c1ccc(cc1)-c1nc2ccccc2n1Cc1ccc(Cl)cc1 InChI=1S/C22H17ClN2O2/c1-27-22(26)17-10-8-16(9-11-17)21-24-19-4-2-3-5-20(19)25(21)14-15-6-12-18(23)13-7-15/h2-13H,14H2,1H3 GLYQQBFMZKSXNY-UHFFFAOYSA-N 50147374 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-yl]-benzoic acid methyl ester::CHEMBL108243 D(2) dopamine receptor Homo sapiens 800 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338292 104035866 CHEMBL108243 ZINC26957437 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50025627 COC(=O)c1ccc(CSc2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1 InChI=1S/C23H19ClN2O2S/c1-28-22(27)18-10-6-17(7-11-18)15-29-23-25-20-4-2-3-5-21(20)26(23)14-16-8-12-19(24)13-9-16/h2-13H,14-15H2,1H3 DMAAYDZJXUUROB-UHFFFAOYSA-N 50147382 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylsulfanylmethyl]-benzoic acid methyl ester::CHEMBL324619 D(2) dopamine receptor Homo sapiens 297 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338387 104035874 CHEMBL324619 ZINC26945880 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50270646 COC(=O)c1ccc(\C=C\c2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1 InChI=1S/C24H19ClN2O2/c1-29-24(28)19-11-6-17(7-12-19)10-15-23-26-21-4-2-3-5-22(21)27(23)16-18-8-13-20(25)14-9-18/h2-15H,16H2,1H3/b15-10+ XBIIFHQGMIKLAD-XNTDXEJSSA-N 50147371 4-{(E)-2-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-yl]-vinyl}-benzoic acid methyl ester::CHEMBL111054 D(2) dopamine receptor Homo sapiens 67 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147371&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338310 104035863 CHEMBL111054 ZINC26966311 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50270682 COC(=O)c1ccc(CCc2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1 InChI=1S/C24H21ClN2O2/c1-29-24(28)19-11-6-17(7-12-19)10-15-23-26-21-4-2-3-5-22(21)27(23)16-18-8-13-20(25)14-9-18/h2-9,11-14H,10,15-16H2,1H3 AFECYHQHVIVPNI-UHFFFAOYSA-N 50147379 4-{2-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-yl]-ethyl}-benzoic acid methyl ester::CHEMBL108289 D(2) dopamine receptor Homo sapiens 137 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338326 104035871 CHEMBL108289 ZINC26953902 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50270683 COC(=O)c1ccc(Nc2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1 InChI=1S/C22H18ClN3O2/c1-28-21(27)16-8-12-18(13-9-16)24-22-25-19-4-2-3-5-20(19)26(22)14-15-6-10-17(23)11-7-15/h2-13H,14H2,1H3,(H,24,25) BIRXIMHINOMMAU-UHFFFAOYSA-N 50147381 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylamino]-benzoic acid methyl ester::CHEMBL110063 D(2) dopamine receptor Homo sapiens 5400 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338308 104035873 CHEMBL110063 ZINC26965238 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50023406 Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H28FN3OS/c25-16-7-8-18(20(26)14-16)22(29)5-2-10-27-12-9-21-19(15-27)17-4-1-6-23-24(17)28(21)11-3-13-30-23/h1,4,6-8,14,19,21H,2-3,5,9-13,15,26H2/t19-,21-/m0/s1 DPASSLWFBPICMV-FPOVZHCZSA-N 50125173 1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL166310 D(2) dopamine receptor Homo sapiens 2.7 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378077 104017407 CHEMBL166310 ZINC13487998 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50025623 COC(=O)c1ccc(CSc2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1 InChI=1S/C23H19ClN2O2S/c1-28-22(27)18-10-6-17(7-11-18)15-29-23-25-20-4-2-3-5-21(20)26(23)14-16-8-12-19(24)13-9-16/h2-13H,14-15H2,1H3 DMAAYDZJXUUROB-UHFFFAOYSA-N 50147382 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylsulfanylmethyl]-benzoic acid methyl ester::CHEMBL324619 D(2) dopamine receptor Homo sapiens 73 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338387 104035874 CHEMBL324619 ZINC26945880 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50025624 COC(=O)c1ccc(cc1)-c1nc2ccccc2n1Cc1ccc(Cl)cc1 InChI=1S/C22H17ClN2O2/c1-27-22(26)17-10-8-16(9-11-17)21-24-19-4-2-3-5-20(19)25(21)14-15-6-12-18(23)13-7-15/h2-13H,14H2,1H3 GLYQQBFMZKSXNY-UHFFFAOYSA-N 50147374 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-yl]-benzoic acid methyl ester::CHEMBL108243 D(2) dopamine receptor Homo sapiens 8000 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338292 104035866 CHEMBL108243 ZINC26957437 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50025626 COC(=O)c1ccc(Nc2nc3ccccc3n2Cc2ccc(Cl)cc2)cc1 InChI=1S/C22H18ClN3O2/c1-28-21(27)16-8-12-18(13-9-16)24-22-25-19-4-2-3-5-20(19)26(22)14-15-6-10-17(23)11-7-15/h2-13H,14H2,1H3,(H,24,25) BIRXIMHINOMMAU-UHFFFAOYSA-N 50147381 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-ylamino]-benzoic acid methyl ester::CHEMBL110063 D(2) dopamine receptor Homo sapiens 5400 ChEMBL 10.1016/j.bmcl.2004.04.005 10.7270/Q2DB8198 15149674 Beaulieu, C; Wang, Z; Denis, D; Greig, G; Lamontagne, S; O'Neill, G; Slipetz, D; Wang, J Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338308 104035873 CHEMBL110063 ZINC26965238 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50023514 O=C1C[C@@H](CN2CCN(CC2)c2ccccc2)NC(=N1)c1ccccc1 InChI=1S/C21H24N4O/c26-20-15-18(22-21(23-20)17-7-3-1-4-8-17)16-24-11-13-25(14-12-24)19-9-5-2-6-10-19/h1-10,18H,11-16H2,(H,22,23,26)/t18-/m0/s1 DKXYPAWNMBQJBN-SFHVURJKSA-N 50124196 (S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6-dihydro-3H-pyrimidin-4-one::CHEMBL168541 D(2) dopamine receptor Homo sapiens 6400 ChEMBL 10.1016/s0960-894x(03)00004-0 10.7270/Q26T0N5V 12617906 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124196&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381276 104016553 CHEMBL168541 ZINC22927172 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50023516 C([C@@H]1CCNC(=N1)c1ccccc1)N1CCN(CC1)c1ccccc1 InChI=1S/C21H26N4/c1-3-7-18(8-4-1)21-22-12-11-19(23-21)17-24-13-15-25(16-14-24)20-9-5-2-6-10-20/h1-10,19H,11-17H2,(H,22,23)/t19-/m0/s1 BJWYIHWMKMZYRS-IBGZPJMESA-N 50124193 (S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine::CHEMBL169459 D(2) dopamine receptor Homo sapiens 30000 ChEMBL 10.1016/s0960-894x(03)00004-0 10.7270/Q26T0N5V 12617906 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124193&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10359539 104016550 CHEMBL169459 ZINC19359217 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50023517 COc1ccc(Br)cc1C1=N[C@@H](CN2CCN(CC2)c2ccccc2)CCN1 InChI=1S/C22H27BrN4O/c1-28-21-8-7-17(23)15-20(21)22-24-10-9-18(25-22)16-26-11-13-27(14-12-26)19-5-3-2-4-6-19/h2-8,15,18H,9-14,16H2,1H3,(H,24,25)/t18-/m1/s1 RVBVZFLMCDGFOZ-GOSISDBHSA-N 50124192 (R)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine::CHEMBL169889 D(2) dopamine receptor Homo sapiens 44000 ChEMBL 10.1016/s0960-894x(03)00004-0 10.7270/Q26T0N5V 12617906 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381217 104016549 CHEMBL169889 ZINC22927169 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50023518 C([C@H]1CCNC(=N1)c1ccccc1)N1CCN(CC1)c1ccccc1 InChI=1S/C21H26N4/c1-3-7-18(8-4-1)21-22-12-11-19(23-21)17-24-13-15-25(16-14-24)20-9-5-2-6-10-20/h1-10,19H,11-17H2,(H,22,23)/t19-/m1/s1 BJWYIHWMKMZYRS-LJQANCHMSA-N 50124195 (R)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine::CHEMBL352925 D(2) dopamine receptor Homo sapiens 25000 ChEMBL 10.1016/s0960-894x(03)00004-0 10.7270/Q26T0N5V 12617906 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381216 104016552 CHEMBL352925 ZINC22453365 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50023519 C1CN(CCN1[C@@H]1CCNC(=NC1)c1ccccc1)c1ccccc1 InChI=1S/C21H26N4/c1-3-7-18(8-4-1)21-22-12-11-20(17-23-21)25-15-13-24(14-16-25)19-9-5-2-6-10-19/h1-10,20H,11-17H2,(H,22,23)/t20-/m1/s1 JCXPHDPIKCCHEL-HXUWFJFHSA-N 50124197 (R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-tetrahydro-1H-[1,3]diazepine::CHEMBL169562 D(2) dopamine receptor Homo sapiens 4200 ChEMBL 10.1016/s0960-894x(03)00004-0 10.7270/Q26T0N5V 12617906 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381424 104016554 CHEMBL169562 ZINC22927178 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50023520 COc1ccc(Br)cc1C1=N[C@H](CN2CCN(CC2)c2ccccc2)CCN1 InChI=1S/C22H27BrN4O/c1-28-21-8-7-17(23)15-20(21)22-24-10-9-18(25-22)16-26-11-13-27(14-12-26)19-5-3-2-4-6-19/h2-8,15,18H,9-14,16H2,1H3,(H,24,25)/t18-/m0/s1 RVBVZFLMCDGFOZ-SFHVURJKSA-N 50124191 (S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine::CHEMBL353220 D(2) dopamine receptor Homo sapiens 16000 ChEMBL 10.1016/s0960-894x(03)00004-0 10.7270/Q26T0N5V 12617906 Einsiedel, J; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124191&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381286 104016548 CHEMBL353220 ZINC22927165 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50031353 CN1CCc2cc(Cl)c(O)cc2[C@@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m0/s1 GOTMKOSCLKVOGG-HNNXBMFYSA-N 82248 CAS_73445-63-3::SCH 23388 (S-enantiomer) D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1021/jm00119a003 10.7270/Q2B56K9S 3263503 Baindur, N; Neumeyer, JL; Niznik, HB; Bzowej, NH; Jarvie, KR; Seeman, P; Garlick, RK; Miller, JJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603800 136350220 ZINC02017840 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033379 CCCN(CCc1ccc(Nc2ccc([N+]([O-])=O)c3n[o+][n-]c23)cc1)C1CCc2c(O)cccc2C1 InChI=1S/C27H29N5O4/c1-2-15-31(21-10-11-22-19(17-21)4-3-5-25(22)33)16-14-18-6-8-20(9-7-18)28-23-12-13-24(32(34)35)27-26(23)29-36-30-27/h3-9,12-13,21,28,33H,2,10-11,14-17H2,1H3 GAJLCVIQCPUCOK-UHFFFAOYSA-N 50010294 (R)6-({2-[4-(7-Nitro-benzo[1,2,5]oxadiazol-4-ylamino)-phenyl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(RS)6-({2-[4-(7-Nitro-benzo[1,2,5]oxadiazol-4-ylamino)-phenyl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)6-({2-[4-(7-Nitro-benzo[1,2,5]oxadiazol-4-ylamino)-phenyl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL109787::CHEMBL113196 D(2) dopamine receptor Homo sapiens 3.2 ChEMBL 10.1021/jm00115a012 10.7270/Q2KS6S5V 1956042 Bakthavachalam, V; Baindur, N; Madras, BK; Neumeyer, JL Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010294&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15115518 103923113 CHEMBL113196CHEMBL109787 ZINC13446574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033384 CCCN(CCc1ccc(C)cc1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C22H29NO/c1-3-14-23(15-13-18-9-7-17(2)8-10-18)20-11-12-21-19(16-20)5-4-6-22(21)24/h4-10,20,24H,3,11-16H2,1-2H3/t20-/m0/s1 OGGBZQYMCSUKHZ-FQEVSTJZSA-N 50453024 CHEMBL2092940 D(2) dopamine receptor Homo sapiens 6.7 ChEMBL 10.1021/jm00115a012 10.7270/Q2KS6S5V 1956042 Bakthavachalam, V; Baindur, N; Madras, BK; Neumeyer, JL Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70684965 225145815 CHEMBL2092940 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033385 CCCN(CCc1ccccc1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C21H27NO/c1-2-14-22(15-13-17-7-4-3-5-8-17)19-11-12-20-18(16-19)9-6-10-21(20)23/h3-10,19,23H,2,11-16H2,1H3/t19-/m0/s1 DEYFWGXTPWNADC-IBGZPJMESA-N 50453025 CHEMBL612083 D(2) dopamine receptor Homo sapiens 2.1 ChEMBL 10.1021/jm00115a012 10.7270/Q2KS6S5V 1956042 Bakthavachalam, V; Baindur, N; Madras, BK; Neumeyer, JL Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603954 225145816 CHEMBL612083 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033398 CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c1ccccc1 InChI=1S/C17H18ClNO2/c1-19-8-7-12-13(9-15(20)17(21)16(12)18)14(10-19)11-5-3-2-4-6-11/h2-6,9,14,20-21H,7-8,10H2,1H3 OZWXDWVFTIFZHS-UHFFFAOYSA-N 50007702 6-Chloro-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide::CHEMBL543398 D(2) dopamine receptor Homo sapiens 77.0 ChEMBL 10.1021/jm00116a004 10.7270/Q26H4J17 1684995 Neumeyer, JL; Baindur, N; Niznik, HB; Guan, HC; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007702&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130844 103920972 CHEMBL543398 ZINC05966783 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033401 Oc1cc2C(CNCCc2c(Cl)c1O)c1ccccc1 InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2 GHWJEDJMOVUXEC-UHFFFAOYSA-N 86282 6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide::CAS_1218::CHEMBL553503::NSC_1218::SKF 81297::cid_11957706 D(2) dopamine receptor Homo sapiens 310 ChEMBL 10.1021/jm00116a004 10.7270/Q26H4J17 1684995 Neumeyer, JL; Baindur, N; Niznik, HB; Guan, HC; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SK0 7LJC,7JV5 1218 136352382 CHEMBL553503 938 ZINC03783980 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033402 Oc1cc2C(CNCCc2c(Br)c1O)c1ccccc1 InChI=1S/C16H16BrNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2 XKTGLDSNABUNGD-UHFFFAOYSA-N 50007698 6-Bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide::CHEMBL541559 D(2) dopamine receptor Homo sapiens 39 ChEMBL 10.1021/jm00116a004 10.7270/Q26H4J17 1684995 Neumeyer, JL; Baindur, N; Niznik, HB; Guan, HC; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9819042 103920968 CHEMBL541559 ZINC13447136 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033403 Oc1cc2C(CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2 HJWHHQIVUHOBQN-UHFFFAOYSA-N 50004917 3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide(Cl-APB)::CHEMBL35354::CHEMBL544115::RS(+/-)-6-Cl-APB3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SKF 82958 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1021/jm00116a004 10.7270/Q26H4J17 1684995 Neumeyer, JL; Baindur, N; Niznik, HB; Guan, HC; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1225 103918464 CHEMBL35354CHEMBL544115 ZINC03870318 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033404 CN1CCc2c(Br)c(O)c(O)cc2C(C1)c1ccccc1 InChI=1S/C17H18BrNO2/c1-19-8-7-12-13(9-15(20)17(21)16(12)18)14(10-19)11-5-3-2-4-6-11/h2-6,9,14,20-21H,7-8,10H2,1H3 DHKYCFXOSLNAFZ-UHFFFAOYSA-N 50007700 6-Bromo-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide::CHEMBL554009 D(2) dopamine receptor Homo sapiens 4000 ChEMBL 10.1021/jm00116a004 10.7270/Q26H4J17 1684995 Neumeyer, JL; Baindur, N; Niznik, HB; Guan, HC; Seeman, P Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007700&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13697621 103920970 CHEMBL554009 ZINC13447142 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50033255 C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m0/s1 UYNVMODNBIQBMV-KKSFZXQISA-N 50007674 (+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::(-)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::4-[(1R,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::4-[(R)-2-(4-Benzyl-piperidin-1-yl)-1-(S)-hydroxy-propyl]-phenol::4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::CHEMBL49623::Ifenprodil::Ifenprodil,(+/-) D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm00114a018 10.7270/Q2FN155W 1681106 Chenard, BL; Shalaby, IA; Koe, BK; Ronau, RT; Butler, TW; Prochniak, MA; Schmidt, AW; Fox, CB Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007674&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search QEL 4PE5,3QEL,7AQI,5EWJ 6604117 103920944 CHEMBL49623 ZINC00014669 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50037001 C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1 XBGWTWPYCTZIIE-HXUWFJFHSA-N 50048299 4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL335545::CI-1007 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127698 103978825 CHEMBL335545 ZINC03792322 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036393 CN1CCC(=CC1)C1=Cc2ccccc2C(=C(C)C)c2ccccc12 InChI=1S/C24H25N/c1-17(2)24-20-9-5-4-8-19(20)16-23(18-12-14-25(3)15-13-18)21-10-6-7-11-22(21)24/h4-12,16H,13-15H2,1-3H3 BFTXVLUTUUBYLQ-UHFFFAOYSA-N 50036443 4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine::CHEMBL94067 D(2) dopamine receptor Homo sapiens 520 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10449136 103944208 CHEMBL94067 ZINC13738227 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036415 FC(F)(F)S(=O)(=O)Oc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H18F3NO3S/c1-2-9-20-10-8-12-11-4-3-5-15(13(11)6-7-14(12)20)23-24(21,22)16(17,18)19/h2-5,12,14H,1,6-10H2/t12-,14+/m1/s1 JNAGEIMWCSOQKU-OCCSQVGLSA-N 50453388 CHEMBL2111566 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453388&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10428654 225145937 CHEMBL2111566 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036416 CCCN1CCC[C@H](C1)c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C16H26N2O2S/c1-4-10-18-11-6-8-15(13-18)14-7-5-9-16(12-14)21(19,20)17(2)3/h5,7,9,12,15H,4,6,8,10-11,13H2,1-3H3/t15-/m1/s1 KXDIYSZQVVAYOA-OAHLLOKOSA-N 50039738 CHEMBL329443::N,N-Dimethyl-3-((S)-1-propyl-piperidin-3-yl)-benzenesulfonamide D(2) dopamine receptor Homo sapiens 227 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10018300 103946933 CHEMBL329443 ZINC13738267 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036418 COc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1 ZRAGXRIXRXDXCR-HIFRSBDPSA-N 50453387 CHEMBL566970 D(2) dopamine receptor Homo sapiens >339 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453387&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10060349 225145936 CHEMBL566970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036420 CCCN1CCC[C@H](C1)c1cccc(OC)c1 InChI=1S/C15H23NO/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)17-2/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3/t14-/m1/s1 IOENUXNLWXMOQG-CQSZACIVSA-N 50039740 (S)-3-(3-Methoxy-phenyl)-1-propyl-piperidine::CHEMBL93582 D(2) dopamine receptor Homo sapiens 602 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039740&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937927 103946935 CHEMBL93582 ZINC13738257 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036422 N#Cc1cccc(c1)[C@@H]1CCCNC1 InChI=1S/C12H14N2/c13-8-10-3-1-4-11(7-10)12-5-2-6-14-9-12/h1,3-4,7,12,14H,2,5-6,9H2/t12-/m1/s1 RDRGDNFLGKTNOF-GFCCVEGCSA-N 50039756 (S)-3-Piperidin-3-yl-benzonitrile::CHEMBL93682 D(2) dopamine receptor Homo sapiens 314 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10397550 103946951 CHEMBL93682 ZINC03785172 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036423 CN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C13H16N2/c1-15-7-3-6-13(10-15)12-5-2-4-11(8-12)9-14/h2,4-5,8,13H,3,6-7,10H2,1H3/t13-/m1/s1 WTTCSLJBJDWDOC-CYBMUJFWSA-N 50039766 3-((S)-1-Methyl-piperidin-3-yl)-benzonitrile::CHEMBL90662 D(2) dopamine receptor Homo sapiens 1040 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10330427 103946961 CHEMBL90662 ZINC13738274 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036424 CCCN1CCC[C@H](C1)c1cccc(CO)c1 InChI=1S/C15H23NO/c1-2-8-16-9-4-7-15(11-16)14-6-3-5-13(10-14)12-17/h3,5-6,10,15,17H,2,4,7-9,11-12H2,1H3/t15-/m1/s1 BOTMSPLRFWVABA-OAHLLOKOSA-N 50039744 CHEMBL93101::[3-((S)-1-Propyl-piperidin-3-yl)-phenyl]-methanol D(2) dopamine receptor Homo sapiens 240 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039744&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10263410 103946939 CHEMBL93101 ZINC13738262 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036425 CCCN1CCC[C@H](C1)c1cccc(OCC(F)(F)F)c1 InChI=1S/C16H22F3NO/c1-2-8-20-9-4-6-14(11-20)13-5-3-7-15(10-13)21-12-16(17,18)19/h3,5,7,10,14H,2,4,6,8-9,11-12H2,1H3/t14-/m1/s1 RMFLBNXQMNGIHR-CQSZACIVSA-N 50039748 (S)-1-Propyl-3-[3-(2,2,2-trifluoro-ethoxy)-phenyl]-piperidine::CHEMBL93946 D(2) dopamine receptor Homo sapiens 820 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039748&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10380129 103946943 CHEMBL93946 ZINC13738258 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036427 CCCN1CCC[C@H](C1)c1cccc(c1)-c1ccsc1 InChI=1S/C18H23NS/c1-2-9-19-10-4-7-17(13-19)15-5-3-6-16(12-15)18-8-11-20-14-18/h3,5-6,8,11-12,14,17H,2,4,7,9-10,13H2,1H3/t17-/m1/s1 WKZQYOGJYMCSPM-QGZVFWFLSA-N 50039765 (S)-1-Propyl-3-(3-thiophen-3-yl-phenyl)-piperidine::CHEMBL314536 D(2) dopamine receptor Homo sapiens 134 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11778702 103946960 CHEMBL314536 ZINC13738271 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036428 C=CCN1CCC2C1CCc1c(cccc21)C#N InChI=1S/C16H18N2/c1-2-9-18-10-8-15-14-5-3-4-12(11-17)13(14)6-7-16(15)18/h2-5,15-16H,1,6-10H2 ZOXQOLDAOFYVMZ-UHFFFAOYSA-N 50039762 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carbonitrile::CHEMBL92939 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039762&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325894 103946957 CHEMBL92939 ZINC26665598 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036429 NC(=O)c1cccc2C3CCN(CC=C)C3CCc12 InChI=1S/C16H20N2O/c1-2-9-18-10-8-13-11-4-3-5-14(16(17)19)12(11)6-7-15(13)18/h2-5,13,15H,1,6-10H2,(H2,17,19) ITRJBWXLLLCDGV-UHFFFAOYSA-N 50039771 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carboxylic acid amide::CHEMBL96726 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325900 103946966 CHEMBL96726 ZINC40461387 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036430 CCCN1CCC[C@H](C1)c1cccc(c1)S(C)(=O)=O InChI=1S/C15H23NO2S/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)19(2,17)18/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3/t14-/m1/s1 GZVBVBMMNFIXGE-CQSZACIVSA-N 50039749 (S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidine::(S)-3-(3-Methanesulfonyl-phenyl)-1-propyl-piperidine::CHEMBL311730 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039749&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9795741 103946944 CHEMBL311730 ZINC03811315 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036433 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Homo sapiens 8.5 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036435 COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1 ZRAGXRIXRXDXCR-UKRRQHHQSA-N 50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037436 103942565 CHEMBL24222 ZINC13826504 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036436 COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1 ZRAGXRIXRXDXCR-UKRRQHHQSA-N 50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222 D(2) dopamine receptor Homo sapiens 50 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037436 103942565 CHEMBL24222 ZINC13826504 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036437 CCc1sccc1N1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C18H20N2S/c1-2-18-17(8-10-21-18)20-9-4-7-16(13-20)15-6-3-5-14(11-15)12-19/h3,5-6,8,10-11,16H,2,4,7,9,13H2,1H3/t16-/m1/s1 FLHNFXPLCFJIDJ-MRXNPFEDSA-N 50039763 3-[(S)-1-(2-Ethyl-thiophen-3-yl)-piperidin-3-yl]-benzonitrile::CHEMBL93570 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039763&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325908 103946958 CHEMBL93570 ZINC26658470 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036439 N#Cc1cccc(c1)[C@@H]1CCCN(CCCc2ccccc2)C1 InChI=1S/C21H24N2/c22-16-19-9-4-11-20(15-19)21-12-6-14-23(17-21)13-5-10-18-7-2-1-3-8-18/h1-4,7-9,11,15,21H,5-6,10,12-14,17H2/t21-/m1/s1 JSFVESKREDQPEC-OAQYLSRUSA-N 50039735 3-[(S)-1-(3-Phenyl-propyl)-piperidin-3-yl]-benzonitrile::CHEMBL94811 D(2) dopamine receptor Homo sapiens 29 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086395 103946930 CHEMBL94811 ZINC13738280 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036440 C#CCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C15H16N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h1,3,5-6,10,15H,4,7-9,12H2/t15-/m1/s1 WIXVSIWFYYDDMJ-OAHLLOKOSA-N 50039745 3-((S)-1-Prop-2-ynyl-piperidin-3-yl)-benzonitrile::CHEMBL91228 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039745&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9991216 103946940 CHEMBL91228 ZINC13738276 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036441 CCCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C15H20N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h3,5-6,10,15H,2,4,7-9,12H2,1H3/t15-/m1/s1 GQRIAOUUYRIMLH-OAHLLOKOSA-N 50039769 3-((S)-1-Propyl-piperidin-3-yl)-benzonitrile::CHEMBL92183 D(2) dopamine receptor Homo sapiens 265 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039769&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816005 103946964 CHEMBL92183 ZINC03785159 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036442 CCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C14H18N2/c1-2-16-8-4-7-14(11-16)13-6-3-5-12(9-13)10-15/h3,5-6,9,14H,2,4,7-8,11H2,1H3/t14-/m1/s1 OPZKYIOCNPKDBN-CQSZACIVSA-N 50039758 3-((S)-1-Ethyl-piperidin-3-yl)-benzonitrile::CHEMBL90798 D(2) dopamine receptor Homo sapiens 235 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039758&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353207 103946953 CHEMBL90798 ZINC13738275 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036443 CCCN1CCC[C@H](C1)c1cccc(OS(C)(=O)=O)c1 InChI=1S/C15H23NO3S/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)19-20(2,17)18/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3/t14-/m1/s1 AHSLTJCTFBJCMT-CQSZACIVSA-N 50039747 CHEMBL93594::Methanesulfonic acid 3-((S)-1-propyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039747&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402381 103946942 CHEMBL93594 ZINC13738259 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036444 CCCN1CCC[C@H](C1)c1cccc(c1)C(N)=O InChI=1S/C15H22N2O/c1-2-8-17-9-4-7-14(11-17)12-5-3-6-13(10-12)15(16)18/h3,5-6,10,14H,2,4,7-9,11H2,1H3,(H2,16,18)/t14-/m1/s1 CJCQHAUDAPOVBD-CQSZACIVSA-N 50039761 3-((S)-1-Propyl-piperidin-3-yl)-benzamide::CHEMBL92232 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10467118 103946956 CHEMBL92232 ZINC13738263 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036445 CCCN1CCC[C@H](C1)c1cccc(c1)C(=O)OC InChI=1S/C16H23NO2/c1-3-9-17-10-5-8-15(12-17)13-6-4-7-14(11-13)16(18)19-2/h4,6-7,11,15H,3,5,8-10,12H2,1-2H3/t15-/m1/s1 ZWNHEPFDYRKYSD-OAHLLOKOSA-N 50039753 3-((S)-1-Propyl-piperidin-3-yl)-benzoic acid methyl ester::CHEMBL93900 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039753&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10355305 103946948 CHEMBL93900 ZINC13738261 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036446 CCCN1CCC[C@H](C1)c1cccc(c1)C(C)=O InChI=1S/C16H23NO/c1-3-9-17-10-5-8-16(12-17)15-7-4-6-14(11-15)13(2)18/h4,6-7,11,16H,3,5,8-10,12H2,1-2H3/t16-/m1/s1 BBRKEERFZOYHTK-MRXNPFEDSA-N 50039764 1-[3-((S)-1-Propyl-piperidin-3-yl)-phenyl]-ethanone::CHEMBL90797 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377227 103946959 CHEMBL90797 ZINC13738272 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036448 COc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1 ZRAGXRIXRXDXCR-HIFRSBDPSA-N 50453387 CHEMBL566970 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453387&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10060349 225145936 CHEMBL566970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036449 CCCN1CCC[C@H](C1)c1cccc(CC#N)c1 InChI=1S/C16H22N2/c1-2-10-18-11-4-7-16(13-18)15-6-3-5-14(12-15)8-9-17/h3,5-6,12,16H,2,4,7-8,10-11,13H2,1H3/t16-/m1/s1 RURTXDUFVIOALE-MRXNPFEDSA-N 50039741 CHEMBL93917::[3-((S)-1-Propyl-piperidin-3-yl)-phenyl]-acetonitrile D(2) dopamine receptor Homo sapiens 69 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039741&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466922 103946936 CHEMBL93917 ZINC13738269 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036450 CCC(C)N1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C16H22N2/c1-3-13(2)18-9-5-8-16(12-18)15-7-4-6-14(10-15)11-17/h4,6-7,10,13,16H,3,5,8-9,12H2,1-2H3/t13?,16-/m1/s1 TYYIXERJKMDZBL-FQNRMIAFSA-N 50039778 3-((S)-1-sec-Butyl-piperidin-3-yl)-benzonitrile::CHEMBL413483 D(2) dopamine receptor Homo sapiens 187 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466923 103946973 CHEMBL413483 ZINC13738278 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036452 N#Cc1cccc(c1)[C@@H]1CCCN(CCc2ccccc2)C1 InChI=1S/C20H22N2/c21-15-18-8-4-9-19(14-18)20-10-5-12-22(16-20)13-11-17-6-2-1-3-7-17/h1-4,6-9,14,20H,5,10-13,16H2/t20-/m1/s1 BARYHSADJVEXIX-HXUWFJFHSA-N 50039751 3-((S)-1-Phenethyl-piperidin-3-yl)-benzonitrile::CHEMBL93646 D(2) dopamine receptor Homo sapiens 22 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039751&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10334422 103946946 CHEMBL93646 ZINC13738279 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036453 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m0/s1 ZRAGXRIXRXDXCR-DZGCQCFKSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 ZINC00004906 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036454 C=CCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C15H18N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h2-3,5-6,10,15H,1,4,7-9,12H2/t15-/m1/s1 LWSMSVQQKULODQ-OAHLLOKOSA-N 50039739 3-((S)-1-Allyl-piperidin-3-yl)-benzonitrile::CHEMBL93212 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10242819 103946934 CHEMBL93212 ZINC03785169 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036456 CC(C)N1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C15H20N2/c1-12(2)17-8-4-7-15(11-17)14-6-3-5-13(9-14)10-16/h3,5-6,9,12,15H,4,7-8,11H2,1-2H3/t15-/m1/s1 MCWNRJVMXBUUPG-OAHLLOKOSA-N 50039759 3-((S)-1-Isopropyl-piperidin-3-yl)-benzonitrile::CHEMBL93383 D(2) dopamine receptor Homo sapiens 106 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105186 103946954 CHEMBL93383 ZINC03785165 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036457 N#Cc1cccc(c1)[C@@H]1CCCN(CC2CC2)C1 InChI=1S/C16H20N2/c17-10-14-3-1-4-15(9-14)16-5-2-8-18(12-16)11-13-6-7-13/h1,3-4,9,13,16H,2,5-8,11-12H2/t16-/m1/s1 RWFSSGIYTQCWMB-MRXNPFEDSA-N 50039772 3-((S)-1-Cyclopropylmethyl-piperidin-3-yl)-benzonitrile::CHEMBL328894 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037311 103946967 CHEMBL328894 ZINC12355935 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50036458 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m0/s1 ZRAGXRIXRXDXCR-DZGCQCFKSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 D(2) dopamine receptor Homo sapiens >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 ZINC00004906 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50037587 CCCN(C\C=C\I)C1COc2c(O)cccc2C1 InChI=1S/C15H20INO2/c1-2-8-17(9-4-7-16)13-10-12-5-3-6-14(18)15(12)19-11-13/h3-7,13,18H,2,8-11H2,1H3/b7-4+ ONVPKPUWGYFERX-QPJJXVBHSA-N 50038279 3-[((E)-3-Iodo-allyl)-propyl-amino]-chroman-8-ol::CHEMBL133085 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406989 103945716 CHEMBL133085 ZINC13739890 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50037588 CCCN(C\C=C\I)C1CCc2c(O)cccc2C1 InChI=1S/C16H22INO/c1-2-10-18(11-4-9-17)14-7-8-15-13(12-14)5-3-6-16(15)19/h3-6,9,14,19H,2,7-8,10-12H2,1H3/b9-4+ LYFXQSOWXVVQIV-RUDMXATFSA-N 50038278 6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL263282 D(2) dopamine receptor Homo sapiens 3.6 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10451844 103945715 CHEMBL263282 ZINC13739884 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50037589 CCCN(C\C=C\I)C1CCc2cc(O)ccc2C1 InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-14-12-16(19)7-5-13(14)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+ AQKFTLWWZGTUKW-FPYGCLRLSA-N 50038280 6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL336851 D(2) dopamine receptor Homo sapiens 547 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9999267 103945717 CHEMBL336851 ZINC13739886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50037590 CCCN(C\C=C\I)C1CCc2ccc(O)cc2C1 InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+ RTMIJLQPWFKAFE-FPYGCLRLSA-N 50038276 (R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::7-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL110239 D(2) dopamine receptor Homo sapiens 6.6 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6305587 103945713 64137 CHEMBL110239 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50037591 O=C(N[C@H]1CC[C@H]2C[C@H](CC[C@@H]2C1)N1CCN(CC1)c1ccccn1)c1ccccc1 InChI=1S/C26H34N4O/c31-26(20-6-2-1-3-7-20)28-23-11-9-22-19-24(12-10-21(22)18-23)29-14-16-30(17-15-29)25-8-4-5-13-27-25/h1-8,13,21-24H,9-12,14-19H2,(H,28,31)/t21-,22+,23+,24+/m1/s1 OVQXIVRARLGKOO-SBFWRKJZSA-N 50453480 CHEMBL2112745 D(2) dopamine receptor Homo sapiens 240 ChEMBL 10.1021/jm00050a022 10.7270/Q2SN09KN 7990124 Wustrow, DJ; Wise, LD; Cody, DM; MacKenzie, RG; Georgic, LM; Pugsley, TA; Heffner, TG Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025039 225145950 CHEMBL2112745 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039776 CCCN(CCC)C1CCc2[nH]ncc2C1 InChI=1S/C13H23N3/c1-3-7-16(8-4-2)12-5-6-13-11(9-12)10-14-15-13/h10,12H,3-9H2,1-2H3,(H,14,15) GLKCCTUKWPNZKT-UHFFFAOYSA-N 50032642 CHEMBL318740::Dipropyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine D(2) dopamine receptor Homo sapiens 523 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12898419 103941097 CHEMBL318740 ZINC13742646 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039777 CCCN(CCC)C1CCc2cc(OC)ccc2C1 InChI=1S/C17H27NO/c1-4-10-18(11-5-2)16-8-6-15-13-17(19-3)9-7-14(15)12-16/h7,9,13,16H,4-6,8,10-12H2,1-3H3 SMAYDEMZELAUEB-UHFFFAOYSA-N 50032639 (6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL106047 D(2) dopamine receptor Homo sapiens 3940 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12741429 103941094 CHEMBL106047 ZINC26847736 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039778 CCCN(CCC)C1CCc2cc(OC)ccc2C1 InChI=1S/C17H27NO/c1-4-10-18(11-5-2)16-8-6-15-13-17(19-3)9-7-14(15)12-16/h7,9,13,16H,4-6,8,10-12H2,1-3H3 SMAYDEMZELAUEB-UHFFFAOYSA-N 50032639 (6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL106047 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12741429 103941094 CHEMBL106047 ZINC26847736 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039779 CCCN(CCC)C1CCc2nc(N)sc2C1 InChI=1S/C13H23N3S/c1-3-7-16(8-4-2)10-5-6-11-12(9-10)17-13(14)15-11/h10H,3-9H2,1-2H3,(H2,14,15) ABRFKTAFRQVZBR-UHFFFAOYSA-N 50032643 CHEMBL105512::N*6*,N*6*-Dipropyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine D(2) dopamine receptor Homo sapiens 57 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13670706 103941098 CHEMBL105512 ZINC13742644 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039780 CCCN(CCC)C1CCc2ncccc2C1 InChI=1S/C15H24N2/c1-3-10-17(11-4-2)14-7-8-15-13(12-14)6-5-9-16-15/h5-6,9,14H,3-4,7-8,10-12H2,1-2H3 YEYNJASJMPEAEX-UHFFFAOYSA-N 50032641 CHEMBL105977::Dipropyl-(5,6,7,8-tetrahydro-quinolin-6-yl)-amine D(2) dopamine receptor Homo sapiens 466 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105359 103941096 CHEMBL105977 ZINC13742648 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039781 CCCN(CCC)C1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3 MDBWEQVKJDMEMK-UHFFFAOYSA-N 50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273 D(2) dopamine receptor Homo sapiens 6 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172267 103931135 CHEMBL273273 128 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039782 CCCN(CCC)C1CCc2ncccc2C1 InChI=1S/C15H24N2/c1-3-10-17(11-4-2)14-7-8-15-13(12-14)6-5-9-16-15/h5-6,9,14H,3-4,7-8,10-12H2,1-2H3 YEYNJASJMPEAEX-UHFFFAOYSA-N 50032641 CHEMBL105977::Dipropyl-(5,6,7,8-tetrahydro-quinolin-6-yl)-amine D(2) dopamine receptor Homo sapiens 466 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105359 103941096 CHEMBL105977 ZINC13742648 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039901 CCCc1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C18H21NO2S/c1-2-3-11-7-13-17(22-11)9-19-14-5-4-10-6-15(20)16(21)8-12(10)18(13)14/h6-8,14,18-21H,2-5,9H2,1H3/t14-,18+/m0/s1 REHAKLRYABHSQJ-KBXCAEBGSA-N 50033115 (5aS,11bR)-2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol; hydrochloride::CHEMBL2115374::CHEMBL544814 D(2) dopamine receptor Homo sapiens 4020 ChEMBL 10.1021/jm00018a002 10.7270/Q26M37G0 7658429 Michaelides, MR; Hong, Y; DiDomenico, S; Asin, KE; Britton, DR; Lin, CW; Williams, M; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033115&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796958 103941456 CHEMBL2115374CHEMBL544814 ZINC01539970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039902 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1021/jm00018a002 10.7270/Q26M37G0 7658429 Michaelides, MR; Hong, Y; DiDomenico, S; Asin, KE; Britton, DR; Lin, CW; Williams, M; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039905 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 260 ChEMBL 10.1021/jm00018a002 10.7270/Q26M37G0 7658429 Michaelides, MR; Hong, Y; DiDomenico, S; Asin, KE; Britton, DR; Lin, CW; Williams, M; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039907 CCCc1cc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C18H21NO2S/c1-2-3-11-7-13-17(22-11)9-19-14-5-4-10-6-15(20)16(21)8-12(10)18(13)14/h6-8,14,18-21H,2-5,9H2,1H3/t14-,18+/m1/s1 REHAKLRYABHSQJ-KDOFPFPSSA-N 50033114 (5aR,11bS)-2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::A-86929::CHEMBL28338 D(2) dopamine receptor Homo sapiens 3900 ChEMBL 10.1021/jm00018a002 10.7270/Q26M37G0 7658429 Michaelides, MR; Hong, Y; DiDomenico, S; Asin, KE; Britton, DR; Lin, CW; Williams, M; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033114&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9841398 103941455 CHEMBL28338 ZINC00019656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039913 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)C12CC3CC(CC(C3)C1)C2 InChI=1S/C20H27NO3/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20/h1-2,11-13,17-18,22-23H,3-10,21H2/t11?,12?,13?,17-,18-,20?/m0/s1 QLJOSZATCBCBDR-DFKUFRTHSA-N 50033116 (1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol::A-77636::CHEMBL291143::cid_6603703 D(2) dopamine receptor Homo sapiens >4000 ChEMBL 10.1021/jm00018a002 10.7270/Q26M37G0 7658429 Michaelides, MR; Hong, Y; DiDomenico, S; Asin, KE; Britton, DR; Lin, CW; Williams, M; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033116&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G3O 7CKX 6603703 103941457 64080 CHEMBL291143 ZINC03782517 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50039914 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Homo sapiens 1610 ChEMBL 10.1021/jm00018a002 10.7270/Q26M37G0 7658429 Michaelides, MR; Hong, Y; DiDomenico, S; Asin, KE; Britton, DR; Lin, CW; Williams, M; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041172 Oc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 InChI=1S/C24H27NO/c26-24-11-9-21(10-12-24)23-8-4-5-19(17-23)18-25-15-13-22(14-16-25)20-6-2-1-3-7-20/h1-3,6-13,19,26H,4-5,14-18H2/t19-/m1/s1 GHLIXCKZQCRDAX-LJQANCHMSA-N 50048302 4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-cyclohex-1-enyl]-phenol::CHEMBL357416 D(2) dopamine receptor Homo sapiens 3.5 ChEMBL 10.1021/jm00026a007 10.7270/Q2VQ31SG 8544176 Wright, JL; Downing, DM; Feng, MR; Hayes, RN; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 178078 103978828 CHEMBL357416 ZINC06096034 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041173 Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccccc2)CC1 InChI=1S/C24H27NO/c26-24-11-9-21(10-12-24)22-13-15-25(16-14-22)18-19-5-4-8-23(17-19)20-6-2-1-3-7-20/h1-3,6-13,19,26H,4-5,14-18H2/t19-/m1/s1 RIRRORJZVJGNAL-LJQANCHMSA-N 50048301 4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-phenol::CHEMBL356269 D(2) dopamine receptor Homo sapiens 5.7 ChEMBL 10.1021/jm00026a007 10.7270/Q2VQ31SG 8544176 Wright, JL; Downing, DM; Feng, MR; Hayes, RN; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10759963 103978827 CHEMBL356269 ZINC13603953 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041174 Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccc(O)cc2)CC1 InChI=1S/C24H27NO2/c26-23-8-4-19(5-9-23)21-12-14-25(15-13-21)17-18-2-1-3-22(16-18)20-6-10-24(27)11-7-20/h3-12,18,26-27H,1-2,13-17H2/t18-/m1/s1 VMTIAIJOJOQAEM-GOSISDBHSA-N 50048300 4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-tetrahydro pyridin-4-yl)phenol::CHEMBL147159 D(2) dopamine receptor Homo sapiens 2.2 ChEMBL 10.1021/jm00026a007 10.7270/Q2VQ31SG 8544176 Wright, JL; Downing, DM; Feng, MR; Hayes, RN; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10713620 103978826 CHEMBL147159 ZINC13603955 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041175 C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1 XBGWTWPYCTZIIE-HXUWFJFHSA-N 50048299 4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL335545::CI-1007 D(2) dopamine receptor Homo sapiens 8.4 ChEMBL 10.1021/jm00026a007 10.7270/Q2VQ31SG 8544176 Wright, JL; Downing, DM; Feng, MR; Hayes, RN; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127698 103978825 CHEMBL335545 ZINC03792322 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043827 CCCN(CCC)[C@H]1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m0/s1 BLYMJBIZMIGWFK-HNNXBMFYSA-N 50454427 CHEMBL305706 D(2) dopamine receptor Homo sapiens 4777 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23928184 225146216 CHEMBL305706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043830 CCCN(CCc1ccsc1)C1CCc2c(O)cccc2C1 InChI=1S/C19H25NOS/c1-2-10-20(11-8-15-9-12-22-14-15)17-6-7-18-16(13-17)4-3-5-19(18)21/h3-5,9,12,14,17,21H,2,6-8,10-11,13H2,1H3 RHRKSVACMIQFDY-UHFFFAOYSA-N 50010621 6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL7806 D(2) dopamine receptor Homo sapiens 24 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010621&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128054 103923395 CHEMBL7806 ZINC05833419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043833 CCCN(CCC)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1 MDBWEQVKJDMEMK-AWEZNQCLSA-N 50115277 (2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2R,3S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-(-)-5-hydroxy-2-(N,N-di-n-propylamino)tetralin::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL269004 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11299620 104009254 CHEMBL269004 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043842 CN(C)C1CCc2ccc(O)cc2C1 InChI=1S/C12H17NO/c1-13(2)11-5-3-9-4-6-12(14)8-10(9)7-11/h4,6,8,11,14H,3,5,7H2,1-2H3 YVQFTRVYMAREIA-UHFFFAOYSA-N 50054076 7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL135932 D(2) dopamine receptor Homo sapiens 5.4 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054076&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10559624 103950734 CHEMBL135932 ZINC13759811 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043844 CCCNC1CCc2ccc(O)cc2C1 InChI=1S/C13H19NO/c1-2-7-14-12-5-3-10-4-6-13(15)9-11(10)8-12/h4,6,9,12,14-15H,2-3,5,7-8H2,1H3 NBGJODUAUISAEF-UHFFFAOYSA-N 50054077 7-Propylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL336652 D(2) dopamine receptor Homo sapiens 3.8 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054077&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10058787 103950735 CHEMBL336652 ZINC13759809 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043851 CCCN(CCC)[C@H]1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m0/s1 BLYMJBIZMIGWFK-HNNXBMFYSA-N 50454427 CHEMBL305706 D(2) dopamine receptor Homo sapiens 275 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23928184 225146216 CHEMBL305706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043852 CCN(C)C1CCc2ccc(O)cc2C1 InChI=1S/C13H19NO/c1-3-14(2)12-6-4-10-5-7-13(15)9-11(10)8-12/h5,7,9,12,15H,3-4,6,8H2,1-2H3 MXGQNMMTNCYAQF-UHFFFAOYSA-N 50054069 7-(Ethyl-methyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL134571 D(2) dopamine receptor Homo sapiens 173 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054069&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10512444 103950727 CHEMBL134571 ZINC13759813 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043853 CCCN(CCc1cccs1)[C@H]1CCc2ccc(OC)cc2C1 InChI=1S/C20H27NOS/c1-3-11-21(12-10-20-5-4-13-23-20)18-8-6-16-7-9-19(22-2)15-17(16)14-18/h4-5,7,9,13,15,18H,3,6,8,10-12,14H2,1-2H3/t18-/m0/s1 OWXFTDUHWKXJTL-SFHVURJKSA-N 50054068 ((S)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-(2-thiophen-2-yl-ethyl)-amine::CHEMBL133938 D(2) dopamine receptor Homo sapiens 250 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054068&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355355 103950726 CHEMBL133938 ZINC13759805 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043854 CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1 BLYMJBIZMIGWFK-OAHLLOKOSA-N 50054067 (2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT)::(R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL301559 D(2) dopamine receptor Homo sapiens 56 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603867 103950725 CHEMBL301559 ZINC03870310 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043855 CCCN1COC[C@H]2[C@H]1COc1ccc(O)cc21 InChI=1S/C14H19NO3/c1-2-5-15-9-17-7-12-11-6-10(16)3-4-14(11)18-8-13(12)15/h3-4,6,12-13,16H,2,5,7-9H2,1H3/t12-,13-/m1/s1 ZFSOBPVEIKTNQS-CHWSQXEVSA-N 50369174 CHEMBL94015::PD-128907 D(2) dopamine receptor Homo sapiens 1183 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324980 160848276 CHEMBL94015 ZINC26655017 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043856 NC1CCc2ccc(O)cc2C1 InChI=1S/C10H13NO/c11-9-3-1-7-2-4-10(12)6-8(7)5-9/h2,4,6,9,12H,1,3,5,11H2 VIYAPIMIOKKYNF-UHFFFAOYSA-N 50020503 7-Amino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL133830 D(2) dopamine receptor Homo sapiens 3.3 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10942784 103931319 CHEMBL133830 ZINC13759807 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043858 CCCN(CCC)[C@@H]1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m1/s1 MDBWEQVKJDMEMK-CQSZACIVSA-N 50054071 (R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL15146 D(2) dopamine receptor Homo sapiens 90 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12280580 103950729 CHEMBL15146 ZINC05832993 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043859 CCCNC1CCc2c(O)cccc2C1 InChI=1S/C13H19NO/c1-2-8-14-11-6-7-12-10(9-11)4-3-5-13(12)15/h3-5,11,14-15H,2,6-9H2,1H3 VCYPZWCFSAHTQT-UHFFFAOYSA-N 50054070 6-Propylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL334472 D(2) dopamine receptor Homo sapiens 0.50 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054070&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10375676 103950728 CHEMBL334472 ZINC13759799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043860 CCCN(CCc1cccs1)C1CCc2ccc(O)cc2C1 InChI=1S/C19H25NOS/c1-2-10-20(11-9-19-4-3-12-22-19)17-7-5-15-6-8-18(21)14-16(15)13-17/h3-4,6,8,12,14,17,21H,2,5,7,9-11,13H2,1H3 FKPNKWMJMHRBGE-UHFFFAOYSA-N 50054082 7-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL135954 D(2) dopamine receptor Homo sapiens 0.76 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054082&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10041417 103950740 CHEMBL135954 ZINC13759817 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043861 CCCN(C)C1CCc2ccc(O)cc2C1 InChI=1S/C14H21NO/c1-3-8-15(2)13-6-4-11-5-7-14(16)10-12(11)9-13/h5,7,10,13,16H,3-4,6,8-9H2,1-2H3 UKKJJXAEHLPZSM-UHFFFAOYSA-N 50054075 7-(Methyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL335392 D(2) dopamine receptor Homo sapiens 0.67 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054075&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10704110 103950733 CHEMBL335392 ZINC13759815 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043864 CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C21H27NO/c1-2-14-22(15-13-17-7-4-3-5-8-17)19-11-12-20-18(16-19)9-6-10-21(20)23/h3-10,19,23H,2,11-16H2,1H3 DEYFWGXTPWNADC-UHFFFAOYSA-N 50010289 (R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(RS)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL109684::N-0434 D(2) dopamine receptor Homo sapiens 0.50 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1240 103923108 CHEMBL109684 ZINC02169418 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043865 CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C19H25NOS/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21/h3-7,13,16,21H,2,8-12,14H2,1H3/t16-/m0/s1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 50123626 (S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL1303::Neupro::ROTIGOTINE D(2) dopamine receptor Homo sapiens 0.06 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123626&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search R5F 59227 104016053 CHEMBL1303 ZINC00004028 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50043867 CCCN(CCC)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1 MDBWEQVKJDMEMK-AWEZNQCLSA-N 50115277 (2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2R,3S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-(-)-5-hydroxy-2-(N,N-di-n-propylamino)tetralin::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL269004 D(2) dopamine receptor Homo sapiens 6 ChEMBL 10.1021/jm960345l 10.7270/Q21C1XJF 8863800 van Vliet, LA; Tepper, PG; Dijkstra, D; Damsma, G; Wikstrom, H; Pugsley, TA; Akunne, HC; Heffner, TG; Glase, SA; Wise, LD University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11299620 104009254 CHEMBL269004 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041690 CCCN[C@H]1CCc2cccc(CS(=O)(=O)C(F)(F)F)c2C1 InChI=1S/C15H20F3NO2S/c1-2-8-19-13-7-6-11-4-3-5-12(14(11)9-13)10-22(20,21)15(16,17)18/h3-5,13,19H,2,6-10H2,1H3/t13-/m0/s1 YLLMKDPCGLJFQN-ZDUSSCGKSA-N 50407734 CHEMBL2021524 D(2) dopamine receptor Homo sapiens >413 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70683414 163356758 CHEMBL2021524 ZINC84500346 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041691 CCCN[C@H]1CCc2cccc(CS(=O)(=O)C(F)(F)F)c2C1 InChI=1S/C15H20F3NO2S/c1-2-8-19-13-7-6-11-4-3-5-12(14(11)9-13)10-22(20,21)15(16,17)18/h3-5,13,19H,2,6-10H2,1H3/t13-/m0/s1 YLLMKDPCGLJFQN-ZDUSSCGKSA-N 50407734 CHEMBL2021524 D(2) dopamine receptor Homo sapiens 225 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70683414 163356758 CHEMBL2021524 ZINC84500346 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041692 CCCN[C@H]1CCc2c(CS(=O)(=O)C(F)(F)F)cccc2C1 InChI=1S/C15H20F3NO2S/c1-2-8-19-13-6-7-14-11(9-13)4-3-5-12(14)10-22(20,21)15(16,17)18/h3-5,13,19H,2,6-10H2,1H3/t13-/m0/s1 NNGXRRFVMCSLCM-ZDUSSCGKSA-N 50407737 CHEMBL2021538 D(2) dopamine receptor Homo sapiens 8.7 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70681318 163356761 CHEMBL2021538 ZINC84615540 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041693 CCCN[C@@H]1CCc2cccc(CS(=O)(=O)C(F)(F)F)c2C1 InChI=1S/C15H20F3NO2S/c1-2-8-19-13-7-6-11-4-3-5-12(14(11)9-13)10-22(20,21)15(16,17)18/h3-5,13,19H,2,6-10H2,1H3/t13-/m1/s1 YLLMKDPCGLJFQN-CYBMUJFWSA-N 50407735 CHEMBL2021539 D(2) dopamine receptor Homo sapiens 69 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70691866 163356759 CHEMBL2021539 ZINC84596176 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041697 CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 InChI=1S/C14H18F3NO3S/c1-2-8-18-11-7-6-10-4-3-5-13(12(10)9-11)21-22(19,20)14(15,16)17/h3-5,11,18H,2,6-9H2,1H3 ZRWGXXAMGVLDQT-UHFFFAOYSA-N 50034368 CHEMBL28313::Trifluoro-methanesulfonic acid 7-propylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester D(2) dopamine receptor Homo sapiens 108 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14977566 103942569 CHEMBL28313 ZINC36187757 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041699 CCCN(CCC)C1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 InChI=1S/C17H24F3NO3S/c1-3-10-21(11-4-2)14-9-8-13-6-5-7-16(15(13)12-14)24-25(22,23)17(18,19)20/h5-7,14H,3-4,8-12H2,1-2H3 YEEMKPJFAQAHOW-UHFFFAOYSA-N 50034366 CHEMBL28437::Trifluoro-methanesulfonic acid 7-dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester D(2) dopamine receptor Homo sapiens 62 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14973078 103942567 CHEMBL28437 ZINC36187760 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041700 CCCN[C@@H]1CCc2cccc(CS(=O)(=O)C(F)(F)F)c2C1 InChI=1S/C15H20F3NO2S/c1-2-8-19-13-7-6-11-4-3-5-12(14(11)9-13)10-22(20,21)15(16,17)18/h3-5,13,19H,2,6-10H2,1H3/t13-/m1/s1 YLLMKDPCGLJFQN-CYBMUJFWSA-N 50407735 CHEMBL2021539 D(2) dopamine receptor Homo sapiens 311 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70691866 163356759 CHEMBL2021539 ZINC84596176 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041702 CCCN[C@H]1CCc2c(CS(=O)(=O)C(F)(F)F)cccc2C1 InChI=1S/C15H20F3NO2S/c1-2-8-19-13-6-7-14-11(9-13)4-3-5-12(14)10-22(20,21)15(16,17)18/h3-5,13,19H,2,6-10H2,1H3/t13-/m0/s1 NNGXRRFVMCSLCM-ZDUSSCGKSA-N 50407737 CHEMBL2021538 D(2) dopamine receptor Homo sapiens 115 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70681318 163356761 CHEMBL2021538 ZINC84615540 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041711 CCCN[C@@H]1CCc2c(CS(=O)(=O)C(F)(F)F)cccc2C1 InChI=1S/C15H20F3NO2S/c1-2-8-19-13-6-7-14-11(9-13)4-3-5-12(14)10-22(20,21)15(16,17)18/h3-5,13,19H,2,6-10H2,1H3/t13-/m1/s1 NNGXRRFVMCSLCM-CYBMUJFWSA-N 50407736 CHEMBL2021525 D(2) dopamine receptor Homo sapiens >3800 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407736&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70691861 163356760 CHEMBL2021525 ZINC84635039 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50041713 CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m1/s1 ASXGJMSKWNBENU-CQSZACIVSA-N 50016777 ((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium::(8-Hydroxyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol ((R)-OH-DPAT)::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol(8-OH-DPAT)::CHEMBL26998::R-(+)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol D(2) dopamine receptor Homo sapiens 90 ChEMBL 10.1021/jm00008a010 10.7270/Q24F1RD6 7731017 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603866 103928146 73364 CHEMBL26998 ZINC03870312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044144 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 1.9 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044145 N[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C10H12FN/c11-10-3-1-2-7-6-8(12)4-5-9(7)10/h1-3,8H,4-6,12H2/t8-/m1/s1 VCSRUJJOQUHUJC-MRVPVSSYSA-N 50054334 (R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamine::CHEMBL138792 D(2) dopamine receptor Homo sapiens 864 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10725712 103950984 CHEMBL138792 ZINC08699656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044146 CC(C)N[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C13H18FN/c1-9(2)15-11-6-7-12-10(8-11)4-3-5-13(12)14/h3-5,9,11,15H,6-8H2,1-2H3/t11-/m1/s1 PEALWHNJZNZNMZ-LLVKDONJSA-N 50054340 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-isopropyl-amine::CHEMBL342630 D(2) dopamine receptor Homo sapiens 5940 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10608413 103950990 CHEMBL342630 ZINC13760019 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044147 CCCN[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C13H18FN/c1-2-8-15-11-6-7-12-10(9-11)4-3-5-13(12)14/h3-5,11,15H,2,6-9H2,1H3/t11-/m1/s1 PAFOMDPWWHFCGE-LLVKDONJSA-N 50054336 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL139345 D(2) dopamine receptor Homo sapiens 582 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10679847 103950986 CHEMBL139345 ZINC13760018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044148 CCCN(CCC)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C16H24FN/c1-3-10-18(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)17/h5-7,14H,3-4,8-12H2,1-2H3/t14-/m1/s1 WFENTJXFRAVXHY-CQSZACIVSA-N 50053670 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine; hydrochloride::CHEMBL541858::CHEMBL69985 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10729313 103950349 CHEMBL69985CHEMBL541858 ZINC13759323 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044149 Fc1cccc2C[C@@H](CCc12)NCCCCN1C(=O)CC2(CCCC2)CC1=O InChI=1S/C23H31FN2O2/c24-20-7-5-6-17-14-18(8-9-19(17)20)25-12-3-4-13-26-21(27)15-23(16-22(26)28)10-1-2-11-23/h5-7,18,25H,1-4,8-16H2/t18-/m1/s1 GVWRDZDVMQQZBK-GOSISDBHSA-N 50054333 8-[4-((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL139089 D(2) dopamine receptor Homo sapiens 68 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620194 103950983 CHEMBL139089 ZINC12356266 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044151 CCCN(C(C)C)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C16H24FN/c1-4-10-18(12(2)3)14-8-9-15-13(11-14)6-5-7-16(15)17/h5-7,12,14H,4,8-11H2,1-3H3/t14-/m1/s1 LHEQMLMJFATZEM-CQSZACIVSA-N 50054335 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-isopropyl-propyl-amine::CHEMBL345087 D(2) dopamine receptor Homo sapiens 4720 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10586728 103950985 CHEMBL345087 ZINC13760021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044152 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.160000 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044153 Fc1cccc2C[C@@H](CCc12)NCc1ccccc1 InChI=1S/C17H18FN/c18-17-8-4-7-14-11-15(9-10-16(14)17)19-12-13-5-2-1-3-6-13/h1-8,15,19H,9-12H2/t15-/m1/s1 QBTYVNHGXHWAKS-OAHLLOKOSA-N 50054339 Benzyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine::CHEMBL141537 D(2) dopamine receptor Homo sapiens 779 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10515180 103950989 CHEMBL141537 ZINC12355962 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044154 CCCCN[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C14H20FN/c1-2-3-9-16-12-7-8-13-11(10-12)5-4-6-14(13)15/h4-6,12,16H,2-3,7-10H2,1H3/t12-/m1/s1 VXPJDPSEYZZZEM-GFCCVEGCSA-N 50054341 Butyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine::CHEMBL141511 D(2) dopamine receptor Homo sapiens 254 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10560954 103950991 CHEMBL141511 ZINC13760020 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044155 CCCCN(CCC)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C17H26FN/c1-3-5-12-19(11-4-2)15-9-10-16-14(13-15)7-6-8-17(16)18/h6-8,15H,3-5,9-13H2,1-2H3/t15-/m1/s1 VYCKVQISRHCOOL-OAHLLOKOSA-N 50054338 Butyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL141510 D(2) dopamine receptor Homo sapiens 46 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10355406 103950988 CHEMBL141510 ZINC13760022 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044156 CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C26H37FN2O2/c1-2-14-28(21-10-11-22-20(17-21)8-7-9-23(22)27)15-5-6-16-29-24(30)18-26(19-25(29)31)12-3-4-13-26/h7-9,21H,2-6,10-19H2,1H3/t21-/m1/s1 BYVRVQNZFICZEB-OAQYLSRUSA-N 50054342 8-{4-[((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL138998 D(2) dopamine receptor Homo sapiens 17 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10502670 103950992 CHEMBL138998 ZINC13760023 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50044157 CCCN(Cc1ccccc1)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C20H24FN/c1-2-13-22(15-16-7-4-3-5-8-16)18-11-12-19-17(14-18)9-6-10-20(19)21/h3-10,18H,2,11-15H2,1H3/t18-/m1/s1 IZRKKTGXKLIJDE-GOSISDBHSA-N 50054337 Benzyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL65847 D(2) dopamine receptor Homo sapiens 179 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402380 103950987 CHEMBL65847 ZINC13760017 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50047766 COc1cc(F)ccc1N1CCN(CCCNc2ncccc2C(=O)N(C)C)CC1 InChI=1S/C22H30FN5O2/c1-26(2)22(29)18-6-4-9-24-21(18)25-10-5-11-27-12-14-28(15-13-27)19-8-7-17(23)16-20(19)30-3/h4,6-9,16H,5,10-15H2,1-3H3,(H,24,25) ONPBIKNDHFIIGZ-UHFFFAOYSA-N 50408236 CHEMBL420620 D(2) dopamine receptor Homo sapiens 6700 ChEMBL 10.1021/jm970166j 10.7270/Q2R78GD2 9276013 Elworthy, TR; Ford, AP; Bantle, GW; Morgans, DJ; Ozer, RS; Palmer, WS; Repke, DB; Romero, M; Sandoval, L; Sjogren, EB; Talamas, FX; Vazquez, A; Wu, H; Arredondo, NF; Blue, DR; DeSousa, A; Gross, LM; Kava, MS; Lesnick, JD; Vimont, RL; Williams, TJ; Zhu, QM; Pfister, JR; Clarke, DE Roche Bioscience http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408236&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10621790 163357260 CHEMBL420620 ZINC13764559 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50047772 COc1cc(F)ccc1N1CCN(CCCNc2c(cnc3n(C)nc(C)c23)C(=O)N(C)C)CC1 InChI=1S/C25H34FN7O2/c1-17-22-23(19(25(34)30(2)3)16-28-24(22)31(4)29-17)27-9-6-10-32-11-13-33(14-12-32)20-8-7-18(26)15-21(20)35-5/h7-8,15-16H,6,9-14H2,1-5H3,(H,27,28) JEHYIUUKVDHKND-UHFFFAOYSA-N 50408197 CHEMBL91605 D(2) dopamine receptor Homo sapiens 6400 ChEMBL 10.1021/jm970166j 10.7270/Q2R78GD2 9276013 Elworthy, TR; Ford, AP; Bantle, GW; Morgans, DJ; Ozer, RS; Palmer, WS; Repke, DB; Romero, M; Sandoval, L; Sjogren, EB; Talamas, FX; Vazquez, A; Wu, H; Arredondo, NF; Blue, DR; DeSousa, A; Gross, LM; Kava, MS; Lesnick, JD; Vimont, RL; Williams, TJ; Zhu, QM; Pfister, JR; Clarke, DE Roche Bioscience http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10624682 163357221 CHEMBL91605 ZINC13764600 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50047780 COc1ccccc1N1CCN(CCCNc2ncccc2C(=O)N(C)C)CC1 InChI=1S/C22H31N5O2/c1-25(2)22(28)18-8-6-11-23-21(18)24-12-7-13-26-14-16-27(17-15-26)19-9-4-5-10-20(19)29-3/h4-6,8-11H,7,12-17H2,1-3H3,(H,23,24) MNIPVWNHCWNYRB-UHFFFAOYSA-N 50408229 CHEMBL329160 D(2) dopamine receptor Homo sapiens 7400 ChEMBL 10.1021/jm970166j 10.7270/Q2R78GD2 9276013 Elworthy, TR; Ford, AP; Bantle, GW; Morgans, DJ; Ozer, RS; Palmer, WS; Repke, DB; Romero, M; Sandoval, L; Sjogren, EB; Talamas, FX; Vazquez, A; Wu, H; Arredondo, NF; Blue, DR; DeSousa, A; Gross, LM; Kava, MS; Lesnick, JD; Vimont, RL; Williams, TJ; Zhu, QM; Pfister, JR; Clarke, DE Roche Bioscience http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408229&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865577 163357253 CHEMBL329160 ZINC26648473 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50047781 COc1ccccc1N1CCN(CCCNc2cc(C)ccc2C(=O)N(C)C)CC1 InChI=1S/C24H34N4O2/c1-19-10-11-20(24(29)26(2)3)21(18-19)25-12-7-13-27-14-16-28(17-15-27)22-8-5-6-9-23(22)30-4/h5-6,8-11,18,25H,7,12-17H2,1-4H3 RCDCEIAISULOCZ-UHFFFAOYSA-N 50408241 CHEMBL89030 D(2) dopamine receptor Homo sapiens 7300 ChEMBL 10.1021/jm970166j 10.7270/Q2R78GD2 9276013 Elworthy, TR; Ford, AP; Bantle, GW; Morgans, DJ; Ozer, RS; Palmer, WS; Repke, DB; Romero, M; Sandoval, L; Sjogren, EB; Talamas, FX; Vazquez, A; Wu, H; Arredondo, NF; Blue, DR; DeSousa, A; Gross, LM; Kava, MS; Lesnick, JD; Vimont, RL; Williams, TJ; Zhu, QM; Pfister, JR; Clarke, DE Roche Bioscience http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323795 163357265 CHEMBL89030 ZINC26578785 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50047782 CN(C)C(=O)c1cnc2n(C)nc(C)c2c1NCCCN1CCN(CC1)c1ccccc1OCC(F)(F)F InChI=1S/C26H34F3N7O2/c1-18-22-23(19(25(37)33(2)3)16-31-24(22)34(4)32-18)30-10-7-11-35-12-14-36(15-13-35)20-8-5-6-9-21(20)38-17-26(27,28)29/h5-6,8-9,16H,7,10-15,17H2,1-4H3,(H,30,31) BSUZYOKJXFBXNY-UHFFFAOYSA-N 50408199 CHEMBL88160 D(2) dopamine receptor Homo sapiens 8100 ChEMBL 10.1021/jm970166j 10.7270/Q2R78GD2 9276013 Elworthy, TR; Ford, AP; Bantle, GW; Morgans, DJ; Ozer, RS; Palmer, WS; Repke, DB; Romero, M; Sandoval, L; Sjogren, EB; Talamas, FX; Vazquez, A; Wu, H; Arredondo, NF; Blue, DR; DeSousa, A; Gross, LM; Kava, MS; Lesnick, JD; Vimont, RL; Williams, TJ; Zhu, QM; Pfister, JR; Clarke, DE Roche Bioscience http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9893282 163357223 CHEMBL88160 ZINC13764597 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50045741 CCCN(CCC)[C@@H]1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2[C@@H]1C InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)15-10-9-14-7-6-8-16(17(14)13(15)3)25-26(23,24)18(19,20)21/h6-8,13,15H,4-5,9-12H2,1-3H3/t13-,15-/m1/s1 KCQJHHZOOWJYBY-UKRRQHHQSA-N 50030405 CHEMBL290546::Trifluoro-methanesulfonic acid (7R,8S)-7-dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-yl ester D(2) dopamine receptor Homo sapiens 124 ChEMBL 10.1021/jm00001a020 10.7270/Q2W09505 7530773 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030405&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10385897 103939302 CHEMBL290546 ZINC36187776 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50045743 CCCN(CCC)[C@@H]1CCc2cccc(OC)c2[C@@H]1C InChI=1S/C18H29NO/c1-5-12-19(13-6-2)16-11-10-15-8-7-9-17(20-4)18(15)14(16)3/h7-9,14,16H,5-6,10-13H2,1-4H3/t14-,16-/m1/s1 HVMJOCQDRCRUSG-GDBMZVCRSA-N 50030406 ((1S,2R)-8-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL290446 D(2) dopamine receptor Homo sapiens 33.9 ChEMBL 10.1021/jm00001a020 10.7270/Q2W09505 7530773 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030406&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18652674 103939303 CHEMBL290446 ZINC13740168 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50045744 CCCN(CCC)[C@H]1CCc2cccc(OC)c2[C@H]1C InChI=1S/C18H29NO/c1-5-12-19(13-6-2)16-11-10-15-8-7-9-17(20-4)18(15)14(16)3/h7-9,14,16H,5-6,10-13H2,1-4H3/t14-,16-/m0/s1 HVMJOCQDRCRUSG-HOCLYGCPSA-N 50030407 ((1R,2S)-8-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL287770 D(2) dopamine receptor Homo sapiens 1050 ChEMBL 10.1021/jm00001a020 10.7270/Q2W09505 7530773 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030407&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13869506 103939304 CHEMBL287770 ZINC13740169 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50045745 CCCN(CCC)[C@@H]1CCc2ccccc2[C@@H]1C InChI=1S/C17H27N/c1-4-12-18(13-5-2)17-11-10-15-8-6-7-9-16(15)14(17)3/h6-9,14,17H,4-5,10-13H2,1-3H3/t14-,17+/m0/s1 BSFUDLSQCLQWQE-WMLDXEAASA-N 50030409 ((1S,2R)-1-Methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL41802 D(2) dopamine receptor Homo sapiens 87 ChEMBL 10.1021/jm00001a020 10.7270/Q2W09505 7530773 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030409&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992102 103939306 CHEMBL41802 ZINC13740184 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50045752 CCCN(CCC)[C@@H]1CCc2cccc(C(=O)OC)c2[C@@H]1C InChI=1S/C19H29NO2/c1-5-12-20(13-6-2)17-11-10-15-8-7-9-16(19(21)22-4)18(15)14(17)3/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17-/m1/s1 ZXWIDAPGUOZUDB-RHSMWYFYSA-N 50030412 (7R,8S)-7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester::CHEMBL40634 D(2) dopamine receptor Homo sapiens 58.8 ChEMBL 10.1021/jm00001a020 10.7270/Q2W09505 7530773 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030412&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11722531 103939309 CHEMBL40634 ZINC13740180 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50045757 CCCN(CCC)[C@@H]1CCc2cccc(O)c2[C@@H]1C InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-16(19)17(14)13(15)3/h6-8,13,15,19H,4-5,9-12H2,1-3H3/t13-,15-/m1/s1 ZNLWDIZBTNNEHH-UKRRQHHQSA-N 50011261 (+)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride::(-)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride::7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride::CHEMBL43475::CHEMBL544757 D(2) dopamine receptor Homo sapiens 30 ChEMBL 10.1021/jm00001a020 10.7270/Q2W09505 7530773 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011261&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3085297 103923896 CHEMBL43475CHEMBL544757 ZINC13740186 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50045766 CCCN(C(C)C)[C@@H]1CCc2cccc(O)c2[C@@H]1C InChI=1S/C17H27NO/c1-5-11-18(12(2)3)15-10-9-14-7-6-8-16(19)17(14)13(15)4/h6-8,12-13,15,19H,5,9-11H2,1-4H3/t13-,15-/m1/s1 QGAQMNABIHSUAU-UKRRQHHQSA-N 50030411 (7R,8S)-7-(Isopropyl-propyl-amino)-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL288721 D(2) dopamine receptor Homo sapiens 614 ChEMBL 10.1021/jm00001a020 10.7270/Q2W09505 7530773 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030411&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11777449 103939308 CHEMBL288721 ZINC13740172 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50045770 CCCN(CCC)[C@@H]1CCc2cccc(C(C)=O)c2[C@@H]1C InChI=1S/C19H29NO/c1-5-12-20(13-6-2)18-11-10-16-8-7-9-17(15(4)21)19(16)14(18)3/h7-9,14,18H,5-6,10-13H2,1-4H3/t14-,18-/m1/s1 XNWAWODVOOTTKE-RDTXWAMCSA-N 50030418 1-((7R,8S)-7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-yl)-ethanone::CHEMBL290091 D(2) dopamine receptor Homo sapiens 40 ChEMBL 10.1021/jm00001a020 10.7270/Q2W09505 7530773 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9994243 103939315 CHEMBL290091 ZINC13740178 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50047499 O\C(=C/C(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H22ClNO2/c22-19-8-6-17(7-9-19)20(24)14-21(25)18-10-12-23(13-11-18)15-16-4-2-1-3-5-16/h1-9,14,18,24H,10-13,15H2/b20-14- IALFUNSVFHBTHD-ZHZULCJRSA-N 50454602 CHEMBL2112285 D(2) dopamine receptor Homo sapiens 120 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618211 225146271 CHEMBL2112285 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50047500 CC1(CCN(Cc2ccccc2)CC1)C(=O)\C=C(/O)c1ccc(Cl)cc1 InChI=1S/C22H24ClNO2/c1-22(21(26)15-20(25)18-7-9-19(23)10-8-18)11-13-24(14-12-22)16-17-5-3-2-4-6-17/h2-10,15,25H,11-14,16H2,1H3/b20-15- FSHKWBYMYDCHAB-HKWRFOASSA-N 50454603 CHEMBL2112284 D(2) dopamine receptor Homo sapiens 410 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454603&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714184 225146272 CHEMBL2112284 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50053286 COc1ccccc1N1CCN(C[C@H]2CN=C3N2C(SC)=Nc2ccccc32)CC1 InChI=1S/C23H27N5OS/c1-29-21-10-6-5-9-20(21)27-13-11-26(12-14-27)16-17-15-24-22-18-7-3-4-8-19(18)25-23(30-2)28(17)22/h3-10,17H,11-16H2,1-2H3/t17-/m1/s1 DVYBIZHLZSDANU-QGZVFWFLSA-N 50369382 CHEMBL1788223 D(2) dopamine receptor Homo sapiens 449 ChEMBL 10.1021/jm970159v 10.7270/Q2GM880H 9703460 Chern, JW; Tao, PL; Wang, KC; Gutcait, A; Liu, SW; Yen, MH; Chien, SL; Rong, JK National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9931977 160848484 CHEMBL1788223 ZINC40784711 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50053297 COc1ccccc1N1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C21H24N4O3/c1-28-19-9-5-4-8-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-6-2-3-7-17(16)22-21(25)27/h2-9H,10-15H2,1H3,(H,22,27) ZFDWAPWETDMDSZ-UHFFFAOYSA-N 50040253 3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1H-quinazoline-2,4-dione::CHEMBL51433 D(2) dopamine receptor Homo sapiens 132 ChEMBL 10.1021/jm970159v 10.7270/Q2GM880H 9703460 Chern, JW; Tao, PL; Wang, KC; Gutcait, A; Liu, SW; Yen, MH; Chien, SL; Rong, JK National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122065 103972313 CHEMBL51433 ZINC05115799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50053298 COc1ccccc1N1CCN(CC2CN=C3N2C(=O)Nc2ccccc32)CC1 InChI=1S/C22H25N5O2/c1-29-20-9-5-4-8-19(20)26-12-10-25(11-13-26)15-16-14-23-21-17-6-2-3-7-18(17)24-22(28)27(16)21/h2-9,16H,10-15H2,1H3,(H,24,28) FUCGAUZSWYLMRK-UHFFFAOYSA-N 50066109 3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-dihydro-3H-imidazo[1,2-c]quinazolin-5-one::CHEMBL106737 D(2) dopamine receptor Homo sapiens 239 ChEMBL 10.1021/jm970159v 10.7270/Q2GM880H 9703460 Chern, JW; Tao, PL; Wang, KC; Gutcait, A; Liu, SW; Yen, MH; Chien, SL; Rong, JK National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066109&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487531 103960791 CHEMBL106737 ZINC26840261 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50049440 CCCN(CCC)C1CCc2nc(OC)ccc2C1 InChI=1S/C16H26N2O/c1-4-10-18(11-5-2)14-7-8-15-13(12-14)6-9-16(17-15)19-3/h6,9,14H,4-5,7-8,10-12H2,1-3H3 CQPLSAHLVMGWEI-UHFFFAOYSA-N 50032640 (2-Methoxy-5,6,7,8-tetrahydro-quinolin-6-yl)-dipropyl-amine::CHEMBL105509 D(2) dopamine receptor Homo sapiens 1202 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992903 103941095 CHEMBL105509 ZINC13742650 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50049449 CCCN(CCC)C1CCc2nc(OC)ccc2C1 InChI=1S/C16H26N2O/c1-4-10-18(11-5-2)14-7-8-15-13(12-14)6-9-16(17-15)19-3/h6,9,14H,4-5,7-8,10-12H2,1-3H3 CQPLSAHLVMGWEI-UHFFFAOYSA-N 50032640 (2-Methoxy-5,6,7,8-tetrahydro-quinolin-6-yl)-dipropyl-amine::CHEMBL105509 D(2) dopamine receptor Homo sapiens >3333 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992903 103941095 CHEMBL105509 ZINC13742650 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50049453 CCCN(CCC)C1CCc2nc(N)sc2C1 InChI=1S/C13H23N3S/c1-3-7-16(8-4-2)10-5-6-11-12(9-10)17-13(14)15-11/h10H,3-9H2,1-2H3,(H2,14,15) ABRFKTAFRQVZBR-UHFFFAOYSA-N 50032643 CHEMBL105512::N*6*,N*6*-Dipropyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine D(2) dopamine receptor Homo sapiens 462.0 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13670706 103941098 CHEMBL105512 ZINC13742644 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50049454 CCCN(CCC)C1CCc2[nH]ncc2C1 InChI=1S/C13H23N3/c1-3-7-16(8-4-2)12-5-6-13-11(9-12)10-14-15-13/h10,12H,3-9H2,1-2H3,(H,14,15) GLKCCTUKWPNZKT-UHFFFAOYSA-N 50032642 CHEMBL318740::Dipropyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine D(2) dopamine receptor Homo sapiens >3333 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12898419 103941097 CHEMBL318740 ZINC13742646 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50049455 CCCN(CCC)C1CCc2nc(N)ccc2C1 InChI=1S/C15H25N3/c1-3-9-18(10-4-2)13-6-7-14-12(11-13)5-8-15(16)17-14/h5,8,13H,3-4,6-7,9-11H2,1-2H3,(H2,16,17) QDXLLGQCGFUDMI-UHFFFAOYSA-N 50032644 CHEMBL110888::N*6*,N*6*-Dipropyl-5,6,7,8-tetrahydro-quinoline-2,6-diamine D(2) dopamine receptor Homo sapiens 5 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992189 103941099 CHEMBL110888 ZINC13742652 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50049457 CCCN(CCC)C1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3 MDBWEQVKJDMEMK-UHFFFAOYSA-N 50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172267 103931135 CHEMBL273273 128 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50049458 CCCN(CCC)C1CCc2nc(N)ccc2C1 InChI=1S/C15H25N3/c1-3-9-18(10-4-2)13-6-7-14-12(11-13)5-8-15(16)17-14/h5,8,13H,3-4,6-7,9-11H2,1-2H3,(H2,16,17) QDXLLGQCGFUDMI-UHFFFAOYSA-N 50032644 CHEMBL110888::N*6*,N*6*-Dipropyl-5,6,7,8-tetrahydro-quinoline-2,6-diamine D(2) dopamine receptor Homo sapiens 17 ChEMBL 10.1021/jm00016a016 10.7270/Q28W3C9S 7636875 Glase, SA; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992189 103941099 CHEMBL110888 ZINC13742652 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056783 O[C@@H](CCCN1CCN(CC1)c1ccccn1)c1ccc(F)cc1 InChI=1S/C19H24FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10,18,24H,3-4,11-15H2/t18-/m0/s1 LVXYAFNPMXCRJI-SFHVURJKSA-N 50036732 (S)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-ol::CHEMBL339963 D(2) dopamine receptor Homo sapiens 101 ChEMBL 10.1021/jm00076a022 10.7270/Q2C828CS 7902870 Jaen, JC; Caprathe, BW; Pugsley, TA; Wise, LD; Akunne, H Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036732&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44350942 103944373 CHEMBL339963 ZINC27306745 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056786 O[C@@H](CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2/t17-/m0/s1 ZXUYYZPJUGQHLQ-KRWDZBQOSA-N 50036736 (S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::CHEMBL129263 D(2) dopamine receptor Homo sapiens 3346.0 ChEMBL 10.1021/jm00076a022 10.7270/Q2C828CS 7902870 Jaen, JC; Caprathe, BW; Pugsley, TA; Wise, LD; Akunne, H Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036736&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020651 103944377 CHEMBL129263 ZINC00013635 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056796 O[C@H](CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2/t17-/m1/s1 ZXUYYZPJUGQHLQ-QGZVFWFLSA-N 50036737 (R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::CHEMBL129768 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1021/jm00076a022 10.7270/Q2C828CS 7902870 Jaen, JC; Caprathe, BW; Pugsley, TA; Wise, LD; Akunne, H Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604868 103944378 CHEMBL129768 ZINC03995923 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056799 O[C@H](CCCN1CCN(CC1)c1ccccn1)c1ccc(F)cc1 InChI=1S/C19H24FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10,18,24H,3-4,11-15H2/t18-/m1/s1 LVXYAFNPMXCRJI-GOSISDBHSA-N 50036735 (R)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-ol::CHEMBL339033 D(2) dopamine receptor Homo sapiens 403.0 ChEMBL 10.1021/jm00076a022 10.7270/Q2C828CS 7902870 Jaen, JC; Caprathe, BW; Pugsley, TA; Wise, LD; Akunne, H Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44350991 103944376 CHEMBL339033 ZINC13834243 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056800 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.440000 ChEMBL 10.1021/jm00076a022 10.7270/Q2C828CS 7902870 Jaen, JC; Caprathe, BW; Pugsley, TA; Wise, LD; Akunne, H Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056801 O[C@@H](CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2/t20-/m0/s1 WNZBBTJFOIOEMP-FQEVSTJZSA-N 50036734 (S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol::CHEMBL129237 D(2) dopamine receptor Homo sapiens 73 ChEMBL 10.1021/jm00076a022 10.7270/Q2C828CS 7902870 Jaen, JC; Caprathe, BW; Pugsley, TA; Wise, LD; Akunne, H Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16048564 103944375 CHEMBL129237 ZINC02516030 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056803 O[C@H](CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2/t20-/m1/s1 WNZBBTJFOIOEMP-HXUWFJFHSA-N 50036738 (R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol::CHEMBL129159 D(2) dopamine receptor Homo sapiens 279 ChEMBL 10.1021/jm00076a022 10.7270/Q2C828CS 7902870 Jaen, JC; Caprathe, BW; Pugsley, TA; Wise, LD; Akunne, H Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24867245 103944379 CHEMBL129159 ZINC04257980 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056806 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ccccn1 InChI=1S/C19H22FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10H,3-4,11-15H2 XTKDAFGWCDAMPY-UHFFFAOYSA-N 50036733 1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one(Azaperone)::Azaperone::CHEMBL340211 D(2) dopamine receptor Homo sapiens 52 ChEMBL 10.1021/jm00076a022 10.7270/Q2C828CS 7902870 Jaen, JC; Caprathe, BW; Pugsley, TA; Wise, LD; Akunne, H Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036733&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15443 103944374 CHEMBL340211 ZINC19632933 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50055867 COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 InChI=1S/C23H33N5O/c1-29-22-6-3-2-5-21(22)28-17-15-27(16-18-28)14-11-19-7-9-20(10-8-19)26-23-24-12-4-13-25-23/h2-6,12-13,19-20H,7-11,14-18H2,1H3,(H,24,25,26)/t19-,20- HWSOAPGUROKPOX-MXVIHJGJSA-N 50063281 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine::CHEMBL164792 D(2) dopamine receptor Homo sapiens 9.9 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795011 103958612 CHEMBL164792 ZINC13778698 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50055870 C1CC(CCC1Nc1ncccn1)N1CCN(CC1)c1ccccc1 InChI=1S/C20H27N5/c1-2-5-18(6-3-1)24-13-15-25(16-14-24)19-9-7-17(8-10-19)23-20-21-11-4-12-22-20/h1-6,11-12,17,19H,7-10,13-16H2,(H,21,22,23) WEVXDKFRXWZSDU-UHFFFAOYSA-N 50063282 CHEMBL2110308::{4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 320 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497177 103958613 CHEMBL2110308 ZINC00601779 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50055871 Fc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 InChI=1S/C22H30FN5/c23-19-4-8-21(9-5-19)28-16-14-27(15-17-28)13-10-18-2-6-20(7-3-18)26-22-24-11-1-12-25-22/h1,4-5,8-9,11-12,18,20H,2-3,6-7,10,13-17H2,(H,24,25,26)/t18-,20- FANDJZBJYJYKGY-KESTWPANSA-N 50063277 (4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine::CHEMBL349034 D(2) dopamine receptor Homo sapiens 79 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10738750 103958608 CHEMBL349034 ZINC13778704 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50055872 C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C21H30N6/c1-2-10-22-20(4-1)27-16-14-26(15-17-27)13-9-18-5-7-19(8-6-18)25-21-23-11-3-12-24-21/h1-4,10-12,18-19H,5-9,13-17H2,(H,23,24,25)/t18-,19- YKCHNWKXANLFGS-WGSAOQKQSA-N 50063280 CHEMBL355371::{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522950 103958611 CHEMBL355371 ZINC13778706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50055873 C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20- OUUMPVSFLSOGJZ-MXVIHJGJSA-N 50063296 CHEMBL165679::{4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 5.2 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3075615 103958627 CHEMBL165679 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50055880 C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@H](CC1)Nc1ncccn1 InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20+ OUUMPVSFLSOGJZ-BGYRXZFFSA-N 50455438 CHEMBL3084971 D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3075615 225146447 CHEMBL3084971 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056155 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 41.9 ChEMBL 10.1021/jm00004a011 10.7270/Q2HX1BQH 7861413 Hedberg, MH; Johansson, AM; Nordvall, G; Yliniemela, A; Li, HB; Martin, AR; Hjorth, S; Unelius, L; Sundell, S; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056162 CN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1 YGOZTDLAUVOPMF-OAHLLOKOSA-N 50036286 (R)-(-)-10-methyl-11-hydroxyaporphine::(R)-6,10-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL53510 D(2) dopamine receptor Homo sapiens 1070 ChEMBL 10.1021/jm00004a011 10.7270/Q2HX1BQH 7861413 Hedberg, MH; Johansson, AM; Nordvall, G; Yliniemela, A; Li, HB; Martin, AR; Hjorth, S; Unelius, L; Sundell, S; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3082625 103944104 CHEMBL53510 ZINC00006368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50056163 CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1 PCGXWSCASZVBJT-CQSZACIVSA-N 50016013 (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119455::R-(-)-11-hydroxy-aporphine D(2) dopamine receptor Homo sapiens 58.5 ChEMBL 10.1021/jm00004a011 10.7270/Q2HX1BQH 7861413 Hedberg, MH; Johansson, AM; Nordvall, G; Yliniemela, A; Li, HB; Martin, AR; Hjorth, S; Unelius, L; Sundell, S; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015045 103927694 CHEMBL119455 ZINC00002530 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50055137 NC1CCc2cc(O)c(O)cc2[C@H]1c1ccccc1 InChI=1S/C16H17NO2/c17-13-7-6-11-8-14(18)15(19)9-12(11)16(13)10-4-2-1-3-5-10/h1-5,8-9,13,16,18-19H,6-7,17H2/t13?,16-/m1/s1 RMBSJLJLHHNREK-FQNRMIAFSA-N 50035648 (R)-6-Amino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol::CHEMBL110362 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44339794 103943659 CHEMBL110362 ZINC26972710 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50058763 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.5 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50058783 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50060048 CCCN(C\C=C\I)C1COc2ccc(O)cc2C1 InChI=1S/C15H20INO2/c1-2-7-17(8-3-6-16)13-9-12-10-14(18)4-5-15(12)19-11-13/h3-6,10,13,18H,2,7-9,11H2,1H3/b6-3+ HDSARMPSJMIESZ-ZZXKWVIFSA-N 50038277 3-[((E)-3-Iodo-allyl)-propyl-amino]-chroman-6-ol::CHEMBL138015 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10090714 103945714 CHEMBL138015 ZINC13739888 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50060049 CCCN(C\C=C\I)C1CCc2c(O)cccc2C1 InChI=1S/C16H22INO/c1-2-10-18(11-4-9-17)14-7-8-15-13(12-14)5-3-6-16(15)19/h3-6,9,14,19H,2,7-8,10-12H2,1H3/b9-4+ LYFXQSOWXVVQIV-RUDMXATFSA-N 50038278 6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL263282 D(2) dopamine receptor Homo sapiens 324.0 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10451844 103945715 CHEMBL263282 ZINC13739884 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50060055 CCCN(C\C=C\I)C1CCc2ccc(O)cc2C1 InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+ RTMIJLQPWFKAFE-FPYGCLRLSA-N 50038276 (R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::7-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL110239 D(2) dopamine receptor Homo sapiens 265 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6305587 103945713 64137 CHEMBL110239 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50060061 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Homo sapiens 142 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50060069 CCCN(C\C=C\I)C1COc2c(O)cccc2C1 InChI=1S/C15H20INO2/c1-2-8-17(9-4-7-16)13-10-12-5-3-6-14(18)15(12)19-11-13/h3-7,13,18H,2,8-11H2,1H3/b7-4+ ONVPKPUWGYFERX-QPJJXVBHSA-N 50038279 3-[((E)-3-Iodo-allyl)-propyl-amino]-chroman-8-ol::CHEMBL133085 D(2) dopamine receptor Homo sapiens 784 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406989 103945716 CHEMBL133085 ZINC13739890 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50060074 CCCN(C\C=C\I)C1CCc2cc(O)ccc2C1 InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-14-12-16(19)7-5-13(14)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+ AQKFTLWWZGTUKW-FPYGCLRLSA-N 50038280 6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL336851 D(2) dopamine receptor Homo sapiens 9.7 ChEMBL 10.1021/jm00050a021 10.7270/Q2S46R0H 7990123 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9999267 103945717 CHEMBL336851 ZINC13739886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50060244 CN(C)C(=O)c1cccnc1NCCCN1CCN(CC1)c1ccccc1-c1ccccc1 InChI=1S/C27H33N5O/c1-30(2)27(33)24-13-8-15-28-26(24)29-16-9-17-31-18-20-32(21-19-31)25-14-7-6-12-23(25)22-10-4-3-5-11-22/h3-8,10-15H,9,16-21H2,1-2H3,(H,28,29) GUKVULLJWDLSGZ-UHFFFAOYSA-N 50408216 CHEMBL90746 D(2) dopamine receptor Homo sapiens 126 ChEMBL 10.1021/jm970166j 10.7270/Q2R78GD2 9276013 Elworthy, TR; Ford, AP; Bantle, GW; Morgans, DJ; Ozer, RS; Palmer, WS; Repke, DB; Romero, M; Sandoval, L; Sjogren, EB; Talamas, FX; Vazquez, A; Wu, H; Arredondo, NF; Blue, DR; DeSousa, A; Gross, LM; Kava, MS; Lesnick, JD; Vimont, RL; Williams, TJ; Zhu, QM; Pfister, JR; Clarke, DE Roche Bioscience http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408216&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10575254 163357240 CHEMBL90746 ZINC13764534 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50059507 Oc1cccc2C3CCN(CC=C)C3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040159 (Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10289 D(2) dopamine receptor Homo sapiens 75 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266636 103972219 CHEMBL10289 ZINC13826535 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50059514 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13-,14-/m1/s1 VRRJFCMGNMFNOE-ZIAGYGMSSA-N 50034330 (3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 D(2) dopamine receptor Homo sapiens 77.0 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 ZINC03790769 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50059518 COc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1 ZRAGXRIXRXDXCR-HIFRSBDPSA-N 50453387 CHEMBL566970 D(2) dopamine receptor Homo sapiens >339 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453387&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10060349 225145936 CHEMBL566970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50059526 CCCN1CCC2Cc3c(O)cccc3CC12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3 DYVLYWKEJHHXOH-UHFFFAOYSA-N 50455999 CHEMBL2114337 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18988835 225146915 CHEMBL2114337 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50059539 COc1cccc2CCC3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50455993 CHEMBL273412 D(2) dopamine receptor Homo sapiens 8.5 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18988817 225146909 CHEMBL273412 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50059542 Oc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14+/m1/s1 MHHLELSXRBTNRD-OCCSQVGLSA-N 50455996 CHEMBL566133 D(2) dopamine receptor Homo sapiens 59 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14944887 225146912 CHEMBL566133 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063058 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2C#N InChI=1S/C31H35N3O/c1-2-20-34(29-17-18-30-27(22-29)11-8-12-28(30)23-32)21-7-6-19-33-31(35)26-15-13-25(14-16-26)24-9-4-3-5-10-24/h3-5,8-16,29H,2,6-7,17-22H2,1H3,(H,33,35) ZQAMNGCYKZHATK-UHFFFAOYSA-N 50000025 CHEMBL416508 D(2) dopamine receptor Homo sapiens 100 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19592159 103914724 CHEMBL416508 ZINC13731274 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063059 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2C(N)=O InChI=1S/C31H37N3O2/c1-2-20-34(27-17-18-28-26(22-27)11-8-12-29(28)30(32)35)21-7-6-19-33-31(36)25-15-13-24(14-16-25)23-9-4-3-5-10-23/h3-5,8-16,27H,2,6-7,17-22H2,1H3,(H2,32,35)(H,33,36) LKZYQJSJNFLIIO-UHFFFAOYSA-N 50000026 CHEMBL59960 D(2) dopamine receptor Homo sapiens 631 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19592141 103914725 CHEMBL59960 ZINC01672949 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063060 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(Cl)cccc2C1 InChI=1S/C30H35ClN2O/c1-2-20-33(27-17-18-28-26(22-27)11-8-12-29(28)31)21-7-6-19-32-30(34)25-15-13-24(14-16-25)23-9-4-3-5-10-23/h3-5,8-16,27H,2,6-7,17-22H2,1H3,(H,32,34) KSCIAWWFBYAELA-UHFFFAOYSA-N 50000027 CHEMBL51977 D(2) dopamine receptor Homo sapiens 398 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9912796 103914726 CHEMBL51977 ZINC95548026 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063065 COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccc(cc2)C(C)=O)CC1 InChI=1S/C30H35N3O3/c1-23(34)24-9-11-25(12-10-24)26-13-15-27(16-14-26)30(35)31-17-5-6-18-32-19-21-33(22-20-32)28-7-3-4-8-29(28)36-2/h3-4,7-16H,5-6,17-22H2,1-2H3,(H,31,35) JARNORYOPMINDY-UHFFFAOYSA-N 50342717 4'-Acetyl-biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::4'-acetyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)biphenyl-4-carboxamide::CHEMBL294747 D(2) dopamine receptor Homo sapiens 40 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342717&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4302960 131345653 CHEMBL294747 ZINC03810247 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063066 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2ccccc2C1 InChI=1S/C30H36N2O/c1-2-21-32(29-19-18-25-12-6-7-13-28(25)23-29)22-9-8-20-31-30(33)27-16-14-26(15-17-27)24-10-4-3-5-11-24/h3-7,10-17,29H,2,8-9,18-23H2,1H3,(H,31,33) UJNGTNSLEZLHFI-UHFFFAOYSA-N 50000028 CHEMBL60713 D(2) dopamine receptor Homo sapiens 316 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19592133 103914727 CHEMBL60713 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063069 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2OS(C)(=O)=O InChI=1S/C31H38N2O4S/c1-3-21-33(28-18-19-29-27(23-28)12-9-13-30(29)37-38(2,35)36)22-8-7-20-32-31(34)26-16-14-25(15-17-26)24-10-5-4-6-11-24/h4-6,9-17,28H,3,7-8,18-23H2,1-2H3,(H,32,34) HYHZGIWTSKSXKP-UHFFFAOYSA-N 50000031 CHEMBL291801 D(2) dopamine receptor Homo sapiens 251 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10414769 103914730 CHEMBL291801 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063070 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(Br)cccc2C1 InChI=1S/C30H35BrN2O/c1-2-20-33(27-17-18-28-26(22-27)11-8-12-29(28)31)21-7-6-19-32-30(34)25-15-13-24(14-16-25)23-9-4-3-5-10-23/h3-5,8-16,27H,2,6-7,17-22H2,1H3,(H,32,34) HBJXUXOERUVVGH-UHFFFAOYSA-N 50000023 CHEMBL60038 D(2) dopamine receptor Homo sapiens 251 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000023&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19592126 103914722 CHEMBL60038 ZINC95547963 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063071 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2OS(=O)(=O)C(F)(F)F InChI=1S/C31H35F3N2O4S/c1-2-20-36(27-17-18-28-26(22-27)11-8-12-29(28)40-41(38,39)31(32,33)34)21-7-6-19-35-30(37)25-15-13-24(14-16-25)23-9-4-3-5-10-23/h3-5,8-16,27H,2,6-7,17-22H2,1H3,(H,35,37) ASINOPIKMGWLQS-UHFFFAOYSA-N 50000022 CHEMBL57219 D(2) dopamine receptor Homo sapiens 398 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000022&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10438351 103914721 CHEMBL57219 ZINC13731280 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063072 CN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C28H32N2O2/c1-30(25-16-17-26-24(20-25)10-7-11-27(26)31)19-6-5-18-29-28(32)23-14-12-22(13-15-23)21-8-3-2-4-9-21/h2-4,7-15,25,31H,5-6,16-20H2,1H3,(H,29,32) HFPUZJYAPWLJOL-UHFFFAOYSA-N 50000032 CHEMBL59642 D(2) dopamine receptor Homo sapiens 126 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19592119 103914731 1751 CHEMBL59642 ZINC01532215 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063073 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2OCC1CC1 InChI=1S/C34H42N2O2/c1-2-22-36(31-19-20-32-30(24-31)11-8-12-33(32)38-25-26-13-14-26)23-7-6-21-35-34(37)29-17-15-28(16-18-29)27-9-4-3-5-10-27/h3-5,8-12,15-18,26,31H,2,6-7,13-14,19-25H2,1H3,(H,35,37) UUKCJRIPKQWEID-UHFFFAOYSA-N 50000030 CHEMBL61444 D(2) dopamine receptor Homo sapiens 794 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10075078 103914729 CHEMBL61444 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063075 COc1cccc2CC(CCc12)N(C)CCCCNC(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C29H34N2O2/c1-31(26-17-18-27-25(21-26)11-8-12-28(27)33-2)20-7-6-19-30-29(32)24-15-13-23(14-16-24)22-9-4-3-5-10-22/h3-5,8-16,26H,6-7,17-21H2,1-2H3,(H,30,32) FOYUWODSNRINIS-UHFFFAOYSA-N 50000021 CHEMBL59554 D(2) dopamine receptor Homo sapiens 316 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19592101 103914720 CHEMBL59554 ZINC05848904 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063076 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2OC InChI=1S/C31H38N2O2/c1-3-21-33(28-18-19-29-27(23-28)12-9-13-30(29)35-2)22-8-7-20-32-31(34)26-16-14-25(15-17-26)24-10-5-4-6-11-24/h4-6,9-17,28H,3,7-8,18-23H2,1-2H3,(H,32,34) LVSUPYDDQCSHAN-UHFFFAOYSA-N 50000033 CHEMBL61717 D(2) dopamine receptor Homo sapiens 126 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19592121 103914732 CHEMBL61717 ZINC01673396 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063080 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C30H36N2O2/c1-2-20-32(27-17-18-28-26(22-27)11-8-12-29(28)33)21-7-6-19-31-30(34)25-15-13-24(14-16-25)23-9-4-3-5-10-23/h3-5,8-16,27,33H,2,6-7,17-22H2,1H3,(H,31,34) RISZOHTXHUANFZ-UHFFFAOYSA-N 50240560 Biphenyl-4-carboxylic acid {4-[(5-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-butyl}-amide::CHEMBL58669 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1016/S0960-894X(97)00350-8 10.7270/Q2R49S9S n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19592091 104098354 CHEMBL58669 ZINC29569216 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062239 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccccc12 InChI=1S/C18H20N4/c1-21-10-12-22(13-11-21)18-14-6-2-3-7-15(14)19-16-8-4-5-9-17(16)20-18/h2-9,19H,10-13H2,1H3 VQHITFFJBFOMBG-UHFFFAOYSA-N 50010591 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL73538 D(2) dopamine receptor Homo sapiens 2500 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search WEC 8E9X,8E9W 16103 103923366 CHEMBL73538 ZINC26377671 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062249 CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cc2ccccc12 InChI=1S/C20H21ClN2/c1-22-8-10-23(11-9-22)20-14-17-13-18(21)7-6-15(17)12-16-4-2-3-5-19(16)20/h2-7,13-14H,8-12H2,1H3 VYHUCPCVCHMNCC-UHFFFAOYSA-N 50028599 1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL275696 D(2) dopamine receptor Homo sapiens 520 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028599&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13014680 103937811 CHEMBL275696 ZINC13532244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062250 CC1c2ccccc2C=C(N2CCN(C)CC2)c2ccccc12 InChI=1S/C21H24N2/c1-16-18-8-4-3-7-17(18)15-21(20-10-6-5-9-19(16)20)23-13-11-22(2)12-14-23/h3-10,15-16H,11-14H2,1-2H3 NLYUVFZOJUSMNV-UHFFFAOYSA-N 50036438 1-Methyl-4-(5-methyl-5H-dibenzo[a,d]cyclohepten-10-yl)-piperazine::CHEMBL432762 D(2) dopamine receptor Homo sapiens 94 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323894 103944203 CHEMBL432762 ZINC13738218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062253 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 21 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062263 C\C=C1\c2ccccc2C=C(N2CCN(C)CC2)c2ccccc12 InChI=1S/C22H24N2/c1-3-18-19-9-5-4-8-17(19)16-22(21-11-7-6-10-20(18)21)24-14-12-23(2)13-15-24/h3-11,16H,12-15H2,1-2H3/b18-3- DISSGPVGANAWAA-ZUWFHJRGSA-N 50039669 1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10-yl]-4-methyl-piperazine::CHEMBL90977 D(2) dopamine receptor Homo sapiens 730 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323890 103946864 CHEMBL90977 ZINC13738220 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062265 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 220 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062266 CN1CCN(CC1)C1=Cc2cc(Cl)ccc2C(=C(C)C)c2ccccc12 InChI=1S/C23H25ClN2/c1-16(2)23-19-9-8-18(24)14-17(19)15-22(20-6-4-5-7-21(20)23)26-12-10-25(3)11-13-26/h4-9,14-15H,10-13H2,1-3H3 QCJIDMPIJUWNKR-UHFFFAOYSA-N 50010593 1-(2-Chloro-5-isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL328246 D(2) dopamine receptor Homo sapiens 690 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323870 103923368 CHEMBL328246 ZINC13738221 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062267 CN1CCC(=CC1)C1=Cc2ccccc2C(=C)c2ccccc12 InChI=1S/C22H21N/c1-16-19-8-4-3-7-18(19)15-22(17-11-13-23(2)14-12-17)21-10-6-5-9-20(16)21/h3-11,15H,1,12-14H2,2H3 KSKCVJKDKBWMJB-UHFFFAOYSA-N 50039671 1-Methyl-4-(5-methylene-5H-dibenzo[a,d]cyclohepten-10-yl)-1,2,3,6-tetrahydro-pyridine::CHEMBL327713 D(2) dopamine receptor Homo sapiens 250 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039671&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086123 103946866 CHEMBL327713 ZINC13738224 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062269 CN1CCC(=CC1)C1=Cc2ccccc2C(=C(C)C)c2ccccc12 InChI=1S/C24H25N/c1-17(2)24-20-9-5-4-8-19(20)16-23(18-12-14-25(3)15-13-18)21-10-6-7-11-22(21)24/h4-12,16H,13-15H2,1-3H3 BFTXVLUTUUBYLQ-UHFFFAOYSA-N 50036443 4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine::CHEMBL94067 D(2) dopamine receptor Homo sapiens 570 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10449136 103944208 CHEMBL94067 ZINC13738227 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062270 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Homo sapiens 47 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062272 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(C)c2ccccc12 InChI=1S/C19H21ClN4/c1-22-9-11-24(12-10-22)19-15-5-3-4-6-17(15)23(2)18-8-7-14(20)13-16(18)21-19/h3-8,13H,9-12H2,1-2H3 XQIPQCHREHNRDI-UHFFFAOYSA-N 50028979 8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL266723 D(2) dopamine receptor Homo sapiens 1100 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028979&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11724853 103938109 CHEMBL266723 ZINC13738214 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062274 CC1c2ccccc2C=C(C2=CCN(C)CC2)c2ccccc12 InChI=1S/C22H23N/c1-16-19-8-4-3-7-18(19)15-22(17-11-13-23(2)14-12-17)21-10-6-5-9-20(16)21/h3-11,15-16H,12-14H2,1-2H3 ICCKEQYPLWYEKK-UHFFFAOYSA-N 50036444 1-Methyl-4-(5-methyl-5H-dibenzo[a,d]cyclohepten-10-yl)-1,2,3,6-tetrahydro-pyridine; hydrochloride::CHEMBL544184::CHEMBL91350 D(2) dopamine receptor Homo sapiens 680 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10424961 103944209 CHEMBL544184CHEMBL91350 ZINC13738226 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062301 CN1CCC(CC1)C1=Cc2cc(Cl)ccc2Cc2ccccc12 InChI=1S/C21H22ClN/c1-23-10-8-15(9-11-23)21-14-18-13-19(22)7-6-16(18)12-17-4-2-3-5-20(17)21/h2-7,13-15H,8-12H2,1H3 ZABVPBHKTKEJLW-UHFFFAOYSA-N 50028976 4-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-methyl-piperidine::CHEMBL7430 D(2) dopamine receptor Homo sapiens 560 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028976&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13014681 103938106 CHEMBL7430 ZINC13738215 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062307 CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Oc2ccccc12 InChI=1S/C19H19ClN2O/c1-21-8-10-22(11-9-21)17-13-14-12-15(20)6-7-18(14)23-19-5-3-2-4-16(17)19/h2-7,12-13H,8-11H2,1H3 QXTCIQSORSSPSR-UHFFFAOYSA-N 50028602 1-(2-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-piperazine::CHEMBL88464 D(2) dopamine receptor Homo sapiens 8.7 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12765116 103937814 CHEMBL88464 ZINC13738223 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062308 CN1CCN(CC1)C1=Cc2ccccc2C(=C(C)C)c2ccccc12 InChI=1S/C23H26N2/c1-17(2)23-19-9-5-4-8-18(19)16-22(20-10-6-7-11-21(20)23)25-14-12-24(3)13-15-25/h4-11,16H,12-15H2,1-3H3 NJUSHLPQKJYNMD-UHFFFAOYSA-N 50010597 1-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL88870 D(2) dopamine receptor Homo sapiens 290 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010597&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323876 103923372 CHEMBL88870 ZINC13738222 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062309 CN1CCN(CC1)C1=Cc2ccccc2C(=C)c2ccccc12 InChI=1S/C21H22N2/c1-16-18-8-4-3-7-17(18)15-21(20-10-6-5-9-19(16)20)23-13-11-22(2)12-14-23/h3-10,15H,1,11-14H2,2H3 NBFZVLQBKCNVGZ-UHFFFAOYSA-N 50010598 1-Methyl-4-(5-methylene-5H-dibenzo[a,d]cyclohepten-10-yl)-piperazine::CHEMBL91310 D(2) dopamine receptor Homo sapiens 57 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323851 103923373 CHEMBL91310 ZINC13738219 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062323 C[C@H]1c2ccccc2C=C(C2=CCN(C)CC2)c2ccccc12 InChI=1S/C22H23N/c1-16-19-8-4-3-7-18(19)15-22(17-11-13-23(2)14-12-17)21-10-6-5-9-20(16)21/h3-11,15-16H,12-14H2,1-2H3/t16-/m0/s1 ICCKEQYPLWYEKK-INIZCTEOSA-N 50039673 1-Methyl-4-((S)-5-methyl-5H-dibenzo[a,d]cyclohepten-10-yl)-1,2,3,6-tetrahydro-pyridine::CHEMBL89719 D(2) dopamine receptor Homo sapiens 730 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039673&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10040546 103946868 CHEMBL89719 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062325 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Oc2ccccc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-7-6-13(19)12-15(17)20-18/h2-7,12H,8-11H2,1H3 AWHNHDGHHNGACT-UHFFFAOYSA-N 50028980 8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine::8-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::CHEMBL7828::Isoloxapine D(2) dopamine receptor Homo sapiens 150 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028980&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381810 103938110 CHEMBL7828 ZINC13532241 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062326 CN1CCN(CC1)C1=Cc2ccccc2Oc2ccccc12 InChI=1S/C19H20N2O/c1-20-10-12-21(13-11-20)17-14-15-6-2-4-8-18(15)22-19-9-5-3-7-16(17)19/h2-9,14H,10-13H2,1H3 ZCCUIFWJESTQQQ-UHFFFAOYSA-N 50028598 1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine::CHEMBL89970 D(2) dopamine receptor Homo sapiens 21 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 210956 103937810 CHEMBL89970 ZINC26648468 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062327 CN1CCN(CC1)C1=Cc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C19H19ClN2O/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,12-13H,8-11H2,1H3 OTKUTGIVEREJLL-UHFFFAOYSA-N 50028600 1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-piperazine::CHEMBL90882 D(2) dopamine receptor Homo sapiens 2.5 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028600&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 32224 103937812 CHEMBL90882 ZINC22309494 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062331 CN1CCN(CC1)C1=Cc2ccccc2Cc2ccc(Cl)cc12 InChI=1S/C20H21ClN2/c1-22-8-10-23(11-9-22)20-13-16-5-3-2-4-15(16)12-17-6-7-18(21)14-19(17)20/h2-7,13-14H,8-12H2,1H3 SFRWZRKAHVGRFO-UHFFFAOYSA-N 50028601 1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL7617 D(2) dopamine receptor Homo sapiens 1 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13014692 103937813 CHEMBL7617 ZINC13532247 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062339 CC1CCN(CC1)C1=Cc2cc(Cl)ccc2Cc2ccccc12 InChI=1S/C21H22ClN/c1-15-8-10-23(11-9-15)21-14-18-13-19(22)7-6-16(18)12-17-4-2-3-5-20(17)21/h2-7,13-15H,8-12H2,1H3 AENACYRRZFSOSG-UHFFFAOYSA-N 50028978 1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperidine::CHEMBL269396 D(2) dopamine receptor Homo sapiens 1400 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028978&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13014683 103938108 CHEMBL269396 ZINC13738216 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062343 C[C@@H]1c2ccccc2C=C(C2=CCN(C)CC2)c2ccccc12 InChI=1S/C22H23N/c1-16-19-8-4-3-7-18(19)15-22(17-11-13-23(2)14-12-17)21-10-6-5-9-20(16)21/h3-11,15-16H,12-14H2,1-2H3/t16-/m1/s1 ICCKEQYPLWYEKK-MRXNPFEDSA-N 50039672 1-Methyl-4-((R)-5-methyl-5H-dibenzo[a,d]cyclohepten-10-yl)-1,2,3,6-tetrahydro-pyridine::CHEMBL90654 D(2) dopamine receptor Homo sapiens 640 ChEMBL 10.1021/jm00043a008 10.7270/Q28051NX 8064797 Phillips, ST; de Paulis, T; Baron, BM; Siegel, BW; Seeman, P; Van Tol, HH; Guan, HC; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11779642 103946867 CHEMBL90654 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063637 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063640 COc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13?,15-/m0/s1 ZRAGXRIXRXDXCR-WUJWULDRSA-N 50040168 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL276825 D(2) dopamine receptor Homo sapiens >339 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266623 103972228 CHEMBL276825 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063646 COc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13?,15-/m1/s1 ZRAGXRIXRXDXCR-AWKYBWMHSA-N 50040170 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10570 D(2) dopamine receptor Homo sapiens 78.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266689 103972230 CHEMBL10570 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063654 COc1cccc2CC[C@@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13?,14-/m1/s1 VRRJFCMGNMFNOE-ARLHGKGLSA-N 50040177 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10270 D(2) dopamine receptor Homo sapiens 6.7 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266664 103972237 CHEMBL10270 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063658 COc1cccc2CC[C@@H]3C(CCN3CCc3ccccc3)c12 InChI=1S/C21H25NO/c1-23-20-9-5-8-17-10-11-19-18(21(17)20)13-15-22(19)14-12-16-6-3-2-4-7-16/h2-9,18-19H,10-15H2,1H3/t18?,19-/m1/s1 PPFLJANGUQOHFJ-MUMRKEEXSA-N 50040169 9-Methoxy-3-phenethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL267086 D(2) dopamine receptor Homo sapiens >339 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266678 103972229 CHEMBL267086 ZINC26008190 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063659 COc1cccc2CC[C@H]3C(CCN3CCc3ccccc3)c12 InChI=1S/C21H25NO/c1-23-20-9-5-8-17-10-11-19-18(21(17)20)13-15-22(19)14-12-16-6-3-2-4-7-16/h2-9,18-19H,10-15H2,1H3/t18?,19-/m0/s1 PPFLJANGUQOHFJ-GGYWPGCISA-N 50040178 9-Methoxy-3-phenethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL416519 D(2) dopamine receptor Homo sapiens 392 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266611 103972238 CHEMBL416519 ZINC26007035 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063663 Oc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12?,14-/m0/s1 MHHLELSXRBTNRD-PYMCNQPYSA-N 50040179 (Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL275543 D(2) dopamine receptor Homo sapiens 59 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266663 103972239 CHEMBL275543 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063673 Oc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12?,14-/m1/s1 MHHLELSXRBTNRD-TYZXPVIJSA-N 50040165 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10408 D(2) dopamine receptor Homo sapiens 108 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266677 103972225 CHEMBL10408 ZINC13826519 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063698 COc1cccc2CC[C@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13?,14-/m0/s1 VRRJFCMGNMFNOE-KZUDCZAMSA-N 50040166 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL418705 D(2) dopamine receptor Homo sapiens 77 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266613 103972226 CHEMBL418705 ZINC13826496 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50063699 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Homo sapiens 86 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062738 COc1cccc2CC[C@@H]3[C@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13-,14+/m0/s1 VRRJFCMGNMFNOE-UONOGXRCSA-N 50034339 (3aR,9bR)-3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic)3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL286205 D(2) dopamine receptor Homo sapiens 8.5 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10354437 103942540 CHEMBL286205 ZINC13826494 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062746 Oc1cccc2CC[C@@H]3[C@H](CCN3CC=C)c12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2/t12-,13+/m0/s1 NLAWPJROLJRPAW-QWHCGFSZSA-N 50034321 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL283738 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353777 103942522 CHEMBL283738 ZINC13826915 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062739 CCCN1CC[C@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1 SHOJVFLWKSRVPH-TZMCWYRMSA-N 50034349 (3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL24588 D(2) dopamine receptor Homo sapiens 93 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353846 103942550 CHEMBL24588 ZINC28756688 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062750 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m0/s1 ZRAGXRIXRXDXCR-DZGCQCFKSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 D(2) dopamine receptor Homo sapiens 18.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 ZINC00004906 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062755 CCCN1CC[C@@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14+/m0/s1 SHOJVFLWKSRVPH-GXTWGEPZSA-N 50034363 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL26560 D(2) dopamine receptor Homo sapiens 218 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034363&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466454 103942564 CHEMBL26560 ZINC13826523 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062764 COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1 ZRAGXRIXRXDXCR-UKRRQHHQSA-N 50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222 D(2) dopamine receptor Homo sapiens 50 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037436 103942565 CHEMBL24222 ZINC13826504 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062766 Oc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1 MHHLELSXRBTNRD-TZMCWYRMSA-N 50034356 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL25483 D(2) dopamine receptor Homo sapiens 4.1 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466368 103942557 CHEMBL25483 ZINC13826519 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062776 Oc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14+/m0/s1 MHHLELSXRBTNRD-GXTWGEPZSA-N 50034355 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::(3aR,9bS)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL285873 D(2) dopamine receptor Homo sapiens 75 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014056 103942556 CHEMBL285873 ZINC13826517 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062779 Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12 InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1 GNOHLPXINNYCLR-TZMCWYRMSA-N 50034346 (3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aS,9aR)-1-allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11363 D(2) dopamine receptor Homo sapiens 235 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014057 103942547 CHEMBL11363 ZINC13826580 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062782 CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1 DYVLYWKEJHHXOH-TZMCWYRMSA-N 50034352 (3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aS,9aR)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11066 D(2) dopamine receptor Homo sapiens 2.40 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105311 103942553 CHEMBL11066 ZINC13826575 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50062783 CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1 HDCVYYTWHHFQGS-UKRRQHHQSA-N 50034324 (3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::(3aS,9aR)-5-methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11388 D(2) dopamine receptor Homo sapiens 75.0 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377224 103942525 CHEMBL11388 ZINC13826563 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068917 Cc1cc(F)ccc1NC(=O)CN1CCC(CC1)c1cccc[n+]1[O-] InChI=1S/C19H22FN3O2/c1-14-12-16(20)5-6-17(14)21-19(24)13-22-10-7-15(8-11-22)18-4-2-3-9-23(18)25/h2-6,9,12,15H,7-8,10-11,13H2,1H3,(H,21,24) MYDLUAXWIJFAIL-UHFFFAOYSA-N 50200041 CHEMBL219261::N-(2-methyl-4-fluorophenyl)-2-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-yl)acetamide D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16094681 104080480 CHEMBL219261 ZINC35075422 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068932 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068941 Cc1cccc(c1)C(=O)NCN1CCC(CC1)c1cccc[n+]1[O-] InChI=1S/C19H23N3O2/c1-15-5-4-6-17(13-15)19(23)20-14-21-11-8-16(9-12-21)18-7-2-3-10-22(18)24/h2-7,10,13,16H,8-9,11-12,14H2,1H3,(H,20,23) PUMMPCXNEPHBNN-UHFFFAOYSA-N 50200050 ABT-670::CHEMBL219182::methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'ylmethyl)benzamide D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16094676 104080489 CHEMBL219182 ZINC35075418 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068943 Cc1cccc(NC(=O)CN2CCC(CC2)c2cccc[n+]2[O-])c1 InChI=1S/C19H23N3O2/c1-15-5-4-6-17(13-15)20-19(23)14-21-11-8-16(9-12-21)18-7-2-3-10-22(18)24/h2-7,10,13,16H,8-9,11-12,14H2,1H3,(H,20,23) NJHQEWHCSIFEMP-UHFFFAOYSA-N 50200030 2-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'bipyridine]-1'-yl)-N-(m-tolyl)acetamide::CHEMBL219185 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16094677 104080469 CHEMBL219185 ZINC35075419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068949 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 5.8 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068957 Cc1cccc(c1)C(=O)NCN1CCC(CC1)c1ccccn1 InChI=1S/C19H23N3O/c1-15-5-4-6-17(13-15)19(23)21-14-22-11-8-16(9-12-22)18-7-2-3-10-20-18/h2-7,10,13,16H,8-9,11-12,14H2,1H3,(H,21,23) MJWBNONYVUDZCQ-UHFFFAOYSA-N 50200043 3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide::CHEMBL216794 D(2) dopamine receptor Homo sapiens 3500 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16094699 104080482 CHEMBL216794 ZINC35075439 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068964 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 1.8 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068977 Oc1ccc(nc1)N1CCN(Cc2nc3ccccc3[nH]2)CC1 InChI=1S/C17H19N5O/c23-13-5-6-17(18-11-13)22-9-7-21(8-10-22)12-16-19-14-3-1-2-4-15(14)20-16/h1-6,11,23H,7-10,12H2,(H,19,20) CBDXXUZXRDBOGH-UHFFFAOYSA-N 50200029 6-(4-((1H-benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)pyridin-3-ol::A-425444::CHEMBL219179 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200029&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861462 104080468 CHEMBL219179 ZINC33996286 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068980 COc1ccccc1C1CCN(CNC(=O)c2cccc(C)c2)CC1 InChI=1S/C21H26N2O2/c1-16-6-5-7-18(14-16)21(24)22-15-23-12-10-17(11-13-23)19-8-3-4-9-20(19)25-2/h3-9,14,17H,10-13,15H2,1-2H3,(H,22,24) LAFUMJMKVVCEGP-UHFFFAOYSA-N 50200028 2-methoxy-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)-benzamide::CHEMBL376092 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16094698 104080467 CHEMBL376092 ZINC35075438 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50068982 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1021/jm049484q 10.7270/Q2639R8M 15588094 Saitton, S; Del Tredici, AL; Mohell, N; Vollinga, RC; Boström, D; Kihlberg, J; Luthman, K G£teborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50071105 CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C(C)=O)c3c2C1 InChI=1S/C20H28N2O/c1-4-10-22(11-5-2)16-8-6-15-7-9-19-20(17(15)12-16)18(13-21-19)14(3)23/h7,9,13,16,21H,4-6,8,10-12H2,1-3H3/t16-/m0/s1 VMXHWDJFMZJHSQ-INIZCTEOSA-N 50044238 CHEMBL63449::S-(-)-1-(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-ethanone D(2) dopamine receptor Homo sapiens 423.0 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44305180 103975561 CHEMBL63449 ZINC13741709 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50071106 CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C(C)=O)c3c2C1 InChI=1S/C20H28N2O/c1-4-10-22(11-5-2)16-8-6-15-7-9-19-20(17(15)12-16)18(13-21-19)14(3)23/h7,9,13,16,21H,4-6,8,10-12H2,1-3H3/t16-/m1/s1 VMXHWDJFMZJHSQ-MRXNPFEDSA-N 50044237 CHEMBL65274::R-(+)-1-(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-ethanone D(2) dopamine receptor Homo sapiens 17 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44305165 103975560 CHEMBL65274 ZINC13741708 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50072260 C[C@@H]1Cc2ccc3C[C@H]4N(C)CCc5cccc(c45)-c3c2O1 InChI=1S/C20H21NO/c1-12-10-15-7-6-14-11-17-18-13(8-9-21(17)2)4-3-5-16(18)19(14)20(15)22-12/h3-7,12,17H,8-11H2,1-2H3/t12-,17-/m1/s1 MSFBLSXHRFJARJ-SJKOYZFVSA-N 50309808 CHEMBL597094::Cis-N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporphine D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm9015763 10.7270/Q2T154KK 20041669 Liu, Z; Zhang, H; Ye, N; Zhang, J; Wu, Q; Sun, P; Li, L; Zhen, X; Zhang, A Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46180398 104164169 CHEMBL597094 ZINC45367060 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50071364 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Homo sapiens 0.200000 ChEMBL 10.1021/jm00069a010 10.7270/Q2QF8RZ9 8355253 Ismaiel, AM; De Los Angeles, J; Teitler, M; Ingher, S; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50071382 Fc1ccc(OCCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)cc1 InChI=1S/C22H26FN3O2/c23-18-7-9-20(10-8-18)28-16-4-13-25-14-11-22(12-15-25)21(27)24-17-26(22)19-5-2-1-3-6-19/h1-3,5-10H,4,11-17H2,(H,24,27) FJUKDAZEABGEIH-UHFFFAOYSA-N 86525 AMI-193::CAS_77445::CHEMBL79834::NSC_77445 D(2) dopamine receptor Homo sapiens 3 ChEMBL 10.1021/jm00069a010 10.7270/Q2QF8RZ9 8355253 Ismaiel, AM; De Los Angeles, J; Teitler, M; Ingher, S; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68186 136352574 CHEMBL79834 ZINC01846593 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50079160 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 89 ChEMBL 10.1016/j.ejmech.2014.02.058 10.7270/Q2QV3P1M 24631727 Selent, J; Marti-Solano, M; Rodríguez, J; Atanes, P; Brea, J; Castro, M; Sanz, F; Loza, MI; Pastor, M Universitat Pompeu Fabra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50079161 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 89.1 ChEMBL 10.1016/j.ejmech.2014.02.058 10.7270/Q2QV3P1M 24631727 Selent, J; Marti-Solano, M; Rodríguez, J; Atanes, P; Brea, J; Castro, M; Sanz, F; Loza, MI; Pastor, M Universitat Pompeu Fabra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50079162 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Homo sapiens 23 ChEMBL 10.1016/j.ejmech.2014.02.058 10.7270/Q2QV3P1M 24631727 Selent, J; Marti-Solano, M; Rodríguez, J; Atanes, P; Brea, J; Castro, M; Sanz, F; Loza, MI; Pastor, M Universitat Pompeu Fabra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50079163 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Homo sapiens 23.4 ChEMBL 10.1016/j.ejmech.2014.02.058 10.7270/Q2QV3P1M 24631727 Selent, J; Marti-Solano, M; Rodríguez, J; Atanes, P; Brea, J; Castro, M; Sanz, F; Loza, MI; Pastor, M Universitat Pompeu Fabra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50078127 C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1 XBGWTWPYCTZIIE-HXUWFJFHSA-N 50048299 4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL335545::CI-1007 D(2) dopamine receptor Homo sapiens 25.5 ChEMBL 10.1021/jm00026a007 10.7270/Q2VQ31SG 8544176 Wright, JL; Downing, DM; Feng, MR; Hayes, RN; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127698 103978825 CHEMBL335545 ZINC03792322 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50078128 Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccc(O)cc2)CC1 InChI=1S/C24H27NO2/c26-23-8-4-19(5-9-23)21-12-14-25(15-13-21)17-18-2-1-3-22(16-18)20-6-10-24(27)11-7-20/h3-12,18,26-27H,1-2,13-17H2/t18-/m1/s1 VMTIAIJOJOQAEM-GOSISDBHSA-N 50048300 4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-tetrahydro pyridin-4-yl)phenol::CHEMBL147159 D(2) dopamine receptor Homo sapiens 10.3 ChEMBL 10.1021/jm00026a007 10.7270/Q2VQ31SG 8544176 Wright, JL; Downing, DM; Feng, MR; Hayes, RN; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10713620 103978826 CHEMBL147159 ZINC13603955 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50078135 Oc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 InChI=1S/C24H27NO/c26-24-11-9-21(10-12-24)23-8-4-5-19(17-23)18-25-15-13-22(14-16-25)20-6-2-1-3-7-20/h1-3,6-13,19,26H,4-5,14-18H2/t19-/m1/s1 GHLIXCKZQCRDAX-LJQANCHMSA-N 50048302 4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-cyclohex-1-enyl]-phenol::CHEMBL357416 D(2) dopamine receptor Homo sapiens 0.2 ChEMBL 10.1021/jm00026a007 10.7270/Q2VQ31SG 8544176 Wright, JL; Downing, DM; Feng, MR; Hayes, RN; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 178078 103978828 CHEMBL357416 ZINC06096034 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50078137 Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccccc2)CC1 InChI=1S/C24H27NO/c26-24-11-9-21(10-12-24)22-13-15-25(16-14-22)18-19-5-4-8-23(17-19)20-6-2-1-3-7-20/h1-3,6-13,19,26H,4-5,14-18H2/t19-/m1/s1 RIRRORJZVJGNAL-LJQANCHMSA-N 50048301 4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-phenol::CHEMBL356269 D(2) dopamine receptor Homo sapiens 94 ChEMBL 10.1021/jm00026a007 10.7270/Q2VQ31SG 8544176 Wright, JL; Downing, DM; Feng, MR; Hayes, RN; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10759963 103978827 CHEMBL356269 ZINC13603953 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50078361 CC(C)(C)[C@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25+/m1/s1 ZZJYIKPMDIWRSN-RQTOMXEWSA-N 50292410 (-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(butaclamol)::(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((-)-butaclamol)::Butaclamol::CHEMBL479587::l-Butaclamol D(2) dopamine receptor Homo sapiens >0.000 ChEMBL 10.1021/jm00382a002 10.7270/Q2542P5T 3156993 Neumeyer, JL; Guan, JH; Niznik, HB; Dumbrille-Ross, A; Seeman, P; Padmanabhan, S; Elmaleh, DR TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292410&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24847750 104133961 CHEMBL479587 ZINC40933021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080707 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.4 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080709 OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 InChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 LLBLNMUONVVVPG-UHFFFAOYSA-N 50050467 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol::3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole::4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol::CHEMBL445102::L-741626::L741,626 D(2) dopamine receptor Homo sapiens 7.5 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133633 103947637 CHEMBL445102 177 ZINC00006788 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080712 COc1cccc2[nH]cc(CN3CCC(O)(CC3)c3ccc(I)cc3)c12 InChI=1S/C21H23IN2O2/c1-26-19-4-2-3-18-20(19)15(13-23-18)14-24-11-9-21(25,10-12-24)16-5-7-17(22)8-6-16/h2-8,13,23,25H,9-12,14H2,1H3 LMUWKYOZOCNQDQ-UHFFFAOYSA-N 50322229 4-(4-Iodophenyl)-1-((4-methoxy-1H-indol-3-yl)methyl)-piperidin-4-ol oxalate::CHEMBL1173287 D(2) dopamine receptor Homo sapiens 0.900000 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322229&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46912547 104143758 CHEMBL1173287 ZINC53244094 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080715 Fc1ccc(CN2CCC(CC2)Nc2ccc(nn2)C(F)(F)F)cc1F InChI=1S/C17H17F5N4/c18-13-2-1-11(9-14(13)19)10-26-7-5-12(6-8-26)23-16-4-3-15(24-25-16)17(20,21)22/h1-4,9,12H,5-8,10H2,(H,23,25) UVUYWJWYRLJHEN-UHFFFAOYSA-N 50003063 CHEMBL3234237 D(2) dopamine receptor Homo sapiens 158 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003063&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16058752 242056376 CHEMBL3234237 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080716 CCN1c2cc(ccc2[S+]([O-])c2ccccc2C1=O)C(=O)NCc1ccc(OC)cc1 InChI=1S/C24H22N2O4S/c1-3-26-20-14-17(23(27)25-15-16-8-11-18(30-2)12-9-16)10-13-22(20)31(29)21-7-5-4-6-19(21)24(26)28/h4-14H,3,15H2,1-2H3,(H,25,27) UFOYCFLCNQFALX-UHFFFAOYSA-N 50003064 CHEMBL1503220 D(2) dopamine receptor Homo sapiens 300 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003064&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16007814 242056377 CHEMBL1503220 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080717 CN1c2cc(ccc2[S+]([O-])c2ccccc2C1=O)C(=O)NCCc1cccs1 InChI=1S/C21H18N2O3S2/c1-23-17-13-14(20(24)22-11-10-15-5-4-12-27-15)8-9-19(17)28(26)18-7-3-2-6-16(18)21(23)25/h2-9,12-13H,10-11H2,1H3,(H,22,24) YXLLQNMKIDBOGH-UHFFFAOYSA-N 50003065 CHEMBL3234522 D(2) dopamine receptor Homo sapiens 190 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383431 242056378 CHEMBL3234522 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080724 CCN1c2cc(ccc2[S@@+]([O-])c2ccccc2C1=O)C(=O)NCc1ccc(F)cc1 InChI=1S/C23H19FN2O3S/c1-2-26-19-13-16(22(27)25-14-15-7-10-17(24)11-8-15)9-12-21(19)30(29)20-6-4-3-5-18(20)23(26)28/h3-13H,2,14H2,1H3,(H,25,27)/t30-/m0/s1 VPRRPJPYZLZPNF-PMERELPUSA-N 50003066 CHEMBL3234536 D(2) dopamine receptor Homo sapiens 90 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003066&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383430 242056379 CHEMBL3234536 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080726 CCN1c2cc(ccc2[S@@+]([O-])c2ccccc2C1=O)C(=O)NCc1ccc(cc1)C#N InChI=1S/C24H19N3O3S/c1-2-27-20-13-18(23(28)26-15-17-9-7-16(14-25)8-10-17)11-12-22(20)31(30)21-6-4-3-5-19(21)24(27)29/h3-13H,2,15H2,1H3,(H,26,28)/t31-/m0/s1 VUTNNUCTOQWFCV-HKBQPEDESA-N 50003068 CHEMBL3234537 D(2) dopamine receptor Homo sapiens 23 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003068&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383414 242056381 CHEMBL3234537 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080731 CCN1c2cc(ccc2[S@@+]([O-])c2ccccc2C1=O)C(=O)N[C@H](C)c1ccc(Br)cc1 InChI=1S/C24H21BrN2O3S/c1-3-27-20-14-17(23(28)26-15(2)16-8-11-18(25)12-9-16)10-13-22(20)31(30)21-7-5-4-6-19(21)24(27)29/h4-15H,3H2,1-2H3,(H,26,28)/t15-,31+/m1/s1 PGBIKSUFINVTHD-QLCIJSRNSA-N 50003069 CHEMBL3234538 D(2) dopamine receptor Homo sapiens 530 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003069&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383397 242056382 CHEMBL3234538 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080732 CCN1c2cc(ccc2[S@@+]([O-])c2ccccc2C1=O)C(=O)N[C@H](C)c1ccc2ccccc2c1 InChI=1S/C28H24N2O3S/c1-3-30-24-17-22(14-15-26(24)34(33)25-11-7-6-10-23(25)28(30)32)27(31)29-18(2)20-13-12-19-8-4-5-9-21(19)16-20/h4-18H,3H2,1-2H3,(H,29,31)/t18-,34+/m1/s1 IGIPSUCYDDNAQY-JTYJAPAGSA-N 50003070 CHEMBL3234539 D(2) dopamine receptor Homo sapiens 290 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003070&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383434 242056383 CHEMBL3234539 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080733 CN1c2cc(ccc2[S@@+]([O-])c2ccccc2C1=O)C(=O)NCc1ccc(Br)cc1 InChI=1S/C22H17BrN2O3S/c1-25-18-12-15(21(26)24-13-14-6-9-16(23)10-7-14)8-11-20(18)29(28)19-5-3-2-4-17(19)22(25)27/h2-12H,13H2,1H3,(H,24,26)/t29-/m0/s1 NXRNOJKUXYWBIA-LJAQVGFWSA-N 50003071 CHEMBL3234541 D(2) dopamine receptor Homo sapiens 240 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383405 242056384 CHEMBL3234541 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080737 CN1c2cc(ccc2[S@@+]([O-])c2ccccc2C1=O)C(=O)NCc1cccnc1 InChI=1S/C21H17N3O3S/c1-24-17-11-15(20(25)23-13-14-5-4-10-22-12-14)8-9-19(17)28(27)18-7-3-2-6-16(18)21(24)26/h2-12H,13H2,1H3,(H,23,25)/t28-/m0/s1 RANRSXNHVJZBGA-NDEPHWFRSA-N 50003072 CHEMBL3234542 D(2) dopamine receptor Homo sapiens 310 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003072&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383436 103917088 CHEMBL3234542 ZINC95540410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080739 CN1c2cc(ccc2[S@@+]([O-])c2ccccc2C1=O)C(=O)NCCN1CCCC1 InChI=1S/C21H23N3O3S/c1-23-17-14-15(20(25)22-10-13-24-11-4-5-12-24)8-9-19(17)28(27)18-7-3-2-6-16(18)21(23)26/h2-3,6-9,14H,4-5,10-13H2,1H3,(H,22,25)/t28-/m0/s1 PYVFEIJTIUOBFF-NDEPHWFRSA-N 50003073 CHEMBL3234543 D(2) dopamine receptor Homo sapiens 210 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383401 242056385 CHEMBL3234543 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080741 CN1c2cc(ccc2[S@@+]([O-])c2ccccc2C1=O)C(=O)NCCc1cccs1 InChI=1S/C21H18N2O3S2/c1-23-17-13-14(20(24)22-11-10-15-5-4-12-27-15)8-9-19(17)28(26)18-7-3-2-6-16(18)21(23)25/h2-9,12-13H,10-11H2,1H3,(H,22,24)/t28-/m0/s1 YXLLQNMKIDBOGH-NDEPHWFRSA-N 50003074 CHEMBL3234544 D(2) dopamine receptor Homo sapiens 100 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003074&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57377246 242056386 CHEMBL3234544 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50080770 CN1c2cc(ccc2[S@+]([O-])c2ccccc2C1=O)C(=O)NCCc1cccs1 InChI=1S/C21H18N2O3S2/c1-23-17-13-14(20(24)22-11-10-15-5-4-12-27-15)8-9-19(17)28(26)18-7-3-2-6-16(18)21(23)25/h2-9,12-13H,10-11H2,1H3,(H,22,24)/t28-/m1/s1 YXLLQNMKIDBOGH-MUUNZHRXSA-N 50003075 CHEMBL3234545 D(2) dopamine receptor Homo sapiens >50000 ChEMBL 10.1021/jm500126s 10.7270/Q2MW2JN2 24666157 Xiao, J; Free, RB; Barnaeva, E; Conroy, JL; Doyle, T; Miller, B; Bryant-Genevier, M; Taylor, MK; Hu, X; Dulcey, AE; Southall, N; Ferrer, M; Titus, S; Zheng, W; Sibley, DR; Marugan, JJ National Center for Advancing Translational Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003075&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57383408 242056387 CHEMBL3234545 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082030 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.4 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082031 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ccccc23)CC1 InChI=1S/C19H20ClN3/c20-16-5-7-17(8-6-16)23-11-9-22(10-12-23)14-15-13-21-19-4-2-1-3-18(15)19/h1-8,13,21H,9-12,14H2 NRWWWLAGZMNIDV-UHFFFAOYSA-N 50050462 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole::CHEMBL268799 D(2) dopamine receptor Homo sapiens 71 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 511482 103947632 CHEMBL268799 ZINC53050360 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082033 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OGJGQVFWEPNYSB-UHFFFAOYSA-N 85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853 D(2) dopamine receptor Homo sapiens 960 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L74 6IQL 5311200 136351193 CHEMBL555670CHEMBL267014 3303 ZINC25760037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082041 C(N1CCC(CC1)c1ccccc1)c1c[nH]c2ccccc12 InChI=1S/C20H22N2/c1-2-6-16(7-3-1)17-10-12-22(13-11-17)15-18-14-21-20-9-5-4-8-19(18)20/h1-9,14,17,21H,10-13,15H2 XNXQFTTXHFQTRX-UHFFFAOYSA-N 50050468 3-(4-Phenyl-piperidin-1-ylmethyl)-1H-indole::CHEMBL59103 D(2) dopamine receptor Homo sapiens 110 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10851078 103947638 CHEMBL59103 ZINC13755886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082042 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 74 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082046 CC1CCN(Cc2c[nH]c3ccccc23)CC1 InChI=1S/C15H20N2/c1-12-6-8-17(9-7-12)11-13-10-16-15-5-3-2-4-14(13)15/h2-5,10,12,16H,6-9,11H2,1H3 DGCGMYNLCDVYMB-UHFFFAOYSA-N 50050469 3-(4-Methyl-piperidin-1-ylmethyl)-1H-indole::CHEMBL57478 D(2) dopamine receptor Homo sapiens 5500 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDV 5QOM,5QPN,5SDC 30438 103947639 CHEMBL57478 ZINC00142608 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082047 Ic1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19IN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OOEUHRGMLFVKQO-UHFFFAOYSA-N 50050465 3-[4-(4-Iodo-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL60518 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603897 103947635 CHEMBL60518 978 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082052 OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 InChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 LLBLNMUONVVVPG-UHFFFAOYSA-N 50050467 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol::3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole::4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol::CHEMBL445102::L-741626::L741,626 D(2) dopamine receptor Homo sapiens 2.4 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133633 103947637 CHEMBL445102 177 ZINC00006788 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082058 C(N1CCCCC1)c1c[nH]c2ccccc12 InChI=1S/C14H18N2/c1-4-8-16(9-5-1)11-12-10-15-14-7-3-2-6-13(12)14/h2-3,6-7,10,15H,1,4-5,8-9,11H2 HPKXPFRRVVWAPD-UHFFFAOYSA-N 50050466 3-Piperidin-1-ylmethyl-1H-indole::CHEMBL57535 D(2) dopamine receptor Homo sapiens >1300 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21454 103947636 CHEMBL57535 ZINC00050819 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082059 C(N1CCN(CC1)c1ccccc1)c1c[nH]c2ccccc12 InChI=1S/C19H21N3/c1-2-6-17(7-3-1)22-12-10-21(11-13-22)15-16-14-20-19-9-5-4-8-18(16)19/h1-9,14,20H,10-13,15H2 FDOZNCJWYJMHAG-UHFFFAOYSA-N 50050464 3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole::CHEMBL59324 D(2) dopamine receptor Homo sapiens 120 ChEMBL 10.1021/jm9600712 10.7270/Q2MW2G6D 8642550 Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 233952 103947634 CHEMBL59324 ZINC53151307 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082077 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.4 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082078 Cc1c(noc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C23H25ClN2O/c1-17-22(25-27-23(17)20-7-9-21(24)10-8-20)19-12-15-26(16-13-19)14-11-18-5-3-2-4-6-18/h2-10,19H,11-16H2,1H3 QDMAKDIDFJTXEL-UHFFFAOYSA-N 50050476 4-[5-(4-Chloro-phenyl)-4-methyl-isoxazol-3-yl]-1-phenethyl-piperidine::4-[5-(4-Chloro-phenyl)-4-methyl-isoxazol-3-yl]-1-phenethyl-piperidine (L-741742)::CHEMBL444309::L-741742 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133008 103947646 CHEMBL444309 3302 ZINC00602172 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082080 Cc1c([nH]nc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C23H26ClN3/c1-17-22(19-7-9-21(24)10-8-19)25-26-23(17)20-12-15-27(16-13-20)14-11-18-5-3-2-4-6-18/h2-10,20H,11-16H2,1H3,(H,25,26) GNGQVEIKYIVCPC-UHFFFAOYSA-N 50050474 4-[5-(4-Chloro-phenyl)-4-methyl-1H-pyrazol-3-yl]-1-phenethyl-piperidine::CHEMBL61079 D(2) dopamine receptor Homo sapiens 290 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10619737 103947644 CHEMBL61079 ZINC13755888 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082081 Cc1c(onc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C23H25ClN2O/c1-17-22(19-7-9-21(24)10-8-19)25-27-23(17)20-12-15-26(16-13-20)14-11-18-5-3-2-4-6-18/h2-10,20H,11-16H2,1H3 CCWCGSVNRVVPNM-UHFFFAOYSA-N 50050471 4-[3-(4-Chloro-phenyl)-4-methyl-isoxazol-5-yl]-1-phenethyl-piperidine::CHEMBL293341 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5029739 103947641 CHEMBL293341 ZINC02572468 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082083 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 74 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082086 Clc1ccc(CN2CCC(CC2)c2cc(no2)-c2ccc(Cl)cc2)cc1 InChI=1S/C21H20Cl2N2O/c22-18-5-1-15(2-6-18)14-25-11-9-17(10-12-25)21-13-20(24-26-21)16-3-7-19(23)8-4-16/h1-8,13,17H,9-12,14H2 BKCOTBJYDGSUFC-UHFFFAOYSA-N 50050475 1-(4-Chloro-benzyl)-4-[3-(4-chloro-phenyl)-isoxazol-5-yl]-piperidine::CHEMBL61195 D(2) dopamine receptor Homo sapiens 130 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691599 103947645 CHEMBL61195 ZINC13755890 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082069 Clc1ccc(CN2CCC(CC2)c2cc(on2)-c2ccc(Cl)cc2)cc1 InChI=1S/C21H20Cl2N2O/c22-18-5-1-15(2-6-18)14-25-11-9-16(10-12-25)20-13-21(26-24-20)17-3-7-19(23)8-4-17/h1-8,13,16H,9-12,14H2 IGAYGUGEWYBNRY-UHFFFAOYSA-N 50050470 1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazol-3-yl]-piperidine::CHEMBL58296 D(2) dopamine receptor Homo sapiens 160 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11794570 103947640 CHEMBL58296 ZINC13755889 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082070 Clc1ccc(CN2CCC(CC2)c2cc(n[nH]2)-c2ccc(Cl)cc2)cc1 InChI=1S/C21H21Cl2N3/c22-18-5-1-15(2-6-18)14-26-11-9-17(10-12-26)21-13-20(24-25-21)16-3-7-19(23)8-4-16/h1-8,13,17H,9-12,14H2,(H,24,25) YATPAHDOUJPRNV-UHFFFAOYSA-N 50050473 1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-2H-pyrazol-3-yl]-piperidine::CHEMBL61080 D(2) dopamine receptor Homo sapiens 240 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3746693 103947643 CHEMBL61080 ZINC00837039 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50082071 Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C22H24ClN3/c23-20-8-6-18(7-9-20)21-16-22(25-24-21)19-11-14-26(15-12-19)13-10-17-4-2-1-3-5-17/h1-9,16,19H,10-15H2,(H,24,25) YCDXELFFFUYKMO-UHFFFAOYSA-N 50050472 4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethyl-piperidine::4-[5-(4-Chloro-phenyl)-2H-pyrazol-3-yl]-1-phenethyl-piperidine::CHEMBL6416 D(2) dopamine receptor Homo sapiens 520 ChEMBL 10.1021/jm960072u 10.7270/Q2H41QG0 8642551 Rowley, M; Broughton, HB; Collins, I; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618874 103947642 CHEMBL6416 ZINC13755887 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50083285 COc1cc(Br)cc(C(=O)NCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)c1OC InChI=1S/C23H28BrCl2N3O3/c1-31-20-15-16(24)14-17(22(20)32-2)23(30)27-8-3-4-9-28-10-12-29(13-11-28)19-7-5-6-18(25)21(19)26/h5-7,14-15H,3-4,8-13H2,1-2H3,(H,27,30) RYXXRKZWJMNUEJ-UHFFFAOYSA-N 50137626 5-Bromo-N-{4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-2,3-dimethoxy-benzamide::CHEMBL59713 D(2) dopamine receptor Homo sapiens 59 ChEMBL 10.1021/jm301545c 10.7270/Q22R3T54 23734634 Mach, RH; Zeng, C; Hawkins, WG Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137626&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10392655 104027769 CHEMBL59713 ZINC26162325 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50083286 COc1cc2CCN(CCCCNC(=O)c3cc(Br)cc(OC)c3OC)Cc2cc1OC InChI=1S/C24H31BrN2O5/c1-29-20-11-16-7-10-27(15-17(16)12-21(20)30-2)9-6-5-8-26-24(28)19-13-18(25)14-22(31-3)23(19)32-4/h11-14H,5-10,15H2,1-4H3,(H,26,28) UNYNHWPKQAKANT-UHFFFAOYSA-N 50137618 5-Bromo-N-[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-butyl]-2,3-dimethoxy-benzamide::5-bromo-N-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-2,3-dimethoxybenzamide::CHEMBL291439 D(2) dopamine receptor Homo sapiens 2200 ChEMBL 10.1021/jm301545c 10.7270/Q22R3T54 23734634 Mach, RH; Zeng, C; Hawkins, WG Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10458892 104027761 CHEMBL291439 ZINC13588503 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087149 COc1c(C)ccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C19H21NO/c1-12-7-8-14-11-16-17-13(9-10-20(16)2)5-4-6-15(17)18(14)19(12)21-3/h4-8,16H,9-11H2,1-3H3/t16-/m1/s1 AERBGYMOICIFRM-MRXNPFEDSA-N 50052848 (R)-11-Methoxy-6,10-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL332178 D(2) dopamine receptor Homo sapiens 248 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333837 103949588 CHEMBL332178 ZINC13757589 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087155 COc1c(ccc2C[C@H]3N(C)CCc4cccc(c34)-c12)-c1ccco1 InChI=1S/C22H21NO2/c1-23-11-10-14-5-3-6-17-20(14)18(23)13-15-8-9-16(19-7-4-12-25-19)22(24-2)21(15)17/h3-9,12,18H,10-11,13H2,1-2H3/t18-/m1/s1 QMTSFMDPFYQGDZ-GOSISDBHSA-N 50052845 (R)-10-Furan-2-yl-11-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL119150 D(2) dopamine receptor Homo sapiens 582 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10496727 103949585 CHEMBL119150 ZINC13757593 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087159 COc1c(OS(=O)(=O)C(F)(F)F)ccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C19H18F3NO4S/c1-23-9-8-11-4-3-5-13-16(11)14(23)10-12-6-7-15(18(26-2)17(12)13)27-28(24,25)19(20,21)22/h3-7,14H,8-10H2,1-2H3/t14-/m1/s1 LJVSVAFPJCZZNX-CQSZACIVSA-N 50052853 CHEMBL334116::Trifluoro-methanesulfonic acid (R)-11-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl ester D(2) dopamine receptor Homo sapiens 1040 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15677951 103949593 CHEMBL334116 ZINC36187810 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087161 CCc1ccc2C[C@H]3N(C)CCc4cccc(c34)-c2c1O InChI=1S/C19H21NO/c1-3-12-7-8-14-11-16-17-13(9-10-20(16)2)5-4-6-15(17)18(14)19(12)21/h4-8,16,21H,3,9-11H2,1-2H3/t16-/m1/s1 IUPVUCISWBWELZ-MRXNPFEDSA-N 50052846 (R)-10-Ethyl-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL115524 D(2) dopamine receptor Homo sapiens 2050 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10826543 103949586 CHEMBL115524 ZINC13757600 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087162 CN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1 YGOZTDLAUVOPMF-OAHLLOKOSA-N 50036286 (R)-(-)-10-methyl-11-hydroxyaporphine::(R)-6,10-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL53510 D(2) dopamine receptor Homo sapiens 1070 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3082625 103944104 CHEMBL53510 ZINC00006368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087164 COc1c(C=C)ccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C20H21NO/c1-4-13-8-9-15-12-17-18-14(10-11-21(17)2)6-5-7-16(18)19(15)20(13)22-3/h4-9,17H,1,10-12H2,2-3H3/t17-/m1/s1 ZLNGLZZIHYJLNS-QGZVFWFLSA-N 50052852 (R)-11-Methoxy-6-methyl-10-vinyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL331100 D(2) dopamine receptor Homo sapiens 1750 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10732337 103949592 CHEMBL331100 ZINC13757597 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087165 CCc1ccc2C[C@H]3N(C)CCc4cccc(c34)-c2c1OC InChI=1S/C20H23NO/c1-4-13-8-9-15-12-17-18-14(10-11-21(17)2)6-5-7-16(18)19(15)20(13)22-3/h5-9,17H,4,10-12H2,1-3H3/t17-/m1/s1 PDGILEDXASXMHL-QGZVFWFLSA-N 50052858 (R)-10-Ethyl-11-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL331005 D(2) dopamine receptor Homo sapiens 411.0 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10637496 103949598 CHEMBL331005 ZINC13757599 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087166 CC(C)N1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 InChI=1S/C20H23NO/c1-12(2)21-10-9-14-5-4-6-16-18(14)17(21)11-15-8-7-13(3)20(22)19(15)16/h4-8,12,17,22H,9-11H2,1-3H3/t17-/m1/s1 JQFYCRLNYBLZGP-QGZVFWFLSA-N 50052857 (R)-6-Isopropyl-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL435779 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10851283 103949597 CHEMBL435779 ZINC13757610 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087168 Cc1ccc2C[C@H]3N(Cc4ccccc4)CCc4cccc(c34)-c2c1O InChI=1S/C24H23NO/c1-16-10-11-19-14-21-22-18(8-5-9-20(22)23(19)24(16)26)12-13-25(21)15-17-6-3-2-4-7-17/h2-11,21,26H,12-15H2,1H3/t21-/m1/s1 GWXIMTBMRWMHCD-OAQYLSRUSA-N 50052861 (R)-6-Benzyl-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL332771 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593347 103949601 CHEMBL332771 ZINC13757605 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087171 COc1c(C)ccc2C[C@H]3N(Cc4ccccc4)CCc4cccc(c34)-c12 InChI=1S/C25H25NO/c1-17-11-12-20-15-22-23-19(9-6-10-21(23)24(20)25(17)27-2)13-14-26(22)16-18-7-4-3-5-8-18/h3-12,22H,13-16H2,1-2H3/t22-/m1/s1 REHZDUZJCOTDRK-JOCHJYFZSA-N 50052860 (R)-6-Benzyl-11-methoxy-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL119223 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10713210 103949600 CHEMBL119223 ZINC13757603 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087173 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 41.9 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087178 COc1c(C)ccc2C[C@H]3N(CCc4cccc(c34)-c12)C(C)C InChI=1S/C21H25NO/c1-13(2)22-11-10-15-6-5-7-17-19(15)18(22)12-16-9-8-14(3)21(23-4)20(16)17/h5-9,13,18H,10-12H2,1-4H3/t18-/m1/s1 LARDWCCMZDLNEL-GOSISDBHSA-N 50052847 (R)-6-Isopropyl-11-methoxy-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL332490 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10566689 103949587 CHEMBL332490 ZINC13757609 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087180 Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O InChI=1S/C17H17NO/c1-10-5-6-12-9-14-15-11(7-8-18-14)3-2-4-13(15)16(12)17(10)19/h2-6,14,18-19H,7-9H2,1H3/t14-/m1/s1 MNRGHKYZSUNTQE-CQSZACIVSA-N 50052859 (R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL116367 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264172 103949599 CHEMBL116367 ZINC13757608 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087184 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(OS(=O)(=O)C(F)(F)F)c(OC)c-31 InChI=1S/C21H22F3NO4S/c1-3-10-25-11-9-13-5-4-6-15-18(13)16(25)12-14-7-8-17(20(28-2)19(14)15)29-30(26,27)21(22,23)24/h4-8,16H,3,9-12H2,1-2H3/t16-/m1/s1 VFZQJEHONJLING-MRXNPFEDSA-N 50052849 CHEMBL119900::Trifluoro-methanesulfonic acid (R)-11-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl ester D(2) dopamine receptor Homo sapiens 403.0 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052849&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10527118 103949589 CHEMBL119900 ZINC36187806 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087185 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 InChI=1S/C20H23NO/c1-3-10-21-11-9-14-5-4-6-16-18(14)17(21)12-15-8-7-13(2)20(22)19(15)16/h4-8,17,22H,3,9-12H2,1-2H3/t17-/m1/s1 OJGAXSYOOYSPGN-QGZVFWFLSA-N 50052851 (R)-10-Methyl-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119593 D(2) dopamine receptor Homo sapiens 249 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10613676 103949591 CHEMBL119593 ZINC13757602 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087188 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(OC)c-31 InChI=1S/C21H25NO/c1-4-11-22-12-10-15-6-5-7-17-19(15)18(22)13-16-9-8-14(2)21(23-3)20(16)17/h5-9,18H,4,10-13H2,1-3H3/t18-/m1/s1 SCCGREHYRSZMPG-GOSISDBHSA-N 50052856 (R)-11-Methoxy-10-methyl-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL118771 D(2) dopamine receptor Homo sapiens 238 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10757141 103949596 CHEMBL118771 ZINC13757601 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087193 COc1c(C)ccc2C[C@H]3NCCc4cccc(c34)-c12 InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19-15)4-3-5-14(16)17(13)18(11)20-2/h3-7,15,19H,8-10H2,1-2H3/t15-/m1/s1 PTLXBYXMMYOTFF-OAHLLOKOSA-N 50052855 (R)-11-Methoxy-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL117730 D(2) dopamine receptor Homo sapiens 4710 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10515835 103949595 CHEMBL117730 ZINC13757607 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087194 CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1 PCGXWSCASZVBJT-CQSZACIVSA-N 50016013 (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119455::R-(-)-11-hydroxy-aporphine D(2) dopamine receptor Homo sapiens 58.5 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015045 103927694 CHEMBL119455 ZINC00002530 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087198 CN1CCc2cccc-3c2[C@H]1Cc1ccc(-c2ccccc2)c(O)c-31 InChI=1S/C23H21NO/c1-24-13-12-16-8-5-9-19-21(16)20(24)14-17-10-11-18(23(25)22(17)19)15-6-3-2-4-7-15/h2-11,20,25H,12-14H2,1H3/t20-/m1/s1 VEPWAMNFYDUZFF-HXUWFJFHSA-N 50052850 (R)-6-Methyl-10-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119577 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44344506 103949590 CHEMBL119577 ZINC13757590 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087203 CN1CCc2cccc-3c2[C@H]1Cc1ccc(C(C)=O)c(O)c-31 InChI=1S/C19H19NO2/c1-11(21)14-7-6-13-10-16-17-12(8-9-20(16)2)4-3-5-15(17)18(13)19(14)22/h3-7,16,22H,8-10H2,1-2H3/t16-/m1/s1 QAUPWEHLWVIYLG-MRXNPFEDSA-N 50052854 1-((R)-11-Hydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)-ethanone::CHEMBL326159 D(2) dopamine receptor Homo sapiens 2760 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10803661 103949594 CHEMBL326159 ZINC13757595 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087204 COc1c(ccc2C[C@H]3N(C)CCc4cccc(c34)-c12)C(C)=O InChI=1S/C20H21NO2/c1-12(22)15-8-7-14-11-17-18-13(9-10-21(17)2)5-4-6-16(18)19(14)20(15)23-3/h4-8,17H,9-11H2,1-3H3/t17-/m1/s1 RXDUVKIICDGRRM-QGZVFWFLSA-N 50052862 1-((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)-ethanone::CHEMBL324372 D(2) dopamine receptor Homo sapiens 2980 ChEMBL 10.1021/jm960188q 10.7270/Q2XW4HXS 8784447 Hedberg, MH; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10518820 103949602 CHEMBL324372 ZINC13757594 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087208 CN1CCc2cccc-3c2[C@H]1Cc1cccc(C=C)c-31 InChI=1S/C19H19N/c1-3-13-6-4-8-15-12-17-19-14(10-11-20(17)2)7-5-9-16(19)18(13)15/h3-9,17H,1,10-12H2,2H3/t17-/m1/s1 YMOFDQWTDIMQMZ-QGZVFWFLSA-N 50052863 (R)-6-Methyl-11-vinyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL119656 D(2) dopamine receptor Homo sapiens 177 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10849018 103949603 CHEMBL119656 ZINC13757614 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087216 CN1CCc2cccc-3c2[C@H]1Cc1cccc(C(N)=O)c-31 InChI=1S/C18H18N2O/c1-20-9-8-11-4-2-6-13-16-12(10-15(20)17(11)13)5-3-7-14(16)18(19)21/h2-7,15H,8-10H2,1H3,(H2,19,21)/t15-/m1/s1 DUINJXQXGUDXQC-OAHLLOKOSA-N 50052868 (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-11-carboxylic acid amide::CHEMBL324073 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052868&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684005 103949608 CHEMBL324073 ZINC13757619 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087217 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2ccccc2)c-31 InChI=1S/C23H21N/c1-24-14-13-17-9-5-12-20-22-18(15-21(24)23(17)20)10-6-11-19(22)16-7-3-2-4-8-16/h2-12,21H,13-15H2,1H3/t21-/m1/s1 TVYKKVMHDGSECW-OAQYLSRUSA-N 50052869 (R)-6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL25924 D(2) dopamine receptor Homo sapiens 233 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10064053 103949609 CHEMBL25924 ZINC13757621 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087218 COc1ccccc1-c1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C24H23NO/c1-25-14-13-16-7-5-11-20-23-17(15-21(25)24(16)20)8-6-10-19(23)18-9-3-4-12-22(18)26-2/h3-12,21H,13-15H2,1-2H3/t21-/m1/s1 LEQQCMUWPDWHHF-OAQYLSRUSA-N 50052870 (R)-11-(2-Methoxy-phenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL333085 D(2) dopamine receptor Homo sapiens 1330 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10736014 103949610 CHEMBL333085 ZINC13757623 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087222 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Homo sapiens 12.7 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087223 CC(C)N1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-12(2)20-10-9-13-5-3-7-15-18(13)16(20)11-14-6-4-8-17(21)19(14)15/h3-8,12,16,21H,9-11H2,1-2H3/t16-/m1/s1 UAKHJBZICLWRCE-MRXNPFEDSA-N 50052872 (R)-6-Isopropyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL333725 D(2) dopamine receptor Homo sapiens 1010 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10588763 103949612 CHEMBL333725 ZINC13757632 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087224 Oc1cccc2C[C@H]3NCCc4cccc(c34)-c12 InChI=1S/C16H15NO/c18-14-6-2-4-11-9-13-15-10(7-8-17-13)3-1-5-12(15)16(11)14/h1-6,13,17-18H,7-9H2/t13-/m1/s1 MHKSWTAPYIFAAP-CYBMUJFWSA-N 50052873 (R)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL332332 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052873&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10490043 103949613 CHEMBL332332 ZINC03651666 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087225 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 41.9 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087235 CN1CCc2cccc3-c4ccccc4C[C@@H]1c23 InChI=1S/C17H17N/c1-18-10-9-12-6-4-8-15-14-7-3-2-5-13(14)11-16(18)17(12)15/h2-8,16H,9-11H2,1H3/t16-/m1/s1 BZKUYNBAFQJRDM-MRXNPFEDSA-N 50052865 (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL281357 D(2) dopamine receptor Homo sapiens 527 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10421583 103949605 35643 CHEMBL281357 ZINC02386800 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087238 COc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C18H19NO/c1-19-10-9-12-5-3-7-14-17(12)15(19)11-13-6-4-8-16(20-2)18(13)14/h3-8,15H,9-11H2,1-2H3/t15-/m1/s1 HJSGUUPPOBQDHU-OAHLLOKOSA-N 50016007 (R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL117841 D(2) dopamine receptor Homo sapiens 551 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016007&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13994412 103927688 CHEMBL117841 ZINC13757611 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087239 COc1cccc2C[C@H]3NCCc4cccc(c34)-c12 InChI=1S/C17H17NO/c1-19-15-7-3-5-12-10-14-16-11(8-9-18-14)4-2-6-13(16)17(12)15/h2-7,14,18H,8-10H2,1H3/t14-/m1/s1 WJLQHAGLYICAJM-CQSZACIVSA-N 50052871 (R)-11-Methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL119132 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10705905 103949611 CHEMBL119132 ZINC13757627 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087243 CN1CCc2cccc-3c2[C@H]1Cc1cccc(C#N)c-31 InChI=1S/C18H16N2/c1-20-9-8-12-4-3-7-15-17-13(10-16(20)18(12)15)5-2-6-14(17)11-19/h2-7,16H,8-10H2,1H3/t16-/m1/s1 IOWHLLZHQXIVJB-MRXNPFEDSA-N 50052877 (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-11-carbonitrile::CHEMBL115969 D(2) dopamine receptor Homo sapiens 183 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052877&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10825256 103949617 CHEMBL115969 ZINC13757617 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087245 CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31 InChI=1S/C18H19N/c1-12-5-3-7-14-11-16-18-13(9-10-19(16)2)6-4-8-15(18)17(12)14/h3-8,16H,9-11H2,1-2H3/t16-/m1/s1 IVHTVHNCRZDRRG-MRXNPFEDSA-N 50052867 (R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL27940 D(2) dopamine receptor Homo sapiens 201 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10610641 103949607 CHEMBL27940 ZINC13757612 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087252 COc1cccc2C[C@H]3N(CCc4cccc(c34)-c12)C(C)C InChI=1S/C20H23NO/c1-13(2)21-11-10-14-6-4-8-16-19(14)17(21)12-15-7-5-9-18(22-3)20(15)16/h4-9,13,17H,10-12H2,1-3H3/t17-/m1/s1 SWVCTRVZUDUHBL-QGZVFWFLSA-N 50052878 (R)-6-Isopropyl-11-methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL115402 D(2) dopamine receptor Homo sapiens 1000 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052878&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10827592 103949618 CHEMBL115402 ZINC13757630 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087254 CN1CCc2cccc-3c2[C@H]1Cc1cccc(C(C)=O)c-31 InChI=1S/C19H19NO/c1-12(21)15-7-4-6-14-11-17-19-13(9-10-20(17)2)5-3-8-16(19)18(14)15/h3-8,17H,9-11H2,1-2H3/t17-/m1/s1 ZAAVRXQHDCCUQJ-QGZVFWFLSA-N 50052879 1-((R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-ethanone::CHEMBL333134 D(2) dopamine receptor Homo sapiens 311 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052879&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10683943 103949619 CHEMBL333134 ZINC13757613 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087250 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OC)c-31 InChI=1S/C20H23NO/c1-3-11-21-12-10-14-6-4-8-16-19(14)17(21)13-15-7-5-9-18(22-2)20(15)16/h4-9,17H,3,10-13H2,1-2H3/t17-/m1/s1 PZJGVCFSNKRINT-QGZVFWFLSA-N 50052876 (R)-11-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL119154 D(2) dopamine receptor Homo sapiens 826 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052876&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13922231 103949616 CHEMBL119154 ZINC05833991 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087259 CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1 PCGXWSCASZVBJT-CQSZACIVSA-N 50016013 (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119455::R-(-)-11-hydroxy-aporphine D(2) dopamine receptor Homo sapiens 58.5 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015045 103927694 CHEMBL119455 ZINC00002530 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087261 COc1cccc2C[C@H]3N(Cc4ccccc4)CCc4cccc(c34)-c12 InChI=1S/C24H23NO/c1-26-22-12-6-10-19-15-21-23-18(9-5-11-20(23)24(19)22)13-14-25(21)16-17-7-3-2-4-8-17/h2-12,21H,13-16H2,1H3/t21-/m1/s1 PBBOPFQFJAEPAI-OAQYLSRUSA-N 50052874 (R)-6-Benzyl-11-methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL119401 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10712278 103949614 CHEMBL119401 ZINC13757626 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087262 CCc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C19H21N/c1-3-13-6-4-8-15-12-17-19-14(10-11-20(17)2)7-5-9-16(19)18(13)15/h4-9,17H,3,10-12H2,1-2H3/t17-/m1/s1 KCQGEEQDLXFPPZ-QGZVFWFLSA-N 50052864 (R)-11-Ethyl-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL118254 D(2) dopamine receptor Homo sapiens 79.2 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10061323 103949604 CHEMBL118254 ZINC13757616 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087268 CN1CCc2cccc-3c2[C@H]1Cc1cccc(OS(=O)(=O)C(F)(F)F)c-31 InChI=1S/C18H16F3NO3S/c1-22-9-8-11-4-2-6-13-16(11)14(22)10-12-5-3-7-15(17(12)13)25-26(23,24)18(19,20)21/h2-7,14H,8-10H2,1H3/t14-/m1/s1 AZFCGGUCEYWFCK-CQSZACIVSA-N 50052875 CHEMBL333836::Trifluoro-methanesulfonic acid (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester D(2) dopamine receptor Homo sapiens 195 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052875&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786190 103949615 CHEMBL333836 ZINC36187803 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50087269 Oc1cccc2C[C@H]3N(Cc4ccccc4)CCc4cccc(c34)-c12 InChI=1S/C23H21NO/c25-21-11-5-9-18-14-20-22-17(8-4-10-19(22)23(18)21)12-13-24(20)15-16-6-2-1-3-7-16/h1-11,20,25H,12-15H2/t20-/m1/s1 JYDCTFIFEUMCFH-HXUWFJFHSA-N 50052866 (R)-6-Benzyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119384 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm960189i 10.7270/Q2T43S6S 8784448 Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10687667 103949606 CHEMBL119384 ZINC27105999 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50086496 Nc1ccc(cc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-11-9-18(10-12-21)6-4-5-15-23-16-13-20(14-17-23)19-7-2-1-3-8-19/h1-3,7-13H,5,14-17,22H2 STFIELBPKGAKNX-UHFFFAOYSA-N 50052531 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL108531 D(2) dopamine receptor Homo sapiens 0.5 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425024 103949383 CHEMBL108531 ZINC01533849 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50086504 Nc1ccc(nc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c21-19-9-10-20(22-16-19)8-4-5-13-23-14-11-18(12-15-23)17-6-2-1-3-7-17/h1-3,6-7,9-11,16H,5,12-15,21H2 LPLZFZAIOWVRTJ-UHFFFAOYSA-N 50052532 6-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-3-ylamine::CHEMBL109101 D(2) dopamine receptor Homo sapiens 1.3 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086348 103949384 CHEMBL109101 ZINC01533848 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50086512 Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 HGEYJZMMUGWEOT-UHFFFAOYSA-N 50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole D(2) dopamine receptor Homo sapiens 0.37 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 219050 103916479 48558 CHEMBL431367 52 ZINC01548439 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50086533 C(CN1CCC(=CC1)c1ccccc1)C#Cc1cccnc1 InChI=1S/C20H20N2/c1-2-9-19(10-3-1)20-11-15-22(16-12-20)14-5-4-7-18-8-6-13-21-17-18/h1-3,6,8-11,13,17H,5,12,14-16H2 QNTNWSQRMBFBSH-UHFFFAOYSA-N 50052528 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL108463 D(2) dopamine receptor Homo sapiens 1.7 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10827222 103949380 CHEMBL108463 ZINC01533844 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50086539 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccncc1 InChI=1S/C20H20N2/c1-2-7-19(8-3-1)20-11-16-22(17-12-20)15-5-4-6-18-9-13-21-14-10-18/h1-3,7-11,13-14H,5,12,15-17H2 VPUYNZMAEQVXFX-UHFFFAOYSA-N 50052533 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL110489 D(2) dopamine receptor Homo sapiens 1 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684789 103949385 CHEMBL110489 ZINC01533847 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50086542 Nc1ccc(cn1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c21-20-10-9-17(16-22-20)6-4-5-13-23-14-11-19(12-15-23)18-7-2-1-3-8-18/h1-3,7-11,16H,5,12-15H2,(H2,21,22) KAPNJGZVRYPTJW-UHFFFAOYSA-N 50052530 5-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-2-ylamine::CHEMBL109063 D(2) dopamine receptor Homo sapiens 0.5 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357631 103949382 CHEMBL109063 ZINC26941584 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50086543 Nc1cccc(c1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-11-6-8-18(17-21)7-4-5-14-23-15-12-20(13-16-23)19-9-2-1-3-10-19/h1-3,6,8-12,17H,5,13-16,22H2 KHTVRVDYYAMNRK-UHFFFAOYSA-N 50052535 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL108532 D(2) dopamine receptor Homo sapiens 9.8 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780717 103949387 CHEMBL108532 ZINC13757298 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090226 Fc1cccc2C[C@@H](CCc12)NCCCCN1C(=O)CC2(CCCC2)CC1=O InChI=1S/C23H31FN2O2/c24-20-7-5-6-17-14-18(8-9-19(17)20)25-12-3-4-13-26-21(27)15-23(16-22(26)28)10-1-2-11-23/h5-7,18,25H,1-4,8-16H2/t18-/m1/s1 GVWRDZDVMQQZBK-GOSISDBHSA-N 50054333 8-[4-((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL139089 D(2) dopamine receptor Homo sapiens 37 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620194 103950983 CHEMBL139089 ZINC12356266 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090231 CCCN(Cc1ccccc1)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C20H24FN/c1-2-13-22(15-16-7-4-3-5-8-16)18-11-12-19-17(14-18)9-6-10-20(19)21/h3-10,18H,2,11-15H2,1H3/t18-/m1/s1 IZRKKTGXKLIJDE-GOSISDBHSA-N 50054337 Benzyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL65847 D(2) dopamine receptor Homo sapiens 415.0 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402380 103950987 CHEMBL65847 ZINC13760017 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50091248 COc1ccc(CNC(=O)\C=C\c2ccc3[nH]cc(CCN(C)C)c3c2)cc1 InChI=1S/C23H27N3O2/c1-26(2)13-12-19-16-24-22-10-6-17(14-21(19)22)7-11-23(27)25-15-18-4-8-20(28-3)9-5-18/h4-11,14,16,24H,12-13,15H2,1-3H3,(H,25,27)/b11-7+ LBVZWEWTNUDWNS-YRNVUSSQSA-N 50054764 (E)-3-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-(4-methoxy-benzyl)-acrylamide::CHEMBL344127 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm9604890 10.7270/Q2R210GS 8941384 Barf, TA; de Boer, P; Wikstrom, H; Peroutka, SJ; Swensson, K; Ennis, MD; Ghazal, NB; McGuire, JC; Smith, MW University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6160690 103951349 CHEMBL344127 ZINC00840177 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090238 CCCN(CCC)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C16H24FN/c1-3-10-18(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)17/h5-7,14H,3-4,8-12H2,1-2H3/t14-/m1/s1 WFENTJXFRAVXHY-CQSZACIVSA-N 50053670 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine; hydrochloride::CHEMBL541858::CHEMBL69985 D(2) dopamine receptor Homo sapiens 201 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10729313 103950349 CHEMBL69985CHEMBL541858 ZINC13759323 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090243 CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C26H37FN2O2/c1-2-14-28(21-10-11-22-20(17-21)8-7-9-23(22)27)15-5-6-16-29-24(30)18-26(19-25(29)31)12-3-4-13-26/h7-9,21H,2-6,10-19H2,1H3/t21-/m1/s1 BYVRVQNZFICZEB-OAQYLSRUSA-N 50054342 8-{4-[((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL138998 D(2) dopamine receptor Homo sapiens 4.94 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10502670 103950992 CHEMBL138998 ZINC13760023 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090247 Fc1cccc2C[C@@H](CCc12)NCc1ccccc1 InChI=1S/C17H18FN/c18-17-8-4-7-14-11-15(9-10-16(14)17)19-12-13-5-2-1-3-6-13/h1-8,15,19H,9-12H2/t15-/m1/s1 QBTYVNHGXHWAKS-OAHLLOKOSA-N 50054339 Benzyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine::CHEMBL141537 D(2) dopamine receptor Homo sapiens 2830 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10515180 103950989 CHEMBL141537 ZINC12355962 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090250 CCCN(C(C)C)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C16H24FN/c1-4-10-18(12(2)3)14-8-9-15-13(11-14)6-5-7-16(15)17/h5-7,12,14H,4,8-11H2,1-3H3/t14-/m1/s1 LHEQMLMJFATZEM-CQSZACIVSA-N 50054335 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-isopropyl-propyl-amine::CHEMBL345087 D(2) dopamine receptor Homo sapiens 1530 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10586728 103950985 CHEMBL345087 ZINC13760021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090251 CCCCN[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C14H20FN/c1-2-3-9-16-12-7-8-13-11(10-12)5-4-6-14(13)15/h4-6,12,16H,2-3,7-10H2,1H3/t12-/m1/s1 VXPJDPSEYZZZEM-GFCCVEGCSA-N 50054341 Butyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine::CHEMBL141511 D(2) dopamine receptor Homo sapiens 790 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10560954 103950991 CHEMBL141511 ZINC13760020 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090255 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 572 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090256 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.66 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090260 N[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C10H12FN/c11-10-3-1-2-7-6-8(12)4-5-9(7)10/h1-3,8H,4-6,12H2/t8-/m1/s1 VCSRUJJOQUHUJC-MRVPVSSYSA-N 50054334 (R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamine::CHEMBL138792 D(2) dopamine receptor Homo sapiens 585 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10725712 103950984 CHEMBL138792 ZINC08699656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090263 CC(C)N[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C13H18FN/c1-9(2)15-11-6-7-12-10(8-11)4-3-5-13(12)14/h3-5,9,11,15H,6-8H2,1-2H3/t11-/m1/s1 PEALWHNJZNZNMZ-LLVKDONJSA-N 50054340 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-isopropyl-amine::CHEMBL342630 D(2) dopamine receptor Homo sapiens 2450 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10608413 103950990 CHEMBL342630 ZINC13760019 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090264 CCCCN(CCC)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C17H26FN/c1-3-5-12-19(11-4-2)15-9-10-16-14(13-15)7-6-8-17(16)18/h6-8,15H,3-5,9-13H2,1-2H3/t15-/m1/s1 VYCKVQISRHCOOL-OAHLLOKOSA-N 50054338 Butyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL141510 D(2) dopamine receptor Homo sapiens 210 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10355406 103950988 CHEMBL141510 ZINC13760022 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50090267 CCCN[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C13H18FN/c1-2-8-15-11-6-7-12-10(9-11)4-3-5-13(12)14/h3-5,11,15H,2,6-9H2,1H3/t11-/m1/s1 PAFOMDPWWHFCGE-LLVKDONJSA-N 50054336 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL139345 D(2) dopamine receptor Homo sapiens 167 ChEMBL 10.1021/jm960350p 10.7270/Q21G0KCQ 8893836 Malmberg, A; Hook, BB; Johansson, AM; Hacksell, U Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10679847 103950986 CHEMBL139345 ZINC13760018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093053 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 4.8 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093055 C(N1CCN(CC1)c1ccccc1)c1cnc([nH]1)-c1ccccc1 InChI=1S/C20H22N4/c1-3-7-17(8-4-1)20-21-15-18(22-20)16-23-11-13-24(14-12-23)19-9-5-2-6-10-19/h1-10,15H,11-14,16H2,(H,21,22) PORLBUSMWVWYQB-UHFFFAOYSA-N 50055810 1-Phenyl-4-(2-phenyl-3H-imidazol-4-ylmethyl)-piperazine::1-phenyl-4-((2-phenyl-1H-imidazol-4-yl)methyl)piperazine::CHEMBL103871 D(2) dopamine receptor Homo sapiens 254 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3691783 103952292 CHEMBL103871 ZINC13760732 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093056 C(N1CCN(CC1)c1ncccn1)c1cnc([nH]1)-c1ccccc1 InChI=1S/C18H20N6/c1-2-5-15(6-3-1)17-21-13-16(22-17)14-23-9-11-24(12-10-23)18-19-7-4-8-20-18/h1-8,13H,9-12,14H2,(H,21,22) OTVQCHUIPJYASM-UHFFFAOYSA-N 85136 CAS_188942::CHEMBL103772::NGD 94-1::NSC_188942 D(2) dopamine receptor Homo sapiens 2250 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 188942 136351236 CHEMBL103772 979 ZINC26817456 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093057 C(N1CCN(CC1)c1ccccn1)c1cnc([nH]1)-c1ccccc1 InChI=1S/C19H21N5/c1-2-6-16(7-3-1)19-21-14-17(22-19)15-23-10-12-24(13-11-23)18-8-4-5-9-20-18/h1-9,14H,10-13,15H2,(H,21,22) RGUPPVFDUJOBQL-UHFFFAOYSA-N 50055808 1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-2-yl-piperazine::CHEMBL99967 D(2) dopamine receptor Homo sapiens 2190 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2812861 103952290 CHEMBL99967 ZINC13760733 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093059 C(N1CCN(CC1)c1cnccn1)c1cnc([nH]1)-c1ccccc1 InChI=1S/C18H20N6/c1-2-4-15(5-3-1)18-21-12-16(22-18)14-23-8-10-24(11-9-23)17-13-19-6-7-20-17/h1-7,12-13H,8-11,14H2,(H,21,22) GRRGOFXERNJCAY-UHFFFAOYSA-N 50055813 4-(2-Phenyl-3H-imidazol-4-ylmethyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl::CHEMBL440511 D(2) dopamine receptor Homo sapiens >4130 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10639430 103952295 CHEMBL440511 ZINC13760735 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093064 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 254 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093067 Cc1nc([nH]c1CN1CCN(CC1)c1ncccn1)-c1ccccc1 InChI=1S/C19H22N6/c1-15-17(23-18(22-15)16-6-3-2-4-7-16)14-24-10-12-25(13-11-24)19-20-8-5-9-21-19/h2-9H,10-14H2,1H3,(H,22,23) WVAKMWHEKNXRHK-UHFFFAOYSA-N 50055807 2-[4-(5-Methyl-2-phenyl-3H-imidazol-4-ylmethyl)-piperazin-1-yl]-pyrimidine::CHEMBL415014 D(2) dopamine receptor Homo sapiens 1440 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10735463 103952289 CHEMBL415014 ZINC13760737 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093069 C(N1CCN(CC1)c1ccncn1)c1cnc([nH]1)-c1ccccc1 InChI=1S/C18H20N6/c1-2-4-15(5-3-1)18-20-12-16(22-18)13-23-8-10-24(11-9-23)17-6-7-19-14-21-17/h1-7,12,14H,8-11,13H2,(H,20,22) FLGOCJKEWNMJFU-UHFFFAOYSA-N 50055814 4-[4-(2-Phenyl-3H-imidazol-4-ylmethyl)-piperazin-1-yl]-pyrimidine::CHEMBL102599 D(2) dopamine receptor Homo sapiens >4130 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10543696 103952296 CHEMBL102599 ZINC13760736 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093075 C(N1CCN(CC1)c1ccncc1)c1cnc([nH]1)-c1ccccc1 InChI=1S/C19H21N5/c1-2-4-16(5-3-1)19-21-14-17(22-19)15-23-10-12-24(13-11-23)18-6-8-20-9-7-18/h1-9,14H,10-13,15H2,(H,21,22) KUSCFKVIWPJIJJ-UHFFFAOYSA-N 50055809 1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-4-yl-piperazine::CHEMBL317250 D(2) dopamine receptor Homo sapiens >3500 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10757990 103952291 CHEMBL317250 ZINC20535876 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50093079 C(N1CCN(CC1)c1cccnc1)c1cnc([nH]1)-c1ccccc1 InChI=1S/C19H21N5/c1-2-5-16(6-3-1)19-21-13-17(22-19)15-23-9-11-24(12-10-23)18-7-4-8-20-14-18/h1-8,13-14H,9-12,15H2,(H,21,22) DDCGYKUGMMDSDD-UHFFFAOYSA-N 50055811 1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-3-yl-piperazine::CHEMBL321513 D(2) dopamine receptor Homo sapiens 296 ChEMBL 10.1021/jm960637m 10.7270/Q21C1W0V 9016321 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10495881 103952293 CHEMBL321513 ZINC13760734 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094009 CN[C@@H]1Cc2cccc3ncn(C1)c23 InChI=1S/C11H13N3/c1-12-9-5-8-3-2-4-10-11(8)14(6-9)7-13-10/h2-4,7,9,12H,5-6H2,1H3/t9-/m1/s1 BGMDLAIZBKXVQQ-SECBINFHSA-N 50056442 (R)-5,6-Dihydro-4H-imidazo[4,5,1-ij]quinolin-5-yl-methyl-amine::CHEMBL348285 D(2) dopamine receptor Homo sapiens 355 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10535587 103952698 CHEMBL348285 ZINC12355890 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094013 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 50056445 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea::CHEMBL157138::N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea::lisuride::lisuride, (S) D(2) dopamine receptor Homo sapiens 0.5 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H8G 7WC7,7UM6,6DRX 28864 103952701 51164 CHEMBL157138 DB00589 43 ZINC03831001 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094014 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Homo sapiens 4 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094015 CCCN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C13H17N3O/c1-2-6-14-10-7-9-4-3-5-11-12(9)16(8-10)13(17)15-11/h3-5,10,14H,2,6-8H2,1H3,(H,15,17)/t10-/m1/s1 XTWUNLMHXDDOMD-SNVBAGLBSA-N 50056446 (R)-5-Propylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL434665 D(2) dopamine receptor Homo sapiens 2.5 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132955 103952702 CHEMBL434665 ZINC03785751 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094020 CN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C11H13N3O/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9/h2-4,8,12H,5-6H2,1H3,(H,13,15)/t8-/m1/s1 RKZSNTNMEFVBDT-MRVPVSSYSA-N 50056443 (R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL419792::PNU-95666E D(2) dopamine receptor Homo sapiens 9 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9818479 103952699 CHEMBL419792 3949 ZINC03960633 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094021 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 10 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094023 CN(C)[C@@H]1Cc2cccc3ncn(C1)c23 InChI=1S/C12H15N3/c1-14(2)10-6-9-4-3-5-11-12(9)15(7-10)8-13-11/h3-5,8,10H,6-7H2,1-2H3/t10-/m1/s1 SHTKKIRPSYJFRO-SNVBAGLBSA-N 50056447 (R)-5,6-Dihydro-4H-imidazo[4,5,1-ij]quinolin-5-yl-dimethyl-amine::CHEMBL345458 D(2) dopamine receptor Homo sapiens 1281 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9837094 103952703 CHEMBL345458 ZINC13761096 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094024 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Homo sapiens 7.2 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50094031 CN(C)[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C12H15N3O/c1-14(2)9-6-8-4-3-5-10-11(8)15(7-9)12(16)13-10/h3-5,9H,6-7H2,1-2H3,(H,13,16)/t9-/m1/s1 GYEMKOUGMLMNRE-SECBINFHSA-N 50056444 (R)-5-Dimethylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL422344 D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1021/jm960360q 10.7270/Q29P30R9 9057850 Heier, RF; Dolak, LA; Duncan, JN; Hyslop, DK; Lipton, MF; Martin, IJ; Mauragis, MA; Piercey, MF; Nichols, NF; Schreur, PJ; Smith, MW; Moon, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10059206 103952700 CHEMBL422344 ZINC03788021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50092959 C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C25H32N4/c1-2-6-24-22(5-1)23(19-27-24)21-10-8-20(9-11-21)12-14-28-15-17-29(18-16-28)25-7-3-4-13-26-25/h1-7,13,19-21,27H,8-12,14-18H2/t20-,21- WKRNNVUISXJKDT-MEMLXQNLSA-N 50055721 3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL423499 D(2) dopamine receptor Homo sapiens 2.8 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886609 103952203 CHEMBL423499 ZINC26575180 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098656 CCCN(CC[C@@]1(O)C[C@@H](C1)NC(=O)c1ccc2ccccc2c1)[C@H]1C[C@@H]1c1cccc(Cl)c1 InChI=1S/C29H33ClN2O2/c1-2-13-32(27-17-26(27)22-8-5-9-24(30)16-22)14-12-29(34)18-25(19-29)31-28(33)23-11-10-20-6-3-4-7-21(20)15-23/h3-11,15-16,25-27,34H,2,12-14,17-19H2,1H3,(H,31,33)/t25-,26-,27+,29+/m1/s1 XXFDUBQKUBCCOE-DIBLIPFTSA-N 50016444 CHEMBL3265065 D(2) dopamine receptor Homo sapiens 1220 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90643699 103927856 CHEMBL3265065 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098657 CCCN(CC[C@@]1(O)C[C@@H](C1)NC(=O)c1ccc2ccccc2c1)[C@H]1C[C@@H]1c1ccccc1Cl InChI=1S/C29H33ClN2O2/c1-2-14-32(27-17-25(27)24-9-5-6-10-26(24)30)15-13-29(34)18-23(19-29)31-28(33)22-12-11-20-7-3-4-8-21(20)16-22/h3-12,16,23,25,27,34H,2,13-15,17-19H2,1H3,(H,31,33)/t23-,25-,27+,29+/m1/s1 HUIZNJVXOSCZJU-UXLOVFDUSA-N 50016447 CHEMBL3265064 D(2) dopamine receptor Homo sapiens 923 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90643700 103927859 CHEMBL3265064 ZINC36272380 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098658 CCCN(CC[C@@]1(O)C[C@@H](C1)NC(=O)c1ccc2ccccc2c1)C1CC1c1ccc(Cl)cc1 InChI=1S/C29H33ClN2O2/c1-2-14-32(27-17-26(27)21-9-11-24(30)12-10-21)15-13-29(34)18-25(19-29)31-28(33)23-8-7-20-5-3-4-6-22(20)16-23/h3-12,16,25-27,34H,2,13-15,17-19H2,1H3,(H,31,33)/t25-,26?,27?,29+ KIRKSXHWZHQUBF-PGJPKGLCSA-N 50016453 CHEMBL3265063 D(2) dopamine receptor Homo sapiens 667 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90643701 103927865 CHEMBL3265063 ZINC36272384 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098684 CCCN(CC[C@@]1(O)C[C@@H](C1)NC(=O)c1ccc2ccccc2c1)[C@@H]1C[C@H]1c1ccc(Cl)cc1 InChI=1S/C29H33ClN2O2/c1-2-14-32(27-17-26(27)21-9-11-24(30)12-10-21)15-13-29(34)18-25(19-29)31-28(33)23-8-7-20-5-3-4-6-22(20)16-23/h3-12,16,25-27,34H,2,13-15,17-19H2,1H3,(H,31,33)/t25-,26-,27+,29+/m0/s1 KIRKSXHWZHQUBF-YJIPECKFSA-N 50016462 CHEMBL3265067 D(2) dopamine receptor Homo sapiens 623 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90643702 242041634 CHEMBL3265067 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098685 CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C24H28FN3O2/c1-26-18-28(21-6-3-2-4-7-21)24(23(26)30)13-16-27(17-14-24)15-5-8-22(29)19-9-11-20(25)12-10-19/h2-4,6-7,9-12H,5,8,13-18H2,1H3 QHJLPOSPWKZACG-UHFFFAOYSA-N 50004813 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one (N-methylspiperone,NMSP)::CHEMBL267932 D(2) dopamine receptor Homo sapiens 0.133000 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119146 103918360 CHEMBL267932 196 ZINC02572278 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098686 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Homo sapiens 0.086000 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098687 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Homo sapiens 13 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098688 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Homo sapiens 2.6 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098689 COc1ccccc1N1CCN(CC(O)CCNC(=O)c2ccc(cc2)-c2ccccn2)CC1 InChI=1S/C27H32N4O3/c1-34-26-8-3-2-7-25(26)31-18-16-30(17-19-31)20-23(32)13-15-29-27(33)22-11-9-21(10-12-22)24-6-4-5-14-28-24/h2-12,14,23,32H,13,15-20H2,1H3,(H,29,33) YPXXSRYKHFAWBF-UHFFFAOYSA-N 50219105 CHEMBL242644::N-(3-hydroxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-pyridin-2-ylbenzamide D(2) dopamine receptor Homo sapiens 1090 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219105&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44427831 104092475 CHEMBL242644 ZINC28711333 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50098690 OC(CCNC(=O)c1cc2ccccc2[nH]1)CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H26Cl2N4O2/c24-18-5-3-7-21(22(18)25)29-12-10-28(11-13-29)15-17(30)8-9-26-23(31)20-14-16-4-1-2-6-19(16)27-20/h1-7,14,17,27,30H,8-13,15H2,(H,26,31) NABHHUMHJIHHIX-UHFFFAOYSA-N 123850 US8748608, 34::US8748608, 34 Enantiomer A::US8748608, 34 Enantiomer B D(2) dopamine receptor Homo sapiens 746 ChEMBL 10.1021/jm401798r 10.7270/Q2BV7J5V 24848155 Chen, J; Levant, B; Jiang, C; Keck, TM; Newman, AH; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25141534 225150256 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097700 COc1ccccc1N1CCN(CNC(=O)c2ccc(C)cc2)CC1 InChI=1S/C20H25N3O2/c1-16-7-9-17(10-8-16)20(24)21-15-22-11-13-23(14-12-22)18-5-3-4-6-19(18)25-2/h3-10H,11-15H2,1-2H3,(H,21,24) YBUOJMCAVXYQBO-UHFFFAOYSA-N 50058222 CHEMBL51023::N-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-4-methyl-benzamide D(2) dopamine receptor Homo sapiens 291 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593191 103954199 CHEMBL51023 ZINC13762304 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097703 Cc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1Cl InChI=1S/C19H22ClN3O/c1-15-5-4-6-16(13-15)19(24)21-14-22-9-11-23(12-10-22)18-8-3-2-7-17(18)20/h2-8,13H,9-12,14H2,1H3,(H,21,24) ZVHOLIZEVQEFBP-UHFFFAOYSA-N 50058224 CHEMBL298166::N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-3-methyl-benzamide D(2) dopamine receptor Homo sapiens 1330 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058224&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10665101 103954201 CHEMBL298166 ZINC13762302 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097704 O=C(NCN1CCN(CC1)c1ccccc1C#N)c1ccccc1 InChI=1S/C19H20N4O/c20-14-17-8-4-5-9-18(17)23-12-10-22(11-13-23)15-21-19(24)16-6-2-1-3-7-16/h1-9H,10-13,15H2,(H,21,24) YVWOLSSJSAUBFF-UHFFFAOYSA-N 50058221 CHEMBL423659::N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-benzamide D(2) dopamine receptor Homo sapiens 4180 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9883554 103954198 CHEMBL423659 ZINC13762298 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097706 COc1ccccc1N1CCN(CNC(=O)c2ccc(Cl)cc2)CC1 InChI=1S/C19H22ClN3O2/c1-25-18-5-3-2-4-17(18)23-12-10-22(11-13-23)14-21-19(24)15-6-8-16(20)9-7-15/h2-9H,10-14H2,1H3,(H,21,24) PNUAYJRARXKVQH-UHFFFAOYSA-N 50058223 4-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide::CHEMBL49231 D(2) dopamine receptor Homo sapiens 349 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058223&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473658 103954200 CHEMBL49231 ZINC13762316 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097714 Clc1ccc(cc1)C(=O)NCN1CCN(CC1)c1ccccc1Cl InChI=1S/C18H19Cl2N3O/c19-15-7-5-14(6-8-15)18(24)21-13-22-9-11-23(12-10-22)17-4-2-1-3-16(17)20/h1-8H,9-13H2,(H,21,24) QXXSJVZBKIQIJR-UHFFFAOYSA-N 50058230 4-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide::CHEMBL296953 D(2) dopamine receptor Homo sapiens 495 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058230&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10737474 103954207 CHEMBL296953 ZINC13762318 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097721 COc1ccccc1N1CCN(CNC(=O)c2ccccc2)CC1 InChI=1S/C19H23N3O2/c1-24-18-10-6-5-9-17(18)22-13-11-21(12-14-22)15-20-19(23)16-7-3-2-4-8-16/h2-10H,11-15H2,1H3,(H,20,23) UWUCDMAWZWXZPY-UHFFFAOYSA-N 50058231 CHEMBL48807::N-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide D(2) dopamine receptor Homo sapiens 1880 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058231&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10616050 103954208 CHEMBL48807 ZINC13762294 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097723 Cc1ccc(cc1)C(=O)NCN1CCN(CC1)c1ccccc1Cl InChI=1S/C19H22ClN3O/c1-15-6-8-16(9-7-15)19(24)21-14-22-10-12-23(13-11-22)18-5-3-2-4-17(18)20/h2-9H,10-14H2,1H3,(H,21,24) AUCTYGBZIOGIIA-UHFFFAOYSA-N 50058220 CHEMBL51536::N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-methyl-benzamide D(2) dopamine receptor Homo sapiens 466.0 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058220&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617381 103954197 CHEMBL51536 ZINC13762306 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097736 Clc1ccc(cc1)C(=O)NCN1CCN(CC1)c1ccccc1C#N InChI=1S/C19H19ClN4O/c20-17-7-5-15(6-8-17)19(25)22-14-23-9-11-24(12-10-23)18-4-2-1-3-16(18)13-21/h1-8H,9-12,14H2,(H,22,25) XISJOANVKUVBAU-UHFFFAOYSA-N 50058233 4-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide::CHEMBL49876 D(2) dopamine receptor Homo sapiens 929.0 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058233&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10760638 103954210 CHEMBL49876 ZINC13762320 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097738 Cc1ccc(cc1)C(=O)NCN1CCN(CC1)c1ccccc1C#N InChI=1S/C20H22N4O/c1-16-6-8-17(9-7-16)20(25)22-15-23-10-12-24(13-11-23)19-5-3-2-4-18(19)14-21/h2-9H,10-13,15H2,1H3,(H,22,25) FJYYLTSACBJXID-UHFFFAOYSA-N 50058234 CHEMBL300956::N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-4-methyl-benzamide D(2) dopamine receptor Homo sapiens 1150 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058234&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10088259 103954211 CHEMBL300956 ZINC13762308 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097744 Clc1ccccc1N1CCN(CNC(=O)c2ccccc2)CC1 InChI=1S/C18H20ClN3O/c19-16-8-4-5-9-17(16)22-12-10-21(11-13-22)14-20-18(23)15-6-2-1-3-7-15/h1-9H,10-14H2,(H,20,23) NZCZNMGSFLEVRM-UHFFFAOYSA-N 50058227 CHEMBL298763::N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-benzamide D(2) dopamine receptor Homo sapiens 1500 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058227&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10065188 103954204 CHEMBL298763 ZINC13762296 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097746 Cc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1C#N InChI=1S/C20H22N4O/c1-16-5-4-7-17(13-16)20(25)22-15-23-9-11-24(12-10-23)19-8-3-2-6-18(19)14-21/h2-8,13H,9-12,15H2,1H3,(H,22,25) DNULYRGWTFLJQL-UHFFFAOYSA-N 50058225 CHEMBL45244::N-((4-(2-cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamide::N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-methyl-benzamide::PD-168077 D(2) dopamine receptor Homo sapiens 3740.0 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058225&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3645619 103954202 CHEMBL45244 975 ZINC25758996 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097753 Clc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1C#N InChI=1S/C19H19ClN4O/c20-17-6-3-5-15(12-17)19(25)22-14-23-8-10-24(11-9-23)18-7-2-1-4-16(18)13-21/h1-7,12H,8-11,14H2,(H,22,25) LMFZASCXAANSLM-UHFFFAOYSA-N 50058226 3-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide::CHEMBL49502 D(2) dopamine receptor Homo sapiens 897 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058226&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9975465 103954203 CHEMBL49502 ZINC13762314 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097754 COc1ccccc1N1CCN(CNC(=O)c2cccc(C)c2)CC1 InChI=1S/C20H25N3O2/c1-16-6-5-7-17(14-16)20(24)21-15-22-10-12-23(13-11-22)18-8-3-4-9-19(18)25-2/h3-9,14H,10-13,15H2,1-2H3,(H,21,24) JIXQPDNGVCMIOH-UHFFFAOYSA-N 50058232 CHEMBL296506::N-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-3-methyl-benzamide D(2) dopamine receptor Homo sapiens 835.0 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058232&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10382581 103954209 CHEMBL296506 ZINC13762300 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097759 COc1ccccc1N1CCN(CNC(=O)c2cccc(Cl)c2)CC1 InChI=1S/C19H22ClN3O2/c1-25-18-8-3-2-7-17(18)23-11-9-22(10-12-23)14-21-19(24)15-5-4-6-16(20)13-15/h2-8,13H,9-12,14H2,1H3,(H,21,24) QPKPFUJFLVQTCR-UHFFFAOYSA-N 50058228 3-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide::CHEMBL48819 D(2) dopamine receptor Homo sapiens 451.0 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058228&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10642239 103954205 CHEMBL48819 ZINC13762310 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097718 Clc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1Cl InChI=1S/C18H19Cl2N3O/c19-15-5-3-4-14(12-15)18(24)21-13-22-8-10-23(11-9-22)17-7-2-1-6-16(17)20/h1-7,12H,8-11,13H2,(H,21,24) OFDQLTVLCXEIAI-UHFFFAOYSA-N 50058229 3-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide::CHEMBL295094 D(2) dopamine receptor Homo sapiens 2420 ChEMBL 10.1021/jm970021c 10.7270/Q2DB80XX 9191952 Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058229&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10761258 103954206 CHEMBL295094 ZINC13762312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099987 COc1ccc2c3CCN(Cc4ccc(F)cc4)Cc3c(=O)oc2c1 InChI=1S/C20H18FNO3/c1-24-15-6-7-17-16-8-9-22(11-13-2-4-14(21)5-3-13)12-18(16)20(23)25-19(17)10-15/h2-7,10H,8-9,11-12H2,1H3 PLMJRPLZFUQQCS-UHFFFAOYSA-N 50059491 3-(4-Fluoro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL91273 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10759511 103955299 CHEMBL91273 ZINC13764631 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099990 COc1ccc2c3CCN(Cc4ccc(cc4)[N+]([O-])=O)Cc3c(=O)oc2c1 InChI=1S/C20H18N2O5/c1-26-15-6-7-17-16-8-9-21(12-18(16)20(23)27-19(17)10-15)11-13-2-4-14(5-3-13)22(24)25/h2-7,10H,8-9,11-12H2,1H3 HHRUJJWXMZRWIG-UHFFFAOYSA-N 50059495 8-Methoxy-3-(4-nitro-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL88296 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10570898 103955303 CHEMBL88296 ZINC13764649 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099994 Cc1ccc2c3CCN(Cc4ccc(Cl)cc4)Cc3c(=O)oc2c1 InChI=1S/C20H18ClNO2/c1-13-2-7-17-16-8-9-22(11-14-3-5-15(21)6-4-14)12-18(16)20(23)24-19(17)10-13/h2-7,10H,8-9,11-12H2,1H3 MCJPCWOSNLXXLG-UHFFFAOYSA-N 50059499 3-(4-Chloro-benzyl)-8-methyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL89921 D(2) dopamine receptor Homo sapiens 1170 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10807035 103955307 CHEMBL89921 ZINC13764626 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099996 COc1ccc2c3CCN(Cc4ccc(Cl)cc4)Cc3c(=O)oc2c1 InChI=1S/C20H18ClNO3/c1-24-15-6-7-17-16-8-9-22(11-13-2-4-14(21)5-3-13)12-18(16)20(23)25-19(17)10-15/h2-7,10H,8-9,11-12H2,1H3 LXKHTQRJWHHCDP-UHFFFAOYSA-N 50059493 3-(4-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL92373 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10450880 103955301 CHEMBL92373 ZINC26639922 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100006 COc1ccc2c3CCN(Cc4ccncc4)Cc3c(=O)oc2c1 InChI=1S/C19H18N2O3/c1-23-14-2-3-16-15-6-9-21(11-13-4-7-20-8-5-13)12-17(15)19(22)24-18(16)10-14/h2-5,7-8,10H,6,9,11-12H2,1H3 LRQWWKKYRRTJBN-UHFFFAOYSA-N 50059503 8-Methoxy-3-pyridin-4-ylmethyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL91585 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10567839 103955311 CHEMBL91585 ZINC13764652 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100010 COc1ccc2c3CCN(Cc4cccc(Cl)c4)Cc3c(=O)oc2c1 InChI=1S/C20H18ClNO3/c1-24-15-5-6-17-16-7-8-22(11-13-3-2-4-14(21)9-13)12-18(16)20(23)25-19(17)10-15/h2-6,9-10H,7-8,11-12H2,1H3 MMTKBQGOVDOJAE-UHFFFAOYSA-N 50059494 3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL90569 D(2) dopamine receptor Homo sapiens 5500 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059494&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10641955 103955302 CHEMBL90569 ZINC13764638 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100012 Oc1ccc2c3CCN(Cc4ccc(Cl)cc4)Cc3c(=O)oc2c1 InChI=1S/C19H16ClNO3/c20-13-3-1-12(2-4-13)10-21-8-7-15-16-6-5-14(22)9-18(16)24-19(23)17(15)11-21/h1-6,9,22H,7-8,10-11H2 DTSBUYTYJIUAIH-UHFFFAOYSA-N 50059505 3-(4-Chloro-benzyl)-8-hydroxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL314095 D(2) dopamine receptor Homo sapiens 2780.0 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10042972 103955313 CHEMBL314095 ZINC13764629 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100013 Cc1ccc2c3CCN(Cc4ccccc4)Cc3c(=O)oc2c1 InChI=1S/C20H19NO2/c1-14-7-8-17-16-9-10-21(12-15-5-3-2-4-6-15)13-18(16)20(22)23-19(17)11-14/h2-8,11H,9-10,12-13H2,1H3 JYTBEUORVGHEBI-UHFFFAOYSA-N 50059496 3-Benzyl-8-methyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL92489 D(2) dopamine receptor Homo sapiens 774 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059496&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995264 103955304 CHEMBL92489 ZINC26639343 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100014 COc1ccc(CN2CCc3c(C2)c(=O)oc2cc(OC)ccc32)cc1 InChI=1S/C21H21NO4/c1-24-15-5-3-14(4-6-15)12-22-10-9-17-18-8-7-16(25-2)11-20(18)26-21(23)19(17)13-22/h3-8,11H,9-10,12-13H2,1-2H3 STNPHZVHYQRIIW-UHFFFAOYSA-N 50059502 8-Methoxy-3-(4-methoxy-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL91658 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689266 103955310 CHEMBL91658 ZINC13764647 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100016 Cc1ccc2c3CCN(Cc4ccc(F)cc4)Cc3c(=O)oc2c1 InChI=1S/C20H18FNO2/c1-13-2-7-17-16-8-9-22(11-14-3-5-15(21)6-4-14)12-18(16)20(23)24-19(17)10-13/h2-7,10H,8-9,11-12H2,1H3 XEJNEGOOYXFKMN-UHFFFAOYSA-N 50059492 3-(4-Fluoro-benzyl)-8-methyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL314285 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10687362 103955300 CHEMBL314285 ZINC13764633 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100027 COc1cc2oc(=O)c3CN(Cc4ccc(Cl)cc4)CCc3c2cc1OC InChI=1S/C21H20ClNO4/c1-25-19-9-16-15-7-8-23(11-13-3-5-14(22)6-4-13)12-17(15)21(24)27-18(16)10-20(19)26-2/h3-6,9-10H,7-8,11-12H2,1-2H3 VEPYYOGIARRSSX-UHFFFAOYSA-N 50059500 3-(4-Chloro-benzyl)-8,9-dimethoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL90173 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620139 103955308 CHEMBL90173 ZINC13764623 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100028 COc1ccc2c3CCN(CCc4ccccc4)Cc3c(=O)oc2c1 InChI=1S/C21H21NO3/c1-24-16-7-8-18-17-10-12-22(11-9-15-5-3-2-4-6-15)14-19(17)21(23)25-20(18)13-16/h2-8,13H,9-12,14H2,1H3 IAWWLCSYFAOUES-UHFFFAOYSA-N 50059497 8-Methoxy-3-phenethyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL440506 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10568805 103955305 CHEMBL440506 ZINC00023435 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100038 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.6 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100040 COc1ccc2c3CCN(Cc4ccccc4)Cc3c(=O)oc2c1 InChI=1S/C20H19NO3/c1-23-15-7-8-17-16-9-10-21(12-14-5-3-2-4-6-14)13-18(16)20(22)24-19(17)11-15/h2-8,11H,9-10,12-13H2,1H3 XPBGNLUNAORHQZ-UHFFFAOYSA-N 50059507 3-Benzyl-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL328054 D(2) dopamine receptor Homo sapiens 436.0 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059507&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9883587 103955315 CHEMBL328054 ZINC13764618 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100041 COc1ccc2c3CCN(Cc4ccc(Cl)c(Cl)c4)Cc3c(=O)oc2c1 InChI=1S/C20H17Cl2NO3/c1-25-13-3-4-15-14-6-7-23(10-12-2-5-17(21)18(22)8-12)11-16(14)20(24)26-19(15)9-13/h2-5,8-9H,6-7,10-11H2,1H3 CDPWDOLVSDDBEM-UHFFFAOYSA-N 50059498 3-(3,4-Dichloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL89913 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786591 103955306 CHEMBL89913 ZINC13764641 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100042 COc1ccc2c3CCN(Cc4ccc(C)cc4)Cc3c(=O)oc2c1 InChI=1S/C21H21NO3/c1-14-3-5-15(6-4-14)12-22-10-9-17-18-8-7-16(24-2)11-20(18)25-21(23)19(17)13-22/h3-8,11H,9-10,12-13H2,1-2H3 GCSJTLWMFLOWBK-UHFFFAOYSA-N 50059504 8-Methoxy-3-(4-methyl-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL329126 D(2) dopamine receptor Homo sapiens 1170 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640530 103955312 CHEMBL329126 ZINC13764644 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100044 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 91 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100046 COc1ccc2c3CCN(Cc4ccc(cc4)C(F)(F)F)Cc3c(=O)oc2c1 InChI=1S/C21H18F3NO3/c1-27-15-6-7-17-16-8-9-25(12-18(16)20(26)28-19(17)10-15)11-13-2-4-14(5-3-13)21(22,23)24/h2-7,10H,8-9,11-12H2,1H3 APSWOEYPVXOOHK-UHFFFAOYSA-N 50059501 8-Methoxy-3-(4-trifluoromethyl-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL91938 D(2) dopamine receptor Homo sapiens 3700 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10318141 103955309 CHEMBL91938 ZINC26643666 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100047 COc1ccc2c3CCN(Cc4ccccc4)Cc3c(=O)oc2c1OC InChI=1S/C21H21NO4/c1-24-18-9-8-16-15-10-11-22(12-14-6-4-3-5-7-14)13-17(15)21(23)26-19(16)20(18)25-2/h3-9H,10-13H2,1-2H3 ITUXESRMFODXIB-UHFFFAOYSA-N 50059508 3-Benzyl-7,8-dimethoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL330100 D(2) dopamine receptor Homo sapiens 659 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10665626 103955316 CHEMBL330100 ZINC13764620 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50100048 COc1ccc2c3CCN(Cc4ccccc4Cl)Cc3c(=O)oc2c1 InChI=1S/C20H18ClNO3/c1-24-14-6-7-16-15-8-9-22(11-13-4-2-3-5-18(13)21)12-17(15)20(23)25-19(16)10-14/h2-7,10H,8-9,11-12H2,1H3 BZWZMTTVCPOVAV-UHFFFAOYSA-N 50059511 3-(2-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL91067 D(2) dopamine receptor Homo sapiens >5800 ChEMBL 10.1021/jm970170v 10.7270/Q2SF2V8X 9276014 Unangst, PC; Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10641954 103955319 CHEMBL91067 ZINC13764635 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099401 Cc1c(n[nH]c1C1=CCN(CCc2ccccc2)CC1)-c1ccccc1 InChI=1S/C23H25N3/c1-18-22(20-10-6-3-7-11-20)24-25-23(18)21-13-16-26(17-14-21)15-12-19-8-4-2-5-9-19/h2-11,13H,12,14-17H2,1H3,(H,24,25) YYWRRBMZAGSBNZ-UHFFFAOYSA-N 50059219 4-(4-Methyl-5-phenyl-1H-pyrazol-3-yl)-1-phenethyl-1,2,3,6-tetrahydro-pyridine::CHEMBL80318 D(2) dopamine receptor Homo sapiens 90 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059219&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617366 103955063 CHEMBL80318 ZINC13763858 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099404 C(Cc1ccccc1)N1CCC2(CCc3c(n[nH]c23)-c2ccccc2)CC1 InChI=1S/C24H27N3/c1-3-7-19(8-4-1)12-16-27-17-14-24(15-18-27)13-11-21-22(25-26-23(21)24)20-9-5-2-6-10-20/h1-10H,11-18H2,(H,25,26) VOWFPVSNWUSCMB-UHFFFAOYSA-N 50059220 1'-phenethyl-3-phenylspiro[2,4,5,6-tetrahydrocyclopenta[c]pyrazole-6,4'-(hexahydropyridine)]::CHEMBL311832 D(2) dopamine receptor Homo sapiens 690 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059220&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522334 103955064 CHEMBL311832 ZINC13763874 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099406 Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(CCCc2ccccc2)CC1 InChI=1S/C23H26ClN3/c24-21-10-8-19(9-11-21)22-17-23(26-25-22)20-12-15-27(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,17,20H,4,7,12-16H2,(H,25,26) NBVOTNJROVCMMX-UHFFFAOYSA-N 50059223 4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-(3-phenyl-propyl)-piperidine::CHEMBL77017 D(2) dopamine receptor Homo sapiens 560 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059223&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10738530 103955067 CHEMBL77017 ZINC13763826 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099411 Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(Cc2ccccc2Cl)CC1 InChI=1S/C21H21Cl2N3/c22-18-7-5-15(6-8-18)20-13-21(25-24-20)16-9-11-26(12-10-16)14-17-3-1-2-4-19(17)23/h1-8,13,16H,9-12,14H2,(H,24,25) LKPNIBAOVAQLNF-UHFFFAOYSA-N 50059225 1-(2-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::CHEMBL312255 D(2) dopamine receptor Homo sapiens 700 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059225&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691523 103955069 CHEMBL312255 ZINC13763823 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099414 Clc1ccc(cc1)-c1cc([nH]n1)C1CCCCN1Cc1ccccc1 InChI=1S/C21H22ClN3/c22-18-11-9-17(10-12-18)19-14-20(24-23-19)21-8-4-5-13-25(21)15-16-6-2-1-3-7-16/h1-3,6-7,9-12,14,21H,4-5,8,13,15H2,(H,23,24) HZAQPOKTYPPOTH-UHFFFAOYSA-N 50059229 1-Benzyl-2-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::CHEMBL80863 D(2) dopamine receptor Homo sapiens 3400 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059229&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831786 103955073 CHEMBL80863 ZINC13763851 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099418 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 74 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099425 C(Cc1ccccc1)N1CCC(CC1)c1cc(n[nH]1)C1CCCCC1 InChI=1S/C22H31N3/c1-3-7-18(8-4-1)11-14-25-15-12-20(13-16-25)22-17-21(23-24-22)19-9-5-2-6-10-19/h1,3-4,7-8,17,19-20H,2,5-6,9-16H2,(H,23,24) XNFZPEDEZVYDIU-UHFFFAOYSA-N 50059235 4-(5-Cyclohexyl-1H-pyrazol-3-yl)-1-phenethyl-piperidine::CHEMBL77744 D(2) dopamine receptor Homo sapiens 61 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059235&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10520941 103955079 CHEMBL77744 ZINC13763832 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099426 Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C22H24ClN3/c23-20-8-6-18(7-9-20)21-16-22(25-24-21)19-11-14-26(15-12-19)13-10-17-4-2-1-3-5-17/h1-9,16,19H,10-15H2,(H,24,25) YCDXELFFFUYKMO-UHFFFAOYSA-N 50050472 4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethyl-piperidine::4-[5-(4-Chloro-phenyl)-2H-pyrazol-3-yl]-1-phenethyl-piperidine::CHEMBL6416 D(2) dopamine receptor Homo sapiens 520 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618874 103947642 CHEMBL6416 ZINC13755887 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099428 Clc1ccc(cc1)-c1cc([nH]n1)C1CCNCC1 InChI=1S/C14H16ClN3/c15-12-3-1-10(2-4-12)13-9-14(18-17-13)11-5-7-16-8-6-11/h1-4,9,11,16H,5-8H2,(H,17,18) GELALLNTKKLQLM-UHFFFAOYSA-N 50059237 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE::4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::CHEMBL75691 D(2) dopamine receptor Homo sapiens >1800 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L02 1WAY 449126 103955081 CHEMBL75691 DB08061 ZINC20404939 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099440 Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C21H22ClN3/c22-19-8-6-17(7-9-19)20-14-21(24-23-20)18-10-12-25(13-11-18)15-16-4-2-1-3-5-16/h1-9,14,18H,10-13,15H2,(H,23,24) VCKOBAOVBZHUOW-UHFFFAOYSA-N 50059239 1-Benzyl-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::CHEMBL76090 D(2) dopamine receptor Homo sapiens 125 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059239&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594113 103955083 CHEMBL76090 ZINC00837042 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099442 Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(Cc2ccccc2)C1 InChI=1S/C20H20ClN3/c21-18-8-6-16(7-9-18)19-12-20(23-22-19)17-10-11-24(14-17)13-15-4-2-1-3-5-15/h1-9,12,17H,10-11,13-14H2,(H,22,23) HISVPUHXONHOSX-UHFFFAOYSA-N 50059238 3-(1-Benzyl-pyrrolidin-3-yl)-5-(4-chloro-phenyl)-1H-pyrazole::CHEMBL76355 D(2) dopamine receptor Homo sapiens 120 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497193 103955082 CHEMBL76355 ZINC13763856 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099445 Clc1ccc(cc1)-c1cc([nH]n1)C1CCCN(Cc2ccccc2)C1 InChI=1S/C21H22ClN3/c22-19-10-8-17(9-11-19)20-13-21(24-23-20)18-7-4-12-25(15-18)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,13,18H,4,7,12,14-15H2,(H,23,24) RKWDQZZKDQAENU-UHFFFAOYSA-N 50059232 1-Benzyl-3-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::CHEMBL80833 D(2) dopamine receptor Homo sapiens 960 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059232&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617946 103955076 CHEMBL80833 ZINC13763845 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099446 Cc1cc([nH]n1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C16H21N3/c1-13-11-16(18-17-13)15-7-9-19(10-8-15)12-14-5-3-2-4-6-14/h2-6,11,15H,7-10,12H2,1H3,(H,17,18) BRZAPKIDJOPKEJ-UHFFFAOYSA-N 50059241 1-Benzyl-4-(5-methyl-1H-pyrazol-3-yl)-piperidine::CHEMBL77015 D(2) dopamine receptor Homo sapiens 650 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10587140 103955085 CHEMBL77015 ZINC12355968 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099447 C(Cc1ccccc1)N1CCC(CC1)c1cc(n[nH]1)-c1ccccn1 InChI=1S/C21H24N4/c1-2-6-17(7-3-1)9-13-25-14-10-18(11-15-25)20-16-21(24-23-20)19-8-4-5-12-22-19/h1-8,12,16,18H,9-11,13-15H2,(H,23,24) RWEPTLSUVVSWHX-UHFFFAOYSA-N 50059218 2-[5-(1-Phenethyl-piperidin-4-yl)-2H-pyrazol-3-yl]-pyridine::CHEMBL310819 D(2) dopamine receptor Homo sapiens 860 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059218&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10688035 103955062 CHEMBL310819 ZINC13763837 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099448 CN1CCC(CC1)c1cc(n[nH]1)-c1ccc(Cl)cc1 InChI=1S/C15H18ClN3/c1-19-8-6-12(7-9-19)15-10-14(17-18-15)11-2-4-13(16)5-3-11/h2-5,10,12H,6-9H2,1H3,(H,17,18) HSWZTUYZQLIVNT-UHFFFAOYSA-N 50059236 4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-methyl-piperidine::CHEMBL80552 D(2) dopamine receptor Homo sapiens >590 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059236&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10826290 103955080 CHEMBL80552 ZINC13763815 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099450 Cc1c([nH]nc1-c1ccc(Cl)cc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C22H24ClN3/c1-16-21(18-7-9-20(23)10-8-18)24-25-22(16)19-11-13-26(14-12-19)15-17-5-3-2-4-6-17/h2-10,19H,11-15H2,1H3,(H,24,25) GWSJSKIZAIMZOZ-UHFFFAOYSA-N 50059228 1-Benzyl-4-[5-(4-chloro-phenyl)-4-methyl-1H-pyrazol-3-yl]-piperidine::CHEMBL309901 D(2) dopamine receptor Homo sapiens 200 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059228&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618875 103955072 CHEMBL309901 ZINC13763878 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099452 C(Cc1ccccc1)N1CCC(CC1)c1cc(n[nH]1)-c1cccnc1 InChI=1S/C21H24N4/c1-2-5-17(6-3-1)8-12-25-13-9-18(10-14-25)20-15-21(24-23-20)19-7-4-11-22-16-19/h1-7,11,15-16,18H,8-10,12-14H2,(H,23,24) XTZZQQZBOKCCIX-UHFFFAOYSA-N 50059231 3-[5-(1-Phenethyl-piperidin-4-yl)-2H-pyrazol-3-yl]-pyridine::CHEMBL309460 D(2) dopamine receptor Homo sapiens 900 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059231&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10688036 103955075 CHEMBL309460 ZINC13763840 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099453 Clc1ccc(CN2CCC(CC2)c2cc(on2)-c2ccc(Cl)cc2)cc1 InChI=1S/C21H20Cl2N2O/c22-18-5-1-15(2-6-18)14-25-11-9-16(10-12-25)20-13-21(26-24-20)17-3-7-19(23)8-4-17/h1-8,13,16H,9-12,14H2 IGAYGUGEWYBNRY-UHFFFAOYSA-N 50050470 1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazol-3-yl]-piperidine::CHEMBL58296 D(2) dopamine receptor Homo sapiens 160 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11794570 103947640 CHEMBL58296 ZINC13755889 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097241 FCCN1CCC(COc2ccc(cc2)C#N)CC1 InChI=1S/C15H19FN2O/c16-7-10-18-8-5-14(6-9-18)12-19-15-3-1-13(11-17)2-4-15/h1-4,14H,5-10,12H2 WCVQBSQHLZCNCS-UHFFFAOYSA-N 50058005 4-[1-(2-Fluoro-ethyl)-piperidin-4-ylmethoxy]-benzonitrile::CHEMBL46519 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10777894 103953984 CHEMBL46519 ZINC13605791 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097244 FCCN1CCC(COc2ccc(I)cc2)CC1 InChI=1S/C14H19FINO/c15-7-10-17-8-5-12(6-9-17)11-18-14-3-1-13(16)2-4-14/h1-4,12H,5-11H2 OTGUFPDUGJBGGO-UHFFFAOYSA-N 50058008 1-(2-Fluoro-ethyl)-4-(4-iodo-phenoxymethyl)-piperidine::CHEMBL45168 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058008&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10808677 103953987 CHEMBL45168 ZINC13605800 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097246 Brc1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C16H22BrNO/c17-15-3-5-16(6-4-15)19-12-14-7-9-18(10-8-14)11-13-1-2-13/h3-6,13-14H,1-2,7-12H2 SRHAQZGWTHNYNE-UHFFFAOYSA-N 50058010 4-(4-Bromo-phenoxymethyl)-1-cyclopropylmethyl-piperidine::CHEMBL46880 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058010&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290360 103953989 CHEMBL46880 ZINC13605812 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097259 [O-][N+](=O)c1ccc(OCC2CCN(Cc3ccc(F)cc3)CC2)cc1 InChI=1S/C19H21FN2O3/c20-17-3-1-15(2-4-17)13-21-11-9-16(10-12-21)14-25-19-7-5-18(6-8-19)22(23)24/h1-8,16H,9-14H2 HTYUTOAGQKZAEN-UHFFFAOYSA-N 50058013 1-(4-Fluoro-benzyl)-4-(4-nitro-phenoxymethyl)-piperidine::CHEMBL46596 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831286 103953992 CHEMBL46596 ZINC13605798 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097260 OCCN1CCC(COc2ccc(I)cc2)CC1 InChI=1S/C14H20INO2/c15-13-1-3-14(4-2-13)18-11-12-5-7-16(8-6-12)9-10-17/h1-4,12,17H,5-11H2 XHNKRIKJZZBVIE-UHFFFAOYSA-N 50058018 2-[4-(4-Iodo-phenoxymethyl)-piperidin-1-yl]-ethanol::CHEMBL46374 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10428643 103953997 CHEMBL46374 ZINC13605802 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097261 COc1cc(CCCF)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C20H29FN2O3/c1-4-10-23-11-6-8-16(23)14-22-20(24)17-12-15(7-5-9-21)13-18(25-2)19(17)26-3/h4,12-13,16H,1,5-11,14H2,2-3H3,(H,22,24)/t16-/m0/s1 OABRYNHZQBZDMG-INIZCTEOSA-N 50220541 CHEMBL392158::Fallypride::N-(((S)-1-allylpyrrolidin-2-yl)methyl)-5-(3-fluoropropyl)-2,3-dimethoxybenzamide D(2) dopamine receptor Homo sapiens 0.097000 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10021692 104093447 CHEMBL392158 ZINC06483622 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097262 FCCCN1CCC(COc2ccc(cc2)C#N)CC1 InChI=1S/C16H21FN2O/c17-8-1-9-19-10-6-15(7-11-19)13-20-16-4-2-14(12-18)3-5-16/h2-5,15H,1,6-11,13H2 KSMXCGCEJWKWOX-UHFFFAOYSA-N 50058017 4-[1-(3-Fluoro-propyl)-piperidin-4-ylmethoxy]-benzonitrile::CHEMBL2347003::CHEMBL417001 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128032 103953996 CHEMBL417001CHEMBL2347003 ZINC06092659 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097263 Fc1ccc(CN2CCC(COc3ccc(cc3)C#N)CC2)cc1 InChI=1S/C20H21FN2O/c21-19-5-1-17(2-6-19)14-23-11-9-18(10-12-23)15-24-20-7-3-16(13-22)4-8-20/h1-8,18H,9-12,14-15H2 IFUAPMVHYZVHKY-UHFFFAOYSA-N 50058012 4-[1-(4-Fluoro-benzyl)-piperidin-4-ylmethoxy]-benzonitrile::CHEMBL46559 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10805917 103953991 CHEMBL46559 ZINC13605792 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099456 Nc1nc(cc(n1)-c1ccc(Cl)cc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C22H23ClN4/c23-19-8-6-17(7-9-19)20-14-21(26-22(24)25-20)18-10-12-27(13-11-18)15-16-4-2-1-3-5-16/h1-9,14,18H,10-13,15H2,(H2,24,25,26) UZSMYCXKQUZNLV-UHFFFAOYSA-N 50059233 4-(1-Benzyl-piperidin-4-yl)-6-(4-chloro-phenyl)-pyrimidin-2-ylamine::CHEMBL78923 D(2) dopamine receptor Homo sapiens 8.6 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059233&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9951735 103955077 CHEMBL78923 ZINC00600294 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099458 C(Cc1ccccc1)N1CCC(CC1)c1cc(n[nH]1)-c1cccs1 InChI=1S/C20H23N3S/c1-2-5-16(6-3-1)8-11-23-12-9-17(10-13-23)18-15-19(22-21-18)20-7-4-14-24-20/h1-7,14-15,17H,8-13H2,(H,21,22) RQRBGNHBNQYSEI-UHFFFAOYSA-N 50059222 1-Phenethyl-4-(5-thiophen-2-yl-1H-pyrazol-3-yl)-piperidine::CHEMBL77743 D(2) dopamine receptor Homo sapiens 65 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497179 103955066 CHEMBL77743 ZINC13763834 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099460 Clc1ccc(CN2CCC(CC2)c2cc(n[nH]2)-c2ccc(Cl)cc2)cc1 InChI=1S/C21H21Cl2N3/c22-18-5-1-15(2-6-18)14-26-11-9-17(10-12-26)21-13-20(24-25-21)16-3-7-19(23)8-4-16/h1-8,13,17H,9-12,14H2,(H,24,25) YATPAHDOUJPRNV-UHFFFAOYSA-N 50050473 1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-2H-pyrazol-3-yl]-piperidine::CHEMBL61080 D(2) dopamine receptor Homo sapiens 240 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3746693 103947643 CHEMBL61080 ZINC00837039 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099463 CCc1c([nH]nc1-c1ccc(Cl)cc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C23H26ClN3/c1-2-21-22(18-8-10-20(24)11-9-18)25-26-23(21)19-12-14-27(15-13-19)16-17-6-4-3-5-7-17/h3-11,19H,2,12-16H2,1H3,(H,25,26) GJUDGMHZQOXKJL-UHFFFAOYSA-N 50059230 1-Benzyl-4-[5-(4-chloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-piperidine::CHEMBL78933 D(2) dopamine receptor Homo sapiens 35 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059230&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10595908 103955074 CHEMBL78933 ZINC13763881 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099464 CC1(CCN(Cc2ccccc2)CC1)c1cc(n[nH]1)-c1ccc(Cl)cc1 InChI=1S/C22H24ClN3/c1-22(11-13-26(14-12-22)16-17-5-3-2-4-6-17)21-15-20(24-25-21)18-7-9-19(23)10-8-18/h2-10,15H,11-14,16H2,1H3,(H,24,25) UOIRCOOXVJGCIE-UHFFFAOYSA-N 50059217 1-Benzyl-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-4-methyl-piperidine::CHEMBL80207 D(2) dopamine receptor Homo sapiens 240 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059217&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10546828 103955061 CHEMBL80207 ZINC13763872 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099471 C(Cc1ccccc1)N1CCN(CC1)c1cc(n[nH]1)-c1ccccc1 InChI=1S/C21H24N4/c1-3-7-18(8-4-1)11-12-24-13-15-25(16-14-24)21-17-20(22-23-21)19-9-5-2-6-10-19/h1-10,17H,11-16H2,(H,22,23) ZLLPRPCSBDCTBZ-UHFFFAOYSA-N 50059224 1-Phenethyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperazine::CHEMBL310985 D(2) dopamine receptor Homo sapiens >1900 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059224&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10735344 103955068 CHEMBL310985 ZINC13763861 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099475 Cc1c([nH]nc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C23H26ClN3/c1-17-22(19-7-9-21(24)10-8-19)25-26-23(17)20-12-15-27(16-13-20)14-11-18-5-3-2-4-6-18/h2-10,20H,11-16H2,1H3,(H,25,26) GNGQVEIKYIVCPC-UHFFFAOYSA-N 50050474 4-[5-(4-Chloro-phenyl)-4-methyl-1H-pyrazol-3-yl]-1-phenethyl-piperidine::CHEMBL61079 D(2) dopamine receptor Homo sapiens 290 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10619737 103947644 CHEMBL61079 ZINC13755888 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099483 C(N1CCC(CC1)c1cc(Cc2ccccc2)[nH]n1)c1ccccc1 InChI=1S/C22H25N3/c1-3-7-18(8-4-1)15-21-16-22(24-23-21)20-11-13-25(14-12-20)17-19-9-5-2-6-10-19/h1-10,16,20H,11-15,17H2,(H,23,24) QAPWGFAFNBTWSU-UHFFFAOYSA-N 50059243 1-Benzyl-4-(5-benzyl-1H-pyrazol-3-yl)-piperidine::CHEMBL77148 D(2) dopamine receptor Homo sapiens 310 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10687967 103955087 CHEMBL77148 ZINC12356149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099485 Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(CC2CCCCC2)CC1 InChI=1S/C21H28ClN3/c22-19-8-6-17(7-9-19)20-14-21(24-23-20)18-10-12-25(13-11-18)15-16-4-2-1-3-5-16/h6-9,14,16,18H,1-5,10-13,15H2,(H,23,24) GTMVYXIUBGBXAW-UHFFFAOYSA-N 50059242 4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-cyclohexylmethyl-piperidine::CHEMBL420954 D(2) dopamine receptor Homo sapiens 120 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059242&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10760813 103955086 CHEMBL420954 ZINC13763818 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099486 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.4 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099487 Clc1ccc(CN2CCC(CC2)c2cc(no2)-c2ccc(Cl)cc2)cc1 InChI=1S/C21H20Cl2N2O/c22-18-5-1-15(2-6-18)14-25-11-9-17(10-12-25)21-13-20(24-26-21)16-3-7-19(23)8-4-16/h1-8,13,17H,9-12,14H2 BKCOTBJYDGSUFC-UHFFFAOYSA-N 50050475 1-(4-Chloro-benzyl)-4-[3-(4-chloro-phenyl)-isoxazol-5-yl]-piperidine::CHEMBL61195 D(2) dopamine receptor Homo sapiens 130 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691599 103947645 CHEMBL61195 ZINC13755890 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099489 Cc1c(nc(N)nc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C24H27ClN4/c1-17-22(19-7-9-21(25)10-8-19)27-24(26)28-23(17)20-12-15-29(16-13-20)14-11-18-5-3-2-4-6-18/h2-10,20H,11-16H2,1H3,(H2,26,27,28) LXBQQANESCMCJU-UHFFFAOYSA-N 50059240 4-(4-Chloro-phenyl)-5-methyl-6-(1-phenethyl-piperidin-4-yl)-pyrimidin-2-ylamine::CHEMBL80722 D(2) dopamine receptor Homo sapiens >1500 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10549355 103955084 CHEMBL80722 ZINC01540280 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099493 Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(Cc2cccc(Cl)c2)CC1 InChI=1S/C21H21Cl2N3/c22-18-6-4-16(5-7-18)20-13-21(25-24-20)17-8-10-26(11-9-17)14-15-2-1-3-19(23)12-15/h1-7,12-13,17H,8-11,14H2,(H,24,25) KYOJMOVGLXPOHH-UHFFFAOYSA-N 50059221 1-(3-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::CHEMBL78287 D(2) dopamine receptor Homo sapiens 570 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786367 103955065 CHEMBL78287 ZINC13763820 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099498 Cc1c(noc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C23H25ClN2O/c1-17-22(25-27-23(17)20-7-9-21(24)10-8-20)19-12-15-26(16-13-19)14-11-18-5-3-2-4-6-18/h2-10,19H,11-16H2,1H3 QDMAKDIDFJTXEL-UHFFFAOYSA-N 50050476 4-[5-(4-Chloro-phenyl)-4-methyl-isoxazol-3-yl]-1-phenethyl-piperidine::4-[5-(4-Chloro-phenyl)-4-methyl-isoxazol-3-yl]-1-phenethyl-piperidine (L-741742)::CHEMBL444309::L-741742 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133008 103947646 CHEMBL444309 3302 ZINC00602172 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099499 C(N1CCC(CC1)c1cc(n[nH]1)-c1ccccc1)c1ccccc1 InChI=1S/C21H23N3/c1-3-7-17(8-4-1)16-24-13-11-19(12-14-24)21-15-20(22-23-21)18-9-5-2-6-10-18/h1-10,15,19H,11-14,16H2,(H,22,23) CEFKCGBMUZVVLI-UHFFFAOYSA-N 50059227 1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine::CHEMBL25938 D(2) dopamine receptor Homo sapiens 66 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059227&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10615437 103955071 CHEMBL25938 ZINC13763829 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099501 C(Cc1ccccc1)N1CCC(CC1)c1cc(n[nH]1)-c1ccncc1 InChI=1S/C21H24N4/c1-2-4-17(5-3-1)8-13-25-14-9-19(10-15-25)21-16-20(23-24-21)18-6-11-22-12-7-18/h1-7,11-12,16,19H,8-10,13-15H2,(H,23,24) HXHXEJHGUJSCBJ-UHFFFAOYSA-N 50059234 4-[5-(1-Phenethyl-piperidin-4-yl)-2H-pyrazol-3-yl]-pyridine::CHEMBL79098 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059234&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10806501 103955078 CHEMBL79098 ZINC12356139 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50099510 Cc1c(onc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C23H25ClN2O/c1-17-22(19-7-9-21(24)10-8-19)25-27-23(17)20-12-15-26(16-13-20)14-11-18-5-3-2-4-6-18/h2-10,20H,11-16H2,1H3 CCWCGSVNRVVPNM-UHFFFAOYSA-N 50050471 4-[3-(4-Chloro-phenyl)-4-methyl-isoxazol-5-yl]-1-phenethyl-piperidine::CHEMBL293341 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm970111h 10.7270/Q2PN94R9 9240352 Rowley, M; Collins, I; Broughton, HB; Davey, WB; Baker, R; Emms, F; Marwood, R; Patel, S; Patel, S; Ragan, CI; Freedman, SB; Ball, R; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5029739 103947641 CHEMBL293341 ZINC02572468 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097264 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Homo sapiens 0.370000 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097265 FCCCc1cccc(c1)C(=O)NC[C@@H]1CCCN1CC=C InChI=1S/C18H25FN2O/c1-2-11-21-12-5-9-17(21)14-20-18(22)16-8-3-6-15(13-16)7-4-10-19/h2-3,6,8,13,17H,1,4-5,7,9-12,14H2,(H,20,22)/t17-/m0/s1 PFVOHXHHGRINAB-KRWDZBQOSA-N 50015491 CHEMBL3265329 D(2) dopamine receptor Homo sapiens 0.630000 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656834 242058649 CHEMBL3265329 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097266 Ic1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C16H22INO/c17-15-3-5-16(6-4-15)19-12-14-7-9-18(10-8-14)11-13-1-2-13/h3-6,13-14H,1-2,7-12H2 JXQVMKWSWFFOHD-UHFFFAOYSA-N 50058007 1-Cyclopropylmethyl-4-(4-iodo-phenoxymethyl)-piperidine::CHEMBL44739 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058007&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290508 103953986 CHEMBL44739 ZINC13605804 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097267 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.850000 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097268 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Homo sapiens 1.2 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097271 Brc1cccc(OCC2CCN(CC3CC3)CC2)c1 InChI=1S/C16H22BrNO/c17-15-2-1-3-16(10-15)19-12-14-6-8-18(9-7-14)11-13-4-5-13/h1-3,10,13-14H,4-9,11-12H2 XTOXUNBIAXSPCM-UHFFFAOYSA-N 50058011 4-(3-Bromo-phenoxymethyl)-1-cyclopropylmethyl-piperidine::CHEMBL289196 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058011&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290522 103953990 CHEMBL289196 ZINC13605814 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097273 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Homo sapiens 6.1 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097275 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N3CCC[C@H]3C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCC(N)=O)C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C100H172N38O22S/c1-4-47-135-48-18-23-59(135)56-124-81(144)60-53-58(54-73(159-2)80(60)160-3)22-21-52-161-74-55-79(143)138(93(74)156)49-11-5-6-34-77(141)123-57-78(142)125-61(26-12-41-117-95(105)106)82(145)126-62(24-7-9-39-101)83(146)127-63(25-8-10-40-102)84(147)128-64(27-13-42-118-96(107)108)85(148)129-66(29-15-44-120-98(111)112)87(150)132-68(35-37-75(103)139)89(152)131-65(28-14-43-119-97(109)110)86(149)130-67(30-16-45-121-99(113)114)88(151)133-69(31-17-46-122-100(115)116)91(154)137-51-20-33-72(137)92(155)136-50-19-32-71(136)90(153)134-70(94(157)158)36-38-76(104)140/h4,53-54,59,61-72,74H,1,5-52,55-57,101-102H2,2-3H3,(H2,103,139)(H2,104,140)(H,123,141)(H,124,144)(H,125,142)(H,126,145)(H,127,146)(H,128,147)(H,129,148)(H,130,149)(H,131,152)(H,132,150)(H,133,151)(H,134,153)(H,157,158)(H4,105,106,117)(H4,107,108,118)(H4,109,110,119)(H4,111,112,120)(H4,113,114,121)(H4,115,116,122)/t59-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,74?/m0/s1 JTBUMIDWZWHPHA-NQWOSTQESA-N 50015492 CHEMBL3265038 D(2) dopamine receptor Homo sapiens 21 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656835 242058650 CHEMBL3265038 C02716 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097276 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C83H147N33O17S/c1-4-41-115-42-18-21-50(115)48-105-67(120)51-45-49(46-61(132-2)66(51)133-3)20-19-44-134-62-47-65(119)116(76(62)129)43-11-5-6-30-64(118)106-52(24-12-35-99-78(87)88)68(121)107-53(22-7-9-33-84)69(122)108-54(23-8-10-34-85)70(123)109-55(25-13-36-100-79(89)90)71(124)110-57(27-15-38-102-81(93)94)73(126)113-59(31-32-63(86)117)75(128)112-56(26-14-37-101-80(91)92)72(125)111-58(28-16-39-103-82(95)96)74(127)114-60(77(130)131)29-17-40-104-83(97)98/h4,45-46,50,52-60,62H,1,5-44,47-48,84-85H2,2-3H3,(H2,86,117)(H,105,120)(H,106,118)(H,107,121)(H,108,122)(H,109,123)(H,110,124)(H,111,125)(H,112,128)(H,113,126)(H,114,127)(H,130,131)(H4,87,88,99)(H4,89,90,100)(H4,91,92,101)(H4,93,94,102)(H4,95,96,103)(H4,97,98,104)/t50-,52-,53-,54-,55-,56-,57-,58-,59-,60-,62?/m0/s1 UYYFSAYTJHQCKJ-SNJMGREUSA-N 50015493 CHEMBL3265039 D(2) dopamine receptor Homo sapiens 9.7 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656836 242058651 CHEMBL3265039 C04026 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097279 I\C=C\CN1CCC(COc2ccc(cc2)C#N)CC1 InChI=1S/C16H19IN2O/c17-8-1-9-19-10-6-15(7-11-19)13-20-16-4-2-14(12-18)3-5-16/h1-5,8,15H,6-7,9-11,13H2/b8-1+ QJRRQEZUOGOHQN-UNXLUWIOSA-N 50058020 4-[1-((E)-3-Iodo-allyl)-piperidin-4-ylmethoxy]-benzonitrile::CHEMBL2347004::CHEMBL274585 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9864749 103953999 CHEMBL274585CHEMBL2347004 ZINC06535253 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097281 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C71H101N17O15S/c1-7-26-86-27-13-17-48(86)39-77-63(93)50-31-45(33-56(102-5)61(50)103-6)16-15-30-104-57-36-59(91)88(69(57)99)28-11-9-10-20-58(90)81-52(34-46-37-74-40-78-46)65(95)80-43(4)62(92)85-60(42(3)8-2)67(97)83-53(32-44-21-23-49(89)24-22-44)68(98)87-29-14-19-55(87)66(96)82-51(18-12-25-76-71(72)73)64(94)84-54(70(100)101)35-47-38-75-41-79-47/h7,21-24,31,33,37-38,40-43,48,51-55,57,60,89H,1,8-20,25-30,32,34-36,39H2,2-6H3,(H,74,78)(H,75,79)(H,77,93)(H,80,95)(H,81,90)(H,82,96)(H,83,97)(H,84,94)(H,85,92)(H,100,101)(H4,72,73,76)/t42-,43-,48-,51-,52-,53-,54-,55-,57?,60-/m0/s1 NAZPPIPSJUCMAI-GGQJSIIWSA-N 50015494 CHEMBL3265040 D(2) dopamine receptor Homo sapiens 10 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015494&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656837 242058652 CHEMBL3265040 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097284 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N3CCC[C@H]3C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CO)C(=O)N3CCC[C@H]3C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N3CCC[C@H]3C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C101H140N22O21S2/c1-8-37-118-38-17-24-64(118)55-108-87(128)67-46-60(47-80(143-5)86(67)144-6)23-22-44-146-81-51-83(127)123(99(81)140)39-15-9-10-34-82(126)116-85(59(4)125)94(135)113-73(50-63-54-104-57-109-63)90(131)111-71(29-16-36-105-101(102)103)95(136)121-42-20-32-78(121)98(139)120-41-19-30-76(120)91(132)110-70(35-45-145-7)88(129)112-72(48-61-52-106-68-27-13-11-25-65(61)68)89(130)115-75(56-124)97(138)119-40-18-31-77(119)92(133)117-84(58(2)3)93(134)114-74(96(137)122-43-21-33-79(122)100(141)142)49-62-53-107-69-28-14-12-26-66(62)69/h8,11-14,25-28,46-47,52-54,57-59,64,70-79,81,84-85,106-107,124-125H,1,9-10,15-24,29-45,48-51,55-56H2,2-7H3,(H,104,109)(H,108,128)(H,110,132)(H,111,131)(H,112,129)(H,113,135)(H,114,134)(H,115,130)(H,116,126)(H,117,133)(H,141,142)(H4,102,103,105)/t59-,64+,70+,71+,72+,73+,74+,75+,76+,77+,78+,79+,81?,84+,85+/m1/s1 IXSUYJGJHMRPNB-LZPMYQHXSA-N 50015495 CHEMBL3265041 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656838 242058653 CHEMBL3265041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097285 CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)=O InChI=1S/C164H265N35O41S/c1-28-63-198-64-44-47-105(198)82-171-144(217)108-74-103(76-126(239-26)138(108)240-27)46-45-66-241-127-80-132(207)199(163(127)236)65-43-31-32-54-128(203)170-83-129(204)181-121(77-104-81-169-109-49-34-33-48-107(104)109)158(231)197-137(101(25)201)162(235)191-119(72-92(14)15)154(227)190-122(78-133(208)209)157(230)194-125(86-200)159(232)175-96(20)139(212)172-84-131(206)180-120(75-102-55-57-106(202)58-56-102)155(228)188-118(71-91(12)13)153(226)187-114(67-87(4)5)145(218)173-85-130(205)179-110(50-35-39-59-165)148(221)195-135(94(18)29-2)160(233)192-123(79-134(210)211)156(229)189-117(70-90(10)11)152(225)184-111(51-36-40-60-166)146(219)176-100(24)143(216)186-115(68-88(6)7)150(223)177-97(21)140(213)174-98(22)142(215)185-116(69-89(8)9)151(224)178-99(23)141(214)182-112(52-37-41-61-167)147(220)183-113(53-38-42-62-168)149(222)196-136(95(19)30-3)161(234)193-124(164(237)238)73-93(16)17/h28,33-34,48-49,55-58,74,76,81,87-101,105,110-125,127,135-137,169,200-202H,1,29-32,35-47,50-54,59-73,75,77-80,82-86,165-168H2,2-27H3,(H,170,203)(H,171,217)(H,172,212)(H,173,218)(H,174,213)(H,175,232)(H,176,219)(H,177,223)(H,178,224)(H,179,205)(H,180,206)(H,181,204)(H,182,214)(H,183,220)(H,184,225)(H,185,215)(H,186,216)(H,187,226)(H,188,228)(H,189,229)(H,190,227)(H,191,235)(H,192,233)(H,193,234)(H,194,230)(H,195,221)(H,196,222)(H,197,231)(H,208,209)(H,210,211)(H,237,238)/t94-,95-,96-,97-,98-,99-,100-,101+,105-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,127?,135-,136-,137-/m0/s1 RFSDKFBYYCHXSF-QXXDMJPLSA-N 50015496 CHEMBL3265042 D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015496&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656839 242058654 CHEMBL3265042 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097288 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C134H209N37O26S2/c1-9-63-170-64-33-38-84(170)77-153-114(177)87-68-81(70-104(196-6)113(87)197-7)37-34-66-199-105-74-110(176)171(130(105)193)65-29-13-16-50-109(175)154-90(47-30-60-148-132(142)143)115(178)159-97(52-54-107(140)173)123(186)169-111(78(4)10-2)128(191)162-93(45-23-27-58-137)122(185)168-112(79(5)11-3)129(192)167-102(72-83-76-152-89-42-20-18-40-86(83)89)126(189)164-100(69-80-35-14-12-15-36-80)124(187)160-96(51-53-106(139)172)120(183)166-103(73-108(141)174)127(190)158-95(49-32-62-150-134(146)147)116(179)156-94(48-31-61-149-133(144)145)117(180)161-98(55-67-198-8)121(184)155-92(44-22-26-57-136)119(182)165-101(71-82-75-151-88-41-19-17-39-85(82)88)125(188)157-91(43-21-25-56-135)118(181)163-99(131(194)195)46-24-28-59-138/h9,12,14-15,17-20,35-36,39-42,68,70,75-76,78-79,84,90-103,105,111-112,151-152H,1,10-11,13,16,21-34,37-38,43-67,69,71-74,77,135-138H2,2-8H3,(H2,139,172)(H2,140,173)(H2,141,174)(H,153,177)(H,154,175)(H,155,184)(H,156,179)(H,157,188)(H,158,190)(H,159,178)(H,160,187)(H,161,180)(H,162,191)(H,163,181)(H,164,189)(H,165,182)(H,166,183)(H,167,192)(H,168,185)(H,169,186)(H,194,195)(H4,142,143,148)(H4,144,145,149)(H4,146,147,150)/t78-,79-,84-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,105?,111-,112-/m0/s1 RWNKNDBSFFMYLR-FFAHUNIMSA-N 50015497 CHEMBL3265043 D(2) dopamine receptor Homo sapiens 8.1 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656840 242058655 CHEMBL3265043 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097291 FCCCN1CCC(COc2ccc(Br)cc2)CC1 InChI=1S/C15H21BrFNO/c16-14-2-4-15(5-3-14)19-12-13-6-10-18(11-7-13)9-1-8-17/h2-5,13H,1,6-12H2 AHAGIIZNUZGGLS-UHFFFAOYSA-N 50058023 4-(4-Bromo-phenoxymethyl)-1-(3-fluoro-propyl)-piperidine::CHEMBL45156 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm960720+ 10.7270/Q29G5KX8 9171875 Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC ANSTO http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058023&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10568394 103954002 CHEMBL45156 ZINC13605810 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097294 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N3CCC[C@H]3C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C85H143N23O19S2/c1-9-39-106-40-19-23-53(106)49-96-72(113)54-46-52(47-64(126-6)71(54)127-7)22-21-43-129-65-48-69(112)108(82(65)123)41-16-10-11-29-68(111)105-70(51(4)5)80(121)102-60(31-33-67(89)110)78(119)100-57(26-17-37-94-84(90)91)74(115)97-55(24-12-14-35-86)73(114)99-58(27-18-38-95-85(92)93)75(116)101-59(30-32-66(88)109)77(118)98-56(25-13-15-36-87)76(117)104-62(45-50(2)3)79(120)103-61(34-44-128-8)81(122)107-42-20-28-63(107)83(124)125/h9,46-47,50-51,53,55-63,65,70H,1,10-45,48-49,86-87H2,2-8H3,(H2,88,109)(H2,89,110)(H,96,113)(H,97,115)(H,98,118)(H,99,114)(H,100,119)(H,101,116)(H,102,121)(H,103,120)(H,104,117)(H,105,111)(H,124,125)(H4,90,91,94)(H4,92,93,95)/t53-,55-,56-,57-,58-,59-,60-,61-,62-,63-,65?,70-/m0/s1 LWJRZMFKJXXHGW-YOTKAZDMSA-N 50015498 CHEMBL3265044 D(2) dopamine receptor Homo sapiens 13 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656841 242058656 CHEMBL3265044 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097295 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C150H216N36O44S/c1-6-56-185-57-25-34-95(185)78-162-131(210)98-68-94(74-113(229-4)130(98)230-5)33-26-67-231-114-77-122(199)186(147(114)226)58-22-10-17-39-117(194)179-128(87(2)188)145(224)177-108(71-91-31-15-9-16-32-91)141(220)173-107(70-90-29-13-8-14-30-90)140(219)172-105(72-92-40-44-96(190)45-41-92)133(212)163-79-118(195)161-80-119(196)166-112(86-187)144(223)167-99(37-23-54-159-149(154)155)132(211)164-81-120(197)165-100(36-19-21-53-158-121(198)82-181-59-61-182(83-125(204)205)63-65-184(85-127(208)209)66-64-183(62-60-181)84-126(206)207)134(213)168-102(38-24-55-160-150(156)157)135(214)175-109(75-115(152)192)143(222)176-110(76-116(153)193)142(221)174-106(69-89-27-11-7-12-28-89)139(218)169-101(35-18-20-52-151)138(217)180-129(88(3)189)146(225)171-104(49-51-124(202)203)136(215)170-103(48-50-123(200)201)137(216)178-111(148(227)228)73-93-42-46-97(191)47-43-93/h6-9,11-16,27-32,40-47,68,74,87-88,95,99-112,114,128-129,187-191H,1,10,17-26,33-39,48-67,69-73,75-86,151H2,2-5H3,(H2,152,192)(H2,153,193)(H,158,198)(H,161,195)(H,162,210)(H,163,212)(H,164,211)(H,165,197)(H,166,196)(H,167,223)(H,168,213)(H,169,218)(H,170,215)(H,171,225)(H,172,219)(H,173,220)(H,174,221)(H,175,214)(H,176,222)(H,177,224)(H,178,216)(H,179,194)(H,180,217)(H,200,201)(H,202,203)(H,204,205)(H,206,207)(H,208,209)(H,227,228)(H4,154,155,159)(H4,156,157,160)/t87-,88-,95+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112+,114?,128+,129+/m1/s1 PHKMWKWTHXWZLN-GENNJICVSA-N 50015499 CHEMBL3265045 D(2) dopamine receptor Homo sapiens 8.0 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656842 242058657 CHEMBL3265045 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097296 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C75H108N18O16S/c1-7-29-91-30-14-18-51(91)42-82-67(99)53-34-48(36-59(108-5)65(53)109-6)17-16-33-110-60-39-63(97)93(73(60)105)31-11-9-10-21-61(95)80-27-13-22-62(96)86-55(37-49-40-78-43-83-49)69(101)85-46(4)66(98)90-64(45(3)8-2)71(103)88-56(35-47-23-25-52(94)26-24-47)72(104)92-32-15-20-58(92)70(102)87-54(19-12-28-81-75(76)77)68(100)89-57(74(106)107)38-50-41-79-44-84-50/h7,23-26,34,36,40-41,43-46,51,54-58,60,64,94H,1,8-22,27-33,35,37-39,42H2,2-6H3,(H,78,83)(H,79,84)(H,80,95)(H,82,99)(H,85,101)(H,86,96)(H,87,102)(H,88,103)(H,89,100)(H,90,98)(H,106,107)(H4,76,77,81)/t45-,46-,51-,54-,55-,56-,57-,58-,60?,64-/m0/s1 PWTRAIAVXRQYHQ-QDNSEPHBSA-N 50015500 CHEMBL3265046 D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656843 242058658 CHEMBL3265046 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097297 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)COCCOCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C77H112N18O18S/c1-7-27-93-28-13-17-53(93)43-84-69(101)55-35-50(37-61(110-5)67(55)111-6)16-15-34-114-62-40-65(99)95(75(62)107)29-11-9-10-20-63(97)82-26-31-112-32-33-113-44-64(98)88-57(38-51-41-80-45-85-51)71(103)87-48(4)68(100)92-66(47(3)8-2)73(105)90-58(36-49-21-23-54(96)24-22-49)74(106)94-30-14-19-60(94)72(104)89-56(18-12-25-83-77(78)79)70(102)91-59(76(108)109)39-52-42-81-46-86-52/h7,21-24,35,37,41-42,45-48,53,56-60,62,66,96H,1,8-20,25-34,36,38-40,43-44H2,2-6H3,(H,80,85)(H,81,86)(H,82,97)(H,84,101)(H,87,103)(H,88,98)(H,89,104)(H,90,105)(H,91,102)(H,92,100)(H,108,109)(H4,78,79,83)/t47-,48-,53-,56-,57-,58-,59-,60-,62?,66-/m0/s1 HZFJQBUUXZYDBD-LGIDIJRNSA-N 50015501 CHEMBL3265047 D(2) dopamine receptor Homo sapiens 30 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656844 242058659 CHEMBL3265047 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097298 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCOCCOCCOCCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C81H120N18O19S/c1-7-29-97-30-13-18-57(97)48-88-73(105)59-40-54(42-65(114-5)71(59)115-6)17-15-39-119-66-45-69(103)99(79(66)111)31-11-9-10-21-67(101)86-28-16-33-116-35-37-118-38-36-117-34-26-68(102)92-61(43-55-46-84-49-89-55)75(107)91-52(4)72(104)96-70(51(3)8-2)77(109)94-62(41-53-22-24-58(100)25-23-53)78(110)98-32-14-20-64(98)76(108)93-60(19-12-27-87-81(82)83)74(106)95-63(80(112)113)44-56-47-85-50-90-56/h7,22-25,40,42,46-47,49-52,57,60-64,66,70,100H,1,8-21,26-39,41,43-45,48H2,2-6H3,(H,84,89)(H,85,90)(H,86,101)(H,88,105)(H,91,107)(H,92,102)(H,93,108)(H,94,109)(H,95,106)(H,96,104)(H,112,113)(H4,82,83,87)/t51-,52-,57-,60-,61-,62-,63-,64-,66?,70-/m0/s1 LKASSMVPOODRNL-PBFRATGOSA-N 50015502 CHEMBL3265048 D(2) dopamine receptor Homo sapiens 24 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656845 242058660 CHEMBL3265048 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097299 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C82H122N18O20S/c1-7-28-98-29-13-17-58(98)49-89-74(106)60-41-55(43-66(115-5)72(60)116-6)16-15-40-121-67-46-70(104)100(80(67)112)30-11-9-10-20-68(102)87-27-33-118-35-37-120-39-38-119-36-34-117-32-25-69(103)93-62(44-56-47-85-50-90-56)76(108)92-53(4)73(105)97-71(52(3)8-2)78(110)95-63(42-54-21-23-59(101)24-22-54)79(111)99-31-14-19-65(99)77(109)94-61(18-12-26-88-82(83)84)75(107)96-64(81(113)114)45-57-48-86-51-91-57/h7,21-24,41,43,47-48,50-53,58,61-65,67,71,101H,1,8-20,25-40,42,44-46,49H2,2-6H3,(H,85,90)(H,86,91)(H,87,102)(H,89,106)(H,92,108)(H,93,103)(H,94,109)(H,95,110)(H,96,107)(H,97,105)(H,113,114)(H4,83,84,88)/t52-,53-,58-,61-,62-,63-,64-,65-,67?,71-/m0/s1 LPWQYVIMWOVNJE-BAXQJZDKSA-N 50015511 CHEMBL3265049 D(2) dopamine receptor Homo sapiens 1.5 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656846 103927264 CHEMBL3265049 ZINC29480929 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097300 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C86H130N18O22S/c1-7-28-102-29-13-17-62(102)53-93-78(110)64-45-59(47-70(119-5)76(64)120-6)16-15-44-127-71-50-74(108)104(84(71)116)30-11-9-10-20-72(106)91-27-33-122-35-37-124-39-41-126-43-42-125-40-38-123-36-34-121-32-25-73(107)97-66(48-60-51-89-54-94-60)80(112)96-57(4)77(109)101-75(56(3)8-2)82(114)99-67(46-58-21-23-63(105)24-22-58)83(115)103-31-14-19-69(103)81(113)98-65(18-12-26-92-86(87)88)79(111)100-68(85(117)118)49-61-52-90-55-95-61/h7,21-24,45,47,51-52,54-57,62,65-69,71,75,105H,1,8-20,25-44,46,48-50,53H2,2-6H3,(H,89,94)(H,90,95)(H,91,106)(H,93,110)(H,96,112)(H,97,107)(H,98,113)(H,99,114)(H,100,111)(H,101,109)(H,117,118)(H4,87,88,92)/t56-,57-,62-,65-,66-,67-,68-,69-,71?,75-/m0/s1 ZDFULMHHALUTIK-XDBKOMMSSA-N 50015512 CHEMBL3265314 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656847 103927265 CHEMBL3265314 ZINC29478046 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097301 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C90H138N18O24S/c1-7-28-106-29-13-17-66(106)57-97-82(114)68-49-63(51-74(123-5)80(68)124-6)16-15-48-133-75-54-78(112)108(88(75)120)30-11-9-10-20-76(110)95-27-33-126-35-37-128-39-41-130-43-45-132-47-46-131-44-42-129-40-38-127-36-34-125-32-25-77(111)101-70(52-64-55-93-58-98-64)84(116)100-61(4)81(113)105-79(60(3)8-2)86(118)103-71(50-62-21-23-67(109)24-22-62)87(119)107-31-14-19-73(107)85(117)102-69(18-12-26-96-90(91)92)83(115)104-72(89(121)122)53-65-56-94-59-99-65/h7,21-24,49,51,55-56,58-61,66,69-73,75,79,109H,1,8-20,25-48,50,52-54,57H2,2-6H3,(H,93,98)(H,94,99)(H,95,110)(H,97,114)(H,100,116)(H,101,111)(H,102,117)(H,103,118)(H,104,115)(H,105,113)(H,121,122)(H4,91,92,96)/t60-,61-,66-,69-,70-,71-,72-,73-,75?,79-/m0/s1 FSYXFKAGLZZMPT-BURBDGKISA-N 50015513 CHEMBL3265315 D(2) dopamine receptor Homo sapiens 54 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656848 103927266 CHEMBL3265315 ZINC29478908 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097302 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C98H154N18O28S/c1-7-28-114-29-13-17-74(114)65-105-90(122)76-57-71(59-82(131-5)88(76)132-6)16-15-56-145-83-62-86(120)116(96(83)128)30-11-9-10-20-84(118)103-27-33-134-35-37-136-39-41-138-43-45-140-47-49-142-51-53-144-55-54-143-52-50-141-48-46-139-44-42-137-40-38-135-36-34-133-32-25-85(119)109-78(60-72-63-101-66-106-72)92(124)108-69(4)89(121)113-87(68(3)8-2)94(126)111-79(58-70-21-23-75(117)24-22-70)95(127)115-31-14-19-81(115)93(125)110-77(18-12-26-104-98(99)100)91(123)112-80(97(129)130)61-73-64-102-67-107-73/h7,21-24,57,59,63-64,66-69,74,77-81,83,87,117H,1,8-20,25-56,58,60-62,65H2,2-6H3,(H,101,106)(H,102,107)(H,103,118)(H,105,122)(H,108,124)(H,109,119)(H,110,125)(H,111,126)(H,112,123)(H,113,121)(H,129,130)(H4,99,100,104)/t68-,69-,74-,77-,78-,79-,80-,81-,83?,87-/m0/s1 RQXZLQIADGREAL-YSEBVQFVSA-N 50015514 CHEMBL3265316 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656849 103927267 CHEMBL3265316 ZINC29469503 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097303 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)NCCOCCOCCOCCOCCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C161H237N37O49S/c1-6-58-197-59-25-34-105(197)88-174-142(223)108-78-104(84-123(242-4)141(108)243-5)33-26-77-248-124-87-133(212)198(158(124)239)60-22-10-17-39-127(206)170-57-70-245-72-74-247-76-75-246-73-71-244-69-52-128(207)191-139(97(2)200)156(237)189-118(81-101-31-15-9-16-32-101)152(233)185-117(80-100-29-13-8-14-30-100)151(232)184-115(82-102-40-44-106(202)45-41-102)144(225)175-89-129(208)173-90-130(209)178-122(96-199)155(236)179-109(37-23-55-171-160(165)166)143(224)176-91-131(210)177-110(36-19-21-54-169-132(211)92-193-61-63-194(93-136(217)218)65-67-196(95-138(221)222)68-66-195(64-62-193)94-137(219)220)145(226)180-112(38-24-56-172-161(167)168)146(227)187-119(85-125(163)204)154(235)188-120(86-126(164)205)153(234)186-116(79-99-27-11-7-12-28-99)150(231)181-111(35-18-20-53-162)149(230)192-140(98(3)201)157(238)183-114(49-51-135(215)216)147(228)182-113(48-50-134(213)214)148(229)190-121(159(240)241)83-103-42-46-107(203)47-43-103/h6-9,11-16,27-32,40-47,78,84,97-98,105,109-122,124,139-140,199-203H,1,10,17-26,33-39,48-77,79-83,85-96,162H2,2-5H3,(H2,163,204)(H2,164,205)(H,169,211)(H,170,206)(H,173,208)(H,174,223)(H,175,225)(H,176,224)(H,177,210)(H,178,209)(H,179,236)(H,180,226)(H,181,231)(H,182,228)(H,183,238)(H,184,232)(H,185,233)(H,186,234)(H,187,227)(H,188,235)(H,189,237)(H,190,229)(H,191,207)(H,192,230)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H,240,241)(H4,165,166,171)(H4,167,168,172)/t97-,98-,105+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,124?,139+,140+/m1/s1 XLHUMARZTHVCFQ-GTMXNFSCSA-N 50015515 CHEMBL3265317 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656850 103927268 CHEMBL3265317 ZINC29472356 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097304 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C165H245N37O51S/c1-6-58-201-59-25-34-109(201)92-178-146(227)112-82-108(88-127(246-4)145(112)247-5)33-26-81-254-128-91-137(216)202(162(128)243)60-22-10-17-39-131(210)174-57-70-249-72-74-251-76-78-253-80-79-252-77-75-250-73-71-248-69-52-132(211)195-143(101(2)204)160(241)193-122(85-105-31-15-9-16-32-105)156(237)189-121(84-104-29-13-8-14-30-104)155(236)188-119(86-106-40-44-110(206)45-41-106)148(229)179-93-133(212)177-94-134(213)182-126(100-203)159(240)183-113(37-23-55-175-164(169)170)147(228)180-95-135(214)181-114(36-19-21-54-173-136(215)96-197-61-63-198(97-140(221)222)65-67-200(99-142(225)226)68-66-199(64-62-197)98-141(223)224)149(230)184-116(38-24-56-176-165(171)172)150(231)191-123(89-129(167)208)158(239)192-124(90-130(168)209)157(238)190-120(83-103-27-11-7-12-28-103)154(235)185-115(35-18-20-53-166)153(234)196-144(102(3)205)161(242)187-118(49-51-139(219)220)151(232)186-117(48-50-138(217)218)152(233)194-125(163(244)245)87-107-42-46-111(207)47-43-107/h6-9,11-16,27-32,40-47,82,88,101-102,109,113-126,128,143-144,203-207H,1,10,17-26,33-39,48-81,83-87,89-100,166H2,2-5H3,(H2,167,208)(H2,168,209)(H,173,215)(H,174,210)(H,177,212)(H,178,227)(H,179,229)(H,180,228)(H,181,214)(H,182,213)(H,183,240)(H,184,230)(H,185,235)(H,186,232)(H,187,242)(H,188,236)(H,189,237)(H,190,238)(H,191,231)(H,192,239)(H,193,241)(H,194,233)(H,195,211)(H,196,234)(H,217,218)(H,219,220)(H,221,222)(H,223,224)(H,225,226)(H,244,245)(H4,169,170,175)(H4,171,172,176)/t101-,102-,109+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,123+,124+,125+,126+,128?,143+,144+/m1/s1 YWHIUWBZLAIORJ-KJSDXJSGSA-N 50015518 CHEMBL3265318 D(2) dopamine receptor Homo sapiens 36 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656851 103927271 CHEMBL3265318 ZINC29475395 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097305 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C169H253N37O53S/c1-6-58-205-59-25-34-113(205)96-182-150(231)116-86-112(92-131(250-4)149(116)251-5)33-26-85-260-132-95-141(220)206(166(132)247)60-22-10-17-39-135(214)178-57-70-253-72-74-255-76-78-257-80-82-259-84-83-258-81-79-256-77-75-254-73-71-252-69-52-136(215)199-147(105(2)208)164(245)197-126(89-109-31-15-9-16-32-109)160(241)193-125(88-108-29-13-8-14-30-108)159(240)192-123(90-110-40-44-114(210)45-41-110)152(233)183-97-137(216)181-98-138(217)186-130(104-207)163(244)187-117(37-23-55-179-168(173)174)151(232)184-99-139(218)185-118(36-19-21-54-177-140(219)100-201-61-63-202(101-144(225)226)65-67-204(103-146(229)230)68-66-203(64-62-201)102-145(227)228)153(234)188-120(38-24-56-180-169(175)176)154(235)195-127(93-133(171)212)162(243)196-128(94-134(172)213)161(242)194-124(87-107-27-11-7-12-28-107)158(239)189-119(35-18-20-53-170)157(238)200-148(106(3)209)165(246)191-122(49-51-143(223)224)155(236)190-121(48-50-142(221)222)156(237)198-129(167(248)249)91-111-42-46-115(211)47-43-111/h6-9,11-16,27-32,40-47,86,92,105-106,113,117-130,132,147-148,207-211H,1,10,17-26,33-39,48-85,87-91,93-104,170H2,2-5H3,(H2,171,212)(H2,172,213)(H,177,219)(H,178,214)(H,181,216)(H,182,231)(H,183,233)(H,184,232)(H,185,218)(H,186,217)(H,187,244)(H,188,234)(H,189,239)(H,190,236)(H,191,246)(H,192,240)(H,193,241)(H,194,242)(H,195,235)(H,196,243)(H,197,245)(H,198,237)(H,199,215)(H,200,238)(H,221,222)(H,223,224)(H,225,226)(H,227,228)(H,229,230)(H,248,249)(H4,173,174,179)(H4,175,176,180)/t105-,106-,113+,117+,118+,119+,120+,121+,122+,123+,124+,125+,126+,127+,128+,129+,130+,132?,147+,148+/m1/s1 PXQSZLIMMPVGFB-QTRRZBIWSA-N 50015524 CHEMBL3265319 D(2) dopamine receptor Homo sapiens 43 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015524&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656852 103927277 CHEMBL3265319 ZINC29478518 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097306 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C173H261N37O55S/c1-6-58-209-59-25-34-117(209)100-186-154(235)120-90-116(96-135(254-4)153(120)255-5)33-26-89-266-136-99-145(224)210(170(136)251)60-22-10-17-39-139(218)182-57-70-257-72-74-259-76-78-261-80-82-263-84-86-265-88-87-264-85-83-262-81-79-260-77-75-258-73-71-256-69-52-140(219)203-151(109(2)212)168(249)201-130(93-113-31-15-9-16-32-113)164(245)197-129(92-112-29-13-8-14-30-112)163(244)196-127(94-114-40-44-118(214)45-41-114)156(237)187-101-141(220)185-102-142(221)190-134(108-211)167(248)191-121(37-23-55-183-172(177)178)155(236)188-103-143(222)189-122(36-19-21-54-181-144(223)104-205-61-63-206(105-148(229)230)65-67-208(107-150(233)234)68-66-207(64-62-205)106-149(231)232)157(238)192-124(38-24-56-184-173(179)180)158(239)199-131(97-137(175)216)166(247)200-132(98-138(176)217)165(246)198-128(91-111-27-11-7-12-28-111)162(243)193-123(35-18-20-53-174)161(242)204-152(110(3)213)169(250)195-126(49-51-147(227)228)159(240)194-125(48-50-146(225)226)160(241)202-133(171(252)253)95-115-42-46-119(215)47-43-115/h6-9,11-16,27-32,40-47,90,96,109-110,117,121-134,136,151-152,211-215H,1,10,17-26,33-39,48-89,91-95,97-108,174H2,2-5H3,(H2,175,216)(H2,176,217)(H,181,223)(H,182,218)(H,185,220)(H,186,235)(H,187,237)(H,188,236)(H,189,222)(H,190,221)(H,191,248)(H,192,238)(H,193,243)(H,194,240)(H,195,250)(H,196,244)(H,197,245)(H,198,246)(H,199,239)(H,200,247)(H,201,249)(H,202,241)(H,203,219)(H,204,242)(H,225,226)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,252,253)(H4,177,178,183)(H4,179,180,184)/t109-,110-,117+,121+,122+,123+,124+,125+,126+,127+,128+,129+,130+,131+,132+,133+,134+,136?,151+,152+/m1/s1 HVEBDZMABXCCBQ-YORAJNPUSA-N 50015526 CHEMBL3265320 D(2) dopamine receptor Homo sapiens 45 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656853 103927279 CHEMBL3265320 ZINC29478055 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097307 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCNC(=O)O\N=C\c1ccc(cc1)[Si](F)(C(C)(C)C)C(C)(C)C)NC(=O)CCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C104H156FN21O23SSi/c1-13-42-124-43-21-25-74(124)64-113-92(132)77-55-71(57-84(143-11)90(77)144-12)24-23-54-150-85-60-88(130)126(99(85)139)44-19-15-16-29-86(128)110-41-47-146-49-51-148-53-52-147-50-48-145-46-38-87(129)118-78(26-17-18-39-112-102(142)149-116-61-70-32-36-76(37-33-70)151(105,103(5,6)7)104(8,9)10)93(133)120-80(58-72-62-108-65-114-72)95(135)117-68(4)91(131)123-89(67(3)14-2)97(137)121-81(56-69-30-34-75(127)35-31-69)98(138)125-45-22-28-83(125)96(136)119-79(27-20-40-111-101(106)107)94(134)122-82(100(140)141)59-73-63-109-66-115-73/h13,30-37,55,57,61-63,65-68,74,78-83,85,89,127H,1,14-29,38-54,56,58-60,64H2,2-12H3,(H,108,114)(H,109,115)(H,110,128)(H,112,142)(H,113,132)(H,117,135)(H,118,129)(H,119,136)(H,120,133)(H,121,137)(H,122,134)(H,123,131)(H,140,141)(H4,106,107,111)/b116-61+/t67-,68-,74-,78-,79-,80-,81-,82-,83-,85?,89-/m0/s1 YMYUWKBPKXTFOI-WDNSJAFCSA-N 50015527 CHEMBL3265321 D(2) dopamine receptor Homo sapiens 6.0 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656854 103927280 CHEMBL3265321 ZINC29479916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097308 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)NC(=O)CCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)CC(SCCCc2cc(OC)c(OC)c(c2)C(=O)NC[C@@H]2CCCN2CC=C)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C104H160N24O28S/c1-7-32-126-33-15-19-74(126)61-112-95(141)76-53-71(55-83(151-5)93(76)152-6)18-17-52-157-84-58-88(133)128(102(84)148)34-13-9-10-23-85(130)110-31-45-154-47-49-156-51-50-155-48-46-153-44-28-86(131)116-77(20-11-12-29-109-87(132)62-122-36-38-123(63-89(134)135)40-42-125(65-91(138)139)43-41-124(39-37-122)64-90(136)137)96(142)118-79(56-72-59-107-66-113-72)98(144)115-69(4)94(140)121-92(68(3)8-2)100(146)119-80(54-70-24-26-75(129)27-25-70)101(147)127-35-16-22-82(127)99(145)117-78(21-14-30-111-104(105)106)97(143)120-81(103(149)150)57-73-60-108-67-114-73/h7,24-27,53,55,59-60,66-69,74,77-82,84,92,129H,1,8-23,28-52,54,56-58,61-65H2,2-6H3,(H,107,113)(H,108,114)(H,109,132)(H,110,130)(H,112,141)(H,115,144)(H,116,131)(H,117,145)(H,118,142)(H,119,146)(H,120,143)(H,121,140)(H,134,135)(H,136,137)(H,138,139)(H,149,150)(H4,105,106,111)/t68-,69-,74-,77-,78-,79-,80-,81-,82-,84?,92-/m0/s1 QLIYIWFCLGFWMD-SQAMFPIWSA-N 50015530 CHEMBL3265322 D(2) dopamine receptor Homo sapiens 52 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656855 103927283 CHEMBL3265322 ZINC29477355 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097309 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCCC[n+]3c(C)cc(\C=C\C=C\c4ccc(cc4)N(C)C)cc3C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(O)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C169H235N37O44S/c1-10-67-204-68-31-42-114(204)92-180-150(230)117-82-112(88-132(249-8)149(117)250-9)41-32-79-251-133-91-141(219)206(166(133)246)70-27-14-21-47-136(214)197-147(103(4)208)164(244)195-127(85-108-38-19-13-20-39-108)160(240)191-126(84-107-36-17-12-18-37-107)159(239)190-124(86-109-50-56-115(210)57-51-109)152(232)181-93-137(215)179-94-138(216)184-131(100-207)163(243)185-118(45-29-65-177-168(172)173)151(231)182-95-139(217)183-119(43-24-26-64-176-140(218)96-200-71-73-201(97-144(224)225)75-77-203(99-146(228)229)78-76-202(74-72-200)98-145(226)227)153(233)186-121(46-30-66-178-169(174)175)154(234)193-128(89-134(170)212)162(242)194-129(90-135(171)213)161(241)192-125(83-106-34-15-11-16-35-106)158(238)187-120(44-25-28-69-205-101(2)80-111(81-102(205)3)40-23-22-33-105-48-54-113(55-49-105)199(6)7)157(237)198-148(104(5)209)165(245)189-123(61-63-143(222)223)155(235)188-122(60-62-142(220)221)156(236)196-130(167(247)248)87-110-52-58-116(211)59-53-110/h10-13,15-20,22-23,33-40,48-59,80-82,88,103-104,114,118-131,133,147-148,207-209H,1,14,21,24-32,41-47,60-79,83-87,89-100H2,2-9H3,(H40-,170,171,172,173,174,175,176,177,178,179,180,181,182,183,184,185,186,187,188,189,190,191,192,193,194,195,196,197,198,210,211,212,213,214,215,216,217,218,220,221,222,223,224,225,226,227,228,229,230,231,232,233,234,235,236,237,238,239,240,241,242,243,244,245,247,248)/p+1/t103-,104-,114+,118+,119+,120+,121+,122+,123+,124+,125+,126+,127+,128+,129+,130+,131+,133?,147+,148+/m1/s1 CZDGXTCLWDUEJD-BUMRKTEESA-O 50015531 CHEMBL3265323 D(2) dopamine receptor Homo sapiens 64 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656856 103927284 CHEMBL3265323 ZINC29475713 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097310 COc1cc(CCCSC2CC(=O)N(CCCCCC(=O)NCCOCCOCCOCCOCCC(N)=O)C2=O)cc(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C41H65N5O11S/c1-4-15-45-16-8-11-32(45)30-44-40(50)33-27-31(28-34(52-2)39(33)53-3)10-9-26-58-35-29-38(49)46(41(35)51)17-7-5-6-12-37(48)43-14-19-55-21-23-57-25-24-56-22-20-54-18-13-36(42)47/h4,27-28,32,35H,1,5-26,29-30H2,2-3H3,(H2,42,47)(H,43,48)(H,44,50)/t32-,35?/m0/s1 YWGNZIZBLUVIEC-GYXLRUHFSA-N 50015532 CHEMBL3265324 D(2) dopamine receptor Homo sapiens 7.3 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656857 103927285 CHEMBL3265324 ZINC29475717 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097311 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCNC(=O)O\N=C\c1ccc(cc1)[Si](F)(C(C)(C)C)C(C)(C)C)NC(=O)CCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)CC(SC[C@H](N)C(O)=O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C87H133FN20O22SSi/c1-10-54(2)73(79(118)104-66(44-56-22-26-60(109)27-23-56)80(119)107-35-17-20-68(107)78(117)102-64(19-16-32-95-84(90)91)76(115)105-67(83(123)124)46-59-50-93-53-98-59)106-74(113)55(3)100-77(116)65(45-58-49-92-52-97-58)103-75(114)63(18-13-14-31-96-85(125)130-99-48-57-24-28-61(29-25-57)132(88,86(4,5)6)87(7,8)9)101-71(111)30-36-126-38-40-128-42-43-129-41-39-127-37-33-94-70(110)21-12-11-15-34-108-72(112)47-69(81(108)120)131-51-62(89)82(121)122/h22-29,48-50,52-55,62-69,73,109H,10-21,30-47,51,89H2,1-9H3,(H,92,97)(H,93,98)(H,94,110)(H,96,125)(H,100,116)(H,101,111)(H,102,117)(H,103,114)(H,104,118)(H,105,115)(H,106,113)(H,121,122)(H,123,124)(H4,90,91,95)/b99-48+/t54-,55-,62-,63-,64-,65-,66-,67-,68-,69?,73-/m0/s1 RAARPNBMXDXXGC-KQBRWWBASA-N 50015533 CHEMBL3265325 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90656858 103927286 CHEMBL3265325 C05726 ZINC29474386 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097312 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O InChI=1S/C41H60N14O9/c1-4-22(2)33(54-34(57)23(3)50-35(58)28(42)16-25-18-45-20-48-25)38(61)52-30(15-24-9-11-27(56)12-10-24)39(62)55-14-6-8-32(55)37(60)51-29(7-5-13-47-41(43)44)36(59)53-31(40(63)64)17-26-19-46-21-49-26/h9-12,18-23,28-33,56H,4-8,13-17,42H2,1-3H3,(H,45,48)(H,46,49)(H,50,58)(H,51,60)(H,52,61)(H,53,59)(H,54,57)(H,63,64)(H4,43,44,47)/t22-,23-,28-,29-,30-,31-,32-,33-/m0/s1 XAEMVBIKWOMFAH-JIQJDAEYSA-N 50015534 CHEMBL3265326 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10169960 103927287 CHEMBL3265326 ZINC29472360 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097313 CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)C(C)C)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C55H102N20O13S/c1-30(2)29-39(50(84)73-38(22-28-89-5)52(86)75-27-12-17-40(75)53(87)88)74-47(81)33(14-7-9-24-57)68-48(82)36(18-20-41(58)76)71-46(80)35(16-11-26-66-55(63)64)69-44(78)32(13-6-8-23-56)67-45(79)34(15-10-25-65-54(61)62)70-49(83)37(19-21-42(59)77)72-51(85)43(60)31(3)4/h30-40,43H,6-29,56-57,60H2,1-5H3,(H2,58,76)(H2,59,77)(H,67,79)(H,68,82)(H,69,78)(H,70,83)(H,71,80)(H,72,85)(H,73,84)(H,74,81)(H,87,88)(H4,61,62,65)(H4,63,64,66)/t32-,33-,34-,35-,36-,37-,38-,39-,40-,43-/m0/s1 RTNFTLGNKNLZQF-IHHWSYFASA-N 50015535 CHEMBL3265327 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90643433 103927288 CHEMBL3265327 ZINC29469508 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50097314 NCCCC[C@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O InChI=1S/C52H101N27O11/c53-21-3-1-12-30(72-39(81)29(55)11-5-23-67-48(57)58)40(82)73-31(13-2-4-22-54)42(84)77-35(16-8-26-70-51(63)64)46(88)79-28-10-18-37(79)45(87)76-34(19-20-38(56)80)44(86)75-32(14-6-24-68-49(59)60)41(83)74-33(15-7-25-69-50(61)62)43(85)78-36(47(89)90)17-9-27-71-52(65)66/h29-37H,1-28,53-55H2,(H2,56,80)(H,72,81)(H,73,82)(H,74,83)(H,75,86)(H,76,87)(H,77,84)(H,78,85)(H,89,90)(H4,57,58,67)(H4,59,60,68)(H4,61,62,69)(H4,63,64,70)(H4,65,66,71)/t29-,30-,31-,32-,33-,34-,35-,36-,37-/m0/s1 XOBCYBIYOHGQPS-IZROAPMXSA-N 50015536 CHEMBL3265328 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm5004123 10.7270/Q2697543 24779610 Wängler, C; Chowdhury, S; Höfner, G; Djurova, P; Purisima, EO; Bartenstein, P; Wängler, B; Fricker, G; Wanner, KT; Schirrmacher, R McGill University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90643434 103927289 CHEMBL3265328 C04026 ZINC29475989 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101821 Cc1ccc(nc1)N1CCN(CCCOc2ccc(F)cc2)CC1 InChI=1S/C19H24FN3O/c1-16-3-8-19(21-15-16)23-12-10-22(11-13-23)9-2-14-24-18-6-4-17(20)5-7-18/h3-8,15H,2,9-14H2,1H3 VFOLOUVNAQBRDB-UHFFFAOYSA-N 50017969 CHEMBL3289646 D(2) dopamine receptor Homo sapiens 1046 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017969&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644061 242041861 CHEMBL3289646 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101824 Cc1ccc(nc1)N1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C19H24FN3S/c1-16-3-8-19(21-15-16)23-12-10-22(11-13-23)9-2-14-24-18-6-4-17(20)5-7-18/h3-8,15H,2,9-14H2,1H3 FLNJSRMYQSEHEU-UHFFFAOYSA-N 50017970 CHEMBL3289647 D(2) dopamine receptor Homo sapiens 1100 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644062 242041862 CHEMBL3289647 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101825 Cc1ccc(nc1)N1CCN(CCCCc2ccc(F)cc2)CC1 InChI=1S/C20H26FN3/c1-17-5-10-20(22-16-17)24-14-12-23(13-15-24)11-3-2-4-18-6-8-19(21)9-7-18/h5-10,16H,2-4,11-15H2,1H3 KERODJLVCVZLOA-UHFFFAOYSA-N 50017971 CHEMBL3289648 D(2) dopamine receptor Homo sapiens 1861 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017971&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644063 242041863 CHEMBL3289648 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101827 Fc1ccc(OCCCN2CCN(CC2)c2ncccn2)cc1 InChI=1S/C17H21FN4O/c18-15-3-5-16(6-4-15)23-14-2-9-21-10-12-22(13-11-21)17-19-7-1-8-20-17/h1,3-8H,2,9-14H2 FGFQEEFTBWHCLW-UHFFFAOYSA-N 50362862 CHEMBL1940417 D(2) dopamine receptor Homo sapiens 636 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57396484 136966924 CHEMBL1940417 ZINC60992903 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101828 Fc1ccc(SCCCN2CCN(CC2)c2ncccn2)cc1 InChI=1S/C17H21FN4S/c18-15-3-5-16(6-4-15)23-14-2-9-21-10-12-22(13-11-21)17-19-7-1-8-20-17/h1,3-8H,2,9-14H2 WRSUPAJSUHYUKP-UHFFFAOYSA-N 50362861 CHEMBL1940416 D(2) dopamine receptor Homo sapiens 424 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57391216 136966923 CHEMBL1940416 ZINC82158462 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101834 Fc1ccc(CCCCN2CCN(CC2)c2ncccn2)cc1 InChI=1S/C18H23FN4/c19-17-7-5-16(6-8-17)4-1-2-11-22-12-14-23(15-13-22)18-20-9-3-10-21-18/h3,5-10H,1-2,4,11-15H2 GTBFEJIEYNPFMI-UHFFFAOYSA-N 50362860 CHEMBL1940415 D(2) dopamine receptor Homo sapiens 269 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57393083 136966922 CHEMBL1940415 ZINC82158461 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101839 Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1 InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2 SCUPEGWTGGLXHI-UHFFFAOYSA-N 50384969 CHEMBL2037431 D(2) dopamine receptor Homo sapiens 219 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384969&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165416 160864052 CHEMBL2037431 ZINC84724332 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101842 Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3s2)CC1 InChI=1S/C20H22ClN3S/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2 KLXKCCCIYMYATJ-UHFFFAOYSA-N 50384968 CHEMBL2037430 D(2) dopamine receptor Homo sapiens 2321 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384968&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60167166 160864051 CHEMBL2037430 ZINC84670345 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101850 Clc1ccc(cc1)N1CCN(CCCCCc2nc3ccccc3o2)CC1 InChI=1S/C22H26ClN3O/c23-18-9-11-19(12-10-18)26-16-14-25(15-17-26)13-5-1-2-8-22-24-20-6-3-4-7-21(20)27-22/h3-4,6-7,9-12H,1-2,5,8,13-17H2 RTLWHVNMZFCSDU-UHFFFAOYSA-N 50017972 CHEMBL3289649 D(2) dopamine receptor Homo sapiens 3108 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017972&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644064 242041864 CHEMBL3289649 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103898 Clc1ccc(OCCNCCCOc2ccc(Br)cc2)cc1 InChI=1S/C17H19BrClNO2/c18-14-2-6-16(7-3-14)21-12-1-10-20-11-13-22-17-8-4-15(19)5-9-17/h2-9,20H,1,10-13H2 PFKZREOHDYTZJM-UHFFFAOYSA-N 50061341 CHEMBL128222::[3-(4-Bromo-phenoxy)-propyl]-[2-(4-chloro-phenoxy)-ethyl]-amine D(2) dopamine receptor Homo sapiens >5880 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10548105 103956903 CHEMBL128222 ZINC13766788 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103899 COc1ccc(OCCNCCCOc2ccccc2)cc1 InChI=1S/C18H23NO3/c1-20-16-8-10-18(11-9-16)22-15-13-19-12-5-14-21-17-6-3-2-4-7-17/h2-4,6-11,19H,5,12-15H2,1H3 JOCIPRSPZCLXKS-UHFFFAOYSA-N 50061343 CHEMBL128276::[2-(4-Methoxy-phenoxy)-ethyl]-(3-phenoxy-propyl)-amine D(2) dopamine receptor Homo sapiens 1950 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10518406 103956905 CHEMBL128276 ZINC13766779 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103904 Clc1ccccc1OCCNCCCOc1ccccc1 InChI=1S/C17H20ClNO2/c18-16-9-4-5-10-17(16)21-14-12-19-11-6-13-20-15-7-2-1-3-8-15/h1-5,7-10,19H,6,11-14H2 BQBVMBGNTSPRNK-UHFFFAOYSA-N 50061340 CHEMBL131396::[2-(2-Chloro-phenoxy)-ethyl]-(3-phenoxy-propyl)-amine D(2) dopamine receptor Homo sapiens 112 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780942 103956902 CHEMBL131396 ZINC13766770 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103905 [O-][N+](=O)c1ccc(OCCNCCCOc2ccccc2)cc1 InChI=1S/C17H20N2O4/c20-19(21)15-7-9-17(10-8-15)23-14-12-18-11-4-13-22-16-5-2-1-3-6-16/h1-3,5-10,18H,4,11-14H2 OVTLMIGCVPXGIF-UHFFFAOYSA-N 50061348 CHEMBL132455::[2-(4-Nitro-phenoxy)-ethyl]-(3-phenoxy-propyl)-amine D(2) dopamine receptor Homo sapiens 1400 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10805355 103956910 CHEMBL132455 ZINC13766782 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103907 Cc1cccc(OCCNCCCOc2ccccc2)c1 InChI=1S/C18H23NO2/c1-16-7-5-10-18(15-16)21-14-12-19-11-6-13-20-17-8-3-2-4-9-17/h2-5,7-10,15,19H,6,11-14H2,1H3 ACVXRXJQYWHUND-UHFFFAOYSA-N 50061351 (3-Phenoxy-propyl)-(2-m-tolyloxy-ethyl)-amine::CHEMBL128232 D(2) dopamine receptor Homo sapiens 61 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10660814 103956913 CHEMBL128232 ZINC13766777 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103911 Clc1cccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-19-4-3-5-20(21(19)23)26-13-11-25(12-14-26)9-1-2-15-28-18-7-10-27-17(16-18)6-8-24-27/h3-8,10,16H,1-2,9,11-15H2 QNWQLJBICCQPMP-UHFFFAOYSA-N 50018941 CHEMBL3287390 D(2) dopamine receptor Homo sapiens 39 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071066 103929983 CHEMBL3287390 ZINC29399049 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103912 Clc1cccc(N2CCN(CCCCOc3cccn4nccc34)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-17-5-3-6-19(21(17)23)26-14-12-25(13-15-26)10-1-2-16-28-20-7-4-11-27-18(20)8-9-24-27/h3-9,11H,1-2,10,12-16H2 WUVBFCGMNNHUHJ-UHFFFAOYSA-N 50018942 CHEMBL3287391 D(2) dopamine receptor Homo sapiens 30 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25070740 103929984 CHEMBL3287391 ZINC29402176 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103913 Clc1cccc(N2CCN(CCCCOc3ccc4ccnn4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-19-4-3-5-20(21(19)23)26-13-11-25(12-14-26)10-1-2-15-28-18-7-6-17-8-9-24-27(17)16-18/h3-9,16H,1-2,10-15H2 OUJRMAKUNWMZPB-UHFFFAOYSA-N 50018943 CHEMBL3287392 D(2) dopamine receptor Homo sapiens 2.1 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072632 103929985 CHEMBL3287392 ZINC29402182 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103914 Clc1cccc(N2CCN(CCCCOc3cccc4ccnn34)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-18-6-4-7-19(21(18)23)26-14-12-25(13-15-26)11-1-2-16-28-20-8-3-5-17-9-10-24-27(17)20/h3-10H,1-2,11-16H2 LNOVYYQKQHZPMN-UHFFFAOYSA-N 50018944 CHEMBL3287393 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072943 103929986 CHEMBL3287393 ZINC29403568 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103915 Clc1cccc(N2CCN(CCCCOc3cc4ccccn4n3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-18-7-5-8-19(21(18)23)26-13-11-25(12-14-26)9-3-4-15-28-20-16-17-6-1-2-10-27(17)24-20/h1-2,5-8,10,16H,3-4,9,11-15H2 ANOQJCMMWZANCH-UHFFFAOYSA-N 50018945 CHEMBL3287394 D(2) dopamine receptor Homo sapiens 10.0 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25070419 103929987 CHEMBL3287394 ZINC40650886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103916 CCOC(=O)c1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 InChI=1S/C24H28Cl2N4O3/c1-2-32-24(31)21-17-18-16-19(8-10-30(18)27-21)33-15-4-3-9-28-11-13-29(14-12-28)22-7-5-6-20(25)23(22)26/h5-8,10,16-17H,2-4,9,11-15H2,1H3 HXHZPLKJASKRCI-UHFFFAOYSA-N 50018946 CHEMBL3287395 D(2) dopamine receptor Homo sapiens 6.7 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644226 103929988 CHEMBL3287395 ZINC29399550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103917 OCc1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 InChI=1S/C22H26Cl2N4O2/c23-20-4-3-5-21(22(20)24)27-11-9-26(10-12-27)7-1-2-13-30-19-6-8-28-18(15-19)14-17(16-29)25-28/h3-6,8,14-15,29H,1-2,7,9-13,16H2 PIZUPLOSIUAOMH-UHFFFAOYSA-N 50018947 CHEMBL3287396 D(2) dopamine receptor Homo sapiens 2.3 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644227 103929989 CHEMBL3287396 ZINC38331970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103918 Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C=O)c4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-19-4-3-5-20(22(19)24)27-11-9-26(10-12-27)7-1-2-13-30-18-6-8-28-21(14-18)17(16-29)15-25-28/h3-6,8,14-16H,1-2,7,9-13H2 VPYCAVXBANQPPA-UHFFFAOYSA-N 50018948 CHEMBL3287397 D(2) dopamine receptor Homo sapiens 3.2 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071384 103929990 CHEMBL3287397 ZINC29400262 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103919 Clc1cccc(N2CCN(CCCCOc3cccn4ncc(C=O)c34)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-18-5-3-6-19(21(18)24)27-12-10-26(11-13-27)8-1-2-14-30-20-7-4-9-28-22(20)17(16-29)15-25-28/h3-7,9,15-16H,1-2,8,10-14H2 FESDOYDRYVULEO-UHFFFAOYSA-N 50018949 CHEMBL3287398 D(2) dopamine receptor Homo sapiens 24 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25070742 103929991 CHEMBL3287398 ZINC34802409 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103920 Clc1cccc(N2CCN(CCCCOc3ccc4c(C=O)cnn4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-19-4-3-5-21(22(19)24)27-11-9-26(10-12-27)8-1-2-13-30-18-6-7-20-17(16-29)14-25-28(20)15-18/h3-7,14-16H,1-2,8-13H2 CALYWAMIHCNUMA-UHFFFAOYSA-N 50018950 CHEMBL3287399 D(2) dopamine receptor Homo sapiens 8.1 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072635 103929992 CHEMBL3287399 ZINC29399601 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103921 Clc1cccc(N2CCN(CCCCOc3cccc4c(C=O)cnn34)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-18-5-3-7-20(22(18)24)27-12-10-26(11-13-27)9-1-2-14-30-21-8-4-6-19-17(16-29)15-25-28(19)21/h3-8,15-16H,1-2,9-14H2 ZHLBCCKGUNFWNS-UHFFFAOYSA-N 50018951 CHEMBL3287400 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072946 103929993 CHEMBL3287400 ZINC29403097 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103922 Clc1cccc(N2CCN(CCCCOc3nn4ccccc4c3C=O)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-18-6-5-8-20(21(18)24)27-13-11-26(12-14-27)9-3-4-15-30-22-17(16-29)19-7-1-2-10-28(19)25-22/h1-2,5-8,10,16H,3-4,9,11-15H2 NCIZVSJVBWAJQR-UHFFFAOYSA-N 50018952 CHEMBL3287401 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25070416 103929994 CHEMBL3287401 ZINC29396794 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103923 Clc1cccc(N2CCN(CCCCOc3ccn4nc(C=O)cc4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-20-4-3-5-21(22(20)24)27-11-9-26(10-12-27)7-1-2-13-30-19-6-8-28-18(15-19)14-17(16-29)25-28/h3-6,8,14-16H,1-2,7,9-13H2 BRJGIZVBTXYEBD-UHFFFAOYSA-N 50018953 CHEMBL3287402 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644228 103929995 CHEMBL3287402 ZINC29403092 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103924 O\N=C\c1cnn2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc12 InChI=1S/C22H25Cl2N5O2/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-31-18-6-8-29-21(14-18)17(15-25-29)16-26-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b26-16+ DWMNREQVNSYYID-WGOQTCKBSA-N 50018954 CHEMBL3287403 D(2) dopamine receptor Homo sapiens 1.7 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071691 103929996 CHEMBL3287403 C02658 ZINC29467894 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103926 O\N=C\c1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 InChI=1S/C22H25Cl2N5O2/c23-20-4-3-5-21(22(20)24)28-11-9-27(10-12-28)7-1-2-13-31-19-6-8-29-18(15-19)14-17(26-29)16-25-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b25-16+ VMDJSIGZJOXSGC-PCLIKHOPSA-N 50018955 CHEMBL3287404 D(2) dopamine receptor Homo sapiens 2.3 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644229 103929997 CHEMBL3287404 C02658 ZINC13490707 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103927 Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C#N)c4c3)CC2)c1Cl InChI=1S/C22H23Cl2N5O/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-30-18-6-8-29-21(14-18)17(15-25)16-26-29/h3-6,8,14,16H,1-2,7,9-13H2 JERZBICCWPTZQV-UHFFFAOYSA-N 50018956 CHEMBL3287405 D(2) dopamine receptor Homo sapiens 0.320000 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071692 103929998 CHEMBL3287405 ZINC29466550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103928 Clc1cccc(N2CCN(CCCCOc3ccn4nc(cc4c3)C#N)CC2)c1Cl InChI=1S/C22H23Cl2N5O/c23-20-4-3-5-21(22(20)24)28-11-9-27(10-12-28)7-1-2-13-30-19-6-8-29-18(15-19)14-17(16-25)26-29/h3-6,8,14-15H,1-2,7,9-13H2 TXMVXDBYJCUQJD-UHFFFAOYSA-N 50018957 CHEMBL3287406 D(2) dopamine receptor Homo sapiens 6.7 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644230 103929999 CHEMBL3287406 ZINC29465727 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101861 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C20H22ClFN2O/c21-17-5-9-19(10-6-17)24-14-12-23(13-15-24)11-1-2-20(25)16-3-7-18(22)8-4-16/h3-10H,1-2,11-15H2 ROKAKGMAWJNFEN-UHFFFAOYSA-N 50155520 4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one; hydrochloride::CHEMBL476935::CHEMBL558392 D(2) dopamine receptor Homo sapiens 253 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44395741 104042942 CHEMBL476935CHEMBL558392 ZINC28394173 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103965 CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 50018958 CHEBI:75401::QUINPIROLE D(2) dopamine receptor Homo sapiens 260 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 103930000 ZINC13490706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103966 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 0.540000 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103967 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17- KPWSJANDNDDRMB-QAQDUYKDSA-N 50443101 Cariprazine::RGH-188 D(2) dopamine receptor Homo sapiens 0.470000 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50443101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50443101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7RU 7VOD 11154555 194940997 DB06016 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103968 Clc1cccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-19-4-3-5-20(21(19)23)26-13-11-25(12-14-26)9-1-2-15-28-18-7-10-27-17(16-18)6-8-24-27/h3-8,10,16H,1-2,9,11-15H2 QNWQLJBICCQPMP-UHFFFAOYSA-N 50018941 CHEMBL3287390 D(2) dopamine receptor Homo sapiens 34 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071066 103929983 CHEMBL3287390 ZINC29399049 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103969 Clc1cccc(N2CCN(CCCCOc3cccn4nccc34)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-17-5-3-6-19(21(17)23)26-14-12-25(13-15-26)10-1-2-16-28-20-7-4-11-27-18(20)8-9-24-27/h3-9,11H,1-2,10,12-16H2 WUVBFCGMNNHUHJ-UHFFFAOYSA-N 50018942 CHEMBL3287391 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25070740 103929984 CHEMBL3287391 ZINC29402176 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103970 Clc1cccc(N2CCN(CCCCOc3ccc4ccnn4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-19-4-3-5-20(21(19)23)26-13-11-25(12-14-26)10-1-2-15-28-18-7-6-17-8-9-24-27(17)16-18/h3-9,16H,1-2,10-15H2 OUJRMAKUNWMZPB-UHFFFAOYSA-N 50018943 CHEMBL3287392 D(2) dopamine receptor Homo sapiens 4.2 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072632 103929985 CHEMBL3287392 ZINC29402182 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103971 Clc1cccc(N2CCN(CCCCOc3cccc4ccnn34)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-18-6-4-7-19(21(18)23)26-14-12-25(13-15-26)11-1-2-16-28-20-8-3-5-17-9-10-24-27(17)20/h3-10H,1-2,11-16H2 LNOVYYQKQHZPMN-UHFFFAOYSA-N 50018944 CHEMBL3287393 D(2) dopamine receptor Homo sapiens 64 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072943 103929986 CHEMBL3287393 ZINC29403568 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103972 Clc1cccc(N2CCN(CCCCOc3cc4ccccn4n3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-18-7-5-8-19(21(18)23)26-13-11-25(12-14-26)9-3-4-15-28-20-16-17-6-1-2-10-27(17)24-20/h1-2,5-8,10,16H,3-4,9,11-15H2 ANOQJCMMWZANCH-UHFFFAOYSA-N 50018945 CHEMBL3287394 D(2) dopamine receptor Homo sapiens 9.4 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25070419 103929987 CHEMBL3287394 ZINC40650886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103973 CCOC(=O)c1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 InChI=1S/C24H28Cl2N4O3/c1-2-32-24(31)21-17-18-16-19(8-10-30(18)27-21)33-15-4-3-9-28-11-13-29(14-12-28)22-7-5-6-20(25)23(22)26/h5-8,10,16-17H,2-4,9,11-15H2,1H3 HXHZPLKJASKRCI-UHFFFAOYSA-N 50018946 CHEMBL3287395 D(2) dopamine receptor Homo sapiens 7.4 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644226 103929988 CHEMBL3287395 ZINC29399550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103974 OCc1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 InChI=1S/C22H26Cl2N4O2/c23-20-4-3-5-21(22(20)24)27-11-9-26(10-12-27)7-1-2-13-30-19-6-8-28-18(15-19)14-17(16-29)25-28/h3-6,8,14-15,29H,1-2,7,9-13,16H2 PIZUPLOSIUAOMH-UHFFFAOYSA-N 50018947 CHEMBL3287396 D(2) dopamine receptor Homo sapiens 3.1 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644227 103929989 CHEMBL3287396 ZINC38331970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103975 Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C=O)c4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-19-4-3-5-20(22(19)24)27-11-9-26(10-12-27)7-1-2-13-30-18-6-8-28-21(14-18)17(16-29)15-25-28/h3-6,8,14-16H,1-2,7,9-13H2 VPYCAVXBANQPPA-UHFFFAOYSA-N 50018948 CHEMBL3287397 D(2) dopamine receptor Homo sapiens 4.6 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071384 103929990 CHEMBL3287397 ZINC29400262 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103976 Clc1cccc(N2CCN(CCCCOc3cccn4ncc(C=O)c34)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-18-5-3-6-19(21(18)24)27-12-10-26(11-13-27)8-1-2-14-30-20-7-4-9-28-22(20)17(16-29)15-25-28/h3-7,9,15-16H,1-2,8,10-14H2 FESDOYDRYVULEO-UHFFFAOYSA-N 50018949 CHEMBL3287398 D(2) dopamine receptor Homo sapiens 29 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25070742 103929991 CHEMBL3287398 ZINC34802409 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103977 Clc1cccc(N2CCN(CCCCOc3ccc4c(C=O)cnn4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-19-4-3-5-21(22(19)24)27-11-9-26(10-12-27)8-1-2-13-30-18-6-7-20-17(16-29)14-25-28(20)15-18/h3-7,14-16H,1-2,8-13H2 CALYWAMIHCNUMA-UHFFFAOYSA-N 50018950 CHEMBL3287399 D(2) dopamine receptor Homo sapiens 6.2 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072635 103929992 CHEMBL3287399 ZINC29399601 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103978 Clc1cccc(N2CCN(CCCCOc3cccc4c(C=O)cnn34)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-18-5-3-7-20(22(18)24)27-12-10-26(11-13-27)9-1-2-14-30-21-8-4-6-19-17(16-29)15-25-28(19)21/h3-8,15-16H,1-2,9-14H2 ZHLBCCKGUNFWNS-UHFFFAOYSA-N 50018951 CHEMBL3287400 D(2) dopamine receptor Homo sapiens 51 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072946 103929993 CHEMBL3287400 ZINC29403097 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103979 Clc1cccc(N2CCN(CCCCOc3nn4ccccc4c3C=O)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-18-6-5-8-20(21(18)24)27-13-11-26(12-14-27)9-3-4-15-30-22-17(16-29)19-7-1-2-10-28(19)25-22/h1-2,5-8,10,16H,3-4,9,11-15H2 NCIZVSJVBWAJQR-UHFFFAOYSA-N 50018952 CHEMBL3287401 D(2) dopamine receptor Homo sapiens 10.0 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25070416 103929994 CHEMBL3287401 ZINC29396794 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103980 Clc1cccc(N2CCN(CCCCOc3ccn4nc(C=O)cc4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-20-4-3-5-21(22(20)24)27-11-9-26(10-12-27)7-1-2-13-30-19-6-8-28-18(15-19)14-17(16-29)25-28/h3-6,8,14-16H,1-2,7,9-13H2 BRJGIZVBTXYEBD-UHFFFAOYSA-N 50018953 CHEMBL3287402 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644228 103929995 CHEMBL3287402 ZINC29403092 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103981 O\N=C\c1cnn2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc12 InChI=1S/C22H25Cl2N5O2/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-31-18-6-8-29-21(14-18)17(15-25-29)16-26-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b26-16+ DWMNREQVNSYYID-WGOQTCKBSA-N 50018954 CHEMBL3287403 D(2) dopamine receptor Homo sapiens 1.8 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071691 103929996 CHEMBL3287403 C02658 ZINC29467894 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103983 O\N=C\c1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 InChI=1S/C22H25Cl2N5O2/c23-20-4-3-5-21(22(20)24)28-11-9-27(10-12-28)7-1-2-13-31-19-6-8-29-18(15-19)14-17(26-29)16-25-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b25-16+ VMDJSIGZJOXSGC-PCLIKHOPSA-N 50018955 CHEMBL3287404 D(2) dopamine receptor Homo sapiens 3.3 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644229 103929997 CHEMBL3287404 C02658 ZINC13490707 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103984 Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C#N)c4c3)CC2)c1Cl InChI=1S/C22H23Cl2N5O/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-30-18-6-8-29-21(14-18)17(15-25)16-26-29/h3-6,8,14,16H,1-2,7,9-13H2 JERZBICCWPTZQV-UHFFFAOYSA-N 50018956 CHEMBL3287405 D(2) dopamine receptor Homo sapiens 0.580000 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071692 103929998 CHEMBL3287405 ZINC29466550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103985 Clc1cccc(N2CCN(CCCCOc3ccn4nc(cc4c3)C#N)CC2)c1Cl InChI=1S/C22H23Cl2N5O/c23-20-4-3-5-21(22(20)24)28-11-9-27(10-12-28)7-1-2-13-30-19-6-8-29-18(15-19)14-17(16-25)26-29/h3-6,8,14-15H,1-2,7,9-13H2 TXMVXDBYJCUQJD-UHFFFAOYSA-N 50018957 CHEMBL3287406 D(2) dopamine receptor Homo sapiens 8.9 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644230 103929999 CHEMBL3287406 ZINC29465727 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103006 COc1cccc2[C@@H]3CN(CCn4c(=O)[nH]c5c6ncccc6sc5c4=O)C[C@@H]3CCc12 InChI=1S/C24H24N4O3S/c1-31-18-5-2-4-15-16(18)8-7-14-12-27(13-17(14)15)10-11-28-23(29)22-21(26-24(28)30)20-19(32-22)6-3-9-25-20/h2-6,9,14,17H,7-8,10-13H2,1H3,(H,26,30)/t14-,17+/m0/s1 OLPQNRLJYOGSGV-WMLDXEAASA-N 50060965 2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione::2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,6-triaza-fluorene-1,3-dione::2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione::A-131701::CHEMBL40650 D(2) dopamine receptor Homo sapiens 19.7 ChEMBL 10.1021/jm970364a 10.7270/Q2R78DBB 9379432 Meyer, MD; Altenbach, RJ; Basha, FZ; Carroll, WA; Drizin, I; Elmore, SW; Ehrlich, PP; Lebold, SA; Tietje, K; Sippy, KB; Wendt, MD; Plata, DJ; Plagge, F; Buckner, SA; Brune, ME; Hancock, AA; Kerwin, JF Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10527469 103956571 CHEMBL40650 ZINC25422025 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104054 CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 50018958 CHEBI:75401::QUINPIROLE D(2) dopamine receptor Homo sapiens 70 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 103930000 ZINC13490706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104110 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 0.450000 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104114 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17- KPWSJANDNDDRMB-QAQDUYKDSA-N 50443101 Cariprazine::RGH-188 D(2) dopamine receptor Homo sapiens 0.410000 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50443101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50443101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7RU 7VOD 11154555 194940997 DB06016 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104159 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104160 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17- KPWSJANDNDDRMB-QAQDUYKDSA-N 50443101 Cariprazine::RGH-188 D(2) dopamine receptor Homo sapiens 1.7 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50443101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50443101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7RU 7VOD 11154555 194940997 DB06016 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104167 Clc1cccc(N2CCN(CCCCOc3ccn4nc(C=O)cc4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-20-4-3-5-21(22(20)24)27-11-9-26(10-12-27)7-1-2-13-30-19-6-8-28-18(15-19)14-17(16-29)25-28/h3-6,8,14-16H,1-2,7,9-13H2 BRJGIZVBTXYEBD-UHFFFAOYSA-N 50018953 CHEMBL3287402 D(2) dopamine receptor Homo sapiens 29 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644228 103929995 CHEMBL3287402 ZINC29403092 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104168 O\N=C\c1cnn2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc12 InChI=1S/C22H25Cl2N5O2/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-31-18-6-8-29-21(14-18)17(15-25-29)16-26-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b26-16+ DWMNREQVNSYYID-WGOQTCKBSA-N 50018954 CHEMBL3287403 D(2) dopamine receptor Homo sapiens 3.8 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071691 103929996 CHEMBL3287403 C02658 ZINC29467894 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104174 Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C=O)c4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-19-4-3-5-20(22(19)24)27-11-9-26(10-12-27)7-1-2-13-30-18-6-8-28-21(14-18)17(16-29)15-25-28/h3-6,8,14-16H,1-2,7,9-13H2 VPYCAVXBANQPPA-UHFFFAOYSA-N 50018948 CHEMBL3287397 D(2) dopamine receptor Homo sapiens 360 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071384 103929990 CHEMBL3287397 ZINC29400262 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104183 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.700000 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104184 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17- KPWSJANDNDDRMB-QAQDUYKDSA-N 50443101 Cariprazine::RGH-188 D(2) dopamine receptor Homo sapiens 3.5 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50443101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50443101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7RU 7VOD 11154555 194940997 DB06016 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102147 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 0.040000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102184 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Homo sapiens 5.0 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104219 Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C#N)c4c3)CC2)c1Cl InChI=1S/C22H23Cl2N5O/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-30-18-6-8-29-21(14-18)17(15-25)16-26-29/h3-6,8,14,16H,1-2,7,9-13H2 JERZBICCWPTZQV-UHFFFAOYSA-N 50018956 CHEMBL3287405 D(2) dopamine receptor Homo sapiens 110 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071692 103929998 CHEMBL3287405 ZINC29466550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104220 Clc1cccc(N2CCN(CCCCOc3ccn4nc(cc4c3)C#N)CC2)c1Cl InChI=1S/C22H23Cl2N5O/c23-20-4-3-5-21(22(20)24)28-11-9-27(10-12-28)7-1-2-13-30-19-6-8-29-18(15-19)14-17(16-25)26-29/h3-6,8,14-15H,1-2,7,9-13H2 TXMVXDBYJCUQJD-UHFFFAOYSA-N 50018957 CHEMBL3287406 D(2) dopamine receptor Homo sapiens 98 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644230 103929999 CHEMBL3287406 ZINC29465727 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104223 CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 50018958 CHEBI:75401::QUINPIROLE D(2) dopamine receptor Homo sapiens 1600 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 103930000 ZINC13490706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104224 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Homo sapiens 160 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104225 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17- KPWSJANDNDDRMB-QAQDUYKDSA-N 50443101 Cariprazine::RGH-188 D(2) dopamine receptor Homo sapiens 110 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50443101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50443101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7RU 7VOD 11154555 194940997 DB06016 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104226 Clc1cccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-19-4-3-5-20(21(19)23)26-13-11-25(12-14-26)9-1-2-15-28-18-7-10-27-17(16-18)6-8-24-27/h3-8,10,16H,1-2,9,11-15H2 QNWQLJBICCQPMP-UHFFFAOYSA-N 50018941 CHEMBL3287390 D(2) dopamine receptor Homo sapiens 180 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071066 103929983 CHEMBL3287390 ZINC29399049 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104227 Clc1cccc(N2CCN(CCCCOc3ccc4ccnn4c3)CC2)c1Cl InChI=1S/C21H24Cl2N4O/c22-19-4-3-5-20(21(19)23)26-13-11-25(12-14-26)10-1-2-15-28-18-7-6-17-8-9-24-27(17)16-18/h3-9,16H,1-2,10-15H2 OUJRMAKUNWMZPB-UHFFFAOYSA-N 50018943 CHEMBL3287392 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072632 103929985 CHEMBL3287392 ZINC29402182 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104228 CCOC(=O)c1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 InChI=1S/C24H28Cl2N4O3/c1-2-32-24(31)21-17-18-16-19(8-10-30(18)27-21)33-15-4-3-9-28-11-13-29(14-12-28)22-7-5-6-20(25)23(22)26/h5-8,10,16-17H,2-4,9,11-15H2,1H3 HXHZPLKJASKRCI-UHFFFAOYSA-N 50018946 CHEMBL3287395 D(2) dopamine receptor Homo sapiens 440 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644226 103929988 CHEMBL3287395 ZINC29399550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104229 OCc1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 InChI=1S/C22H26Cl2N4O2/c23-20-4-3-5-21(22(20)24)27-11-9-26(10-12-27)7-1-2-13-30-19-6-8-28-18(15-19)14-17(16-29)25-28/h3-6,8,14-15,29H,1-2,7,9-13,16H2 PIZUPLOSIUAOMH-UHFFFAOYSA-N 50018947 CHEMBL3287396 D(2) dopamine receptor Homo sapiens 540 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644227 103929989 CHEMBL3287396 ZINC38331970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104241 Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C=O)c4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-19-4-3-5-20(22(19)24)27-11-9-26(10-12-27)7-1-2-13-30-18-6-8-28-21(14-18)17(16-29)15-25-28/h3-6,8,14-16H,1-2,7,9-13H2 VPYCAVXBANQPPA-UHFFFAOYSA-N 50018948 CHEMBL3287397 D(2) dopamine receptor Homo sapiens 650 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071384 103929990 CHEMBL3287397 ZINC29400262 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104244 Clc1cccc(N2CCN(CCCCOc3ccc4c(C=O)cnn4c3)CC2)c1Cl InChI=1S/C22H24Cl2N4O2/c23-19-4-3-5-21(22(19)24)27-11-9-26(10-12-27)8-1-2-13-30-18-6-7-20-17(16-29)14-25-28(20)15-18/h3-7,14-16H,1-2,8-13H2 CALYWAMIHCNUMA-UHFFFAOYSA-N 50018950 CHEMBL3287399 D(2) dopamine receptor Homo sapiens 340 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25072635 103929992 CHEMBL3287399 ZINC29399601 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104256 O\N=C\c1cnn2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc12 InChI=1S/C22H25Cl2N5O2/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-31-18-6-8-29-21(14-18)17(15-25-29)16-26-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b26-16+ DWMNREQVNSYYID-WGOQTCKBSA-N 50018954 CHEMBL3287403 D(2) dopamine receptor Homo sapiens 270 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25071691 103929996 CHEMBL3287403 C02658 ZINC29467894 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102191 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 4.0 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50104273 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 470 ChEMBL 10.1021/jm5004039 10.7270/Q2SN0BH5 24831693 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102306 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cnc3ccccn23)CC1 InChI=1S/C23H26FN5O3S/c24-18-6-7-19-20(15-18)32-27-23(19)17-8-13-28(14-9-17)11-4-2-10-26-33(30,31)22-16-25-21-5-1-3-12-29(21)22/h1,3,5-7,12,15-17,26H,2,4,8-11,13-14H2 PDHFVQWVURJQTK-UHFFFAOYSA-N 50018253 CHEMBL3290019 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801246 103929409 CHEMBL3290019 ZINC36272611 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102307 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2cccc3scnc23)CC1 InChI=1S/C22H23FN4O3S2/c23-16-5-6-17-18(13-16)30-26-21(17)15-7-11-27(12-8-15)10-2-9-25-32(28,29)20-4-1-3-19-22(20)24-14-31-19/h1,3-6,13-15,25H,2,7-12H2 IJJVMTLWQBMFNW-UHFFFAOYSA-N 50018254 CHEMBL3290020 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801565 103929410 CHEMBL3290020 ZINC04018123 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102308 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cccc3scnc23)CC1 InChI=1S/C23H25FN4O3S2/c24-17-6-7-18-19(14-17)31-27-22(18)16-8-12-28(13-9-16)11-2-1-10-26-33(29,30)21-5-3-4-20-23(21)25-15-32-20/h3-7,14-16,26H,1-2,8-13H2 ZLGZCZCALIKICJ-UHFFFAOYSA-N 50018255 CHEMBL3290021 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944473 103929411 CHEMBL3290021 ZINC36272672 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102314 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cc3ccccc3s2)CC1 InChI=1S/C24H26FN3O3S2/c25-19-7-8-20-21(16-19)31-27-24(20)17-9-13-28(14-10-17)12-4-3-11-26-33(29,30)23-15-18-5-1-2-6-22(18)32-23/h1-2,5-8,15-17,26H,3-4,9-14H2 GXZWKZAOGQRNTL-UHFFFAOYSA-N 50018019 CHEMBL3290012 D(2) dopamine receptor Homo sapiens 1.8 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944383 103929195 CHEMBL3290012 ZINC28102656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102367 Cc1cccc(c1)S(=O)(=O)NCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C20H24N4O2S2/c1-16-5-4-6-17(15-16)28(25,26)21-9-10-23-11-13-24(14-12-23)20-18-7-2-3-8-19(18)27-22-20/h2-8,15,21H,9-14H2,1H3 IHUSAUOGQDOBGQ-UHFFFAOYSA-N 50018020 CHEMBL3289708 D(2) dopamine receptor Homo sapiens 43 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800942 103929196 CHEMBL3289708 ZINC28094789 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102369 Cc1cccc(c1)S(=O)(=O)NCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H26N4O2S2/c1-17-6-4-7-18(16-17)29(26,27)22-10-5-11-24-12-14-25(15-13-24)21-19-8-2-3-9-20(19)28-23-21/h2-4,6-9,16,22H,5,10-15H2,1H3 PPDKTZHRAFOGEZ-UHFFFAOYSA-N 50018021 CHEMBL3289709 D(2) dopamine receptor Homo sapiens 13 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801107 103929197 CHEMBL3289709 ZINC28102429 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102370 Cc1cccc(c1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H28N4O2S2/c1-18-7-6-8-19(17-18)30(27,28)23-11-4-5-12-25-13-15-26(16-14-25)22-20-9-2-3-10-21(20)29-24-22/h2-3,6-10,17,23H,4-5,11-16H2,1H3 GCISKOCCNUBHDG-UHFFFAOYSA-N 50018022 CHEMBL3289944 D(2) dopamine receptor Homo sapiens 8.7 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018022&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944565 103929198 CHEMBL3289944 ZINC28017965 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102371 Clc1ccc(cc1Cl)S(=O)(=O)NCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C20H22Cl2N4O2S2/c21-17-7-6-15(14-18(17)22)30(27,28)23-8-3-9-25-10-12-26(13-11-25)20-16-4-1-2-5-19(16)29-24-20/h1-2,4-7,14,23H,3,8-13H2 NJTCYGAQRADUAS-UHFFFAOYSA-N 50018023 CHEMBL3289945 D(2) dopamine receptor Homo sapiens 7.8 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018023&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801613 103929199 CHEMBL3289945 ZINC28105688 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102372 Clc1ccc(cc1Cl)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H24Cl2N4O2S2/c22-18-8-7-16(15-19(18)23)31(28,29)24-9-3-4-10-26-11-13-27(14-12-26)21-17-5-1-2-6-20(17)30-25-21/h1-2,5-8,15,24H,3-4,9-14H2 FBKYNXBETLTSPE-UHFFFAOYSA-N 50018024 CHEMBL3289946 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56943891 103929200 CHEMBL3289946 ZINC28093034 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102373 Fc1ccc(cc1Cl)S(=O)(=O)NCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C20H22ClFN4O2S2/c21-17-14-15(6-7-18(17)22)30(27,28)23-8-3-9-25-10-12-26(13-11-25)20-16-4-1-2-5-19(16)29-24-20/h1-2,4-7,14,23H,3,8-13H2 FOBZBVWBEVBZHU-UHFFFAOYSA-N 50018025 CHEMBL3289947 D(2) dopamine receptor Homo sapiens 37 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801160 103929201 CHEMBL3289947 ZINC28096397 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102374 Fc1ccc(cc1Cl)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H24ClFN4O2S2/c22-18-15-16(7-8-19(18)23)31(28,29)24-9-3-4-10-26-11-13-27(14-12-26)21-17-5-1-2-6-20(17)30-25-21/h1-2,5-8,15,24H,3-4,9-14H2 OQWYJSDRCMFVSW-UHFFFAOYSA-N 50018026 CHEMBL3286432 D(2) dopamine receptor Homo sapiens 39 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801140 103929202 CHEMBL3286432 ZINC28105389 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102433 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H23F3N4O3S2/c22-21(23,24)31-16-6-8-17(9-7-16)33(29,30)25-10-3-11-27-12-14-28(15-13-27)20-18-4-1-2-5-19(18)32-26-20/h1-2,4-9,25H,3,10-15H2 CBJLKVBQMMAZQJ-UHFFFAOYSA-N 50018027 CHEMBL3289948 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801335 103929203 CHEMBL3289948 ZINC00597041 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102434 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H25F3N4O3S2/c23-22(24,25)32-17-7-9-18(10-8-17)34(30,31)26-11-3-4-12-28-13-15-29(16-14-28)21-19-5-1-2-6-20(19)33-27-21/h1-2,5-10,26H,3-4,11-16H2 PXFNUVRXAKDHRD-UHFFFAOYSA-N 50018028 CHEMBL3289949 D(2) dopamine receptor Homo sapiens 48 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800934 103929204 CHEMBL3289949 ZINC28021197 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102435 O=S(=O)(NCCCN1CCN(CC1)c1nsc2ccccc12)c1cccs1 InChI=1S/C18H22N4O2S3/c23-27(24,17-7-3-14-25-17)19-8-4-9-21-10-12-22(13-11-21)18-15-5-1-2-6-16(15)26-20-18/h1-3,5-7,14,19H,4,8-13H2 KKOAHOJCVVPWLC-UHFFFAOYSA-N 50018029 CHEMBL3289950 D(2) dopamine receptor Homo sapiens 56 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018029&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68281136 103929205 CHEMBL3289950 ZINC28096063 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102436 O=S(=O)(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccs1 InChI=1S/C19H24N4O2S3/c24-28(25,18-8-5-15-26-18)20-9-3-4-10-22-11-13-23(14-12-22)19-16-6-1-2-7-17(16)27-21-19/h1-2,5-8,15,20H,3-4,9-14H2 VNEIHMUMEPSZBA-UHFFFAOYSA-N 50018030 CHEMBL3289951 D(2) dopamine receptor Homo sapiens 3.2 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801230 103929206 CHEMBL3289951 ZINC28091643 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102437 O=S(=O)(NCCN1CCN(CC1)c1nsc2ccccc12)c1ccc2ccccc2c1 InChI=1S/C23H24N4O2S2/c28-31(29,20-10-9-18-5-1-2-6-19(18)17-20)24-11-12-26-13-15-27(16-14-26)23-21-7-3-4-8-22(21)30-25-23/h1-10,17,24H,11-16H2 MRQHTSWENGWSMD-UHFFFAOYSA-N 50018031 CHEMBL3289952 D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801229 103929207 CHEMBL3289952 ZINC28089587 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102438 O=S(=O)(NCCCN1CCN(CC1)c1nsc2ccccc12)c1ccc2ccccc2c1 InChI=1S/C24H26N4O2S2/c29-32(30,21-11-10-19-6-1-2-7-20(19)18-21)25-12-5-13-27-14-16-28(17-15-27)24-22-8-3-4-9-23(22)31-26-24/h1-4,6-11,18,25H,5,12-17H2 XILFFKQSRRILNP-UHFFFAOYSA-N 50018032 CHEMBL3289953 D(2) dopamine receptor Homo sapiens 2.2 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800939 103929208 CHEMBL3289953 ZINC28099212 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102439 O=S(=O)(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1ccc2ccccc2c1 InChI=1S/C25H28N4O2S2/c30-33(31,22-12-11-20-7-1-2-8-21(20)19-22)26-13-5-6-14-28-15-17-29(18-16-28)25-23-9-3-4-10-24(23)32-27-25/h1-4,7-12,19,26H,5-6,13-18H2 RCWSDRYOQJIECB-UHFFFAOYSA-N 50018033 CHEMBL3289954 D(2) dopamine receptor Homo sapiens 0.900000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944564 103929209 CHEMBL3289954 ZINC28018256 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102440 Clc1ccc2cc(ccc2c1)S(=O)(=O)NCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H25ClN4O2S2/c25-20-8-6-19-17-21(9-7-18(19)16-20)33(30,31)26-10-3-11-28-12-14-29(15-13-28)24-22-4-1-2-5-23(22)32-27-24/h1-2,4-9,16-17,26H,3,10-15H2 HKXKURPRSDNOEE-UHFFFAOYSA-N 50018034 CHEMBL3289955 D(2) dopamine receptor Homo sapiens 6.0 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56945046 103929210 CHEMBL3289955 ZINC28016750 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102441 Clc1ccc2cc(ccc2c1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C25H27ClN4O2S2/c26-21-9-7-20-18-22(10-8-19(20)17-21)34(31,32)27-11-3-4-12-29-13-15-30(16-14-29)25-23-5-1-2-6-24(23)33-28-25/h1-2,5-10,17-18,27H,3-4,11-16H2 YASIAEWQHNEVDZ-UHFFFAOYSA-N 50018035 CHEMBL3289956 D(2) dopamine receptor Homo sapiens 49 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56945045 103929211 CHEMBL3289956 ZINC28022336 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102442 O=S(=O)(NCCCN1CCN(CC1)c1nsc2ccccc12)c1cc2ccccc2s1 InChI=1S/C22H24N4O2S3/c27-31(28,21-16-17-6-1-3-8-19(17)29-21)23-10-5-11-25-12-14-26(15-13-25)22-18-7-2-4-9-20(18)30-24-22/h1-4,6-9,16,23H,5,10-15H2 MDQMLURYMYEWDH-UHFFFAOYSA-N 50018036 CHEMBL3289957 D(2) dopamine receptor Homo sapiens 48 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801000 103929212 CHEMBL3289957 ZINC28099135 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102443 O=S(=O)(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cc2ccccc2s1 InChI=1S/C23H26N4O2S3/c28-32(29,22-17-18-7-1-3-9-20(18)30-22)24-11-5-6-12-26-13-15-27(16-14-26)23-19-8-2-4-10-21(19)31-25-23/h1-4,7-10,17,24H,5-6,11-16H2 XKMZCZXGCDUIMM-UHFFFAOYSA-N 50018037 CHEMBL3289958 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801173 103929213 CHEMBL3289958 ZINC28085979 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102444 Clc1ccc2cc(sc2c1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H25ClN4O2S3/c24-18-8-7-17-15-22(31-21(17)16-18)33(29,30)25-9-3-4-10-27-11-13-28(14-12-27)23-19-5-1-2-6-20(19)32-26-23/h1-2,5-8,15-16,25H,3-4,9-14H2 JJLIADRRWNTBBL-UHFFFAOYSA-N 50018039 CHEMBL3289960 D(2) dopamine receptor Homo sapiens 45 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801605 103929215 CHEMBL3289960 ZINC28016746 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102445 Cc1c(sc2ccc(F)cc12)S(=O)(=O)NCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H25FN4O2S3/c1-16-19-15-17(24)7-8-20(19)31-23(16)33(29,30)25-9-4-10-27-11-13-28(14-12-27)22-18-5-2-3-6-21(18)32-26-22/h2-3,5-8,15,25H,4,9-14H2,1H3 UVIRMXOGFYHFJB-UHFFFAOYSA-N 50018040 CHEMBL3289961 D(2) dopamine receptor Homo sapiens 8.3 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018040&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800823 103929216 CHEMBL3289961 ZINC28020338 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102446 Cc1c(sc2ccc(F)cc12)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H27FN4O2S3/c1-17-20-16-18(25)8-9-21(20)32-24(17)34(30,31)26-10-4-5-11-28-12-14-29(15-13-28)23-19-6-2-3-7-22(19)33-27-23/h2-3,6-9,16,26H,4-5,10-15H2,1H3 OIEGDDBPBCGRNO-UHFFFAOYSA-N 50018041 CHEMBL3289962 D(2) dopamine receptor Homo sapiens 44 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800916 103929217 CHEMBL3289962 ZINC28013419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102447 O=S(=O)(NCCCN1CCN(CC1)c1nsc2ccccc12)c1cnc2ccccn12 InChI=1S/C21H24N6O2S2/c28-31(29,20-16-22-19-8-3-4-11-27(19)20)23-9-5-10-25-12-14-26(15-13-25)21-17-6-1-2-7-18(17)30-24-21/h1-4,6-8,11,16,23H,5,9-10,12-15H2 YXPPQEAUYCKYSO-UHFFFAOYSA-N 50018042 CHEMBL3289963 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018042&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800991 103929218 CHEMBL3289963 ZINC28022384 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102448 O=S(=O)(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cnc2ccccn12 InChI=1S/C22H26N6O2S2/c29-32(30,21-17-23-20-9-3-5-12-28(20)21)24-10-4-6-11-26-13-15-27(16-14-26)22-18-7-1-2-8-19(18)31-25-22/h1-3,5,7-9,12,17,24H,4,6,10-11,13-16H2 IWCRACLNBWLIAL-UHFFFAOYSA-N 50018043 CHEMBL3289964 D(2) dopamine receptor Homo sapiens 46 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801455 103929219 CHEMBL3289964 ZINC28101490 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102449 O=S(=O)(NCCCN1CCN(CC1)c1nsc2ccccc12)c1cccc2scnc12 InChI=1S/C21H23N5O2S3/c27-31(28,19-8-3-7-18-20(19)22-15-29-18)23-9-4-10-25-11-13-26(14-12-25)21-16-5-1-2-6-17(16)30-24-21/h1-3,5-8,15,23H,4,9-14H2 SCCJGBCCPYUPOB-UHFFFAOYSA-N 50018044 CHEMBL3289965 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800909 103929220 CHEMBL3289965 ZINC28094783 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102450 O=S(=O)(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccc2scnc12 InChI=1S/C22H25N5O2S3/c28-32(29,20-9-5-8-19-21(20)23-16-30-19)24-10-3-4-11-26-12-14-27(15-13-26)22-17-6-1-2-7-18(17)31-25-22/h1-2,5-9,16,24H,3-4,10-15H2 YQHLZLIFZLFKSH-UHFFFAOYSA-N 50018045 CHEMBL3289966 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801379 103929221 CHEMBL3289966 ZINC28094936 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102451 Cc1cccc(c1)S(=O)(=O)NCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C21H26N4O3S/c1-17-6-4-7-18(16-17)29(26,27)22-10-5-11-24-12-14-25(15-13-24)21-19-8-2-3-9-20(19)28-23-21/h2-4,6-9,16,22H,5,10-15H2,1H3 NYRDAOIKGSCMQF-UHFFFAOYSA-N 50018046 CHEMBL3289967 D(2) dopamine receptor Homo sapiens 2000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644074 103929222 CHEMBL3289967 ZINC28018020 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102452 Cc1cccc(c1)S(=O)(=O)NCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C22H28N4O3S/c1-18-7-6-8-19(17-18)30(27,28)23-11-4-5-12-25-13-15-26(16-14-25)22-20-9-2-3-10-21(20)29-24-22/h2-3,6-10,17,23H,4-5,11-16H2,1H3 UGKBAMPEXOAPEC-UHFFFAOYSA-N 50018047 CHEMBL3289968 D(2) dopamine receptor Homo sapiens 44 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944664 103929223 CHEMBL3289968 ZINC28016785 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102453 Clc1ccc(cc1Cl)S(=O)(=O)NCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C20H22Cl2N4O3S/c21-17-7-6-15(14-18(17)22)30(27,28)23-8-3-9-25-10-12-26(13-11-25)20-16-4-1-2-5-19(16)29-24-20/h1-2,4-7,14,23H,3,8-13H2 OEUUOVONAQZIBE-UHFFFAOYSA-N 50018048 CHEMBL3289969 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801673 103929224 CHEMBL3289969 ZINC28017749 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102454 Clc1ccc(cc1Cl)S(=O)(=O)NCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C21H24Cl2N4O3S/c22-18-8-7-16(15-19(18)23)31(28,29)24-9-3-4-10-26-11-13-27(14-12-26)21-17-5-1-2-6-20(17)30-25-21/h1-2,5-8,15,24H,3-4,9-14H2 ZWISNUUPDBRYSY-UHFFFAOYSA-N 50018049 CHEMBL3289970 D(2) dopamine receptor Homo sapiens 57 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801263 103929225 CHEMBL3289970 ZINC28104545 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102455 Fc1ccc(cc1Cl)S(=O)(=O)NCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C20H22ClFN4O3S/c21-17-14-15(6-7-18(17)22)30(27,28)23-8-3-9-25-10-12-26(13-11-25)20-16-4-1-2-5-19(16)29-24-20/h1-2,4-7,14,23H,3,8-13H2 WPDFUYMLDBHNAG-UHFFFAOYSA-N 50018050 CHEMBL3289971 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801226 103929226 CHEMBL3289971 ZINC28085740 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102456 Fc1ccc(cc1Cl)S(=O)(=O)NCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C21H24ClFN4O3S/c22-18-15-16(7-8-19(18)23)31(28,29)24-9-3-4-10-26-11-13-27(14-12-26)21-17-5-1-2-6-20(17)30-25-21/h1-2,5-8,15,24H,3-4,9-14H2 RHNJWNWKMNDAAR-UHFFFAOYSA-N 50018051 CHEMBL3289972 D(2) dopamine receptor Homo sapiens 77 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944082 103929227 CHEMBL3289972 ZINC28107526 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102457 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C21H23F3N4O4S/c22-21(23,24)31-16-6-8-17(9-7-16)33(29,30)25-10-3-11-27-12-14-28(15-13-27)20-18-4-1-2-5-19(18)32-26-20/h1-2,4-9,25H,3,10-15H2 MOXRKUZTWOCHHC-UHFFFAOYSA-N 50018052 CHEMBL3289973 D(2) dopamine receptor Homo sapiens 63 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644075 103929228 CHEMBL3289973 ZINC28103156 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102458 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C22H25F3N4O4S/c23-22(24,25)32-17-7-9-18(10-8-17)34(30,31)26-11-3-4-12-28-13-15-29(16-14-28)21-19-5-1-2-6-20(19)33-27-21/h1-2,5-10,26H,3-4,11-16H2 XCQOYNXZUPVYAF-UHFFFAOYSA-N 50018053 CHEMBL3289974 D(2) dopamine receptor Homo sapiens 400 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68281137 103929229 CHEMBL3289974 ZINC28007501 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102459 O=S(=O)(NCCCN1CCN(CC1)c1noc2ccccc12)c1cccs1 InChI=1S/C18H22N4O3S2/c23-27(24,17-7-3-14-26-17)19-8-4-9-21-10-12-22(13-11-21)18-15-5-1-2-6-16(15)25-20-18/h1-3,5-7,14,19H,4,8-13H2 VIYCCCHLLWDXDN-UHFFFAOYSA-N 50018054 CHEMBL3289975 D(2) dopamine receptor Homo sapiens 55 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644076 103929230 CHEMBL3289975 ZINC28092557 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102460 O=S(=O)(NCCCCN1CCN(CC1)c1noc2ccccc12)c1cccs1 InChI=1S/C19H24N4O3S2/c24-28(25,18-8-5-15-27-18)20-9-3-4-10-22-11-13-23(14-12-22)19-16-6-1-2-7-17(16)26-21-19/h1-2,5-8,15,20H,3-4,9-14H2 QOUKQMLUTNKYNS-UHFFFAOYSA-N 50018107 CHEMBL3289976 D(2) dopamine receptor Homo sapiens 5.3 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944086 103929283 CHEMBL3289976 ZINC28231305 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102461 O=S(=O)(NCCCN1CCN(CC1)c1noc2ccccc12)c1ccc2ccccc2c1 InChI=1S/C24H26N4O3S/c29-32(30,21-11-10-19-6-1-2-7-20(19)18-21)25-12-5-13-27-14-16-28(17-15-27)24-22-8-3-4-9-23(22)31-26-24/h1-4,6-11,18,25H,5,12-17H2 CJGUBEHBJWODAS-UHFFFAOYSA-N 50018189 CHEMBL3289977 D(2) dopamine receptor Homo sapiens 7200 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018189&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801354 242041870 CHEMBL3289977 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102462 O=S(=O)(NCCCCN1CCN(CC1)c1noc2ccccc12)c1ccc2ccccc2c1 InChI=1S/C25H28N4O3S/c30-33(31,22-12-11-20-7-1-2-8-21(20)19-22)26-13-5-6-14-28-15-17-29(18-16-28)25-23-9-3-4-10-24(23)32-27-25/h1-4,7-12,19,26H,5-6,13-18H2 YKTBDLSRILDSHB-UHFFFAOYSA-N 50018190 CHEMBL3289978 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018190&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801158 242041871 CHEMBL3289978 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102463 Clc1ccc2cc(ccc2c1)S(=O)(=O)NCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C24H25ClN4O3S/c25-20-8-6-19-17-21(9-7-18(19)16-20)33(30,31)26-10-3-11-28-12-14-29(15-13-28)24-22-4-1-2-5-23(22)32-27-24/h1-2,4-9,16-17,26H,3,10-15H2 JRESDQOKKZYZGG-UHFFFAOYSA-N 50018191 CHEMBL3289979 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018191&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801267 242041872 CHEMBL3289979 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102464 Clc1ccc2cc(ccc2c1)S(=O)(=O)NCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C25H27ClN4O3S/c26-21-9-7-20-18-22(10-8-19(20)17-21)34(31,32)27-11-3-4-12-29-13-15-30(16-14-29)25-23-5-1-2-6-24(23)33-28-25/h1-2,5-10,17-18,27H,3-4,11-16H2 OYNMVCMJTOXTRN-UHFFFAOYSA-N 50018192 CHEMBL3289980 D(2) dopamine receptor Homo sapiens 51 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56943599 242041873 CHEMBL3289980 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102465 O=S(=O)(NCCCN1CCN(CC1)c1noc2ccccc12)c1cc2ccccc2s1 InChI=1S/C22H24N4O3S2/c27-31(28,21-16-17-6-1-4-9-20(17)30-21)23-10-5-11-25-12-14-26(15-13-25)22-18-7-2-3-8-19(18)29-24-22/h1-4,6-9,16,23H,5,10-15H2 DCFQCUAMUNSALM-UHFFFAOYSA-N 50018193 CHEMBL3289981 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018193&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644077 242041874 CHEMBL3289981 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102466 O=S(=O)(NCCCCN1CCN(CC1)c1noc2ccccc12)c1cc2ccccc2s1 InChI=1S/C23H26N4O3S2/c28-32(29,22-17-18-7-1-4-10-21(18)31-22)24-11-5-6-12-26-13-15-27(16-14-26)23-19-8-2-3-9-20(19)30-25-23/h1-4,7-10,17,24H,5-6,11-16H2 JYPDEXJCUSDKRF-UHFFFAOYSA-N 50018194 CHEMBL3289982 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018194&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801333 242041875 CHEMBL3289982 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102467 Clc1ccc2cc(sc2c1)S(=O)(=O)NCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C22H23ClN4O3S2/c23-17-7-6-16-14-21(31-20(16)15-17)32(28,29)24-8-3-9-26-10-12-27(13-11-26)22-18-4-1-2-5-19(18)30-25-22/h1-2,4-7,14-15,24H,3,8-13H2 UYSWWUHGOKVFCN-UHFFFAOYSA-N 50018195 CHEMBL3289983 D(2) dopamine receptor Homo sapiens 30 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644078 242041876 CHEMBL3289983 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102468 Clc1ccc2cc(sc2c1)S(=O)(=O)NCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C23H25ClN4O3S2/c24-18-8-7-17-15-22(32-21(17)16-18)33(29,30)25-9-3-4-10-27-11-13-28(14-12-27)23-19-5-1-2-6-20(19)31-26-23/h1-2,5-8,15-16,25H,3-4,9-14H2 HVNIAEADLPQYLQ-UHFFFAOYSA-N 50018196 CHEMBL3289984 D(2) dopamine receptor Homo sapiens 54 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018196&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944186 242041877 CHEMBL3289984 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102469 Cc1c(sc2ccc(F)cc12)S(=O)(=O)NCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C23H25FN4O3S2/c1-16-19-15-17(24)7-8-21(19)32-23(16)33(29,30)25-9-4-10-27-11-13-28(14-12-27)22-18-5-2-3-6-20(18)31-26-22/h2-3,5-8,15,25H,4,9-14H2,1H3 ILLBBUJFUQIJOT-UHFFFAOYSA-N 50018197 CHEMBL3289985 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800926 242041878 CHEMBL3289985 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102470 Cc1c(sc2ccc(F)cc12)S(=O)(=O)NCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C24H27FN4O3S2/c1-17-20-16-18(25)8-9-22(20)33-24(17)34(30,31)26-10-4-5-11-28-12-14-29(15-13-28)23-19-6-2-3-7-21(19)32-27-23/h2-3,6-9,16,26H,4-5,10-15H2,1H3 RJBZCOQIWDMFST-UHFFFAOYSA-N 50018198 CHEMBL3289986 D(2) dopamine receptor Homo sapiens 46 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018198&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801018 242041879 CHEMBL3289986 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102471 O=S(=O)(NCCCCN1CCN(CC1)c1noc2ccccc12)c1cnc2ccccn12 InChI=1S/C22H26N6O3S/c29-32(30,21-17-23-20-9-3-5-12-28(20)21)24-10-4-6-11-26-13-15-27(16-14-26)22-18-7-1-2-8-19(18)31-25-22/h1-3,5,7-9,12,17,24H,4,6,10-11,13-16H2 KGQVGHYBVLHORN-UHFFFAOYSA-N 50018199 CHEMBL3289987 D(2) dopamine receptor Homo sapiens 100 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944189 242041880 CHEMBL3289987 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102472 O=S(=O)(NCCCN1CCN(CC1)c1noc2ccccc12)c1cccc2scnc12 InChI=1S/C21H23N5O3S2/c27-31(28,19-8-3-7-18-20(19)22-15-30-18)23-9-4-10-25-11-13-26(14-12-25)21-16-5-1-2-6-17(16)29-24-21/h1-3,5-8,15,23H,4,9-14H2 DIXICAHJOXMZSL-UHFFFAOYSA-N 50018200 CHEMBL3289988 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018200&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801116 242041881 CHEMBL3289988 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102473 O=S(=O)(NCCCCN1CCN(CC1)c1noc2ccccc12)c1cccc2scnc12 InChI=1S/C22H25N5O3S2/c28-32(29,20-9-5-8-19-21(20)23-16-31-19)24-10-3-4-11-26-12-14-27(15-13-26)22-17-6-1-2-7-18(17)30-25-22/h1-2,5-9,16,24H,3-4,10-15H2 KJUKPXSKIBFZAX-UHFFFAOYSA-N 50018201 CHEMBL3289989 D(2) dopamine receptor Homo sapiens 170 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018201&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801259 242041882 CHEMBL3289989 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102474 Cc1cccc(c1)S(=O)(=O)NCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C21H24FN3O3S/c1-15-3-2-4-18(13-15)29(26,27)23-9-12-25-10-7-16(8-11-25)21-19-6-5-17(22)14-20(19)28-24-21/h2-6,13-14,16,23H,7-12H2,1H3 KJWQBYGNNGUYBM-UHFFFAOYSA-N 50018202 CHEMBL3289990 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018202&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944764 242041883 CHEMBL3289990 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102475 Cc1cccc(c1)S(=O)(=O)NCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C22H26FN3O3S/c1-16-4-2-5-19(14-16)30(27,28)24-10-3-11-26-12-8-17(9-13-26)22-20-7-6-18(23)15-21(20)29-25-22/h2,4-7,14-15,17,24H,3,8-13H2,1H3 YFKQSGLMKFTUJN-UHFFFAOYSA-N 50018203 CHEMBL3289991 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018203&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56933434 242041884 CHEMBL3289991 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102476 Cc1cccc(c1)S(=O)(=O)NCCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H28FN3O3S/c1-17-5-4-6-20(15-17)31(28,29)25-11-2-3-12-27-13-9-18(10-14-27)23-21-8-7-19(24)16-22(21)30-26-23/h4-8,15-16,18,25H,2-3,9-14H2,1H3 BPVLKJSAFIGBKX-UHFFFAOYSA-N 50018204 CHEMBL3289992 D(2) dopamine receptor Homo sapiens 17 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018204&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944667 242041885 CHEMBL3289992 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102477 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C21H22Cl2FN3O3S/c22-18-5-3-16(13-19(18)23)31(28,29)25-8-1-9-27-10-6-14(7-11-27)21-17-4-2-15(24)12-20(17)30-26-21/h2-5,12-14,25H,1,6-11H2 WASWXYVTAUBCDE-UHFFFAOYSA-N 50018206 CHEMBL3289993 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018206&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801346 103929366 CHEMBL3289993 ZINC03789160 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102479 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C22H24Cl2FN3O3S/c23-19-6-4-17(14-20(19)24)32(29,30)26-9-1-2-10-28-11-7-15(8-12-28)22-18-5-3-16(25)13-21(18)31-27-22/h3-6,13-15,26H,1-2,7-12H2 BOERTKKBWLOLLH-UHFFFAOYSA-N 50018207 CHEMBL3289994 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018207&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944190 103929367 CHEMBL3289994 ZINC29241271 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102481 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2ccc(F)c(Cl)c2)CC1 InChI=1S/C21H22ClF2N3O3S/c22-18-13-16(3-5-19(18)24)31(28,29)25-8-1-9-27-10-6-14(7-11-27)21-17-4-2-15(23)12-20(17)30-26-21/h2-5,12-14,25H,1,6-11H2 FQRIRCXYLMTNDU-UHFFFAOYSA-N 50018208 CHEMBL3289995 D(2) dopamine receptor Homo sapiens 3.7 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018208&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801234 103929368 CHEMBL3289995 ZINC29308299 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102482 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2ccc(F)c(Cl)c2)CC1 InChI=1S/C22H24ClF2N3O3S/c23-19-14-17(4-6-20(19)25)32(29,30)26-9-1-2-10-28-11-7-15(8-12-28)22-18-5-3-16(24)13-21(18)31-27-22/h3-6,13-15,26H,1-2,7-12H2 DCVQHBNYAZYIKB-UHFFFAOYSA-N 50018209 CHEMBL3289996 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018209&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944191 103929369 CHEMBL3289996 ZINC29307328 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102483 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1 InChI=1S/C22H23F4N3O4S/c23-16-2-7-19-20(14-16)33-28-21(19)15-8-12-29(13-9-15)11-1-10-27-34(30,31)18-5-3-17(4-6-18)32-22(24,25)26/h2-7,14-15,27H,1,8-13H2 XRUQWQMSCMPGRN-UHFFFAOYSA-N 50018210 CHEMBL3289997 D(2) dopamine receptor Homo sapiens 33 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018210&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801028 103929370 CHEMBL3289997 ZINC11688252 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102486 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1 InChI=1S/C23H25F4N3O4S/c24-17-3-8-20-21(15-17)34-29-22(20)16-9-13-30(14-10-16)12-2-1-11-28-35(31,32)19-6-4-18(5-7-19)33-23(25,26)27/h3-8,15-16,28H,1-2,9-14H2 KQKAKONSXJYMCD-UHFFFAOYSA-N 50018215 CHEMBL3289998 D(2) dopamine receptor Homo sapiens 64 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018215&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944287 103929375 CHEMBL3289998 ZINC11688255 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102488 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2cccs2)CC1 InChI=1S/C19H22FN3O3S2/c20-15-4-5-16-17(13-15)26-22-19(16)14-6-10-23(11-7-14)9-2-8-21-28(24,25)18-3-1-12-27-18/h1,3-5,12-14,21H,2,6-11H2 FKKQLJVJIIRDRI-UHFFFAOYSA-N 50018221 CHEMBL3289999 D(2) dopamine receptor Homo sapiens 8.7 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801271 242041886 CHEMBL3289999 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102490 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cccs2)CC1 InChI=1S/C20H24FN3O3S2/c21-16-5-6-17-18(14-16)27-23-20(17)15-7-11-24(12-8-15)10-2-1-9-22-29(25,26)19-4-3-13-28-19/h3-6,13-15,22H,1-2,7-12H2 BDBDYFWUCQEXEB-UHFFFAOYSA-N 50018222 CHEMBL3290000 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66800910 242041887 CHEMBL3290000 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102491 Fc1ccc2c(noc2c1)C1CCN(CCNS(=O)(=O)c2cccc3ccccc23)CC1 InChI=1S/C24H24FN3O3S/c25-19-8-9-21-22(16-19)31-27-24(21)18-10-13-28(14-11-18)15-12-26-32(29,30)23-7-3-5-17-4-1-2-6-20(17)23/h1-9,16,18,26H,10-15H2 ZHUCAIBXMOFDCR-UHFFFAOYSA-N 50018223 CHEMBL3290001 D(2) dopamine receptor Homo sapiens 9.1 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018223&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944859 242041888 CHEMBL3290001 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102493 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2cccc3ccccc23)CC1 InChI=1S/C25H26FN3O3S/c26-20-9-10-22-23(17-20)32-28-25(22)19-11-15-29(16-12-19)14-4-13-27-33(30,31)24-8-3-6-18-5-1-2-7-21(18)24/h1-3,5-10,17,19,27H,4,11-16H2 MUGRBHXUBJDHNE-UHFFFAOYSA-N 50018224 CHEMBL3290002 D(2) dopamine receptor Homo sapiens 4.0 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018224&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801167 242041889 CHEMBL3290002 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102533 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cccc3ccccc23)CC1 InChI=1S/C26H28FN3O3S/c27-21-10-11-23-24(18-21)33-29-26(23)20-12-16-30(17-13-20)15-4-3-14-28-34(31,32)25-9-5-7-19-6-1-2-8-22(19)25/h1-2,5-11,18,20,28H,3-4,12-17H2 NLQDMIUSBFMXRV-UHFFFAOYSA-N 50018231 CHEMBL3290003 D(2) dopamine receptor Homo sapiens 3.0 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018231&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944665 103929387 CHEMBL3290003 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102534 Fc1ccc2c(noc2c1)C1CCN(CCNS(=O)(=O)c2ccc3ccccc3c2)CC1 InChI=1S/C24H24FN3O3S/c25-20-6-8-22-23(16-20)31-27-24(22)18-9-12-28(13-10-18)14-11-26-32(29,30)21-7-5-17-3-1-2-4-19(17)15-21/h1-8,15-16,18,26H,9-14H2 UBEFEBGEUSHFSH-UHFFFAOYSA-N 50018239 CHEMBL3290004 D(2) dopamine receptor Homo sapiens 5.2 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018239&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944763 103929395 CHEMBL3290004 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102535 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 InChI=1S/C25H26FN3O3S/c26-21-7-9-23-24(17-21)32-28-25(23)19-10-14-29(15-11-19)13-3-12-27-33(30,31)22-8-6-18-4-1-2-5-20(18)16-22/h1-2,4-9,16-17,19,27H,3,10-15H2 MCYLXTMEEBXVDF-UHFFFAOYSA-N 50018240 CHEMBL3290005 D(2) dopamine receptor Homo sapiens 1.000000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944668 103929396 CHEMBL3290005 ZINC36272602 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102536 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 InChI=1S/C26H28FN3O3S/c27-22-8-10-24-25(18-22)33-29-26(24)20-11-15-30(16-12-20)14-4-3-13-28-34(31,32)23-9-7-19-5-1-2-6-21(19)17-23/h1-2,5-10,17-18,20,28H,3-4,11-16H2 LSCFXOJSPYZWQQ-UHFFFAOYSA-N 50018241 CHEMBL3290006 D(2) dopamine receptor Homo sapiens 1.1 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944666 103929397 CHEMBL3290006 ZINC36272584 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102537 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1 InChI=1S/C25H25ClFN3O3S/c26-20-4-2-19-15-22(6-3-18(19)14-20)34(31,32)28-10-1-11-30-12-8-17(9-13-30)25-23-7-5-21(27)16-24(23)33-29-25/h2-7,14-17,28H,1,8-13H2 MAKSMZIXXYIHFQ-UHFFFAOYSA-N 50018242 CHEMBL3290007 D(2) dopamine receptor Homo sapiens 23 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018242&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801120 103929398 CHEMBL3290007 ZINC36272546 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102538 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1 InChI=1S/C26H27ClFN3O3S/c27-21-5-3-20-16-23(7-4-19(20)15-21)35(32,33)29-11-1-2-12-31-13-9-18(10-14-31)26-24-8-6-22(28)17-25(24)34-30-26/h3-8,15-18,29H,1-2,9-14H2 LMPJCXOOACXKHV-UHFFFAOYSA-N 50018243 CHEMBL3290008 D(2) dopamine receptor Homo sapiens 1.000000 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56943600 103929399 CHEMBL3290008 ZINC36272628 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102539 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2csc3ccccc23)CC1 InChI=1S/C23H24FN3O3S2/c24-17-6-7-18-20(14-17)30-26-23(18)16-8-12-27(13-9-16)11-3-10-25-32(28,29)22-15-31-21-5-2-1-4-19(21)22/h1-2,4-7,14-16,25H,3,8-13H2 NJJMNKOVGYIOBG-UHFFFAOYSA-N 50018244 CHEMBL3290009 D(2) dopamine receptor Homo sapiens 36 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018244&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801139 103929400 CHEMBL3290009 ZINC40662220 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102540 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2csc3ccccc23)CC1 InChI=1S/C24H26FN3O3S2/c25-18-7-8-19-21(15-18)31-27-24(19)17-9-13-28(14-10-17)12-4-3-11-26-33(29,30)23-16-32-22-6-2-1-5-20(22)23/h1-2,5-8,15-17,26H,3-4,9-14H2 CUNIDKSASOTBGS-UHFFFAOYSA-N 50018245 CHEMBL3290010 D(2) dopamine receptor Homo sapiens 22 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801225 103929401 CHEMBL3290010 ZINC36272709 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102541 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2cc3ccccc3s2)CC1 InChI=1S/C23H24FN3O3S2/c24-18-6-7-19-20(15-18)30-26-23(19)16-8-12-27(13-9-16)11-3-10-25-32(28,29)22-14-17-4-1-2-5-21(17)31-22/h1-2,4-7,14-16,25H,3,8-13H2 SNDXGGDDBIUIIR-UHFFFAOYSA-N 50018246 CHEMBL3290011 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801062 103929402 CHEMBL3290011 ZINC36272575 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102554 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cc3ccccc3s2)CC1 InChI=1S/C24H26FN3O3S2/c25-19-7-8-20-21(16-19)31-27-24(20)17-9-13-28(14-10-17)12-4-3-11-26-33(29,30)23-15-18-5-1-2-6-22(18)32-23/h1-2,5-8,15-17,26H,3-4,9-14H2 GXZWKZAOGQRNTL-UHFFFAOYSA-N 50018019 CHEMBL3290012 D(2) dopamine receptor Homo sapiens 2.0 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944383 103929195 CHEMBL3290012 ZINC28102656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101515 [O-][S+](CCCN1CCN(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C19H22ClFN2OS/c20-16-2-6-18(7-3-16)23-13-11-22(12-14-23)10-1-15-25(24)19-8-4-17(21)5-9-19/h2-9H,1,10-15H2 FIIJQHSUFMYWQS-UHFFFAOYSA-N 50017975 CHEMBL3289383 D(2) dopamine receptor Homo sapiens 635 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017975&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644067 242041867 CHEMBL3289383 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101517 Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1 InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2 ARWONURFSGKTJW-UHFFFAOYSA-N 50362853 CHEMBL1940408 D(2) dopamine receptor Homo sapiens 284 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57401819 136966915 CHEMBL1940408 ZINC73240518 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101518 Fc1ccc(SCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1 InChI=1S/C19H22ClFN2S/c20-16-2-6-18(7-3-16)23-13-11-22(12-14-23)10-1-15-24-19-8-4-17(21)5-9-19/h2-9H,1,10-15H2 QEVFANOTWOZMFN-UHFFFAOYSA-N 50362854 CHEMBL1940409 D(2) dopamine receptor Homo sapiens 211 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57401820 136966916 CHEMBL1940409 ZINC73239724 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101519 Fc1ccc(OCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1 InChI=1S/C19H22ClFN2O/c20-16-2-6-18(7-3-16)23-13-11-22(12-14-23)10-1-15-24-19-8-4-17(21)5-9-19/h2-9H,1,10-15H2 TYJIKVPYZAVEMZ-UHFFFAOYSA-N 50362856 CHEMBL1940411 D(2) dopamine receptor Homo sapiens 390 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57391307 136966918 CHEMBL1940411 ZINC73239729 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101520 Clc1ccc(cc1)N1CCN(CCCOc2ccccc2)CC1 InChI=1S/C19H23ClN2O/c20-17-7-9-18(10-8-17)22-14-12-21(13-15-22)11-4-16-23-19-5-2-1-3-6-19/h1-3,5-10H,4,11-16H2 DFNAAFSXZVGDBJ-UHFFFAOYSA-N 50362858 CHEMBL1940413 D(2) dopamine receptor Homo sapiens 447 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57396571 136966920 CHEMBL1940413 ZINC73220413 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101522 Fc1ccc(OCCCN2CCC(CC2)c2ccc(Cl)cc2)cc1 InChI=1S/C20H23ClFNO/c21-18-4-2-16(3-5-18)17-10-13-23(14-11-17)12-1-15-24-20-8-6-19(22)7-9-20/h2-9,17H,1,10-15H2 OPXIAQIQFMLKDK-UHFFFAOYSA-N 50362870 CHEMBL1940406 D(2) dopamine receptor Homo sapiens 41 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57398351 136966932 CHEMBL1940406 ZINC73239717 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101523 Fc1ccc2C(=O)C(CCN3CCN(CC3)c3ccc(Cl)cc3)Cc2c1 InChI=1S/C21H22ClFN2O/c22-17-1-4-19(5-2-17)25-11-9-24(10-12-25)8-7-15-13-16-14-18(23)3-6-20(16)21(15)26/h1-6,14-15H,7-13H2 JLUQWCZYPJKNMK-UHFFFAOYSA-N 50017966 CHEMBL3289642 D(2) dopamine receptor Homo sapiens 1543 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644058 242041858 CHEMBL3289642 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101525 Clc1ccc(cc1)N1CCN(CCC2Cc3ccccc3C2=O)CC1 InChI=1S/C21H23ClN2O/c22-18-5-7-19(8-6-18)24-13-11-23(12-14-24)10-9-17-15-16-3-1-2-4-20(16)21(17)25/h1-8,17H,9-15H2 CPFAMVVFLCOFSK-UHFFFAOYSA-N 50017967 CHEMBL3289643 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644059 242041859 CHEMBL3289643 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101526 Fc1ccc2CC(CCN3CCN(CC3)c3ccc(Cl)cc3)Cc2c1 InChI=1S/C21H24ClFN2/c22-19-2-5-21(6-3-19)25-11-9-24(10-12-25)8-7-16-13-17-1-4-20(23)15-18(17)14-16/h1-6,15-16H,7-14H2 XASUAOWUPBWGMW-UHFFFAOYSA-N 50017968 CHEMBL3289644 D(2) dopamine receptor Homo sapiens 1417 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017968&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644060 242041860 CHEMBL3289644 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101527 Fc1ccc(CCCCN2CCN(CC2)c2ccccn2)cc1 InChI=1S/C19H24FN3/c20-18-9-7-17(8-10-18)5-2-4-12-22-13-15-23(16-14-22)19-6-1-3-11-21-19/h1,3,6-11H,2,4-5,12-16H2 NSMCYUMPIGJKHV-UHFFFAOYSA-N 50362863 CHEMBL1940418 D(2) dopamine receptor Homo sapiens 124 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44209480 136966925 CHEMBL1940418 ZINC43211125 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101528 Fc1ccc(SCCCN2CCN(CC2)c2ccccn2)cc1 InChI=1S/C18H22FN3S/c19-16-5-7-17(8-6-16)23-15-3-10-21-11-13-22(14-12-21)18-4-1-2-9-20-18/h1-2,4-9H,3,10-15H2 IESJRUUOIHDONG-UHFFFAOYSA-N 50362864 CHEMBL1940419 D(2) dopamine receptor Homo sapiens 183 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57401706 136966926 CHEMBL1940419 ZINC73222863 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101529 Fc1ccc(OCCCN2CCN(CC2)c2ccccn2)cc1 InChI=1S/C18H22FN3O/c19-16-5-7-17(8-6-16)23-15-3-10-21-11-13-22(14-12-21)18-4-1-2-9-20-18/h1-2,4-9H,3,10-15H2 BPDDCCYSOYRMEC-UHFFFAOYSA-N 50362865 CHEMBL1940420 D(2) dopamine receptor Homo sapiens 186 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44209472 136966927 CHEMBL1940420 ZINC60992916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101530 FC(F)(F)c1ccc(OCCCN2CCN(CC2)c2ccccn2)cc1 InChI=1S/C19H22F3N3O/c20-19(21,22)16-5-7-17(8-6-16)26-15-3-10-24-11-13-25(14-12-24)18-4-1-2-9-23-18/h1-2,4-9H,3,10-15H2 APDUBUJHUYQKMX-UHFFFAOYSA-N 50017965 CHEMBL3289645 D(2) dopamine receptor Homo sapiens 1092 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644057 242041857 CHEMBL3289645 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102601 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1 InChI=1S/C23H23ClFN3O3S2/c24-17-3-2-16-12-22(32-21(16)13-17)33(29,30)26-8-1-9-28-10-6-15(7-11-28)23-19-5-4-18(25)14-20(19)31-27-23/h2-5,12-15,26H,1,6-11H2 XTENPQMXIHRLGV-UHFFFAOYSA-N 50018247 CHEMBL3290013 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801251 103929403 CHEMBL3290013 ZINC36113790 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102604 Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1 InChI=1S/C24H25ClFN3O3S2/c25-18-4-3-17-13-23(33-22(17)14-18)34(30,31)27-9-1-2-10-29-11-7-16(8-12-29)24-20-6-5-19(26)15-21(20)32-28-24/h3-6,13-16,27H,1-2,7-12H2 ZMIWRRKLVCCVBJ-UHFFFAOYSA-N 50018248 CHEMBL3290014 D(2) dopamine receptor Homo sapiens 1.2 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56944384 103929404 CHEMBL3290014 ZINC36272706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102614 Cc1c(sc2ccc(F)cc12)S(=O)(=O)NCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C24H25F2N3O3S2/c1-15-20-13-17(25)4-6-22(20)33-24(15)34(30,31)27-9-2-10-29-11-7-16(8-12-29)23-19-5-3-18(26)14-21(19)32-28-23/h3-6,13-14,16,27H,2,7-12H2,1H3 RAYWFVBTQQRRAT-UHFFFAOYSA-N 50018249 CHEMBL3290015 D(2) dopamine receptor Homo sapiens 8.0 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56943695 103929405 CHEMBL3290015 ZINC36272640 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102618 Cc1c(sc2ccc(F)cc12)S(=O)(=O)NCCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C25H27F2N3O3S2/c1-16-21-14-18(26)5-7-23(21)34-25(16)35(31,32)28-10-2-3-11-30-12-8-17(9-13-30)24-20-6-4-19(27)15-22(20)33-29-24/h4-7,14-15,17,28H,2-3,8-13H2,1H3 GCGNPPCFOWHEEJ-UHFFFAOYSA-N 50018250 CHEMBL3290016 D(2) dopamine receptor Homo sapiens 1.9 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801551 103929406 CHEMBL3290016 ZINC36272557 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102622 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)NCCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C25H27ClFN3O3S2/c1-16-21-14-18(26)4-7-23(21)34-25(16)35(31,32)28-10-2-3-11-30-12-8-17(9-13-30)24-20-6-5-19(27)15-22(20)33-29-24/h4-7,14-15,17,28H,2-3,8-13H2,1H3 QVJKMHVHKSTLSO-UHFFFAOYSA-N 50018251 CHEMBL3290017 D(2) dopamine receptor Homo sapiens 1.5 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801210 103929407 CHEMBL3290017 ZINC40786220 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102623 Fc1ccc2c(noc2c1)C1CCN(CCCNS(=O)(=O)c2cnc3ccccn23)CC1 InChI=1S/C22H24FN5O3S/c23-17-5-6-18-19(14-17)31-26-22(18)16-7-12-27(13-8-16)10-3-9-25-32(29,30)21-15-24-20-4-1-2-11-28(20)21/h1-2,4-6,11,14-16,25H,3,7-10,12-13H2 OOTYIPXZQVEHNY-UHFFFAOYSA-N 50018252 CHEMBL3290018 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66801186 103929408 CHEMBL3290018 ZINC36272728 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50102625 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Homo sapiens <10.0 ChEMBL 10.1021/jm401895u 10.7270/Q2N29ZHX 24805037 Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P Adamed Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101588 Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3o2)CC1 InChI=1S/C20H22ClN3O/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2 ZLUCWPDQINEIOK-UHFFFAOYSA-N 50017973 CHEMBL3286429 D(2) dopamine receptor Homo sapiens 3962 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017973&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644065 242041865 CHEMBL3286429 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101589 Clc1ccc(cc1)N1CCN(CCCc2cc3ccccc3o2)CC1 InChI=1S/C21H23ClN2O/c22-18-7-9-19(10-8-18)24-14-12-23(13-15-24)11-3-5-20-16-17-4-1-2-6-21(17)25-20/h1-2,4,6-10,16H,3,5,11-15H2 BPHVHUHFXREQBY-UHFFFAOYSA-N 50017974 CHEMBL3289653 D(2) dopamine receptor Homo sapiens 1979 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017974&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644066 242041866 CHEMBL3289653 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101590 Clc1ccc(cc1)N1CCCN(CCCc2cc3ccccc3o2)CC1 InChI=1S/C22H25ClN2O/c23-19-8-10-20(11-9-19)25-14-4-13-24(15-16-25)12-3-6-21-17-18-5-1-2-7-22(18)26-21/h1-2,5,7-11,17H,3-4,6,12-16H2 MKNOKGDTUIIQRL-UHFFFAOYSA-N 50017988 CHEMBL3289655 D(2) dopamine receptor Homo sapiens 2507 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017988&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644071 103929164 CHEMBL3289655 ZINC96179006 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101591 C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1 InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2 LOWWSZHAZVDMAY-UHFFFAOYSA-N 50384954 CHEMBL2037521 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165418 160864037 CHEMBL2037521 ZINC84670852 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101592 Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1 InChI=1S/C18H19ClN4/c19-16-4-6-17(7-5-16)22-11-9-21(10-12-22)14-15-13-20-23-8-2-1-3-18(15)23/h1-8,13H,9-12,14H2 XVPRVMIFXXOEFR-UHFFFAOYSA-N 50073805 3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine::3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::4-(4-Chloro-phenyl)-1-pyrazolo[1,5-a]pyridin-3-ylmethyl-piperazin-1-ium::CHEMBL7927::FAUC 113 D(2) dopamine receptor Homo sapiens 3200 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10404144 103967091 CHEMBL7927 ZINC13438692 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50101593 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OGJGQVFWEPNYSB-UHFFFAOYSA-N 85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853 D(2) dopamine receptor Homo sapiens 960 ChEMBL 10.1016/j.bmc.2014.04.026 10.7270/Q25140RW 24800940 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L74 6IQL 5311200 136351193 CHEMBL555670CHEMBL267014 3303 ZINC25760037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103828 Cc1ccc(OCCNCCCOc2ccc(F)cc2)cc1 InChI=1S/C18H22FNO2/c1-15-3-7-17(8-4-15)22-14-12-20-11-2-13-21-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3 ORHJUTONXWXCOS-UHFFFAOYSA-N 50061325 CHEMBL131357::[3-(4-Fluoro-phenoxy)-propyl]-(2-p-tolyloxy-ethyl)-amine D(2) dopamine receptor Homo sapiens 391.0 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10447709 103956887 CHEMBL131357 ZINC13766801 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103830 Cc1ccc(OCCNCCCOc2cccc(C)c2)cc1 InChI=1S/C19H25NO2/c1-16-7-9-18(10-8-16)22-14-12-20-11-4-13-21-19-6-3-5-17(2)15-19/h3,5-10,15,20H,4,11-14H2,1-2H3 RUVQMQUPSVELIK-UHFFFAOYSA-N 50061327 (2-p-Tolyloxy-ethyl)-(3-m-tolyloxy-propyl)-amine::CHEMBL435598 D(2) dopamine receptor Homo sapiens 292 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10494394 103956889 CHEMBL435598 ZINC13766795 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103832 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 91 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103842 Cc1ccccc1OCCNCCCOc1ccccc1 InChI=1S/C18H23NO2/c1-16-8-5-6-11-18(16)21-15-13-19-12-7-14-20-17-9-3-2-4-10-17/h2-6,8-11,19H,7,12-15H2,1H3 ZOQYTWXGFAVKMT-UHFFFAOYSA-N 50061335 (3-Phenoxy-propyl)-(2-o-tolyloxy-ethyl)-amine::CHEMBL128313 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10636896 103956897 CHEMBL128313 ZINC13766772 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103844 Cc1ccc(OCCNCCCOc2ccccc2)cc1Cl InChI=1S/C18H22ClNO2/c1-15-8-9-17(14-18(15)19)22-13-11-20-10-5-12-21-16-6-3-2-4-7-16/h2-4,6-9,14,20H,5,10-13H2,1H3 FLJUYWJINNZFMZ-UHFFFAOYSA-N 50061334 CHEMBL131997::[2-(3-Chloro-4-methyl-phenoxy)-ethyl]-(3-phenoxy-propyl)-amine D(2) dopamine receptor Homo sapiens 299 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10450892 103956896 CHEMBL131997 ZINC01545792 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103845 Oc1ccc(OCCNCCCOc2ccccc2)cc1 InChI=1S/C17H21NO3/c19-15-7-9-17(10-8-15)21-14-12-18-11-4-13-20-16-5-2-1-3-6-16/h1-3,5-10,18-19H,4,11-14H2 KNRRIHFTWQMRNB-UHFFFAOYSA-N 50061336 4-[2-(3-Phenoxy-propylamino)-ethoxy]-phenol::CHEMBL22892 D(2) dopamine receptor Homo sapiens 556 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684706 103956898 CHEMBL22892 ZINC13766780 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103848 Clc1ccc(SCCNCCCOc2ccccc2)cc1 InChI=1S/C17H20ClNOS/c18-15-7-9-17(10-8-15)21-14-12-19-11-4-13-20-16-5-2-1-3-6-16/h1-3,5-10,19H,4,11-14H2 SDAOADFGOQZYMJ-UHFFFAOYSA-N 50061328 CHEMBL130347::[2-(4-Chloro-phenylsulfanyl)-ethyl]-(3-phenoxy-propyl)-amine D(2) dopamine receptor Homo sapiens 352 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10782049 103956890 CHEMBL130347 ZINC13766807 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103850 Cc1ccc(CCCNCCCOc2ccccc2)cc1 InChI=1S/C19H25NO/c1-17-10-12-18(13-11-17)7-5-14-20-15-6-16-21-19-8-3-2-4-9-19/h2-4,8-13,20H,5-7,14-16H2,1H3 ALJVVUIFWXGXTR-UHFFFAOYSA-N 50061331 (3-Phenoxy-propyl)-(3-p-tolyl-propyl)-amine::CHEMBL334989 D(2) dopamine receptor Homo sapiens 364 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948965 103956893 CHEMBL334989 ZINC13766811 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103852 Clc1ccc(OCCNCCCOc2ccccc2)cc1 InChI=1S/C17H20ClNO2/c18-15-7-9-17(10-8-15)21-14-12-19-11-4-13-20-16-5-2-1-3-6-16/h1-3,5-10,19H,4,11-14H2 ZHDNXHKBRYCOSE-UHFFFAOYSA-N 50061339 CHEMBL132884::[2-(4-Chloro-phenoxy)-ethyl]-(3-phenoxy-propyl)-amine D(2) dopamine receptor Homo sapiens 228.0 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10315310 103956901 CHEMBL132884 ZINC01545791 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103853 Cc1ccc(OCCCNCCOc2ccccc2)cc1 InChI=1S/C18H23NO2/c1-16-8-10-18(11-9-16)20-14-5-12-19-13-15-21-17-6-3-2-4-7-17/h2-4,6-11,19H,5,12-15H2,1H3 YEUKYYRBGVTVHI-UHFFFAOYSA-N 50061337 (2-Phenoxy-ethyl)-(3-p-tolyloxy-propyl)-amine::CHEMBL131299 D(2) dopamine receptor Homo sapiens 64 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10589218 103956899 CHEMBL131299 ZINC13766792 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103856 Cc1ccc(OCCNCCCOc2ccccc2)cc1 InChI=1S/C18H23NO2/c1-16-8-10-18(11-9-16)21-15-13-19-12-5-14-20-17-6-3-2-4-7-17/h2-4,6-11,19H,5,12-15H2,1H3 MJWITHOHGGKZJZ-UHFFFAOYSA-N 50061332 (3-Phenoxy-propyl)-(2-p-tolyloxy-ethyl)-amine::CHEMBL128647 D(2) dopamine receptor Homo sapiens 268 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10708280 103956894 CHEMBL128647 ZINC01545790 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103860 Clc1ccc(OCCNCCCSc2ccccc2)cc1 InChI=1S/C17H20ClNOS/c18-15-7-9-16(10-8-15)20-13-12-19-11-4-14-21-17-5-2-1-3-6-17/h1-3,5-10,19H,4,11-14H2 HGOOBSLSWOJAPR-UHFFFAOYSA-N 50061338 CHEMBL337627::[2-(4-Chloro-phenoxy)-ethyl]-(3-phenylsulfanyl-propyl)-amine D(2) dopamine receptor Homo sapiens 227 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10615787 103956900 CHEMBL337627 ZINC13766803 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103862 Fc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1 InChI=1S/C17H19ClFNO2/c18-14-2-6-16(7-3-14)22-13-11-20-10-1-12-21-17-8-4-15(19)5-9-17/h2-9,20H,1,10-13H2 CUIKAPOUIHQKER-UHFFFAOYSA-N 50061330 CHEMBL129757::[2-(4-Chloro-phenoxy)-ethyl]-[3-(4-fluoro-phenoxy)-propyl]-amine D(2) dopamine receptor Homo sapiens 245 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10734727 103956892 CHEMBL129757 ZINC13766790 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103864 Cc1ccc(OCCNCCCOc2ccccc2C)cc1 InChI=1S/C19H25NO2/c1-16-8-10-18(11-9-16)21-15-13-20-12-5-14-22-19-7-4-3-6-17(19)2/h3-4,6-11,20H,5,12-15H2,1-2H3 DGFGHVHKQCWUJA-UHFFFAOYSA-N 50061324 (2-p-Tolyloxy-ethyl)-(3-o-tolyloxy-propyl)-amine::CHEMBL334545 D(2) dopamine receptor Homo sapiens 296 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10732925 103956886 CHEMBL334545 ZINC13766794 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103869 Cc1ccc(OCCNCCCOc2ccccc2)cc1C InChI=1S/C19H25NO2/c1-16-9-10-19(15-17(16)2)22-14-12-20-11-6-13-21-18-7-4-3-5-8-18/h3-5,7-10,15,20H,6,11-14H2,1-2H3 KXVOVPCKFATOKG-UHFFFAOYSA-N 50061345 CHEMBL129927::[2-(3,4-Dimethyl-phenoxy)-ethyl]-(3-phenoxy-propyl)-amine D(2) dopamine receptor Homo sapiens 143 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780510 103956907 CHEMBL129927 ZINC13766784 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103870 C(CNCCOc1ccccc1)COc1ccccc1 InChI=1S/C17H21NO2/c1-3-8-16(9-4-1)19-14-7-12-18-13-15-20-17-10-5-2-6-11-17/h1-6,8-11,18H,7,12-15H2 IHBJWORPKYVGRO-UHFFFAOYSA-N 50061346 (2-Phenoxy-ethyl)-(3-phenoxy-propyl)-amine::CHEMBL128524 D(2) dopamine receptor Homo sapiens 251 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10588194 103956908 CHEMBL128524 ZINC13766768 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103882 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.6 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103884 C(CNCCCc1ccccc1)COc1ccccc1 InChI=1S/C18H23NO/c1-3-9-17(10-4-1)11-7-14-19-15-8-16-20-18-12-5-2-6-13-18/h1-6,9-10,12-13,19H,7-8,11,14-16H2 AHYUXDAZVIOABZ-UHFFFAOYSA-N 50061333 (3-Phenoxy-propyl)-(3-phenyl-propyl)-amine::CHEMBL129931 D(2) dopamine receptor Homo sapiens 519.0 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948461 103956895 CHEMBL129931 ZINC12355992 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103887 Clc1cccc(OCCNCCCOc2ccccc2)c1 InChI=1S/C17H20ClNO2/c18-15-6-4-9-17(14-15)21-13-11-19-10-5-12-20-16-7-2-1-3-8-16/h1-4,6-9,14,19H,5,10-13H2 BJMUZOAJZPCYCW-UHFFFAOYSA-N 50061349 CHEMBL129534::[2-(3-Chloro-phenoxy)-ethyl]-(3-phenoxy-propyl)-amine D(2) dopamine receptor Homo sapiens 22 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10733406 103956911 CHEMBL129534 ZINC13766774 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103888 Cc1ccc(SCCNCCCOc2ccccc2)cc1 InChI=1S/C18H23NOS/c1-16-8-10-18(11-9-16)21-15-13-19-12-5-14-20-17-6-3-2-4-7-17/h2-4,6-11,19H,5,12-15H2,1H3 FGWDTOKLDRSCNA-UHFFFAOYSA-N 50061342 (3-Phenoxy-propyl)-(2-p-tolylsulfanyl-ethyl)-amine::CHEMBL128281 D(2) dopamine receptor Homo sapiens 222 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10542345 103956904 CHEMBL128281 ZINC13766809 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103889 Cc1ccc(OCCCNCCOc2ccc(C)cc2)cc1 InChI=1S/C19H25NO2/c1-16-4-8-18(9-5-16)21-14-3-12-20-13-15-22-19-10-6-17(2)7-11-19/h4-11,20H,3,12-15H2,1-2H3 AXXXFCGETBIMKI-UHFFFAOYSA-N 50061344 (2-p-Tolyloxy-ethyl)-(3-p-tolyloxy-propyl)-amine::CHEMBL130370 D(2) dopamine receptor Homo sapiens 277 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10590285 103956906 CHEMBL130370 ZINC13766797 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103890 Cc1ccc(OCCNCCCOc2ccc(Br)cc2)cc1 InChI=1S/C18H22BrNO2/c1-15-3-7-17(8-4-15)22-14-12-20-11-2-13-21-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3 VOLSMORQSJTKPA-UHFFFAOYSA-N 50061347 CHEMBL341225::[3-(4-Bromo-phenoxy)-propyl]-(2-p-tolyloxy-ethyl)-amine D(2) dopamine receptor Homo sapiens 5730 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10498972 103956909 CHEMBL341225 ZINC13766799 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103891 Cc1ccc(OCCNCCCSc2ccccc2)cc1 InChI=1S/C18H23NOS/c1-16-8-10-17(11-9-16)20-14-13-19-12-5-15-21-18-6-3-2-4-7-18/h2-4,6-11,19H,5,12-15H2,1H3 AZGSWFQAJQTIDP-UHFFFAOYSA-N 50061329 (3-Phenylsulfanyl-propyl)-(2-p-tolyloxy-ethyl)-amine::CHEMBL130402 D(2) dopamine receptor Homo sapiens 118 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10638052 103956891 CHEMBL130402 ZINC13766805 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50103892 Cc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1 InChI=1S/C18H22ClNO2/c1-15-3-7-17(8-4-15)21-13-2-11-20-12-14-22-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3 TXYPYDVBBSFEGP-UHFFFAOYSA-N 50061326 CHEMBL131484::[2-(4-Chloro-phenoxy)-ethyl]-(3-p-tolyloxy-propyl)-amine D(2) dopamine receptor Homo sapiens 1320 ChEMBL 10.1021/jm970422s 10.7270/Q22J69Z9 9406594 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10758004 103956888 CHEMBL131484 ZINC13766786 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50108248 OC(CCNC(=O)c1cc2ccccc2[nH]1)CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H26Cl2N4O2/c24-18-5-3-7-21(22(18)25)29-12-10-28(11-13-29)15-17(30)8-9-26-23(31)20-14-16-4-1-2-6-19(16)27-20/h1-7,14,17,27,30H,8-13,15H2,(H,26,31) NABHHUMHJIHHIX-UHFFFAOYSA-N 123850 US8748608, 34::US8748608, 34 Enantiomer A::US8748608, 34 Enantiomer B D(2) dopamine receptor Homo sapiens 750 ChEMBL 10.1021/ml500006v 10.7270/Q2QC053B 24944737 Kumar, V; Banala, AK; Garcia, EG; Cao, J; Keck, TM; Bonifazi, A; Deschamps, JR; Newman, AH National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25141534 225150256 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50108251 O[C@H](CCNC(=O)c1cc2ccccc2[nH]1)CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H26Cl2N4O2/c24-18-5-3-7-21(22(18)25)29-12-10-28(11-13-29)15-17(30)8-9-26-23(31)20-14-16-4-1-2-6-19(16)27-20/h1-7,14,17,27,30H,8-13,15H2,(H,26,31)/t17-/m1/s1 NABHHUMHJIHHIX-QGZVFWFLSA-N 50342720 (R)-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydroxybutyl)-1H-indole-2-carboxamide::CHEMBL1627306 D(2) dopamine receptor Homo sapiens 300 ChEMBL 10.1021/ml500006v 10.7270/Q2QC053B 24944737 Kumar, V; Banala, AK; Garcia, EG; Cao, J; Keck, TM; Bonifazi, A; Deschamps, JR; Newman, AH National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42626318 131345656 CHEMBL1627306 ZINC66120262 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50108252 O[C@@H](CCNC(=O)c1cc2ccccc2[nH]1)CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H26Cl2N4O2/c24-18-5-3-7-21(22(18)25)29-12-10-28(11-13-29)15-17(30)8-9-26-23(31)20-14-16-4-1-2-6-19(16)27-20/h1-7,14,17,27,30H,8-13,15H2,(H,26,31)/t17-/m0/s1 NABHHUMHJIHHIX-KRWDZBQOSA-N 50378015 CHEMBL1627307 D(2) dopamine receptor Homo sapiens 790 ChEMBL 10.1021/ml500006v 10.7270/Q2QC053B 24944737 Kumar, V; Banala, AK; Garcia, EG; Cao, J; Keck, TM; Bonifazi, A; Deschamps, JR; Newman, AH National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42626240 160857098 CHEMBL1627307 ZINC66120280 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50108254 FC(CCNC(=O)c1cc2ccccc2o1)CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H24Cl2FN3O2/c24-18-5-3-6-19(22(18)25)29-12-10-28(11-13-29)15-17(26)8-9-27-23(30)21-14-16-4-1-2-7-20(16)31-21/h1-7,14,17H,8-13,15H2,(H,27,30) LRBUVURCWWAQQT-UHFFFAOYSA-N 50343785 CHEMBL1774386::N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluorobutyl)-benzofuran-2-carboxamide D(2) dopamine receptor Homo sapiens 960 ChEMBL 10.1021/ml500006v 10.7270/Q2QC053B 24944737 Kumar, V; Banala, AK; Garcia, EG; Cao, J; Keck, TM; Bonifazi, A; Deschamps, JR; Newman, AH National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53248209 131346721 CHEMBL1774386 ZINC71316468 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50108255 F[C@H](CCNC(=O)c1cc2ccccc2o1)CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H24Cl2FN3O2/c24-18-5-3-6-19(22(18)25)29-12-10-28(11-13-29)15-17(26)8-9-27-23(30)21-14-16-4-1-2-7-20(16)31-21/h1-7,14,17H,8-13,15H2,(H,27,30)/t17-/m1/s1 LRBUVURCWWAQQT-QGZVFWFLSA-N 50020916 CHEMBL3287279 D(2) dopamine receptor Homo sapiens 800 ChEMBL 10.1021/ml500006v 10.7270/Q2QC053B 24944737 Kumar, V; Banala, AK; Garcia, EG; Cao, J; Keck, TM; Bonifazi, A; Deschamps, JR; Newman, AH National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020916&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644928 103931631 CHEMBL3287279 ZINC13565475 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50108256 F[C@@H](CCNC(=O)c1cc2ccccc2o1)CN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H24Cl2FN3O2/c24-18-5-3-6-19(22(18)25)29-12-10-28(11-13-29)15-17(26)8-9-27-23(30)21-14-16-4-1-2-7-20(16)31-21/h1-7,14,17H,8-13,15H2,(H,27,30)/t17-/m0/s1 LRBUVURCWWAQQT-KRWDZBQOSA-N 50020917 CHEMBL3287280 D(2) dopamine receptor Homo sapiens 2500 ChEMBL 10.1021/ml500006v 10.7270/Q2QC053B 24944737 Kumar, V; Banala, AK; Garcia, EG; Cao, J; Keck, TM; Bonifazi, A; Deschamps, JR; Newman, AH National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644929 103931632 CHEMBL3287280 ZINC28008466 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50108257 FCC(CCNC(=O)c1cc2ccccc2o1)N1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H24Cl2FN3O2/c24-18-5-3-6-19(22(18)25)29-12-10-28(11-13-29)17(15-26)8-9-27-23(30)21-14-16-4-1-2-7-20(16)31-21/h1-7,14,17H,8-13,15H2,(H,27,30) QBRAQPXCJIBXIU-UHFFFAOYSA-N 50020918 CHEMBL3287281 D(2) dopamine receptor Homo sapiens 7400 ChEMBL 10.1021/ml500006v 10.7270/Q2QC053B 24944737 Kumar, V; Banala, AK; Garcia, EG; Cao, J; Keck, TM; Bonifazi, A; Deschamps, JR; Newman, AH National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90644930 103931633 CHEMBL3287281 ZINC28011432 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50106537 CCc1ccccc1NC(=O)N1C[C@@H](C)Oc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1 InChI=1S/C32H36N2O4/c1-3-23-6-4-5-7-28(23)33-32(37)34-20-21(2)38-30-19-27(16-17-29(30)34)26-14-12-25(13-15-26)24-10-8-22(9-11-24)18-31(35)36/h4-7,12-17,19,21-22,24H,3,8-11,18,20H2,1-2H3,(H,33,37)(H,35,36)/t21-,22-,24-/m1/s1 PUQLADUSPHHAJY-CQOQZXRMSA-N 50020044 CHEMBL3287898 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1021/ml400527n 10.7270/Q2KS6T3C 24900877 Zhou, G; Zorn, N; Ting, P; Aslanian, R; Lin, M; Cook, J; Lachowicz, J; Lin, A; Smith, M; Hwa, J; van Heek, M; Walker, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86277844 103930967 CHEMBL3287898 ZINC28232392 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107815 C(CN1CCC(=CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C23H30N4/c1-2-5-20(6-3-1)21-12-17-27(18-13-21)16-11-19-7-9-22(10-8-19)26-23-24-14-4-15-25-23/h1-6,12,14-15,19,22H,7-11,13,16-18H2,(H,24,25,26)/t19-,22- BDHDIEVXYUODTG-XYWHTSSQSA-N 50063276 CHEMBL164604::{4-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 4.7 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10642428 103958607 CHEMBL164604 ZINC13778689 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107819 Fc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 InChI=1S/C22H30FN5/c23-19-4-8-21(9-5-19)28-16-14-27(15-17-28)13-10-18-2-6-20(7-3-18)26-22-24-11-1-12-25-22/h1,4-5,8-9,11-12,18,20H,2-3,6-7,10,13-17H2,(H,24,25,26)/t18-,20- FANDJZBJYJYKGY-KESTWPANSA-N 50063277 (4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine::CHEMBL349034 D(2) dopamine receptor Homo sapiens 8.5 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10738750 103958608 CHEMBL349034 ZINC13778704 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107823 C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C21H30N6/c1-2-10-22-20(4-1)27-16-14-26(15-17-27)13-9-18-5-7-19(8-6-18)25-21-23-11-3-12-24-21/h1-4,10-12,18-19H,5-9,13-17H2,(H,23,24,25)/t18-,19- YKCHNWKXANLFGS-WGSAOQKQSA-N 50063280 CHEMBL355371::{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522950 103958611 CHEMBL355371 ZINC13778706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107825 FC(F)(F)c1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 InChI=1S/C23H30F3N5/c24-23(25,26)19-3-1-4-21(17-19)31-15-13-30(14-16-31)12-9-18-5-7-20(8-6-18)29-22-27-10-2-11-28-22/h1-4,10-11,17-18,20H,5-9,12-16H2,(H,27,28,29)/t18-,20- CHELUMIQBPPRGN-KESTWPANSA-N 50063285 CHEMBL165056::Pyrimidin-2-yl-(4-{2-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amine D(2) dopamine receptor Homo sapiens 6 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10765237 103958616 CHEMBL165056 ZINC13778702 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107833 C(C[C@H]1CC[C@@H](CC1)Nc1ncccn1)CN1CCN(CC1)c1ccccc1 InChI=1S/C23H33N5/c1-2-7-22(8-3-1)28-18-16-27(17-19-28)15-4-6-20-9-11-21(12-10-20)26-23-24-13-5-14-25-23/h1-3,5,7-8,13-14,20-21H,4,6,9-12,15-19H2,(H,24,25,26)/t20-,21- GXOXNWXNCBKFTM-MEMLXQNLSA-N 50063289 CHEMBL165140::{4-[3-(4-Phenyl-piperazin-1-yl)-propyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 7.4 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10499950 103958620 CHEMBL165140 ZINC13778686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107836 C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccccc12 InChI=1S/C26H33N5/c1-2-6-23(7-3-1)31-18-16-30(17-19-31)15-14-21-10-12-22(13-11-21)29-26-24-8-4-5-9-25(24)27-20-28-26/h1-9,20-22H,10-19H2,(H,27,28,29)/t21-,22- IVCDUDHUOFADMA-HZCBDIJESA-N 50063292 CHEMBL349426::{4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-quinazolin-4-yl-amine D(2) dopamine receptor Homo sapiens 3.2 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063292&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740593 103958623 CHEMBL349426 ZINC13778682 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107840 C(CN1CCN(CC1)c1ncccn1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C20H29N7/c1-8-21-19(22-9-1)25-18-5-3-17(4-6-18)7-12-26-13-15-27(16-14-26)20-23-10-2-11-24-20/h1-2,8-11,17-18H,3-7,12-16H2,(H,21,22,25)/t17-,18- VFYMYMGVYBHBAW-IYARVYRRSA-N 50063294 CHEMBL349980::Pyrimidin-2-yl-{4-[2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-amine D(2) dopamine receptor Homo sapiens 240 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063294&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10570997 103958625 CHEMBL349980 ZINC13778710 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107841 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1 InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20- CEJURZXMIYUTSE-MXVIHJGJSA-N 50063291 CHEMBL78791::Thiophene-2-carboxylic acid {4-[2-(4-phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-amide D(2) dopamine receptor Homo sapiens 3.4 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596978 103958622 CHEMBL78791 ZINC13778680 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107842 COc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 InChI=1S/C23H33N5O/c1-29-22-9-7-21(8-10-22)28-17-15-27(16-18-28)14-11-19-3-5-20(6-4-19)26-23-24-12-2-13-25-23/h2,7-10,12-13,19-20H,3-6,11,14-18H2,1H3,(H,24,25,26)/t19-,20- KFWGIYRNIFINTL-MXVIHJGJSA-N 50063283 (4-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine::CHEMBL351617 D(2) dopamine receptor Homo sapiens 6 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786891 103958614 CHEMBL351617 ZINC13778700 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105702 CCCCN1CCN2C(C1)Cc1c[nH]c3cccc2c13 InChI=1S/C17H23N3/c1-2-3-7-19-8-9-20-14(12-19)10-13-11-18-15-5-4-6-16(20)17(13)15/h4-6,11,14,18H,2-3,7-10,12H2,1H3 HVAOTAPASCTPHK-UHFFFAOYSA-N 50019697 CHEMBL3286571 D(2) dopamine receptor Homo sapiens 110 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327219 103930620 CHEMBL3286571 ZINC27653072 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105703 CC(C)CN1CCN2C(C1)Cc1c[nH]c3cccc2c13 InChI=1S/C17H23N3/c1-12(2)10-19-6-7-20-14(11-19)8-13-9-18-15-4-3-5-16(20)17(13)15/h3-5,9,12,14,18H,6-8,10-11H2,1-2H3 DMGPDLSWGBDRHU-UHFFFAOYSA-N 50019698 CHEMBL3286572 D(2) dopamine receptor Homo sapiens 309 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327220 103930621 CHEMBL3286572 ZINC27650534 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105704 CCCCCN1CCN2C(C1)Cc1c[nH]c3cccc2c13 InChI=1S/C18H25N3/c1-2-3-4-8-20-9-10-21-15(13-20)11-14-12-19-16-6-5-7-17(21)18(14)16/h5-7,12,15,19H,2-4,8-11,13H2,1H3 RJWCQAKUQRSOTC-UHFFFAOYSA-N 50019699 CHEMBL3286573 D(2) dopamine receptor Homo sapiens 98 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019699&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327221 103930622 CHEMBL3286573 ZINC34801001 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105705 CC(C)CCN1CCN2C(C1)Cc1c[nH]c3cccc2c13 InChI=1S/C18H25N3/c1-13(2)6-7-20-8-9-21-15(12-20)10-14-11-19-16-4-3-5-17(21)18(14)16/h3-5,11,13,15,19H,6-10,12H2,1-2H3 FCALCRRTZHDENL-UHFFFAOYSA-N 50019700 CHEMBL3286574 D(2) dopamine receptor Homo sapiens 24 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019700&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327222 103930623 CHEMBL3286574 ZINC27653065 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105706 C(C1CCCCC1)N1CCN2C(C1)Cc1c[nH]c3cccc2c13 InChI=1S/C20H27N3/c1-2-5-15(6-3-1)13-22-9-10-23-17(14-22)11-16-12-21-18-7-4-8-19(23)20(16)18/h4,7-8,12,15,17,21H,1-3,5-6,9-11,13-14H2 FKYWQYRHUAFYJR-UHFFFAOYSA-N 50019701 CHEMBL3286575 D(2) dopamine receptor Homo sapiens 54 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019701&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53304086 103930624 CHEMBL3286575 ZINC27647733 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105709 C(N1CCN2C(C1)Cc1c[nH]c3cccc2c13)c1ccccc1-c1ccccc1 InChI=1S/C26H25N3/c1-2-7-19(8-3-1)23-10-5-4-9-20(23)17-28-13-14-29-22(18-28)15-21-16-27-24-11-6-12-25(29)26(21)24/h1-12,16,22,27H,13-15,17-18H2 VJYRFSZIRUISDG-UHFFFAOYSA-N 50019703 CHEMBL3286577 D(2) dopamine receptor Homo sapiens 450 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019703&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327261 103930626 CHEMBL3286577 ZINC27650261 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105711 C(N1CCN2C(C1)Cc1c[nH]c3cccc2c13)c1ccc(cc1)-c1ccccc1 InChI=1S/C26H25N3/c1-2-5-20(6-3-1)21-11-9-19(10-12-21)17-28-13-14-29-23(18-28)15-22-16-27-24-7-4-8-25(29)26(22)24/h1-12,16,23,27H,13-15,17-18H2 LBALZQQRFZMPJO-UHFFFAOYSA-N 50019705 CHEMBL3286579 D(2) dopamine receptor Homo sapiens 140 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019705&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327263 103930628 CHEMBL3286579 ZINC27651574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105712 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105713 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105715 O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4ccccc4)CC3)c2o1 InChI=1S/C24H23N3O2/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19/h1-11,16H,12-15,17H2,(H,25,28) CYGODHVAJQTCBG-UHFFFAOYSA-N 50241119 7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzooxazol-2-one::BIFEPRUNOX::CHEMBL218166 D(2) dopamine receptor Homo sapiens 2.3 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 208951 104098615 CHEMBL218166 DB04888 ZINC52971454 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107844 C(CN1CCN(CC1)c1cnccn1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C20H29N7/c1-7-23-20(24-8-1)25-18-4-2-17(3-5-18)6-11-26-12-14-27(15-13-26)19-16-21-9-10-22-19/h1,7-10,16-18H,2-6,11-15H2,(H,23,24,25)/t17-,18- JEEXKVNFXCLLCQ-IYARVYRRSA-N 50063293 CHEMBL165689::Pyrimidin-2-yl-{4-[2-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-ethyl]-cyclohexyl}-amine D(2) dopamine receptor Homo sapiens 180 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10785202 103958624 CHEMBL165689 ZINC13778712 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107849 C1CC(CCC1Nc1ncccn1)N1CCN(CC1)c1ccccc1 InChI=1S/C20H27N5/c1-2-5-18(6-3-1)24-13-15-25(16-14-24)19-9-7-17(8-10-19)23-20-21-11-4-12-22-20/h1-6,11-12,17,19H,7-10,13-16H2,(H,21,22,23) WEVXDKFRXWZSDU-UHFFFAOYSA-N 50063282 CHEMBL2110308::{4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 160 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497177 103958613 CHEMBL2110308 ZINC00601779 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107854 C(CN1CCN(CC1)c1ccncc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C21H30N6/c1-9-23-21(24-10-1)25-19-4-2-18(3-5-19)8-13-26-14-16-27(17-15-26)20-6-11-22-12-7-20/h1,6-7,9-12,18-19H,2-5,8,13-17H2,(H,23,24,25)/t18-,19- SBJAROVNDHTDKY-WGSAOQKQSA-N 50063290 CHEMBL166151::{4-[2-(4-Pyridin-4-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 4800 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618928 103958621 CHEMBL166151 ZINC12356193 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107860 C([C@H]1CC[C@@H](CC1)Nc1ncccn1)N1CCN(CC1)c1ccccc1 InChI=1S/C21H29N5/c1-2-5-20(6-3-1)26-15-13-25(14-16-26)17-18-7-9-19(10-8-18)24-21-22-11-4-12-23-21/h1-6,11-12,18-19H,7-10,13-17H2,(H,22,23,24)/t18-,19- WQFGYARLKCXPCQ-WGSAOQKQSA-N 50063295 CHEMBL165664::[4-(4-Phenyl-piperazin-1-ylmethyl)-cyclohexyl]-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 5.7 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063295&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10736673 103958626 CHEMBL165664 ZINC12356191 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107862 C(CN1CCc2ccccc2C1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C21H28N4/c1-2-5-19-16-25(15-11-18(19)4-1)14-10-17-6-8-20(9-7-17)24-21-22-12-3-13-23-21/h1-5,12-13,17,20H,6-11,14-16H2,(H,22,23,24)/t17-,20- BEKYXSCBRPYPCE-IRJFHVNHSA-N 50063278 CHEMBL165440::{4-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 110 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10854386 103958609 CHEMBL165440 ZINC12356153 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107864 CN([C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1ncccn1 InChI=1S/C23H33N5/c1-26(23-24-13-5-14-25-23)21-10-8-20(9-11-21)12-15-27-16-18-28(19-17-27)22-6-3-2-4-7-22/h2-7,13-14,20-21H,8-12,15-19H2,1H3/t20-,21- PIXTXCJJBIOUSC-MEMLXQNLSA-N 50063288 CHEMBL165047::Methyl-{4-[2-(4-phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 4.8 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063288&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11794122 103958619 CHEMBL165047 ZINC13778684 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107865 COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 InChI=1S/C23H33N5O/c1-29-22-6-3-2-5-21(22)28-17-15-27(16-18-28)14-11-19-7-9-20(10-8-19)26-23-24-12-4-13-25-23/h2-6,12-13,19-20H,7-11,14-18H2,1H3,(H,24,25,26)/t19-,20- HWSOAPGUROKPOX-MXVIHJGJSA-N 50063281 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine::CHEMBL164792 D(2) dopamine receptor Homo sapiens 3 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795011 103958612 CHEMBL164792 ZINC13778698 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107867 C(CN1CCN(CC1)c1cccnc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C21H30N6/c1-3-20(17-22-9-1)27-15-13-26(14-16-27)12-8-18-4-6-19(7-5-18)25-21-23-10-2-11-24-21/h1-3,9-11,17-19H,4-8,12-16H2,(H,23,24,25)/t18-,19- SIDPGTZGVQNXLM-WGSAOQKQSA-N 50063286 CHEMBL164723::{4-[2-(4-Pyridin-3-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10713960 103958617 CHEMBL164723 ZINC13778708 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107877 Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)Nc3ncccn3)CC2)c1Cl InChI=1S/C22H29Cl2N5/c23-19-3-1-4-20(21(19)24)29-15-13-28(14-16-29)12-9-17-5-7-18(8-6-17)27-22-25-10-2-11-26-22/h1-4,10-11,17-18H,5-9,12-16H2,(H,25,26,27)/t17-,18- FOQMHNUCQRZHMO-IYARVYRRSA-N 50063298 (4-{2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine::CHEMBL350352 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063298&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10598935 103958629 CHEMBL350352 ZINC13778696 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107880 CN(CC[C@H]1CC[C@@H](CC1)Nc1ncccn1)CCc1ccccc1 InChI=1S/C21H30N4/c1-25(16-12-18-6-3-2-4-7-18)17-13-19-8-10-20(11-9-19)24-21-22-14-5-15-23-21/h2-7,14-15,19-20H,8-13,16-17H2,1H3,(H,22,23,24)/t19-,20- OMLKVBCFEFXJLV-MXVIHJGJSA-N 50063287 CHEMBL164979::{4-[2-(Methyl-phenethyl-amino)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 39 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10712078 103958618 CHEMBL164979 ZINC13778691 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107883 C(CN1CCN(CC1)c1nccs1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C19H28N6S/c1-7-20-18(21-8-1)23-17-4-2-16(3-5-17)6-10-24-11-13-25(14-12-24)19-22-9-15-26-19/h1,7-9,15-17H,2-6,10-14H2,(H,20,21,23)/t16-,17- MTQWOJOFKUQLJW-QAQDUYKDSA-N 50063297 CHEMBL166252::Pyrimidin-2-yl-{4-[2-(4-thiazol-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-amine D(2) dopamine receptor Homo sapiens 46 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063297&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643047 103958628 CHEMBL166252 ZINC12356180 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107885 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)C1CCCCC1 InChI=1S/C25H39N3O/c29-25(22-7-3-1-4-8-22)26-23-13-11-21(12-14-23)15-16-27-17-19-28(20-18-27)24-9-5-2-6-10-24/h2,5-6,9-10,21-23H,1,3-4,7-8,11-20H2,(H,26,29)/t21-,23- XOMRUHWGUJNGLC-AFARHQOCSA-N 50063279 CHEMBL309623::Cyclohexanecarboxylic acid {4-[2-(4-phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-amide D(2) dopamine receptor Homo sapiens 38 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865584 103958610 CHEMBL309623 ZINC00601694 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107886 CCCN(CCC)CC[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C18H32N4/c1-3-13-22(14-4-2)15-10-16-6-8-17(9-7-16)21-18-19-11-5-12-20-18/h5,11-12,16-17H,3-4,6-10,13-15H2,1-2H3,(H,19,20,21)/t16-,17- QOGRQXGQKOEKKF-QAQDUYKDSA-N 50063299 CHEMBL165381::[4-(2-Dipropylamino-ethyl)-cyclohexyl]-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 2400 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10756932 103958630 CHEMBL165381 ZINC13778694 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50107889 C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20- OUUMPVSFLSOGJZ-MXVIHJGJSA-N 50063296 CHEMBL165679::{4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine D(2) dopamine receptor Homo sapiens 29 ChEMBL 10.1021/jm9707378 10.7270/Q20G3J97 9513604 Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3075615 103958627 CHEMBL165679 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105805 C(N1CCN2C(C1)Cc1c[nH]c3cccc2c13)c1ccccc1 InChI=1S/C20H21N3/c1-2-5-15(6-3-1)13-22-9-10-23-17(14-22)11-16-12-21-18-7-4-8-19(23)20(16)18/h1-8,12,17,21H,9-11,13-14H2 YPDPMVCWRIXMHS-UHFFFAOYSA-N 50019702 CHEMBL3286576 D(2) dopamine receptor Homo sapiens 130 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019702&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327260 103930625 CHEMBL3286576 ZINC27647722 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105807 C(N1CCN2C(C1)Cc1c[nH]c3cccc2c13)c1cccc(c1)-c1ccccc1 InChI=1S/C26H25N3/c1-2-7-20(8-3-1)21-9-4-6-19(14-21)17-28-12-13-29-23(18-28)15-22-16-27-24-10-5-11-25(29)26(22)24/h1-11,14,16,23,27H,12-13,15,17-18H2 YMYDUVXFUAIERG-UHFFFAOYSA-N 50019704 CHEMBL3286578 D(2) dopamine receptor Homo sapiens 0.650000 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019704&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327262 103930627 CHEMBL3286578 ZINC27651944 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105811 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 50056445 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea::CHEMBL157138::N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea::lisuride::lisuride, (S) D(2) dopamine receptor Homo sapiens 0.660000 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H8G 7WC7,7UM6,6DRX 28864 103952701 51164 CHEMBL157138 DB00589 43 ZINC03831001 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105877 C1CN2C(CN1)Cc1c[nH]c3cccc2c13 InChI=1S/C13H15N3/c1-2-11-13-9(7-15-11)6-10-8-14-4-5-16(10)12(13)3-1/h1-3,7,10,14-15H,4-6,8H2 FSAALEHYCCSDSA-UHFFFAOYSA-N 50019755 CHEMBL3286567 D(2) dopamine receptor Homo sapiens 2100 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 67325096 103930678 CHEMBL3286567 ZINC25965749 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105880 CN1CCN2C(C1)Cc1c[nH]c3cccc2c13 InChI=1S/C14H17N3/c1-16-5-6-17-11(9-16)7-10-8-15-12-3-2-4-13(17)14(10)12/h2-4,8,11,15H,5-7,9H2,1H3 SLMGXVGSOPZIFZ-UHFFFAOYSA-N 50019756 CHEMBL3286568 D(2) dopamine receptor Homo sapiens 660 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327181 103930679 CHEMBL3286568 ZINC25967580 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105882 CCN1CCN2C(C1)Cc1c[nH]c3cccc2c13 InChI=1S/C15H19N3/c1-2-17-6-7-18-12(10-17)8-11-9-16-13-4-3-5-14(18)15(11)13/h3-5,9,12,16H,2,6-8,10H2,1H3 GORHDCZLLBWZAU-UHFFFAOYSA-N 50019757 CHEMBL3286569 D(2) dopamine receptor Homo sapiens 140 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019757&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327217 103930680 CHEMBL3286569 ZINC25965563 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50105883 CCCN1CCN2C(C1)Cc1c[nH]c3cccc2c13 InChI=1S/C16H21N3/c1-2-6-18-7-8-19-13(11-18)9-12-10-17-14-4-3-5-15(19)16(12)14/h3-5,10,13,17H,2,6-9,11H2,1H3 WDTMSPNCLRUYLZ-UHFFFAOYSA-N 50019758 CHEMBL3286570 D(2) dopamine receptor Homo sapiens 570 ChEMBL 10.1021/jm5003759 10.7270/Q2D79D04 24878269 Krogsgaard-Larsen, N; Jensen, AA; Schrøder, TJ; Christoffersen, CT; Kehler, J University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019758&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327218 103930681 CHEMBL3286570 ZINC25966179 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110306 CC(C)(C)OC(=O)NCCCCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C20H31Cl2N3O2/c1-20(2,3)27-19(26)23-10-5-4-6-11-24-12-14-25(15-13-24)17-9-7-8-16(21)18(17)22/h7-9H,4-6,10-15H2,1-3H3,(H,23,26) RGAGEHAXWCECRD-UHFFFAOYSA-N 50021768 CHEMBL3298829 D(2) dopamine receptor Homo sapiens 43 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645287 103932466 CHEMBL3298829 ZINC02169412 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110307 COc1nc2sc(C(=O)NCCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)c(N)c2c(C)c1Cl InChI=1S/C25H30Cl3N5O2S/c1-15-18-21(29)22(36-25(18)31-24(35-2)19(15)27)23(34)30-9-4-3-5-10-32-11-13-33(14-12-32)17-8-6-7-16(26)20(17)28/h6-8H,3-5,9-14,29H2,1-2H3,(H,30,34) YPDIYQUBODHVII-UHFFFAOYSA-N 50021769 CHEMBL3298830 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021769&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645288 103932467 CHEMBL3298830 ZINC27861939 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110308 Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C25H31Cl2N5OS/c1-16-15-17(2)30-25-20(16)22(28)23(34-25)24(33)29-9-4-3-5-10-31-11-13-32(14-12-31)19-8-6-7-18(26)21(19)27/h6-8,15H,3-5,9-14,28H2,1-2H3,(H,29,33) YEDOJNFKHXVFHD-UHFFFAOYSA-N 50021770 CHEMBL3298895 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645289 103932468 CHEMBL3298895 ZINC27897939 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110309 COc1ccccc1N1CCN(CCCCCNC(=O)c2sc3nc(C)cc(C)c3c2N)CC1 InChI=1S/C26H35N5O2S/c1-18-17-19(2)29-26-22(18)23(27)24(34-26)25(32)28-11-7-4-8-12-30-13-15-31(16-14-30)20-9-5-6-10-21(20)33-3/h5-6,9-10,17H,4,7-8,11-16,27H2,1-3H3,(H,28,32) KUBIIYUHICAQBT-UHFFFAOYSA-N 50021771 CHEMBL3298896 D(2) dopamine receptor Homo sapiens 9.1 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645290 103932469 CHEMBL3298896 ZINC27894679 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110310 COc1nc2sc(C(=O)NCCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)c(N)c2c(C)c1Cl InChI=1S/C25H30Cl3N5O2S/c1-15-18-21(29)22(36-25(18)31-24(35-2)19(15)27)23(34)30-9-4-3-5-10-32-11-13-33(14-12-32)17-8-6-7-16(26)20(17)28/h6-8H,3-5,9-14,29H2,1-2H3,(H,30,34) YPDIYQUBODHVII-UHFFFAOYSA-N 50021769 CHEMBL3298830 D(2) dopamine receptor Homo sapiens 88 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021769&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645288 103932467 CHEMBL3298830 ZINC27861939 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110311 Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C25H31Cl2N5OS/c1-16-15-17(2)30-25-20(16)22(28)23(34-25)24(33)29-9-4-3-5-10-31-11-13-32(14-12-31)19-8-6-7-18(26)21(19)27/h6-8,15H,3-5,9-14,28H2,1-2H3,(H,29,33) YEDOJNFKHXVFHD-UHFFFAOYSA-N 50021770 CHEMBL3298895 D(2) dopamine receptor Homo sapiens 0.300000 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645289 103932468 CHEMBL3298895 ZINC27897939 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110312 Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C25H31Cl2N5OS/c1-16-15-17(2)30-25-20(16)22(28)23(34-25)24(33)29-9-4-3-5-10-31-11-13-32(14-12-31)19-8-6-7-18(26)21(19)27/h6-8,15H,3-5,9-14,28H2,1-2H3,(H,29,33) YEDOJNFKHXVFHD-UHFFFAOYSA-N 50021770 CHEMBL3298895 D(2) dopamine receptor Homo sapiens 13 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645289 103932468 CHEMBL3298895 ZINC27897939 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110313 OC1(CCNCC1)c1ccc(Cl)cc1 InChI=1S/C11H14ClNO/c12-10-3-1-9(2-4-10)11(14)5-7-13-8-6-11/h1-4,13-14H,5-8H2 LZAYOZUFUAMFLD-UHFFFAOYSA-N 50021772 CHEMBL3298755 D(2) dopamine receptor Homo sapiens 9090 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 38282 103932470 CHEMBL3298755 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110314 CC(C)(C)OC(=O)NCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C18H27ClN2O3/c1-17(2,3)24-16(22)20-10-13-21-11-8-18(23,9-12-21)14-4-6-15(19)7-5-14/h4-7,23H,8-13H2,1-3H3,(H,20,22) BHOHPRFNAQMPCI-UHFFFAOYSA-N 50021773 CHEMBL3298756 D(2) dopamine receptor Homo sapiens 2750 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645291 103932471 CHEMBL3298756 ZINC29321533 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110315 CC(C)(C)OC(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C19H29ClN2O3/c1-18(2,3)25-17(23)21-11-4-12-22-13-9-19(24,10-14-22)15-5-7-16(20)8-6-15/h5-8,24H,4,9-14H2,1-3H3,(H,21,23) ZHCQTOYNHYNIPE-UHFFFAOYSA-N 50021774 CHEMBL3298757 D(2) dopamine receptor Homo sapiens 1350 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645292 103932472 CHEMBL3298757 ZINC27979858 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110316 CC(C)(C)OC(=O)NCCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C20H31ClN2O3/c1-19(2,3)26-18(24)22-12-4-5-13-23-14-10-20(25,11-15-23)16-6-8-17(21)9-7-16/h6-9,25H,4-5,10-15H2,1-3H3,(H,22,24) WQIQKJZEKYFKAS-UHFFFAOYSA-N 50021775 CHEMBL3298825 D(2) dopamine receptor Homo sapiens 2110 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645293 103932473 CHEMBL3298825 ZINC36093403 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110317 CC(C)(C)OC(=O)NCCCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C21H33ClN2O3/c1-20(2,3)27-19(25)23-13-5-4-6-14-24-15-11-21(26,12-16-24)17-7-9-18(22)10-8-17/h7-10,26H,4-6,11-16H2,1-3H3,(H,23,25) RZIVHWYBTWTWME-UHFFFAOYSA-N 50021788 CHEMBL3299091 D(2) dopamine receptor Homo sapiens 2050 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645294 103932486 CHEMBL3299091 ZINC28107014 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110318 CC(C)(C)OC(=O)NCCCCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C22H35ClN2O3/c1-21(2,3)28-20(26)24-14-6-4-5-7-15-25-16-12-22(27,13-17-25)18-8-10-19(23)11-9-18/h8-11,27H,4-7,12-17H2,1-3H3,(H,24,26) TUZNGRNEPJAFOL-UHFFFAOYSA-N 50021789 CHEMBL3299092 D(2) dopamine receptor Homo sapiens 902 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645295 103932487 CHEMBL3299092 ZINC28109531 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110319 COc1ccccc1N1CCNCC1 InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 VNZLQLYBRIOLFZ-UHFFFAOYSA-N 50001862 (N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl)-piperazine::1-(2-Methoxy-phenyl)-piperazine::2-METHOXYPHENYLPIPERAZINE::4-(2-Methoxy-phenyl)-piperazin-1-ium::CHEMBL9666 D(2) dopamine receptor Homo sapiens 4110 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1346 103916229 CHEMBL9666 280 ZINC00012687 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110321 COc1ccccc1N1CCN(CCCNC(=O)OC(C)(C)C)CC1 InChI=1S/C19H31N3O3/c1-19(2,3)25-18(23)20-10-7-11-21-12-14-22(15-13-21)16-8-5-6-9-17(16)24-4/h5-6,8-9H,7,10-15H2,1-4H3,(H,20,23) LJPFHXAKXNKRIV-UHFFFAOYSA-N 50021796 CHEMBL3299094 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57420188 103932494 CHEMBL3299094 ZINC28096373 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110322 COc1ccccc1N1CCN(CCCCNC(=O)OC(C)(C)C)CC1 InChI=1S/C20H33N3O3/c1-20(2,3)26-19(24)21-11-7-8-12-22-13-15-23(16-14-22)17-9-5-6-10-18(17)25-4/h5-6,9-10H,7-8,11-16H2,1-4H3,(H,21,24) KONGZRYXSLUXFB-UHFFFAOYSA-N 50021800 CHEMBL3299095 D(2) dopamine receptor Homo sapiens 19 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 58765508 103932498 CHEMBL3299095 ZINC36153350 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110323 COc1ccccc1N1CCN(CCCCCNC(=O)OC(C)(C)C)CC1 InChI=1S/C21H35N3O3/c1-21(2,3)27-20(25)22-12-8-5-9-13-23-14-16-24(17-15-23)18-10-6-7-11-19(18)26-4/h6-7,10-11H,5,8-9,12-17H2,1-4H3,(H,22,25) VKNBNIUPOKNKDJ-UHFFFAOYSA-N 50021802 CHEMBL3299096 D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645297 103932500 CHEMBL3299096 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110324 COc1ccccc1N1CCN(CCCCCCNC(=O)OC(C)(C)C)CC1 InChI=1S/C22H37N3O3/c1-22(2,3)28-21(26)23-13-9-5-6-10-14-24-15-17-25(18-16-24)19-11-7-8-12-20(19)27-4/h7-8,11-12H,5-6,9-10,13-18H2,1-4H3,(H,23,26) MDOWWNIPKFDTJY-UHFFFAOYSA-N 50021805 CHEMBL3299097 D(2) dopamine receptor Homo sapiens 75 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645298 103932503 CHEMBL3299097 ZINC36153326 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110325 Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C23H27ClN4O2S/c1-14-13-15(2)27-22-18(14)19(25)20(31-22)21(29)26-9-12-28-10-7-23(30,8-11-28)16-3-5-17(24)6-4-16/h3-6,13,30H,7-12,25H2,1-2H3,(H,26,29) KGFRNHHUAVUXQB-UHFFFAOYSA-N 50021806 CHEMBL3299098 D(2) dopamine receptor Homo sapiens 910 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645299 103932504 CHEMBL3299098 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110326 Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C24H29ClN4O2S/c1-15-14-16(2)28-23-19(15)20(26)21(32-23)22(30)27-10-3-11-29-12-8-24(31,9-13-29)17-4-6-18(25)7-5-17/h4-7,14,31H,3,8-13,26H2,1-2H3,(H,27,30) AWYHXTJQEWRWOA-UHFFFAOYSA-N 50021810 CHEMBL3299099 D(2) dopamine receptor Homo sapiens 1700 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645300 103932508 CHEMBL3299099 ZINC28250341 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110327 Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C25H31ClN4O2S/c1-16-15-17(2)29-24-20(16)21(27)22(33-24)23(31)28-11-3-4-12-30-13-9-25(32,10-14-30)18-5-7-19(26)8-6-18/h5-8,15,32H,3-4,9-14,27H2,1-2H3,(H,28,31) MWEMZAUJQVTCGX-UHFFFAOYSA-N 50021811 CHEMBL3298200 D(2) dopamine receptor Homo sapiens 2250 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645301 103932509 CHEMBL3298200 ZINC28243705 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110328 Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C26H33ClN4O2S/c1-17-16-18(2)30-25-21(17)22(28)23(34-25)24(32)29-12-4-3-5-13-31-14-10-26(33,11-15-31)19-6-8-20(27)9-7-19/h6-9,16,33H,3-5,10-15,28H2,1-2H3,(H,29,32) FBWAJWVVFJJYLR-UHFFFAOYSA-N 50021813 CHEMBL3298685 D(2) dopamine receptor Homo sapiens 1980 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645302 103932511 CHEMBL3298685 ZINC28244256 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110329 Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 InChI=1S/C27H35ClN4O2S/c1-18-17-19(2)31-26-22(18)23(29)24(35-26)25(33)30-13-5-3-4-6-14-32-15-11-27(34,12-16-32)20-7-9-21(28)10-8-20/h7-10,17,34H,3-6,11-16,29H2,1-2H3,(H,30,33) GWZPCOVXCOPKJA-UHFFFAOYSA-N 50021814 CHEMBL3298686 D(2) dopamine receptor Homo sapiens 975 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645303 103932512 CHEMBL3298686 ZINC28255087 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110330 COc1ccccc1N1CCN(CCNC(=O)c2sc3nc(OC)c(Cl)c(C)c3c2N)CC1 InChI=1S/C23H28ClN5O3S/c1-14-17-19(25)20(33-23(17)27-22(32-3)18(14)24)21(30)26-8-9-28-10-12-29(13-11-28)15-6-4-5-7-16(15)31-2/h4-7H,8-13,25H2,1-3H3,(H,26,30) MAPGIJMBSHARKF-UHFFFAOYSA-N 50021815 CHEMBL3298758 D(2) dopamine receptor Homo sapiens 48 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645304 103932513 CHEMBL3298758 ZINC36080062 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110331 COc1ccccc1N1CCN(CCCNC(=O)c2sc3nc(OC)c(Cl)c(C)c3c2N)CC1 InChI=1S/C24H30ClN5O3S/c1-15-18-20(26)21(34-24(18)28-23(33-3)19(15)25)22(31)27-9-6-10-29-11-13-30(14-12-29)16-7-4-5-8-17(16)32-2/h4-5,7-8H,6,9-14,26H2,1-3H3,(H,27,31) WRFRTCQJMMIOLF-UHFFFAOYSA-N 50021816 CHEMBL3298759 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645305 103932514 CHEMBL3298759 ZINC49606034 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110332 COc1ccccc1N1CCN(CCCCNC(=O)c2sc3nc(OC)c(Cl)c(C)c3c2N)CC1 InChI=1S/C25H32ClN5O3S/c1-16-19-21(27)22(35-25(19)29-24(34-3)20(16)26)23(32)28-10-6-7-11-30-12-14-31(15-13-30)17-8-4-5-9-18(17)33-2/h4-5,8-9H,6-7,10-15,27H2,1-3H3,(H,28,32) RULOOZJTFYDVKV-UHFFFAOYSA-N 50021817 CHEMBL3298826 D(2) dopamine receptor Homo sapiens 6.3 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645306 103932515 CHEMBL3298826 ZINC28255093 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110333 COc1ccccc1N1CCN(CCCCCNC(=O)c2sc3nc(OC)c(Cl)c(C)c3c2N)CC1 InChI=1S/C26H34ClN5O3S/c1-17-20-22(28)23(36-26(20)30-25(35-3)21(17)27)24(33)29-11-7-4-8-12-31-13-15-32(16-14-31)18-9-5-6-10-19(18)34-2/h5-6,9-10H,4,7-8,11-16,28H2,1-3H3,(H,29,33) HNFWRWQITYFMNA-UHFFFAOYSA-N 50021818 CHEMBL3298827 D(2) dopamine receptor Homo sapiens 3.5 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645307 103932516 CHEMBL3298827 ZINC28252767 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110334 COc1nc2sc(C(=O)NCCCCCCN3CCC(CC3)c3ccc(Cl)cc3)c(N)c2c(C)c1Cl InChI=1S/C27H34Cl2N4O2S/c1-17-21-23(30)24(36-27(21)32-26(35-2)22(17)29)25(34)31-13-5-3-4-6-14-33-15-11-19(12-16-33)18-7-9-20(28)10-8-18/h7-10,19H,3-6,11-16,30H2,1-2H3,(H,31,34) VDABMKZNXMFUQE-UHFFFAOYSA-N 50021819 CHEMBL3298828 D(2) dopamine receptor Homo sapiens 0.600000 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645308 242042348 CHEMBL3298828 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110342 COc1ccccc1N1CCN(CCNC(=O)OC(C)(C)C)CC1 InChI=1S/C18H29N3O3/c1-18(2,3)24-17(22)19-9-10-20-11-13-21(14-12-20)15-7-5-6-8-16(15)23-4/h5-8H,9-14H2,1-4H3,(H,19,22) CJBOUVOUANDQQO-UHFFFAOYSA-N 50021791 CHEMBL3299093 D(2) dopamine receptor Homo sapiens 170 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645296 103932489 CHEMBL3299093 ZINC28110189 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110357 Clc1cccc(N2CCNCC2)c1Cl InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2 UDQMXYJSNNCRAS-UHFFFAOYSA-N 50394930 CHEMBL1424807 D(2) dopamine receptor Homo sapiens 1160 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 851833 163343954 CHEMBL1424807 ZINC00386729 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110362 COc1ccccc1N1CCNCC1 InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 VNZLQLYBRIOLFZ-UHFFFAOYSA-N 50001862 (N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl)-piperazine::1-(2-Methoxy-phenyl)-piperazine::2-METHOXYPHENYLPIPERAZINE::4-(2-Methoxy-phenyl)-piperazin-1-ium::CHEMBL9666 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1346 103916229 CHEMBL9666 280 ZINC00012687 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110363 COc1ccccc1N1CCN(CCNC(=O)OC(C)(C)C)CC1 InChI=1S/C18H29N3O3/c1-18(2,3)24-17(22)19-9-10-20-11-13-21(14-12-20)15-7-5-6-8-16(15)23-4/h5-8H,9-14H2,1-4H3,(H,19,22) CJBOUVOUANDQQO-UHFFFAOYSA-N 50021791 CHEMBL3299093 D(2) dopamine receptor Homo sapiens 93 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645296 103932489 CHEMBL3299093 ZINC28110189 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110364 COc1ccccc1N1CCN(CCCCCCNC(=O)OC(C)(C)C)CC1 InChI=1S/C22H37N3O3/c1-22(2,3)28-21(26)23-13-9-5-6-10-14-24-15-17-25(18-16-24)19-11-7-8-12-20(19)27-4/h7-8,11-12H,5-6,9-10,13-18H2,1-4H3,(H,23,26) MDOWWNIPKFDTJY-UHFFFAOYSA-N 50021805 CHEMBL3299097 D(2) dopamine receptor Homo sapiens 4.0 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645298 103932503 CHEMBL3299097 ZINC36153326 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110368 COc1ccccc1N1CCN(CCCNC(=O)OC(C)(C)C)CC1 InChI=1S/C19H31N3O3/c1-19(2,3)25-18(23)20-10-7-11-21-12-14-22(15-13-21)16-8-5-6-9-17(16)24-4/h5-6,8-9H,7,10-15H2,1-4H3,(H,20,23) LJPFHXAKXNKRIV-UHFFFAOYSA-N 50021796 CHEMBL3299094 D(2) dopamine receptor Homo sapiens 0.390000 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57420188 103932494 CHEMBL3299094 ZINC28096373 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110369 COc1ccccc1N1CCN(CCCCNC(=O)OC(C)(C)C)CC1 InChI=1S/C20H33N3O3/c1-20(2,3)26-19(24)21-11-7-8-12-22-13-15-23(16-14-22)17-9-5-6-10-18(17)25-4/h5-6,9-10H,7-8,11-16H2,1-4H3,(H,21,24) KONGZRYXSLUXFB-UHFFFAOYSA-N 50021800 CHEMBL3299095 D(2) dopamine receptor Homo sapiens 0.600000 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 58765508 103932498 CHEMBL3299095 ZINC36153350 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110370 COc1ccccc1N1CCN(CCCCCNC(=O)OC(C)(C)C)CC1 InChI=1S/C21H35N3O3/c1-21(2,3)27-20(25)22-12-8-5-9-13-23-14-16-24(17-15-23)18-10-6-7-11-19(18)26-4/h6-7,10-11H,5,8-9,12-17H2,1-4H3,(H,22,25) VKNBNIUPOKNKDJ-UHFFFAOYSA-N 50021802 CHEMBL3299096 D(2) dopamine receptor Homo sapiens 1.4 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645297 103932500 CHEMBL3299096 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110371 COc1ccccc1N1CCN(CCCCCNC(=O)c2sc3nc(OC)c(Cl)c(C)c3c2N)CC1 InChI=1S/C26H34ClN5O3S/c1-17-20-22(28)23(36-26(20)30-25(35-3)21(17)27)24(33)29-11-7-4-8-12-31-13-15-32(16-14-31)18-9-5-6-10-19(18)34-2/h5-6,9-10H,4,7-8,11-16,28H2,1-3H3,(H,29,33) HNFWRWQITYFMNA-UHFFFAOYSA-N 50021818 CHEMBL3298827 D(2) dopamine receptor Homo sapiens 2.7 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645307 103932516 CHEMBL3298827 ZINC28252767 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50110372 COc1nc2sc(C(=O)NCCCCCCN3CCC(CC3)c3ccc(Cl)cc3)c(N)c2c(C)c1Cl InChI=1S/C27H34Cl2N4O2S/c1-17-21-23(30)24(36-27(21)32-26(35-2)22(17)29)25(34)31-13-5-3-4-6-14-33-15-11-19(12-16-33)18-7-9-20(28)10-8-18/h7-10,19H,3-6,11-16,30H2,1-2H3,(H,31,34) VDABMKZNXMFUQE-UHFFFAOYSA-N 50021819 CHEMBL3298828 D(2) dopamine receptor Homo sapiens 5.5 ChEMBL 10.1021/jm500457x 10.7270/Q29Z96FS 24827597 Szabo, M; Klein Herenbrink, C; Christopoulos, A; Lane, JR; Capuano, B Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90645308 242042348 CHEMBL3298828 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018869 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018871 C[Si](C)(C)c1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12 InChI=1S/C21H27ClN4Si/c1-27(2,3)21-6-4-5-20-17(15-23-26(20)21)16-24-11-13-25(14-12-24)19-9-7-18(22)8-10-19/h4-10,15H,11-14,16H2,1-3H3 VLCYCTQMMKCUDI-UHFFFAOYSA-N 50109947 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-trimethylsilanyl-pyrazolo[1,5-a]pyridine::CHEMBL160454 D(2) dopamine receptor Homo sapiens 2800 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372338 104004835 CHEMBL160454 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018874 Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)C#C)CC1 InChI=1S/C20H19ClN4/c1-2-18-4-3-5-20-16(14-22-25(18)20)15-23-10-12-24(13-11-23)19-8-6-17(21)7-9-19/h1,3-9,14H,10-13,15H2 NVYMBZSBOQRSFH-UHFFFAOYSA-N 50109952 3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-7-ethynyl-pyrazolo[1,5-a]pyridine::3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-ethynyl-pyrazolo[1,5-a]pyridine::4-(4-Chloro-phenyl)-1-(7-ethynyl-pyrazolo[1,5-a]pyridin-3-ylmethyl)-piperazin-1-ium::CHEMBL160952 D(2) dopamine receptor Homo sapiens 6200 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10427977 104004840 CHEMBL160952 ZINC13438650 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018876 Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)-c2ccccc2)CC1 InChI=1S/C24H23ClN4/c25-21-9-11-22(12-10-21)28-15-13-27(14-16-28)18-20-17-26-29-23(7-4-8-24(20)29)19-5-2-1-3-6-19/h1-12,17H,13-16,18H2 XDYCBVKXSXIDCW-UHFFFAOYSA-N 50109942 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phenyl-pyrazolo[1,5-a]pyridine::CHEMBL155913 D(2) dopamine receptor Homo sapiens 2800 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372009 104004830 CHEMBL155913 ZINC13438656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018877 Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C30H35ClN6/c1-24-28(23-34-14-18-35(19-15-34)27-12-10-26(31)11-13-27)29-8-5-9-30(37(29)32-24)36-20-16-33(17-21-36)22-25-6-3-2-4-7-25/h2-13H,14-23H2,1H3 OHHKPQVUUXXVGV-UHFFFAOYSA-N 50109955 7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-pyrazolo[1,5-a]pyridine::CHEMBL160536 D(2) dopamine receptor Homo sapiens 300 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371980 104004843 CHEMBL160536 ZINC13438671 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018878 OCc1ccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn2c1 InChI=1S/C19H21ClN4O/c20-17-2-4-18(5-3-17)23-9-7-22(8-10-23)13-16-11-21-24-12-15(14-25)1-6-19(16)24/h1-6,11-12,25H,7-10,13-14H2 SAPCLYRXCUDCRV-UHFFFAOYSA-N 50109954 (3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridin-6-yl)methanol::CHEMBL345357::{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridin-6-yl}-methanol D(2) dopamine receptor Homo sapiens 22000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372296 104004842 CHEMBL345357 ZINC13438686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018879 Clc1ccc(cc1)N1CCN(Cc2cnn3c(C=O)cccc23)CC1 InChI=1S/C19H19ClN4O/c20-16-4-6-17(7-5-16)23-10-8-22(9-11-23)13-15-12-21-24-18(14-25)2-1-3-19(15)24/h1-7,12,14H,8-11,13H2 JQJZAUBSLUYDAA-UHFFFAOYSA-N 50109950 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-7-carbaldehyde::CHEMBL346805 D(2) dopamine receptor Homo sapiens 9200 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371932 104004838 CHEMBL346805 ZINC13438680 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018883 Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#N InChI=1S/C20H20ClN5/c1-15-19(20-4-2-3-18(13-22)26(20)23-15)14-24-9-11-25(12-10-24)17-7-5-16(21)6-8-17/h2-8H,9-12,14H2,1H3 MFGYZKGJWDJWAA-UHFFFAOYSA-N 50109945 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-pyrazolo[1,5-a]pyridine-7-carbonitrile::CHEMBL160932 D(2) dopamine receptor Homo sapiens 58000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361512 104004833 CHEMBL160932 ZINC13438674 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018887 Cc1cccn2ncc(CN3CCN(CC3)c3ccc(Cl)cc3)c12 InChI=1S/C19H21ClN4/c1-15-3-2-8-24-19(15)16(13-21-24)14-22-9-11-23(12-10-22)18-6-4-17(20)5-7-18/h2-8,13H,9-12,14H2,1H3 FVQOIDZBAPLYGQ-UHFFFAOYSA-N 50109953 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4-methyl-pyrazolo[1,5-a]pyridine::4-(4-Chloro-phenyl)-1-(4-methyl-pyrazolo[1,5-a]pyridin-3-ylmethyl)-piperazin-1-ium::CHEMBL156369 D(2) dopamine receptor Homo sapiens 13000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44270444 104004841 CHEMBL156369 ZINC13438689 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018890 OCc1cccn2ncc(CN3CCN(CC3)c3ccc(Cl)cc3)c12 InChI=1S/C19H21ClN4O/c20-17-3-5-18(6-4-17)23-10-8-22(9-11-23)13-16-12-21-24-7-1-2-15(14-25)19(16)24/h1-7,12,25H,8-11,13-14H2 AYTNWERJAAXIPL-UHFFFAOYSA-N 50109951 CHEMBL160396::{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridin-4-yl}-methanol D(2) dopamine receptor Homo sapiens 56000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372312 104004839 CHEMBL160396 ZINC13438683 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018892 Cc1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12 InChI=1S/C19H21ClN4/c1-15-3-2-4-19-16(13-21-24(15)19)14-22-9-11-23(12-10-22)18-7-5-17(20)6-8-18/h2-8,13H,9-12,14H2,1H3 UIYATCKYXWPCQG-UHFFFAOYSA-N 50109941 3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-7-methylH-pyrazolo[1,5-a]pyridine::3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-methyl-pyrazolo[1,5-a]pyridine::4-(4-Chloro-phenyl)-1-(7-methyl-pyrazolo[1,5-a]pyridin-3-ylmethyl)-piperazin-1-ium::CHEMBL423247 D(2) dopamine receptor Homo sapiens 4900 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44270558 104004829 CHEMBL423247 ZINC13438677 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50018893 Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)N2CCN(Cc3ccccc3)CC2)CC1 InChI=1S/C29H33ClN6/c30-26-9-11-27(12-10-26)34-17-13-33(14-18-34)23-25-21-31-36-28(25)7-4-8-29(36)35-19-15-32(16-20-35)22-24-5-2-1-3-6-24/h1-12,21H,13-20,22-23H2 GYWHDZIJHYATFG-UHFFFAOYSA-N 50109949 7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL160266 D(2) dopamine receptor Homo sapiens 400 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371996 104004837 CHEMBL160266 ZINC13438668 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50587913 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OGJGQVFWEPNYSB-UHFFFAOYSA-N 85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853 D(2) dopamine receptor Homo sapiens 54000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L74 6IQL 5311200 136351193 CHEMBL555670CHEMBL267014 3303 ZINC25760037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50587914 Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C25H25ClN4/c1-19-23(18-28-14-16-29(17-15-28)22-12-10-21(26)11-13-22)25-9-5-8-24(30(25)27-19)20-6-3-2-4-7-20/h2-13H,14-18H2,1H3 JQBYEGVGELAAOI-UHFFFAOYSA-N 50109946 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-7-phenyl-pyrazolo[1,5-a]pyridine::CHEMBL351550 D(2) dopamine receptor Homo sapiens 24000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372153 104004834 CHEMBL351550 ZINC13438659 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50587915 Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccc(F)cc1 InChI=1S/C25H24ClFN4/c1-18-23(17-29-13-15-30(16-14-29)22-11-7-20(26)8-12-22)25-4-2-3-24(31(25)28-18)19-5-9-21(27)10-6-19/h2-12H,13-17H2,1H3 NSRMSZBPAQTJBS-UHFFFAOYSA-N 50109948 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-fluoro-phenyl)-2-methyl-pyrazolo[1,5-a]pyridine::CHEMBL160749 D(2) dopamine receptor Homo sapiens 16000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372154 104004836 CHEMBL160749 ZINC13438665 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50587917 Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#C InChI=1S/C21H21ClN4/c1-3-18-5-4-6-21-20(16(2)23-26(18)21)15-24-11-13-25(14-12-24)19-9-7-17(22)8-10-19/h1,4-10H,11-15H2,2H3 RZAVUFOOSFLHIY-UHFFFAOYSA-N 50109944 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-ethynyl-2-methyl-pyrazolo[1,5-a]pyridine::CHEMBL156851 D(2) dopamine receptor Homo sapiens 21000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371997 104004832 CHEMBL156851 ZINC13438653 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50587918 Fc1ccc(cc1)-c1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12 InChI=1S/C24H22ClFN4/c25-20-6-10-22(11-7-20)29-14-12-28(13-15-29)17-19-16-27-30-23(2-1-3-24(19)30)18-4-8-21(26)9-5-18/h1-11,16H,12-15,17H2 LAZCWDPLJFPPDI-UHFFFAOYSA-N 50109956 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-fluoro-phenyl)-pyrazolo[1,5-a]pyridine::CHEMBL156198 D(2) dopamine receptor Homo sapiens 15000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372198 104004844 CHEMBL156198 ZINC13438662 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50587919 Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1 InChI=1S/C18H19ClN4/c19-16-4-6-17(7-5-16)22-11-9-21(10-12-22)14-15-13-20-23-8-2-1-3-18(15)23/h1-8,13H,9-12,14H2 XVPRVMIFXXOEFR-UHFFFAOYSA-N 50073805 3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine::3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::4-(4-Chloro-phenyl)-1-pyrazolo[1,5-a]pyridin-3-ylmethyl-piperazin-1-ium::CHEMBL7927::FAUC 113 D(2) dopamine receptor Homo sapiens 3200 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10404144 103967091 CHEMBL7927 ZINC13438692 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50587921 Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)C#N)CC1 InChI=1S/C19H18ClN5/c20-16-4-6-17(7-5-16)24-10-8-23(9-11-24)14-15-13-22-25-18(12-21)2-1-3-19(15)25/h1-7,13H,8-11,14H2 STIRDGXSGQTCAJ-UHFFFAOYSA-N 50109943 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-7-carbonitrile::CHEMBL160626 D(2) dopamine receptor Homo sapiens 44000 ChEMBL 10.1016/s0960-894x(01)00814-9 10.7270/Q2JM2B5X 11844688 Lober, S; Aboul-Fadl, T; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11725531 104004831 CHEMBL160626 ZINC52617467 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50017014 CCCN(CCC)[C@H]1CCc2nn3ccccc3c2C1 InChI=1S/C17H25N3/c1-3-10-19(11-4-2)14-8-9-16-15(13-14)17-7-5-6-12-20(17)18-16/h5-7,12,14H,3-4,8-11,13H2,1-2H3/t14-/m0/s1 PWWITWFCENNJEP-AWEZNQCLSA-N 50116767 CHEMBL310867::Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indazol-2-yl-amine D(2) dopamine receptor Homo sapiens 85 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116767&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084583 104010406 CHEMBL310867 ZINC13817114 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50017018 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Homo sapiens 40 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50017021 CCCN1CCc2nn3ccccc3c2C1 InChI=1S/C13H17N3/c1-2-7-15-9-6-12-11(10-15)13-5-3-4-8-16(13)14-12/h3-5,8H,2,6-7,9-10H2,1H3 URWBDIMBZFWGSF-UHFFFAOYSA-N 50116765 3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene::CHEMBL80845 D(2) dopamine receptor Homo sapiens 230 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316315 104010404 CHEMBL80845 ZINC12355903 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50211106 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Homo sapiens 9 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499447 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2[nH]1 InChI=1S/C28H33N5OS/c34-28(25-19-21-5-1-3-7-24(21)30-25)29-22-11-9-20(10-12-22)13-14-32-15-17-33(18-16-32)27-23-6-2-4-8-26(23)35-31-27/h1-8,19-20,22,30H,9-18H2,(H,29,34)/t20-,22- KXAOPEMSBPZNPQ-AQYVVDRMSA-N 50207116 CHEMBL3905247::US9550741, I-4 D(2) dopamine receptor Homo sapiens 0.430 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207116&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342194 375981448 CHEMBL3905247 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499455 Brc1ccsc1C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C24H29BrN4OS2/c25-20-10-16-31-22(20)24(30)26-18-7-5-17(6-8-18)9-11-28-12-14-29(15-13-28)23-19-3-1-2-4-21(19)32-27-23/h1-4,10,16-18H,5-9,11-15H2,(H,26,30)/t17-,18- OHRWBHSKZIDRDQ-IYARVYRRSA-N 263378 US9550741, I-12 D(2) dopamine receptor Homo sapiens 3.15 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342267 377002285 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499456 CCc1c(sc2ccccc12)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C30H36N4OS2/c1-2-23-24-7-3-5-9-26(24)36-28(23)30(35)31-22-13-11-21(12-14-22)15-16-33-17-19-34(20-18-33)29-25-8-4-6-10-27(25)37-32-29/h3-10,21-22H,2,11-20H2,1H3,(H,31,35)/t21-,22- POWWHPJOZGHCEW-HZCBDIJESA-N 263379 US9550741, I-13::trans-N-(4-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)cyclohexyl)-3-ethylbenzo[b]thienyl-2-carboxamide D(2) dopamine receptor Homo sapiens 1.78 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121254132 377002286 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499458 [O-][N+](=O)c1ccc2[nH]c(cc2c1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 263381 US9550741, I-15 D(2) dopamine receptor Homo sapiens 21.3 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342231 377002288 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499459 COc1ccc2oc(cc2c1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C29H34N4O3S/c1-35-23-10-11-25-21(18-23)19-26(36-25)29(34)30-22-8-6-20(7-9-22)12-13-32-14-16-33(17-15-32)28-24-4-2-3-5-27(24)37-31-28/h2-5,10-11,18-20,22H,6-9,12-17H2,1H3,(H,30,34)/t20-,22- UEUHNMQUIFFWEA-AQYVVDRMSA-N 263382 US9550741, I-16 D(2) dopamine receptor Homo sapiens 1.05 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118935078 377002289 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499460 O=C(Cc1cccs1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C25H32N4OS2/c30-24(18-21-4-3-17-31-21)26-20-9-7-19(8-10-20)11-12-28-13-15-29(16-14-28)25-22-5-1-2-6-23(22)32-27-25/h1-6,17,19-20H,7-16,18H2,(H,26,30)/t19-,20- DGUPLZWUXDQFTF-MXVIHJGJSA-N 263383 US9550741, I-17 D(2) dopamine receptor Homo sapiens 0.270 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342295 377002290 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499461 O=C(Cc1coc2ccccc12)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C29H34N4O2S/c34-28(19-22-20-35-26-7-3-1-5-24(22)26)30-23-11-9-21(10-12-23)13-14-32-15-17-33(18-16-32)29-25-6-2-4-8-27(25)36-31-29/h1-8,20-21,23H,9-19H2,(H,30,34)/t21-,23- YRFHSWLWNMFJNN-AFARHQOCSA-N 263384 US9550741, I-18 D(2) dopamine receptor Homo sapiens 0.230 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263384&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118935073 377002291 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499465 O=C(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2ccccc2[nH]1 263388 US9550741, I-22 D(2) dopamine receptor Homo sapiens 1.90 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263388&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342194 377002295 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499474 O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccc(o1)[N+]#[C-] InChI=1S/C24H29N5O3S2/c1-25-22-10-11-23(32-22)34(30,31)27-19-8-6-18(7-9-19)12-13-28-14-16-29(17-15-28)24-20-4-2-3-5-21(20)33-26-24/h2-5,10-11,18-19,27H,6-9,12-17H2/t18-,19- FJGIJPVLRUOQFB-WGSAOQKQSA-N 263397 US9550741, II-7 D(2) dopamine receptor Homo sapiens 8.54 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135120969 377002304 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499476 Cc1ccc(o1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C24H32N4O3S2/c1-18-6-11-23(31-18)33(29,30)26-20-9-7-19(8-10-20)12-13-27-14-16-28(17-15-27)24-21-4-2-3-5-22(21)32-25-24/h2-6,11,19-20,26H,7-10,12-17H2,1H3/t19-,20- LFOIYGHYJZAMLX-MXVIHJGJSA-N 263399 US9550741, II-9 D(2) dopamine receptor Homo sapiens 7.38 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263399&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86341997 377002306 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499479 O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cc2cc(ccc2s1)[N+]#[C-] InChI=1S/C28H31N5O2S3/c1-29-23-10-11-25-21(18-23)19-27(36-25)38(34,35)31-22-8-6-20(7-9-22)12-13-32-14-16-33(17-15-32)28-24-4-2-3-5-26(24)37-30-28/h2-5,10-11,18-20,22,31H,6-9,12-17H2/t20-,22- OJONWBFOVMXDLK-AQYVVDRMSA-N 263402 US9550741, II-12 D(2) dopamine receptor Homo sapiens 8.82 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263402&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135120970 377002309 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499480 Cc1ccc2sc(cc2c1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C28H34N4O2S3/c1-20-6-11-25-22(18-20)19-27(35-25)37(33,34)30-23-9-7-21(8-10-23)12-13-31-14-16-32(17-15-31)28-24-4-2-3-5-26(24)36-29-28/h2-6,11,18-19,21,23,30H,7-10,12-17H2,1H3/t21-,23- KADPHBZQZJDCJN-AFARHQOCSA-N 263403 US9550741, II-13 D(2) dopamine receptor Homo sapiens 4.50 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263403&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342406 377002310 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499483 O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1 InChI=1S/C23H30N4O2S3/c28-32(29,22-6-3-17-30-22)25-19-9-7-18(8-10-19)11-12-26-13-15-27(16-14-26)23-20-4-1-2-5-21(20)31-24-23/h1-6,17-19,25H,7-16H2/t18-,19+ UCRMCTXHTPNGTQ-KDURUIRLSA-N 263411 US9550741, II-16 D(2) dopamine receptor Homo sapiens 1.75 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263411&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342294 377002315 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499484 O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccc[nH]1 263412 US9550741, II-17 D(2) dopamine receptor Homo sapiens 2.94 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263412&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342438 377002316 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499485 O=S(=O)(N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccco1 InChI=1S/C23H30N4O3S2/c28-32(29,22-6-3-17-30-22)25-19-9-7-18(8-10-19)11-12-26-13-15-27(16-14-26)23-20-4-1-2-5-21(20)31-24-23/h1-6,17-19,25H,7-16H2/t18-,19+ PPOMMOPYGUOVFS-KDURUIRLSA-N 263413 US9550741, II-18 D(2) dopamine receptor Homo sapiens 1.22 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263413&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342469 377002317 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499491 CCOC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C22H32N4O2S/c1-2-28-22(27)23-18-9-7-17(8-10-18)11-12-25-13-15-26(16-14-25)21-19-5-3-4-6-20(19)29-24-21/h3-6,17-18H,2,7-16H2,1H3,(H,23,27)/t17-,18- BYJLEOXPONSXOY-IYARVYRRSA-N 50207158 CHEMBL3982486::US9550741, III-2 D(2) dopamine receptor Homo sapiens 0.710 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86341962 375981468 CHEMBL3982486 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499492 CC(C)COC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C24H36N4O2S/c1-18(2)17-30-24(29)25-20-9-7-19(8-10-20)11-12-27-13-15-28(16-14-27)23-21-5-3-4-6-22(21)31-26-23/h3-6,18-20H,7-17H2,1-2H3,(H,25,29)/t19-,20- VWHNWZZZFGWTTI-MXVIHJGJSA-N 263421 US9550741, III-3 D(2) dopamine receptor Homo sapiens 8.67 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86341963 377002325 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499494 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)OC1CCCCC1 InChI=1S/C26H38N4O2S/c31-26(32-22-6-2-1-3-7-22)27-21-12-10-20(11-13-21)14-15-29-16-18-30(19-17-29)25-23-8-4-5-9-24(23)33-28-25/h4-5,8-9,20-22H,1-3,6-7,10-19H2,(H,27,31)/t20-,21- VZHORDSFYCKLRO-MEMLXQNLSA-N 263423 US9550741, III-5 D(2) dopamine receptor Homo sapiens 11.8 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263423&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86341965 377002327 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499500 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)OCc1ccccc1 InChI=1S/C27H34N4O2S/c32-27(33-20-22-6-2-1-3-7-22)28-23-12-10-21(11-13-23)14-15-30-16-18-31(19-17-30)26-24-8-4-5-9-25(24)34-29-26/h1-9,21,23H,10-20H2,(H,28,32)/t21-,23- DYERWDPVNLQROR-AFARHQOCSA-N 263429 US9550741, III-11 D(2) dopamine receptor Homo sapiens 1.60 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342027 377002333 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499501 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)OCc1cc2ccccc2o1 InChI=1S/C29H34N4O3S/c34-29(35-20-24-19-22-5-1-3-7-26(22)36-24)30-23-11-9-21(10-12-23)13-14-32-15-17-33(18-16-32)28-25-6-2-4-8-27(25)37-31-28/h1-8,19,21,23H,9-18,20H2,(H,30,34)/t21-,23- SWZJPLIVZNKLDQ-AFARHQOCSA-N 263430 US9550741, III-12 D(2) dopamine receptor Homo sapiens 5.73 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342028 377002334 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499503 COC(=O)N[C@@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C21H30N4O2S/c1-27-21(26)22-17-8-6-16(7-9-17)10-11-24-12-14-25(15-13-24)20-18-4-2-3-5-19(18)28-23-20/h2-5,16-17H,6-15H2,1H3,(H,22,26)/t16-,17+ GJKBMWIJPUSQGX-CALCHBBNSA-N 263432 US9550741, III-14 D(2) dopamine receptor Homo sapiens 2.26 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342030 377002336 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499506 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1ccccc1 InChI=1S/C26H33N5OS/c32-26(27-21-6-2-1-3-7-21)28-22-12-10-20(11-13-22)14-15-30-16-18-31(19-17-30)25-23-8-4-5-9-24(23)33-29-25/h1-9,20,22H,10-19H2,(H2,27,28,32)/t20-,22- LBCLWNAKMLUAKD-AQYVVDRMSA-N 50207162 CHEMBL3918755::US9550741, IV-1 D(2) dopamine receptor Homo sapiens 1.06 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207162&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86341996 375981471 CHEMBL3918755 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499507 O=C(NCCc1ccccc1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1 InChI=1S/C28H37N5OS/c34-28(29-16-14-22-6-2-1-3-7-22)30-24-12-10-23(11-13-24)15-17-32-18-20-33(21-19-32)27-25-8-4-5-9-26(25)35-31-27/h1-9,23-24H,10-21H2,(H2,29,30,34)/t23-,24- QPVGNXJYLPJOIQ-RQNOJGIXSA-N 263436 US9550741, IV-2 D(2) dopamine receptor Homo sapiens 9.15 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342060 377002340 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499508 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1cccnc1 InChI=1S/C25H32N6OS/c32-25(28-21-4-3-12-26-18-21)27-20-9-7-19(8-10-20)11-13-30-14-16-31(17-15-30)24-22-5-1-2-6-23(22)33-29-24/h1-6,12,18-20H,7-11,13-17H2,(H2,27,28,32)/t19-,20- DBRVEHQLZZEVFX-MXVIHJGJSA-N 50207113 CHEMBL3896937::US9550741, IV-3 D(2) dopamine receptor Homo sapiens 0.880 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207113&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342061 375981445 CHEMBL3896937 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499509 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1ccco1 InChI=1S/C24H31N5O2S/c30-24(26-22-6-3-17-31-22)25-19-9-7-18(8-10-19)11-12-28-13-15-29(16-14-28)23-20-4-1-2-5-21(20)32-27-23/h1-6,17-19H,7-16H2,(H2,25,26,30)/t18-,19- APCSKDZXHMFZBO-WGSAOQKQSA-N 263438 US9550741, IV-4 D(2) dopamine receptor Homo sapiens 0.800 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342062 377002342 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499510 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)Nc1cc2ccccc2s1 InChI=1S/C28H33N5OS2/c34-28(30-26-19-21-5-1-3-7-24(21)35-26)29-22-11-9-20(10-12-22)13-14-32-15-17-33(18-16-32)27-23-6-2-4-8-25(23)36-31-27/h1-8,19-20,22H,9-18H2,(H2,29,30,34)/t20-,22- QVVUXZWJNUQUIQ-AQYVVDRMSA-N 263439 US9550741, IV-5 D(2) dopamine receptor Homo sapiens 6.77 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342063 377002343 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499513 CN(C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1cccs1 InChI=1S/C25H33N5OS2/c1-28(23-7-4-18-32-23)25(31)26-20-10-8-19(9-11-20)12-13-29-14-16-30(17-15-29)24-21-5-2-3-6-22(21)33-27-24/h2-7,18-20H,8-17H2,1H3,(H,26,31)/t19-,20- XMADFSDPKTZGLY-MXVIHJGJSA-N 263442 US9550741, IV-8 D(2) dopamine receptor Homo sapiens 0.920 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342059 377002346 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499514 COc1cccc(NC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nsc4ccccc34)CC2)c1 InChI=1S/C27H35N5O2S/c1-34-23-6-4-5-22(19-23)29-27(33)28-21-11-9-20(10-12-21)13-14-31-15-17-32(18-16-31)26-24-7-2-3-8-25(24)35-30-26/h2-8,19-21H,9-18H2,1H3,(H2,28,29,33)/t20-,21- YRESHCJSCNXCIP-MEMLXQNLSA-N 263443 US9550741, IV-9 D(2) dopamine receptor Homo sapiens 3.01 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342096 377002347 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 499515 [O-][N+](=O)c1cccc(NC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nsc4ccccc34)CC2)c1 InChI=1S/C26H32N6O3S/c33-26(28-21-4-3-5-22(18-21)32(34)35)27-20-10-8-19(9-11-20)12-13-30-14-16-31(17-15-30)25-23-6-1-2-7-24(23)36-29-25/h1-7,18-20H,8-17H2,(H2,27,28,33)/t19-,20- ULGYNCVBFLQVPX-MXVIHJGJSA-N 263444 US9550741, IV-10 D(2) dopamine receptor Homo sapiens 3.64 7.5 US Patent 10.7270/Q2DN4726 aid1795236 US9550741 Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Shanghai Institute of Pharmaceutical Industry http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=263444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=263444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86342097 377002348 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50111193 COc1ccc(cc1)N1CCN(CC[C@@H]2OCCc3cc(ccc23)C(N)=O)CC1 InChI=1S/C23H29N3O3/c1-28-20-5-3-19(4-6-20)26-13-11-25(12-14-26)10-8-22-21-7-2-18(23(24)27)16-17(21)9-15-29-22/h2-7,16,22H,8-15H2,1H3,(H2,24,27)/t22-/m0/s1 OCFFXDBBLHVFSW-QFIPXVFZSA-N 50064784 (S)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL71635 D(2) dopamine receptor Homo sapiens 325 ChEMBL 10.1021/jm980137o 10.7270/Q2NV9HCP 9632349 Ennis, MD; Ghazal, NB; Hoffman, RL; Smith, MW; Schlachter, SK; Lawson, CF; Im, WB; Pregenzer, JF; Svensson, KA; Lewis, RA; Hall, ED; Sutter, DM; Harris, LT; McCall, RB Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620719 103959740 CHEMBL71635 ZINC13779784 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50111196 COc1ccc(cc1)N1CCN(CCC2OCCc3cc(ccc23)C(N)=O)CC1 InChI=1S/C23H29N3O3/c1-28-20-5-3-19(4-6-20)26-13-11-25(12-14-26)10-8-22-21-7-2-18(23(24)27)16-17(21)9-15-29-22/h2-7,16,22H,8-15H2,1H3,(H2,24,27) OCFFXDBBLHVFSW-UHFFFAOYSA-N 50064785 1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL69385 D(2) dopamine receptor Homo sapiens 348 ChEMBL 10.1021/jm980137o 10.7270/Q2NV9HCP 9632349 Ennis, MD; Ghazal, NB; Hoffman, RL; Smith, MW; Schlachter, SK; Lawson, CF; Im, WB; Pregenzer, JF; Svensson, KA; Lewis, RA; Hall, ED; Sutter, DM; Harris, LT; McCall, RB Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23288790 103959741 CHEMBL69385 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50111201 COc1ccc(cc1)N1CCN(CC[C@H]2OCCc3cc(ccc23)C(N)=O)CC1 InChI=1S/C23H29N3O3/c1-28-20-5-3-19(4-6-20)26-13-11-25(12-14-26)10-8-22-21-7-2-18(23(24)27)16-17(21)9-15-29-22/h2-7,16,22H,8-15H2,1H3,(H2,24,27)/t22-/m1/s1 OCFFXDBBLHVFSW-JOCHJYFZSA-N 50064783 (R)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL71907 D(2) dopamine receptor Homo sapiens 386 ChEMBL 10.1021/jm980137o 10.7270/Q2NV9HCP 9632349 Ennis, MD; Ghazal, NB; Hoffman, RL; Smith, MW; Schlachter, SK; Lawson, CF; Im, WB; Pregenzer, JF; Svensson, KA; Lewis, RA; Hall, ED; Sutter, DM; Harris, LT; McCall, RB Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064783&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692095 103959739 CHEMBL71907 ZINC13779785 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50111204 CNC(=O)c1ccc2[C@H](CCN3CCN(CC3)c3ccc(OC)cc3)OCCc2c1 InChI=1S/C24H31N3O3/c1-25-24(28)19-3-8-22-18(17-19)10-16-30-23(22)9-11-26-12-14-27(15-13-26)20-4-6-21(29-2)7-5-20/h3-8,17,23H,9-16H2,1-2H3,(H,25,28)/t23-/m0/s1 UDLSEQDYARNKTL-QHCPKHFHSA-N 50064786 (S)-1-(2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-N-methyl-3,4-dihydro-1H-isochromene-6-carboxamide::(S)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid methylamide::CHEMBL71838 D(2) dopamine receptor Homo sapiens 241 ChEMBL 10.1021/jm980137o 10.7270/Q2NV9HCP 9632349 Ennis, MD; Ghazal, NB; Hoffman, RL; Smith, MW; Schlachter, SK; Lawson, CF; Im, WB; Pregenzer, JF; Svensson, KA; Lewis, RA; Hall, ED; Sutter, DM; Harris, LT; McCall, RB Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9909448 103959742 CHEMBL71838 3228 ZINC03828610 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50111207 CNC(=O)c1ccc2[C@@H](CCN3CCN(CC3)c3ccc(OC)cc3)OCCc2c1 InChI=1S/C24H31N3O3/c1-25-24(28)19-3-8-22-18(17-19)10-16-30-23(22)9-11-26-12-14-27(15-13-26)20-4-6-21(29-2)7-5-20/h3-8,17,23H,9-16H2,1-2H3,(H,25,28)/t23-/m1/s1 UDLSEQDYARNKTL-HSZRJFAPSA-N 50064787 (R)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid methylamide::CHEMBL71798 D(2) dopamine receptor Homo sapiens 158 ChEMBL 10.1021/jm980137o 10.7270/Q2NV9HCP 9632349 Ennis, MD; Ghazal, NB; Hoffman, RL; Smith, MW; Schlachter, SK; Lawson, CF; Im, WB; Pregenzer, JF; Svensson, KA; Lewis, RA; Hall, ED; Sutter, DM; Harris, LT; McCall, RB Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064787&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10621491 103959743 CHEMBL71798 ZINC13779786 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50111219 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax D(2) dopamine receptor Homo sapiens >218 ChEMBL 10.1021/jm980137o 10.7270/Q2NV9HCP 9632349 Ennis, MD; Ghazal, NB; Hoffman, RL; Smith, MW; Schlachter, SK; Lawson, CF; Im, WB; Pregenzer, JF; Svensson, KA; Lewis, RA; Hall, ED; Sutter, DM; Harris, LT; McCall, RB Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50111228 COc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1 InChI=1S/C22H28N2O2/c1-25-20-8-6-19(7-9-20)24-15-13-23(14-16-24)12-10-22-21-5-3-2-4-18(21)11-17-26-22/h2-9,22H,10-17H2,1H3 IAUNACXRZSWWJT-UHFFFAOYSA-N 50051562 1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-piperazine::CHEMBL71724 D(2) dopamine receptor Homo sapiens 1431 ChEMBL 10.1021/jm980137o 10.7270/Q2NV9HCP 9632349 Ennis, MD; Ghazal, NB; Hoffman, RL; Smith, MW; Schlachter, SK; Lawson, CF; Im, WB; Pregenzer, JF; Svensson, KA; Lewis, RA; Hall, ED; Sutter, DM; Harris, LT; McCall, RB Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9863333 103948557 CHEMBL71724 ZINC03812551 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117809 COc1cccc(c1)C(=O)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C21H27N3O3/c1-26-18-7-5-6-17(16-18)21(25)22-10-11-23-12-14-24(15-13-23)19-8-3-4-9-20(19)27-2/h3-9,16H,10-15H2,1-2H3,(H,22,25) LXCQKNOPMINDBU-UHFFFAOYSA-N 50068362 3-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL286725 D(2) dopamine receptor Homo sapiens 700 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068362&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406796 103962608 CHEMBL286725 ZINC53084608 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117810 Cl.COc1cccc(c1)-c1csc(CCN2CCN(CC2)c2ccccc2OC)n1 InChI=1S/C23H27N3O2S.ClH/c1-27-19-7-5-6-18(16-19)20-17-29-23(24-20)10-11-25-12-14-26(15-13-25)21-8-3-4-9-22(21)28-2;/h3-9,16-17H,10-15H2,1-2H3;1H BBXFSMRJSWMPQM-UHFFFAOYSA-N 50068375 1-(2-Methoxy-phenyl)-4-{2-[4-(3-methoxy-phenyl)-thiazol-2-yl]-ethyl}-piperazine::CHEMBL2373205 D(2) dopamine receptor Homo sapiens 870 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350334 103962621 CHEMBL2373205 ZINC13782144 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117811 COc1ccc(OC)c(c1)C(=O)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C22H29N3O4/c1-27-17-8-9-20(28-2)18(16-17)22(26)23-10-11-24-12-14-25(15-13-24)19-6-4-5-7-21(19)29-3/h4-9,16H,10-15H2,1-3H3,(H,23,26) CLHNMTROPPBBIR-UHFFFAOYSA-N 50068377 2,5-Dimethoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL144811 D(2) dopamine receptor Homo sapiens 250 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10501113 103962623 CHEMBL144811 ZINC13782140 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117813 COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2)CC1 InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-11-12-25(18-19)20-7-3-2-4-8-20/h2-12,18H,13-17H2,1H3 UPXJKNQVKALXKP-UHFFFAOYSA-N 50048233 1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmethyl)-piperazine::CHEMBL28321 D(2) dopamine receptor Homo sapiens 1.3 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048233&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10450375 103978759 CHEMBL28321 ZINC13744963 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117818 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OGJGQVFWEPNYSB-UHFFFAOYSA-N 85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853 D(2) dopamine receptor Homo sapiens 920 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L74 6IQL 5311200 136351193 CHEMBL555670CHEMBL267014 3303 ZINC25760037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117770 COc1ccccc1N1CCN(CCNC(=O)c2ccccc2OC)CC1 InChI=1S/C21H27N3O3/c1-26-19-9-5-3-7-17(19)21(25)22-11-12-23-13-15-24(16-14-23)18-8-4-6-10-20(18)27-2/h3-10H,11-16H2,1-2H3,(H,22,25) LELUFGKRDMZHEF-UHFFFAOYSA-N 50068361 2-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL356358 D(2) dopamine receptor Homo sapiens 810 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068361&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10832895 103962607 CHEMBL356358 ZINC53106866 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117771 Cl.Cl.COc1ccc2CCC(Cc2c1)NC(=O)CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3.2ClH/c1-30-22-10-8-19-7-9-21(17-20(19)18-22)26-25(29)11-12-27-13-15-28(16-14-27)23-5-3-4-6-24(23)31-2;;/h3-6,8,10,18,21H,7,9,11-17H2,1-2H3,(H,26,29);2*1H XHIAWXRTGOFODI-UHFFFAOYSA-N 50068363 3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide::CHEMBL2373210 D(2) dopamine receptor Homo sapiens 30.0 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068363&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354845 103962609 CHEMBL2373210 ZINC27555391 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117774 COc1ccc2CCCC(CCCN3CCN(CC3)c3ccccc3OC)c2c1 InChI=1S/C25H34N2O2/c1-28-22-13-12-21-8-5-7-20(23(21)19-22)9-6-14-26-15-17-27(18-16-26)24-10-3-4-11-25(24)29-2/h3-4,10-13,19-20H,5-9,14-18H2,1-2H3 CCYRVZGWDNSBAQ-UHFFFAOYSA-N 50033858 1-(2-Methoxy-phenyl)-4-[3-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL424125 D(2) dopamine receptor Homo sapiens 150 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10092041 103942106 CHEMBL424125 ZINC13740672 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117775 COc1cccc(c1)C(=O)CCCN1CCN(CC1)c1ccccc1OC InChI=1S/C22H28N2O3/c1-26-19-8-5-7-18(17-19)21(25)10-6-12-23-13-15-24(16-14-23)20-9-3-4-11-22(20)27-2/h3-5,7-9,11,17H,6,10,12-16H2,1-2H3 XGXUWJSIDSMGFX-UHFFFAOYSA-N 50068364 1-(3-Methoxy-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one::CHEMBL26677 D(2) dopamine receptor Homo sapiens 13 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11726532 103962610 CHEMBL26677 ZINC13493235 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117776 COc1ccccc1N1CCN(CCNC2=Nc3ccccc3OC2)CC1 InChI=1S/C21H26N4O2/c1-26-20-9-5-3-7-18(20)25-14-12-24(13-15-25)11-10-22-21-16-27-19-8-4-2-6-17(19)23-21/h2-9H,10-16H2,1H3,(H,22,23) CLSKBBHRGMBREO-UHFFFAOYSA-N 50068365 (2H-Benzo[1,4]oxazin-3-yl)-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amine::CHEMBL148024 D(2) dopamine receptor Homo sapiens 280 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068365&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44363725 103962611 CHEMBL148024 ZINC12356212 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117777 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C25H34N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,10,12-14,20H,5,7-9,11,15-19H2,1-2H3 INGWKGCHJJYQIB-UHFFFAOYSA-N 50033839 1-(2-Methoxy-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL26929 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10385977 103942087 CHEMBL26929 ZINC13740674 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117781 CCC(C)(C)C(=O)NCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C18H28ClN3O/c1-4-18(2,3)17(23)20-9-10-21-11-13-22(14-12-21)16-7-5-15(19)6-8-16/h5-8H,4,9-14H2,1-3H3,(H,20,23) XIGWRMXCBASJKN-UHFFFAOYSA-N 50068367 CHEMBL283353::N-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-2,2-dimethyl-butyramide D(2) dopamine receptor Homo sapiens 2519 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068367&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10359736 103962613 CHEMBL283353 ZINC13782139 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117784 COc1cccc(c1)C(=O)NCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C20H24ClN3O2/c1-26-19-4-2-3-16(15-19)20(25)22-9-10-23-11-13-24(14-12-23)18-7-5-17(21)6-8-18/h2-8,15H,9-14H2,1H3,(H,22,25) DQVARXSGNFBPMB-UHFFFAOYSA-N 50068366 CHEMBL93403::N-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3-methoxy-benzamide D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3626837 103962612 CHEMBL93403 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117785 O.Cl.Cl.Cl.COc1cccc(c1)-c1csc(CN2CCN(CC2)c2ccccc2OC)n1 InChI=1S/C22H25N3O2S.3ClH.H2O/c1-26-18-7-5-6-17(14-18)19-16-28-22(23-19)15-24-10-12-25(13-11-24)20-8-3-4-9-21(20)27-2;;;;/h3-9,14,16H,10-13,15H2,1-2H3;3*1H;1H2 XWFKCVKPDWYFKY-UHFFFAOYSA-N 50068370 1-(2-Methoxy-phenyl)-4-[4-(3-methoxy-phenyl)-thiazol-2-ylmethyl]-piperazine::CHEMBL2373206 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068370&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354844 103962616 CHEMBL2373206 ZINC13782143 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117790 O.Cl.Cl.COc1cccc(c1)C(=O)NCCN1CCN(Cc2ccccc2OC)CC1 InChI=1S/C22H29N3O3.2ClH.H2O/c1-27-20-8-5-7-18(16-20)22(26)23-10-11-24-12-14-25(15-13-24)17-19-6-3-4-9-21(19)28-2;;;/h3-9,16H,10-15,17H2,1-2H3,(H,23,26);2*1H;1H2 GNKVPVNTTHKDOL-UHFFFAOYSA-N 50068373 3-Methoxy-N-{2-[4-(2-methoxy-benzyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL2373204 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068373&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356382 103962619 CHEMBL2373204 ZINC22939115 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117794 COc1cccc2CC(CCc12)NC(=O)CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3/c1-30-23-9-5-6-19-18-20(10-11-21(19)23)26-25(29)12-13-27-14-16-28(17-15-27)22-7-3-4-8-24(22)31-2/h3-9,20H,10-18H2,1-2H3,(H,26,29) KLUQJNMZPFJSGW-UHFFFAOYSA-N 50068371 3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide::CHEMBL359002 D(2) dopamine receptor Homo sapiens 761 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068371&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44363755 103962617 CHEMBL359002 ZINC27555889 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117795 COc1cccc(c1)C(=O)NCCCN1CCN(CC1)c1ccccc1OC InChI=1S/C22H29N3O3/c1-27-19-8-5-7-18(17-19)22(26)23-11-6-12-24-13-15-25(16-14-24)20-9-3-4-10-21(20)28-2/h3-5,7-10,17H,6,11-16H2,1-2H3,(H,23,26) KTPQCLNOFMRFDQ-UHFFFAOYSA-N 50068374 3-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzamide::CHEMBL357448 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643697 103962620 CHEMBL357448 ZINC11909366 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117797 COc1cccc(c1)C(=O)NCCN1CCN(CC1)c1ccccn1 InChI=1S/C19H24N4O2/c1-25-17-6-4-5-16(15-17)19(24)21-9-10-22-11-13-23(14-12-22)18-7-2-3-8-20-18/h2-8,15H,9-14H2,1H3,(H,21,24) RMGWJLOIEDIFJI-UHFFFAOYSA-N 50068369 3-Methoxy-N-[2-(4-pyridin-2-yl-piperazin-1-yl)-ethyl]-benzamide::CHEMBL147483 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783358 103962615 CHEMBL147483 ZINC13492648 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117798 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 230 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117800 O.Cl.Cl.COc1cccc(c1)C(=O)NCCN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C21H26ClN3O2.2ClH.H2O/c1-27-20-4-2-3-18(15-20)21(26)23-9-10-24-11-13-25(14-12-24)16-17-5-7-19(22)8-6-17;;;/h2-8,15H,9-14,16H2,1H3,(H,23,26);2*1H;1H2 BOCDEVXEPQZDGU-UHFFFAOYSA-N 50068368 CHEMBL2373207::N-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethyl}-3-methoxy-benzamide D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350335 103962614 CHEMBL2373207 ZINC22939118 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50117805 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 4.1 ChEMBL 10.1021/jm981041x 10.7270/Q2S46R3V 9822559 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119088 Fc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ccc(Cl)cn2)cc1 InChI=1S/C20H23ClFN3O/c21-16-2-8-20(23-11-16)25-10-9-24-12-15(1-5-18(24)13-25)14-26-19-6-3-17(22)4-7-19/h2-4,6-8,11,15,18H,1,5,9-10,12-14H2/t15-,18+/m1/s1 DDLMXDXJVCLTCF-QAPCUYQASA-N 50069034 (7R,9aS)-2-(5-Chloro-pyridin-2-yl)-7-(4-fluoro-phenoxymethyl)-octahydro-pyrido[1,2-a]pyrazine::CHEMBL161982 D(2) dopamine receptor Homo sapiens 1880 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9821010 103963180 CHEMBL161982 ZINC27851520 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119089 C(Oc1ccccc1)[C@@H]1CC[C@H]2CN(CCN2C1)c1ccccc1 InChI=1S/C21H26N2O/c1-3-7-19(8-4-1)23-14-13-22-15-18(11-12-20(22)16-23)17-24-21-9-5-2-6-10-21/h1-10,18,20H,11-17H2/t18-,20+/m1/s1 KATJMALRFZLGNX-QUCCMNQESA-N 50069035 (7R,9aS)-7-Phenoxymethyl-2-phenyl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL351611 D(2) dopamine receptor Homo sapiens 44 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376876 103963181 CHEMBL351611 ZINC53092474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119090 C(Oc1ccccc1)[C@@H]1CC[C@H]2CN(CCN2C1)c1ccccn1 InChI=1S/C20H25N3O/c1-2-6-19(7-3-1)24-16-17-9-10-18-15-23(13-12-22(18)14-17)20-8-4-5-11-21-20/h1-8,11,17-18H,9-10,12-16H2/t17-,18+/m1/s1 CFDPQJPZOGBUMP-MSOLQXFVSA-N 50069037 (7R,9aS)-7-Phenoxymethyl-2-pyridin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL350160 D(2) dopamine receptor Homo sapiens 187 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376918 103963183 CHEMBL350160 ZINC27854008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119091 C(Oc1ccccc1)C1CCC2CN(CCN2C1)c1ncccn1 InChI=1S/C19H24N4O/c1-2-5-18(6-3-1)24-15-16-7-8-17-14-23(12-11-22(17)13-16)19-20-9-4-10-21-19/h1-6,9-10,16-17H,7-8,11-15H2 IAMSHZCIGNPBQZ-UHFFFAOYSA-N 50069038 7-Phenoxymethyl-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL162265 D(2) dopamine receptor Homo sapiens 185 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21997225 103963184 CHEMBL162265 ZINC36216603 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119093 Fc1ccc(OC[C@H]2CC[C@H]3CN(CCN3C2)c2ncc(F)cn2)cc1 InChI=1S/C19H22F2N4O/c20-15-2-5-18(6-3-15)26-13-14-1-4-17-12-25(8-7-24(17)11-14)19-22-9-16(21)10-23-19/h2-3,5-6,9-10,14,17H,1,4,7-8,11-13H2/t14-,17-/m0/s1 QXWNESOGWFJDFR-YOEHRIQHSA-N 50069039 (7S,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine::CHEMBL163009 D(2) dopamine receptor Homo sapiens 68 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376209 103963185 CHEMBL163009 ZINC27844951 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119094 C(Oc1ccccc1)[C@H]1CC[C@H]2CN(CCN2C1)c1ncccn1 InChI=1S/C19H24N4O/c1-2-5-18(6-3-1)24-15-16-7-8-17-14-23(12-11-22(17)13-16)19-20-9-4-10-21-19/h1-6,9-10,16-17H,7-8,11-15H2/t16-,17-/m0/s1 IAMSHZCIGNPBQZ-IRXDYDNUSA-N 50069036 (7S,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL165504 D(2) dopamine receptor Homo sapiens 38 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376569 103963182 CHEMBL165504 ZINC27858693 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119095 CC(=O)Nc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ncccn2)cc1 InChI=1S/C21H27N5O2/c1-16(27)24-18-4-7-20(8-5-18)28-15-17-3-6-19-14-26(12-11-25(19)13-17)21-22-9-2-10-23-21/h2,4-5,7-10,17,19H,3,6,11-15H2,1H3,(H,24,27)/t17-,19+/m1/s1 CWRQNZXCKKVFTG-MJGOQNOKSA-N 50069040 CHEMBL161899::N-[4-((7R,9aS)-2-Pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazin-7-ylmethoxy)-phenyl]-acetamide D(2) dopamine receptor Homo sapiens 948.0 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069040&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376920 103963186 CHEMBL161899 ZINC27854027 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119099 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.840000 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119104 Fc1ccc(OC[C@H]2CC[C@@H]3CN(CCN3C2)c2ncc(F)cn2)cc1 InChI=1S/C19H22F2N4O/c20-15-2-5-18(6-3-15)26-13-14-1-4-17-12-25(8-7-24(17)11-14)19-22-9-16(21)10-23-19/h2-3,5-6,9-10,14,17H,1,4,7-8,11-13H2/t14-,17+/m0/s1 QXWNESOGWFJDFR-WMLDXEAASA-N 50069045 (7S,9aR)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine::CHEMBL162873 D(2) dopamine receptor Homo sapiens 195 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9885219 103963191 CHEMBL162873 ZINC00601673 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119106 Fc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ncc(F)cn2)cc1 InChI=1S/C19H22F2N4O/c20-15-2-5-18(6-3-15)26-13-14-1-4-17-12-25(8-7-24(17)11-14)19-22-9-16(21)10-23-19/h2-3,5-6,9-10,14,17H,1,4,7-8,11-13H2/t14-,17+/m1/s1 QXWNESOGWFJDFR-PBHICJAKSA-N 50069041 (7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine::7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine (CP-293019)::CHEMBL66227::CP-293019 D(2) dopamine receptor Homo sapiens >3310 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820261 103963187 CHEMBL66227 977 ZINC03825236 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119107 Fc1ccc(OC[C@@H]2CC[C@@H]3CN(CCN3C2)c2ncc(F)cn2)cc1 InChI=1S/C19H22F2N4O/c20-15-2-5-18(6-3-15)26-13-14-1-4-17-12-25(8-7-24(17)11-14)19-22-9-16(21)10-23-19/h2-3,5-6,9-10,14,17H,1,4,7-8,11-13H2/t14-,17-/m1/s1 QXWNESOGWFJDFR-RHSMWYFYSA-N 50069044 (7R,9aR)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine::CHEMBL349699 D(2) dopamine receptor Homo sapiens 980 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906895 103963190 CHEMBL349699 ZINC27851346 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119108 COC(=O)c1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ncccn2)cc1 InChI=1S/C21H26N4O3/c1-27-20(26)17-4-7-19(8-5-17)28-15-16-3-6-18-14-25(12-11-24(18)13-16)21-22-9-2-10-23-21/h2,4-5,7-10,16,18H,3,6,11-15H2,1H3/t16-,18+/m1/s1 XAVXJXMGRFXIFC-AEFFLSMTSA-N 50069046 4-((7R,9aS)-2-Pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazin-7-ylmethoxy)-benzoic acid methyl ester::CHEMBL165113 D(2) dopamine receptor Homo sapiens 254 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376921 103963192 CHEMBL165113 ZINC27857726 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119111 Fc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ccc(F)cc2)cc1 InChI=1S/C21H24F2N2O/c22-17-2-7-19(8-3-17)25-12-11-24-13-16(1-6-20(24)14-25)15-26-21-9-4-18(23)5-10-21/h2-5,7-10,16,20H,1,6,11-15H2/t16-,20+/m1/s1 YBGMRLZOHGQJTB-UZLBHIALSA-N 50069042 (7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(4-fluoro-phenyl)-octahydro-pyrido[1,2-a]pyrazine::CHEMBL166321 D(2) dopamine receptor Homo sapiens 206 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069042&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10133031 103963188 CHEMBL166321 ZINC53275877 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119112 COc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ncccn2)cc1 InChI=1S/C20H26N4O2/c1-25-18-5-7-19(8-6-18)26-15-16-3-4-17-14-24(12-11-23(17)13-16)20-21-9-2-10-22-20/h2,5-10,16-17H,3-4,11-15H2,1H3/t16-,17+/m1/s1 DJHHAPHHUCKKIN-SJORKVTESA-N 50069043 (7R,9aS)-7-(4-Methoxy-phenoxymethyl)-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL351098 D(2) dopamine receptor Homo sapiens 918 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376241 103963189 CHEMBL351098 ZINC27764744 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119118 Fc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ncccn2)cc1 InChI=1S/C19H23FN4O/c20-16-3-6-18(7-4-16)25-14-15-2-5-17-13-24(11-10-23(17)12-15)19-21-8-1-9-22-19/h1,3-4,6-9,15,17H,2,5,10-14H2/t15-,17+/m1/s1 UHFPHCOQBXQSQQ-WBVHZDCISA-N 50069048 (7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL159903 D(2) dopamine receptor Homo sapiens 1196 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15512070 103963194 CHEMBL159903 ZINC27764751 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119122 C(Oc1ccccc1)[C@@H]1CC[C@H]2CN(CCN2C1)c1ncccn1 InChI=1S/C19H24N4O/c1-2-5-18(6-3-1)24-15-16-7-8-17-14-23(12-11-22(17)13-16)19-20-9-4-10-21-19/h1-6,9-10,16-17H,7-8,11-15H2/t16-,17+/m1/s1 IAMSHZCIGNPBQZ-SJORKVTESA-N 50069047 (7R,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL166269 D(2) dopamine receptor Homo sapiens 1140 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15817410 103963193 CHEMBL166269 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119126 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 155 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50119128 CC(C)(C)c1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ncccn2)cc1 InChI=1S/C23H32N4O/c1-23(2,3)19-6-9-21(10-7-19)28-17-18-5-8-20-16-27(14-13-26(20)15-18)22-24-11-4-12-25-22/h4,6-7,9-12,18,20H,5,8,13-17H2,1-3H3/t18-,20+/m1/s1 GSVGUZSCTGJZJV-QUCCMNQESA-N 50069049 (7R,9aS)-7-(4-tert-Butyl-phenoxymethyl)-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL349904 D(2) dopamine receptor Homo sapiens 1720 ChEMBL 10.1016/s0960-894x(98)00108-5 10.7270/Q29Z941K 9871530 Sanner, MA; Chappie, TA; Dunaiskis, AR; Fliri, AF; Desai, KA; Zorn, SH; Jackson, ER; Johnson, CG; Morrone, JM; Seymour, PA; Majchrzak, MJ; Faraci, WS; Collins, JL; Duignan, DB; Prete Di, CC; Lee, JS; Trozzi, A Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376230 103963195 CHEMBL349904 ZINC27853698 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120570 Oc1ccccc1OCCNCc1ccccc1 InChI=1S/C15H17NO2/c17-14-8-4-5-9-15(14)18-11-10-16-12-13-6-2-1-3-7-13/h1-9,16-17H,10-12H2 VNAZBTWTBGIYND-UHFFFAOYSA-N 50069906 2-(2-Benzylamino-ethoxy)-phenol::CHEMBL101285 D(2) dopamine receptor Homo sapiens 456.0 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069906&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332581 103963868 CHEMBL101285 ZINC26750210 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120573 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Homo sapiens 246 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120579 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Homo sapiens 10 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120587 CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1Cl InChI=1S/C14H17ClN2O3S2/c1-22(18,19)17-14-9-11(4-5-13(14)15)20-7-6-16-10-12-3-2-8-21-12/h2-5,8-9,16-17H,6-7,10H2,1H3 RGVJFPMOLSXLGJ-UHFFFAOYSA-N 50069908 CHEMBL102490::N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-phenyl)-methanesulfonamide D(2) dopamine receptor Homo sapiens 9 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069908&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332701 103963870 CHEMBL102490 ZINC26823792 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120594 Nc1cc(OCCNCc2ccccc2)ccc1Cl InChI=1S/C15H17ClN2O/c16-14-7-6-13(10-15(14)17)19-9-8-18-11-12-4-2-1-3-5-12/h1-7,10,18H,8-9,11,17H2 MSJYXZAZPCPYHS-UHFFFAOYSA-N 50069920 5-(2-Benzylamino-ethoxy)-2-chloro-phenylamine::CHEMBL319816 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332566 103963882 CHEMBL319816 ZINC26752285 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120599 Oc1ccc2OC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H17NO3/c18-13-6-7-15-16(8-13)20-14(11-19-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-18H,9-11H2/t14-/m0/s1 DYWYWIOQKKRAST-AWEZNQCLSA-N 50061642 (S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid::CHEMBL300571::CHEMBL423890 D(2) dopamine receptor Homo sapiens 7.2 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10612157 103957192 CHEMBL300571CHEMBL423890 ZINC13775979 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120600 C(COc1ccccc1)NCc1ccccc1 InChI=1S/C15H17NO/c1-3-7-14(8-4-1)13-16-11-12-17-15-9-5-2-6-10-15/h1-10,16H,11-13H2 XTNXLNGNJZRBRW-UHFFFAOYSA-N 50069917 Benzyl-(2-phenoxy-ethyl)-amine::CHEMBL103951 D(2) dopamine receptor Homo sapiens >300 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20256387 103963879 CHEMBL103951 ZINC26816095 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120603 Oc1ccc(OCCNCc2ccccc2)cc1 InChI=1S/C15H17NO2/c17-14-6-8-15(9-7-14)18-11-10-16-12-13-4-2-1-3-5-13/h1-9,16-17H,10-12H2 JADOYZZQMNOBML-UHFFFAOYSA-N 50069909 4-(2-Benzylamino-ethoxy)-phenol::CHEMBL100461 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069909&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15034333 103963871 CHEMBL100461 ZINC26751661 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120611 CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F InChI=1S/C16H19FN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3 HEHPXIHFYMLODY-UHFFFAOYSA-N 50069912 CHEMBL323118::N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-methanesulfonamide D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332646 103963874 CHEMBL323118 ZINC26743453 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120614 CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C16H20N2O3S/c1-22(19,20)18-15-8-5-9-16(12-15)21-11-10-17-13-14-6-3-2-4-7-14/h2-9,12,17-18H,10-11,13H2,1H3 ZMVMIDCCNZYMFG-UHFFFAOYSA-N 50069918 CHEMBL99849::N-[3-(2-Benzylamino-ethoxy)-phenyl]-methanesulfonamide D(2) dopamine receptor Homo sapiens 38 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332686 103963880 CHEMBL99849 ZINC26752574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120622 Oc1ccccc1N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-9-5-4-8-16(17)19-12-10-18(11-13-19)14-15-6-2-1-3-7-15/h1-9,20H,10-14H2 FPVKDWNGSLXDRY-UHFFFAOYSA-N 50069916 2-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL100952 D(2) dopamine receptor Homo sapiens >300 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069916&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8529065 103963878 CHEMBL100952 ZINC53165591 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120623 CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1Cl InChI=1S/C16H19ClN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3 GJAYJBGLRYDTKW-UHFFFAOYSA-N 50069921 CHEMBL99913::N-[5-(2-Benzylamino-ethoxy)-2-chloro-phenyl]-methanesulfonamide D(2) dopamine receptor Homo sapiens 76 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332565 103963883 CHEMBL99913 ZINC26752280 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120632 C(N1CCN(CC1)c1ccccc1)c1ccccc1 InChI=1S/C17H20N2/c1-3-7-16(8-4-1)15-18-11-13-19(14-12-18)17-9-5-2-6-10-17/h1-10H,11-15H2 VEJWDLHOLWGRLH-UHFFFAOYSA-N 50069919 1-Benzyl-4-phenyl-piperazine::CHEMBL101032 D(2) dopamine receptor Homo sapiens >300 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069919&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 511484 103963881 CHEMBL101032 ZINC12629325 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120633 Oc1ccc(cc1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-6-16(7-9-17)19-12-10-18(11-13-19)14-15-4-2-1-3-5-15/h1-9,20H,10-14H2 MKDLAVWJHBTGFQ-UHFFFAOYSA-N 50069910 4-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL103900 D(2) dopamine receptor Homo sapiens >300 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069910&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8690650 103963872 CHEMBL103900 ZINC23466472 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120635 Oc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2 VBTFJGYCISLKEQ-UHFFFAOYSA-N 50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508 D(2) dopamine receptor Homo sapiens 76 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776546 103963876 CHEMBL64508 ZINC12355952 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50120636 CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1F InChI=1S/C14H17FN2O3S2/c1-22(18,19)17-14-9-11(4-5-13(14)15)20-7-6-16-10-12-3-2-8-21-12/h2-5,8-9,16-17H,6-7,10H2,1H3 ORNYDPYZWVONOG-UHFFFAOYSA-N 50069913 CHEMBL101910::N-(2-Fluoro-5-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-phenyl)-methanesulfonamide D(2) dopamine receptor Homo sapiens >300 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069913&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332613 103963875 CHEMBL101910 ZINC26820138 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121719 Cc1ccnc(c1)N1CCN(CCC2NC(=O)c3ccccc23)CC1 InChI=1S/C20H24N4O/c1-15-6-8-21-19(14-15)24-12-10-23(11-13-24)9-7-18-16-4-2-3-5-17(16)20(25)22-18/h2-6,8,14,18H,7,9-13H2,1H3,(H,22,25) DQPPITADMDONIT-UHFFFAOYSA-N 50070509 3-{2-[4-(4-Methyl-pyridin-2-yl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL37638 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283941 103964370 CHEMBL37638 ZINC29306184 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121722 O=C1NC(CCN2CCN(CC2)c2ccc3ccccc3c2)c2ccccc12 InChI=1S/C24H25N3O/c28-24-22-8-4-3-7-21(22)23(25-24)11-12-26-13-15-27(16-14-26)20-10-9-18-5-1-2-6-19(18)17-20/h1-10,17,23H,11-16H2,(H,25,28) GNYXSGLNCOUDJV-UHFFFAOYSA-N 50070512 3-[2-(4-Naphthalen-2-yl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one::CHEMBL37169 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9907461 103964373 CHEMBL37169 ZINC29307601 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121724 Clc1ccc(cc1)N1CCN(CCC2NC(=O)c3ccccc23)CC1 InChI=1S/C20H22ClN3O/c21-15-5-7-16(8-6-15)24-13-11-23(12-14-24)10-9-19-17-3-1-2-4-18(17)20(25)22-19/h1-8,19H,9-14H2,(H,22,25) QVEVPLLBXFALKP-UHFFFAOYSA-N 50070515 3-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL290351 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9841608 103964376 CHEMBL290351 ZINC29306333 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121733 Cc1ccc(cc1C)N1CCN(CCC2NC(=O)c3ccccc23)CC1 InChI=1S/C22H27N3O/c1-16-7-8-18(15-17(16)2)25-13-11-24(12-14-25)10-9-21-19-5-3-4-6-20(19)22(26)23-21/h3-8,15,21H,9-14H2,1-2H3,(H,23,26) WQEPZBNLBWDIRZ-UHFFFAOYSA-N 50070517 3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL38262 D(2) dopamine receptor Homo sapiens 1842 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search RMZ 7AMJ 9819770 103964378 CHEMBL38262 ZINC04632541 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121740 COc1ccc(cc1)N1CCN(CCC2NC(=O)c3ccccc23)CC1 InChI=1S/C21H25N3O2/c1-26-17-8-6-16(7-9-17)24-14-12-23(13-15-24)11-10-20-18-4-2-3-5-19(18)21(25)22-20/h2-9,20H,10-15H2,1H3,(H,22,25) WHYWZOSKHMUDHU-UHFFFAOYSA-N 50070511 3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL37706 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906454 103964372 CHEMBL37706 ZINC29310311 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121743 CN1C(CCN2CCN(CC2)c2ccc(Cl)cc2)c2ccccc2C1=O InChI=1S/C21H24ClN3O/c1-23-20(18-4-2-3-5-19(18)21(23)26)10-11-24-12-14-25(15-13-24)17-8-6-16(22)7-9-17/h2-9,20H,10-15H2,1H3 XWNSNFBCWKDIED-UHFFFAOYSA-N 50070516 3-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one::CHEMBL36337 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15888352 103964377 CHEMBL36337 ZINC29243748 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121748 Cc1ccc(cc1)N1CCN(CCC2NC(=O)c3ccccc23)CC1 InChI=1S/C21H25N3O/c1-16-6-8-17(9-7-16)24-14-12-23(13-15-24)11-10-20-18-4-2-3-5-19(18)21(25)22-20/h2-9,20H,10-15H2,1H3,(H,22,25) FOEFMWUQXMNIHK-UHFFFAOYSA-N 50070520 3-[2-(4-p-Tolyl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one::CHEMBL287078 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9949601 103964381 CHEMBL287078 ZINC29242745 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121749 Cc1ccc(cc1C)N1CCN(CC[C@H]2NC(=O)c3ccccc23)CC1 InChI=1S/C22H27N3O/c1-16-7-8-18(15-17(16)2)25-13-11-24(12-14-25)10-9-21-19-5-3-4-6-20(19)22(26)23-21/h3-8,15,21H,9-14H2,1-2H3,(H,23,26)/t21-/m1/s1 WQEPZBNLBWDIRZ-OAQYLSRUSA-N 50070518 (R)-3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL35093::PD-172939 D(2) dopamine receptor Homo sapiens 2748.0 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9928335 103964379 CHEMBL35093 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121755 COc1ccc(cc1)N1CCN(CCC2N(C)C(=O)c3ccccc23)CC1 InChI=1S/C22H27N3O2/c1-23-21(19-5-3-4-6-20(19)22(23)26)11-12-24-13-15-25(16-14-24)17-7-9-18(27-2)10-8-17/h3-10,21H,11-16H2,1-2H3 JSGIEHICMIFPBV-UHFFFAOYSA-N 50070510 3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one::CHEMBL35114 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283889 103964371 CHEMBL35114 ZINC29243705 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121757 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OGJGQVFWEPNYSB-UHFFFAOYSA-N 85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853 D(2) dopamine receptor Homo sapiens 908 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L74 6IQL 5311200 136351193 CHEMBL555670CHEMBL267014 3303 ZINC25760037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121761 Cc1ccc(cc1C)C1CCN(CCC2NC(=O)c3ccccc23)CC1 InChI=1S/C23H28N2O/c1-16-7-8-19(15-17(16)2)18-9-12-25(13-10-18)14-11-22-20-5-3-4-6-21(20)23(26)24-22/h3-8,15,18,22H,9-14H2,1-2H3,(H,24,26) OBHCEADEAPCRBN-UHFFFAOYSA-N 50070521 3-{2-[4-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL37604 D(2) dopamine receptor Homo sapiens 1209 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283757 103964382 CHEMBL37604 ZINC29308220 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121762 Cc1ccc(cc1C)N1CCN(CC[C@@H]2NC(=O)c3ccccc23)CC1 InChI=1S/C22H27N3O/c1-16-7-8-18(15-17(16)2)25-13-11-24(12-14-25)10-9-21-19-5-3-4-6-20(19)22(26)23-21/h3-8,15,21H,9-14H2,1-2H3,(H,23,26)/t21-/m0/s1 WQEPZBNLBWDIRZ-NRFANRHFSA-N 50070514 (S)-3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one::3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one (PD-18126)::CHEMBL37170::PD-172938::PD-18126 D(2) dopamine receptor Homo sapiens 5882.0 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search RMZ 7AMJ 9798466 103964375 CHEMBL37170 ZINC03827164 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121766 CN1C(CCN2CCN(CC2)c2ccc(C)c(C)c2)c2ccccc2C1=O InChI=1S/C23H29N3O/c1-17-8-9-19(16-18(17)2)26-14-12-25(13-15-26)11-10-22-20-6-4-5-7-21(20)23(27)24(22)3/h4-9,16,22H,10-15H2,1-3H3 XFXYHGUUKCNNDR-UHFFFAOYSA-N 50070525 3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one::CHEMBL35182 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283891 103964386 CHEMBL35182 ZINC29243971 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50121768 Cc1nc(sc1C)N1CCN(CCC2NC(=O)c3ccccc23)CC1 InChI=1S/C19H24N4OS/c1-13-14(2)25-19(20-13)23-11-9-22(10-12-23)8-7-17-15-5-3-4-6-16(15)18(24)21-17/h3-6,17H,7-12H2,1-2H3,(H,21,24) RTOJYNJWSUUREU-UHFFFAOYSA-N 50070519 3-{2-[4-(4,5-Dimethyl-thiazol-2-yl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL38349 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(98)00252-2 10.7270/Q2WH2P54 9873377 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820085 103964380 CHEMBL38349 ZINC53150616 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124283 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C28H29Cl2N3O/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24/h1-2,5-11,19H,3-4,12-18H2,(H,31,34) YJPWVCIGSHWNON-UHFFFAOYSA-N 50071959 9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL300780::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide D(2) dopamine receptor Homo sapiens 217 ChEMBL 10.1016/s0960-894x(98)00469-7 10.7270/Q200018M 9873609 Yuan, J; Chen, X; Brodbeck, R; Primus, R; Braun, J; Wasley, JW; Thurkauf, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9891901 103965649 CHEMBL300780 6674 ZINC01545255 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124284 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc4-c5ccccc5-c4c3)CC2)c1Cl InChI=1S/C27H27Cl2N3O/c28-24-8-5-9-25(26(24)29)32-16-14-31(15-17-32)13-4-3-12-30-27(33)19-10-11-22-20-6-1-2-7-21(20)23(22)18-19/h1-2,5-11,18H,3-4,12-17H2,(H,30,33) JUXYQVLOCMVIJF-UHFFFAOYSA-N 50071958 Biphenylene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL419505 D(2) dopamine receptor Homo sapiens 262 ChEMBL 10.1016/s0960-894x(98)00469-7 10.7270/Q200018M 9873609 Yuan, J; Chen, X; Brodbeck, R; Primus, R; Braun, J; Wasley, JW; Thurkauf, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21460314 103965648 CHEMBL419505 ZINC01545876 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124101 C(N1CCN(CC1)c1cccc2[nH]cnc12)c1ccccc1 InChI=1S/C18H20N4/c1-2-5-15(6-3-1)13-21-9-11-22(12-10-21)17-8-4-7-16-18(17)20-14-19-16/h1-8,14H,9-13H2,(H,19,20) ZNBOBGDGUIWKPE-UHFFFAOYSA-N 50071852 4-(4-Benzyl-piperazin-1-yl)-1H-benzoimidazole::CHEMBL88837 D(2) dopamine receptor Homo sapiens 258 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323762 103965562 CHEMBL88837 ZINC26579141 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124102 Brc1ccc(N2CCN(Cc3ccccc3)CC2)c2cc[nH]c12 InChI=1S/C19H20BrN3/c20-17-6-7-18(16-8-9-21-19(16)17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-9,21H,10-14H2 RBUDKKJLRVBPDA-UHFFFAOYSA-N 50071853 4-(4-Benzyl-piperazin-1-yl)-7-bromo-1H-indole::CHEMBL90476 D(2) dopamine receptor Homo sapiens 47 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323962 103965563 CHEMBL90476 ZINC26650889 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124106 O=c1[nH]c2cccc(N3CCN(Cc4ccccc4)CC3)c2[nH]1 InChI=1S/C18H20N4O/c23-18-19-15-7-4-8-16(17(15)20-18)22-11-9-21(10-12-22)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H2,19,20,23) MKJHGVZTPBBKML-UHFFFAOYSA-N 50071854 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL315864 D(2) dopamine receptor Homo sapiens 87 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18414156 103965564 CHEMBL315864 ZINC26648578 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124111 O=C1Cc2c(N1)cccc2N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21N3O/c23-19-13-16-17(20-19)7-4-8-18(16)22-11-9-21(10-12-22)14-15-5-2-1-3-6-15/h1-8H,9-14H2,(H,20,23) TUVRDSTTWFDDHW-UHFFFAOYSA-N 50071856 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-indol-2-one::CHEMBL314952 D(2) dopamine receptor Homo sapiens 8 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995379 103965566 CHEMBL314952 ZINC26639952 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124113 Clc1ccc2[nH]ccc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3/c20-17-6-7-18-16(8-9-21-18)19(17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-9,21H,10-14H2 IRFLVVGRMBDQSJ-UHFFFAOYSA-N 50071858 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole::CHEMBL311539 D(2) dopamine receptor Homo sapiens 81 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323978 103965568 CHEMBL311539 ZINC26580242 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124114 FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H19F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H,23,24) PSWUORNVMIRUSW-UHFFFAOYSA-N 50071855 4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-benzoimidazole::CHEMBL88289 D(2) dopamine receptor Homo sapiens 4.1 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323763 103965565 CHEMBL88289 ZINC26579142 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124120 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Homo sapiens 246 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124128 Clc1ccc2NC(=O)Cc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3O/c20-16-6-7-17-15(12-18(24)21-17)19(16)23-10-8-22(9-11-23)13-14-4-2-1-3-5-14/h1-7H,8-13H2,(H,21,24) PIPVZEXRFVHTJJ-UHFFFAOYSA-N 50071859 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1,3-dihydro-indol-2-one::CHEMBL330108 D(2) dopamine receptor Homo sapiens 540 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323780 103965569 CHEMBL330108 ZINC26645609 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50124135 C(N1CCN(CC1)c1cccc2[nH]ccc12)c1ccccc1 InChI=1S/C19H21N3/c1-2-5-16(6-3-1)15-21-11-13-22(14-12-21)19-8-4-7-18-17(19)9-10-20-18/h1-10,20H,11-15H2 JLZIBIQTDGMAFZ-UHFFFAOYSA-N 50071857 4-(4-Benzyl-piperazin-1-yl)-1H-indole::CHEMBL328051 D(2) dopamine receptor Homo sapiens 53 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2728532 103965567 CHEMBL328051 ZINC53006914 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128422 NC(=O)[C@H]1CS[C@@H]2CC[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-9-24-12-4-6-16(15(23)20(11)12)5-2-8-19(16)14(22)10-3-1-7-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11+,12+,16+/m0/s1 KMWWIPJCECUZFY-XSUJLISDSA-N 50074093 (2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl)hexahydrospiro[pyrrolidine-2,6'-thiazolo[3,2-a]pyridine]-3'-carboxamide::CHEMBL156651::RHPS4 D(2) dopamine receptor Homo sapiens 260 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020914 103967363 CHEMBL156651 ZINC13556562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128423 NC(=O)C1CCS[C@@H]2C[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-4-8-24-12-9-16(15(23)20(11)12)5-2-7-19(16)14(22)10-3-1-6-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11?,12+,16+/m0/s1 WAMSRMUXQPANBA-UTEDSILMSA-N 50074092 6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(2'R,8a'R)-spiro[4H,5H-pyrrole-2,7'-perhydropyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide::CHEMBL156164 D(2) dopamine receptor Homo sapiens 168 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372199 103967362 CHEMBL156164 ZINC27710897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128424 NC(=O)[C@H]1CS[C@@H]2CC[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-9-24-12-4-6-16(15(23)20(11)12)5-2-8-19(16)14(22)10-3-1-7-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11+,12+,16+/m0/s1 KMWWIPJCECUZFY-XSUJLISDSA-N 50074093 (2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl)hexahydrospiro[pyrrolidine-2,6'-thiazolo[3,2-a]pyridine]-3'-carboxamide::CHEMBL156651::RHPS4 D(2) dopamine receptor Homo sapiens 0.09 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020914 103967363 CHEMBL156651 ZINC13556562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128425 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N 50060601 (E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H,3H)-dione::(S)-Pyrrolidine-2-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide::6-((E)-3-Oxo-3-phenyl-propenyl)-1H-pyrimidine-2,4-dione::CHEMBL317488::L-pro-L-leu-gly-NH2::L-prolyl-L-leucylglycinamide::Pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide D(2) dopamine receptor Homo sapiens 60 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92910 103956281 CHEMBL317488 ZINC04899446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128426 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N 50060601 (E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H,3H)-dione::(S)-Pyrrolidine-2-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide::6-((E)-3-Oxo-3-phenyl-propenyl)-1H-pyrimidine-2,4-dione::CHEMBL317488::L-pro-L-leu-gly-NH2::L-prolyl-L-leucylglycinamide::Pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide D(2) dopamine receptor Homo sapiens 60.0 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92910 103956281 CHEMBL317488 ZINC04899446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128427 NC(=O)[C@H]1CS[C@@H]2CC[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-9-24-12-4-6-16(15(23)20(11)12)5-2-8-19(16)14(22)10-3-1-7-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11+,12+,16+/m0/s1 KMWWIPJCECUZFY-XSUJLISDSA-N 50074093 (2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl)hexahydrospiro[pyrrolidine-2,6'-thiazolo[3,2-a]pyridine]-3'-carboxamide::CHEMBL156651::RHPS4 D(2) dopamine receptor Homo sapiens 260 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020914 103967363 CHEMBL156651 ZINC13556562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128428 NC(=O)C1CCS[C@@H]2C[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-4-8-24-12-9-16(15(23)20(11)12)5-2-7-19(16)14(22)10-3-1-6-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11?,12+,16+/m0/s1 WAMSRMUXQPANBA-UTEDSILMSA-N 50074092 6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(2'R,8a'R)-spiro[4H,5H-pyrrole-2,7'-perhydropyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide::CHEMBL156164 D(2) dopamine receptor Homo sapiens 0.031 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372199 103967362 CHEMBL156164 ZINC27710897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128429 NC(=O)C1CCS[C@@H]2C[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-4-8-24-12-9-16(15(23)20(11)12)5-2-7-19(16)14(22)10-3-1-6-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11?,12+,16+/m0/s1 WAMSRMUXQPANBA-UTEDSILMSA-N 50074092 6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(2'R,8a'R)-spiro[4H,5H-pyrrole-2,7'-perhydropyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide::CHEMBL156164 D(2) dopamine receptor Homo sapiens 0.122 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372199 103967362 CHEMBL156164 ZINC27710897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128430 NC(=O)[C@H]1CS[C@@H]2CC[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-9-24-12-4-6-16(15(23)20(11)12)5-2-8-19(16)14(22)10-3-1-7-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11+,12+,16+/m0/s1 KMWWIPJCECUZFY-XSUJLISDSA-N 50074093 (2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl)hexahydrospiro[pyrrolidine-2,6'-thiazolo[3,2-a]pyridine]-3'-carboxamide::CHEMBL156651::RHPS4 D(2) dopamine receptor Homo sapiens 0.05 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020914 103967363 CHEMBL156651 ZINC13556562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128431 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N 50060601 (E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H,3H)-dione::(S)-Pyrrolidine-2-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide::6-((E)-3-Oxo-3-phenyl-propenyl)-1H-pyrimidine-2,4-dione::CHEMBL317488::L-pro-L-leu-gly-NH2::L-prolyl-L-leucylglycinamide::Pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide D(2) dopamine receptor Homo sapiens 0.13 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92910 103956281 CHEMBL317488 ZINC04899446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128432 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N 50060601 (E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H,3H)-dione::(S)-Pyrrolidine-2-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide::6-((E)-3-Oxo-3-phenyl-propenyl)-1H-pyrimidine-2,4-dione::CHEMBL317488::L-pro-L-leu-gly-NH2::L-prolyl-L-leucylglycinamide::Pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide D(2) dopamine receptor Homo sapiens 0.06 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92910 103956281 CHEMBL317488 ZINC04899446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128433 NC(=O)C1CCS[C@@H]2C[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-4-8-24-12-9-16(15(23)20(11)12)5-2-7-19(16)14(22)10-3-1-6-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11?,12+,16+/m0/s1 WAMSRMUXQPANBA-UTEDSILMSA-N 50074092 6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(2'R,8a'R)-spiro[4H,5H-pyrrole-2,7'-perhydropyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide::CHEMBL156164 D(2) dopamine receptor Homo sapiens 246 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372199 103967362 CHEMBL156164 ZINC27710897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128434 NC(=O)C1CCS[C@@H]2C[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-4-8-24-12-9-16(15(23)20(11)12)5-2-7-19(16)14(22)10-3-1-6-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11?,12+,16+/m0/s1 WAMSRMUXQPANBA-UTEDSILMSA-N 50074092 6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(2'R,8a'R)-spiro[4H,5H-pyrrole-2,7'-perhydropyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide::CHEMBL156164 D(2) dopamine receptor Homo sapiens 246 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372199 103967362 CHEMBL156164 ZINC27710897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128435 NC(=O)C1CCS[C@@H]2C[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-4-8-24-12-9-16(15(23)20(11)12)5-2-7-19(16)14(22)10-3-1-6-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11?,12+,16+/m0/s1 WAMSRMUXQPANBA-UTEDSILMSA-N 50074092 6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(2'R,8a'R)-spiro[4H,5H-pyrrole-2,7'-perhydropyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide::CHEMBL156164 D(2) dopamine receptor Homo sapiens 0.064 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372199 103967362 CHEMBL156164 ZINC27710897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128436 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N 50060601 (E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H,3H)-dione::(S)-Pyrrolidine-2-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide::6-((E)-3-Oxo-3-phenyl-propenyl)-1H-pyrimidine-2,4-dione::CHEMBL317488::L-pro-L-leu-gly-NH2::L-prolyl-L-leucylglycinamide::Pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide D(2) dopamine receptor Homo sapiens 60.1 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92910 103956281 CHEMBL317488 ZINC04899446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128437 NC(=O)[C@H]1CS[C@@H]2CC[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-9-24-12-4-6-16(15(23)20(11)12)5-2-8-19(16)14(22)10-3-1-7-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11+,12+,16+/m0/s1 KMWWIPJCECUZFY-XSUJLISDSA-N 50074093 (2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl)hexahydrospiro[pyrrolidine-2,6'-thiazolo[3,2-a]pyridine]-3'-carboxamide::CHEMBL156651::RHPS4 D(2) dopamine receptor Homo sapiens 0.196 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020914 103967363 CHEMBL156651 ZINC13556562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128438 NC(=O)[C@H]1CS[C@@H]2CC[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-9-24-12-4-6-16(15(23)20(11)12)5-2-8-19(16)14(22)10-3-1-7-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11+,12+,16+/m0/s1 KMWWIPJCECUZFY-XSUJLISDSA-N 50074093 (2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl)hexahydrospiro[pyrrolidine-2,6'-thiazolo[3,2-a]pyridine]-3'-carboxamide::CHEMBL156651::RHPS4 D(2) dopamine receptor Homo sapiens 0.067 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020914 103967363 CHEMBL156651 ZINC13556562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128439 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N 50060601 (E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H,3H)-dione::(S)-Pyrrolidine-2-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide::6-((E)-3-Oxo-3-phenyl-propenyl)-1H-pyrimidine-2,4-dione::CHEMBL317488::L-pro-L-leu-gly-NH2::L-prolyl-L-leucylglycinamide::Pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide D(2) dopamine receptor Homo sapiens 73.2 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92910 103956281 CHEMBL317488 ZINC04899446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128440 NC(=O)C1CCS[C@@H]2C[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-4-8-24-12-9-16(15(23)20(11)12)5-2-7-19(16)14(22)10-3-1-6-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11?,12+,16+/m0/s1 WAMSRMUXQPANBA-UTEDSILMSA-N 50074092 6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(2'R,8a'R)-spiro[4H,5H-pyrrole-2,7'-perhydropyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide::CHEMBL156164 D(2) dopamine receptor Homo sapiens 0.071 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372199 103967362 CHEMBL156164 ZINC27710897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128441 NC(=O)[C@H]1CS[C@@H]2CC[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-9-24-12-4-6-16(15(23)20(11)12)5-2-8-19(16)14(22)10-3-1-7-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11+,12+,16+/m0/s1 KMWWIPJCECUZFY-XSUJLISDSA-N 50074093 (2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl)hexahydrospiro[pyrrolidine-2,6'-thiazolo[3,2-a]pyridine]-3'-carboxamide::CHEMBL156651::RHPS4 D(2) dopamine receptor Homo sapiens 190 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020914 103967363 CHEMBL156651 ZINC13556562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128442 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N 50060601 (E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H,3H)-dione::(S)-Pyrrolidine-2-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide::6-((E)-3-Oxo-3-phenyl-propenyl)-1H-pyrimidine-2,4-dione::CHEMBL317488::L-pro-L-leu-gly-NH2::L-prolyl-L-leucylglycinamide::Pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide D(2) dopamine receptor Homo sapiens 0.09 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92910 103956281 CHEMBL317488 ZINC04899446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128443 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1 NOOJLZTTWSNHOX-UWVGGRQHSA-N 50060601 (E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H,3H)-dione::(S)-Pyrrolidine-2-carboxylic acid [(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide::6-((E)-3-Oxo-3-phenyl-propenyl)-1H-pyrimidine-2,4-dione::CHEMBL317488::L-pro-L-leu-gly-NH2::L-prolyl-L-leucylglycinamide::Pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-3-methyl-butyl]-amide D(2) dopamine receptor Homo sapiens 0.04 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92910 103956281 CHEMBL317488 ZINC04899446 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128444 NC(=O)[C@H]1CS[C@@H]2CC[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-9-24-12-4-6-16(15(23)20(11)12)5-2-8-19(16)14(22)10-3-1-7-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11+,12+,16+/m0/s1 KMWWIPJCECUZFY-XSUJLISDSA-N 50074093 (2R,3'S,8a'R)-5'-oxo-1-((S)-pyrrolidine-2-carbonyl)hexahydrospiro[pyrrolidine-2,6'-thiazolo[3,2-a]pyridine]-3'-carboxamide::CHEMBL156651::RHPS4 D(2) dopamine receptor Homo sapiens 188 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020914 103967363 CHEMBL156651 ZINC13556562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50128445 NC(=O)C1CCS[C@@H]2C[C@]3(CCCN3C(=O)[C@@H]3CCCN3)C(=O)N12 InChI=1S/C16H24N4O3S/c17-13(21)11-4-8-24-12-9-16(15(23)20(11)12)5-2-7-19(16)14(22)10-3-1-6-18-10/h10-12,18H,1-9H2,(H2,17,21)/t10-,11?,12+,16+/m0/s1 WAMSRMUXQPANBA-UTEDSILMSA-N 50074092 6'-oxo-1-[(2S)-tetrahydro-1H-2-pyrrolylcarbonyl]-(2'R,8a'R)-spiro[4H,5H-pyrrole-2,7'-perhydropyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide::CHEMBL156164 D(2) dopamine receptor Homo sapiens 196 ChEMBL 10.1021/jm980525q 10.7270/Q27080MW 10052970 Khalil, EM; Ojala, WH; Pradhan, A; Nair, VD; Gleason, WB; Mishra, RK; Johnson, RL University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372199 103967362 CHEMBL156164 ZINC27710897 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50127391 COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1 WZOMJNATDSYQHS-ZPWQMVEJSA-N 50131359 (3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114 D(2) dopamine receptor Homo sapiens 959 ChEMBL 10.1021/jm049619s 10.7270/Q22F7MZC 15771448 Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324765 104022543 CHEMBL328114 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50127550 COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1 YMYZKGIHGMHZDL-WDAWEKNVSA-N 50131347 (3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm049619s 10.7270/Q22F7MZC 15771448 Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324972 104022531 CHEMBL419316 ZINC22930623 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50127642 COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1 JWYUBODPEUBFLH-FSTMKDAKSA-N 50131346 (3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157 D(2) dopamine receptor Homo sapiens 230 ChEMBL 10.1021/jm049619s 10.7270/Q22F7MZC 15771448 Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324800 104022530 CHEMBL91157 ZINC22930620 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50127696 COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1 XHLHZPFSBCZVEA-HOFKKMOUSA-N 50131351 (3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm049619s 10.7270/Q22F7MZC 15771448 Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324737 104022535 CHEMBL92860 ZINC22445308 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50126807 O=c1ccc2ccc(OCCCN3CCN(CC3)c3ccccc3)cc2o1 InChI=1S/C22H24N2O3/c25-22-10-8-18-7-9-20(17-21(18)27-22)26-16-4-11-23-12-14-24(15-13-23)19-5-2-1-3-6-19/h1-3,5-10,17H,4,11-16H2 MULLDMIPFVHJIA-UHFFFAOYSA-N 50073271 7-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-chromen-2-one::CHEMBL120590 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1016/s0960-894x(98)00646-5 10.7270/Q2CV4GWM 9934472 Teran, C; Santana, L; Uriarte, E; Fall, Y; Unelius, L; Tolf, BR University of Vigo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9976024 103966698 CHEMBL120590 ZINC27109768 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50126812 Cc1cc2ccc(OCCCN3CCN(CC3)c3ccccc3)cc2oc1=O InChI=1S/C23H26N2O3/c1-18-16-19-8-9-21(17-22(19)28-23(18)26)27-15-5-10-24-11-13-25(14-12-24)20-6-3-2-4-7-20/h2-4,6-9,16-17H,5,10-15H2,1H3 GKYBNMJPQSRWPC-UHFFFAOYSA-N 50073274 3-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-chromen-2-one::CHEMBL422788 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1016/s0960-894x(98)00646-5 10.7270/Q2CV4GWM 9934472 Teran, C; Santana, L; Uriarte, E; Fall, Y; Unelius, L; Tolf, BR University of Vigo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073274&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10384998 103966701 CHEMBL422788 ZINC27181338 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50126814 Cc1c(C)c(=O)oc2cc(OCCCN3CCN(CC3)c3ccccc3)ccc12 InChI=1S/C24H28N2O3/c1-18-19(2)24(27)29-23-17-21(9-10-22(18)23)28-16-6-11-25-12-14-26(15-13-25)20-7-4-3-5-8-20/h3-5,7-10,17H,6,11-16H2,1-2H3 LNAQGJPALKPMLJ-UHFFFAOYSA-N 50073273 3,4-Dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-chromen-2-one::CHEMBL120661 D(2) dopamine receptor Homo sapiens 5.9 ChEMBL 10.1016/s0960-894x(98)00646-5 10.7270/Q2CV4GWM 9934472 Teran, C; Santana, L; Uriarte, E; Fall, Y; Unelius, L; Tolf, BR University of Vigo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10340492 103966700 CHEMBL120661 ZINC27109770 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50126815 Cc1cc(=O)oc2cc(OCCCN3CCN(CC3)c3ccccc3)ccc12 InChI=1S/C23H26N2O3/c1-18-16-23(26)28-22-17-20(8-9-21(18)22)27-15-5-10-24-11-13-25(14-12-24)19-6-3-2-4-7-19/h2-4,6-9,16-17H,5,10-15H2,1H3 ZYBLSQVXWVJACW-UHFFFAOYSA-N 50073272 4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-chromen-2-one::CHEMBL52096 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1016/s0960-894x(98)00646-5 10.7270/Q2CV4GWM 9934472 Teran, C; Santana, L; Uriarte, E; Fall, Y; Unelius, L; Tolf, BR University of Vigo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10317514 103966699 CHEMBL52096 ZINC13486988 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130890 COc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C19H22N4O/c1-24-17-6-4-16(5-7-17)23-11-9-22(10-12-23)14-15-13-21-19-18(15)3-2-8-20-19/h2-8,13H,9-12,14H2,1H3,(H,20,21) NNGCXJPRHBHODU-UHFFFAOYSA-N 50075360 3-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL28607 D(2) dopamine receptor Homo sapiens >1500 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9905249 103968499 CHEMBL28607 ZINC28771301 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130894 Clc1ccc(cc1)N1CCN(CCc2cc3cccnc3[nH]2)CC1 InChI=1S/C19H21ClN4/c20-16-3-5-18(6-4-16)24-12-10-23(11-13-24)9-7-17-14-15-2-1-8-21-19(15)22-17/h1-6,8,14H,7,9-13H2,(H,21,22) QUCXOFSWCJSLHA-UHFFFAOYSA-N 50075359 2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-1H-pyrrolo[2,3-b]pyridine::CHEMBL347155 D(2) dopamine receptor Homo sapiens 800 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075359&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370047 103968498 CHEMBL347155 ZINC27655986 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130896 C(Cc1ccccc1)C1CCN(Cc2cc3cccnc3[nH]2)CC1 InChI=1S/C21H25N3/c1-2-5-17(6-3-1)8-9-18-10-13-24(14-11-18)16-20-15-19-7-4-12-22-21(19)23-20/h1-7,12,15,18H,8-11,13-14,16H2,(H,22,23) DZHAENXWCJQFRP-UHFFFAOYSA-N 50075357 2-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL156732 D(2) dopamine receptor Homo sapiens 200 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075357&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10245409 103968496 CHEMBL156732 ZINC27652945 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130897 C(Cc1ccccc1)C1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C21H25N3/c1-2-5-17(6-3-1)8-9-18-10-13-24(14-11-18)16-19-15-23-21-20(19)7-4-12-22-21/h1-7,12,15,18H,8-11,13-14,16H2,(H,22,23) YLBNUQZHSMXDAJ-UHFFFAOYSA-N 50075362 3-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL155207 D(2) dopamine receptor Homo sapiens 1100 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075362&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21462964 103968501 CHEMBL155207 ZINC00022901 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130908 C(N1CCc2ccccc2C1)c1cc2cccnc2[nH]1 InChI=1S/C17H17N3/c1-2-5-15-11-20(9-7-13(15)4-1)12-16-10-14-6-3-8-18-17(14)19-16/h1-6,8,10H,7,9,11-12H2,(H,18,19) ZNJRNDKOAPREMV-UHFFFAOYSA-N 50075364 2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline::CHEMBL156896 D(2) dopamine receptor Homo sapiens 600 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370009 103968503 CHEMBL156896 ZINC27648101 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130909 C(Cc1cc2cccnc2[nH]1)N1CCC(\C=C\c2ccccc2)=CC1 InChI=1S/C22H23N3/c1-2-5-18(6-3-1)8-9-19-10-14-25(15-11-19)16-12-21-17-20-7-4-13-23-22(20)24-21/h1-10,13,17H,11-12,14-16H2,(H,23,24)/b9-8+ ZCOIFCGQTTYDFL-CMDGGOBGSA-N 50075365 2-[2-(4-Styryl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL154482 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075365&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370032 103968504 CHEMBL154482 ZINC27650201 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130911 C(N1CCc2ccccc2C1)c1c[nH]c2ncccc12 InChI=1S/C17H17N3/c1-2-5-14-11-20(9-7-13(14)4-1)12-15-10-19-17-16(15)6-3-8-18-17/h1-6,8,10H,7,9,11-12H2,(H,18,19) BGJDVOKZOHLJPT-UHFFFAOYSA-N 50075363 2-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline::CHEMBL154286 D(2) dopamine receptor Homo sapiens 640 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075363&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21462980 103968502 CHEMBL154286 ZINC27648481 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130913 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OGJGQVFWEPNYSB-UHFFFAOYSA-N 85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853 D(2) dopamine receptor Homo sapiens 960 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L74 6IQL 5311200 136351193 CHEMBL555670CHEMBL267014 3303 ZINC25760037 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50130914 COc1ccc(cc1)N1CCN(CCc2c[nH]c3ncccc23)CC1 InChI=1S/C20H24N4O/c1-25-18-6-4-17(5-7-18)24-13-11-23(12-14-24)10-8-16-15-22-20-19(16)3-2-9-21-20/h2-7,9,15H,8,10-14H2,1H3,(H,21,22) DUTVAWSMMMBCQT-UHFFFAOYSA-N 50075356 3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1H-pyrrolo[2,3-b]pyridine::CHEMBL347291 D(2) dopamine receptor Homo sapiens 900 ChEMBL 10.1016/s0960-894x(99)00025-6 10.7270/Q2NV9HD4 10098669 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370058 103968495 CHEMBL347291 ZINC27654752 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134306 Cc1c(cnn1C1CCN(Cc2ccccc2)CC1)-c1ccccc1 InChI=1S/C22H25N3/c1-18-22(20-10-6-3-7-11-20)16-23-25(18)21-12-14-24(15-13-21)17-19-8-4-2-5-9-19/h2-11,16,21H,12-15,17H2,1H3 IBMJCDACSWDYQN-UHFFFAOYSA-N 50076996 1-Benzyl-4-(5-methyl-4-phenyl-pyrazol-1-yl)-piperidine::CHEMBL25772 D(2) dopamine receptor Homo sapiens 140 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9949442 103969839 CHEMBL25772 ZINC00006683 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134313 Cc1c(cnn1C1CCN(Cc2cccc(c2)C#N)CC1)-c1ccccc1 InChI=1S/C23H24N4/c1-18-23(21-8-3-2-4-9-21)16-25-27(18)22-10-12-26(13-11-22)17-20-7-5-6-19(14-20)15-24/h2-9,14,16,22H,10-13,17H2,1H3 FBJIUWHTOIOHGN-UHFFFAOYSA-N 50077002 3-[4-(5-Methyl-4-phenyl-pyrazol-1-yl)-piperidin-1-ylmethyl]-benzonitrile::CHEMBL24052 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077002&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10360923 103969845 CHEMBL24052 ZINC00838761 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134315 Cc1cc(-c2ccccc2)n(n1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C22H25N3/c1-18-16-22(20-10-6-3-7-11-20)25(23-18)21-12-14-24(15-13-21)17-19-8-4-2-5-9-19/h2-11,16,21H,12-15,17H2,1H3 AHVVCJSEQJZGNV-UHFFFAOYSA-N 50077000 1-Benzyl-4-(3-methyl-5-phenyl-pyrazol-1-yl)-piperidine::CHEMBL24809 D(2) dopamine receptor Homo sapiens 310 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077000&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44459452 103969843 CHEMBL24809 ZINC28755193 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134316 Cc1nn(cc1-c1ccccc1)C1CCN(Cc2cccc(Cl)c2)CC1 InChI=1S/C22H24ClN3/c1-17-22(19-7-3-2-4-8-19)16-26(24-17)21-10-12-25(13-11-21)15-18-6-5-9-20(23)14-18/h2-9,14,16,21H,10-13,15H2,1H3 UGAZJRFHXXPSOK-UHFFFAOYSA-N 50077004 1-(3-Chloro-benzyl)-4-(3-methyl-4-phenyl-pyrazol-1-yl)-piperidine::CHEMBL287412 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077004&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12052258 103969847 CHEMBL287412 ZINC00838767 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134324 Cc1c(nnn1C1CCN(Cc2ccccc2)CC1)-c1ccccc1 InChI=1S/C21H24N4/c1-17-21(19-10-6-3-7-11-19)22-23-25(17)20-12-14-24(15-13-20)16-18-8-4-2-5-9-18/h2-11,20H,12-16H2,1H3 VUXXDICFUUFOIZ-UHFFFAOYSA-N 50077008 1-Benzyl-4-(5-methyl-4-phenyl-[1,2,3]triazol-1-yl)-piperidine::CHEMBL284346 D(2) dopamine receptor Homo sapiens 1600 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077008&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219167 103969851 CHEMBL284346 ZINC00021391 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134327 C(N1CCC(CC1)n1nnc(n1)-c1ccccc1)c1ccccc1 InChI=1S/C19H21N5/c1-3-7-16(8-4-1)15-23-13-11-18(12-14-23)24-21-19(20-22-24)17-9-5-2-6-10-17/h1-10,18H,11-15H2 DWESQFNWEXIRSK-UHFFFAOYSA-N 50076999 1-Benzyl-4-(5-phenyl-tetrazol-2-yl)-piperidine::CHEMBL24539 D(2) dopamine receptor Homo sapiens 1100 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219144 103969842 CHEMBL24539 ZINC00021392 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134332 Cc1c([nH]nc1-c1ccccc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C22H25N3/c1-17-21(19-10-6-3-7-11-19)23-24-22(17)20-12-14-25(15-13-20)16-18-8-4-2-5-9-18/h2-11,20H,12-16H2,1H3,(H,23,24) PJMOAMQVWVRXEQ-UHFFFAOYSA-N 50077006 1-Benzyl-4-(4-methyl-5-phenyl-1H-pyrazol-3-yl)-piperidine::CHEMBL281195 D(2) dopamine receptor Homo sapiens 90 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077006&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44459463 103969849 CHEMBL281195 ZINC28265074 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134334 Cc1c(cnn1C1CCN(Cc2cccc(Cl)c2)CC1)-c1ccccc1 InChI=1S/C22H24ClN3/c1-17-22(19-7-3-2-4-8-19)15-24-26(17)21-10-12-25(13-11-21)16-18-6-5-9-20(23)14-18/h2-9,14-15,21H,10-13,16H2,1H3 VIGLYHYRWJDUPG-UHFFFAOYSA-N 50077010 1-(3-Chloro-benzyl)-4-(5-methyl-4-phenyl-pyrazol-1-yl)-piperidine::CHEMBL24051 D(2) dopamine receptor Homo sapiens 370 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077010&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219164 103969853 CHEMBL24051 ZINC00838763 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134335 Cc1nn(cc1-c1ccccc1)C1CCN(Cc2cccc(c2)C#N)CC1 InChI=1S/C23H24N4/c1-18-23(21-8-3-2-4-9-21)17-27(25-18)22-10-12-26(13-11-22)16-20-7-5-6-19(14-20)15-24/h2-9,14,17,22H,10-13,16H2,1H3 RXSODUHUZZRAAV-UHFFFAOYSA-N 50077003 3-[4-(3-Methyl-4-phenyl-pyrazol-1-yl)-piperidin-1-ylmethyl]-benzonitrile::CHEMBL26120 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077003&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219176 103969846 CHEMBL26120 ZINC00838765 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134336 C(N1CCC(CC1)c1cc(n[nH]1)-c1ccccc1)c1ccccc1 InChI=1S/C21H23N3/c1-3-7-17(8-4-1)16-24-13-11-19(12-14-24)21-15-20(22-23-21)18-9-5-2-6-10-18/h1-10,15,19H,11-14,16H2,(H,22,23) CEFKCGBMUZVVLI-UHFFFAOYSA-N 50059227 1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine::CHEMBL25938 D(2) dopamine receptor Homo sapiens 66 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059227&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10615437 103955071 CHEMBL25938 ZINC13763829 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134338 Cc1nn(cc1-c1ccccc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C22H25N3/c1-18-22(20-10-6-3-7-11-20)17-25(23-18)21-12-14-24(15-13-21)16-19-8-4-2-5-9-19/h2-11,17,21H,12-16H2,1H3 RFIMVYUKZRXUJB-UHFFFAOYSA-N 50077001 1-Benzyl-4-(3-methyl-4-phenyl-pyrazol-1-yl)-piperidine::CHEMBL279247 D(2) dopamine receptor Homo sapiens 6.1 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077001&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219157 103969844 CHEMBL279247 ZINC00021390 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134343 C(N1CCC(CC1)n1nccc1-c1ccccc1)c1ccccc1 InChI=1S/C21H23N3/c1-3-7-18(8-4-1)17-23-15-12-20(13-16-23)24-21(11-14-22-24)19-9-5-2-6-10-19/h1-11,14,20H,12-13,15-17H2 PRJNFNOLHGROQO-UHFFFAOYSA-N 50076997 1-Benzyl-4-(5-phenyl-pyrazol-1-yl)-piperidine::CHEMBL23537 D(2) dopamine receptor Homo sapiens 510 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076997&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219154 103969840 CHEMBL23537 ZINC00021395 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134346 C(N1CCC(CC1)n1cnc(c1)-c1ccccc1)c1ccccc1 InChI=1S/C21H23N3/c1-3-7-18(8-4-1)15-23-13-11-20(12-14-23)24-16-21(22-17-24)19-9-5-2-6-10-19/h1-10,16-17,20H,11-15H2 JCQGRHIIKSHVDZ-UHFFFAOYSA-N 50077005 1-Benzyl-4-(4-phenyl-imidazol-1-yl)-piperidine::CHEMBL287217 D(2) dopamine receptor Homo sapiens 450 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219166 103969848 CHEMBL287217 ZINC00021394 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134348 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 74 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134351 Cc1nnn(C2CCN(Cc3ccccc3)CC2)c1-c1ccccc1 InChI=1S/C21H24N4/c1-17-21(19-10-6-3-7-11-19)25(23-22-17)20-12-14-24(15-13-20)16-18-8-4-2-5-9-18/h2-11,20H,12-16H2,1H3 XWXQDIUFNJEKBY-UHFFFAOYSA-N 50076998 1-Benzyl-4-(4-methyl-5-phenyl-[1,2,3]triazol-1-yl)-piperidine::CHEMBL25887 D(2) dopamine receptor Homo sapiens 1200 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076998&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219156 103969841 CHEMBL25887 ZINC28755355 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134352 C(N1CCC(CC1)n1nnnc1-c1ccccc1)c1ccccc1 InChI=1S/C19H21N5/c1-3-7-16(8-4-1)15-23-13-11-18(12-14-23)24-19(20-21-22-24)17-9-5-2-6-10-17/h1-10,18H,11-15H2 WRQPPYQGOCMHJN-UHFFFAOYSA-N 50077009 1-Benzyl-4-(5-phenyl-tetrazol-1-yl)-piperidine::CHEMBL24603 D(2) dopamine receptor Homo sapiens >1800 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077009&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219173 103969852 CHEMBL24603 ZINC28755378 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50134353 C(N1CCC(CC1)n1cc(nn1)-c1ccccc1)c1ccccc1 InChI=1S/C20H22N4/c1-3-7-17(8-4-1)15-23-13-11-19(12-14-23)24-16-20(21-22-24)18-9-5-2-6-10-18/h1-10,16,19H,11-15H2 BVDQINYYEZPHTR-UHFFFAOYSA-N 50077007 1-Benzyl-4-(4-phenyl-[1,2,3]triazol-1-yl)-piperidine::CHEMBL24170 D(2) dopamine receptor Homo sapiens 460 ChEMBL 10.1016/s0960-894x(99)00169-9 10.7270/Q2C53K1C 10340615 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077007&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21219160 103969850 CHEMBL24170 ZINC00021393 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136220 OC1(CCN(CCCC(=O)c2ccc(F)cc2)C1)c1ccc(Cl)cc1 InChI=1S/C20H21ClFNO2/c21-17-7-5-16(6-8-17)20(25)11-13-23(14-20)12-1-2-19(24)15-3-9-18(22)10-4-15/h3-10,25H,1-2,11-14H2 BETHXCLHMRGYBW-UHFFFAOYSA-N 50185474 (+)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::(-)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(-)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-pyrrolidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::CHEMBL150161 D(2) dopamine receptor Homo sapiens 51 ChEMBL 10.1016/j.bmcl.2006.03.057 10.7270/Q2571BM5 16621538 Ablordeppey, SY; Lyles-Eggleston, M; Bricker, B; Zhang, W; Zhu, X; Goodman, C; Roth, BL Florida A&M University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906978 104069685 CHEMBL150161 ZINC12356157 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136406 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Homo sapiens 54 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138460 COc1cccc(CN2CCC(CC2)n2c(C)c([nH]c2=O)-c2ccccc2)c1 InChI=1S/C23H27N3O2/c1-17-22(19-8-4-3-5-9-19)24-23(27)26(17)20-11-13-25(14-12-20)16-18-7-6-10-21(15-18)28-2/h3-10,15,20H,11-14,16H2,1-2H3,(H,24,27) SVAAEZGFWVDPDN-UHFFFAOYSA-N 50079153 1-[1-(3-Methoxy-benzyl)-piperidin-4-yl]-5-methyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL91155 D(2) dopamine receptor Homo sapiens 900 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079153&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10547607 103971473 CHEMBL91155 ZINC13799248 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138465 Cn1c(cn(C2CCN(Cc3ccccc3)CC2)c1=O)-c1ccccc1 InChI=1S/C22H25N3O/c1-23-21(19-10-6-3-7-11-19)17-25(22(23)26)20-12-14-24(15-13-20)16-18-8-4-2-5-9-18/h2-11,17,20H,12-16H2,1H3 MXJQVJALKSFQKU-UHFFFAOYSA-N 50079158 1-(1-Benzyl-piperidin-4-yl)-3-methyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL91669 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783874 103971478 CHEMBL91669 ZINC00019662 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138468 Cc1c([nH]c(=O)n1C1CCN(Cc2cccc(C)c2)CC1)-c1ccccc1 InChI=1S/C23H27N3O/c1-17-7-6-8-19(15-17)16-25-13-11-21(12-14-25)26-18(2)22(24-23(26)27)20-9-4-3-5-10-20/h3-10,15,21H,11-14,16H2,1-2H3,(H,24,27) RUCVLTFMJJZXOA-UHFFFAOYSA-N 50079161 5-Methyl-1-[1-(3-methyl-benzyl)-piperidin-4-yl]-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL92859 D(2) dopamine receptor Homo sapiens 95 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079161&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10546540 103971481 CHEMBL92859 ZINC13799244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138471 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1ccc(C)cc1 InChI=1S/C23H27N3O/c1-17-8-10-20(11-9-17)22-18(2)26(23(27)24-22)21-12-14-25(15-13-21)16-19-6-4-3-5-7-19/h3-11,21H,12-16H2,1-2H3,(H,24,27) VYIBPAZWROJPIT-UHFFFAOYSA-N 50079162 1-(1-Benzyl-piperidin-4-yl)-5-methyl-4-p-tolyl-1,3-dihydro-imidazol-2-one::CHEMBL263162 D(2) dopamine receptor Homo sapiens 52 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079162&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666315 103971482 CHEMBL263162 ZINC13799213 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138474 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 74 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138478 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1ccc(F)cc1 InChI=1S/C22H24FN3O/c1-16-21(18-7-9-19(23)10-8-18)24-22(27)26(16)20-11-13-25(14-12-20)15-17-5-3-2-4-6-17/h2-10,20H,11-15H2,1H3,(H,24,27) OLUIVMRSUSSFJF-UHFFFAOYSA-N 50079155 1-(1-Benzyl-piperidin-4-yl)-4-(4-fluoro-phenyl)-5-methyl-1,3-dihydro-imidazol-2-one::CHEMBL92189 D(2) dopamine receptor Homo sapiens 290 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079155&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10690200 103971475 CHEMBL92189 ZINC13799209 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138480 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1ccc(Cl)cc1 InChI=1S/C22H24ClN3O/c1-16-21(18-7-9-19(23)10-8-18)24-22(27)26(16)20-11-13-25(14-12-20)15-17-5-3-2-4-6-17/h2-10,20H,11-15H2,1H3,(H,24,27) ZCDDPEAAEDRNJF-UHFFFAOYSA-N 50079159 1-(1-Benzyl-piperidin-4-yl)-4-(4-chloro-phenyl)-5-methyl-1,3-dihydro-imidazol-2-one::CHEMBL94023 D(2) dopamine receptor Homo sapiens 170 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643588 103971479 CHEMBL94023 ZINC00592271 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138483 O=C(NC1CCN(Cc2ccccc2)CC1)NC(=O)c1ccccc1 InChI=1S/C20H23N3O2/c24-19(17-9-5-2-6-10-17)22-20(25)21-18-11-13-23(14-12-18)15-16-7-3-1-4-8-16/h1-10,18H,11-15H2,(H2,21,22,24,25) VVQSDIAXLRLSBM-UHFFFAOYSA-N 50079165 1-Benzoyl-3-(1-benzyl-piperidin-4-yl)-urea::CHEMBL327310 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21465540 103971485 CHEMBL327310 ZINC13799179 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138486 CCc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1ccccc1 InChI=1S/C23H27N3O/c1-2-21-22(19-11-7-4-8-12-19)24-23(27)26(21)20-13-15-25(16-14-20)17-18-9-5-3-6-10-18/h3-12,20H,2,13-17H2,1H3,(H,24,27) WTYNOFOXDOHJBE-UHFFFAOYSA-N 50079169 1-(1-Benzyl-piperidin-4-yl)-5-ethyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL91498 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522614 103971489 CHEMBL91498 ZINC13799193 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138489 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1ccccc1Cl InChI=1S/C22H24ClN3O/c1-16-21(19-9-5-6-10-20(19)23)24-22(27)26(16)18-11-13-25(14-12-18)15-17-7-3-2-4-8-17/h2-10,18H,11-15H2,1H3,(H,24,27) BQYLCESBRUFPJL-UHFFFAOYSA-N 50079164 1-(1-Benzyl-piperidin-4-yl)-4-(2-chloro-phenyl)-5-methyl-1,3-dihydro-imidazol-2-one::CHEMBL89971 D(2) dopamine receptor Homo sapiens 38 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079164&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809899 103971484 CHEMBL89971 ZINC13799202 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138490 O=C(NC1CCN(Cc2ccccc2)CC1)Nc1ccccc1 InChI=1S/C19H23N3O/c23-19(20-17-9-5-2-6-10-17)21-18-11-13-22(14-12-18)15-16-7-3-1-4-8-16/h1-10,18H,11-15H2,(H2,20,21,23) FBRUCPZAISLOOV-UHFFFAOYSA-N 50079170 1-(1-Benzyl-piperidin-4-yl)-3-phenyl-urea::CHEMBL91621::US11116757, No. B20 D(2) dopamine receptor Homo sapiens 86 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4064342 103971490 CHEMBL91621 ZINC12505286 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138491 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1ccccc1 InChI=1S/C22H25N3O/c1-17-21(19-10-6-3-7-11-19)23-22(26)25(17)20-12-14-24(15-13-20)16-18-8-4-2-5-9-18/h2-11,20H,12-16H2,1H3,(H,23,26) BATHQYAQIQGDNM-UHFFFAOYSA-N 50079173 1-(1-Benzyl-piperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL91162 D(2) dopamine receptor Homo sapiens 56 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9950165 103971493 CHEMBL91162 ZINC00019659 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138492 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1cccc(Cl)c1 InChI=1S/C22H24ClN3O/c1-16-21(18-8-5-9-19(23)14-18)24-22(27)26(16)20-10-12-25(13-11-20)15-17-6-3-2-4-7-17/h2-9,14,20H,10-13,15H2,1H3,(H,24,27) UUTGTTDZMUFZGA-UHFFFAOYSA-N 50079157 1-(1-Benzyl-piperidin-4-yl)-4-(3-chloro-phenyl)-5-methyl-1,3-dihydro-imidazol-2-one::CHEMBL94283 D(2) dopamine receptor Homo sapiens 73 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079157&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643589 103971477 CHEMBL94283 ZINC13799200 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138503 O=C(NC1CCN(Cc2ccccc2)CC1)Nc1ccccn1 InChI=1S/C18H22N4O/c23-18(21-17-8-4-5-11-19-17)20-16-9-12-22(13-10-16)14-15-6-2-1-3-7-15/h1-8,11,16H,9-10,12-14H2,(H2,19,20,21,23) HHAUXZNBXXZIOV-UHFFFAOYSA-N 50079160 1-(1-Benzyl-piperidin-4-yl)-3-pyridin-2-yl-urea::CHEMBL91272 D(2) dopamine receptor Homo sapiens 190 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079160&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10852461 103971480 CHEMBL91272 ZINC13799189 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136419 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H19F3N4O3S/c1-25-8-10-26(11-9-25)18-14-12-13(29-30(27,28)19(20,21)22)6-7-15(14)23-16-4-2-3-5-17(16)24-18/h2-7,12,23H,8-11H2,1H3 XKXPMSXRABANAG-UHFFFAOYSA-N 50061559 CHEMBL72292::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-yl ester D(2) dopamine receptor Homo sapiens 140 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9954899 103957121 CHEMBL72292 ZINC14299681 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136424 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H18F3N3O4S/c1-24-8-10-25(11-9-24)18-14-12-13(29-30(26,27)19(20,21)22)6-7-16(14)28-17-5-3-2-4-15(17)23-18/h2-7,12H,8-11H2,1H3 DQNCRNVCBHYBQP-UHFFFAOYSA-N 50078062 CHEMBL430798::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepin-2-yl ester D(2) dopamine receptor Homo sapiens 52 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078062&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026300 103970697 CHEMBL430798 ZINC14299682 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136437 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H18ClF3N4O3S/c1-26-6-8-27(9-7-26)18-14-11-13(30-31(28,29)19(21,22)23)3-5-15(14)24-16-4-2-12(20)10-17(16)25-18/h2-5,10-11,24H,6-9H2,1H3 MTKHCEFATKQYMK-UHFFFAOYSA-N 50078063 CHEMBL70319::Trifluoro-methanesulfonic acid 8-chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-yl ester D(2) dopamine receptor Homo sapiens 30 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078063&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10412646 103970698 CHEMBL70319 ZINC14114286 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136445 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Homo sapiens 34 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136446 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(OS(C)(=O)=O)cc12 InChI=1S/C19H21N3O4S/c1-21-9-11-22(12-10-21)19-15-13-14(26-27(2,23)24)7-8-17(15)25-18-6-4-3-5-16(18)20-19/h3-8,13H,9-12H2,1-2H3 LUZGPEPGAGXEQF-UHFFFAOYSA-N 50078064 CHEMBL306474::Methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepin-2-yl ester D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078064&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596380 103970699 CHEMBL306474 ZINC13798272 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136457 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 4.9 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138505 Cc1c([nH]c(=O)n1C1CCN(CCCc2ccccc2)CC1)-c1ccccc1 InChI=1S/C24H29N3O/c1-19-23(21-12-6-3-7-13-21)25-24(28)27(19)22-14-17-26(18-15-22)16-8-11-20-9-4-2-5-10-20/h2-7,9-10,12-13,22H,8,11,14-18H2,1H3,(H,25,28) CRYGIUKJRPGSDW-UHFFFAOYSA-N 50079156 5-Methyl-4-phenyl-1-[1-(3-phenyl-propyl)-piperidin-4-yl]-1,3-dihydro-imidazol-2-one::CHEMBL327176 D(2) dopamine receptor Homo sapiens 330 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079156&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10667201 103971476 CHEMBL327176 ZINC13799229 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138507 Cc1c(-c2ccccc2)n(-c2ccccc2)c(=O)n1C1CCN(Cc2ccccc2)CC1 InChI=1S/C28H29N3O/c1-22-27(24-13-7-3-8-14-24)31(25-15-9-4-10-16-25)28(32)30(22)26-17-19-29(20-18-26)21-23-11-5-2-6-12-23/h2-16,26H,17-21H2,1H3 JICSUTQEGNUBOG-UHFFFAOYSA-N 50079179 1-(1-Benzyl-piperidin-4-yl)-5-methyl-3,4-diphenyl-1,3-dihydro-imidazol-2-one::CHEMBL93432 D(2) dopamine receptor Homo sapiens 8.8 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574303 103971499 CHEMBL93432 ZINC13799197 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138514 O=c1[nH]c(cn1C1CCN(Cc2ccccc2)CC1)-c1ccccc1 InChI=1S/C21H23N3O/c25-21-22-20(18-9-5-2-6-10-18)16-24(21)19-11-13-23(14-12-19)15-17-7-3-1-4-8-17/h1-10,16,19H,11-15H2,(H,22,25) ULAAUNIOEAKYBR-UHFFFAOYSA-N 50079154 1-(1-Benzyl-piperidin-4-yl)-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL93958 D(2) dopamine receptor Homo sapiens 82 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079154&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10735405 103971474 CHEMBL93958 ZINC00019661 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138522 Cc1c(-c2ccccc2)n(C)c(=O)n1C1CCN(Cc2ccccc2)CC1 InChI=1S/C23H27N3O/c1-18-22(20-11-7-4-8-12-20)24(2)23(27)26(18)21-13-15-25(16-14-21)17-19-9-5-3-6-10-19/h3-12,21H,13-17H2,1-2H3 BXEHOLVBINGZIE-UHFFFAOYSA-N 50079181 1-(1-Benzyl-piperidin-4-yl)-3,5-dimethyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL328739 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594764 103971501 CHEMBL328739 ZINC00592273 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138523 O=C(NC1CCN(Cc2ccccc2)CC1)Nc1nccc2ccccc12 InChI=1S/C22H24N4O/c27-22(25-21-20-9-5-4-8-18(20)10-13-23-21)24-19-11-14-26(15-12-19)16-17-6-2-1-3-7-17/h1-10,13,19H,11-12,14-16H2,(H2,23,24,25,27) FDQXLORJWMWFGU-UHFFFAOYSA-N 50079166 1-(1-Benzyl-piperidin-4-yl)-3-isoquinolin-1-yl-urea::CHEMBL328667 D(2) dopamine receptor Homo sapiens 150 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10546453 103971486 CHEMBL328667 ZINC12356218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138524 Cc1c(noc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C23H25ClN2O/c1-17-22(25-27-23(17)20-7-9-21(24)10-8-20)19-12-15-26(16-13-19)14-11-18-5-3-2-4-6-18/h2-10,19H,11-16H2,1H3 QDMAKDIDFJTXEL-UHFFFAOYSA-N 50050476 4-[5-(4-Chloro-phenyl)-4-methyl-isoxazol-3-yl]-1-phenethyl-piperidine::4-[5-(4-Chloro-phenyl)-4-methyl-isoxazol-3-yl]-1-phenethyl-piperidine (L-741742)::CHEMBL444309::L-741742 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133008 103947646 CHEMBL444309 3302 ZINC00602172 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138527 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1ccccn1 InChI=1S/C21H24N4O/c1-16-20(19-9-5-6-12-22-19)23-21(26)25(16)18-10-13-24(14-11-18)15-17-7-3-2-4-8-17/h2-9,12,18H,10-11,13-15H2,1H3,(H,23,26) HCOQJKDXIVIYQF-UHFFFAOYSA-N 50079167 1-(1-Benzyl-piperidin-4-yl)-5-methyl-4-pyridin-2-yl-1,3-dihydro-imidazol-2-one::CHEMBL91553 D(2) dopamine receptor Homo sapiens 270 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079167&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593869 103971487 CHEMBL91553 ZINC13799216 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138528 Cc1[nH]c(=O)n(C2CCN(Cc3ccccc3)CC2)c1-c1ccccc1 InChI=1S/C22H25N3O/c1-17-21(19-10-6-3-7-11-19)25(22(26)23-17)20-12-14-24(15-13-20)16-18-8-4-2-5-9-18/h2-11,20H,12-16H2,1H3,(H,23,26) ONVAFCPNRHAADQ-UHFFFAOYSA-N 50079178 1-(1-Benzyl-piperidin-4-yl)-4-methyl-5-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL91821 D(2) dopamine receptor Homo sapiens 280 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10569690 103971498 CHEMBL91821 ZINC00019660 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138529 Cc1c([nH]c(=O)n1C1CCN(CCc2ccccc2)CC1)-c1ccccc1 InChI=1S/C23H27N3O/c1-18-22(20-10-6-3-7-11-20)24-23(27)26(18)21-13-16-25(17-14-21)15-12-19-8-4-2-5-9-19/h2-11,21H,12-17H2,1H3,(H,24,27) GIYXEZZPINFSPU-UHFFFAOYSA-N 50079177 5-Methyl-1-(1-phenethyl-piperidin-4-yl)-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL91229 D(2) dopamine receptor Homo sapiens 220 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522613 103971497 CHEMBL91229 ZINC00592274 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138534 O=C(NCc1ccccc1)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H25N3O/c24-20(21-15-17-7-3-1-4-8-17)22-19-11-13-23(14-12-19)16-18-9-5-2-6-10-18/h1-10,19H,11-16H2,(H2,21,22,24) SEMGUZQVJIXJHC-UHFFFAOYSA-N 50079180 1-Benzyl-3-(1-benzyl-piperidin-4-yl)-urea::CHEMBL327339 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079180&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17987129 103971500 CHEMBL327339 ZINC13799185 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138539 Cc1c([nH]c(=O)n1C1CCN(Cc2ccc(Cl)cc2)CC1)-c1ccccc1 InChI=1S/C22H24ClN3O/c1-16-21(18-5-3-2-4-6-18)24-22(27)26(16)20-11-13-25(14-12-20)15-17-7-9-19(23)10-8-17/h2-10,20H,11-15H2,1H3,(H,24,27) FNWIXECQKCBEDQ-UHFFFAOYSA-N 50079172 1-[1-(4-Chloro-benzyl)-piperidin-4-yl]-5-methyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL93969 D(2) dopamine receptor Homo sapiens 60 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10762432 103971492 CHEMBL93969 ZINC13799240 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138541 CN1CCC(CC1)n1c(C)c([nH]c1=O)-c1ccccc1 InChI=1S/C16H21N3O/c1-12-15(13-6-4-3-5-7-13)17-16(20)19(12)14-8-10-18(2)11-9-14/h3-7,14H,8-11H2,1-2H3,(H,17,20) NTTKBDRKKNQJKU-UHFFFAOYSA-N 50079168 5-Methyl-1-(1-methyl-piperidin-4-yl)-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL90711 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10492351 103971488 CHEMBL90711 ZINC13799220 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138542 Cc1c([nH]c(=O)n1C1CCN(Cc2cccc(Cl)c2)CC1)-c1ccccc1 InChI=1S/C22H24ClN3O/c1-16-21(18-7-3-2-4-8-18)24-22(27)26(16)20-10-12-25(13-11-20)15-17-6-5-9-19(23)14-17/h2-9,14,20H,10-13,15H2,1H3,(H,24,27) PDJMURIRAHUSPJ-UHFFFAOYSA-N 50079175 1-[1-(3-Chloro-benzyl)-piperidin-4-yl]-5-methyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL93832 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10667579 103971495 CHEMBL93832 ZINC13799236 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138543 Cc1c([nH]c(=O)n1C1CCN(Cc2cccc(c2)C#N)CC1)-c1ccccc1 InChI=1S/C23H24N4O/c1-17-22(20-8-3-2-4-9-20)25-23(28)27(17)21-10-12-26(13-11-21)16-19-7-5-6-18(14-19)15-24/h2-9,14,21H,10-13,16H2,1H3,(H,25,28) JLSSZJJVQVSQHQ-UHFFFAOYSA-N 50079171 3-[4-(5-Methyl-2-oxo-4-phenyl-2,3-dihydro-imidazol-1-yl)-piperidin-1-ylmethyl]-benzonitrile::CHEMBL431095 D(2) dopamine receptor Homo sapiens >1900 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10248715 103971491 CHEMBL431095 ZINC01490296 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138550 Cc1c([nH]c(=O)n1C1CCN(CC2CCCCC2)CC1)-c1ccccc1 InChI=1S/C22H31N3O/c1-17-21(19-10-6-3-7-11-19)23-22(26)25(17)20-12-14-24(15-13-20)16-18-8-4-2-5-9-18/h3,6-7,10-11,18,20H,2,4-5,8-9,12-16H2,1H3,(H,23,26) VFLJXRCSXJBPAE-UHFFFAOYSA-N 50079174 1-(1-Cyclohexylmethyl-piperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL316125 D(2) dopamine receptor Homo sapiens 83 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10570080 103971494 CHEMBL316125 ZINC13799224 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138554 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2)CC1)-c1cccs1 InChI=1S/C20H23N3OS/c1-15-19(18-8-5-13-25-18)21-20(24)23(15)17-9-11-22(12-10-17)14-16-6-3-2-4-7-16/h2-8,13,17H,9-12,14H2,1H3,(H,21,24) OEJDOSDQLNSUBL-UHFFFAOYSA-N 50079182 1-(1-Benzyl-piperidin-4-yl)-5-methyl-4-thiophen-2-yl-1,3-dihydro-imidazol-2-one::CHEMBL90005 D(2) dopamine receptor Homo sapiens 7.8 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594242 103971502 CHEMBL90005 ZINC12356159 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138557 Cc1c([nH]c(=O)n1C1CCN(Cc2ccccc2Cl)CC1)-c1ccccc1 InChI=1S/C22H24ClN3O/c1-16-21(17-7-3-2-4-8-17)24-22(27)26(16)19-11-13-25(14-12-19)15-18-9-5-6-10-20(18)23/h2-10,19H,11-15H2,1H3,(H,24,27) GSMUFGQPDDQGFK-UHFFFAOYSA-N 50079163 1-[1-(2-Chloro-benzyl)-piperidin-4-yl]-5-methyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL93970 D(2) dopamine receptor Homo sapiens >1500 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079163&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571927 103971483 CHEMBL93970 ZINC13799232 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50138558 COc1ccc(cc1)-c1[nH]c(=O)n(C2CCN(Cc3ccccc3)CC2)c1C InChI=1S/C23H27N3O2/c1-17-22(19-8-10-21(28-2)11-9-19)24-23(27)26(17)20-12-14-25(15-13-20)16-18-6-4-3-5-7-18/h3-11,20H,12-16H2,1-2H3,(H,24,27) JSOOBIHCFROWDG-UHFFFAOYSA-N 50079176 1-(1-Benzyl-piperidin-4-yl)-4-(4-methoxy-phenyl)-5-methyl-1,3-dihydro-imidazol-2-one::CHEMBL450021 D(2) dopamine receptor Homo sapiens 110 ChEMBL 10.1021/jm991029k 10.7270/Q2P55MPV 10411491 Carling, RW; Moore, KW; Moyes, CR; Jones, EA; Bonner, K; Emms, F; Marwood, R; Patel, S; Patel, S; Fletcher, AE; Beer, M; Sohal, B; Pike, A; Leeson, PD Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10619612 103971496 CHEMBL450021 ZINC13799205 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136507 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 260 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136515 CN1CCN(CC1)C1=Nc2ccccc2Sc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H18F3N3O3S2/c1-24-8-10-25(11-9-24)18-14-12-13(28-30(26,27)19(20,21)22)6-7-16(14)29-17-5-3-2-4-15(17)23-18/h2-7,12H,8-11H2,1H3 PZIGTEKDSRHYIT-UHFFFAOYSA-N 50078061 CHEMBL73589::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepin-2-yl ester D(2) dopamine receptor Homo sapiens 23 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10049758 103970696 CHEMBL73589 ZINC14299683 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009747 Clc1ccc(cc1)N1CCN(Cc2cc[nH]c2C=C(C#N)C#N)CC1 InChI=1S/C19H18ClN5/c20-17-1-3-18(4-2-17)25-9-7-24(8-10-25)14-16-5-6-23-19(16)11-15(12-21)13-22/h1-6,11,23H,7-10,14H2 RCACIEKJQOIDQV-UHFFFAOYSA-N 50079641 2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile::CHEMBL300553 D(2) dopamine receptor Homo sapiens 15000 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467373 103971783 CHEMBL300553 ZINC36216457 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009748 Clc1ccc(cc1)N1CCN(Cc2ccc(C=C(C#N)C#N)[nH]2)CC1 InChI=1S/C19H18ClN5/c20-16-1-5-19(6-2-16)25-9-7-24(8-10-25)14-18-4-3-17(23-18)11-15(12-21)13-22/h1-6,11,23H,7-10,14H2 HEBQIUNCEBCMFD-UHFFFAOYSA-N 50079646 2-{5-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile::4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-pyrrol-2-ylmethyl]-piperazin-1-ium::CHEMBL303538 D(2) dopamine receptor Homo sapiens 59000 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079646&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467370 103971788 CHEMBL303538 ZINC13862510 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009749 N#CC(=Cc1[nH]ccc1CN1CCN(CC1)c1ccccc1)C#N InChI=1S/C19H19N5/c20-13-16(14-21)12-19-17(6-7-22-19)15-23-8-10-24(11-9-23)18-4-2-1-3-5-18/h1-7,12,22H,8-11,15H2 JXPFVJLJUKGXQP-UHFFFAOYSA-N 50079643 2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL440120 D(2) dopamine receptor Homo sapiens 12750 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467372 103971785 CHEMBL440120 ZINC36216464 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009750 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009752 N#CC(=Cc1cc(CN2CCN(CC2)c2ccccc2)c[nH]1)C#N InChI=1S/C19H19N5/c20-12-16(13-21)10-18-11-17(14-22-18)15-23-6-8-24(9-7-23)19-4-2-1-3-5-19/h1-5,10-11,14,22H,6-9,15H2 FASYQPOSAUOTDU-UHFFFAOYSA-N 50079644 2-[4-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL294459 D(2) dopamine receptor Homo sapiens 975 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425969 103971786 CHEMBL294459 ZINC36216460 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50009753 Clc1ccc(cc1)N1CCN(Cc2c[nH]c(C=C(C#N)C#N)c2)CC1 InChI=1S/C19H18ClN5/c20-17-1-3-19(4-2-17)25-7-5-24(6-8-25)14-16-10-18(23-13-16)9-15(11-21)12-22/h1-4,9-10,13,23H,5-8,14H2 LGXAESURRIWEJV-UHFFFAOYSA-N 50079645 2-{4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile::4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-pyrrol-3-ylmethyl]-piperazin-1-ium::CHEMBL294458 D(2) dopamine receptor Homo sapiens 10300 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079645&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467371 103971787 CHEMBL294458 ZINC13862512 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50139359 N#CC(=Cc1ccc(CN2CCN(CC2)c2ccccc2)[nH]1)C#N InChI=1S/C19H19N5/c20-13-16(14-21)12-17-6-7-18(22-17)15-23-8-10-24(11-9-23)19-4-2-1-3-5-19/h1-7,12,22H,8-11,15H2 FMWVLGRDWGHGJV-UHFFFAOYSA-N 50079642 2-[5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL293956 D(2) dopamine receptor Homo sapiens >100000 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467369 103971784 CHEMBL293956 ZINC36216462 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136706 CCCN(CCC)C1COc2c(C1)cccc2-c1ccoc1 InChI=1S/C19H25NO2/c1-3-9-20(10-4-2)17-12-15-6-5-7-18(19(15)22-14-17)16-8-11-21-13-16/h5-8,11,13,17H,3-4,9-10,12,14H2,1-2H3 PYRDKFKAOMQLLU-UHFFFAOYSA-N 50078241 (8-Furan-3-yl-chroman-3-yl)-dipropyl-amine::CHEMBL38580 D(2) dopamine receptor Homo sapiens 48 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286891 103970838 CHEMBL38580 ZINC29330776 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136709 CCCN(CCC)C1COc2c(C1)cccc2C(=O)c1ccccc1 InChI=1S/C22H27NO2/c1-3-13-23(14-4-2)19-15-18-11-8-12-20(22(18)25-16-19)21(24)17-9-6-5-7-10-17/h5-12,19H,3-4,13-16H2,1-2H3 GUEHAKSGYHUPRR-UHFFFAOYSA-N 50078244 (3-Dipropylamino-chroman-8-yl)-phenyl-methanone::CHEMBL42857 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078244&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287274 103970841 CHEMBL42857 ZINC29343685 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136711 CCCN(CCC)C1COc2c(C1)cccc2C(=O)c1ccoc1 InChI=1S/C20H25NO3/c1-3-9-21(10-4-2)17-12-15-6-5-7-18(20(15)24-14-17)19(22)16-8-11-23-13-16/h5-8,11,13,17H,3-4,9-10,12,14H2,1-2H3 VZQTUQHHRRWIAE-UHFFFAOYSA-N 50078246 (3-Dipropylamino-chroman-8-yl)-furan-3-yl-methanone::CHEMBL38656 D(2) dopamine receptor Homo sapiens 1360 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287224 103970843 CHEMBL38656 ZINC29334202 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136712 CCCN(CCC)C1COc2c(C1)cccc2C(=O)c1ccc(cc1)C(C)=O InChI=1S/C24H29NO3/c1-4-13-25(14-5-2)21-15-20-7-6-8-22(24(20)28-16-21)23(27)19-11-9-18(10-12-19)17(3)26/h6-12,21H,4-5,13-16H2,1-3H3 GDCQIEHJIRJTNW-UHFFFAOYSA-N 50078247 1-[4-(3-Dipropylamino-chroman-8-carbonyl)-phenyl]-ethanone::CHEMBL43359 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286909 103970844 CHEMBL43359 ZINC29341139 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136713 CCCN(CCC)C1COc2c(C1)cccc2-c1ccc(cc1)C(F)(F)F InChI=1S/C22H26F3NO/c1-3-12-26(13-4-2)19-14-17-6-5-7-20(21(17)27-15-19)16-8-10-18(11-9-16)22(23,24)25/h5-11,19H,3-4,12-15H2,1-2H3 OSFSWZUCOBPVDJ-UHFFFAOYSA-N 50078248 CHEMBL43073::Dipropyl-(8-thiophen-3-yl-chroman-3-yl)-amine D(2) dopamine receptor Homo sapiens 763 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286901 103970845 CHEMBL43073 ZINC29338395 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136714 CCCN(CCC)C1COc2c(O)cccc2C1 InChI=1S/C15H23NO2/c1-3-8-16(9-4-2)13-10-12-6-5-7-14(17)15(12)18-11-13/h5-7,13,17H,3-4,8-11H2,1-2H3 PXSSMALRVSYAFM-UHFFFAOYSA-N 50020220 3-Dipropylamino-chroman-8-ol::CHEMBL38428 D(2) dopamine receptor Homo sapiens 128 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020220&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86131 103931134 CHEMBL38428 ZINC05647678 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136715 CCCN(CCC)C1COc2c(C1)cccc2C(=O)c1ccsc1 InChI=1S/C20H25NO2S/c1-3-9-21(10-4-2)17-12-15-6-5-7-18(20(15)23-13-17)19(22)16-8-11-24-14-16/h5-8,11,14,17H,3-4,9-10,12-13H2,1-2H3 LUQBYFOXFQWXND-UHFFFAOYSA-N 50078245 (3-Dipropylamino-chroman-8-yl)-thiophen-3-yl-methanone::CHEMBL38855 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287238 103970842 CHEMBL38855 ZINC29336345 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136718 CCCN(CCC)C1COc2c(C1)cccc2-c1ccccc1 InChI=1S/C21H27NO/c1-3-13-22(14-4-2)19-15-18-11-8-12-20(21(18)23-16-19)17-9-6-5-7-10-17/h5-12,19H,3-4,13-16H2,1-2H3 OYEKUFKQGCYWCG-UHFFFAOYSA-N 50078243 (8-Phenyl-chroman-3-yl)-dipropyl-amine::CHEMBL41134 D(2) dopamine receptor Homo sapiens 590 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9972630 103970840 CHEMBL41134 ZINC29340333 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135652 COc1ccc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2n1 InChI=1S/C17H18N2O3/c1-22-16-5-3-10-13(19-16)8-18-12-4-2-9-6-14(20)15(21)7-11(9)17(10)12/h3,5-7,12,17-18,20-21H,2,4,8H2,1H3/t12-,17-/m1/s1 IBBZFQYJQGDOGF-SJKOYZFVSA-N 50077631 (6aR,12bS)-3-Methoxy-5,6,6a,7,8,12b-hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL285924 D(2) dopamine receptor Homo sapiens 520 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077631&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276552 103970399 CHEMBL285924 ZINC28763876 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135653 Cc1cc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2nc1C InChI=1S/C18H20N2O2/c1-9-5-13-15(20-10(9)2)8-19-14-4-3-11-6-16(21)17(22)7-12(11)18(13)14/h5-7,14,18-19,21-22H,3-4,8H2,1-2H3/t14-,18+/m1/s1 QSFCVDVZBPPRDF-KDOFPFPSSA-N 50077632 (6aR,12bS)-2,3-Dimethyl-5,6,6a,7,8,12b-hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL284959 D(2) dopamine receptor Homo sapiens 9100 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276651 103970400 CHEMBL284959 ZINC28765741 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135656 Oc1cc2CC[C@H]3NCc4cnccc4[C@@H]3c2cc1O InChI=1S/C16H16N2O2/c19-14-5-9-1-2-13-16(12(9)6-15(14)20)11-3-4-17-7-10(11)8-18-13/h3-7,13,16,18-20H,1-2,8H2/t13-,16-/m1/s1 USNRFQBPPPITNX-CZUORRHYSA-N 50077636 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-3,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL284644 D(2) dopamine receptor Homo sapiens 4400 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276556 103970404 CHEMBL284644 ZINC28763688 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135661 Oc1cc2CC[C@H]3NCc4ncccc4[C@@H]3c2cc1O InChI=1S/C16H16N2O2/c19-14-6-9-3-4-12-16(11(9)7-15(14)20)10-2-1-5-17-13(10)8-18-12/h1-2,5-7,12,16,18-20H,3-4,8H2/t12-,16-/m1/s1 ZFSVGJPKLUWVIK-MLGOLLRUSA-N 50077638 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL281932 D(2) dopamine receptor Homo sapiens 2500 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015860 103970406 CHEMBL281932 ZINC28763645 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135665 Cc1cncc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc12 InChI=1S/C17H18N2O2/c1-9-6-18-7-13-12(9)8-19-14-3-2-10-4-15(20)16(21)5-11(10)17(13)14/h4-7,14,17,19-21H,2-3,8H2,1H3/t14-,17+/m1/s1 AUENKTRXUKDSTC-PBHICJAKSA-N 50077640 (6aR,12bS)-4-Methyl-5,6,6a,7,8,12b-hexahydro-2,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL282136 D(2) dopamine receptor Homo sapiens 400 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276557 103970408 CHEMBL282136 ZINC28763814 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135667 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Homo sapiens 1520 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135670 CCCCc1cnc2CN[C@@H]3CCc4cc(O)c(O)cc4[C@H]3c2c1 InChI=1S/C20H24N2O2/c1-2-3-4-12-7-15-17(21-10-12)11-22-16-6-5-13-8-18(23)19(24)9-14(13)20(15)16/h7-10,16,20,22-24H,2-6,11H2,1H3/t16-,20+/m1/s1 LEWWBJBGGUZKQX-UZLBHIALSA-N 50077642 (6aR,12bS)-2-Butyl-5,6,6a,7,8,12b-hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL283247 D(2) dopamine receptor Homo sapiens 1900 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276652 103970410 CHEMBL283247 ZINC28765743 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135671 Cc1cnc2CN[C@@H]3CCc4cc(O)c(O)cc4[C@H]3c2c1 InChI=1S/C17H18N2O2/c1-9-4-12-14(18-7-9)8-19-13-3-2-10-5-15(20)16(21)6-11(10)17(12)13/h4-7,13,17,19-21H,2-3,8H2,1H3/t13-,17+/m1/s1 OTRPXYDXEWMYIL-DYVFJYSZSA-N 50077641 (6aR,12bS)-2-Methyl-5,6,6a,7,8,12b-hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL275379 D(2) dopamine receptor Homo sapiens 12000 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276535 103970409 CHEMBL275379 ZINC28764181 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135673 Oc1cc2CC[C@H]3NCc4ccncc4[C@@H]3c2cc1O InChI=1S/C16H16N2O2/c19-14-5-9-1-2-13-16(11(9)6-15(14)20)12-8-17-4-3-10(12)7-18-13/h3-6,8,13,16,18-20H,1-2,7H2/t13-,16+/m1/s1 WYHAAMMHWQPLAP-CJNGLKHVSA-N 50077643 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-2,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL28054 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276404 103970411 CHEMBL28054 ZINC28763854 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135674 CCCc1cc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C18H21NO2S/c1-2-3-11-7-13-17(22-11)9-19-14-5-4-10-6-15(20)16(21)8-12(10)18(13)14/h6-8,14,18-21H,2-5,9H2,1H3/t14-,18+/m1/s1 REHAKLRYABHSQJ-KDOFPFPSSA-N 50033114 (5aR,11bS)-2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::A-86929::CHEMBL28338 D(2) dopamine receptor Homo sapiens 710 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033114&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9841398 103941455 CHEMBL28338 ZINC00019656 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135678 Cc1ccc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2n1 InChI=1S/C17H18N2O2/c1-9-2-4-11-14(19-9)8-18-13-5-3-10-6-15(20)16(21)7-12(10)17(11)13/h2,4,6-7,13,17-18,20-21H,3,5,8H2,1H3/t13-,17-/m1/s1 QHOJNFIJAUDAJD-CXAGYDPISA-N 50077639 (6aR,12bS)-3-Methyl-5,6,6a,7,8,12b-hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL27117 D(2) dopamine receptor Homo sapiens 1400 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276412 103970407 CHEMBL27117 ZINC28762993 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135685 CCCc1ccc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2n1 InChI=1S/C19H22N2O2/c1-2-3-12-5-6-13-16(21-12)10-20-15-7-4-11-8-17(22)18(23)9-14(11)19(13)15/h5-6,8-9,15,19-20,22-23H,2-4,7,10H2,1H3/t15-,19-/m1/s1 KBXQAHKIUBTDCL-DNVCBOLYSA-N 50077634 (6aR,12bS)-3-Propyl-5,6,6a,7,8,12b-hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL26965 D(2) dopamine receptor Homo sapiens 450 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276551 103970402 CHEMBL26965 ZINC28764223 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135692 Oc1cc2CC[C@H]3NCc4nc(F)ccc4[C@@H]3c2cc1O InChI=1S/C16H15FN2O2/c17-15-4-2-9-12(19-15)7-18-11-3-1-8-5-13(20)14(21)6-10(8)16(9)11/h2,4-6,11,16,18,20-21H,1,3,7H2/t11-,16-/m1/s1 UVPIZMCLGBXZAJ-BDJLRTHQSA-N 50077635 (6aR,12bS)-3-Fluoro-5,6,6a,7,8,12b-hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL27101 D(2) dopamine receptor Homo sapiens 2200 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276414 103970403 CHEMBL27101 ZINC28763201 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135695 Oc1cc2CC[C@H]3NCc4c(F)cncc4[C@@H]3c2cc1O InChI=1S/C16H15FN2O2/c17-12-7-18-5-11-10(12)6-19-13-2-1-8-3-14(20)15(21)4-9(8)16(11)13/h3-5,7,13,16,19-21H,1-2,6H2/t13-,16+/m1/s1 DPWOYQPDXBTFJT-CJNGLKHVSA-N 50077633 (6aR,12bS)-4-Fluoro-5,6,6a,7,8,12b-hexahydro-2,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL26365 D(2) dopamine receptor Homo sapiens 890 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276572 103970401 CHEMBL26365 ZINC28764795 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50135696 Oc1cc2CC[C@H]3NCc4nc5CCCCc5cc4[C@@H]3c2cc1O InChI=1S/C20H22N2O2/c23-18-8-11-5-6-16-20(13(11)9-19(18)24)14-7-12-3-1-2-4-15(12)22-17(14)10-21-16/h7-9,16,20-21,23-24H,1-6,10H2/t16-,20+/m1/s1 BDRPLVMDSVQGDO-UZLBHIALSA-N 50077637 (6aR,14bS)-5,6,6a,7,8,10,11,12,13,14b-Decahydro-7,9-diaza-naphtho[1,2-a]anthracene-2,3-diol::CHEMBL287513 D(2) dopamine receptor Homo sapiens 3600 ChEMBL 10.1016/s0960-894x(99)00214-0 10.7270/Q2S75FH5 10360732 Gu, YG; Bayburt, EK; Michaelides, MR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276405 103970405 CHEMBL287513 ZINC28763855 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136721 CCCN(CCC)C1COc2c(C1)cccc2C(=O)c1ccc(OC)cc1 InChI=1S/C23H29NO3/c1-4-13-24(14-5-2)19-15-18-7-6-8-21(23(18)27-16-19)22(25)17-9-11-20(26-3)12-10-17/h6-12,19H,4-5,13-16H2,1-3H3 GMKQIBRZRXDXMT-UHFFFAOYSA-N 50078249 (3-Dipropylamino-chroman-8-yl)-(4-methoxy-phenyl)-methanone::CHEMBL41759 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287265 103970846 CHEMBL41759 ZINC29340984 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136722 CCCN(CCC)C1COc2c(C1)cccc2-c1ccc(OC)cc1 InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)19-15-18-7-6-8-21(22(18)25-16-19)17-9-11-20(24-3)12-10-17/h6-12,19H,4-5,13-16H2,1-3H3 QWKYFMXJKILTAJ-UHFFFAOYSA-N 50078240 CHEMBL41200::[8-(4-Methoxy-phenyl)-chroman-3-yl]-dipropyl-amine D(2) dopamine receptor Homo sapiens 1090 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287035 103970837 CHEMBL41200 ZINC29338487 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136723 CCCN(CCC)C1COc2c(C1)cccc2-c1ccsc1 InChI=1S/C19H25NOS/c1-3-9-20(10-4-2)17-12-15-6-5-7-18(19(15)21-13-17)16-8-11-22-14-16/h5-8,11,14,17H,3-4,9-10,12-13H2,1-2H3 VKTALASDYHQYCC-UHFFFAOYSA-N 50078250 CHEMBL39847::Dipropyl-(8-thiophen-3-yl-chroman-3-yl)-amine D(2) dopamine receptor Homo sapiens 398 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287333 103970847 CHEMBL39847 ZINC29328761 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136724 CCCN(CCC)C1COc2cccc(O)c2C1 InChI=1S/C15H23NO2/c1-3-8-16(9-4-2)12-10-13-14(17)6-5-7-15(13)18-11-12/h5-7,12,17H,3-4,8-11H2,1-2H3 QPVJRLOTNHJYTL-UHFFFAOYSA-N 50036864 3-Dipropylamino-chroman-5-ol::CHEMBL27995 D(2) dopamine receptor Homo sapiens >3000 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131001 103944505 CHEMBL27995 ZINC05833031 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136725 CCCN(CCC)C1COc2c(C1)cccc2-c1ccccc1OC InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)18-15-17-9-8-11-20(22(17)25-16-18)19-10-6-7-12-21(19)24-3/h6-12,18H,4-5,13-16H2,1-3H3 VDFXNGPWAIBQSN-UHFFFAOYSA-N 50078242 CHEMBL41491::[8-(2-Methoxy-phenyl)-chroman-3-yl]-dipropyl-amine D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078242&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287180 103970839 CHEMBL41491 ZINC13581261 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136726 CCCN(CCC)C1COc2c(C1)cccc2C(=O)c1ccccc1OC InChI=1S/C23H29NO3/c1-4-13-24(14-5-2)18-15-17-9-8-11-20(23(17)27-16-18)22(25)19-10-6-7-12-21(19)26-3/h6-12,18H,4-5,13-16H2,1-3H3 LSRCVTDWTWEDND-UHFFFAOYSA-N 50078252 (3-Dipropylamino-chroman-8-yl)-(2-methoxy-phenyl)-methanone::CHEMBL291251 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287301 103970849 CHEMBL291251 ZINC29342696 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50136728 CCCN(CCC)C1COc2c(C1)cccc2C(=O)c1ccc(cc1)C(F)(F)F InChI=1S/C23H26F3NO2/c1-3-12-27(13-4-2)19-14-17-6-5-7-20(22(17)29-15-19)21(28)16-8-10-18(11-9-16)23(24,25)26/h5-11,19H,3-4,12-15H2,1-2H3 ONJLWYBUUWLSBG-UHFFFAOYSA-N 50078251 (3-Dipropylamino-chroman-8-yl)-(4-trifluoromethyl-phenyl)-methanone::CHEMBL41120 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(99)00232-2 10.7270/Q2T152TW 10386940 Caldirola, P; Chowdhury, R; Unelius, L; Mohell, N; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286910 103970848 CHEMBL41120 ZINC29341511 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142147 FC(F)(F)c1nc2c(OCCNCc3ccccc3)cc(Cl)cc2[nH]1 InChI=1S/C17H15ClF3N3O/c18-12-8-13-15(24-16(23-13)17(19,20)21)14(9-12)25-7-6-22-10-11-4-2-1-3-5-11/h1-5,8-9,22H,6-7,10H2,(H,23,24) MMZIPJNBJQJCBM-UHFFFAOYSA-N 50081105 Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL86504 D(2) dopamine receptor Homo sapiens 32 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081105&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820680 103981159 CHEMBL86504 ZINC03926703 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142150 Oc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2 VBTFJGYCISLKEQ-UHFFFAOYSA-N 50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508 D(2) dopamine receptor Homo sapiens 76 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776546 103963876 CHEMBL64508 ZINC12355952 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142154 C(COc1cccc2[nH]ccc12)NCc1ccccc1 InChI=1S/C17H18N2O/c1-2-5-14(6-3-1)13-18-11-12-20-17-8-4-7-16-15(17)9-10-19-16/h1-10,18-19H,11-13H2 ZEHDEZWEFBOGNZ-UHFFFAOYSA-N 50077576 Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine::CHEMBL64283 D(2) dopamine receptor Homo sapiens 82 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9838216 103970345 CHEMBL64283 ZINC01903142 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142162 Cc1nc2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C17H19N3O/c1-13-19-15-8-5-9-16(17(15)20-13)21-11-10-18-12-14-6-3-2-4-7-14/h2-9,18H,10-12H2,1H3,(H,19,20) GGIUXVIFNJVWLE-UHFFFAOYSA-N 50081104 Benzyl-[2-(2-methyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL87067 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081104&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9925730 103981158 CHEMBL87067 ZINC26576445 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142163 FC(F)(F)c1nc2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C17H16F3N3O/c18-17(19,20)16-22-13-7-4-8-14(15(13)23-16)24-10-9-21-11-12-5-2-1-3-6-12/h1-8,21H,9-11H2,(H,22,23) BKHJHBMOHZNYEP-UHFFFAOYSA-N 50081110 Benzyl-[2-(2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL87192 D(2) dopamine receptor Homo sapiens 1.8 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081110&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840672 103981164 CHEMBL87192 ZINC03923630 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142166 O=c1[nH]c2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C16H17N3O2/c20-16-18-13-7-4-8-14(15(13)19-16)21-10-9-17-11-12-5-2-1-3-6-12/h1-8,17H,9-11H2,(H2,18,19,20) MUGIIZXLOBYZRQ-UHFFFAOYSA-N 50081112 4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazol-2-one::CHEMBL314174 D(2) dopamine receptor Homo sapiens 3.9 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081112&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817253 103981166 CHEMBL314174 ZINC02008258 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142169 O=C1Cc2c(N1)cccc2OCCNCc1ccccc1 InChI=1S/C17H18N2O2/c20-17-11-14-15(19-17)7-4-8-16(14)21-10-9-18-12-13-5-2-1-3-6-13/h1-8,18H,9-12H2,(H,19,20) CVWQKEFTSSJDLS-UHFFFAOYSA-N 50077578 4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL59752 D(2) dopamine receptor Homo sapiens 4.3 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903877 103970347 CHEMBL59752 ZINC01903144 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142178 C(COc1cccc2nc[nH]c12)NCc1ccccc1 InChI=1S/C16H17N3O/c1-2-5-13(6-3-1)11-17-9-10-20-15-8-4-7-14-16(15)19-12-18-14/h1-8,12,17H,9-11H2,(H,18,19) XQWCSGWUJUEAQM-UHFFFAOYSA-N 50081111 CHEMBL89420::[2-(1H-Benzoimidazol-4-yloxy)-ethyl]-benzyl-amine D(2) dopamine receptor Homo sapiens 86 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081111&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9881815 103981165 CHEMBL89420 ZINC26577725 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142188 Clc1cc(OCCNCc2ccccc2)c2[nH]c(=S)[nH]c2c1 InChI=1S/C16H16ClN3OS/c17-12-8-13-15(20-16(22)19-13)14(9-12)21-7-6-18-10-11-4-2-1-3-5-11/h1-5,8-9,18H,6-7,10H2,(H2,19,20,22) HMFWWORRYDWEDS-UHFFFAOYSA-N 50081107 4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazole-2-thione::CHEMBL89037 D(2) dopamine receptor Homo sapiens 6.5 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9949531 103981161 CHEMBL89037 ZINC01547101 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142190 S=c1[nH]c2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C16H17N3OS/c21-16-18-13-7-4-8-14(15(13)19-16)20-10-9-17-11-12-5-2-1-3-6-12/h1-8,17H,9-11H2,(H2,18,19,21) IMYFITBNCNWHTL-UHFFFAOYSA-N 50081108 4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazole-2-thione::CHEMBL327782 D(2) dopamine receptor Homo sapiens 3 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081108&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817774 103981162 CHEMBL327782 ZINC01547096 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142194 Clc1cc(OCCNCc2ccccc2)c2[nH]c(=O)[nH]c2c1 InChI=1S/C16H16ClN3O2/c17-12-8-13-15(20-16(21)19-13)14(9-12)22-7-6-18-10-11-4-2-1-3-5-11/h1-5,8-9,18H,6-7,10H2,(H2,19,20,21) YKNNRQLCQGQFRB-UHFFFAOYSA-N 50081106 4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazol-2-one::CHEMBL329398 D(2) dopamine receptor Homo sapiens 2.6 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081106&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861786 103981160 CHEMBL329398 ZINC02008275 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142199 C(COc1cccc2[nH]ncc12)NCc1ccccc1 InChI=1S/C16H17N3O/c1-2-5-13(6-3-1)11-17-9-10-20-16-8-4-7-15-14(16)12-18-19-15/h1-8,12,17H,9-11H2,(H,18,19) WYGBVOBBNUHWLX-UHFFFAOYSA-N 50081109 Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine::CHEMBL87137 D(2) dopamine receptor Homo sapiens 80 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081109&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816808 103981163 CHEMBL87137 ZINC03917152 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140183 CCCN(Cc1ccc(F)cc1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C21H26FNO/c1-3-13-23(15-16-7-9-18(22)10-8-16)19-11-12-20-17(14-19)5-4-6-21(20)24-2/h4-10,19H,3,11-15H2,1-2H3/t19-/m1/s1 NBGVZXIBORQZMS-LJQANCHMSA-N 50080048 (4-Fluoro-benzyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL71599 D(2) dopamine receptor Homo sapiens 43.8 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309076 103980239 CHEMBL71599 ZINC26283574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140186 CCCN(Cc1ccc(cc1)[N+]([O-])=O)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C21H26N2O3/c1-3-13-22(15-16-7-9-18(10-8-16)23(24)25)19-11-12-20-17(14-19)5-4-6-21(20)26-2/h4-10,19H,3,11-15H2,1-2H3/t19-/m1/s1 OQFVFESDHDATCZ-LJQANCHMSA-N 50080050 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-(4-nitro-benzyl)-propyl-amine::CHEMBL433121 D(2) dopamine receptor Homo sapiens 215 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9975434 103980241 CHEMBL433121 ZINC26277457 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140188 CCCN(Cc1ccccc1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C21H27NO/c1-3-14-22(16-17-8-5-4-6-9-17)19-12-13-20-18(15-19)10-7-11-21(20)23-2/h4-11,19H,3,12-16H2,1-2H3/t19-/m1/s1 JZLLENPQJVOGOX-LJQANCHMSA-N 50080051 Benzyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL68545 D(2) dopamine receptor Homo sapiens 65.6 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10063953 103980242 CHEMBL68545 ZINC26268399 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140191 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 0.16 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140192 CCCN(CCC)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-9-10-16-14(13-15)7-6-8-17(16)19-3/h6-8,15H,4-5,9-13H2,1-3H3/t15-/m1/s1 HQGWTXXZVBZBPH-OAHLLOKOSA-N 50080053 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL68573 D(2) dopamine receptor Homo sapiens 46 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308898 103980244 CHEMBL68573 ZINC13759795 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140194 CCCN(Cc1ccco1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C19H25NO2/c1-3-11-20(14-17-7-5-12-22-17)16-9-10-18-15(13-16)6-4-8-19(18)21-2/h4-8,12,16H,3,9-11,13-14H2,1-2H3/t16-/m1/s1 WAKZRNAHRQKOQJ-MRXNPFEDSA-N 50080052 CHEMBL303502::Furan-2-ylmethyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine D(2) dopamine receptor Homo sapiens 118 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309058 103980243 CHEMBL303502 ZINC26265987 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140195 COc1cccc2C[C@@H](CCc12)N(Cc1ccccc1)Cc1ccccc1 InChI=1S/C25H27NO/c1-27-25-14-8-13-22-17-23(15-16-24(22)25)26(18-20-9-4-2-5-10-20)19-21-11-6-3-7-12-21/h2-14,23H,15-19H2,1H3/t23-/m1/s1 MNNMWEOINNJPCF-HSZRJFAPSA-N 50080054 CHEMBL69705::Dibenzyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22082742 103980245 CHEMBL69705 ZINC26271634 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140198 CCCN[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C14H21NO/c1-3-9-15-12-7-8-13-11(10-12)5-4-6-14(13)16-2/h4-6,12,15H,3,7-10H2,1-2H3/t12-/m1/s1 ICJPCRXVYMMSJY-GFCCVEGCSA-N 50080055 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL71275 D(2) dopamine receptor Homo sapiens 82.3 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080055&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10656511 103980246 CHEMBL71275 ZINC13759787 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140199 COc1cccc2C[C@@H](CCc12)NCc1ccccc1 InChI=1S/C18H21NO/c1-20-18-9-5-8-15-12-16(10-11-17(15)18)19-13-14-6-3-2-4-7-14/h2-9,16,19H,10-13H2,1H3/t16-/m1/s1 OZFLGQHJVWSALN-MRXNPFEDSA-N 50080056 Benzyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine::CHEMBL65896 D(2) dopamine receptor Homo sapiens 1010 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080056&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12280565 103980247 CHEMBL65896 ZINC26265994 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140200 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 759 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140201 CCCN(CCC)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C16H24FN/c1-3-10-18(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)17/h5-7,14H,3-4,8-12H2,1-2H3/t14-/m1/s1 WFENTJXFRAVXHY-CQSZACIVSA-N 50053670 ((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine; hydrochloride::CHEMBL541858::CHEMBL69985 D(2) dopamine receptor Homo sapiens 201 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10729313 103950349 CHEMBL69985CHEMBL541858 ZINC13759323 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140203 CCCN(Cc1ccc(OC)cc1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C22H29NO2/c1-4-14-23(16-17-8-11-20(24-2)12-9-17)19-10-13-21-18(15-19)6-5-7-22(21)25-3/h5-9,11-12,19H,4,10,13-16H2,1-3H3/t19-/m1/s1 JAUQVGAQEBWHPG-LJQANCHMSA-N 50080047 (4-Methoxy-benzyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL67923 D(2) dopamine receptor Homo sapiens 22 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309005 103980238 CHEMBL67923 ZINC26279039 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140206 CCCN(Cc1ccccc1)[C@@H]1CCc2c(F)cccc2C1 InChI=1S/C20H24FN/c1-2-13-22(15-16-7-4-3-5-8-16)18-11-12-19-17(14-18)9-6-10-20(19)21/h3-10,18H,2,11-15H2,1H3/t18-/m1/s1 IZRKKTGXKLIJDE-GOSISDBHSA-N 50054337 Benzyl-((R)-5-fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL65847 D(2) dopamine receptor Homo sapiens 415.0 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402380 103950987 CHEMBL65847 ZINC13760017 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50140208 CCCN(Cc1cccs1)[C@@H]1CCc2c(C1)cccc2OC InChI=1S/C19H25NOS/c1-3-11-20(14-17-7-5-12-22-17)16-9-10-18-15(13-16)6-4-8-19(18)21-2/h4-8,12,16H,3,9-11,13-14H2,1-2H3/t16-/m1/s1 QEYDMNFIIPJGKU-MRXNPFEDSA-N 50080049 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-thiophen-2-ylmethyl-amine::CHEMBL69706 D(2) dopamine receptor Homo sapiens 339 ChEMBL 10.1016/s0960-894x(99)00345-5 10.7270/Q2CF9P97 10465538 Hook, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308839 103980240 CHEMBL69706 ZINC26271640 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50139361 N#CC(=Cc1ccc(CN2CCN(CC2)c2ccccc2)[nH]1)C#N InChI=1S/C19H19N5/c20-13-16(14-21)12-17-6-7-18(22-17)15-23-8-10-24(11-9-23)19-4-2-1-3-5-19/h1-7,12,22H,8-11,15H2 FMWVLGRDWGHGJV-UHFFFAOYSA-N 50079642 2-[5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL293956 D(2) dopamine receptor Homo sapiens >100000 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467369 103971784 CHEMBL293956 ZINC36216462 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50139364 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 39 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50139370 N#CC(=Cc1cc(CN2CCN(CC2)c2ccccc2)c[nH]1)C#N InChI=1S/C19H19N5/c20-12-16(13-21)10-18-11-17(14-22-18)15-23-6-8-24(9-7-23)19-4-2-1-3-5-19/h1-5,10-11,14,22H,6-9,15H2 FASYQPOSAUOTDU-UHFFFAOYSA-N 50079644 2-[4-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL294459 D(2) dopamine receptor Homo sapiens 1850 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425969 103971786 CHEMBL294459 ZINC36216460 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50139379 Clc1ccc(cc1)N1CCN(Cc2c[nH]c(C=C(C#N)C#N)c2)CC1 InChI=1S/C19H18ClN5/c20-17-1-3-19(4-2-17)25-7-5-24(6-8-25)14-16-10-18(23-13-16)9-15(11-21)12-22/h1-4,9-10,13,23H,5-8,14H2 LGXAESURRIWEJV-UHFFFAOYSA-N 50079645 2-{4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile::4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-pyrrol-3-ylmethyl]-piperazin-1-ium::CHEMBL294458 D(2) dopamine receptor Homo sapiens 7350 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079645&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467371 103971787 CHEMBL294458 ZINC13862512 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50139389 N#CC(=Cc1[nH]ccc1CN1CCN(CC1)c1ccccc1)C#N InChI=1S/C19H19N5/c20-13-16(14-21)12-19-17(6-7-22-19)15-23-8-10-24(11-9-23)18-4-2-1-3-5-18/h1-7,12,22H,8-11,15H2 JXPFVJLJUKGXQP-UHFFFAOYSA-N 50079643 2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL440120 D(2) dopamine receptor Homo sapiens 4000 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467372 103971785 CHEMBL440120 ZINC36216464 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50139390 Clc1ccc(cc1)N1CCN(Cc2ccc(C=C(C#N)C#N)[nH]2)CC1 InChI=1S/C19H18ClN5/c20-16-1-5-19(6-2-16)25-9-7-24(8-10-25)14-18-4-3-17(23-18)11-15(12-21)13-22/h1-6,11,23H,7-10,14H2 HEBQIUNCEBCMFD-UHFFFAOYSA-N 50079646 2-{5-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile::4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-pyrrol-2-ylmethyl]-piperazin-1-ium::CHEMBL303538 D(2) dopamine receptor Homo sapiens 48500 ChEMBL 10.1016/s0960-894x(99)00302-9 10.7270/Q2BP020F 10450964 Haubmann, C; Hubner, H; Gmeiner, P Universität Erlangen - Nürnberg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079646&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15467370 103971788 CHEMBL303538 ZINC13862510 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142075 Nc1cccc(n1)-c1ccc(CCN2CCN(CC2)c2cccc3cccnc23)cc1 InChI=1S/C26H27N5/c27-25-8-2-6-23(29-25)21-11-9-20(10-12-21)13-15-30-16-18-31(19-17-30)24-7-1-4-22-5-3-14-28-26(22)24/h1-12,14H,13,15-19H2,(H2,27,29) BTEINZDTJWUOFJ-UHFFFAOYSA-N 50081081 6-{4-[2-(4-Quinolin-8-yl-piperazin-1-yl)-ethyl]-phenyl}-pyridin-2-ylamine::CHEMBL87187 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1016/s0960-894x(99)00432-1 10.7270/Q2BC3XRP 10498210 Lowe, JA; Qian, W; Volkmann, RA; Heck, S; Nowakowski, J; Nelson, R; Nolan, C; Liston, D; Ward, K; Zorn, S; Johnson, C; Vanase, M; Faraci, WS; Verdries, KA; Baxter, J; Doran, S; Sanders, M; Ashton, M; Whittle, P; Stefaniak, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081081&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320347 103981141 CHEMBL87187 ZINC26575573 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50142090 Nc1cccc(n1)-c1ccc(CCN2CCN(CC(=O)c3ccccc3)CC2)cc1 InChI=1S/C25H28N4O/c26-25-8-4-7-23(27-25)21-11-9-20(10-12-21)13-14-28-15-17-29(18-16-28)19-24(30)22-5-2-1-3-6-22/h1-12H,13-19H2,(H2,26,27) FUYOBXOTRAXEFA-UHFFFAOYSA-N 50081082 2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-piperazin-1-yl)-1-phenyl-ethanone::CHEMBL40391 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/s0960-894x(99)00432-1 10.7270/Q2BC3XRP 10498210 Lowe, JA; Qian, W; Volkmann, RA; Heck, S; Nowakowski, J; Nelson, R; Nolan, C; Liston, D; Ward, K; Zorn, S; Johnson, C; Vanase, M; Faraci, WS; Verdries, KA; Baxter, J; Doran, S; Sanders, M; Ashton, M; Whittle, P; Stefaniak, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081082&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9843967 103981142 CHEMBL40391 ZINC22453019 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50139974 COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3 QHLRKDSRGUZHSH-UHFFFAOYSA-N 50079939 (7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2-methoxy-phenyl)-piperidin-4-ylmethyl]-amine::CHEMBL418854 D(2) dopamine receptor Homo sapiens 13.2 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865858 103972053 CHEMBL418854 ZINC03828998 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144087 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 41 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144089 O=Cc1cccn1C1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-14-17-7-4-10-19(17)16-8-11-18(12-9-16)13-15-5-2-1-3-6-15/h1-7,10,14,16H,8-9,11-13H2 DYCKCLZHSRKOSL-UHFFFAOYSA-N 50082167 1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-2-carbaldehyde::CHEMBL109173 D(2) dopamine receptor Homo sapiens 1500 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082167&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3156990 103982014 CHEMBL109173 ZINC05736728 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144099 C(N1CCC(CC1)n1ccc(c1)-c1cnco1)c1ccccc1 InChI=1S/C19H21N3O/c1-2-4-16(5-3-1)13-21-9-7-18(8-10-21)22-11-6-17(14-22)19-12-20-15-23-19/h1-6,11-12,14-15,18H,7-10,13H2 ASGPPKHUWWRTLM-UHFFFAOYSA-N 50082170 1-Benzyl-4-(3-oxazol-5-yl-pyrrol-1-yl)-piperidine::CHEMBL107529 D(2) dopamine receptor Homo sapiens 3400 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995378 103982017 CHEMBL107529 ZINC00008565 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144105 Ic1cccn1C1CCN(Cc2ccccc2)CC1 InChI=1S/C16H19IN2/c17-16-7-4-10-19(16)15-8-11-18(12-9-15)13-14-5-2-1-3-6-14/h1-7,10,15H,8-9,11-13H2 LZMIVAWAFVXKJL-UHFFFAOYSA-N 50082171 1-Benzyl-4-(2-iodo-pyrrol-1-yl)-piperidine::CHEMBL106635 D(2) dopamine receptor Homo sapiens 8500 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508243 103982018 CHEMBL106635 ZINC20358060 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144109 C(N1CCC(CC1)n1cccc1-c1cnco1)c1ccccc1 InChI=1S/C19H21N3O/c1-2-5-16(6-3-1)14-21-11-8-17(9-12-21)22-10-4-7-18(22)19-13-20-15-23-19/h1-7,10,13,15,17H,8-9,11-12,14H2 JTHXHSNJAJMWTQ-UHFFFAOYSA-N 50082166 1-Benzyl-4-(2-oxazol-5-yl-pyrrol-1-yl)-piperidine::CHEMBL104453 D(2) dopamine receptor Homo sapiens 320 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357869 103982013 CHEMBL104453 ZINC00024249 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144135 N#CC(=Cc1cccn1C1CCN(Cc2ccccc2)CC1)C#N InChI=1S/C20H20N4/c21-14-18(15-22)13-20-7-4-10-24(20)19-8-11-23(12-9-19)16-17-5-2-1-3-6-17/h1-7,10,13,19H,8-9,11-12,16H2 WHTUEKIFAXDIRP-UHFFFAOYSA-N 50082163 2-[1-(1-Benzyl-piperidin-4-yl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL326864 D(2) dopamine receptor Homo sapiens 11000 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082163&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336552 103982010 CHEMBL326864 ZINC36216557 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144138 N#CC(=Cc1ccn(c1)C1CCN(Cc2ccccc2)CC1)C#N InChI=1S/C20H20N4/c21-13-19(14-22)12-18-6-11-24(16-18)20-7-9-23(10-8-20)15-17-4-2-1-3-5-17/h1-6,11-12,16,20H,7-10,15H2 BUGYAANIQPCORQ-UHFFFAOYSA-N 50082173 2-[1-(1-Benzyl-piperidin-4-yl)-1H-pyrrol-3-ylmethylene]-malononitrile::CHEMBL104201 D(2) dopamine receptor Homo sapiens 18000 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336571 103982020 CHEMBL104201 ZINC36216550 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50144145 C(N1CCC(CC1)n1cccc1C#Cc1ccccc1)c1ccccc1 InChI=1S/C24H24N2/c1-3-8-21(9-4-1)13-14-23-12-7-17-26(23)24-15-18-25(19-16-24)20-22-10-5-2-6-11-22/h1-12,17,24H,15-16,18-20H2 LGKGAIBCFWVOCC-UHFFFAOYSA-N 50082165 1-Benzyl-4-(2-phenylethynyl-pyrrol-1-yl)-piperidine::CHEMBL104092 D(2) dopamine receptor Homo sapiens 8300 ChEMBL 10.1016/s0960-894x(99)00540-5 10.7270/Q2W0955D 10560741 Haubmann, C; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15508238 103982012 CHEMBL104092 ZINC26836574 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149878 COc1cccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)c1 InChI=1S/C21H27ClN2O/c1-25-21-7-4-6-18(17-21)5-2-3-12-23-13-15-24(16-14-23)20-10-8-19(22)9-11-20/h4,6-11,17H,2-3,5,12-16H2,1H3 FKEVPZVICOXDLR-UHFFFAOYSA-N 50084492 1-(4-Chloro-phenyl)-4-[4-(3-methoxy-phenyl)-butyl]-piperazine(2HCL .1/2H2O)::CHEMBL318747 D(2) dopamine receptor Homo sapiens 2740 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10737150 103984037 CHEMBL318747 ZINC13804220 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149881 COc1cccc2C(=O)N(CCN3CCN(CC3)c3ccc(Cl)cc3)CCc12 InChI=1S/C22H26ClN3O2/c1-28-21-4-2-3-20-19(21)9-10-26(22(20)27)16-13-24-11-14-25(15-12-24)18-7-5-17(23)6-8-18/h2-8H,9-16H2,1H3 RSEPGIMWDIKONM-UHFFFAOYSA-N 50084487 2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-5-methoxy-3,4-dihydro-2H-isoquinolin-1-one (2HCL .3/2H2O)::CHEMBL96799 D(2) dopamine receptor Homo sapiens 3170 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084487&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810976 103984032 CHEMBL96799 ZINC13804235 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149882 COc1cccc(c1)C(=O)NCCCCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C23H30ClN3O2/c1-29-22-7-5-6-19(18-22)23(28)25-12-3-2-4-13-26-14-16-27(17-15-26)21-10-8-20(24)9-11-21/h5-11,18H,2-4,12-17H2,1H3,(H,25,28) WHRQYYUJQYMCLD-UHFFFAOYSA-N 50084484 CHEMBL94265::N-{5-[4-(4-Chloro-phenyl)-piperazin-1-yl]-pentyl}-3-methoxy-benzamide::N-{5-[4-(4-Chloro-phenyl)-piperazin-1-yl]-pentyl}-3-methoxy-benzamide (HCL) D(2) dopamine receptor Homo sapiens >850 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811814 103984029 CHEMBL94265 ZINC13492660 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149885 COc1cccc(NC(=O)CCN2CCN(CC2)c2ccc(Cl)cc2)c1 InChI=1S/C20H24ClN3O2/c1-26-19-4-2-3-17(15-19)22-20(25)9-10-23-11-13-24(14-12-23)18-7-5-16(21)6-8-18/h2-8,15H,9-14H2,1H3,(H,22,25) LDXQQYQLOMGASY-UHFFFAOYSA-N 50084483 3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-N-(3-methoxy-phenyl)-propionamide (2HCL)::CHEMBL329228 D(2) dopamine receptor Homo sapiens 282 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10761912 103984028 CHEMBL329228 ZINC13804225 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154493 O=C(NC[C@H]1CCCN1CCc1ccccc1)C1CCCCC1 InChI=1S/C20H30N2O/c23-20(18-10-5-2-6-11-18)21-16-19-12-7-14-22(19)15-13-17-8-3-1-4-9-17/h1,3-4,8-9,18-19H,2,5-7,10-16H2,(H,21,23)/t19-/m1/s1 LJIIUDVZDYITID-LJQANCHMSA-N 50086853 CHEMBL82652::Cyclohexanecarboxylic acid ((R)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460799 103985975 CHEMBL82652 ZINC26487559 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154495 O=C(NC[C@@H]1CCCN1CCc1ccccc1)C1CCCCC1 InChI=1S/C20H30N2O/c23-20(18-10-5-2-6-11-18)21-16-19-12-7-14-22(19)15-13-17-8-3-1-4-9-17/h1,3-4,8-9,18-19H,2,5-7,10-16H2,(H,21,23)/t19-/m0/s1 LJIIUDVZDYITID-IBGZPJMESA-N 50086855 CHEMBL82884::Cyclohexanecarboxylic acid ((S)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10087023 103985977 CHEMBL82884 ZINC26499988 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154496 O=C(NC[C@@H]1CCCN1CCc1ccccc1)c1ccccc1 InChI=1S/C20H24N2O/c23-20(18-10-5-2-6-11-18)21-16-19-12-7-14-22(19)15-13-17-8-3-1-4-9-17/h1-6,8-11,19H,7,12-16H2,(H,21,23)/t19-/m0/s1 PZWLNQKRFIVPJR-IBGZPJMESA-N 50086856 CHEMBL147279::N-((S)-1-Phenethyl-pyrrolidin-2-ylmethyl)-benzamide D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365114 103985978 CHEMBL147279 ZINC27561312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154498 COc1ccc(SC)cc1C(=O)NC[C@@H]1CCCN1CCc1ccccc1 InChI=1S/C22H28N2O2S/c1-26-21-11-10-19(27-2)15-20(21)22(25)23-16-18-9-6-13-24(18)14-12-17-7-4-3-5-8-17/h3-5,7-8,10-11,15,18H,6,9,12-14,16H2,1-2H3,(H,23,25)/t18-/m0/s1 WFLPEXKCKZHVKQ-SFHVURJKSA-N 50086851 2-Methoxy-5-methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-ylmethyl)-benzamide::CHEMBL356945 D(2) dopamine receptor Homo sapiens 460 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365166 103985973 CHEMBL356945 ZINC27556762 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154501 CSc1cc2CCOc2c(c1)C(=O)NC[C@H]1CCCN1CCc1ccccc1 InChI=1S/C23H28N2O2S/c1-28-20-14-18-10-13-27-22(18)21(15-20)23(26)24-16-19-8-5-11-25(19)12-9-17-6-3-2-4-7-17/h2-4,6-7,14-15,19H,5,8-13,16H2,1H3,(H,24,26)/t19-/m1/s1 NBJNMUDPZNPIDT-LJQANCHMSA-N 50086857 5-Methylsulfanyl-2,3-dihydro-benzofuran-7-carboxylic acid ((R)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL149723 D(2) dopamine receptor Homo sapiens 6.7 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365175 103985979 CHEMBL149723 ZINC27559638 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154502 O=C(NC[C@H]1CCCN1CCc1ccccc1)c1ccccc1 InChI=1S/C20H24N2O/c23-20(18-10-5-2-6-11-18)21-16-19-12-7-14-22(19)15-13-17-8-3-1-4-9-17/h1-6,8-11,19H,7,12-16H2,(H,21,23)/t19-/m1/s1 PZWLNQKRFIVPJR-LJQANCHMSA-N 50086859 CHEMBL147226::N-((R)-1-Phenethyl-pyrrolidin-2-ylmethyl)-benzamide D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365113 103985981 CHEMBL147226 ZINC27561310 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154503 CSc1cccc(c1)C(=O)NC[C@H]1CCCN1CCc1ccccc1 InChI=1S/C21H26N2OS/c1-25-20-11-5-9-18(15-20)21(24)22-16-19-10-6-13-23(19)14-12-17-7-3-2-4-8-17/h2-5,7-9,11,15,19H,6,10,12-14,16H2,1H3,(H,22,24)/t19-/m1/s1 LABFIALYPYPGFW-LJQANCHMSA-N 50086860 3-Methylsulfanyl-N-((R)-1-phenethyl-pyrrolidin-2-ylmethyl)-benzamide::CHEMBL148249 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365298 103985982 CHEMBL148249 ZINC27556839 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154504 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154510 COc1cc2CCOc2c(c1)C(=O)NC[C@@H]1CCCN1CCc1ccccc1 InChI=1S/C23H28N2O3/c1-27-20-14-18-10-13-28-22(18)21(15-20)23(26)24-16-19-8-5-11-25(19)12-9-17-6-3-2-4-7-17/h2-4,6-7,14-15,19H,5,8-13,16H2,1H3,(H,24,26)/t19-/m0/s1 UTHCVWLWDKDKNF-IBGZPJMESA-N 50086854 5-Methoxy-2,3-dihydro-benzofuran-7-carboxylic acid ((S)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL148352 D(2) dopamine receptor Homo sapiens 120 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365177 103985976 CHEMBL148352 ZINC27557014 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154517 CN1CCOc2c1cc(Cl)cc2C(=O)NC[C@@H]1CCCN1CCc1ccccc1 InChI=1S/C23H28ClN3O2/c1-26-12-13-29-22-20(14-18(24)15-21(22)26)23(28)25-16-19-8-5-10-27(19)11-9-17-6-3-2-4-7-17/h2-4,6-7,14-15,19H,5,8-13,16H2,1H3,(H,25,28)/t19-/m0/s1 ZIGNSANQGXWXBU-IBGZPJMESA-N 50086858 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL281363 D(2) dopamine receptor Homo sapiens 800 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457652 103985980 CHEMBL281363 ZINC28248590 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154519 CCCCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2N(C)CCOc12 InChI=1S/C19H28ClN3O2/c1-3-4-7-23-8-5-6-15(23)13-21-19(24)16-11-14(20)12-17-18(16)25-10-9-22(17)2/h11-12,15H,3-10,13H2,1-2H3,(H,21,24)/t15-/m0/s1 AHCLBNDBOQTPGQ-HNNXBMFYSA-N 50086852 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL283528 D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18649737 103985974 CHEMBL283528 ZINC28248328 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154522 CSc1cccc(c1)C(=O)NC[C@@H]1CCCN1CCc1ccccc1 InChI=1S/C21H26N2OS/c1-25-20-11-5-9-18(15-20)21(24)22-16-19-10-6-13-23(19)14-12-17-7-3-2-4-8-17/h2-5,7-9,11,15,19H,6,10,12-14,16H2,1H3,(H,22,24)/t19-/m0/s1 LABFIALYPYPGFW-IBGZPJMESA-N 50086861 3-Methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-ylmethyl)-benzamide::CHEMBL356304 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365299 103985983 CHEMBL356304 ZINC27556841 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154524 CCCCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2N(C)CCOc12 InChI=1S/C19H28ClN3O2/c1-3-4-7-23-8-5-6-15(23)13-21-19(24)16-11-14(20)12-17-18(16)25-10-9-22(17)2/h11-12,15H,3-10,13H2,1-2H3,(H,21,24)/t15-/m1/s1 AHCLBNDBOQTPGQ-OAHLLOKOSA-N 50086863 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL279729 D(2) dopamine receptor Homo sapiens 630 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457584 103985985 CHEMBL279729 ZINC28249164 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154526 CN1CCOc2c1cc(Cl)cc2C(=O)NC[C@H]1CCCN1CCc1ccccc1 InChI=1S/C23H28ClN3O2/c1-26-12-13-29-22-20(14-18(24)15-21(22)26)23(28)25-16-19-8-5-10-27(19)11-9-17-6-3-2-4-7-17/h2-4,6-7,14-15,19H,5,8-13,16H2,1H3,(H,25,28)/t19-/m1/s1 ZIGNSANQGXWXBU-LJQANCHMSA-N 50086862 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL279937 D(2) dopamine receptor Homo sapiens 57 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457651 103985984 CHEMBL279937 ZINC28248556 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154531 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Homo sapiens 240 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154533 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.5 ChEMBL 10.1016/s0960-894x(00)00030-5 10.7270/Q24Q7T7T 10743959 Fujio, M; Togo, Y; Tomozane, H; Kuroita, T; Morio, Y; Katayama, J; Matsumoto, Y Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154784 CN1CCc2ccc3[C@@H](N)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H18N2/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(13)19/h2-6,14,18H,7-9,19H2,1H3/t14-,18+/m1/s1 DAKGDRVNCPHAPY-KDOFPFPSSA-N 50087024 (1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::CHEMBL27251 D(2) dopamine receptor Homo sapiens 2250 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084076 103986134 CHEMBL27251 ZINC13806922 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154790 C[C@H]1c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C19H19N/c1-11-14-5-3-4-13-10-16-18-12(8-9-20(16)2)6-7-15(11)19(18)17(13)14/h3-7,11,16H,8-10H2,1-2H3/t11-,16+/m0/s1 HGMQRIBEHJQILA-MEDUHNTESA-N 50087030 (1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL27132 D(2) dopamine receptor Homo sapiens 39.2 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10706553 103986140 CHEMBL27132 ZINC13806928 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154792 CN1CCc2ccc3[C@H](O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H17NO/c1-19-8-7-10-5-6-13-17-15-11(9-14(19)16(10)17)3-2-4-12(15)18(13)20/h2-6,14,18,20H,7-9H2,1H3/t14-,18-/m1/s1 HIYLSOSERAQOHL-RDTXWAMCSA-N 50087028 (1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::CHEMBL26751 D(2) dopamine receptor Homo sapiens 23.8 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10730269 103986138 CHEMBL26751 ZINC13806907 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154794 CO[C@@]1(C)c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C20H21NO/c1-20(22-3)14-6-4-5-13-11-16-18-12(9-10-21(16)2)7-8-15(20)19(18)17(13)14/h4-8,16H,9-11H2,1-3H3/t16-,20+/m1/s1 JVZCJQBRRXZMQR-UZLBHIALSA-N 50087029 (1S,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::(6S,10aR)-6-methoxy-1,6-dimethyl-1,2,3,6,10,10a-hexahydrofluoreno[3,4,5-defg]quinoline::1-Methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL281923 D(2) dopamine receptor Homo sapiens 71 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087029&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379532 103986139 CHEMBL281923 ZINC13806934 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154802 CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31 InChI=1S/C18H19N/c1-12-5-3-7-14-11-16-18-13(9-10-19(16)2)6-4-8-15(18)17(12)14/h3-8,16H,9-11H2,1-2H3/t16-/m1/s1 IVHTVHNCRZDRRG-MRXNPFEDSA-N 50052867 (R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL27940 D(2) dopamine receptor Homo sapiens 201 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10610641 103949607 CHEMBL27940 ZINC13757612 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154804 CN1CCc2ccc3C(=O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H15NO/c1-19-8-7-10-5-6-13-17-15-11(9-14(19)16(10)17)3-2-4-12(15)18(13)20/h2-6,14H,7-9H2,1H3/t14-/m1/s1 ZVOANBRCVCBCDV-CQSZACIVSA-N 50087026 6-Methyl-5a,6,7,8-tetrahydro-5H-6-aza-benzo[mno]aceanthrylen-1-one::CHEMBL26471 D(2) dopamine receptor Homo sapiens 317 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10611439 103986136 CHEMBL26471 ZINC13806905 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154809 CCO[C@]1(CC)c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C22H25NO/c1-4-22(24-5-2)16-8-6-7-15-13-18-20-14(11-12-23(18)3)9-10-17(22)21(20)19(15)16/h6-10,18H,4-5,11-13H2,1-3H3/t18-,22-/m1/s1 IPMUUCRZGTZCPY-XMSQKQJNSA-N 50087037 1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL281554 D(2) dopamine receptor Homo sapiens 70.8 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10805599 103986147 CHEMBL281554 ZINC13806937 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154813 CO[C@]1(C)c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C20H21NO/c1-20(22-3)14-6-4-5-13-11-16-18-12(9-10-21(16)2)7-8-15(20)19(18)17(13)14/h4-8,16H,9-11H2,1-3H3/t16-,20-/m1/s1 JVZCJQBRRXZMQR-OXQOHEQNSA-N 50087033 (1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::1-Methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL281924 D(2) dopamine receptor Homo sapiens 7.1 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10062885 103986143 CHEMBL281924 ZINC13806931 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154814 CN1CCc2ccc3Cc4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H17N/c1-19-8-7-11-5-6-14-9-12-3-2-4-13-10-15(19)17(11)18(14)16(12)13/h2-6,15H,7-10H2,1H3/t15-/m1/s1 PYONGVUMQJAWOL-OAHLLOKOSA-N 50087036 6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL284586 D(2) dopamine receptor Homo sapiens 83.2 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10562462 103986146 CHEMBL284586 ZINC13806903 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154817 CCCN(CCC)[C@H]1CCc2c(F)ccc(O)c2C1 InChI=1S/C16H24FNO/c1-3-9-18(10-4-2)12-5-6-13-14(11-12)16(19)8-7-15(13)17/h7-8,12,19H,3-6,9-11H2,1-2H3/t12-/m0/s1 FNKBVTBXFLSTPB-LBPRGKRZSA-N 50013019 (S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-ol::(S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-UH-301::7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol ((S)-UH301)::CHEMBL22778::UH-301 D(2) dopamine receptor Homo sapiens 3760 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187 103925253 CHEMBL22778 61 C11698 ZINC03874895 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154818 CN1CCc2ccc3[C@H](NC(C)=O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C20H20N2O/c1-11(23)21-20-14-5-3-4-13-10-16-18-12(8-9-22(16)2)6-7-15(20)19(18)17(13)14/h3-7,16,20H,8-10H2,1-2H3,(H,21,23)/t16-,20-/m1/s1 KCDYLYMPNGUYNO-OXQOHEQNSA-N 50087032 CHEMBL282375::N-((1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-yl)-acetamide::N-(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-yl)-acetamide D(2) dopamine receptor Homo sapiens 3650 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10662302 103986142 CHEMBL282375 ZINC13806916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154819 CN1CCc2ccc3[C@@H](O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H17NO/c1-19-8-7-10-5-6-13-17-15-11(9-14(19)16(10)17)3-2-4-12(15)18(13)20/h2-6,14,18,20H,7-9H2,1H3/t14-,18+/m1/s1 HIYLSOSERAQOHL-KDOFPFPSSA-N 50087034 (1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::CHEMBL285352 D(2) dopamine receptor Homo sapiens 215 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10754042 103986144 CHEMBL285352 ZINC13806910 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154821 C[C@@H]1c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C19H19N/c1-11-14-5-3-4-13-10-16-18-12(8-9-20(16)2)6-7-15(11)19(18)17(13)14/h3-7,11,16H,8-10H2,1-2H3/t11-,16-/m1/s1 HGMQRIBEHJQILA-BDJLRTHQSA-N 50087025 (1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL282863 D(2) dopamine receptor Homo sapiens 19.4 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10825325 103986135 CHEMBL282863 ZINC13806925 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154822 CN1CCc2ccc3[C@@H](NC(C)=O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C20H20N2O/c1-11(23)21-20-14-5-3-4-13-10-16-18-12(8-9-22(16)2)6-7-15(20)19(18)17(13)14/h3-7,16,20H,8-10H2,1-2H3,(H,21,23)/t16-,20+/m1/s1 KCDYLYMPNGUYNO-UZLBHIALSA-N 50087038 CHEMBL27247::N-((1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-yl)-acetamide::N-(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-yl)-acetamide D(2) dopamine receptor Homo sapiens 7980.0 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780842 103986148 CHEMBL27247 ZINC13806918 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154830 CN1CCc2ccc3c4-c5c(cccc5C[C@@H]1c24)[C@]3(C)O InChI=1S/C19H19NO/c1-19(21)13-5-3-4-12-10-15-17-11(8-9-20(15)2)6-7-14(19)18(17)16(12)13/h3-7,15,21H,8-10H2,1-2H3/t15-,19+/m1/s1 UIYKUTOPDMMXAX-BEFAXECRSA-N 50087031 (1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::CHEMBL417473 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10707685 103986141 CHEMBL417473 ZINC13806915 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154833 CN1CCc2ccc3c4-c5c(cccc5C[C@@H]1c24)[C@@]3(C)O InChI=1S/C19H19NO/c1-19(21)13-5-3-4-12-10-15-17-11(8-9-20(15)2)6-7-14(19)18(17)16(12)13/h3-7,15,21H,8-10H2,1-2H3/t15-,19-/m1/s1 UIYKUTOPDMMXAX-DNVCBOLYSA-N 50087039 (1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::CHEMBL27309 D(2) dopamine receptor Homo sapiens 182 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10683945 103986149 CHEMBL27309 ZINC13806913 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154836 CN1CCc2cccc3-c4ccccc4C[C@@H]1c23 InChI=1S/C17H17N/c1-18-10-9-12-6-4-8-15-14-7-3-2-5-13(14)11-16(18)17(12)15/h2-8,16H,9-11H2,1H3/t16-/m1/s1 BZKUYNBAFQJRDM-MRXNPFEDSA-N 50052865 (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL281357 D(2) dopamine receptor Homo sapiens 527 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10421583 103949605 35643 CHEMBL281357 ZINC02386800 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154842 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 41.6 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154843 CCO[C@@]1(CC)c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C22H25NO/c1-4-22(24-5-2)16-8-6-7-15-13-18-20-14(11-12-23(18)3)9-10-17(22)21(20)19(15)16/h6-10,18H,4-5,11-13H2,1-3H3/t18-,22+/m1/s1 IPMUUCRZGTZCPY-GCJKJVERSA-N 50087027 1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL280804 D(2) dopamine receptor Homo sapiens 24.5 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10495891 103986137 CHEMBL280804 ZINC13806939 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154844 CN1CCc2ccc3[C@H](N)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H18N2/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(13)19/h2-6,14,18H,7-9,19H2,1H3/t14-,18-/m1/s1 DAKGDRVNCPHAPY-RDTXWAMCSA-N 50087035 (1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::CHEMBL281048 D(2) dopamine receptor Homo sapiens 261 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10706626 103986145 CHEMBL281048 ZINC13806920 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50154845 CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m1/s1 ASXGJMSKWNBENU-CQSZACIVSA-N 50016777 ((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium::(8-Hydroxyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol ((R)-OH-DPAT)::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol(8-OH-DPAT)::CHEMBL26998::R-(+)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol D(2) dopamine receptor Homo sapiens 819.0 ChEMBL 10.1021/jm9911433 10.7270/Q2RJ4HQ3 10753471 Linnanen, T; Brisander, M; Unelius, L; Sundholm, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603866 103928146 73364 CHEMBL26998 ZINC03870312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149822 COc1cccc2C(CCCN3CCN(CC3)c3ccc(Cl)cc3)CCCc12 InChI=1S/C24H31ClN2O/c1-28-24-9-3-7-22-19(5-2-8-23(22)24)6-4-14-26-15-17-27(18-16-26)21-12-10-20(25)11-13-21/h3,7,9-13,19H,2,4-6,8,14-18H2,1H3 TWAJXJHCRRIGAN-UHFFFAOYSA-N 50084485 1-(4-Chloro-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine (2HCL)::CHEMBL321557 D(2) dopamine receptor Homo sapiens 3400 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084485&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10597050 103984030 CHEMBL321557 ZINC13804244 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149827 COc1cccc(c1)C(=O)CCCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C22H27ClN2O2/c1-27-21-6-4-5-18(17-21)22(26)7-2-3-12-24-13-15-25(16-14-24)20-10-8-19(23)9-11-20/h4-6,8-11,17H,2-3,7,12-16H2,1H3 IIDSZIJSGYZPAQ-UHFFFAOYSA-N 50084481 5-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-(3-methoxy-phenyl)-pentan-1-one (HCL .3/2H2O)::CHEMBL92121 D(2) dopamine receptor Homo sapiens >850 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084481&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10715225 103984026 CHEMBL92121 ZINC13804229 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149833 COc1cccc(c1)C(=O)N(C)CCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C21H26ClN3O2/c1-23(21(26)17-4-3-5-20(16-17)27-2)10-11-24-12-14-25(15-13-24)19-8-6-18(22)7-9-19/h3-9,16H,10-15H2,1-2H3 NXCDIYDHMQLALC-UHFFFAOYSA-N 50084488 CHEMBL92411::N-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3-methoxy-N-methyl-benzamide (HCL) D(2) dopamine receptor Homo sapiens >850 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786474 103984033 CHEMBL92411 ZINC13804227 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149834 COc1cccc(c1)C(=O)NCCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C21H26ClN3O2/c1-27-20-5-2-4-17(16-20)21(26)23-10-3-11-24-12-14-25(15-13-24)19-8-6-18(22)7-9-19/h2,4-9,16H,3,10-15H2,1H3,(H,23,26) AECUHGGFVKDBMH-UHFFFAOYSA-N 50084486 CHEMBL92713::N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-3-methoxy-benzamide D(2) dopamine receptor Homo sapiens 3950 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10000302 103984031 CHEMBL92713 ZINC11909555 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149835 COc1cccc(c1)C(=O)CCCCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C23H29ClN2O2/c1-28-22-7-5-6-19(18-22)23(27)8-3-2-4-13-25-14-16-26(17-15-25)21-11-9-20(24)10-12-21/h5-7,9-12,18H,2-4,8,13-17H2,1H3 NMIDBRJGNPMELY-UHFFFAOYSA-N 50084482 6-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-(3-methoxy-phenyl)-hexan-1-one::CHEMBL96322 D(2) dopamine receptor Homo sapiens >850 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084482&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10573099 103984027 CHEMBL96322 ZINC13804232 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149841 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 876 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149842 COc1ccc2CCCC(NCCN3CCN(CC3)c3ccc(Cl)cc3)c2c1 InChI=1S/C23H30ClN3O/c1-28-21-10-5-18-3-2-4-23(22(18)17-21)25-11-12-26-13-15-27(16-14-26)20-8-6-19(24)7-9-20/h5-10,17,23,25H,2-4,11-16H2,1H3 MFLTUPXICJHQFA-UHFFFAOYSA-N 50084495 CHEMBL328283::{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine (2HCL .1/2H2O) D(2) dopamine receptor Homo sapiens 262 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10763496 103984040 CHEMBL328283 ZINC22939543 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149843 COc1ccc2CCN(CCN3CCN(CC3)c3ccc(Cl)cc3)C(=O)c2c1 InChI=1S/C22H26ClN3O2/c1-28-20-7-2-17-8-9-26(22(27)21(17)16-20)15-12-24-10-13-25(14-11-24)19-5-3-18(23)4-6-19/h2-7,16H,8-15H2,1H3 FLUICVJCLNQVDT-UHFFFAOYSA-N 50084489 2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-7-methoxy-3,4-dihydro-2H-isoquinolin-1-one::CHEMBL330470 D(2) dopamine receptor Homo sapiens 3960 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10548967 103984034 CHEMBL330470 ZINC13804238 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149847 COc1cccc(c1)C(=O)NCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C20H24ClN3O2/c1-26-19-4-2-3-16(15-19)20(25)22-9-10-23-11-13-24(14-12-23)18-7-5-17(21)6-8-18/h2-8,15H,9-14H2,1H3,(H,22,25) DQVARXSGNFBPMB-UHFFFAOYSA-N 50068366 CHEMBL93403::N-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3-methoxy-benzamide D(2) dopamine receptor Homo sapiens 1900 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3626837 103962612 CHEMBL93403 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149857 COc1cccc(CNCCN2CCN(CC2)c2ccc(Cl)cc2)c1 InChI=1S/C20H26ClN3O/c1-25-20-4-2-3-17(15-20)16-22-9-10-23-11-13-24(14-12-23)19-7-5-18(21)6-8-19/h2-8,15,22H,9-14,16H2,1H3 HANNICWFQHRKPX-UHFFFAOYSA-N 50084493 CHEMBL96462::{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-(3-methoxy-benzyl)-amine (2HCL) D(2) dopamine receptor Homo sapiens 5000 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10832341 103984038 CHEMBL96462 ZINC22939527 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149867 COc1ccc2CCCC(CCCN3CCN(CC3)c3ccc(Cl)cc3)c2c1 InChI=1S/C24H31ClN2O/c1-28-23-12-7-20-5-2-4-19(24(20)18-23)6-3-13-26-14-16-27(17-15-26)22-10-8-21(25)9-11-22/h7-12,18-19H,2-6,13-17H2,1H3 WZKDDXSAKSUASX-UHFFFAOYSA-N 50084491 1-(4-Chloro-phenyl)-4-[3-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine (2HCL)::CHEMBL420067 D(2) dopamine receptor Homo sapiens 980 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572985 103984036 CHEMBL420067 ZINC13804250 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149868 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 5.6 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149869 COc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C22H28ClN3O2/c1-28-21-6-4-5-18(17-21)22(27)24-11-2-3-12-25-13-15-26(16-14-25)20-9-7-19(23)8-10-20/h4-10,17H,2-3,11-16H2,1H3,(H,24,27) AUKXTTDRFKLJIH-UHFFFAOYSA-N 50084494 CHEMBL315879::N-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-butyl}-3-methoxy-benzamide::N-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-butyl}-3-methoxy-benzamide (HCL .5/4H2O) D(2) dopamine receptor Homo sapiens 2350 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084494&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10644771 103984039 CHEMBL315879 ZINC13492659 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50149873 COc1cccc(c1)C(=O)CCCN1CCN(CC1)c1ccc(Cl)cc1 InChI=1S/C21H25ClN2O2/c1-26-20-5-2-4-17(16-20)21(25)6-3-11-23-12-14-24(15-13-23)19-9-7-18(22)8-10-19/h2,4-5,7-10,16H,3,6,11-15H2,1H3 SQNAJQXEBGOWSC-UHFFFAOYSA-N 50084496 4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-(3-methoxy-phenyl)-butan-1-one::CHEMBL327245 D(2) dopamine receptor Homo sapiens 2550 ChEMBL 10.1021/jm991138z 10.7270/Q2610ZH4 10649982 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Universitá di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084496&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10044835 103984041 CHEMBL327245 ZINC13804218 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164563 CN1c2ccccc2CCC(N2CCN(Cc3ccc(Cl)cc3)CC2)C1=O InChI=1S/C22H26ClN3O/c1-24-20-5-3-2-4-18(20)8-11-21(22(24)27)26-14-12-25(13-15-26)16-17-6-9-19(23)10-7-17/h2-7,9-10,21H,8,11-16H2,1H3 QJZDCDLDKXELAM-UHFFFAOYSA-N 50092037 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-methyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL63209 D(2) dopamine receptor Homo sapiens 7367.0 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9908071 103990249 CHEMBL63209 ZINC26189801 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164564 CN1C(=O)C(C)(N2CCN(Cc3ccc(C)cc3)CC2)c2ccccc12 InChI=1S/C22H27N3O/c1-17-8-10-18(11-9-17)16-24-12-14-25(15-13-24)22(2)19-6-4-5-7-20(19)23(3)21(22)26/h4-11H,12-16H2,1-3H3 LUDCCCVLAYHLTE-UHFFFAOYSA-N 50092038 1,3-Dimethyl-3-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,3-dihydro-indol-2-one::CHEMBL303406 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307286 103990250 CHEMBL303406 ZINC26254150 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164569 CCN1C(=O)C(CC)(N2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 InChI=1S/C23H28ClN3O/c1-3-23(20-7-5-6-8-21(20)27(4-2)22(23)28)26-15-13-25(14-16-26)17-18-9-11-19(24)12-10-18/h5-12H,3-4,13-17H2,1-2H3 UTXCMSKCFYPXAI-UHFFFAOYSA-N 50092041 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1,3-diethyl-1,3-dihydro-indol-2-one::CHEMBL304584 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9887092 103990253 CHEMBL304584 ZINC26253357 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164573 Clc1ccc(N2CCN(C[C@H]3C[C@@H]3c3ccccc3)CC2)c(Cl)c1 InChI=1S/C20H22Cl2N2/c21-17-6-7-20(19(22)13-17)24-10-8-23(9-11-24)14-16-12-18(16)15-4-2-1-3-5-15/h1-7,13,16,18H,8-12,14H2/t16-,18-/m1/s1 AOSAPZYJOHCROI-SJLPKXTDSA-N 50092043 1-(2,4-Dichloro-phenyl)-4-((1S,2S)-2-phenyl-cyclopropylmethyl)-piperazine::CHEMBL1204116::CHEMBL302075 D(2) dopamine receptor Homo sapiens 93 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820304 103990255 CHEMBL1204116CHEMBL302075 ZINC13814442 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164576 CN1c2ccccc2CCC(N2CCN(Cc3ccc(C)cc3)CC2)C1=O InChI=1S/C23H29N3O/c1-18-7-9-19(10-8-18)17-25-13-15-26(16-14-25)22-12-11-20-5-3-4-6-21(20)24(2)23(22)27/h3-10,22H,11-17H2,1-2H3 OIUKKROQEBASAU-UHFFFAOYSA-N 50092045 1-Methyl-3-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL305061 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9950913 103990257 CHEMBL305061 ZINC26248946 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164578 Clc1ccc(CN2CCN(CC2)C2CCc3ccccc3NC2=O)cc1 InChI=1S/C21H24ClN3O/c22-18-8-5-16(6-9-18)15-24-11-13-25(14-12-24)20-10-7-17-3-1-2-4-19(17)23-21(20)26/h1-6,8-9,20H,7,10-15H2,(H,23,26) XDOUPAPTLSROOR-UHFFFAOYSA-N 50092047 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL67042 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307546 103990259 CHEMBL67042 ZINC26256162 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164583 CN1C(=O)C(Cc2ccccc12)N1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C21H24ClN3O/c1-23-19-5-3-2-4-17(19)14-20(21(23)26)25-12-10-24(11-13-25)15-16-6-8-18(22)9-7-16/h2-9,20H,10-15H2,1H3 UFFVYLYYQFBQCZ-UHFFFAOYSA-N 50092051 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-methyl-3,4-dihydro-1H-quinolin-2-one::CHEMBL305276 D(2) dopamine receptor Homo sapiens 133 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9951233 103990263 CHEMBL305276 ZINC22945187 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164588 CN(C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1)c1ccccc1 InChI=1S/C20H24ClN3O/c1-22(19-5-3-2-4-6-19)20(25)16-24-13-11-23(12-14-24)15-17-7-9-18(21)10-8-17/h2-10H,11-16H2,1H3 RLORJJLBLKRNBL-UHFFFAOYSA-N 50092040 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-N-methyl-N-phenyl-acetamide::CHEMBL303692 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092040&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307552 103990252 CHEMBL303692 ZINC26255432 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164590 Clc1ccc(CN2CCN(CC(=O)N3CCc4ccccc34)CC2)cc1 InChI=1S/C21H24ClN3O/c22-19-7-5-17(6-8-19)15-23-11-13-24(14-12-23)16-21(26)25-10-9-18-3-1-2-4-20(18)25/h1-8H,9-16H2 UHEJJZNLPMHGJA-UHFFFAOYSA-N 50092053 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-ethanone::CHEMBL69584 D(2) dopamine receptor Homo sapiens 690 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9104271 103990265 CHEMBL69584 ZINC21763183 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164594 Clc1ccc(CN2CCN(CC2)C2C(=O)Nc3ccccc23)cc1 InChI=1S/C19H20ClN3O/c20-15-7-5-14(6-8-15)13-22-9-11-23(12-10-22)18-16-3-1-2-4-17(16)21-19(18)24/h1-8,18H,9-13H2,(H,21,24) CUPNYIBJUKRTNX-UHFFFAOYSA-N 50092044 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1,3-dihydro-indol-2-one::CHEMBL305453 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307437 103990256 CHEMBL305453 ZINC26264919 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164596 Cc1ccc(CN2CCN(CC2)C2C(=O)Nc3ccccc23)cc1 InChI=1S/C20H23N3O/c1-15-6-8-16(9-7-15)14-22-10-12-23(13-11-22)19-17-4-2-3-5-18(17)21-20(19)24/h2-9,19H,10-14H2,1H3,(H,21,24) ZMGATMJPVZPSCU-UHFFFAOYSA-N 50092039 3-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1,3-dihydro-indol-2-one::CHEMBL68190 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307692 103990251 CHEMBL68190 ZINC26251022 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164597 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 113 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164600 CN1C(=O)C(C)(N2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 InChI=1S/C21H24ClN3O/c1-21(18-5-3-4-6-19(18)23(2)20(21)26)25-13-11-24(12-14-25)15-16-7-9-17(22)10-8-16/h3-10H,11-15H2,1-2H3 KRYKJSKXDBEMED-UHFFFAOYSA-N 50092048 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1,3-dimethyl-1,3-dihydro-indol-2-one::CHEMBL67429 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9799491 103990260 CHEMBL67429 ZINC26189622 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164601 CCN1C(=O)C(CC)(N2CCN(Cc3ccc(C)cc3)CC2)c2ccccc12 InChI=1S/C24H31N3O/c1-4-24(21-8-6-7-9-22(21)27(5-2)23(24)28)26-16-14-25(15-17-26)18-20-12-10-19(3)11-13-20/h6-13H,4-5,14-18H2,1-3H3 SRKXPLYPSITHJR-UHFFFAOYSA-N 50092050 1,3-Diethyl-3-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,3-dihydro-indol-2-one::CHEMBL304777 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307285 103990262 CHEMBL304777 ZINC26255537 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164607 CCN1C(=O)C(Cc2ccccc12)N1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O/c1-2-26-20-6-4-3-5-18(20)15-21(22(26)27)25-13-11-24(12-14-25)16-17-7-9-19(23)10-8-17/h3-10,21H,2,11-16H2,1H3 BZWQAKCTTBOIKJ-UHFFFAOYSA-N 50092046 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-ethyl-3,4-dihydro-1H-quinolin-2-one::CHEMBL68191 D(2) dopamine receptor Homo sapiens 21 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10045525 103990258 CHEMBL68191 ZINC22927084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164609 CCN1c2ccccc2CCC(N2CCN(Cc3ccc(Cl)cc3)CC2)C1=O InChI=1S/C23H28ClN3O/c1-2-27-21-6-4-3-5-19(21)9-12-22(23(27)28)26-15-13-25(14-16-26)17-18-7-10-20(24)11-8-18/h3-8,10-11,22H,2,9,12-17H2,1H3 MXHNYUJDGHIFRV-UHFFFAOYSA-N 50092054 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-ethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL67414 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9930722 103990266 CHEMBL67414 ZINC22927092 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164610 Clc1ccc(CN2CCN(CC2)C2Cc3ccccc3NC2=O)cc1 InChI=1S/C20H22ClN3O/c21-17-7-5-15(6-8-17)14-23-9-11-24(12-10-23)19-13-16-3-1-2-4-18(16)22-20(19)25/h1-8,19H,9-14H2,(H,22,25) NKJVFWPJNBYTCK-UHFFFAOYSA-N 50092042 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one::CHEMBL67222 D(2) dopamine receptor Homo sapiens 1373 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092042&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820048 103990254 CHEMBL67222 ZINC22945191 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164612 CCN1c2ccccc2CCC(N2CCN(Cc3ccc(C)cc3)CC2)C1=O InChI=1S/C24H31N3O/c1-3-27-22-7-5-4-6-21(22)12-13-23(24(27)28)26-16-14-25(15-17-26)18-20-10-8-19(2)9-11-20/h4-11,23H,3,12-18H2,1-2H3 IFFCYSLODLRHJM-UHFFFAOYSA-N 50092052 1-Ethyl-3-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL302340 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9929629 103990264 CHEMBL302340 ZINC26248921 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50164619 Cc1ccc(CN2CCN(CC2)C2CCc3ccccc3NC2=O)cc1 InChI=1S/C22H27N3O/c1-17-6-8-18(9-7-17)16-24-12-14-25(15-13-24)21-11-10-19-4-2-3-5-20(19)23-22(21)26/h2-9,21H,10-16H2,1H3,(H,23,26) GDOWWYCKCLQFKP-UHFFFAOYSA-N 50092049 3-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL66957 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00421-2 10.7270/Q2SN0869 10999484 Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307498 103990261 CHEMBL66957 ZINC26247428 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170505 COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3/t21-/m1/s1 HXTGXYRHXAGCFP-OAQYLSRUSA-N 50095027 (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol (M 100907)::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol(MDL 100907)::(R)-(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol::(R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(R)-(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::(R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol::CHEMBL74355::MDL 100907::MDL-100907 D(2) dopamine receptor Homo sapiens 1300 ChEMBL 10.1016/s0960-894x(00)00558-8 10.7270/Q2C24VPJ 11133070 Smith, AL; Stevenson, GI; Lewis, S; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311271 103992797 CHEMBL74355 185 ZINC00598040 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170508 C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 InChI=1S/C21H24N2/c1-3-9-17(10-4-1)21-19(13-16-23-14-7-2-8-15-23)18-11-5-6-12-20(18)22-21/h1,3-6,9-12,22H,2,7-8,13-16H2 FKIIRAHSARSGPF-UHFFFAOYSA-N 50095028 2-Phenyl-3-(2-piperidin-1-yl-ethyl)-1H-indole::CHEMBL91205 D(2) dopamine receptor Homo sapiens 900 ChEMBL 10.1016/s0960-894x(00)00558-8 10.7270/Q2C24VPJ 11133070 Smith, AL; Stevenson, GI; Lewis, S; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817960 103992798 CHEMBL91205 ZINC01489864 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170509 CN(C)CCc1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C18H20N2/c1-20(2)13-12-16-15-10-6-7-11-17(15)19-18(16)14-8-4-3-5-9-14/h3-11,19H,12-13H2,1-2H3 OCWQYTKVXQUMNM-UHFFFAOYSA-N 50095029 CHEMBL91447::Dimethyl-[2-(2-phenyl-1H-indol-3-yl)-ethyl]-amine D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095029&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903398 103992799 CHEMBL91447 ZINC00007578 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170511 C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCC1 InChI=1S/C20H22N2/c1-2-8-16(9-3-1)20-18(12-15-22-13-6-7-14-22)17-10-4-5-11-19(17)21-20/h1-5,8-11,21H,6-7,12-15H2 QGQVKTDTPMQADW-UHFFFAOYSA-N 50095031 2-Phenyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole::CHEMBL90347 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9838959 103992801 CHEMBL90347 ZINC01489863 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170512 C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCC1 InChI=1S/C19H20N2/c1-2-7-15(8-3-1)19-17(11-14-21-12-6-13-21)16-9-4-5-10-18(16)20-19/h1-5,7-10,20H,6,11-14H2 HWTZZVWBULWVDL-UHFFFAOYSA-N 50095032 3-(2-Azetidin-1-yl-ethyl)-2-phenyl-1H-indole::CHEMBL90092 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12017581 103992802 CHEMBL90092 ZINC26647056 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170513 CCN(C)CCc1c([nH]c2ccccc12)-c1cccs1 InChI=1S/C17H20N2S/c1-3-19(2)11-10-14-13-7-4-5-8-15(13)18-17(14)16-9-6-12-20-16/h4-9,12,18H,3,10-11H2,1-2H3 DMLLNVLIAHWCRT-UHFFFAOYSA-N 50095033 CHEMBL92416::Ethyl-methyl-[2-(2-thiophen-2-yl-1H-indol-3-yl)-ethyl]-amine D(2) dopamine receptor Homo sapiens 78 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324070 103992803 CHEMBL92416 ZINC26643080 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170515 CCN(C)CCc1c([nH]c2ccccc12)-c1ccc(cc1)C#N InChI=1S/C20H21N3/c1-3-23(2)13-12-18-17-6-4-5-7-19(17)22-20(18)16-10-8-15(14-21)9-11-16/h4-11,22H,3,12-13H2,1-2H3 PNXAJQBRLDGPQZ-UHFFFAOYSA-N 50095034 4-{3-[2-(Ethyl-methyl-amino)-ethyl]-1H-indol-2-yl}-benzonitrile::CHEMBL91542 D(2) dopamine receptor Homo sapiens 0.420000 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324047 103992804 CHEMBL91542 ZINC26639910 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50157605 CC(C)Oc1ccccc1N1CCN(C[C@@H](O)CNC(=O)c2ccc3C(=O)N(C(=O)c3c2)c2ccc(cc2)N(C)C)CC1 InChI=1S/C33H39N5O5/c1-22(2)43-30-8-6-5-7-29(30)37-17-15-36(16-18-37)21-26(39)20-34-31(40)23-9-14-27-28(19-23)33(42)38(32(27)41)25-12-10-24(11-13-25)35(3)4/h5-14,19,22,26,39H,15-18,20-21H2,1-4H3,(H,34,40)/t26-/m0/s1 LQTJOPPTSIYEES-SANMLTNESA-N 50088394 2-(4-Dimethylamino-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid {2-hydroxy-3-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL309106 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1021/jm9905918 10.7270/Q2XW4J20 10841797 Kuo, GH; Prouty, C; Murray, WV; Pulito, V; Jolliffe, L; Cheung, P; Varga, S; Evangelisto, M; Wang, J The R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088394&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9894665 103987309 CHEMBL309106 ZINC26273260 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50157625 CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1 DRHKJLXJIQTDTD-OAHLLOKOSA-N 50060964 (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide::5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide::5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide::CHEMBL836::TAMSULOSIN D(2) dopamine receptor Homo sapiens 78 ChEMBL 10.1021/jm9905918 10.7270/Q2XW4J20 10841797 Kuo, GH; Prouty, C; Murray, WV; Pulito, V; Jolliffe, L; Cheung, P; Varga, S; Evangelisto, M; Wang, J The R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search JGX 129211 103956570 9398 CHEMBL836 DB00706 488 C07124 ZINC01530694 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50162046 CCCNC1COc2cccc(C(N)=O)c2C1 InChI=1S/C13H18N2O2/c1-2-6-15-9-7-11-10(13(14)16)4-3-5-12(11)17-8-9/h3-5,9,15H,2,6-8H2,1H3,(H2,14,16) KARBJGIUTPWBET-UHFFFAOYSA-N 50090754 (R)-3-Propylamino-chroman-5-carboxylic acid amide::CHEMBL97773 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm990956o 10.7270/Q2610ZJK 10956192 Hammarberg, E; Nordvall, G; Leideborg, R; Nylof, M; Hanson, S; Johansson, L; Thorberg, SO; Tolf, BR; Jerning, E; Svantesson, GT; Mohell, N; Ahlgren, C; Westlind-Danielsson, A; Csoregh, I; Johansson, R AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090754&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328626 103989215 CHEMBL97773 ZINC26718657 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170522 CCN(C)CCc1c([nH]c2ccccc12)-c1cccc(F)c1 InChI=1S/C19H21FN2/c1-3-22(2)12-11-17-16-9-4-5-10-18(16)21-19(17)14-7-6-8-15(20)13-14/h4-10,13,21H,3,11-12H2,1-2H3 VCCRNQWQVWFKOO-UHFFFAOYSA-N 50095041 CHEMBL328595::Ethyl-{2-[2-(3-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amine D(2) dopamine receptor Homo sapiens 68 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324042 103992811 CHEMBL328595 ZINC26646210 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170523 CCN(C)CCc1c([nH]c2ccccc12)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C21H20F6N2/c1-3-29(2)9-8-17-16-6-4-5-7-18(16)28-19(17)13-10-14(20(22,23)24)12-15(11-13)21(25,26)27/h4-7,10-12,28H,3,8-9H2,1-2H3 BKJQLMPFZFHIMJ-UHFFFAOYSA-N 50095036 CHEMBL330303::{2-[2-(3,5-Bis-trifluoromethyl-phenyl)-1H-indol-3-yl]-ethyl}-ethyl-methyl-amine D(2) dopamine receptor Homo sapiens 187 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324051 103992806 CHEMBL330303 ZINC26647083 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170524 CCN(C)CCc1c([nH]c2ccccc12)-c1cccc(c1)[N+]([O-])=O InChI=1S/C19H21N3O2/c1-3-21(2)12-11-17-16-9-4-5-10-18(16)20-19(17)14-7-6-8-15(13-14)22(23)24/h4-10,13,20H,3,11-12H2,1-2H3 NPNPXVGDECLLAT-UHFFFAOYSA-N 50095038 CHEMBL90837::Ethyl-methyl-{2-[2-(3-nitro-phenyl)-1H-indol-3-yl]-ethyl}-amine D(2) dopamine receptor Homo sapiens 39 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324041 103992808 CHEMBL90837 ZINC26646204 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170528 C[C@@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C22H26N2/c1-17-9-7-8-15-24(17)16-14-20-19-12-5-6-13-21(19)23-22(20)18-10-3-2-4-11-18/h2-6,10-13,17,23H,7-9,14-16H2,1H3/t17-/m1/s1 PYPVMGCWFRRKNC-QGZVFWFLSA-N 50095042 3-[2-((R)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl-1H-indole::CHEMBL90263 D(2) dopamine receptor Homo sapiens 21 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095042&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324091 103992812 CHEMBL90263 ZINC03922292 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170529 COC[C@@H]1CCCN1CCc1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C22H26N2O/c1-25-16-18-10-7-14-24(18)15-13-20-19-11-5-6-12-21(19)23-22(20)17-8-3-2-4-9-17/h2-6,8-9,11-12,18,23H,7,10,13-16H2,1H3/t18-/m0/s1 YHEZQOSUVDWMEX-SFHVURJKSA-N 50095037 3-[2-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-ethyl]-2-phenyl-1H-indole::CHEMBL91446 D(2) dopamine receptor Homo sapiens 92 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324065 103992807 CHEMBL91446 ZINC26646657 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170530 CCN(C)CCc1c([nH]c2ccccc12)-c1cccc(c1)C(F)(F)F InChI=1S/C20H21F3N2/c1-3-25(2)12-11-17-16-9-4-5-10-18(16)24-19(17)14-7-6-8-15(13-14)20(21,22)23/h4-10,13,24H,3,11-12H2,1-2H3 QBUNYKZCKJJRII-UHFFFAOYSA-N 50095043 CHEMBL90911::Ethyl-methyl-{2-[2-(3-trifluoromethyl-phenyl)-1H-indol-3-yl]-ethyl}-amine D(2) dopamine receptor Homo sapiens 17 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324052 103992813 CHEMBL90911 ZINC26646126 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170532 CCN(C)CCc1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C19H22N2/c1-3-21(2)14-13-17-16-11-7-8-12-18(16)20-19(17)15-9-5-4-6-10-15/h4-12,20H,3,13-14H2,1-2H3 GRZHXPBQXHUQHO-UHFFFAOYSA-N 50095035 CHEMBL91549::Ethyl-methyl-[2-(2-phenyl-1H-indol-3-yl)-ethyl]-amine D(2) dopamine receptor Homo sapiens 85 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324017 103992805 CHEMBL91549 ZINC26647918 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170541 CCN(C)CCc1c([nH]c2ccccc12)-c1ccc(Cl)cc1 InChI=1S/C19H21ClN2/c1-3-22(2)13-12-17-16-6-4-5-7-18(16)21-19(17)14-8-10-15(20)11-9-14/h4-11,21H,3,12-13H2,1-2H3 SDFKSBYLKADGSF-UHFFFAOYSA-N 50095045 CHEMBL91463::{2-[2-(4-Chloro-phenyl)-1H-indol-3-yl]-ethyl}-ethyl-methyl-amine D(2) dopamine receptor Homo sapiens 250 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324056 103992815 CHEMBL91463 ZINC26642342 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170542 CCN(C)CCc1c([nH]c2ccccc12)-c1ccco1 InChI=1S/C17H20N2O/c1-3-19(2)11-10-14-13-7-4-5-8-15(13)18-17(14)16-9-6-12-20-16/h4-9,12,18H,3,10-11H2,1-2H3 CIXYYTIQIAPPSA-UHFFFAOYSA-N 50095046 CHEMBL92417::Ethyl-[2-(2-furan-2-yl-1H-indol-3-yl)-ethyl]-methyl-amine D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324071 103992816 CHEMBL92417 ZINC26643085 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170545 CCN(C)CCc1c([nH]c2ccccc12)-c1ccc(F)cc1 InChI=1S/C19H21FN2/c1-3-22(2)13-12-17-16-6-4-5-7-18(16)21-19(17)14-8-10-15(20)11-9-14/h4-11,21H,3,12-13H2,1-2H3 GILFIXAIAPMQCS-UHFFFAOYSA-N 50095039 CHEMBL328459::Ethyl-{2-[2-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amine D(2) dopamine receptor Homo sapiens 17 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324046 103992809 CHEMBL328459 ZINC26641114 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170551 CCN(C)CCc1c([nH]c2ccccc12)-c1ccccc1F InChI=1S/C19H21FN2/c1-3-22(2)13-12-15-14-8-5-7-11-18(14)21-19(15)16-9-4-6-10-17(16)20/h4-11,21H,3,12-13H2,1-2H3 QRWSJJRUANBJHT-UHFFFAOYSA-N 50095044 CHEMBL91197::Ethyl-{2-[2-(2-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amine D(2) dopamine receptor Homo sapiens 150 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323874 103992814 CHEMBL91197 ZINC26580256 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170552 COC[C@H]1CCCN1CCc1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C22H26N2O/c1-25-16-18-10-7-14-24(18)15-13-20-19-11-5-6-12-21(19)23-22(20)17-8-3-2-4-9-17/h2-6,8-9,11-12,18,23H,7,10,13-16H2,1H3/t18-/m1/s1 YHEZQOSUVDWMEX-GOSISDBHSA-N 50095030 3-{2-[2-((R)-Methoxymethyl)-pyrrolidin-1-yl]-ethyl}-2-phenyl-1H-indole::CHEMBL91122 D(2) dopamine receptor Homo sapiens 3000 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324084 103992800 CHEMBL91122 ZINC26647904 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170554 C[C@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C22H26N2/c1-17-9-7-8-15-24(17)16-14-20-19-12-5-6-13-21(19)23-22(20)18-10-3-2-4-11-18/h2-6,10-13,17,23H,7-9,14-16H2,1H3/t17-/m0/s1 PYPVMGCWFRRKNC-KRWDZBQOSA-N 50095047 3-[2-((S)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl-1H-indole::CHEMBL90739 D(2) dopamine receptor Homo sapiens 290 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324079 103992817 CHEMBL90739 ZINC13913276 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170558 C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 InChI=1S/C21H24N2/c1-3-9-17(10-4-1)21-19(13-16-23-14-7-2-8-15-23)18-11-5-6-12-20(18)22-21/h1,3-6,9-12,22H,2,7-8,13-16H2 FKIIRAHSARSGPF-UHFFFAOYSA-N 50095028 2-Phenyl-3-(2-piperidin-1-yl-ethyl)-1H-indole::CHEMBL91205 D(2) dopamine receptor Homo sapiens 896.0 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817960 103992798 CHEMBL91205 ZINC01489864 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50170568 CCN(CC)CCc1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C20H24N2/c1-3-22(4-2)15-14-18-17-12-8-9-13-19(17)21-20(18)16-10-6-5-7-11-16/h5-13,21H,3-4,14-15H2,1-2H3 PULCEOFVPAHMNA-UHFFFAOYSA-N 50095040 CHEMBL328257::Diethyl-[2-(2-phenyl-1H-indol-3-yl)-ethyl]-amine D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(00)00557-6 10.7270/Q27943XR 11133071 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095040&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9882537 103992810 CHEMBL328257 ZINC01489862 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50157672 CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1 DRHKJLXJIQTDTD-OAHLLOKOSA-N 50060964 (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide::5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide::5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide::CHEMBL836::TAMSULOSIN D(2) dopamine receptor Homo sapiens 13 ChEMBL 10.1021/jm9905918 10.7270/Q2XW4J20 10841797 Kuo, GH; Prouty, C; Murray, WV; Pulito, V; Jolliffe, L; Cheung, P; Varga, S; Evangelisto, M; Wang, J The R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search JGX 129211 103956570 9398 CHEMBL836 DB00706 488 C07124 ZINC01530694 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50157683 CC(C)Oc1ccccc1N1CCN(C[C@@H](O)CNC(=O)c2ccc3C(=O)N(C(=O)c3c2)c2ccc(cc2)N(C)C)CC1 InChI=1S/C33H39N5O5/c1-22(2)43-30-8-6-5-7-29(30)37-17-15-36(16-18-37)21-26(39)20-34-31(40)23-9-14-27-28(19-23)33(42)38(32(27)41)25-12-10-24(11-13-25)35(3)4/h5-14,19,22,26,39H,15-18,20-21H2,1-4H3,(H,34,40)/t26-/m0/s1 LQTJOPPTSIYEES-SANMLTNESA-N 50088394 2-(4-Dimethylamino-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid {2-hydroxy-3-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL309106 D(2) dopamine receptor Homo sapiens 23 ChEMBL 10.1021/jm9905918 10.7270/Q2XW4J20 10841797 Kuo, GH; Prouty, C; Murray, WV; Pulito, V; Jolliffe, L; Cheung, P; Varga, S; Evangelisto, M; Wang, J The R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088394&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9894665 103987309 CHEMBL309106 ZINC26273260 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50162049 CCCN(C1CCCC1)C1COc2cccc(C(N)=O)c2C1 InChI=1S/C18H26N2O2/c1-2-10-20(13-6-3-4-7-13)14-11-16-15(18(19)21)8-5-9-17(16)22-12-14/h5,8-9,13-14H,2-4,6-7,10-12H2,1H3,(H2,19,21) RPTJAEIJXWMLAQ-UHFFFAOYSA-N 50090758 (R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxylic acid amide::CHEMBL97251 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm990956o 10.7270/Q2610ZJK 10956192 Hammarberg, E; Nordvall, G; Leideborg, R; Nylof, M; Hanson, S; Johansson, L; Thorberg, SO; Tolf, BR; Jerning, E; Svantesson, GT; Mohell, N; Ahlgren, C; Westlind-Danielsson, A; Csoregh, I; Johansson, R AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090758&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328760 103989219 CHEMBL97251 ZINC26725452 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50162059 CC(C)NC1COc2cccc(C(N)=O)c2C1 InChI=1S/C13H18N2O2/c1-8(2)15-9-6-11-10(13(14)16)4-3-5-12(11)17-7-9/h3-5,8-9,15H,6-7H2,1-2H3,(H2,14,16) FVAVMEQKDWJQEM-UHFFFAOYSA-N 50090757 (R)-3-Isopropylamino-chroman-5-carboxylic acid amide::CHEMBL319403 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm990956o 10.7270/Q2610ZJK 10956192 Hammarberg, E; Nordvall, G; Leideborg, R; Nylof, M; Hanson, S; Johansson, L; Thorberg, SO; Tolf, BR; Jerning, E; Svantesson, GT; Mohell, N; Ahlgren, C; Westlind-Danielsson, A; Csoregh, I; Johansson, R AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090757&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328759 103989218 CHEMBL319403 ZINC26725029 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50162075 CCCN(C(C)C)C1COc2cccc(C(C)=O)c2C1 InChI=1S/C17H25NO2/c1-5-9-18(12(2)3)14-10-16-15(13(4)19)7-6-8-17(16)20-11-14/h6-8,12,14H,5,9-11H2,1-4H3 ZYESZLRISGYBQK-UHFFFAOYSA-N 50090771 (R)-1-[3-(Isopropyl-propyl-amino)-chroman-5-yl]-ethanone::(S)-1-[3-(Isopropyl-propyl-amino)-chroman-5-yl]-ethanone::CHEMBL97398 D(2) dopamine receptor Homo sapiens 30100 ChEMBL 10.1021/jm990956o 10.7270/Q2610ZJK 10956192 Hammarberg, E; Nordvall, G; Leideborg, R; Nylof, M; Hanson, S; Johansson, L; Thorberg, SO; Tolf, BR; Jerning, E; Svantesson, GT; Mohell, N; Ahlgren, C; Westlind-Danielsson, A; Csoregh, I; Johansson, R AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19028240 103989232 CHEMBL97398 ZINC13809365 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50162080 CCCN(CCC)C1COc2cccc(C(=O)NC(C)C)c2C1 InChI=1S/C19H30N2O2/c1-5-10-21(11-6-2)15-12-17-16(19(22)20-14(3)4)8-7-9-18(17)23-13-15/h7-9,14-15H,5-6,10-13H2,1-4H3,(H,20,22) ZHZCEXHTNIXXPU-UHFFFAOYSA-N 50090759 (R)-3-Dipropylamino-chroman-5-carboxylic acid isopropylamide::(S)-3-Dipropylamino-chroman-5-carboxylic acid isopropylamide::CHEMBL95688 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm990956o 10.7270/Q2610ZJK 10956192 Hammarberg, E; Nordvall, G; Leideborg, R; Nylof, M; Hanson, S; Johansson, L; Thorberg, SO; Tolf, BR; Jerning, E; Svantesson, GT; Mohell, N; Ahlgren, C; Westlind-Danielsson, A; Csoregh, I; Johansson, R AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328610 103989220 CHEMBL95688 ZINC13809375 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50162098 CCCN(C(C)C)C1COc2cccc(C(N)=O)c2C1 InChI=1S/C16H24N2O2/c1-4-8-18(11(2)3)12-9-14-13(16(17)19)6-5-7-15(14)20-10-12/h5-7,11-12H,4,8-10H2,1-3H3,(H2,17,19) HSIWCIOUGIRMGE-UHFFFAOYSA-N 50090764 (R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxylic acid amide::CHEMBL97268 D(2) dopamine receptor Homo sapiens >50000 ChEMBL 10.1021/jm990956o 10.7270/Q2610ZJK 10956192 Hammarberg, E; Nordvall, G; Leideborg, R; Nylof, M; Hanson, S; Johansson, L; Thorberg, SO; Tolf, BR; Jerning, E; Svantesson, GT; Mohell, N; Ahlgren, C; Westlind-Danielsson, A; Csoregh, I; Johansson, R AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19028216 103989225 CHEMBL97268 ZINC26730153 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187948 Fc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)n1 InChI=1S/C23H21FN4O2/c24-17-9-7-16(8-10-17)19-4-1-3-18(25-19)15-27-11-13-28(14-12-27)21-6-2-5-20-22(21)30-23(29)26-20/h1-10H,11-15H2,(H,26,29) XEPWZALNKJXYKD-UHFFFAOYSA-N 50103827 7-{4-[6-(4-Fluoro-phenyl)-pyridin-2-ylmethyl]-piperazin-1-yl}-3H-benzooxazol-2-one::CHEMBL419275 D(2) dopamine receptor Homo sapiens 3 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103827&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315098 103999879 CHEMBL419275 ZINC26397762 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187954 C(N1CCN(CC1)c1cccc2OCOc12)c1cccc(c1)-c1ccccc1 InChI=1S/C24H24N2O2/c1-2-7-20(8-3-1)21-9-4-6-19(16-21)17-25-12-14-26(15-13-25)22-10-5-11-23-24(22)28-18-27-23/h1-11,16H,12-15,17-18H2 SDVHBQOFRVWVQH-UHFFFAOYSA-N 50103842 1-Benzo[1,3]dioxol-4-yl-4-biphenyl-3-ylmethyl-piperazine::CHEMBL78241 D(2) dopamine receptor Homo sapiens 10 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315386 103999893 CHEMBL78241 ZINC26396117 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187955 O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4ccsc4)CC3)c2o1 InChI=1S/C22H21N3O2S/c26-22-23-19-5-2-6-20(21(19)27-22)25-10-8-24(9-11-25)14-16-3-1-4-17(13-16)18-7-12-28-15-18/h1-7,12-13,15H,8-11,14H2,(H,23,26) KTDGVFIKKDUXFL-UHFFFAOYSA-N 50103835 7-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL310045 D(2) dopamine receptor Homo sapiens 1.3 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315099 103999886 CHEMBL310045 ZINC26393131 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187956 COc1cccc(c1)-c1cccc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)c1 InChI=1S/C25H25N3O3/c1-30-21-8-3-7-20(16-21)19-6-2-5-18(15-19)17-27-11-13-28(14-12-27)23-10-4-9-22-24(23)31-25(29)26-22/h2-10,15-16H,11-14,17H2,1H3,(H,26,29) NLSPQUQPIZRWLB-UHFFFAOYSA-N 50103848 7-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL309215 D(2) dopamine receptor Homo sapiens 10 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315407 103999899 CHEMBL309215 ZINC26469475 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187957 Cc1cccc(c1)-c1cccc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)c1 InChI=1S/C25H25N3O2/c1-18-5-2-7-20(15-18)21-8-3-6-19(16-21)17-27-11-13-28(14-12-27)23-10-4-9-22-24(23)30-25(29)26-22/h2-10,15-16H,11-14,17H2,1H3,(H,26,29) GSLQHAXMHUNKAF-UHFFFAOYSA-N 50103838 7-[4-(3'-Methyl-biphenyl-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL305834 D(2) dopamine receptor Homo sapiens 9.3 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315569 103999889 CHEMBL305834 ZINC26403389 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187958 O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4cccs4)CC3)c2o1 InChI=1S/C22H21N3O2S/c26-22-23-18-6-2-7-19(21(18)27-22)25-11-9-24(10-12-25)15-16-4-1-5-17(14-16)20-8-3-13-28-20/h1-8,13-14H,9-12,15H2,(H,23,26) OGTUTKKBESFZFI-UHFFFAOYSA-N 50103831 7-[4-(3-Thiophen-2-yl-benzyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL75621 D(2) dopamine receptor Homo sapiens 2.2 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103831&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315380 103999882 CHEMBL75621 ZINC26401277 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187959 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1.4 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187961 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 69 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187963 O=C1COc2c(N1)cccc2N1CCN(Cc2cccc(c2)-c2ccccc2)CC1 InChI=1S/C25H25N3O2/c29-24-18-30-25-22(26-24)10-5-11-23(25)28-14-12-27(13-15-28)17-19-6-4-9-21(16-19)20-7-2-1-3-8-20/h1-11,16H,12-15,17-18H2,(H,26,29) FMEYZGBIOSKJJC-UHFFFAOYSA-N 50103841 8-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-4H-benzo[1,4]oxazin-3-one::CHEMBL305920 D(2) dopamine receptor Homo sapiens 1 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103841&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315382 103999892 CHEMBL305920 ZINC26400179 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187964 Fc1ccc(cc1)-c1ccnc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)c1 InChI=1S/C23H21FN4O2/c24-18-6-4-16(5-7-18)17-8-9-25-19(14-17)15-27-10-12-28(13-11-27)21-3-1-2-20-22(21)30-23(29)26-20/h1-9,14H,10-13,15H2,(H,26,29) ZSXXBLKRPFMPGJ-UHFFFAOYSA-N 50103839 7-{4-[4-(4-Fluoro-phenyl)-pyridin-2-ylmethyl]-piperazin-1-yl}-3H-benzooxazol-2-one::CHEMBL308345 D(2) dopamine receptor Homo sapiens 0.470000 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15410410 103999890 CHEMBL308345 ZINC26399124 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50173996 CN1CCc2ccc3c4c2[C@H]1Cc1cccc([nH]c3=O)c41 InChI=1S/C18H16N2O/c1-20-8-7-10-5-6-12-17-15-11(9-14(20)16(10)17)3-2-4-13(15)19-18(12)21/h2-6,14H,7-9H2,1H3,(H,19,21)/t14-/m1/s1 DTLGJDYEVFKDLJ-CQSZACIVSA-N 50202333 (R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-benzo[cd]pyren-1-one::CHEMBL253319 D(2) dopamine receptor Homo sapiens 55 ChEMBL 10.1016/s0960-894x(00)00655-7 10.7270/Q2N8792J 11212112 Linnanen, T; Brisander, M; Mohell, N; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333670 104081910 CHEMBL253319 ZINC27197072 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50175086 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OC(=O)NCc2ccccc2)c-31 InChI=1S/C27H28N2O2/c1-2-15-29-16-14-20-10-6-12-22-25(20)23(29)17-21-11-7-13-24(26(21)22)31-27(30)28-18-19-8-4-3-5-9-19/h3-13,23H,2,14-18H2,1H3,(H,28,30)/t23-/m1/s1 KLYJLIQACDTALL-HSZRJFAPSA-N 50348760 CHEMBL1806871 D(2) dopamine receptor Homo sapiens 4300 ChEMBL 10.1021/jm200347t 10.7270/Q22J6C68 21591752 Zhang, H; Ye, N; Zhou, S; Guo, L; Zheng, L; Liu, Z; Gao, B; Zhen, X; Zhang, A Soochow University College of Pharmaceutical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53362716 136355446 CHEMBL1806871 ZINC72176085 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50175092 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OC(=O)CCCCC2CCSS2)c-31 InChI=1S/C27H33NO2S2/c1-2-15-28-16-13-19-7-5-10-22-26(19)23(28)18-20-8-6-11-24(27(20)22)30-25(29)12-4-3-9-21-14-17-31-32-21/h5-8,10-11,21,23H,2-4,9,12-18H2,1H3/t21?,23-/m1/s1 JCKSBFDVTFRZJP-JFGZAKSSSA-N 50348759 CHEMBL1806874 D(2) dopamine receptor Homo sapiens 174 ChEMBL 10.1021/jm200347t 10.7270/Q22J6C68 21591752 Zhang, H; Ye, N; Zhou, S; Guo, L; Zheng, L; Liu, Z; Gao, B; Zhen, X; Zhang, A Soochow University College of Pharmaceutical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46176231 136355445 CHEMBL1806874 ZINC72177123 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50174000 CN1CCc2ccc3ncc4cccc5C[C@@H]1c2c3c45 InChI=1S/C18H16N2/c1-20-8-7-11-5-6-14-18-16-12(9-15(20)17(11)18)3-2-4-13(16)10-19-14/h2-6,10,15H,7-9H2,1H3/t15-/m1/s1 INDNLBUVGBVRHI-OAHLLOKOSA-N 50096741 (R)-7-Methyl-6a,7,8,9-tetrahydro-6H-1,7-diaza-benzo[cd]pyrene::CHEMBL122453 D(2) dopamine receptor Homo sapiens 327 ChEMBL 10.1016/s0960-894x(00)00655-7 10.7270/Q2N8792J 11212112 Linnanen, T; Brisander, M; Mohell, N; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096741&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992778 103994218 CHEMBL122453 ZINC27199038 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50174002 CN1CCc2ccc3c4c2[C@H]1Cc1cccc(oc3=O)c41 InChI=1S/C18H15NO2/c1-19-8-7-10-5-6-12-17-15(10)13(19)9-11-3-2-4-14(16(11)17)21-18(12)20/h2-6,13H,7-9H2,1H3/t13-/m1/s1 HJZYUBCMOFCAGG-CYBMUJFWSA-N 50096740 (R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-benzo[cd]pyren-1-one::CHEMBL122485 D(2) dopamine receptor Homo sapiens 541 ChEMBL 10.1016/s0960-894x(00)00655-7 10.7270/Q2N8792J 11212112 Linnanen, T; Brisander, M; Mohell, N; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096740&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44347445 103994217 CHEMBL122485 ZINC27201394 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50174004 CN1CCc2ccc3[nH]c(=O)c4cccc5C[C@@H]1c2c3c45 InChI=1S/C18H16N2O/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(21)19-13/h2-6,14H,7-9H2,1H3,(H,19,21)/t14-/m1/s1 GTFWUPYRBYXCRC-CQSZACIVSA-N 50202298 (R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benzo[cd]pyren-2-one::CHEMBL253318 D(2) dopamine receptor Homo sapiens 6110 ChEMBL 10.1016/s0960-894x(00)00655-7 10.7270/Q2N8792J 11212112 Linnanen, T; Brisander, M; Mohell, N; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202298&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448054 104081875 CHEMBL253318 ZINC27199044 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50174005 CN1CCc2ccc3oc(=O)c4cccc5C[C@@H]1c2c3c45 InChI=1S/C18H15NO2/c1-19-8-7-10-5-6-14-17-15-11(9-13(19)16(10)17)3-2-4-12(15)18(20)21-14/h2-6,13H,7-9H2,1H3/t13-/m1/s1 UCVKKWQVIIHPLH-CYBMUJFWSA-N 50096739 (R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-benzo[cd]pyren-2-one::CHEMBL124419 D(2) dopamine receptor Homo sapiens 265 ChEMBL 10.1016/s0960-894x(00)00655-7 10.7270/Q2N8792J 11212112 Linnanen, T; Brisander, M; Mohell, N; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378785 103994216 CHEMBL124419 ZINC27194163 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50174006 CN1CCc2ccc3cnc4cccc5C[C@@H]1c2c3c45 InChI=1S/C18H16N2/c1-20-8-7-11-5-6-13-10-19-14-4-2-3-12-9-15(20)17(11)18(13)16(12)14/h2-6,10,15H,7-9H2,1H3/t15-/m1/s1 XKOOJEWWQSZWFX-OAHLLOKOSA-N 50096742 (R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2,7-diaza-benzo[cd]pyrene::CHEMBL120927 D(2) dopamine receptor Homo sapiens 1330 ChEMBL 10.1016/s0960-894x(00)00655-7 10.7270/Q2N8792J 11212112 Linnanen, T; Brisander, M; Mohell, N; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10355252 103994219 CHEMBL120927 ZINC27193018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178686 C(Cc1ccccc1)N1CCC(CC1)c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C27H28N2/c1-3-9-21(10-4-1)15-18-29-19-16-22(17-20-29)26-24-13-7-8-14-25(24)28-27(26)23-11-5-2-6-12-23/h1-14,22,28H,15-20H2 MONKRYYJEIHBRU-UHFFFAOYSA-N 50095049 3-(1-Phenethyl-piperidin-4-yl)-2-phenyl-1H-indole::3-(1-phenethylpiperidin-4-yl)-2-phenyl-1H-indole::CHEMBL40584 D(2) dopamine receptor Homo sapiens 350 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10091189 103992819 CHEMBL40584 ZINC01489880 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178688 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)-c1ccc2ccccc2c1 InChI=1S/C23H20F2N2/c24-17-7-8-18-21(12-17)27-23(22(18)19-13-26-10-9-20(19)25)16-6-5-14-3-1-2-4-15(14)11-16/h1-8,11-12,19-20,26-27H,9-10,13H2/t19?,20-/m1/s1 DAUSNPVLXKKGNQ-GFOWMXPYSA-N 50099258 6-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-naphthalen-2-yl-1H-indole::CHEMBL297136 D(2) dopamine receptor Homo sapiens 500 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288594 103996174 CHEMBL297136 ZINC29392468 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178695 F[C@@H]1CCNCC1c1c([nH]c2c(F)cccc12)-c1ccccc1 InChI=1S/C19H18F2N2/c20-15-9-10-22-11-14(15)17-13-7-4-8-16(21)19(13)23-18(17)12-5-2-1-3-6-12/h1-8,14-15,22-23H,9-11H2/t14?,15-/m1/s1 KFEAQGNOINWFSL-YSSOQSIOSA-N 50099265 7-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL296867 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099265&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44289077 103996181 CHEMBL296867 ZINC29398238 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186240 CCOC(=O)c1cnn2cccc(CN3CCN(CC3)c3ccc(Cl)cc3)c12 InChI=1S/C21H23ClN4O2/c1-2-28-21(27)19-14-23-26-9-3-4-16(20(19)26)15-24-10-12-25(13-11-24)18-7-5-17(22)6-8-18/h3-9,14H,2,10-13,15H2,1H3 HZVQDNHDCAXRJP-UHFFFAOYSA-N 50102713 4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester::CHEMBL91362 D(2) dopamine receptor Homo sapiens 45000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102713&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10960333 103999149 CHEMBL91362 ZINC13863616 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186252 Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1 InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2 DTRXURJDKOYCCD-UHFFFAOYSA-N 50102712 2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyrazolo[1,5-a]pyridine::2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine::2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::4-(4-Chloro-phenyl)-1-pyrazolo[1,5-a]pyridin-2-ylmethyl-piperazin-1-ium::CHEMBL310843 D(2) dopamine receptor Homo sapiens 6300 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10336538 103999148 CHEMBL310843 974 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186257 Clc1ccc(cc1)N1CCN(Cc2cccn3nccc23)CC1 InChI=1S/C18H19ClN4/c19-16-3-5-17(6-4-16)22-12-10-21(11-13-22)14-15-2-1-9-23-18(15)7-8-20-23/h1-9H,10-14H2 LAQPIGHSUVYYGI-UHFFFAOYSA-N 50102718 4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL90374 D(2) dopamine receptor Homo sapiens 16000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102718&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10871118 103999154 CHEMBL90374 ZINC13863613 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186260 Clc1ccc(cc1)N1CCN(Cc2cccc3ccnn23)CC1 InChI=1S/C18H19ClN4/c19-15-4-6-16(7-5-15)22-12-10-21(11-13-22)14-18-3-1-2-17-8-9-20-23(17)18/h1-9H,10-14H2 UJBREZBVTYQLHJ-UHFFFAOYSA-N 50102715 7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL88937 D(2) dopamine receptor Homo sapiens 31000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102715&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11077918 103999151 CHEMBL88937 ZINC13863615 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186261 Clc1ccc(cc1)N1CCN(Cc2cccc3ccnn23)CC1 InChI=1S/C18H19ClN4/c19-15-4-6-16(7-5-15)22-12-10-21(11-13-22)14-18-3-1-2-17-8-9-20-23(17)18/h1-9H,10-14H2 UJBREZBVTYQLHJ-UHFFFAOYSA-N 50102715 7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL88937 D(2) dopamine receptor Homo sapiens 67000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102715&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11077918 103999151 CHEMBL88937 ZINC13863615 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186262 Clc1ccc(cc1)N1CCN(Cc2ccc3ccnn3c2)CC1 InChI=1S/C18H19ClN4/c19-16-2-5-17(6-3-16)22-11-9-21(10-12-22)13-15-1-4-18-7-8-20-23(18)14-15/h1-8,14H,9-13H2 VQWRIGMLIDJHJV-UHFFFAOYSA-N 50102717 6-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL432059 D(2) dopamine receptor Homo sapiens 15000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102717&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10980338 103999153 CHEMBL432059 ZINC13863614 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186263 OCc1cnn2cccc(CN3CCN(CC3)c3ccc(Cl)cc3)c12 InChI=1S/C19H21ClN4O/c20-17-3-5-18(6-4-17)23-10-8-22(9-11-23)13-15-2-1-7-24-19(15)16(14-25)12-21-24/h1-7,12,25H,8-11,13-14H2 BLLNREQHFDCHGW-UHFFFAOYSA-N 50102716 CHEMBL328925::{4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridin-3-yl}-methanol D(2) dopamine receptor Homo sapiens 39000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11078813 103999152 CHEMBL328925 ZINC13863617 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186264 Clc1ccc(cc1)N1CCN(Cc2cccn3nccc23)CC1 InChI=1S/C18H19ClN4/c19-16-3-5-17(6-4-16)22-12-10-21(11-13-22)14-15-2-1-9-23-18(15)7-8-20-23/h1-9H,10-14H2 LAQPIGHSUVYYGI-UHFFFAOYSA-N 50102718 4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL90374 D(2) dopamine receptor Homo sapiens 21000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102718&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10871118 103999154 CHEMBL90374 ZINC13863613 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186268 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 41 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186271 OCc1cnn2cccc(CN3CCN(CC3)c3ccc(Cl)cc3)c12 InChI=1S/C19H21ClN4O/c20-17-3-5-18(6-4-17)23-10-8-22(9-11-23)13-15-2-1-7-24-19(15)16(14-25)12-21-24/h1-7,12,25H,8-11,13-14H2 BLLNREQHFDCHGW-UHFFFAOYSA-N 50102716 CHEMBL328925::{4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridin-3-yl}-methanol D(2) dopamine receptor Homo sapiens 53000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11078813 103999152 CHEMBL328925 ZINC13863617 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186272 CCOC(=O)c1cnn2cccc(CN3CCN(CC3)c3ccc(Cl)cc3)c12 InChI=1S/C21H23ClN4O2/c1-2-28-21(27)19-14-23-26-9-3-4-16(20(19)26)15-24-10-12-25(13-11-24)18-7-5-17(22)6-8-18/h3-9,14H,2,10-13,15H2,1H3 HZVQDNHDCAXRJP-UHFFFAOYSA-N 50102713 4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester::CHEMBL91362 D(2) dopamine receptor Homo sapiens 37000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102713&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10960333 103999149 CHEMBL91362 ZINC13863616 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186274 Clc1ccc(cc1)N1CCN(Cc2ccc3ccnn3c2)CC1 InChI=1S/C18H19ClN4/c19-16-2-5-17(6-3-16)22-11-9-21(10-12-22)13-15-1-4-18-7-8-20-23(18)14-15/h1-8,14H,9-13H2 VQWRIGMLIDJHJV-UHFFFAOYSA-N 50102717 6-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL432059 D(2) dopamine receptor Homo sapiens 13000 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102717&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10980338 103999153 CHEMBL432059 ZINC13863614 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186275 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50186277 Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1 InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2 DTRXURJDKOYCCD-UHFFFAOYSA-N 50102712 2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyrazolo[1,5-a]pyridine::2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine::2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::4-(4-Chloro-phenyl)-1-pyrazolo[1,5-a]pyridin-2-ylmethyl-piperazin-1-ium::CHEMBL310843 D(2) dopamine receptor Homo sapiens 3400 ChEMBL 10.1021/jm015522j 10.7270/Q2542MWD 11495580 Lober, S; Hubner, H; Utz, W; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10336538 103999148 CHEMBL310843 974 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178703 C(Cc1ccccc1)N1CCCC(C1)c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C27H28N2/c1-3-10-21(11-4-1)17-19-29-18-9-14-23(20-29)26-24-15-7-8-16-25(24)28-27(26)22-12-5-2-6-13-22/h1-8,10-13,15-16,23,28H,9,14,17-20H2 HQXCPXHVSRWLFR-UHFFFAOYSA-N 50099267 3-(1-(2-Phenylethyl)piperidin-3-yl)-2-phenyl-1H-indole::3-(1-Phenethyl-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL44310 D(2) dopamine receptor Homo sapiens 500 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099267&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9821248 103996183 CHEMBL44310 ZINC13862732 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178709 F[C@@H]1CCNCC1c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C19H19FN2/c20-16-10-11-21-12-15(16)18-14-8-4-5-9-17(14)22-19(18)13-6-2-1-3-7-13/h1-9,15-16,21-22H,10-12H2/t15?,16-/m1/s1 QAMSRCBRYCCTDQ-OEMAIJDKSA-N 50099260 3-(4-Fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL41767 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288341 103996176 CHEMBL41767 ZINC29340001 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178710 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)-c1cccc2ccccc12 InChI=1S/C23H20F2N2/c24-15-8-9-18-21(12-15)27-23(22(18)19-13-26-11-10-20(19)25)17-7-3-5-14-4-1-2-6-16(14)17/h1-9,12,19-20,26-27H,10-11,13H2/t19?,20-/m1/s1 XWGNKABGVNJFEL-GFOWMXPYSA-N 50099271 6-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-naphthalen-1-yl-1H-indole::CHEMBL43060 D(2) dopamine receptor Homo sapiens 1400 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288598 103996187 CHEMBL43060 ZINC29392567 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178713 Fc1ccc(cc1)-c1[nH]c2cc(F)ccc2c1C1CCCNC1 InChI=1S/C19H18F2N2/c20-14-5-3-12(4-6-14)19-18(13-2-1-9-22-11-13)16-8-7-15(21)10-17(16)23-19/h3-8,10,13,22-23H,1-2,9,11H2 VMCOPKACEUYYIT-UHFFFAOYSA-N 50099255 6-Fluoro-2-(4-fluoro-phenyl)-3-piperidin-3-yl-1H-indole::6-Fluoro-2-(4-fluorophenyl)-3-(piperidin-3-yl)-1H-indole::CHEMBL296512 D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948670 103996171 CHEMBL296512 ZINC13862752 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178719 C1CC(CCN1)c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C19H20N2/c1-2-6-15(7-3-1)19-18(14-10-12-20-13-11-14)16-8-4-5-9-17(16)21-19/h1-9,14,20-21H,10-13H2 FWPAVENSJPMGJO-UHFFFAOYSA-N 50095050 2-Phenyl-3-piperidin-4-yl-1H-indole::2-phenyl-3-(piperidin-4-yl)-1H-indole::CHEMBL295559 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9882067 103992820 CHEMBL295559 ZINC02580888 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178726 C(N1CCCC(C1)c1c([nH]c2ccccc12)-c1ccccc1)c1ccccc1 InChI=1S/C26H26N2/c1-3-10-20(11-4-1)18-28-17-9-14-22(19-28)25-23-15-7-8-16-24(23)27-26(25)21-12-5-2-6-13-21/h1-8,10-13,15-16,22,27H,9,14,17-19H2 RXGPCIHYSMKIRI-UHFFFAOYSA-N 50099274 3-(1-Benzyl-piperidin-3-yl)-2-phenyl-1H-indole::3-(1-Benzylpiperidin-3-yl)-2-phenyl-1H-indole::CHEMBL46523 D(2) dopamine receptor Homo sapiens 1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099274&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9842124 103996190 CHEMBL46523 ZINC13862730 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178729 O[C@@H]1CCNCC1c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C19H20N2O/c22-17-10-11-20-12-15(17)18-14-8-4-5-9-16(14)21-19(18)13-6-2-1-3-7-13/h1-9,15,17,20-22H,10-12H2/t15?,17-/m1/s1 PFDVSVHNCJWHMX-OMOCHNIRSA-N 50099278 3-(2-Phenyl-1H-indol-3-yl)-piperidin-4-ol::CHEMBL288424 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288753 103996194 CHEMBL288424 ZINC29395724 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178730 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)C1CCCCC1 InChI=1S/C19H24F2N2/c20-13-6-7-14-17(10-13)23-19(12-4-2-1-3-5-12)18(14)15-11-22-9-8-16(15)21/h6-7,10,12,15-16,22-23H,1-5,8-9,11H2/t15?,16-/m1/s1 JQDBXOHJKFSLAO-OEMAIJDKSA-N 50099268 2-Cyclohexyl-6-fluoro-3-(4-fluoro-piperidin-3-yl)-1H-indole::CHEMBL40784 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099268&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288268 103996184 CHEMBL40784 ZINC29347577 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178731 CN1CCN(C)C(C1)c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C20H23N3/c1-22-12-13-23(2)18(14-22)19-16-10-6-7-11-17(16)21-20(19)15-8-4-3-5-9-15/h3-11,18,21H,12-14H2,1-2H3 SLAYQEHIFVRKNL-UHFFFAOYSA-N 50099277 3-(1,4-Dimethyl-piperazin-2-yl)-2-phenyl-1H-indole::CHEMBL40229 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10804534 103996193 CHEMBL40229 ZINC36270431 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178733 F[C@H]1CCNCC1c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C19H19FN2/c20-16-10-11-21-12-15(16)18-14-8-4-5-9-17(14)22-19(18)13-6-2-1-3-7-13/h1-9,15-16,21-22H,10-12H2/t15?,16-/m0/s1 QAMSRCBRYCCTDQ-LYKKTTPLSA-N 50099279 3-(4-Fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL41860 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288340 103996195 CHEMBL41860 ZINC29339998 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178738 CN1CCCC(C1)c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C20H22N2/c1-22-13-7-10-16(14-22)19-17-11-5-6-12-18(17)21-20(19)15-8-3-2-4-9-15/h2-6,8-9,11-12,16,21H,7,10,13-14H2,1H3 JRFXDRYERZNJFJ-UHFFFAOYSA-N 50099264 3-(1-Methyl-piperidin-3-yl)-2-phenyl-1H-indole::3-(1-Methylpiperidin-3-yl)-2-phenyl-1H-indole::CHEMBL43819 D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099264&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9838960 103996180 CHEMBL43819 ZINC13862726 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178752 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)-c1ccoc1 InChI=1S/C17H16F2N2O/c18-11-1-2-12-15(7-11)21-17(10-4-6-22-9-10)16(12)13-8-20-5-3-14(13)19/h1-2,4,6-7,9,13-14,20-21H,3,5,8H2/t13?,14-/m1/s1 YJLRKPZNGHUDFO-ARLHGKGLSA-N 50099282 6-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-furan-3-yl-1H-indole::CHEMBL289266 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288504 103996198 CHEMBL289266 ZINC29392750 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178754 F[C@@H]1CCNCC1c1c([nH]c2c(Cl)cccc12)-c1ccccc1 InChI=1S/C19H18ClFN2/c20-15-8-4-7-13-17(14-11-22-10-9-16(14)21)18(23-19(13)15)12-5-2-1-3-6-12/h1-8,14,16,22-23H,9-11H2/t14?,16-/m1/s1 BTWSXWRYWXPDBK-BZSJEYESSA-N 50099270 7-Chloro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL42784 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099270&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288638 103996186 CHEMBL42784 ZINC29390597 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178759 F[C@@H]1CCNCC1c1c([nH]c2ccc(Cl)cc12)-c1ccccc1 InChI=1S/C19H18ClFN2/c20-13-6-7-17-14(10-13)18(15-11-22-9-8-16(15)21)19(23-17)12-4-2-1-3-5-12/h1-7,10,15-16,22-23H,8-9,11H2/t15?,16-/m1/s1 PAVYFSUMGRBRPZ-OEMAIJDKSA-N 50099266 5-Chloro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL298268 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099266&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288751 103996182 CHEMBL298268 ZINC29395721 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178768 F[C@@H]1CCNCC1c1c([nH]c2ccc(F)cc12)-c1ccccc1 InChI=1S/C19H18F2N2/c20-13-6-7-17-14(10-13)18(15-11-22-9-8-16(15)21)19(23-17)12-4-2-1-3-5-12/h1-7,10,15-16,22-23H,8-9,11H2/t15?,16-/m1/s1 ITBKCDFUYADWSI-OEMAIJDKSA-N 50099254 5-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL296688 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288765 103996170 CHEMBL296688 ZINC29389159 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178773 COC(=O)c1[nH]c2cc(F)ccc2c1C1CNCC[C@H]1F InChI=1S/C15H16F2N2O2/c1-21-15(20)14-13(10-7-18-5-4-11(10)17)9-3-2-8(16)6-12(9)19-14/h2-3,6,10-11,18-19H,4-5,7H2,1H3/t10?,11-/m1/s1 CJPSOUOLAPMNQT-RRKGBCIJSA-N 50099261 6-Fluoro-3-(4-fluoro-piperidin-3-yl)-1H-indole-2-carboxylic acid methyl ester::CHEMBL288447 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099261&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288267 103996177 CHEMBL288447 ZINC29348298 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178776 C1CNCC(C1)c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C19H20N2/c1-2-7-14(8-3-1)19-18(15-9-6-12-20-13-15)16-10-4-5-11-17(16)21-19/h1-5,7-8,10-11,15,20-21H,6,9,12-13H2 FYHCOUIJWCQUMZ-UHFFFAOYSA-N 50099262 2-Phenyl-3-piperidin-3-yl-1H-indole::3-(Piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL42557 D(2) dopamine receptor Homo sapiens >1300 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099262&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9795587 103996178 CHEMBL42557 ZINC13862724 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178779 F[C@@H]1CCNCC1c1c([nH]c2cc(Cl)ccc12)-c1ccccc1 InChI=1S/C19H18ClFN2/c20-13-6-7-14-17(10-13)23-19(12-4-2-1-3-5-12)18(14)15-11-22-9-8-16(15)21/h1-7,10,15-16,22-23H,8-9,11H2/t15?,16-/m1/s1 KVZUKTSYJONTHS-OEMAIJDKSA-N 50099257 6-Chloro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL40680 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44289054 103996173 CHEMBL40680 ZINC29343353 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178788 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)-c1ccsc1 InChI=1S/C17H16F2N2S/c18-11-1-2-12-15(7-11)21-17(10-4-6-22-9-10)16(12)13-8-20-5-3-14(13)19/h1-2,4,6-7,9,13-14,20-21H,3,5,8H2/t13?,14-/m1/s1 GVERGJNQZKUDON-ARLHGKGLSA-N 50099259 6-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-thiophen-3-yl-1H-indole::CHEMBL44312 D(2) dopamine receptor Homo sapiens 1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288490 103996175 CHEMBL44312 ZINC29390769 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178793 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)-c1ccc(F)cc1 InChI=1S/C19H17F3N2/c20-12-3-1-11(2-4-12)19-18(15-10-23-8-7-16(15)22)14-6-5-13(21)9-17(14)24-19/h1-6,9,15-16,23-24H,7-8,10H2/t15?,16-/m1/s1 HXEXYULSUCMWPN-OEMAIJDKSA-N 50099269 6-Fluoro-2-(4-fluoro-phenyl)-3-(4-fluoro-piperidin-3-yl)-1H-indole::CHEMBL40312 D(2) dopamine receptor Homo sapiens 900 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099269&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288265 103996185 CHEMBL40312 ZINC29348291 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178796 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)-c1cccnc1 InChI=1S/C18H17F2N3/c19-12-3-4-13-16(8-12)23-18(11-2-1-6-21-9-11)17(13)14-10-22-7-5-15(14)20/h1-4,6,8-9,14-15,22-23H,5,7,10H2/t14?,15-/m1/s1 CHURMCWBVMVAMK-YSSOQSIOSA-N 50099276 6-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-pyridin-3-yl-1H-indole::CHEMBL41479 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288491 103996192 CHEMBL41479 ZINC29342562 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178797 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)C(=O)Nc1ccccc1 InChI=1S/C20H19F2N3O/c21-12-6-7-14-17(10-12)25-19(18(14)15-11-23-9-8-16(15)22)20(26)24-13-4-2-1-3-5-13/h1-7,10,15-16,23,25H,8-9,11H2,(H,24,26)/t15?,16-/m1/s1 WSWLUEDPQUZWSK-OEMAIJDKSA-N 50099275 6-Fluoro-3-(4-fluoro-piperidin-3-yl)-1H-indole-2-carboxylic acid phenylamide::CHEMBL41125 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099275&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288266 103996191 CHEMBL41125 ZINC29348295 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178799 O=C1NCCN1CCN1CCCC(C1)c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C24H28N4O/c29-24-25-12-14-28(24)16-15-27-13-6-9-19(17-27)22-20-10-4-5-11-21(20)26-23(22)18-7-2-1-3-8-18/h1-5,7-8,10-11,19,26H,6,9,12-17H2,(H,25,29) XTOXNGQJKCDLHX-UHFFFAOYSA-N 50099281 1-{2-[3-(2-Phenyl-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-imidazolidin-2-one::CHEMBL295596 D(2) dopamine receptor Homo sapiens >1300 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10762881 103996197 CHEMBL295596 ZINC13862734 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178806 CN1CCCCC1c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C20H22N2/c1-22-14-8-7-13-18(22)19-16-11-5-6-12-17(16)21-20(19)15-9-3-2-4-10-15/h2-6,9-12,18,21H,7-8,13-14H2,1H3 YKKPUIDGSXNPRO-UHFFFAOYSA-N 50099263 3-(1-Methyl-piperidin-2-yl)-2-phenyl-1H-indole::3-(1-Methylpiperidin-2-yl)-2-phenyl-1H-indole::CHEMBL43697 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099263&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10493741 103996179 CHEMBL43697 ZINC13862728 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178807 F[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)-c1ccccc1 InChI=1S/C19H18F2N2/c20-13-6-7-14-17(10-13)23-19(12-4-2-1-3-5-12)18(14)15-11-22-9-8-16(15)21/h1-7,10,15-16,22-23H,8-9,11H2/t15?,16-/m1/s1 NNJNAROWGAKUJQ-OEMAIJDKSA-N 50099273 6-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL288856 D(2) dopamine receptor Homo sapiens >1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10245002 103996189 CHEMBL288856 ZINC29348072 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50178810 C1COC(CN1)c1c([nH]c2ccccc12)-c1ccccc1 InChI=1S/C18H18N2O/c1-2-6-13(7-3-1)18-17(16-12-19-10-11-21-16)14-8-4-5-9-15(14)20-18/h1-9,16,19-20H,10-12H2 VCPWSWCLJDFHBL-UHFFFAOYSA-N 50099280 3-Morpholin-2-yl-2-phenyl-1H-indole::CHEMBL40284 D(2) dopamine receptor Homo sapiens 1600 ChEMBL 10.1021/jm0004998 10.7270/Q27M076K 11334570 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10588666 103996196 CHEMBL40284 ZINC12356012 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50179082 CNc1nc(Cl)c(SC)c(n1)N1CCN(C)CC1 InChI=1S/C11H18ClN5S/c1-13-11-14-9(12)8(18-3)10(15-11)17-6-4-16(2)5-7-17/h4-7H2,1-3H3,(H,13,14,15) ITYXRJDDBZMFAY-UHFFFAOYSA-N 50021365 CHEMBL407641::Mezilamine::[4-Chloro-6-(4-methyl-piperazin-1-yl)-5-methylsulfanyl-pyrimidin-2-yl]-methyl-amine D(2) dopamine receptor Homo sapiens 5.4 ChEMBL 10.1016/s0960-894x(01)00167-6 10.7270/Q2QJ7GJ8 11354362 Nishimura, T; Igarashi, J; Sunagawa, M Sumitomo Pharmaceuticals Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021365&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68678 103932069 CHEMBL407641 ZINC00001729 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50179085 CN1CCN(CC1)c1nc(C)nc(Cl)c1Sc1ccc(Cl)cc1 InChI=1S/C16H18Cl2N4S/c1-11-19-15(18)14(23-13-5-3-12(17)4-6-13)16(20-11)22-9-7-21(2)8-10-22/h3-6H,7-10H2,1-2H3 JXJXUPSKYPWNKB-UHFFFAOYSA-N 50099382 4-Chloro-5-(4-chloro-phenylsulfanyl)-2-methyl-6-(4-methyl-piperazin-1-yl)-pyrimidine::CHEMBL14998 D(2) dopamine receptor Homo sapiens 62 ChEMBL 10.1016/s0960-894x(01)00167-6 10.7270/Q2QJ7GJ8 11354362 Nishimura, T; Igarashi, J; Sunagawa, M Sumitomo Pharmaceuticals Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269825 103996298 CHEMBL14998 ZINC36216436 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50179086 CN1CCN(CC1)c1nc2ccccc2c(Cl)c1Sc1ccccc1 InChI=1S/C20H20ClN3S/c1-23-11-13-24(14-12-23)20-19(25-15-7-3-2-4-8-15)18(21)16-9-5-6-10-17(16)22-20/h2-10H,11-14H2,1H3 IKVYRMAXMYKCCI-UHFFFAOYSA-N 50099383 4-Chloro-2-(4-methyl-piperazin-1-yl)-3-phenylsulfanyl-quinoline::CHEMBL15242 D(2) dopamine receptor Homo sapiens 31 ChEMBL 10.1016/s0960-894x(01)00167-6 10.7270/Q2QJ7GJ8 11354362 Nishimura, T; Igarashi, J; Sunagawa, M Sumitomo Pharmaceuticals Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269820 103996299 CHEMBL15242 ZINC36216439 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50179089 Cc1nc(Cl)c(Sc2ccc(Cl)cc2)c(NC2CCN(Cc3ccccc3)CC2)n1 InChI=1S/C23H24Cl2N4S/c1-16-26-22(25)21(30-20-9-7-18(24)8-10-20)23(27-16)28-19-11-13-29(14-12-19)15-17-5-3-2-4-6-17/h2-10,19H,11-15H2,1H3,(H,26,27,28) AYHUGSDYEPBTFK-UHFFFAOYSA-N 50099386 (1-Benzyl-piperidin-4-yl)-[6-chloro-5-(4-chloro-phenylsulfanyl)-2-methyl-pyrimidin-4-yl]-amine::CHEMBL15270 D(2) dopamine receptor Homo sapiens 62 ChEMBL 10.1016/s0960-894x(01)00167-6 10.7270/Q2QJ7GJ8 11354362 Nishimura, T; Igarashi, J; Sunagawa, M Sumitomo Pharmaceuticals Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099386&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9847013 103996302 CHEMBL15270 ZINC36216440 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50179090 CNc1nc(Cl)c(Sc2ccccc2)c(n1)N1CCN(C)CC1 InChI=1S/C16H20ClN5S/c1-18-16-19-14(17)13(23-12-6-4-3-5-7-12)15(20-16)22-10-8-21(2)9-11-22/h3-7H,8-11H2,1-2H3,(H,18,19,20) FXWLTAOMDAMINN-UHFFFAOYSA-N 50099384 CHEMBL14899::[4-Chloro-6-(4-methyl-piperazin-1-yl)-5-phenylsulfanyl-pyrimidin-2-yl]-methyl-amine D(2) dopamine receptor Homo sapiens 188 ChEMBL 10.1016/s0960-894x(01)00167-6 10.7270/Q2QJ7GJ8 11354362 Nishimura, T; Igarashi, J; Sunagawa, M Sumitomo Pharmaceuticals Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099384&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10089203 103996300 CHEMBL14899 ZINC34190063 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50179093 O=C1[C@H]2[C@@H]3CC[C@@H](C3)[C@H]2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18- CEIJFEGBUDEYSX-FZDBZEDMSA-N 50099385 (1S,2R,6S,7R)-4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4-aza-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::CHEMBL274047 D(2) dopamine receptor Homo sapiens 460 ChEMBL 10.1016/s0960-894x(01)00167-6 10.7270/Q2QJ7GJ8 11354362 Nishimura, T; Igarashi, J; Sunagawa, M Sumitomo Pharmaceuticals Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099385&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91273 103996301 CHEMBL274047 55 ZINC01545034 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177123 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2O)c-31 InChI=1S/C24H23NO/c1-15-6-3-11-21(26)22(15)18-9-5-8-17-14-20-24-16(12-13-25(20)2)7-4-10-19(24)23(17)18/h3-11,20,26H,12-14H2,1-2H3/t20-/m1/s1 QQYBSVWWEQVBIX-HXUWFJFHSA-N 50098544 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::3-methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::CHEMBL26907 D(2) dopamine receptor Homo sapiens 3380 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593348 103995557 CHEMBL26907 ZINC13531273 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177125 COc1cccc(OC)c1-c1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C25H25NO2/c1-26-14-13-16-7-4-9-18-23-17(15-20(26)24(16)18)8-5-10-19(23)25-21(27-2)11-6-12-22(25)28-3/h4-12,20H,13-15H2,1-3H3/t20-/m1/s1 CCSCYJFJDDPPKK-HXUWFJFHSA-N 50098546 (R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL283065 D(2) dopamine receptor Homo sapiens 2030 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571274 103995559 CHEMBL283065 ZINC13531270 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177126 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2ccccc2)c-31 InChI=1S/C23H21N/c1-24-14-13-17-9-5-12-20-22-18(15-21(24)23(17)20)10-6-11-19(22)16-7-3-2-4-8-16/h2-12,21H,13-15H2,1H3/t21-/m1/s1 TVYKKVMHDGSECW-OAQYLSRUSA-N 50052869 (R)-6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL25924 D(2) dopamine receptor Homo sapiens 233 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10064053 103949609 CHEMBL25924 ZINC13757621 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177129 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(O)cccc2O)c-31 InChI=1S/C23H21NO2/c1-24-12-11-14-5-2-7-16-21-15(13-18(24)22(14)16)6-3-8-17(21)23-19(25)9-4-10-20(23)26/h2-10,18,25-26H,11-13H2,1H3/t18-/m1/s1 WJRKPLARAFQQGZ-GOSISDBHSA-N 50098545 (R)-2-(6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzene-1,3-diol::CHEMBL281273 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10807321 103995558 CHEMBL281273 ZINC13862602 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177133 CN1CCc2ccc3[C@@H](N)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H18N2/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(13)19/h2-6,14,18H,7-9,19H2,1H3/t14-,18+/m1/s1 DAKGDRVNCPHAPY-KDOFPFPSSA-N 50087024 (1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::CHEMBL27251 D(2) dopamine receptor Homo sapiens 2250 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084076 103986134 CHEMBL27251 ZINC13806922 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177138 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2C#N)c-31 InChI=1S/C25H22N2/c1-16-6-3-9-19(15-26)23(16)20-10-5-8-18-14-22-25-17(12-13-27(22)2)7-4-11-21(25)24(18)20/h3-11,22H,12-14H2,1-2H3/t22-/m1/s1 APEZAWGOFKUHCA-JOCHJYFZSA-N 50098549 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::3-Methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::CHEMBL28056 D(2) dopamine receptor Homo sapiens 2470 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11725453 103995562 CHEMBL28056 ZINC01493886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177144 CN1CCc2cccc3-c4ccccc4C[C@@H]1c23 InChI=1S/C17H17N/c1-18-10-9-12-6-4-8-15-14-7-3-2-5-13(14)11-16(18)17(12)15/h2-8,16H,9-11H2,1H3/t16-/m1/s1 BZKUYNBAFQJRDM-MRXNPFEDSA-N 50052865 (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL281357 D(2) dopamine receptor Homo sapiens 527 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10421583 103949605 35643 CHEMBL281357 ZINC02386800 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187912 O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4cccc(c4)C#N)CC3)c2o1 InChI=1S/C25H22N4O2/c26-16-18-4-1-6-20(14-18)21-7-2-5-19(15-21)17-28-10-12-29(13-11-28)23-9-3-8-22-24(23)31-25(30)27-22/h1-9,14-15H,10-13,17H2,(H,27,30) QVMGHXPGUROPFY-UHFFFAOYSA-N 50103828 3'-[4-(2-Oxo-2,3-dihydro-benzooxazol-7-yl)-piperazin-1-ylmethyl]-biphenyl-3-carbonitrile::CHEMBL80156 D(2) dopamine receptor Homo sapiens 6 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103828&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315453 103999880 CHEMBL80156 ZINC26470065 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187913 Fc1ccc(cc1)-c1ccc(CN2CCN(CC2)c2cccc3ccoc23)[nH]1 InChI=1S/C23H22FN3O/c24-19-6-4-17(5-7-19)21-9-8-20(25-21)16-26-11-13-27(14-12-26)22-3-1-2-18-10-15-28-23(18)22/h1-10,15,25H,11-14,16H2 PGNHBJGIQAEIHD-UHFFFAOYSA-N 50020174 1-Benzofuran-7-yl-4-[5-(4-fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperazine::CHEMBL292187::Elopiprazole D(2) dopamine receptor Homo sapiens 0.420000 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 208917 103931091 CHEMBL292187 ZINC53098495 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187914 O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4ccccc4)CC3)c2o1 InChI=1S/C24H23N3O2/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19/h1-11,16H,12-15,17H2,(H,25,28) CYGODHVAJQTCBG-UHFFFAOYSA-N 50241119 7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzooxazol-2-one::BIFEPRUNOX::CHEMBL218166 D(2) dopamine receptor Homo sapiens 2.2 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 208951 104098615 CHEMBL218166 DB04888 ZINC52971454 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187916 COc1ccccc1N1CCN(CCNC(=O)c2ccc(F)cc2)CC1 InChI=1S/C20H24FN3O2/c1-26-19-5-3-2-4-18(19)24-14-12-23(13-15-24)11-10-22-20(25)16-6-8-17(21)9-7-16/h2-9H,10-15H2,1H3,(H,22,25) GTATVXRFYOQYFS-UHFFFAOYSA-N 50019960 4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL58377 D(2) dopamine receptor Homo sapiens 5 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13318472 103930883 CHEMBL58377 ZINC52969696 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187917 C(N1CCN(CC1)c1cccc2NCCOc12)c1cccc(c1)-c1ccccc1 InChI=1S/C25H27N3O/c1-2-7-21(8-3-1)22-9-4-6-20(18-22)19-27-13-15-28(16-14-27)24-11-5-10-23-25(24)29-17-12-26-23/h1-11,18,26H,12-17,19H2 FNEYDYBEZUNJRD-UHFFFAOYSA-N 50103830 8-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3,4-dihydro-2H-benzo[1,4]oxazine::CHEMBL310048 D(2) dopamine receptor Homo sapiens 0.930000 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103830&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315381 103999881 CHEMBL310048 ZINC26401281 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187919 C(N1CCN(CC1)c1cccc2ccoc12)c1cccc(c1)-c1ccccc1 InChI=1S/C25H24N2O/c1-2-7-21(8-3-1)23-10-4-6-20(18-23)19-26-13-15-27(16-14-26)24-11-5-9-22-12-17-28-25(22)24/h1-12,17-18H,13-16,19H2 KVZSNZYKLPCLCR-UHFFFAOYSA-N 50103832 1-Benzofuran-7-yl-4-biphenyl-3-ylmethyl-piperazine::CHEMBL308875 D(2) dopamine receptor Homo sapiens 8.1 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103832&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315568 103999883 CHEMBL308875 ZINC26401658 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187920 Fc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)c1 InChI=1S/C24H22FN3O2/c25-20-9-7-18(8-10-20)19-4-1-3-17(15-19)16-27-11-13-28(14-12-27)22-6-2-5-21-23(22)30-24(29)26-21/h1-10,15H,11-14,16H2,(H,26,29) PVVDKVCBIPGTQT-UHFFFAOYSA-N 50103833 7-[4-(4'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL306830 D(2) dopamine receptor Homo sapiens 8.1 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315427 103999884 CHEMBL306830 ZINC26395342 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187923 Oc1ccc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)cc1-c1ccccc1 InChI=1S/C24H23N3O3/c28-22-10-9-17(15-19(22)18-5-2-1-3-6-18)16-26-11-13-27(14-12-26)21-8-4-7-20-23(21)30-24(29)25-20/h1-10,15,28H,11-14,16H2,(H,25,29) AIPVMDNBQLPSHM-UHFFFAOYSA-N 50103826 7-[4-(6-Hydroxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL80230 D(2) dopamine receptor Homo sapiens 0.410000 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315406 103999878 CHEMBL80230 ZINC26469466 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187925 Fc1ccc(cc1CN1CCN(CC1)c1cccc2[nH]c(=O)oc12)-c1ccccc1 InChI=1S/C24H22FN3O2/c25-20-10-9-18(17-5-2-1-3-6-17)15-19(20)16-27-11-13-28(14-12-27)22-8-4-7-21-23(22)30-24(29)26-21/h1-10,15H,11-14,16H2,(H,26,29) YTLARIHDMMQLCL-UHFFFAOYSA-N 50103837 7-[4-(4-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL77334 D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103837&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315131 103999888 CHEMBL77334 ZINC26398493 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187931 C(N1CCN(CC1)c1cccc2OCCOc12)c1cccc(c1)-c1ccccc1 InChI=1S/C25H26N2O2/c1-2-7-21(8-3-1)22-9-4-6-20(18-22)19-26-12-14-27(15-13-26)23-10-5-11-24-25(23)29-17-16-28-24/h1-11,18H,12-17,19H2 XVRGSHVTZMJIAN-UHFFFAOYSA-N 50103840 1-Biphenyl-3-ylmethyl-4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine::CHEMBL77472 D(2) dopamine receptor Homo sapiens 1.7 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103840&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9932051 103999891 CHEMBL77472 ZINC53151202 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187932 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Homo sapiens 3.1 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187934 O=c1[nH]c2cccc(N3CCN(Cc4cncc(c4)-c4ccccc4)CC3)c2o1 InChI=1S/C23H22N4O2/c28-23-25-20-7-4-8-21(22(20)29-23)27-11-9-26(10-12-27)16-17-13-19(15-24-14-17)18-5-2-1-3-6-18/h1-8,13-15H,9-12,16H2,(H,25,28) ZPYBYTJAEKTXBQ-UHFFFAOYSA-N 50103843 7-[4-(5-Phenyl-pyridin-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL76990 D(2) dopamine receptor Homo sapiens 1.8 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10340117 103999894 CHEMBL76990 ZINC26398147 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187938 Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2[nH]c(=O)oc12 InChI=1S/C20H21FN4O3/c21-15-6-4-14(5-7-15)19(26)22-8-9-24-10-12-25(13-11-24)17-3-1-2-16-18(17)28-20(27)23-16/h1-7H,8-13H2,(H,22,26)(H,23,27) XURLIKHUHWMOTE-UHFFFAOYSA-N 50103834 4-Fluoro-N-{2-[4-(2-oxo-2,3-dihydro-benzooxazol-7-yl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL78058 D(2) dopamine receptor Homo sapiens 4.6 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103834&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315548 103999885 CHEMBL78058 ZINC26395653 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187941 C(N1CCN(CC1)c1cccc2NCCCc12)c1cccc(c1)-c1ccccc1 InChI=1S/C26H29N3/c1-2-8-22(9-3-1)23-10-4-7-21(19-23)20-28-15-17-29(18-16-28)26-13-5-12-25-24(26)11-6-14-27-25/h1-5,7-10,12-13,19,27H,6,11,14-18,20H2 FJDXZJPLGPQEMF-UHFFFAOYSA-N 50103844 5-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-1,2,3,4-tetrahydro-quinoline::CHEMBL308476 D(2) dopamine receptor Homo sapiens 4 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315383 103999895 CHEMBL308476 ZINC26400183 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187942 Cn1c2cccc(N3CCN(Cc4cccc(c4)-c4ccccc4)CC3)c2oc1=O InChI=1S/C25H25N3O2/c1-26-22-11-6-12-23(24(22)30-25(26)29)28-15-13-27(14-16-28)18-19-7-5-10-21(17-19)20-8-3-2-4-9-20/h2-12,17H,13-16,18H2,1H3 CUMDYMGWFWPPEV-UHFFFAOYSA-N 50103836 7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3-methyl-3H-benzooxazol-2-one::CHEMBL306634 D(2) dopamine receptor Homo sapiens 10 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315120 103999887 CHEMBL306634 ZINC26398648 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187943 Clc1cccc(c1)-c1cccc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)c1 InChI=1S/C24H22ClN3O2/c25-20-7-2-6-19(15-20)18-5-1-4-17(14-18)16-27-10-12-28(13-11-27)22-9-3-8-21-23(22)30-24(29)26-21/h1-9,14-15H,10-13,16H2,(H,26,29) UCRCPOHUGHGPRU-UHFFFAOYSA-N 50103845 7-[4-(3'-Chloro-biphenyl-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL77934 D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315426 103999896 CHEMBL77934 ZINC26395338 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187944 O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4ccccc4C#N)CC3)c2o1 InChI=1S/C25H22N4O2/c26-16-20-6-1-2-8-21(20)19-7-3-5-18(15-19)17-28-11-13-29(14-12-28)23-10-4-9-22-24(23)31-25(30)27-22/h1-10,15H,11-14,17H2,(H,27,30) LDAVXMLOCRPMGX-UHFFFAOYSA-N 50103847 3'-[4-(2-Oxo-2,3-dihydro-benzooxazol-7-yl)-piperazin-1-ylmethyl]-biphenyl-2-carbonitrile::CHEMBL420016 D(2) dopamine receptor Homo sapiens 2 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44315436 103999898 CHEMBL420016 ZINC26395657 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50187945 Fc1ccc(cc1)-c1cc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)ccn1 InChI=1S/C23H21FN4O2/c24-18-6-4-17(5-7-18)20-14-16(8-9-25-20)15-27-10-12-28(13-11-27)21-3-1-2-19-22(21)30-23(29)26-19/h1-9,14H,10-13,15H2,(H,26,29) OPIFKCUXRNZZDK-UHFFFAOYSA-N 50103846 7-{4-[2-(4-Fluoro-phenyl)-pyridin-4-ylmethyl]-piperazin-1-yl}-3H-benzooxazol-2-one::CHEMBL74805 D(2) dopamine receptor Homo sapiens 2.9 ChEMBL 10.1016/s0960-894x(01)00425-5 10.7270/Q2RR1XH9 11527728 Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15410404 103999897 CHEMBL74805 ZINC52594809 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177146 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Homo sapiens 41.9 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177147 O=C1Nc2cccc3CCC[C@@]1(CCCCN1CCC(=CC1)c1ccccc1)c23 InChI=1S/C26H30N2O/c29-25-26(16-7-11-22-10-6-12-23(27-25)24(22)26)15-4-5-17-28-18-13-21(14-19-28)20-8-2-1-3-9-20/h1-3,6,8-10,12-13H,4-5,7,11,14-19H2,(H,27,29)/t26-/m0/s1 JBQOYPLKTTXLSQ-SANMLTNESA-N 50098548 (R)-2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-2a,3,4,5-tetrahydrobenzo[cd]indol-2(1H)-one::2a-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-2a,3,4,5-tetrahydro-1H-benzo[cd]indol-2-one::CHEMBL25815 D(2) dopamine receptor Homo sapiens 105 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276598 103995561 CHEMBL25815 ZINC01902852 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177149 CN1CCc2cccc-3c2[C@H]1Cc1cccc(c-31)-c1c(OS(=O)(=O)C(F)(F)F)cccc1OS(=O)(=O)C(F)(F)F InChI=1S/C25H19F6NO6S2/c1-32-12-11-14-5-2-7-16-21-15(13-18(32)22(14)16)6-3-8-17(21)23-19(37-39(33,34)24(26,27)28)9-4-10-20(23)38-40(35,36)25(29,30)31/h2-10,18H,11-13H2,1H3/t18-/m1/s1 PNFSZBQKXYOEES-GOSISDBHSA-N 50098547 (R)-Trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester::CHEMBL282413 D(2) dopamine receptor Homo sapiens 2260 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10698929 103995560 CHEMBL282413 ZINC36248252 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177152 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2O)c-31 InChI=1S/C24H23NO/c1-15-6-3-11-21(26)22(15)18-9-5-8-17-14-20-24-16(12-13-25(20)2)7-4-10-19(24)23(17)18/h3-11,20,26H,12-14H2,1-2H3/t20-/m1/s1 QQYBSVWWEQVBIX-HXUWFJFHSA-N 50098544 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::3-methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::CHEMBL26907 D(2) dopamine receptor Homo sapiens 3380 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593348 103995557 CHEMBL26907 ZINC13531273 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177153 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2C#N)c-31 InChI=1S/C25H22N2/c1-16-6-3-9-19(15-26)23(16)20-10-5-8-18-14-22-25-17(12-13-27(22)2)7-4-11-21(25)24(18)20/h3-11,22H,12-14H2,1-2H3/t22-/m1/s1 APEZAWGOFKUHCA-JOCHJYFZSA-N 50098549 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::3-Methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::CHEMBL28056 D(2) dopamine receptor Homo sapiens 2470 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11725453 103995562 CHEMBL28056 ZINC01493886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177156 C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1cccc(C)c1 InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1 AGVNHDNTFYHZNL-QGZVFWFLSA-N 50098550 3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide::3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide::3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide (SB-258719)::4-Methyl-1-[(R)-3-methyl-4-(toluene-3-sulfonyl)-pentyl]-piperidine::CHEMBL12264::SB-258719 D(2) dopamine receptor Homo sapiens 3981 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5312148 103995563 CHEMBL12264 281 ZINC00007275 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50177163 CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1 HWKROQUZSKPIKQ-MRXNPFEDSA-N 50098551 (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol::(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol::3-{(R)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol::3-{(S)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol::3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol::3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol (SB-269970)::CHEMBL282199::SB-269970 D(2) dopamine receptor Homo sapiens 316 ChEMBL 10.1021/jm0108505 10.7270/Q23X85WM 11311055 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604889 103995564 CHEMBL282199 3233 ZINC03982174 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50192610 CCOC(=O)c1[nH]c2ccccc2c1CCN(C)C InChI=1S/C15H20N2O2/c1-4-19-15(18)14-12(9-10-17(2)3)11-7-5-6-8-13(11)16-14/h5-8,16H,4,9-10H2,1-3H3 DHMRDBMKJIHQOM-UHFFFAOYSA-N 50106247 3-(2-Dimethylamino-ethyl)-1H-indole-2-carboxylic acid ethyl ester::CHEMBL317535 D(2) dopamine receptor Homo sapiens 59 ChEMBL 10.1021/jm010943m 10.7270/Q2T72GRW 11689074 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11747350 104001820 CHEMBL317535 ZINC13864767 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50192625 CN(C)CCc1cn(C(=O)c2ccccc2)c2ccc(O)cc12 InChI=1S/C19H20N2O2/c1-20(2)11-10-15-13-21(18-9-8-16(22)12-17(15)18)19(23)14-6-4-3-5-7-14/h3-9,12-13,22H,10-11H2,1-2H3 UJELDYRUBKQNKE-UHFFFAOYSA-N 50106252 CHEMBL263700::[3-(2-Dimethylamino-ethyl)-5-hydroxy-indol-1-yl]-phenyl-methanone D(2) dopamine receptor Homo sapiens >2200 ChEMBL 10.1021/jm010943m 10.7270/Q2T72GRW 11689074 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796627 104001825 CHEMBL263700 ZINC13864761 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50192632 NCCc1cccc2n(ccc12)S(=O)(=O)c1ccccc1 InChI=1S/C16H16N2O2S/c17-11-9-13-5-4-8-16-15(13)10-12-18(16)21(19,20)14-6-2-1-3-7-14/h1-8,10,12H,9,11,17H2 VNWSJGQXBGKBED-UHFFFAOYSA-N 50106251 2-(1-Benzenesulfonyl-1H-indol-4-yl)-ethylamine::CHEMBL125745 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm010943m 10.7270/Q2T72GRW 11689074 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817810 104001824 CHEMBL125745 ZINC00008954 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50192636 COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1 InChI=1S/C19H22N2O3S/c1-20(2)12-11-15-14-21(19-10-9-16(24-3)13-18(15)19)25(22,23)17-7-5-4-6-8-17/h4-10,13-14H,11-12H2,1-3H3 AIJIQCBYMBZLJD-UHFFFAOYSA-N 34141 CHEMBL76237::MS-245 D(2) dopamine receptor Homo sapiens 210 ChEMBL 10.1021/jm010943m 10.7270/Q2T72GRW 11689074 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34141&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6918542 85301149 CHEMBL76237 ZINC13553349 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50192643 CN(C)CCc1cccc2n(c(cc12)C(=O)c1ccccc1)S(=O)(=O)c1ccccc1 InChI=1S/C25H24N2O3S/c1-26(2)17-16-19-12-9-15-23-22(19)18-24(25(28)20-10-5-3-6-11-20)27(23)31(29,30)21-13-7-4-8-14-21/h3-15,18H,16-17H2,1-2H3 PBBGIYKMAVNTAL-UHFFFAOYSA-N 50106246 CHEMBL126340::[1-Benzenesulfonyl-4-(2-dimethylamino-ethyl)-1H-indol-2-yl]-phenyl-methanone D(2) dopamine receptor Homo sapiens 750 ChEMBL 10.1021/jm010943m 10.7270/Q2T72GRW 11689074 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9867475 104001819 CHEMBL126340 ZINC00590474 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50192644 CN(C)CCc1cccc2n(ccc12)S(=O)(=O)c1ccccc1 InChI=1S/C18H20N2O2S/c1-19(2)13-11-15-7-6-10-18-17(15)12-14-20(18)23(21,22)16-8-4-3-5-9-16/h3-10,12,14H,11,13H2,1-2H3 GIHFRARKMBMXPG-UHFFFAOYSA-N 50106249 CHEMBL92139::[2-(1-Benzenesulfonyl-1H-indol-4-yl)-ethyl]-dimethyl-amine D(2) dopamine receptor Homo sapiens 1600 ChEMBL 10.1021/jm010943m 10.7270/Q2T72GRW 11689074 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9862256 104001822 CHEMBL92139 ZINC00026677 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50192649 CN(C)[C@H]1Cc2cn(c3cccc([C@@H]1O)c23)S(=O)(=O)c1ccc(C)cc1 InChI=1S/C20H22N2O3S/c1-13-7-9-15(10-8-13)26(24,25)22-12-14-11-18(21(2)3)20(23)16-5-4-6-17(22)19(14)16/h4-10,12,18,20,23H,11H2,1-3H3/t18-,20-/m0/s1 OVDROBGSEQOKQB-ICSRJNTNSA-N 50106248 (4S,5S)-4-Dimethylamino-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-5-ol::4-Dimethylamino-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-5-ol::CHEMBL127411 D(2) dopamine receptor Homo sapiens >1700 ChEMBL 10.1021/jm010943m 10.7270/Q2T72GRW 11689074 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6918601 104001821 CHEMBL127411 ZINC13864770 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50208121 [O-][N+](=O)c1ccccc1S(=O)(=O)NC[C@H]1CC[C@H](CNCC2CCc3ccccc3C2)CC1 InChI=1S/C25H33N3O4S/c29-28(30)24-7-3-4-8-25(24)33(31,32)27-18-20-11-9-19(10-12-20)16-26-17-21-13-14-22-5-1-2-6-23(22)15-21/h1-8,19-21,26-27H,9-18H2/t19-,20-,21? ISSSVYKMIIAPTH-YGQOYYDZSA-N 50114974 2-Nitro-N-(4-{[(1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-amino]-methyl}-cyclohexylmethyl)-benzenesulfonamide::2-nitro-N-((4-(((1,2,3,4-tetrahydronaphthalen-2-yl)methylamino)methyl)cyclohexyl)methyl)benzenesulfonamide::CHEMBL299879 D(2) dopamine receptor Homo sapiens 63 ChEMBL 10.1016/s0960-894x(02)00287-1 10.7270/Q2JD4W4S 12067557 Islam, I; Dhanoa, D; Finn, J; Du, P; Walker, MW; Salon, JA; Zhang, J; Gluchowski, C Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114974&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9982218 104008962 CHEMBL299879 ZINC08022499 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50192705 CN(C)CCc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 InChI=1S/C18H20N2O2S/c1-19(2)13-12-15-14-20(18-11-7-6-10-17(15)18)23(21,22)16-8-4-3-5-9-16/h3-11,14H,12-13H2,1-2H3 NKLZWGMWROXIDH-UHFFFAOYSA-N 50106250 CHEMBL93868::N,N-dimethyl-2-(1-(phenylsulfonyl)-1H-indol-3-yl)ethanamine::[2-(1-Benzenesulfonyl-1H-indol-3-yl)-ethyl]-dimethyl-amine D(2) dopamine receptor Homo sapiens 62 ChEMBL 10.1021/jm010943m 10.7270/Q2T72GRW 11689074 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9927441 104001823 CHEMBL93868 ZINC13553351 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199298 Oc1ccc2CCC(Cc2c1)N(CCCCNC(=O)c1ccccc1)CCCN1CCN(CC1)c1ccccc1 InChI=1S/C34H44N4O2/c39-33-17-15-28-14-16-32(26-30(28)27-33)37(20-8-7-18-35-34(40)29-10-3-1-4-11-29)21-9-19-36-22-24-38(25-23-36)31-12-5-2-6-13-31/h1-6,10-13,15,17,27,32,39H,7-9,14,16,18-26H2,(H,35,40) HYAIONDADCANQM-UHFFFAOYSA-N 50109924 CHEMBL156816::N-(4-{(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-[3-(4-phenyl-piperazin-1-yl)-propyl]-amino}-butyl)-benzamide D(2) dopamine receptor Homo sapiens 782.0 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371566 104004813 CHEMBL156816 ZINC13438599 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199299 Oc1ccc2CCC(Cc2c1)N(CCCN1CCN(CC1)c1ccccc1)CCNC(=O)c1ccccc1 InChI=1S/C32H40N4O2/c37-31-15-13-26-12-14-30(24-28(26)25-31)35(19-16-33-32(38)27-8-3-1-4-9-27)18-7-17-34-20-22-36(23-21-34)29-10-5-2-6-11-29/h1-6,8-11,13,15,25,30,37H,7,12,14,16-24H2,(H,33,38) RVFWCLJRIRUOIQ-UHFFFAOYSA-N 50109922 CHEMBL422883::N-(2-{(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-[3-(4-phenyl-piperazin-1-yl)-propyl]-amino}-ethyl)-benzamide D(2) dopamine receptor Homo sapiens 354 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109922&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371356 104004811 CHEMBL422883 ZINC13438606 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199302 Oc1ccc2CCC(Cc2c1)N(CCCCN1CCN(CC1)c1cccc(Cl)c1Cl)CC#C InChI=1S/C27H33Cl2N3O/c1-2-12-31(23-10-8-21-9-11-24(33)20-22(21)19-23)14-4-3-13-30-15-17-32(18-16-30)26-7-5-6-25(28)27(26)29/h1,5-7,9,11,20,23,33H,3-4,8,10,12-19H2 PIHOPECZMJBZBU-UHFFFAOYSA-N 50109925 7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-prop-2-ynyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL157035 D(2) dopamine receptor Homo sapiens 7.4 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109925&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22261340 104004814 CHEMBL157035 ZINC13438641 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199305 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2ccc(O)cc2C1 InChI=1S/C25H35N3O/c1-2-12-27(24-10-8-21-9-11-25(29)20-22(21)19-24)16-13-26-14-17-28(18-15-26)23-6-4-3-5-7-23/h3-7,9,11,20,24,29H,2,8,10,12-19H2,1H3 POVCSYONXDMZKL-UHFFFAOYSA-N 50109926 7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol::7-{[2-(4-Phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL156639 D(2) dopamine receptor Homo sapiens 213 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10178704 104004815 CHEMBL156639 ZINC22924460 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50207071 Oc1cc2OCC3NCc4ccccc4C3c2cc1O InChI=1S/C16H15NO3/c18-13-5-11-15(6-14(13)19)20-8-12-16(11)10-4-2-1-3-9(10)7-17-12/h1-6,12,16-19H,7-8H2 QDUNOUQOKOYLCH-UHFFFAOYSA-N 50200351 (+/-)-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline::CHEMBL217299 D(2) dopamine receptor Homo sapiens 3700 ChEMBL 10.1021/jm0604979 10.7270/Q25T3M92 17154515 Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25142456 104080715 CHEMBL217299 ZINC34801104 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199308 CCCN(CCN1CCN(CC1)c1cccc(Cl)c1Cl)C1CCc2ccc(O)cc2C1 InChI=1S/C25H33Cl2N3O/c1-2-10-29(21-8-6-19-7-9-22(31)18-20(19)17-21)14-11-28-12-15-30(16-13-28)24-5-3-4-23(26)25(24)27/h3-5,7,9,18,21,31H,2,6,8,10-17H2,1H3 QUMJJLZEFJECGH-UHFFFAOYSA-N 50109929 7-({2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL156689 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109929&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10479465 104004818 CHEMBL156689 ZINC22924469 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199309 CCCN(CCCCN1CCN(CC1)c1ccccc1)C1CCc2ccc(O)cc2C1 InChI=1S/C27H39N3O/c1-2-14-29(26-12-10-23-11-13-27(31)22-24(23)21-26)16-7-6-15-28-17-19-30(20-18-28)25-8-4-3-5-9-25/h3-5,8-9,11,13,22,26,31H,2,6-7,10,12,14-21H2,1H3 RURKEKYFHBYLDY-UHFFFAOYSA-N 50109927 (+)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-2-ol::(-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-2-ol::7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL155826 D(2) dopamine receptor Homo sapiens 114 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109927&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22261332 104004816 CHEMBL155826 ZINC13438629 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199310 Oc1ccc2CCC(Cc2c1)N(CCCC#N)CCCN1CCN(CC1)c1ccccc1 InChI=1S/C27H36N4O/c28-13-4-5-15-30(26-11-9-23-10-12-27(32)22-24(23)21-26)16-6-14-29-17-19-31(20-18-29)25-7-2-1-3-8-25/h1-3,7-8,10,12,22,26,32H,4-6,9,11,14-21H2 OSAUGWDHZYWLTI-UHFFFAOYSA-N 50109923 4-{(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-[3-(4-phenyl-piperazin-1-yl)-propyl]-amino}-butyronitrile::CHEMBL346512 D(2) dopamine receptor Homo sapiens 622 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371025 104004812 CHEMBL346512 ZINC13438591 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199312 Oc1ccc2CCC(Cc2c1)N(CCN1CCN(CC1)c1ccccc1)CC#C InChI=1S/C25H31N3O/c1-2-12-27(24-10-8-21-9-11-25(29)20-22(21)19-24)16-13-26-14-17-28(18-15-26)23-6-4-3-5-7-23/h1,3-7,9,11,20,24,29H,8,10,12-19H2 WMPBOLSQXBJOKQ-UHFFFAOYSA-N 50109928 7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-prop-2-ynyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL158013 D(2) dopamine receptor Homo sapiens 245 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109928&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10200368 104004817 CHEMBL158013 ZINC22924450 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199316 Oc1ccc2CCC(Cc2c1)N(CCCCN1CCN(CC1)c1ccccc1)CC#C InChI=1S/C27H35N3O/c1-2-14-29(26-12-10-23-11-13-27(31)22-24(23)21-26)16-7-6-15-28-17-19-30(20-18-28)25-8-4-3-5-9-25/h1,3-5,8-9,11,13,22,26,31H,6-7,10,12,14-21H2 LXFPKJLLIWPMEU-UHFFFAOYSA-N 50109931 (+)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-ynylamino}-5,6,7,8-tetrahydronaphthalen-2-ol::(-)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-ynylamino}-5,6,7,8-tetrahydronaphthalen-2-ol::7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL157293 D(2) dopamine receptor Homo sapiens 68 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109931&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10364677 104004820 CHEMBL157293 ZINC13438618 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50199317 CCCN(CCCCN1CCN(CC1)c1cccc(Cl)c1Cl)C1CCc2ccc(O)cc2C1 InChI=1S/C27H37Cl2N3O/c1-2-12-31(23-10-8-21-9-11-24(33)20-22(21)19-23)14-4-3-13-30-15-17-32(18-16-30)26-7-5-6-25(28)27(26)29/h5-7,9,11,20,23,33H,2-4,8,10,12-19H2,1H3 HUTRNXILWVFUDE-UHFFFAOYSA-N 50109930 7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL157036 D(2) dopamine receptor Homo sapiens 8.8 ChEMBL 10.1016/s0960-894x(01)00820-4 10.7270/Q25X287P 11844685 Dutta, AK; Fei, XS; Reith, ME Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10228202 104004819 CHEMBL157036 ZINC13438635 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223161 Cc1cccc2C(=O)N(CCCCCN3CCC(=CC3)c3c[nH]c4ccc(F)cc34)C(=O)c12 InChI=1S/C27H28FN3O2/c1-18-6-5-7-21-25(18)27(33)31(26(21)32)13-4-2-3-12-30-14-10-19(11-15-30)23-17-29-24-9-8-20(28)16-22(23)24/h5-10,16-17,29H,2-4,11-15H2,1H3 YPVDZKHCFQJIDP-UHFFFAOYSA-N 50123070 2-{5-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-4-methyl-isoindole-1,3-dione::CHEMBL335259 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123070&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353236 104015653 CHEMBL335259 ZINC27325057 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223162 Cc1ccc2C(=O)N(CCCCCN3CCC(=CC3)c3c[nH]c4ccc(F)cc34)C(=O)c2c1 InChI=1S/C27H28FN3O2/c1-18-5-7-21-23(15-18)27(33)31(26(21)32)12-4-2-3-11-30-13-9-19(10-14-30)24-17-29-25-8-6-20(28)16-22(24)25/h5-9,15-17,29H,2-4,10-14H2,1H3 QDSYGDXQPACKLI-UHFFFAOYSA-N 50123071 2-{5-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-5-methyl-isoindole-1,3-dione::CHEMBL340220 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353234 104015654 CHEMBL340220 ZINC27330058 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223164 Fc1ccc2C(=O)N(CCCCCN3CCC(=CC3)c3c[nH]c4ccc(F)cc34)C(=O)c2c1 InChI=1S/C26H25F2N3O2/c27-18-4-6-20-22(15-18)26(33)31(25(20)32)11-3-1-2-10-30-12-8-17(9-13-30)23-16-29-24-7-5-19(28)14-21(23)24/h4-8,14-16,29H,1-3,9-13H2 XPSGDPNMACULHA-UHFFFAOYSA-N 50123072 5-Fluoro-2-{5-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL336771 D(2) dopamine receptor Homo sapiens 10 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123072&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353445 104015655 CHEMBL336771 ZINC27407234 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223167 Cc1cccc2c(c[nH]c12)C1=CCN(CCCCCN2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C27H29N3O2/c1-19-8-7-11-21-24(18-28-25(19)21)20-12-16-29(17-13-20)14-5-2-6-15-30-26(31)22-9-3-4-10-23(22)27(30)32/h3-4,7-12,18,28H,2,5-6,13-17H2,1H3 RUNHZSVFEKDKRE-UHFFFAOYSA-N 50123074 2-{5-[4-(7-Methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL422618 D(2) dopamine receptor Homo sapiens 40 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123074&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353323 104015657 CHEMBL422618 ZINC27407826 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223168 Fc1ccc(cc1)C(=O)CCCN1CCC(CCc2c[nH]c3ccccc23)CC1 InChI=1S/C25H29FN2O/c26-22-11-9-20(10-12-22)25(29)6-3-15-28-16-13-19(14-17-28)7-8-21-18-27-24-5-2-1-4-23(21)24/h1-2,4-5,9-12,18-19,27H,3,6-8,13-17H2 DLNHKFQPIHQHPC-UHFFFAOYSA-N 50123073 1-(4-Fluoro-phenyl)-4-{4-[2-(1H-indol-3-yl)-ethyl]-piperidin-1-yl}-butan-1-one::CHEMBL423706 D(2) dopamine receptor Homo sapiens 40 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353343 104015656 CHEMBL423706 ZINC13487260 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223170 Fc1ccc2[nH]cc(C3=CCN(CCCCCN4C(=O)c5cccc(F)c5C4=O)CC3)c2c1 InChI=1S/C26H25F2N3O2/c27-18-7-8-23-20(15-18)21(16-29-23)17-9-13-30(14-10-17)11-2-1-3-12-31-25(32)19-5-4-6-22(28)24(19)26(31)33/h4-9,15-16,29H,1-3,10-14H2 ISWUHEUWAVWBQS-UHFFFAOYSA-N 50123075 4-Fluoro-2-{5-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL335844 D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123075&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353459 104015658 CHEMBL335844 ZINC27406257 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223172 Fc1ccc2C(=O)N(CCCCCN3CCC(=CC3)c3c[nH]c4ccccc34)C(=O)c2c1 InChI=1S/C26H26FN3O2/c27-19-8-9-21-22(16-19)26(32)30(25(21)31)13-5-1-4-12-29-14-10-18(11-15-29)23-17-28-24-7-3-2-6-20(23)24/h2-3,6-10,16-17,28H,1,4-5,11-15H2 FVDZPUYRYDLOSF-UHFFFAOYSA-N 50123077 5-Fluoro-2-{5-[4-(1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL421902 D(2) dopamine receptor Homo sapiens 40 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123077&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353492 104015660 CHEMBL421902 ZINC27327497 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223174 O=C1N(CCCCCN2CCC(=CC2)c2c[nH]c3ccccc23)C(=O)c2ccccc12 InChI=1S/C26H27N3O2/c30-25-21-9-2-3-10-22(21)26(31)29(25)15-7-1-6-14-28-16-12-19(13-17-28)23-18-27-24-11-5-4-8-20(23)24/h2-5,8-12,18,27H,1,6-7,13-17H2 MBMKBYGCQNWXCQ-UHFFFAOYSA-N 50123078 2-{5-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL414433 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123078&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353327 104015661 CHEMBL414433 ZINC27406581 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223175 C1CC(=CCN1)c1c[nH]c2ccccc12 InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2 CIRSPTXGPFAXRE-UHFFFAOYSA-N 31023 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole::CHEMBL2011570::CHEMBL27811::MLS000093715::SMR000029333::cid_2761023 D(2) dopamine receptor Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31023&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2761023 252615275 CHEMBL27811CHEMBL2011570 ZINC00154399 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218799 Cc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1 InChI=1S/C25H27N5/c1-19-9-10-22-21(18-19)25(28-23-8-5-12-26-24(23)27-22)30-16-14-29(15-17-30)13-11-20-6-3-2-4-7-20/h2-10,12,18H,11,13-17H2,1H3,(H,26,27) OCMWTQCINJDJDB-UHFFFAOYSA-N 50120921 8-Methyl-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL422310 D(2) dopamine receptor Homo sapiens 635 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11079832 104013874 CHEMBL422310 ZINC13492081 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218803 Cc1ccc2Nc3ncccc3N=C(NC3CCN(Cc4ccccc4)CC3)c2c1 InChI=1S/C25H27N5/c1-18-9-10-22-21(16-18)24(29-23-8-5-13-26-25(23)28-22)27-20-11-14-30(15-12-20)17-19-6-3-2-4-7-19/h2-10,13,16,20H,11-12,14-15,17H2,1H3,(H,26,28)(H,27,29) ZHPMNMWRUKIBHQ-UHFFFAOYSA-N 50120932 (1-Benzyl-piperidin-4-yl)-(8-methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-amine::CHEMBL358657 D(2) dopamine receptor Homo sapiens 183 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120932&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11014803 104013885 CHEMBL358657 ZINC13492088 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218808 Clc1ccc2Nc3ncccc3N=C(N3CCN(CC3)C3CCCCC3)c2c1 InChI=1S/C22H26ClN5/c23-16-8-9-19-18(15-16)22(26-20-7-4-10-24-21(20)25-19)28-13-11-27(12-14-28)17-5-2-1-3-6-17/h4,7-10,15,17H,1-3,5-6,11-14H2,(H,24,25) YQKVPKZIEDUDMI-UHFFFAOYSA-N 50120925 8-Chloro-6-(4-cyclohexyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL148559 D(2) dopamine receptor Homo sapiens 571 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120925&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11732013 104013878 CHEMBL148559 ZINC13492076 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50221005 CCCCCCN(CCc1ccccc1)CCc1cccc(O)c1 InChI=1S/C22H31NO/c1-2-3-4-8-16-23(17-14-20-10-6-5-7-11-20)18-15-21-12-9-13-22(24)19-21/h5-7,9-13,19,24H,2-4,8,14-18H2,1H3 XNXKEYCDXWQUQU-UHFFFAOYSA-N 50399884 CHEMBL2180641 D(2) dopamine receptor Homo sapiens 831 ChEMBL 10.1021/jm301258w 10.7270/Q24X58ZX 23134120 Spetea, M; Berzetei-Gurske, IP; Guerrieri, E; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71457372 163348908 CHEMBL2180641 ZINC95580346 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50221006 Oc1cccc(CCN(CCc2ccccc2)CC2CCC2)c1 InChI=1S/C21H27NO/c23-21-11-5-8-19(16-21)13-15-22(17-20-9-4-10-20)14-12-18-6-2-1-3-7-18/h1-3,5-8,11,16,20,23H,4,9-10,12-15,17H2 YNVKFHIWFDRVNY-UHFFFAOYSA-N 50399881 CHEMBL2180639 D(2) dopamine receptor Homo sapiens 450 ChEMBL 10.1021/jm301258w 10.7270/Q24X58ZX 23134120 Spetea, M; Berzetei-Gurske, IP; Guerrieri, E; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71452041 163348905 CHEMBL2180639 ZINC95576848 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50221007 Oc1cccc(CCN(CCc2ccccc2)CC2CC2)c1 InChI=1S/C20H25NO/c22-20-8-4-7-18(15-20)12-14-21(16-19-9-10-19)13-11-17-5-2-1-3-6-17/h1-8,15,19,22H,9-14,16H2 QURAQIGQNZYJHP-UHFFFAOYSA-N 50399882 CHEMBL2180638 D(2) dopamine receptor Homo sapiens 118 ChEMBL 10.1021/jm301258w 10.7270/Q24X58ZX 23134120 Spetea, M; Berzetei-Gurske, IP; Guerrieri, E; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399882&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71452040 163348906 CHEMBL2180638 ZINC95577917 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50221023 CCCCCCN(CCc1ccccc1)CCc1cccc(O)c1 InChI=1S/C22H31NO/c1-2-3-4-8-16-23(17-14-20-10-6-5-7-11-20)18-15-21-12-9-13-22(24)19-21/h5-7,9-13,19,24H,2-4,8,14-18H2,1H3 XNXKEYCDXWQUQU-UHFFFAOYSA-N 50399884 CHEMBL2180641 D(2) dopamine receptor Homo sapiens 1252 ChEMBL 10.1021/jm301258w 10.7270/Q24X58ZX 23134120 Spetea, M; Berzetei-Gurske, IP; Guerrieri, E; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71457372 163348908 CHEMBL2180641 ZINC95580346 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50221024 Oc1cccc(CCN(CCc2ccccc2)CC2CCC2)c1 InChI=1S/C21H27NO/c23-21-11-5-8-19(16-21)13-15-22(17-20-9-4-10-20)14-12-18-6-2-1-3-7-18/h1-3,5-8,11,16,20,23H,4,9-10,12-15,17H2 YNVKFHIWFDRVNY-UHFFFAOYSA-N 50399881 CHEMBL2180639 D(2) dopamine receptor Homo sapiens 1647 ChEMBL 10.1021/jm301258w 10.7270/Q24X58ZX 23134120 Spetea, M; Berzetei-Gurske, IP; Guerrieri, E; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71452041 163348905 CHEMBL2180639 ZINC95576848 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50221026 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Homo sapiens 422 ChEMBL 10.1021/jm301258w 10.7270/Q24X58ZX 23134120 Spetea, M; Berzetei-Gurske, IP; Guerrieri, E; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50221027 CCCN(CCc1ccccc1)CCc1cccc(O)c1 InChI=1S/C19H25NO/c1-2-13-20(14-11-17-7-4-3-5-8-17)15-12-18-9-6-10-19(21)16-18/h3-10,16,21H,2,11-15H2,1H3 QUZUPTMNMJTYGL-UHFFFAOYSA-N 50002310 3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydrobromide::CHEMBL1188090::CHEMBL545783 D(2) dopamine receptor Homo sapiens 39 ChEMBL 10.1021/jm301258w 10.7270/Q24X58ZX 23134120 Spetea, M; Berzetei-Gurske, IP; Guerrieri, E; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 114876 103916616 CHEMBL545783CHEMBL1188090 ZINC05833398 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50221031 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 19 ChEMBL 10.1021/jm301258w 10.7270/Q24X58ZX 23134120 Spetea, M; Berzetei-Gurske, IP; Guerrieri, E; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223176 Fc1ccc2[nH]cc(C3=CCN(CCCCCCCN4C(=O)c5ccccc5C4=O)CC3)c2c1 InChI=1S/C28H30FN3O2/c29-21-10-11-26-24(18-21)25(19-30-26)20-12-16-31(17-13-20)14-6-2-1-3-7-15-32-27(33)22-8-4-5-9-23(22)28(32)34/h4-5,8-12,18-19,30H,1-3,6-7,13-17H2 PJYMXWDDSLXHGG-UHFFFAOYSA-N 50123076 2-{7-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-heptyl}-isoindole-1,3-dione::CHEMBL338270 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123076&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353414 104015659 CHEMBL338270 ZINC27330886 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223177 Fc1ccc2[nH]cc(C3=CCN(CCCCN4C(=O)c5ccccc5C4=O)CC3)c2c1 InChI=1S/C25H24FN3O2/c26-18-7-8-23-21(15-18)22(16-27-23)17-9-13-28(14-10-17)11-3-4-12-29-24(30)19-5-1-2-6-20(19)25(29)31/h1-2,5-9,15-16,27H,3-4,10-14H2 NECJNLXOJRDELU-UHFFFAOYSA-N 50123069 2-(4-(4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)butyl)isoindoline-1,3-dione::2-{4-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-isoindole-1,3-dione::CHEMBL131495::SLV-310 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123069&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9888211 104015652 CHEMBL131495 ZINC01547791 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223181 Clc1ccc2[nH]cc(C3=CCN(CCCCCN4C(=O)c5ccccc5C4=O)CC3)c2c1 InChI=1S/C26H26ClN3O2/c27-19-8-9-24-22(16-19)23(17-28-24)18-10-14-29(15-11-18)12-4-1-5-13-30-25(31)20-6-2-3-7-21(20)26(30)32/h2-3,6-10,16-17,28H,1,4-5,11-15H2 RIJJQSBEJRHVSU-UHFFFAOYSA-N 50123079 2-{5-[4-(5-Chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL129979 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123079&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353233 104015662 CHEMBL129979 ZINC27330054 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223182 Fc1cccc2C(=O)N(CCCCCN3CCC(=CC3)c3c[nH]c4ccccc34)C(=O)c12 InChI=1S/C26H26FN3O2/c27-22-9-6-8-20-24(22)26(32)30(25(20)31)14-5-1-4-13-29-15-11-18(12-16-29)21-17-28-23-10-3-2-7-19(21)23/h2-3,6-11,17,28H,1,4-5,12-16H2 FVZDREXTEDTXIU-UHFFFAOYSA-N 50123081 4-Fluoro-2-{5-[4-(1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL339098 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123081&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353413 104015664 CHEMBL339098 ZINC27331801 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223190 Fc1ccc2[nH]cc(C3=CCN(CCCCCN4C(=O)c5ccccc5C4=O)CC3)c2c1 InChI=1S/C26H26FN3O2/c27-19-8-9-24-22(16-19)23(17-28-24)18-10-14-29(15-11-18)12-4-1-5-13-30-25(31)20-6-2-3-7-21(20)26(30)32/h2-3,6-10,16-17,28H,1,4-5,11-15H2 VURPIGYSDZFRHH-UHFFFAOYSA-N 50123082 2-{5-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL133524 D(2) dopamine receptor Homo sapiens 5 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123082&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10455444 104015665 CHEMBL133524 ZINC27405987 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223191 Fc1ccc2[nH]cc(C3=CCN(CCCN4C(=O)c5ccccc5C4=O)CC3)c2c1 InChI=1S/C24H22FN3O2/c25-17-6-7-22-20(14-17)21(15-26-22)16-8-12-27(13-9-16)10-3-11-28-23(29)18-4-1-2-5-19(18)24(28)30/h1-2,4-8,14-15,26H,3,9-13H2 MKIPKEANVGLYQX-UHFFFAOYSA-N 50123084 2-{3-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-isoindole-1,3-dione::CHEMBL334956 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123084&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9844106 104015667 CHEMBL334956 ZINC13487265 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223193 Cc1ccc2C(=O)N(CCCCCN3CCC(=CC3)c3c[nH]c4ccccc34)C(=O)c2c1 InChI=1S/C27H29N3O2/c1-19-9-10-22-23(17-19)27(32)30(26(22)31)14-6-2-5-13-29-15-11-20(12-16-29)24-18-28-25-8-4-3-7-21(24)25/h3-4,7-11,17-18,28H,2,5-6,12-16H2,1H3 MOJPVHLAGWNFCV-UHFFFAOYSA-N 50123083 2-{5-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-5-methyl-isoindole-1,3-dione::CHEMBL130261 D(2) dopamine receptor Homo sapiens 40 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123083&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353461 104015666 CHEMBL130261 ZINC27331865 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223194 Cc1cccc2C(=O)N(CCCCCN3CCC(=CC3)c3c[nH]c4ccccc34)C(=O)c12 InChI=1S/C27H29N3O2/c1-19-8-7-10-22-25(19)27(32)30(26(22)31)15-6-2-5-14-29-16-12-20(13-17-29)23-18-28-24-11-4-3-9-21(23)24/h3-4,7-12,18,28H,2,5-6,13-17H2,1H3 XRYOHUILNZTLBQ-UHFFFAOYSA-N 50123080 2-{5-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-pentyl}-4-methyl-isoindole-1,3-dione::CHEMBL129852 D(2) dopamine receptor Homo sapiens 100 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123080&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353462 104015663 CHEMBL129852 ZINC27331869 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223195 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 3 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223196 C(Cc1c[nH]c2ccccc12)C1CCNCC1 InChI=1S/C15H20N2/c1-2-4-15-14(3-1)13(11-17-15)6-5-12-7-9-16-10-8-12/h1-4,11-12,16-17H,5-10H2 SADQVAVFGNTEOD-UHFFFAOYSA-N 50029150 3-(2-Piperidin-4-yl-ethyl)-1H-indole::CHEMBL276520::Indalpine D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00996-4 10.7270/Q2Z89BSX 12565939 van Hes, R; Smid, P; Stroomer, CN; Tipker, K; Tulp, MT; van der Heyden, JA; McCreary, AC; Hesselink, MB; Kruse, CG Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44668 103938228 CHEMBL276520 DB08953 ZINC04674528 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218816 Cc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1 InChI=1S/C27H29N5/c1-18-9-12-24-23(14-18)26(31-25-8-5-13-28-27(25)30-24)29-20-15-21-10-11-22(16-20)32(21)17-19-6-3-2-4-7-19/h2-9,12-14,20-22H,10-11,15-17H2,1H3,(H,28,30)(H,29,31) LIBNJNRMHRQQCZ-UHFFFAOYSA-N 50120934 (8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-amine::CHEMBL148694 D(2) dopamine receptor Homo sapiens 149 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365419 104013887 CHEMBL148694 ZINC13492092 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218829 Clc1ccc2Nc3ncccc3N=C(N3CCN(Cc4ccccc4)CC3)c2c1 InChI=1S/C23H22ClN5/c24-18-8-9-20-19(15-18)23(27-21-7-4-10-25-22(21)26-20)29-13-11-28(12-14-29)16-17-5-2-1-3-6-17/h1-10,15H,11-14,16H2,(H,25,26) MVUVSHXUPTVDBC-UHFFFAOYSA-N 50120928 6-(4-Benzyl-piperazin-1-yl)-8-chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL146856 D(2) dopamine receptor Homo sapiens 9943 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120928&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10363821 104013881 CHEMBL146856 ZINC13492078 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218835 Clc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1 InChI=1S/C24H24ClN5/c25-19-8-9-21-20(17-19)24(28-22-7-4-11-26-23(22)27-21)30-15-13-29(14-16-30)12-10-18-5-2-1-3-6-18/h1-9,11,17H,10,12-16H2,(H,26,27) OGHDWFXSMLKLNB-UHFFFAOYSA-N 50120945 8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL436274 D(2) dopamine receptor Homo sapiens 892 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11058829 104013898 CHEMBL436274 ZINC13492080 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218842 CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(Cl)cc12 InChI=1S/C18H20ClN5/c1-24-9-6-13(7-10-24)21-17-14-11-12(19)4-5-15(14)22-18-16(23-17)3-2-8-20-18/h2-5,8,11,13H,6-7,9-10H2,1H3,(H,20,22)(H,21,23) YYFLIYHRHHWXBK-UHFFFAOYSA-N 50120941 (8-Chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-(1-methyl-piperidin-4-yl)-amine::CHEMBL356149 D(2) dopamine receptor Homo sapiens 1099 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10914810 104013894 CHEMBL356149 ZINC13492085 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218847 Clc1ccc2Nc3ncccc3N=C(NC3CCN(Cc4ccccc4)CC3)c2c1 InChI=1S/C24H24ClN5/c25-18-8-9-21-20(15-18)23(29-22-7-4-12-26-24(22)28-21)27-19-10-13-30(14-11-19)16-17-5-2-1-3-6-17/h1-9,12,15,19H,10-11,13-14,16H2,(H,26,28)(H,27,29) USKVYSVSXWHTPS-UHFFFAOYSA-N 50120939 (1-Benzyl-piperidin-4-yl)-(8-chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-amine::CHEMBL342536 D(2) dopamine receptor Homo sapiens 183 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10884257 104013892 CHEMBL342536 ZINC13492087 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218849 Clc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1 InChI=1S/C26H26ClN5/c27-18-8-11-23-22(13-18)25(31-24-7-4-12-28-26(24)30-23)29-19-14-20-9-10-21(15-19)32(20)16-17-5-2-1-3-6-17/h1-8,11-13,19-21H,9-10,14-16H2,(H,28,30)(H,29,31) JQCALUODVNXQRL-UHFFFAOYSA-N 50120938 (8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-amine::CHEMBL148353 D(2) dopamine receptor Homo sapiens 136 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365178 104013891 CHEMBL148353 ZINC13492090 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50218853 CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(C)cc12 InChI=1S/C19H23N5/c1-13-5-6-16-15(12-13)18(21-14-7-10-24(2)11-8-14)23-17-4-3-9-20-19(17)22-16/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,20,22)(H,21,23) NKNZUUWFOPEUNZ-UHFFFAOYSA-N 50120935 (8-Methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-(1-methyl-piperidin-4-yl)-amine::CHEMBL347959 D(2) dopamine receptor Homo sapiens 2596 ChEMBL 10.1021/jm0104825 10.7270/Q2571BC1 12408724 Liegeois, JF; Eyrolles, L; Ellenbroek, BA; Lejeune, C; Carato, P; Bruhwyler, J; Geczy, J; Damas, J; Delarge, J University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10925293 104013888 CHEMBL347959 ZINC13492086 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50211099 CCCN(CCC)[C@H]1CCc2nn3ccccc3c2C1 InChI=1S/C17H25N3/c1-3-10-19(11-4-2)14-8-9-16-15(13-14)17-7-5-6-12-20(17)18-16/h5-7,12,14H,3-4,8-11,13H2,1-2H3/t14-/m0/s1 PWWITWFCENNJEP-AWEZNQCLSA-N 50116767 CHEMBL310867::Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indazol-2-yl-amine D(2) dopamine receptor Homo sapiens 35 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116767&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084583 104010406 CHEMBL310867 ZINC13817114 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50211112 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50211113 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Homo sapiens 27 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50222362 CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3 UTMXFLLOSBJGIE-UHFFFAOYSA-N 50122716 5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahydro-benzo[h][1,6]naphthyridine::CHEMBL35226 D(2) dopamine receptor Homo sapiens 3400.0 ChEMBL 10.1021/jm020954v 10.7270/Q2J67G8P 12502367 Hinschberger, A; Butt, S; Lelong, V; Boulouard, M; Dumuis, A; Dauphin, F; Bureau, R; Pfeiffer, B; Renard, P; Rault, S Université de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9881053 104015356 CHEMBL35226 ZINC29233810 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225759 CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@@H]1CCC(=CC1)C#C InChI=1S/C24H30N2OS/c1-3-16-26(21-13-11-19(4-2)12-14-21)17-8-7-15-25-24(27)23-18-20-9-5-6-10-22(20)28-23/h2,5-6,9-11,18,21H,3,7-8,12-17H2,1H3,(H,25,27)/t21-/m0/s1 OVRYUDOMQFGLII-NRFANRHFSA-N 50436544 CHEMBL2397479 D(2) dopamine receptor Homo sapiens 3.1 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734031 175448861 CHEMBL2397479 ZINC96272461 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225761 CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@H]1CCC(=CC1)C#C InChI=1S/C24H30N2OS/c1-3-16-26(21-13-11-19(4-2)12-14-21)17-8-7-15-25-24(27)23-18-20-9-5-6-10-22(20)28-23/h2,5-6,9-11,18,21H,3,7-8,12-17H2,1H3,(H,25,27)/t21-/m1/s1 OVRYUDOMQFGLII-OAQYLSRUSA-N 50436543 CHEMBL2397480 D(2) dopamine receptor Homo sapiens 2 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734129 175448860 CHEMBL2397480 ZINC96272460 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50209103 Fc1ccc(cc1)-c1cncc(CNC[C@H]2CCc3ccccc3O2)c1 InChI=1S/C22H21FN2O/c23-20-8-5-17(6-9-20)19-11-16(12-24-14-19)13-25-15-21-10-7-18-3-1-2-4-22(18)26-21/h1-6,8-9,11-12,14,21,25H,7,10,13,15H2/t21-/m1/s1 HKFMQJUJWSFOLY-OAQYLSRUSA-N 50027256 Sarizotan D(2) dopamine receptor Homo sapiens <6 ChEMBL 10.1021/jm7009364 10.7270/Q25B039W 18181565 Cavalli, A; Bolognesi, ML; Minarini, A; Rosini, M; Tumiatti, V; Recanatini, M; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6918388 277286710 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225762 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1 PWZPBZQTTHOCIS-MHZLTWQESA-N 50436542 CHEMBL2397389 D(2) dopamine receptor Homo sapiens 0.600000 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436542&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71733932 175448859 CHEMBL2397389 ZINC40420921 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225764 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 260 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225769 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225777 CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@H]1CCC(=CC1)C#C InChI=1S/C24H30N2OS/c1-3-16-26(21-13-11-19(4-2)12-14-21)17-8-7-15-25-24(27)23-18-20-9-5-6-10-22(20)28-23/h2,5-6,9-11,18,21H,3,7-8,12-17H2,1H3,(H,25,27)/t21-/m1/s1 OVRYUDOMQFGLII-OAQYLSRUSA-N 50436543 CHEMBL2397480 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734129 175448860 CHEMBL2397480 ZINC96272460 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225778 CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@@H]1CCC(=CC1)C#C InChI=1S/C24H30N2OS/c1-3-16-26(21-13-11-19(4-2)12-14-21)17-8-7-15-25-24(27)23-18-20-9-5-6-10-22(20)28-23/h2,5-6,9-11,18,21H,3,7-8,12-17H2,1H3,(H,25,27)/t21-/m0/s1 OVRYUDOMQFGLII-NRFANRHFSA-N 50436544 CHEMBL2397479 D(2) dopamine receptor Homo sapiens 33 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734031 175448861 CHEMBL2397479 ZINC96272461 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225786 CCCN(CCCCNC(=O)c1cc2ccccn2n1)[C@H]1CCC(=CC1)C#C InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)22-18-21-9-5-7-17-27(21)25-22/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m1/s1 KVEHVMQJUPMJNA-HXUWFJFHSA-N 50436539 CHEMBL2397391 D(2) dopamine receptor Homo sapiens 66 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734126 175448856 CHEMBL2397391 ZINC96272458 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225787 CCCN(CCCCNC(=O)c1cnn2ccccc12)[C@H]1CCC(=CC1)C#C InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)21-18-25-27-17-7-5-9-22(21)27/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m1/s1 IDKIRFAIRCIGSS-HXUWFJFHSA-N 50436537 CHEMBL2397476 D(2) dopamine receptor Homo sapiens 1.1 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734127 175448854 CHEMBL2397476 ZINC96272456 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225788 CCCCn1ncc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCC(=CC2)C#C)n1 InChI=1S/C32H47N5O3/c1-5-8-22-37-34-25-28(35-37)12-11-23-40-30-18-15-27(24-31(30)39-4)32(38)33-19-9-10-21-36(20-6-2)29-16-13-26(7-3)14-17-29/h3,13,15,18,24-25,29H,5-6,8-12,14,16-17,19-23H2,1-2,4H3,(H,33,38)/t29-/m1/s1 HKOJNCZKZSYFEQ-GDLZYMKVSA-N 50436545 CHEMBL2397478 D(2) dopamine receptor Homo sapiens 6 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73347474 175448862 CHEMBL2397478 ZINC96272462 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225789 CCCN(CCCCNC(=O)c1cc2ccccn2n1)[C@@H]1CCC(=CC1)C#C InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)22-18-21-9-5-7-17-27(21)25-22/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m0/s1 KVEHVMQJUPMJNA-FQEVSTJZSA-N 50436540 CHEMBL2397390 D(2) dopamine receptor Homo sapiens 63 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436540&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734028 175448857 CHEMBL2397390 ZINC96272459 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225791 CCCCn1ncc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCC(=CC2)C#C)n1 InChI=1S/C32H47N5O3/c1-5-8-22-37-34-25-28(35-37)12-11-23-40-30-18-15-27(24-31(30)39-4)32(38)33-19-9-10-21-36(20-6-2)29-16-13-26(7-3)14-17-29/h3,13,15,18,24-25,29H,5-6,8-12,14,16-17,19-23H2,1-2,4H3,(H,33,38)/t29-/m1/s1 HKOJNCZKZSYFEQ-GDLZYMKVSA-N 50436545 CHEMBL2397478 D(2) dopamine receptor Homo sapiens 0.530000 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73347474 175448862 CHEMBL2397478 ZINC96272462 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225792 CCCN(CCCCNC(=O)c1cc2ccccn2n1)[C@@H]1CCC(=CC1)C#C InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)22-18-21-9-5-7-17-27(21)25-22/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m0/s1 KVEHVMQJUPMJNA-FQEVSTJZSA-N 50436540 CHEMBL2397390 D(2) dopamine receptor Homo sapiens 5.5 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436540&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734028 175448857 CHEMBL2397390 ZINC96272459 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225793 CCCN(CCCCNC(=O)c1cnn2ccccc12)[C@@H]1CCC(=CC1)C#C InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)21-18-25-27-17-7-5-9-22(21)27/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m0/s1 IDKIRFAIRCIGSS-FQEVSTJZSA-N 50436538 CHEMBL2397392 D(2) dopamine receptor Homo sapiens 7.1 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734029 175448855 CHEMBL2397392 ZINC96272457 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225794 CCCCn1ncc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCC(=CC2)C#C)n1 InChI=1S/C32H47N5O3/c1-5-8-22-37-34-25-28(35-37)12-11-23-40-30-18-15-27(24-31(30)39-4)32(38)33-19-9-10-21-36(20-6-2)29-16-13-26(7-3)14-17-29/h3,13,15,18,24-25,29H,5-6,8-12,14,16-17,19-23H2,1-2,4H3,(H,33,38)/t29-/m0/s1 HKOJNCZKZSYFEQ-LJAQVGFWSA-N 50436536 CHEMBL2397477 D(2) dopamine receptor Homo sapiens 4.2 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353534 175448853 CHEMBL2397477 ZINC96272455 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225795 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1 PWZPBZQTTHOCIS-HHHXNRCGSA-N 50436541 CHEMBL2396663 D(2) dopamine receptor Homo sapiens 1.2 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71733935 175448858 CHEMBL2396663 ZINC40420923 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216948 Clc1ccc(CN2CCN(CCN3c4ccccc4CS3(=O)=O)CC2)cc1 InChI=1S/C20H24ClN3O2S/c21-19-7-5-17(6-8-19)15-23-11-9-22(10-12-23)13-14-24-20-4-2-1-3-18(20)16-27(24,25)26/h1-8H,9-16H2 JLTHLGOLANXTDG-UHFFFAOYSA-N 50119883 1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethyl}-1,3-dihydro-benzo[c]isothiazole 2,2-dioxide::CHEMBL104800 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119883&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335991 104013010 CHEMBL104800 ZINC22941359 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216949 Clc1ccc(CN2CCN(CCn3c4ccccc4oc3=O)CC2)cc1 InChI=1S/C20H22ClN3O2/c21-17-7-5-16(6-8-17)15-23-11-9-22(10-12-23)13-14-24-18-3-1-2-4-19(18)26-20(24)25/h1-8H,9-15H2 IQYIVLCWFWBASZ-UHFFFAOYSA-N 50119884 3-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethyl}-3H-benzooxazol-2-one::CHEMBL104063 D(2) dopamine receptor Homo sapiens 8053 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 30616772 104013011 CHEMBL104063 ZINC22778559 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216952 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 InChI=1S/C23H29N3O/c1-18-7-9-20(10-8-18)16-24-11-13-25(14-12-24)17-23(27)26-19(2)15-21-5-3-4-6-22(21)26/h3-10,19H,11-17H2,1-2H3 BKDQVRCFIJMWOR-UHFFFAOYSA-N 50119892 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107742 D(2) dopamine receptor Homo sapiens 140 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119892&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9799123 104013019 CHEMBL107742 ZINC22941419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216954 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2cc(Cl)cc(Cl)c2)CC1 InChI=1S/C22H25Cl2N3O/c1-16-10-18-4-2-3-5-21(18)27(16)22(28)15-26-8-6-25(7-9-26)14-17-11-19(23)13-20(24)12-17/h2-5,11-13,16H,6-10,14-15H2,1H3 XKSRPDXBGYGWEX-UHFFFAOYSA-N 50119891 2-[4-(3,5-Dichloro-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107020 D(2) dopamine receptor Homo sapiens 214 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335907 104013018 CHEMBL107020 ZINC22941477 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216956 Clc1ccc(CN2CCN(CC(=O)N3CCCSc4ccccc34)CC2)cc1 InChI=1S/C22H26ClN3OS/c23-19-8-6-18(7-9-19)16-24-11-13-25(14-12-24)17-22(27)26-10-3-15-28-21-5-2-1-4-20(21)26/h1-2,4-9H,3,10-17H2 LZYZLDMCQNWMSS-UHFFFAOYSA-N 50119887 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(3,4-dihydro-2H-benzo[b][1,4]thiazepin-5-yl)-ethanone::CHEMBL106007 D(2) dopamine receptor Homo sapiens >5000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119887&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336085 104013014 CHEMBL106007 ZINC22941354 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216957 CC1(C)Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H28ClN3O/c1-23(2)15-19-5-3-4-6-21(19)27(23)22(28)17-26-13-11-25(12-14-26)16-18-7-9-20(24)10-8-18/h3-10H,11-17H2,1-2H3 MRQPAQHCUBEBQD-UHFFFAOYSA-N 50119888 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,2-dimethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL317879 D(2) dopamine receptor Homo sapiens 117 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9887091 104013015 CHEMBL317879 ZINC22941289 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216960 CSc1ccc2N(CCc2c1)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3OS/c1-28-20-6-7-21-18(14-20)8-9-26(21)22(27)16-25-12-10-24(11-13-25)15-17-2-4-19(23)5-3-17/h2-7,14H,8-13,15-16H2,1H3 IKNJXDNJONONKL-UHFFFAOYSA-N 50119895 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(5-methylsulfanyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL318760 D(2) dopamine receptor Homo sapiens 3780.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119895&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336194 104013022 CHEMBL318760 ZINC22941253 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216967 Clc1ccc(CN2CCN(CC(=O)N3CCc4ccc(Cl)cc34)CC2)cc1 InChI=1S/C21H23Cl2N3O/c22-18-4-1-16(2-5-18)14-24-9-11-25(12-10-24)15-21(27)26-8-7-17-3-6-19(23)13-20(17)26/h1-6,13H,7-12,14-15H2 YWWSNUCDECZHPM-UHFFFAOYSA-N 50119901 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(6-chloro-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL318739 D(2) dopamine receptor Homo sapiens 607 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119901&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865920 104013028 CHEMBL318739 ZINC22941231 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225826 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1 PWZPBZQTTHOCIS-MHZLTWQESA-N 50436542 CHEMBL2397389 D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436542&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71733932 175448859 CHEMBL2397389 ZINC40420921 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225851 CCCN(CCCCNC(=O)c1cnn2ccccc12)[C@@H]1CCC(=CC1)C#C InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)21-18-25-27-17-7-5-9-22(21)27/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m0/s1 IDKIRFAIRCIGSS-FQEVSTJZSA-N 50436538 CHEMBL2397392 D(2) dopamine receptor Homo sapiens 0.550000 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734029 175448855 CHEMBL2397392 ZINC96272457 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225855 CCCN(CCCCNC(=O)c1cc2ccccn2n1)[C@H]1CCC(=CC1)C#C InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)22-18-21-9-5-7-17-27(21)25-22/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m1/s1 KVEHVMQJUPMJNA-HXUWFJFHSA-N 50436539 CHEMBL2397391 D(2) dopamine receptor Homo sapiens 3.9 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734126 175448856 CHEMBL2397391 ZINC96272458 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225864 CCCCn1ncc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCC(=CC2)C#C)n1 InChI=1S/C32H47N5O3/c1-5-8-22-37-34-25-28(35-37)12-11-23-40-30-18-15-27(24-31(30)39-4)32(38)33-19-9-10-21-36(20-6-2)29-16-13-26(7-3)14-17-29/h3,13,15,18,24-25,29H,5-6,8-12,14,16-17,19-23H2,1-2,4H3,(H,33,38)/t29-/m0/s1 HKOJNCZKZSYFEQ-LJAQVGFWSA-N 50436536 CHEMBL2397477 D(2) dopamine receptor Homo sapiens 8 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353534 175448853 CHEMBL2397477 ZINC96272455 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225866 CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1 PWZPBZQTTHOCIS-HHHXNRCGSA-N 50436541 CHEMBL2396663 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71733935 175448858 CHEMBL2396663 ZINC40420923 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50225890 CCCN(CCCCNC(=O)c1cnn2ccccc12)[C@H]1CCC(=CC1)C#C InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)21-18-25-27-17-7-5-9-22(21)27/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m1/s1 IDKIRFAIRCIGSS-HXUWFJFHSA-N 50436537 CHEMBL2397476 D(2) dopamine receptor Homo sapiens 7.8 ChEMBL 10.1021/jm400520c 10.7270/Q2PR7XDM 23730937 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71734127 175448854 CHEMBL2397476 ZINC96272456 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216971 Clc1ccc(CN2CCN(CCN3C(=O)COc4ccccc34)CC2)cc1 InChI=1S/C21H24ClN3O2/c22-18-7-5-17(6-8-18)15-24-11-9-23(10-12-24)13-14-25-19-3-1-2-4-20(19)27-16-21(25)26/h1-8H,9-16H2 IYMCNOIVOYIUOJ-UHFFFAOYSA-N 50119886 4-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethyl}-4H-benzo[1,4]oxazin-3-one::CHEMBL108261 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119886&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335998 104013013 CHEMBL108261 ZINC22941368 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216972 CC1CN(C(=O)CN2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 InChI=1S/C22H26ClN3O/c1-17-14-26(21-5-3-2-4-20(17)21)22(27)16-25-12-10-24(11-13-25)15-18-6-8-19(23)9-7-18/h2-9,17H,10-16H2,1H3 RAUNEUBNNMZNDM-UHFFFAOYSA-N 50119890 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(3-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL320067 D(2) dopamine receptor Homo sapiens 4375 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9843032 104013017 CHEMBL320067 ZINC22941270 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216973 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccccc2C)CC1 InChI=1S/C23H29N3O/c1-18-7-3-4-9-21(18)16-24-11-13-25(14-12-24)17-23(27)26-19(2)15-20-8-5-6-10-22(20)26/h3-10,19H,11-17H2,1-2H3 FMBYZLSHWCEAOV-UHFFFAOYSA-N 50119889 2-[4-(2-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104256 D(2) dopamine receptor Homo sapiens 1530 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119889&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335798 104013016 CHEMBL104256 ZINC22941459 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216974 Clc1ccc(CN2CCN(CC(=O)N3CCCc4ccccc34)CC2)cc1 InChI=1S/C22H26ClN3O/c23-20-9-7-18(8-10-20)16-24-12-14-25(15-13-24)17-22(27)26-11-3-5-19-4-1-2-6-21(19)26/h1-2,4,6-10H,3,5,11-17H2 PFPMRAONSOVYMJ-UHFFFAOYSA-N 50119905 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(3,4-dihydro-2H-quinolin-1-yl)-ethanone::CHEMBL323537 D(2) dopamine receptor Homo sapiens 2629 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119905&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9843031 104013032 CHEMBL323537 ZINC22453005 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216977 CC1CC(C)(C)N(C(=O)CN2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 InChI=1S/C25H32ClN3O/c1-19-16-25(2,3)29(23-7-5-4-6-22(19)23)24(30)18-28-14-12-27(13-15-28)17-20-8-10-21(26)11-9-20/h4-11,19H,12-18H2,1-3H3 IHQUTAVKEAOLLM-UHFFFAOYSA-N 50119903 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,2,4-trimethyl-3,4-dihydro-2H-quinolin-1-yl)-ethanone::CHEMBL104160 D(2) dopamine receptor Homo sapiens 35 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119903&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335987 104013030 CHEMBL104160 ZINC22941333 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216979 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(C)c(F)c2)CC1 InChI=1S/C24H29FN2O/c1-17-7-8-20(14-22(17)25)16-26-11-9-19(10-12-26)15-24(28)27-18(2)13-21-5-3-4-6-23(21)27/h3-8,14,18-19H,9-13,15-16H2,1-2H3 KIWCIUSCRQIWET-UHFFFAOYSA-N 50119908 2-[1-(3-Fluoro-4-methyl-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104273 D(2) dopamine receptor Homo sapiens 23 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119908&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335739 104013035 CHEMBL104273 ZINC13860176 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216980 Clc1ccc(CN2CCN(CC(=O)N3[C@@H]4CCCC[C@@H]4c4ccccc34)CC2)cc1 InChI=1S/C25H30ClN3O/c26-20-11-9-19(10-12-20)17-27-13-15-28(16-14-27)18-25(30)29-23-7-3-1-5-21(23)22-6-2-4-8-24(22)29/h1,3,5,7,9-12,22,24H,2,4,6,8,13-18H2/t22-,24-/m1/s1 FNYJYFAJIFQJRG-ISKFKSNPSA-N 50119885 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(4aR,9aR)-1,2,3,4,4a,9a-hexahydro-carbazol-9-yl-ethanone::CHEMBL323213 D(2) dopamine receptor Homo sapiens 377 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336100 104013012 CHEMBL323213 ZINC22941315 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216984 CC(N1CCN(Cc2ccc(Cl)cc2)CC1)C(=O)N1CCc2ccccc12 InChI=1S/C22H26ClN3O/c1-17(22(27)26-11-10-19-4-2-3-5-21(19)26)25-14-12-24(13-15-25)16-18-6-8-20(23)9-7-18/h2-9,17H,10-16H2,1H3 GSKCAMDFDQFBQJ-UHFFFAOYSA-N 50119912 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-propan-1-one::CHEMBL324867 D(2) dopamine receptor Homo sapiens >7000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16277250 104013039 CHEMBL324867 ZINC21763181 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216985 COc1ccccc1CN1CCN(CC(=O)N2C(C)Cc3ccccc23)CC1 InChI=1S/C23H29N3O2/c1-18-15-19-7-3-5-9-21(19)26(18)23(27)17-25-13-11-24(12-14-25)16-20-8-4-6-10-22(20)28-2/h3-10,18H,11-17H2,1-2H3 RMVOSVURGLWXST-UHFFFAOYSA-N 50119913 2-[4-(2-Methoxy-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL321734 D(2) dopamine receptor Homo sapiens 225 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119913&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335761 104013040 CHEMBL321734 ZINC22941465 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216986 CC1CCc2cc(F)ccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H27ClFN3O/c1-17-2-5-19-14-21(25)8-9-22(19)28(17)23(29)16-27-12-10-26(11-13-27)15-18-3-6-20(24)7-4-18/h3-4,6-9,14,17H,2,5,10-13,15-16H2,1H3 KIXDFGLGWRVXHJ-UHFFFAOYSA-N 50119909 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-ethanone::CHEMBL107391 D(2) dopamine receptor Homo sapiens 2220.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119909&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336005 104013036 CHEMBL107391 ZINC22941327 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216990 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccccc2F)CC1 InChI=1S/C23H27FN2O/c1-17-14-19-6-3-5-9-22(19)26(17)23(27)15-18-10-12-25(13-11-18)16-20-7-2-4-8-21(20)24/h2-9,17-18H,10-16H2,1H3 PXRYUTZDJMDKAL-UHFFFAOYSA-N 50119915 2-[1-(2-Fluoro-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104155 D(2) dopamine receptor Homo sapiens 1414 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119915&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335678 104013042 CHEMBL104155 ZINC13860156 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216992 COc1cccc2N(CCc12)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O2/c1-28-21-4-2-3-20-19(21)9-10-26(20)22(27)16-25-13-11-24(12-14-25)15-17-5-7-18(23)8-6-17/h2-8H,9-16H2,1H3 GLQGPKHLGDLFOL-UHFFFAOYSA-N 50119918 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(4-methoxy-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL319650 D(2) dopamine receptor Homo sapiens 487 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336175 104013045 CHEMBL319650 ZINC22941250 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50216997 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(cc2)C(C)(C)C)CC1 InChI=1S/C26H35N3O/c1-20-17-22-7-5-6-8-24(22)29(20)25(30)19-28-15-13-27(14-16-28)18-21-9-11-23(12-10-21)26(2,3)4/h5-12,20H,13-19H2,1-4H3 JHLGZIBTXUVCIJ-UHFFFAOYSA-N 50119919 2-[4-(4-tert-Butyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL419916 D(2) dopamine receptor Homo sapiens 1918 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119919&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335828 104013046 CHEMBL419916 ZINC22941435 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217000 CC1N(C(=O)CN2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc2C1(C)C InChI=1S/C24H30ClN3O/c1-18-24(2,3)21-6-4-5-7-22(21)28(18)23(29)17-27-14-12-26(13-15-27)16-19-8-10-20(25)11-9-19/h4-11,18H,12-17H2,1-3H3 WIDARYDIQORZIK-UHFFFAOYSA-N 50119923 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,3,3-trimethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107384 D(2) dopamine receptor Homo sapiens 883 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336154 104013050 CHEMBL107384 ZINC22941312 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217001 C[C@@H]1[C@H](C)c2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H28ClN3O/c1-17-18(2)27(22-6-4-3-5-21(17)22)23(28)16-26-13-11-25(12-14-26)15-19-7-9-20(24)10-8-19/h3-10,17-18H,11-16H2,1-2H3/t17-,18+/m0/s1 PASKDVYJTCOFHQ-ZWKOTPCHSA-N 50119922 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-((2R,3R)-2,3-dimethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL326670 D(2) dopamine receptor Homo sapiens 120 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119922&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336051 104013049 CHEMBL326670 ZINC22941303 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217008 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 138 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217012 CC(C)CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C25H32ClN3O/c1-19(2)15-23-16-21-5-3-4-6-24(21)29(23)25(30)18-28-13-11-27(12-14-28)17-20-7-9-22(26)10-8-20/h3-10,19,23H,11-18H2,1-2H3 NPOJZRKINKCVTE-UHFFFAOYSA-N 50119928 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2-isobutyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104713 D(2) dopamine receptor Homo sapiens 341.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119928&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336105 104013055 CHEMBL104713 ZINC22941287 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217013 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(Cl)c2)CC1 InChI=1S/C23H27ClN2O/c1-17-13-20-6-2-3-8-22(20)26(17)23(27)15-18-9-11-25(12-10-18)16-19-5-4-7-21(24)14-19/h2-8,14,17-18H,9-13,15-16H2,1H3 URRXCOKWLLNWKL-UHFFFAOYSA-N 50119929 2-[1-(3-Chloro-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104832 D(2) dopamine receptor Homo sapiens 62 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119929&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335796 104013056 CHEMBL104832 ZINC13860164 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217022 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(F)cc2Cl)CC1 InChI=1S/C23H26ClFN2O/c1-16-12-18-4-2-3-5-22(18)27(16)23(28)13-17-8-10-26(11-9-17)15-19-6-7-20(25)14-21(19)24/h2-7,14,16-17H,8-13,15H2,1H3 DTUDHTHALDQUOS-UHFFFAOYSA-N 50119935 2-[1-(2-Chloro-4-fluoro-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL326202 D(2) dopamine receptor Homo sapiens 518 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336109 104013062 CHEMBL326202 ZINC13860178 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217028 C[C@@H]1CN(Cc2ccc(Cl)cc2)CCN1CC(=O)N1CCc2ccccc12 InChI=1S/C22H26ClN3O/c1-17-14-24(15-18-6-8-20(23)9-7-18)12-13-25(17)16-22(27)26-11-10-19-4-2-3-5-21(19)26/h2-9,17H,10-16H2,1H3/t17-/m1/s1 JAMGASWUKANWIE-QGZVFWFLSA-N 50119902 2-[(R)-4-(4-Chloro-benzyl)-2-methyl-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104399 D(2) dopamine receptor Homo sapiens 5839 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119902&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336036 104013029 CHEMBL104399 ZINC22941380 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217031 Clc1ccc(CN2CCN(CC(=O)N3CCOc4ccccc34)CC2)cc1 InChI=1S/C21H24ClN3O2/c22-18-7-5-17(6-8-18)15-23-9-11-24(12-10-23)16-21(26)25-13-14-27-20-4-2-1-3-19(20)25/h1-8H,9-16H2 GFOKGPPIAVDUEO-UHFFFAOYSA-N 50119940 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,3-dihydro-benzo[1,4]oxazin-4-yl)-ethanone::CHEMBL104196 D(2) dopamine receptor Homo sapiens 2610 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119940&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9843137 104013067 CHEMBL104196 ZINC22778509 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217035 [O-][N+](=O)c1ccc2CCN(C(=O)CN3CCN(Cc4ccc(Cl)cc4)CC3)c2c1 InChI=1S/C21H23ClN4O3/c22-18-4-1-16(2-5-18)14-23-9-11-24(12-10-23)15-21(27)25-8-7-17-3-6-19(26(28)29)13-20(17)25/h1-6,13H,7-12,14-15H2 GMYMGBFWJJHMIQ-UHFFFAOYSA-N 50119939 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(6-nitro-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105625 D(2) dopamine receptor Homo sapiens 450 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25895959 104013066 CHEMBL105625 ZINC13860067 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217036 Cc1ccc2CCN(C(=O)CN3CCN(Cc4ccc(Cl)cc4)CC3)c2c1 InChI=1S/C22H26ClN3O/c1-17-2-5-19-8-9-26(21(19)14-17)22(27)16-25-12-10-24(11-13-25)15-18-3-6-20(23)7-4-18/h2-7,14H,8-13,15-16H2,1H3 VKTGHZRAPAQUIZ-UHFFFAOYSA-N 50119907 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(6-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105595 D(2) dopamine receptor Homo sapiens 6357.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335979 104013034 CHEMBL105595 ZINC22941245 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50222611 COc1ccc(CC(C)NCC(O)c2ccc(O)c(NC=O)c2)cc1 InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22) BPZSYCZIITTYBL-UHFFFAOYSA-N 86453 CAS_73573-87-2::Formoterol::NSC_3083544 D(2) dopamine receptor Homo sapiens <10000 ChEMBL 10.1016/j.bmcl.2011.05.097 10.7270/Q2QV3NS2 21723724 Connolly, S; Alcaraz, L; Bailey, A; Cadogan, E; Christie, J; Cook, AR; Fisher, AJ; Hill, S; Humphries, A; Ingall, AH; Kane, Z; Paine, S; Pairaudeau, G; Stocks, MJ; Young, A AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search FVN 3410 136352502 63082 DB00983 C06049 ZINC02599970 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217041 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(C)c(C)c2)CC1 InChI=1S/C25H32N2O/c1-18-8-9-22(14-19(18)2)17-26-12-10-21(11-13-26)16-25(28)27-20(3)15-23-6-4-5-7-24(23)27/h4-9,14,20-21H,10-13,15-17H2,1-3H3 IJOCAJHKCOKPFB-UHFFFAOYSA-N 50119894 2-[1-(3,4-Dimethyl-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106742 D(2) dopamine receptor Homo sapiens 306 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119894&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336050 104013021 CHEMBL106742 ZINC13860174 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217042 CC1CCc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H28ClN3O/c1-18-6-9-20-4-2-3-5-22(20)27(18)23(28)17-26-14-12-25(13-15-26)16-19-7-10-21(24)11-8-19/h2-5,7-8,10-11,18H,6,9,12-17H2,1H3 UFBREGGYAJBGQB-UHFFFAOYSA-N 50119917 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2-methyl-3,4-dihydro-2H-quinolin-1-yl)-ethanone::CHEMBL106897 D(2) dopamine receptor Homo sapiens 4126.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336055 104013044 CHEMBL106897 ZINC22941321 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217043 Clc1ccc(CN2CCN(CCN3C(=O)Cc4ccccc34)CC2)cc1 InChI=1S/C21H24ClN3O/c22-19-7-5-17(6-8-19)16-24-11-9-23(10-12-24)13-14-25-20-4-2-1-3-18(20)15-21(25)26/h1-8H,9-16H2 SILRNATUEGXXED-UHFFFAOYSA-N 50119906 1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethyl}-1,3-dihydro-indol-2-one::CHEMBL322326 D(2) dopamine receptor Homo sapiens 1642 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119906&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336314 104013033 CHEMBL322326 ZINC22941357 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217045 C[C@H]1CN(CC(=O)N2CCc3ccccc23)C[C@@H](C)N1Cc1ccc(Cl)cc1 InChI=1S/C23H28ClN3O/c1-17-13-25(14-18(2)27(17)15-19-7-9-21(24)10-8-19)16-23(28)26-12-11-20-5-3-4-6-22(20)26/h3-10,17-18H,11-16H2,1-2H3/t17-,18+ TTZNELRVLAJFTQ-HDICACEKSA-N 50119943 2-[(3S,5R)-4-(4-Chloro-benzyl)-3,5-dimethyl-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104756 D(2) dopamine receptor Homo sapiens 8620.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336045 104013070 CHEMBL104756 ZINC22941374 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217049 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(C)cc2)CC1 InChI=1S/C24H30N2O/c1-18-7-9-21(10-8-18)17-25-13-11-20(12-14-25)16-24(27)26-19(2)15-22-5-3-4-6-23(22)26/h3-10,19-20H,11-17H2,1-2H3 JUCOWYBTHHKLNZ-UHFFFAOYSA-N 50119898 2-[1-(4-Methyl-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104716 D(2) dopamine receptor Homo sapiens 39 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119898&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335812 104013025 CHEMBL104716 ZINC13860168 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217058 C[C@H]1CN(Cc2ccc(Cl)cc2)[C@H](C)CN1CC(=O)N1CCc2ccccc12 InChI=1S/C23H28ClN3O/c1-17-14-26(16-23(28)27-12-11-20-5-3-4-6-22(20)27)18(2)13-25(17)15-19-7-9-21(24)10-8-19/h3-10,17-18H,11-16H2,1-2H3/t17-,18+/m1/s1 QIYZNMOVNYQQHC-MSOLQXFVSA-N 50119936 2-[(2S,5R)-4-(4-Chloro-benzyl)-2,5-dimethyl-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107351 D(2) dopamine receptor Homo sapiens 6740 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119936&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336052 104013063 CHEMBL107351 ZINC26842028 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217062 CC(C)C1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C24H30ClN3O/c1-18(2)23-15-20-5-3-4-6-22(20)28(23)24(29)17-27-13-11-26(12-14-27)16-19-7-9-21(25)10-8-19/h3-10,18,23H,11-17H2,1-2H3 GLZPLACVFCDCPW-UHFFFAOYSA-N 50119952 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2-isopropyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL321871 D(2) dopamine receptor Homo sapiens 2524.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336127 104013079 CHEMBL321871 ZINC22941281 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217071 Cc1ccc2N(CCc2c1)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O/c1-17-2-7-21-19(14-17)8-9-26(21)22(27)16-25-12-10-24(11-13-25)15-18-3-5-20(23)6-4-18/h2-7,14H,8-13,15-16H2,1H3 IMIITABQEXKZPN-UHFFFAOYSA-N 50119944 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(5-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106998 D(2) dopamine receptor Homo sapiens 1692 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335896 104013071 CHEMBL106998 ZINC22941242 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217074 Clc1ccc(CN2CCN(CCn3c4ccccc4sc3=O)CC2)cc1 InChI=1S/C20H22ClN3OS/c21-17-7-5-16(6-8-17)15-23-11-9-22(10-12-23)13-14-24-18-3-1-2-4-19(18)26-20(24)25/h1-8H,9-15H2 ITCMJTMRLFGAKW-UHFFFAOYSA-N 50119932 3-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethyl}-3H-benzothiazol-2-one::CHEMBL108157 D(2) dopamine receptor Homo sapiens 1207 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119932&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336006 104013059 CHEMBL108157 ZINC22941365 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217076 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(F)cc2)CC1 InChI=1S/C22H26FN3O/c1-17-14-19-4-2-3-5-21(19)26(17)22(27)16-25-12-10-24(11-13-25)15-18-6-8-20(23)9-7-18/h2-9,17H,10-16H2,1H3 MKNRXBPDERAOEB-UHFFFAOYSA-N 50119949 2-[4-(4-Fluoro-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104614 D(2) dopamine receptor Homo sapiens 887.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335924 104013076 CHEMBL104614 ZINC22941413 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217078 CCC1(CC)Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C25H32ClN3O/c1-3-25(4-2)17-21-7-5-6-8-23(21)29(25)24(30)19-28-15-13-27(14-16-28)18-20-9-11-22(26)12-10-20/h5-12H,3-4,13-19H2,1-2H3 WEWHUBNHAHEDPL-UHFFFAOYSA-N 50119882 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,2-diethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL326250 D(2) dopamine receptor Homo sapiens 129 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119882&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336352 104013009 CHEMBL326250 ZINC22941292 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217079 Clc1ccc(CN2CCN(CC(=O)N3CCc4ccccc34)CC2)cc1 InChI=1S/C21H24ClN3O/c22-19-7-5-17(6-8-19)15-23-11-13-24(14-12-23)16-21(26)25-10-9-18-3-1-2-4-20(18)25/h1-8H,9-16H2 UHEJJZNLPMHGJA-UHFFFAOYSA-N 50092053 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-ethanone::CHEMBL69584 D(2) dopamine receptor Homo sapiens 690 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9104271 103990265 CHEMBL69584 ZINC21763183 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217081 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(cc2)C(F)(F)F)CC1 InChI=1S/C23H26F3N3O/c1-17-14-19-4-2-3-5-21(19)29(17)22(30)16-28-12-10-27(11-13-28)15-18-6-8-20(9-7-18)23(24,25)26/h2-9,17H,10-16H2,1H3 MHVPLSWUUSVXMG-UHFFFAOYSA-N 50119916 1-(2-Methyl-2,3-dihydro-indol-1-yl)-2-[4-(4-trifluoromethyl-benzyl)-piperazin-1-yl]-ethanone::CHEMBL104321 D(2) dopamine receptor Homo sapiens 5287.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119916&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335853 104013043 CHEMBL104321 ZINC22941441 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217083 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2cccc(OC(F)(F)F)c2)CC1 InChI=1S/C23H26F3N3O2/c1-17-13-19-6-2-3-8-21(19)29(17)22(30)16-28-11-9-27(10-12-28)15-18-5-4-7-20(14-18)31-23(24,25)26/h2-8,14,17H,9-13,15-16H2,1H3 IXMZAEHXCUOHCK-UHFFFAOYSA-N 50119951 1-(2-Methyl-2,3-dihydro-indol-1-yl)-2-[4-(3-trifluoromethoxy-benzyl)-piperazin-1-yl]-ethanone::CHEMBL419908 D(2) dopamine receptor Homo sapiens 620 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335799 104013078 CHEMBL419908 ZINC22941453 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217085 CN(C)S(=O)(=O)c1ccc2N(CCc2c1)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H29ClN4O3S/c1-25(2)32(30,31)21-7-8-22-19(15-21)9-10-28(22)23(29)17-27-13-11-26(12-14-27)16-18-3-5-20(24)6-4-18/h3-8,15H,9-14,16-17H2,1-2H3 HBHUBMJSJZYOOE-UHFFFAOYSA-N 50119955 1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-acetyl}-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide::CHEMBL106917 D(2) dopamine receptor Homo sapiens 3780.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336172 104013082 CHEMBL106917 ZINC22941256 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217092 CCC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H28ClN3O/c1-2-21-15-19-5-3-4-6-22(19)27(21)23(28)17-26-13-11-25(12-14-26)16-18-7-9-20(24)10-8-18/h3-10,21H,2,11-17H2,1H3 GGLGRTJZXPCWNM-UHFFFAOYSA-N 50119947 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2-ethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107793 D(2) dopamine receptor Homo sapiens 509 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336108 104013074 CHEMBL107793 ZINC22941276 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217093 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2cc(F)cc(F)c2)CC1 InChI=1S/C22H25F2N3O/c1-16-10-18-4-2-3-5-21(18)27(16)22(28)15-26-8-6-25(7-9-26)14-17-11-19(23)13-20(24)12-17/h2-5,11-13,16H,6-10,14-15H2,1H3 PXSNASRAIMXQPZ-UHFFFAOYSA-N 50119921 2-[4-(3,5-Difluoro-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107804 D(2) dopamine receptor Homo sapiens 3011 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335746 104013048 CHEMBL107804 ZINC22941471 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217095 Fc1cccc2N(CCc12)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C21H23ClFN3O/c22-17-6-4-16(5-7-17)14-24-10-12-25(13-11-24)15-21(27)26-9-8-18-19(23)2-1-3-20(18)26/h1-7H,8-15H2 XAJRENDYYQHIBY-UHFFFAOYSA-N 50119954 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(4-fluoro-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104432 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952218 104013081 CHEMBL104432 ZINC22941234 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217097 Clc1ccc(CN2CCN(CC2)C(=O)N2CCc3ccccc23)cc1 InChI=1S/C20H22ClN3O/c21-18-7-5-16(6-8-18)15-22-11-13-23(14-12-22)20(25)24-10-9-17-3-1-2-4-19(17)24/h1-8H,9-15H2 WKOOBVWHTGPRJA-UHFFFAOYSA-N 50119897 CHEMBL419911::[4-(4-Chloro-benzyl)-piperazin-1-yl]-(2,3-dihydro-indol-1-yl)-methanone D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119897&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336059 104013024 CHEMBL419911 ZINC13860108 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217098 Clc1ccc(CN2CCN(CC(=O)N3CCc4c3cccc4Cl)CC2)cc1 InChI=1S/C21H23Cl2N3O/c22-17-6-4-16(5-7-17)14-24-10-12-25(13-11-24)15-21(27)26-9-8-18-19(23)2-1-3-20(18)26/h1-7H,8-15H2 CUILJUVWLOGVCM-UHFFFAOYSA-N 50119941 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(4-chloro-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106598 D(2) dopamine receptor Homo sapiens 2145 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336035 104013068 CHEMBL106598 ZINC22941227 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217101 CC(N1CCN(CC(=O)N2C(C)Cc3ccccc23)CC1)c1ccc(Cl)cc1 InChI=1S/C23H28ClN3O/c1-17-15-20-5-3-4-6-22(20)27(17)23(28)16-25-11-13-26(14-12-25)18(2)19-7-9-21(24)10-8-19/h3-10,17-18H,11-16H2,1-2H3 MPGMPOGACCSYRN-UHFFFAOYSA-N 50119881 2-{4-[1-(4-Chloro-phenyl)-ethyl]-piperazin-1-yl}-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106751 D(2) dopamine receptor Homo sapiens 1252 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335971 104013008 CHEMBL106751 ZINC22941396 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217105 Clc1ccc(CN2CCN(CC2)C(=O)CN2CCc3ccccc23)cc1 InChI=1S/C21H24ClN3O/c22-19-7-5-17(6-8-19)15-23-11-13-24(14-12-23)21(26)16-25-10-9-18-3-1-2-4-20(18)25/h1-8H,9-16H2 YYGBJEARVDBSJM-UHFFFAOYSA-N 50119914 1-[4-(4-Chloro-benzyl)-piperazin-1-yl]-2-(2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104514 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9907381 104013041 CHEMBL104514 ZINC13860102 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217107 Clc1ccc(CN2CCN(CC(=O)N3c4ccccc4CC33CCCC3)CC2)cc1 InChI=1S/C25H30ClN3O/c26-22-9-7-20(8-10-22)18-27-13-15-28(16-14-27)19-24(30)29-23-6-2-1-5-21(23)17-25(29)11-3-4-12-25/h1-2,5-10H,3-4,11-19H2 UXSXSSBOLOHWNU-UHFFFAOYSA-N 50119931 2-[4-(4-chlorobenzyl)hexahydro-1-pyrazinyl]-1-spiro[cyclopentane-1,2'-(2',3'-dihydro-1'H-indole)]-1-yl-1-ethanone::CHEMBL441274 D(2) dopamine receptor Homo sapiens 187 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119931&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9867004 104013058 CHEMBL441274 ZINC22941296 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217108 CC1Cc2ccccc2N1C(=O)CN1CCN(CCc2ccc(Cl)cc2)CC1 InChI=1S/C23H28ClN3O/c1-18-16-20-4-2-3-5-22(20)27(18)23(28)17-26-14-12-25(13-15-26)11-10-19-6-8-21(24)9-7-19/h2-9,18H,10-17H2,1H3 MKIYNFAWYNPOJY-UHFFFAOYSA-N 50119904 2-{4-[2-(4-Chloro-phenyl)-ethyl]-piperazin-1-yl}-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL323022 D(2) dopamine receptor Homo sapiens 5247 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119904&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335972 104013031 CHEMBL323022 ZINC22812805 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217111 Clc1ccc(CN2CCN(CC(=O)N3CCCC4CCCCC34)CC2)cc1 InChI=1S/C22H32ClN3O/c23-20-9-7-18(8-10-20)16-24-12-14-25(15-13-24)17-22(27)26-11-3-5-19-4-1-2-6-21(19)26/h7-10,19,21H,1-6,11-17H2 WIBZNJPNKFYUFU-UHFFFAOYSA-N 50119937 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(octahydro-quinolin-1-yl)-ethanone::CHEMBL107755 D(2) dopamine receptor Homo sapiens 5847 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119937&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336003 104013064 CHEMBL107755 ZINC22941351 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217113 COc1ccc(CN2CCN(CC(=O)N3C(C)Cc4ccccc34)CC2)cc1 InChI=1S/C23H29N3O2/c1-18-15-20-5-3-4-6-22(20)26(18)23(27)17-25-13-11-24(12-14-25)16-19-7-9-21(28-2)10-8-19/h3-10,18H,11-17H2,1-2H3 DSNCXRXGMZSRBV-UHFFFAOYSA-N 50119960 2-[4-(4-Methoxy-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL323525 D(2) dopamine receptor Homo sapiens 2094 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335800 104013087 CHEMBL323525 ZINC22808916 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217118 COc1ccc(CN2CCC(CC(=O)N3C(C)Cc4ccccc34)CC2)cc1 InChI=1S/C24H30N2O2/c1-18-15-21-5-3-4-6-23(21)26(18)24(27)16-19-11-13-25(14-12-19)17-20-7-9-22(28-2)10-8-20/h3-10,18-19H,11-17H2,1-2H3 YNUOGMCLPCOTIC-UHFFFAOYSA-N 50119958 2-[1-(4-Methoxy-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104579 D(2) dopamine receptor Homo sapiens 158 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336075 104013085 CHEMBL104579 ZINC13860170 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217120 C[C@@H]1CN(Cc2ccc(Cl)cc2)CC[N@@+]1(C)CC(=O)N1CCc2ccccc12 InChI=1S/C23H29ClN3O/c1-18-15-25(16-19-7-9-21(24)10-8-19)13-14-27(18,2)17-23(28)26-12-11-20-5-3-4-6-22(20)26/h3-10,18H,11-17H2,1-2H3/q+1/t18-,27+/m1/s1 IZWDJSXJHNPRDP-CLYVBNDRSA-N 50119950 (1S,2R)-4-(4-Chloro-benzyl)-1-[2-(2,3-dihydro-indol-1-yl)-2-oxo-ethyl]-1,2-dimethyl-piperazin-1-ium::CHEMBL104138 D(2) dopamine receptor Homo sapiens 4742 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336046 104013077 CHEMBL104138 ZINC13860114 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217122 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(cc2)[N+]([O-])=O)CC1 InChI=1S/C23H27N3O3/c1-17-14-20-4-2-3-5-22(20)25(17)23(27)15-18-10-12-24(13-11-18)16-19-6-8-21(9-7-19)26(28)29/h2-9,17-18H,10-16H2,1H3 NHMWBCWXDURPQX-UHFFFAOYSA-N 50119934 1-(2-Methyl-2,3-dihydro-indol-1-yl)-2-[1-(4-nitro-benzyl)-piperidin-4-yl]-ethanone::CHEMBL104497 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336074 104013061 CHEMBL104497 ZINC13860172 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217123 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(F)c2)CC1 InChI=1S/C23H27FN2O/c1-17-13-20-6-2-3-8-22(20)26(17)23(27)15-18-9-11-25(12-10-18)16-19-5-4-7-21(24)14-19/h2-8,14,17-18H,9-13,15-16H2,1H3 HELOJRWGEVUNRF-UHFFFAOYSA-N 50119927 2-[1-(3-Fluoro-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104719 D(2) dopamine receptor Homo sapiens 52 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119927&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335886 104013054 CHEMBL104719 ZINC13860158 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217128 [O-][N+](=O)c1ccc2N(CCc2c1)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C21H23ClN4O3/c22-18-3-1-16(2-4-18)14-23-9-11-24(12-10-23)15-21(27)25-8-7-17-13-19(26(28)29)5-6-20(17)25/h1-6,13H,7-12,14-15H2 JJUKSUFNDXYVBQ-UHFFFAOYSA-N 50119896 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(5-nitro-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104251 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119896&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25895957 104013023 CHEMBL104251 ZINC13860066 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217129 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(F)cc2)CC1 InChI=1S/C23H27FN2O/c1-17-14-20-4-2-3-5-22(20)26(17)23(27)15-18-10-12-25(13-11-18)16-19-6-8-21(24)9-7-19/h2-9,17-18H,10-16H2,1H3 YZIQGQQLUDYLKK-UHFFFAOYSA-N 50119910 2-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL419356 D(2) dopamine receptor Homo sapiens 71 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119910&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335884 104013037 CHEMBL419356 ZINC13860160 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217130 Clc1ccc(CN2CCN(CC(=O)N3CCSc4ccccc34)CC2)cc1 InChI=1S/C21H24ClN3OS/c22-18-7-5-17(6-8-18)15-23-9-11-24(12-10-23)16-21(26)25-13-14-27-20-4-2-1-3-19(20)25/h1-8H,9-16H2 OTFXBGZPWISICK-UHFFFAOYSA-N 50119957 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,3-dihydro-benzo[1,4]thiazin-4-yl)-ethanone::CHEMBL104238 D(2) dopamine receptor Homo sapiens >10000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9909055 104013084 CHEMBL104238 ZINC22453001 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217132 Clc1ccc(CN2CCN(CCC(=O)N3CCc4ccccc34)CC2)cc1 InChI=1S/C22H26ClN3O/c23-20-7-5-18(6-8-20)17-25-15-13-24(14-16-25)11-10-22(27)26-12-9-19-3-1-2-4-21(19)26/h1-8H,9-17H2 COZFSYRFFSZJDT-UHFFFAOYSA-N 50119948 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-propan-1-one::CHEMBL104498 D(2) dopamine receptor Homo sapiens 5847 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 30743524 104013075 CHEMBL104498 ZINC22941371 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217133 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(C)c2)CC1 InChI=1S/C24H30N2O/c1-18-6-5-7-21(14-18)17-25-12-10-20(11-13-25)16-24(27)26-19(2)15-22-8-3-4-9-23(22)26/h3-9,14,19-20H,10-13,15-17H2,1-2H3 RYPURVOUHFFJCE-UHFFFAOYSA-N 50119945 2-[1-(3-Methyl-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105011 D(2) dopamine receptor Homo sapiens 166 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335795 104013072 CHEMBL105011 ZINC13860166 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217135 Cc1cccc2N(CCc12)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O/c1-17-3-2-4-21-20(17)9-10-26(21)22(27)16-25-13-11-24(12-14-25)15-18-5-7-19(23)8-6-18/h2-8H,9-16H2,1H3 FMTZLPYHNXPXCD-UHFFFAOYSA-N 50119956 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(4-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL321058 D(2) dopamine receptor Homo sapiens 3431 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335722 104013083 CHEMBL321058 ZINC22941240 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217140 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccccc2Cl)CC1 InChI=1S/C23H27ClN2O/c1-17-14-19-6-3-5-9-22(19)26(17)23(27)15-18-10-12-25(13-11-18)16-20-7-2-4-8-21(20)24/h2-9,17-18H,10-16H2,1H3 XORPIXFTSZPDAY-UHFFFAOYSA-N 50119946 2-[1-(2-Chloro-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106914 D(2) dopamine receptor Homo sapiens 834 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335813 104013073 CHEMBL106914 ZINC13860162 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217141 Fc1ccc2CCN(C(=O)CN3CCN(Cc4ccc(Cl)cc4)CC3)c2c1 InChI=1S/C21H23ClFN3O/c22-18-4-1-16(2-5-18)14-24-9-11-25(12-10-24)15-21(27)26-8-7-17-3-6-19(23)13-20(17)26/h1-6,13H,7-12,14-15H2 YVRKSLRZRXECRK-UHFFFAOYSA-N 50119959 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(6-fluoro-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL317266 D(2) dopamine receptor Homo sapiens 2552 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335721 104013086 CHEMBL317266 ZINC22941237 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217143 CC(C)c1ccc(CN2CCN(CC(=O)N3C(C)Cc4ccccc34)CC2)cc1 InChI=1S/C25H33N3O/c1-19(2)22-10-8-21(9-11-22)17-26-12-14-27(15-13-26)18-25(29)28-20(3)16-23-6-4-5-7-24(23)28/h4-11,19-20H,12-18H2,1-3H3 RCQMBKDEEJPXIY-UHFFFAOYSA-N 50119899 2-[4-(4-Isopropyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL320440 D(2) dopamine receptor Homo sapiens 1784 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119899&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335829 104013026 CHEMBL320440 ZINC22941430 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217147 C[C@@H]1CN(CC(=O)N2CCc3ccccc23)CCN1Cc1ccc(Cl)cc1 InChI=1S/C22H26ClN3O/c1-17-14-24(12-13-25(17)15-18-6-8-20(23)9-7-18)16-22(27)26-11-10-19-4-2-3-5-21(19)26/h2-9,17H,10-16H2,1H3/t17-/m1/s1 QQBINOQKHPXQEW-QGZVFWFLSA-N 50119962 2-[(R)-4-(4-Chloro-benzyl)-3-methyl-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106067 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336018 104013089 CHEMBL106067 ZINC22941383 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217149 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(OC(F)(F)F)cc2)CC1 InChI=1S/C23H26F3N3O2/c1-17-14-19-4-2-3-5-21(19)29(17)22(30)16-28-12-10-27(11-13-28)15-18-6-8-20(9-7-18)31-23(24,25)26/h2-9,17H,10-16H2,1H3 WSHBIOWJEQBSLU-UHFFFAOYSA-N 50119920 1-(2-Methyl-2,3-dihydro-indol-1-yl)-2-[4-(4-trifluoromethoxy-benzyl)-piperazin-1-yl]-ethanone::CHEMBL106208 D(2) dopamine receptor Homo sapiens 3823 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335816 104013047 CHEMBL106208 ZINC22941447 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217150 CC1Cc2ccccc2N1C(=O)CN1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1 InChI=1S/C28H30ClN3O/c1-21-19-24-9-5-6-10-26(24)32(21)27(33)20-30-15-17-31(18-16-30)28(22-7-3-2-4-8-22)23-11-13-25(29)14-12-23/h2-14,21,28H,15-20H2,1H3 SUUFLJYOAPRJGV-UHFFFAOYSA-N 50119963 2-{4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104299 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119963&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335945 104013090 CHEMBL104299 ZINC22941408 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217161 CCc1ccc(CN2CCN(CC(=O)N3C(C)Cc4ccccc34)CC2)cc1 InChI=1S/C24H31N3O/c1-3-20-8-10-21(11-9-20)17-25-12-14-26(15-13-25)18-24(28)27-19(2)16-22-6-4-5-7-23(22)27/h4-11,19H,3,12-18H2,1-2H3 YIILQFFSXRRLJQ-UHFFFAOYSA-N 50119925 2-[4-(4-Ethyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL321538 D(2) dopamine receptor Homo sapiens 753 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119925&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335923 104013052 CHEMBL321538 ZINC22941424 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217162 Clc1ccc(CN2CCN(CCN3C(=O)C(=O)c4ccccc34)CC2)cc1 InChI=1S/C21H22ClN3O2/c22-17-7-5-16(6-8-17)15-24-11-9-23(10-12-24)13-14-25-19-4-2-1-3-18(19)20(26)21(25)27/h1-8H,9-15H2 GWUIEAHZLVKSHB-UHFFFAOYSA-N 50119930 1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-ethyl}-1H-indole-2,3-dione::CHEMBL322567 D(2) dopamine receptor Homo sapiens 1225 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23363843 104013057 CHEMBL322567 ZINC22941362 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217164 CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H27ClN2O/c1-17-14-20-4-2-3-5-22(20)26(17)23(27)15-18-10-12-25(13-11-18)16-19-6-8-21(24)9-7-19/h2-9,17-18H,10-16H2,1H3 JKBANFCMSOHIAB-UHFFFAOYSA-N 50119926 2-[1-(4-Chloro-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104788 D(2) dopamine receptor Homo sapiens 92 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9800164 104013053 CHEMBL104788 ZINC13860111 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217165 CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2cc(C)ccc2C)CC1 InChI=1S/C24H31N3O/c1-18-8-9-19(2)22(14-18)16-25-10-12-26(13-11-25)17-24(28)27-20(3)15-21-6-4-5-7-23(21)27/h4-9,14,20H,10-13,15-17H2,1-3H3 GAZDGUQLDXYUCF-UHFFFAOYSA-N 50119924 2-[4-(2,5-Dimethyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105304 D(2) dopamine receptor Homo sapiens 119 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335876 104013051 CHEMBL105304 ZINC22941483 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217170 CC1CC(C)(C)N(C(=O)CN2CCN(Cc3ccc(Cl)cc3)CC2)c2cc(C)ccc12 InChI=1S/C26H34ClN3O/c1-19-5-10-23-20(2)16-26(3,4)30(24(23)15-19)25(31)18-29-13-11-28(12-14-29)17-21-6-8-22(27)9-7-21/h5-10,15,20H,11-14,16-18H2,1-4H3 JIQPCUQFYHDNJZ-UHFFFAOYSA-N 50119900 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,2,4,7-tetramethyl-3,4-dihydro-2H-quinolin-1-yl)-ethanone::CHEMBL107338 D(2) dopamine receptor Homo sapiens 1926 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119900&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336004 104013027 CHEMBL107338 ZINC22941339 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217178 Cc1cccc2CCN(C(=O)CN3CCN(Cc4ccc(Cl)cc4)CC3)c12 InChI=1S/C22H26ClN3O/c1-17-3-2-4-19-9-10-26(22(17)19)21(27)16-25-13-11-24(12-14-25)15-18-5-7-20(23)8-6-18/h2-8H,9-16H2,1H3 COJAZIUIZFFLJD-UHFFFAOYSA-N 50119893 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(7-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107229 D(2) dopamine receptor Homo sapiens 4623.0 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119893&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886340 104013020 CHEMBL107229 ZINC22941247 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217179 Clc1ccc(CN2CCN(CC(=O)N3c4ccccc4CC33CCCCC3)CC2)cc1 InChI=1S/C26H32ClN3O/c27-23-10-8-21(9-11-23)19-28-14-16-29(17-15-28)20-25(31)30-24-7-3-2-6-22(24)18-26(30)12-4-1-5-13-26/h2-3,6-11H,1,4-5,12-20H2 BXKFWSCAQBNCQC-UHFFFAOYSA-N 50119961 2-[4-(4-chlorobenzyl)hexahydro-1-pyrazinyl]-1-spiro[cyclohexane-1,2'-(2',3'-dihydro-1'H-indole)]-1-yl-1-ethanone::CHEMBL107962 D(2) dopamine receptor Homo sapiens 3325 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336057 104013088 CHEMBL107962 ZINC22941300 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217180 Clc1ccc(CN2CCN(CCCN3c4ccccc4CS3(=O)=O)CC2)cc1 InChI=1S/C21H26ClN3O2S/c22-20-8-6-18(7-9-20)16-24-14-12-23(13-15-24)10-3-11-25-21-5-2-1-4-19(21)17-28(25,26)27/h1-2,4-9H,3,10-17H2 AYLLMRKBBYQUGB-UHFFFAOYSA-N 50119933 1-{3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-propyl}-1,3-dihydro-benzo[c]isothiazole 2,2-dioxide::CHEMBL104380 D(2) dopamine receptor Homo sapiens 979 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119933&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336138 104013060 CHEMBL104380 ZINC22812793 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217182 C[C@@H]1[C@@H](C)c2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H28ClN3O/c1-17-18(2)27(22-6-4-3-5-21(17)22)23(28)16-26-13-11-25(12-14-26)15-19-7-9-20(24)10-8-19/h3-10,17-18H,11-16H2,1-2H3/t17-,18-/m1/s1 PASKDVYJTCOFHQ-QZTJIDSGSA-N 50119942 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-((2R,3S)-2,3-dimethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL319927 D(2) dopamine receptor Homo sapiens 183 ChEMBL 10.1016/s0960-894x(02)00655-8 10.7270/Q2JM2908 12372512 Zhao, H; Thurkauf, A; He, X; Hodgetts, K; Zhang, X; Rachwal, S; Kover, RX; Hutchison, A; Peterson, J; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22953120 104013069 CHEMBL319927 ZINC22941306 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217185 C[C@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O/c1-17-14-19-4-2-3-5-21(19)26(17)22(27)16-25-12-10-24(11-13-25)15-18-6-8-20(23)9-7-18/h2-9,17H,10-16H2,1H3/t17-/m0/s1 JIFUZIJTCAAWNY-KRWDZBQOSA-N 50119966 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-((S)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106119 D(2) dopamine receptor Homo sapiens 9395 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336062 104013093 CHEMBL106119 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217188 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2cc(Cl)ccc2Cl)CC1 InChI=1S/C22H25Cl2N3O/c1-16-12-17-4-2-3-5-21(17)27(16)22(28)15-26-10-8-25(9-11-26)14-18-13-19(23)6-7-20(18)24/h2-7,13,16H,8-12,14-15H2,1H3/t16-/m1/s1 HGHMYQHNOCBXIF-MRXNPFEDSA-N 50119967 2-[4-(2,5-Dichloro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105172 D(2) dopamine receptor Homo sapiens 95 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335973 104013094 CHEMBL105172 ZINC22941500 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217193 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2cccc(Cl)c2)CC1 InChI=1S/C22H26ClN3O/c1-17-13-19-6-2-3-8-21(19)26(17)22(27)16-25-11-9-24(10-12-25)15-18-5-4-7-20(23)14-18/h2-8,14,17H,9-13,15-16H2,1H3/t17-/m1/s1 YWFAGVAANFJWKQ-QGZVFWFLSA-N 50119971 2-[4-(3-Chloro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL321698 D(2) dopamine receptor Homo sapiens 747 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119971&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336012 104013098 CHEMBL321698 ZINC22941486 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217194 CCOc1ccc(Cl)cc1CN1CCN(CC(=O)N2[C@H](C)Cc3ccccc23)CC1 InChI=1S/C24H30ClN3O2/c1-3-30-23-9-8-21(25)15-20(23)16-26-10-12-27(13-11-26)17-24(29)28-18(2)14-19-6-4-5-7-22(19)28/h4-9,15,18H,3,10-14,16-17H2,1-2H3/t18-/m1/s1 QSFIOZUTOJIBTH-GOSISDBHSA-N 50119972 2-[4-(5-Chloro-2-ethoxy-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL326863 D(2) dopamine receptor Homo sapiens 134 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119972&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335909 104013099 CHEMBL326863 ZINC22941507 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217196 COc1cc(Cl)ccc1CN1CCN(CC(=O)N2[C@H](C)Cc3ccccc23)CC1 InChI=1S/C23H28ClN3O2/c1-17-13-18-5-3-4-6-21(18)27(17)23(28)16-26-11-9-25(10-12-26)15-19-7-8-20(24)14-22(19)29-2/h3-8,14,17H,9-13,15-16H2,1-2H3/t17-/m1/s1 HMRRDGDXTNUCPS-QGZVFWFLSA-N 50119974 2-[4-(4-Chloro-2-methoxy-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106862 D(2) dopamine receptor Homo sapiens 273 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119974&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001810 104013101 CHEMBL106862 ZINC22941498 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217205 C[C@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 InChI=1S/C23H29N3O/c1-18-7-9-20(10-8-18)16-24-11-13-25(14-12-24)17-23(27)26-19(2)15-21-5-3-4-6-22(21)26/h3-10,19H,11-17H2,1-2H3/t19-/m0/s1 BKDQVRCFIJMWOR-IBGZPJMESA-N 50119978 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-((S)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105354 D(2) dopamine receptor Homo sapiens 2364 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119978&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335847 104013105 CHEMBL105354 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217212 COc1ccc(CN2CCN(CC(=O)N3[C@H](C)Cc4ccccc34)CC2)cc1 InChI=1S/C23H29N3O2/c1-18-15-20-5-3-4-6-22(20)26(18)23(27)17-25-13-11-24(12-14-25)16-19-7-9-21(28-2)10-8-19/h3-10,18H,11-17H2,1-2H3/t18-/m1/s1 DSNCXRXGMZSRBV-GOSISDBHSA-N 50119984 2-[4-(4-Methoxy-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105317 D(2) dopamine receptor Homo sapiens 673 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119984&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9129986 104013111 CHEMBL105317 ZINC22808908 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217213 CC(C)c1ccc(Cl)cc1CN1CCN(CC(=O)N2[C@H](C)Cc3ccccc23)CC1 InChI=1S/C25H32ClN3O/c1-18(2)23-9-8-22(26)15-21(23)16-27-10-12-28(13-11-27)17-25(30)29-19(3)14-20-6-4-5-7-24(20)29/h4-9,15,18-19H,10-14,16-17H2,1-3H3/t19-/m1/s1 RLNVMGFHVCHHTP-LJQANCHMSA-N 50119983 2-[4-(5-Chloro-2-isopropyl-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL108011 D(2) dopamine receptor Homo sapiens 218 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119983&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335908 104013110 CHEMBL108011 ZINC22941510 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217215 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccccc2Cl)CC1 InChI=1S/C22H26ClN3O/c1-17-14-18-6-3-5-9-21(18)26(17)22(27)16-25-12-10-24(11-13-25)15-19-7-2-4-8-20(19)23/h2-9,17H,10-16H2,1H3/t17-/m1/s1 IEICVHLYUUMYCM-QGZVFWFLSA-N 50119980 2-[4-(2-Chloro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL321201 D(2) dopamine receptor Homo sapiens 1149 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119980&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336000 104013107 CHEMBL321201 ZINC22941492 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217216 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2cc(Cl)cc(Cl)c2)CC1 InChI=1S/C22H25Cl2N3O/c1-16-10-18-4-2-3-5-21(18)27(16)22(28)15-26-8-6-25(7-9-26)14-17-11-19(23)13-20(24)12-17/h2-5,11-13,16H,6-10,14-15H2,1H3/t16-/m1/s1 XKSRPDXBGYGWEX-MRXNPFEDSA-N 50119965 2-[4-(3,5-Dichloro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL326010 D(2) dopamine receptor Homo sapiens 271 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336099 104013092 CHEMBL326010 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217218 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 138 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217221 COc1ccc(OC)c(CN2CCN(CC(=O)N3[C@H](C)Cc4ccccc34)CC2)c1 InChI=1S/C24H31N3O3/c1-18-14-19-6-4-5-7-22(19)27(18)24(28)17-26-12-10-25(11-13-26)16-20-15-21(29-2)8-9-23(20)30-3/h4-9,15,18H,10-14,16-17H2,1-3H3/t18-/m1/s1 CNSLJGGREUXDPB-GOSISDBHSA-N 50119988 2-[4-(2,5-Dimethoxy-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL319043 D(2) dopamine receptor Homo sapiens 59 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119988&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 30740059 104013115 CHEMBL319043 ZINC22933917 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217225 OC(=O)[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H24ClN3O3/c23-18-7-5-16(6-8-18)14-24-9-11-25(12-10-24)15-21(27)26-19-4-2-1-3-17(19)13-20(26)22(28)29/h1-8,20H,9-15H2,(H,28,29)/t20-/m0/s1 PJDHKNHRODMMJT-FQEVSTJZSA-N 50119982 (S)-1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-acetyl}-2,3-dihydro-1H-indole-2-carboxylic acid::CHEMBL106827 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119982&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9931571 104013109 CHEMBL106827 ZINC22941529 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217228 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 InChI=1S/C23H29N3O/c1-18-7-9-20(10-8-18)16-24-11-13-25(14-12-24)17-23(27)26-19(2)15-21-5-3-4-6-22(21)26/h3-10,19H,11-17H2,1-2H3/t19-/m1/s1 BKDQVRCFIJMWOR-LJQANCHMSA-N 50119970 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL320597 D(2) dopamine receptor Homo sapiens 113 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336061 104013097 CHEMBL320597 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217229 CC[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H28ClN3O/c1-2-21-15-19-5-3-4-6-22(19)27(21)23(28)17-26-13-11-25(12-14-26)16-18-7-9-20(24)10-8-18/h3-10,21H,2,11-17H2,1H3/t21-/m1/s1 GGLGRTJZXPCWNM-OAQYLSRUSA-N 50119973 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-((R)-2-ethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL319923 D(2) dopamine receptor Homo sapiens 219 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119973&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335995 104013100 CHEMBL319923 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217230 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(cc2)C(F)(F)F)CC1 InChI=1S/C23H26F3N3O/c1-17-14-19-4-2-3-5-21(19)29(17)22(30)16-28-12-10-27(11-13-28)15-18-6-8-20(9-7-18)23(24,25)26/h2-9,17H,10-16H2,1H3/t17-/m1/s1 MHVPLSWUUSVXMG-QGZVFWFLSA-N 50119987 1-((R)-2-Methyl-2,3-dihydro-indol-1-yl)-2-[4-(4-trifluoromethyl-benzyl)-piperazin-1-yl]-ethanone::CHEMBL105454 D(2) dopamine receptor Homo sapiens 5940 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335835 104013114 CHEMBL105454 ZINC22941438 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217235 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2cc(F)c(Cl)cc2F)CC1 InChI=1S/C22H24ClF2N3O/c1-15-10-16-4-2-3-5-21(16)28(15)22(29)14-27-8-6-26(7-9-27)13-17-11-20(25)18(23)12-19(17)24/h2-5,11-12,15H,6-10,13-14H2,1H3/t15-/m1/s1 KNONQRYHXGQZPG-OAHLLOKOSA-N 50119979 2-[4-(4-Chloro-2,5-difluoro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104323 D(2) dopamine receptor Homo sapiens 2583 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119979&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335877 104013106 CHEMBL104323 ZINC22941518 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217236 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)c(F)c2)CC1 InChI=1S/C23H28FN3O/c1-17-7-8-19(14-21(17)24)15-25-9-11-26(12-10-25)16-23(28)27-18(2)13-20-5-3-4-6-22(20)27/h3-8,14,18H,9-13,15-16H2,1-2H3/t18-/m1/s1 CKZRNAAKFUZSKI-GOSISDBHSA-N 50119985 2-[4-(3-Fluoro-4-methyl-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL317670 D(2) dopamine receptor Homo sapiens 713 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119985&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335889 104013112 CHEMBL317670 ZINC22941521 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217238 CC[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 InChI=1S/C24H31N3O/c1-3-22-16-21-6-4-5-7-23(21)27(22)24(28)18-26-14-12-25(13-15-26)17-20-10-8-19(2)9-11-20/h4-11,22H,3,12-18H2,1-2H3/t22-/m1/s1 LSAYTXKZGVXENK-JOCHJYFZSA-N 50119990 1-((R)-2-Ethyl-2,3-dihydro-indol-1-yl)-2-[4-(4-methyl-benzyl)-piperazin-1-yl]-ethanone::CHEMBL321121 D(2) dopamine receptor Homo sapiens 96 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119990&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335919 104013117 CHEMBL321121 ZINC22941535 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217241 COc1ccc(Cl)cc1CN1CCN(CC(=O)N2[C@H](C)Cc3ccccc23)CC1 InChI=1S/C23H28ClN3O2/c1-17-13-18-5-3-4-6-21(18)27(17)23(28)16-26-11-9-25(10-12-26)15-19-14-20(24)7-8-22(19)29-2/h3-8,14,17H,9-13,15-16H2,1-2H3/t17-/m1/s1 DRZUXCQSFDLIBG-QGZVFWFLSA-N 50119993 2-[4-(5-Chloro-2-methoxy-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104751 D(2) dopamine receptor Homo sapiens 28 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335925 104013120 CHEMBL104751 ZINC22941505 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217242 FC[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H25ClFN3O/c23-19-7-5-17(6-8-19)15-25-9-11-26(12-10-25)16-22(28)27-20(14-24)13-18-3-1-2-4-21(18)27/h1-8,20H,9-16H2/t20-/m0/s1 PGKVYLZMGOBDOJ-FQEVSTJZSA-N 50119969 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-((S)-2-fluoromethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL320721 D(2) dopamine receptor Homo sapiens 1096 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119969&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9930934 104013096 CHEMBL320721 ZINC22941527 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217243 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Homo sapiens 1 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217244 CCc1ccc(CN2CCN(CC(=O)N3[C@H](C)Cc4ccccc34)CC2)cc1 InChI=1S/C24H31N3O/c1-3-20-8-10-21(11-9-20)17-25-12-14-26(15-13-25)18-24(28)27-19(2)16-22-6-4-5-7-23(22)27/h4-11,19H,3,12-18H2,1-2H3/t19-/m1/s1 YIILQFFSXRRLJQ-LJQANCHMSA-N 50119968 2-[4-(4-Ethyl-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL106169 D(2) dopamine receptor Homo sapiens 758 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119968&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336030 104013095 CHEMBL106169 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217246 Clc1ccc(CN2CCN(CC(=O)N3[C@@H](Cc4ccccc34)C(=O)NCc3ccccc3)CC2)cc1 InChI=1S/C29H31ClN4O2/c30-25-12-10-23(11-13-25)20-32-14-16-33(17-15-32)21-28(35)34-26-9-5-4-8-24(26)18-27(34)29(36)31-19-22-6-2-1-3-7-22/h1-13,27H,14-21H2,(H,31,36)/t27-/m0/s1 WNYJACXWJDHSMQ-MHZLTWQESA-N 50119981 (S)-1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-acetyl}-2,3-dihydro-1H-indole-2-carboxylic acid benzylamide::CHEMBL107678 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119981&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9848933 104013108 CHEMBL107678 ZINC22941532 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217257 OC[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O2/c23-19-7-5-17(6-8-19)14-24-9-11-25(12-10-24)15-22(28)26-20(16-27)13-18-3-1-2-4-21(18)26/h1-8,20,27H,9-16H2/t20-/m0/s1 XPXUMEWYIRREDK-FQEVSTJZSA-N 50119989 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-((S)-2-hydroxymethyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107151 D(2) dopamine receptor Homo sapiens 3027 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119989&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9801098 104013116 CHEMBL107151 ZINC22941524 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217259 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(F)c(F)c2Cl)CC1 InChI=1S/C22H24ClF2N3O/c1-15-12-16-4-2-3-5-19(16)28(15)20(29)14-27-10-8-26(9-11-27)13-17-6-7-18(24)22(25)21(17)23/h2-7,15H,8-14H2,1H3/t15-/m1/s1 FFNAGYPIICWACI-OAHLLOKOSA-N 50119994 2-[4-(2-Chloro-3,4-difluoro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL320515 D(2) dopamine receptor Homo sapiens 199 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335893 104013121 CHEMBL320515 ZINC22941515 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217263 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O/c1-17-14-19-4-2-3-5-21(19)26(17)22(27)16-25-12-10-24(11-13-25)15-18-6-8-20(23)9-7-18/h2-9,17H,10-16H2,1H3/t17-/m1/s1 JIFUZIJTCAAWNY-QGZVFWFLSA-N 50119964 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL108282 D(2) dopamine receptor Homo sapiens 191 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335960 104013091 CHEMBL108282 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217270 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccccc2F)CC1 InChI=1S/C22H26FN3O/c1-17-14-18-6-3-5-9-21(18)26(17)22(27)16-25-12-10-24(11-13-25)15-19-7-2-4-8-20(19)23/h2-9,17H,10-16H2,1H3/t17-/m1/s1 QVQNYZMNWDLQTI-QGZVFWFLSA-N 50119996 2-[4-(2-Fluoro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL110712 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336313 104013123 CHEMBL110712 ZINC22941495 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217273 Clc1ccc(CN2CCN(CC(=O)N3[C@@H](Cc4ccccc34)C=C)CC2)cc1 InChI=1S/C23H26ClN3O/c1-2-21-15-19-5-3-4-6-22(19)27(21)23(28)17-26-13-11-25(12-14-26)16-18-7-9-20(24)10-8-18/h2-10,21H,1,11-17H2/t21-/m1/s1 UIRKAHAECJAUIH-OAQYLSRUSA-N 50119977 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-((S)-2-vinyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL431640 D(2) dopamine receptor Homo sapiens 271 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119977&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865490 104013104 CHEMBL431640 ZINC22454065 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217274 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(F)cc2)CC1 InChI=1S/C22H26FN3O/c1-17-14-19-4-2-3-5-21(19)26(17)22(27)16-25-12-10-24(11-13-25)15-18-6-8-20(23)9-7-18/h2-9,17H,10-16H2,1H3/t17-/m1/s1 MKNRXBPDERAOEB-QGZVFWFLSA-N 50119992 2-[4-(4-Fluoro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104058 D(2) dopamine receptor Homo sapiens 286 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119992&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336047 104013119 CHEMBL104058 ZINC22941410 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217276 COC(=O)[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C23H26ClN3O3/c1-30-23(29)21-14-18-4-2-3-5-20(18)27(21)22(28)16-26-12-10-25(11-13-26)15-17-6-8-19(24)9-7-17/h2-9,21H,10-16H2,1H3/t21-/m0/s1 FZEKBTQTBQVMTK-NRFANRHFSA-N 50119976 (S)-1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-acetyl}-2,3-dihydro-1H-indole-2-carboxylic acid methyl ester::CHEMBL107631 D(2) dopamine receptor Homo sapiens 1178 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119976&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9867233 104013103 CHEMBL107631 ZINC22454056 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217279 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2cccc(F)c2)CC1 InChI=1S/C22H26FN3O/c1-17-13-19-6-2-3-8-21(19)26(17)22(27)16-25-11-9-24(10-12-25)15-18-5-4-7-20(23)14-18/h2-8,14,17H,9-13,15-16H2,1H3/t17-/m1/s1 IFIIHJSXBMXLER-QGZVFWFLSA-N 50119975 2-[4-(3-Fluoro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105601 D(2) dopamine receptor Homo sapiens 1000 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119975&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336027 104013102 CHEMBL105601 ZINC22941489 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217280 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc3OCOc3c2)CC1 InChI=1S/C23H27N3O3/c1-17-12-19-4-2-3-5-20(19)26(17)23(27)15-25-10-8-24(9-11-25)14-18-6-7-21-22(13-18)29-16-28-21/h2-7,13,17H,8-12,14-16H2,1H3/t17-/m1/s1 WNIDJZPMTZKYGD-QGZVFWFLSA-N 50119991 2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL322222 D(2) dopamine receptor Homo sapiens 1434 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1946142 104013118 CHEMBL322222 ZINC19899639 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217283 COC(=O)[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 InChI=1S/C24H29N3O3/c1-18-7-9-19(10-8-18)16-25-11-13-26(14-12-25)17-23(28)27-21-6-4-3-5-20(21)15-22(27)24(29)30-2/h3-10,22H,11-17H2,1-2H3/t22-/m0/s1 UXFGATIIHSOJJZ-QFIPXVFZSA-N 50119986 (S)-1-{2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-acetyl}-2,3-dihydro-1H-indole-2-carboxylic acid methyl ester::CHEMBL105745 D(2) dopamine receptor Homo sapiens 491 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119986&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335918 104013113 CHEMBL105745 ZINC22941538 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50217284 C[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C22H25Cl2N3O/c1-16-12-18-4-2-3-5-21(18)27(16)22(28)15-26-10-8-25(9-11-26)14-17-6-7-19(23)20(24)13-17/h2-7,13,16H,8-12,14-15H2,1H3/t16-/m1/s1 WVYXCJHHNDTVPH-MRXNPFEDSA-N 50119995 2-[4-(3,4-Dichloro-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL104678 D(2) dopamine receptor Homo sapiens 43 ChEMBL 10.1016/s0960-894x(02)00656-x 10.7270/Q2DZ07ND 12372513 Zhao, H; He, X; Thurkauf, A; Hoffman, D; Kieltyka, A; Brodbeck, R; Primus, R; Wasley, JW Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335996 104013122 CHEMBL104678 ZINC22941503 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226182 COc1ccccc1N1CCN(Cc2cn(CCOCCF)nn2)CC1 InChI=1S/C18H26FN5O2/c1-25-18-5-3-2-4-17(18)23-9-7-22(8-10-23)14-16-15-24(21-20-16)11-13-26-12-6-19/h2-5,15H,6-14H2,1H3 FLNGBOIVGQBOBU-UHFFFAOYSA-N 50442746 CHEMBL2443010 D(2) dopamine receptor Homo sapiens 750 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442746&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72544789 175455063 CHEMBL2443010 ZINC96286416 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226188 COc1ccccc1N1CCN(Cc2cn(CCCCCCF)nn2)CC1 InChI=1S/C20H30FN5O/c1-27-20-9-5-4-8-19(20)25-14-12-24(13-15-25)16-18-17-26(23-22-18)11-7-3-2-6-10-21/h4-5,8-9,17H,2-3,6-7,10-16H2,1H3 UQNPMHBOQOCPSK-UHFFFAOYSA-N 50442747 CHEMBL2443009 D(2) dopamine receptor Homo sapiens 560 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442747&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72544566 175455064 CHEMBL2443009 ZINC96286417 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226194 COc1ccccc1N1CCN(Cc2cn(nn2)-c2ccc(OCCCOCCF)cc2)CC1 InChI=1S/C25H32FN5O3/c1-32-25-6-3-2-5-24(25)30-14-12-29(13-15-30)19-21-20-31(28-27-21)22-7-9-23(10-8-22)34-17-4-16-33-18-11-26/h2-3,5-10,20H,4,11-19H2,1H3 GVZVJCKGJVWISH-UHFFFAOYSA-N 50442749 CHEMBL2443007 D(2) dopamine receptor Homo sapiens 770 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442749&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72545240 175455066 CHEMBL2443007 ZINC96286420 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226197 COc1ccccc1N1CCN(Cc2cn(nn2)-c2ccc(OCCCOC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3F)cc2)CC1 InChI=1S/C29H38FN5O7/c1-39-24-6-3-2-5-23(24)34-13-11-33(12-14-34)17-20-18-35(32-31-20)21-7-9-22(10-8-21)40-15-4-16-41-29-26(30)28(38)27(37)25(19-36)42-29/h2-3,5-10,18,25-29,36-38H,4,11-17,19H2,1H3/t25-,26-,27-,28-,29?/m1/s1 UYUTUOIZGIGQQA-VIVFLBMVSA-N 50442748 CHEMBL2443008 D(2) dopamine receptor Homo sapiens 1500 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442748&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72544787 175455065 CHEMBL2443008 ZINC96286419 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226209 COc1ccccc1N1CCN(Cc2cn(CCOCCOCCOCCF)nn2)CC1 InChI=1S/C22H34FN5O4/c1-29-22-5-3-2-4-21(22)27-9-7-26(8-10-27)18-20-19-28(25-24-20)11-13-31-15-17-32-16-14-30-12-6-23/h2-5,19H,6-18H2,1H3 WTAVHOMZPZTGNJ-UHFFFAOYSA-N 50442755 CHEMBL2443001 D(2) dopamine receptor Homo sapiens 4700 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72545008 175455072 CHEMBL2443001 ZINC96286426 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226214 COc1ccccc1N1CCN(Cc2cn(nn2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2F)CC1 InChI=1S/C20H28FN5O5/c1-30-15-5-3-2-4-14(15)25-8-6-24(7-9-25)10-13-11-26(23-22-13)20-17(21)19(29)18(28)16(12-27)31-20/h2-5,11,16-20,27-29H,6-10,12H2,1H3/t16-,17-,18-,19-,20-/m1/s1 SSVIIFPCYYWMIA-LASHMREHSA-N 50442754 CHEMBL2443002 D(2) dopamine receptor Homo sapiens 42000 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442754&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72545009 175455071 CHEMBL2443002 ZINC96286425 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226222 COc1ccccc1N1CCN(Cc2cn(nn2)-c2ccccc2)CC1 InChI=1S/C20H23N5O/c1-26-20-10-6-5-9-19(20)24-13-11-23(12-14-24)15-17-16-25(22-21-17)18-7-3-2-4-8-18/h2-10,16H,11-15H2,1H3 PDQWDSWLQAHIBM-UHFFFAOYSA-N 50184805 1-(2-methoxyphenyl)-4-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)piperazine::CHEMBL210232 D(2) dopamine receptor Homo sapiens 65 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44412269 104069122 CHEMBL210232 ZINC36216625 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226223 COc1ccccc1N1CCN(Cc2cn(CCOCCOCCF)nn2)CC1 InChI=1S/C20H30FN5O3/c1-27-20-5-3-2-4-19(20)25-9-7-24(8-10-25)16-18-17-26(23-22-18)11-13-29-15-14-28-12-6-21/h2-5,17H,6-16H2,1H3 BGXXETBYBGTKEP-UHFFFAOYSA-N 50442756 CHEMBL2443000 D(2) dopamine receptor Homo sapiens 3400 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72545007 175455073 CHEMBL2443000 ZINC96286427 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226227 COc1ccccc1N1CCN(Cc2cn(nn2)-c2ccc(OCCCF)cc2)CC1 InChI=1S/C23H28FN5O2/c1-30-23-6-3-2-5-22(23)28-14-12-27(13-15-28)17-19-18-29(26-25-19)20-7-9-21(10-8-20)31-16-4-11-24/h2-3,5-10,18H,4,11-17H2,1H3 XUOARYPFOGJNNV-UHFFFAOYSA-N 50442751 CHEMBL2443005 D(2) dopamine receptor Homo sapiens 520 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442751&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72545238 175455068 CHEMBL2443005 ZINC96286422 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226231 COc1ccccc1N1CCN(Cc2cn(nn2)-c2ccc(OCCOCCOCCF)cc2)CC1 InChI=1S/C26H34FN5O4/c1-33-26-5-3-2-4-25(26)31-13-11-30(12-14-31)20-22-21-32(29-28-22)23-6-8-24(9-7-23)36-19-18-35-17-16-34-15-10-27/h2-9,21H,10-20H2,1H3 NJTHDWRTKWUXOY-UHFFFAOYSA-N 50442750 CHEMBL2443006 D(2) dopamine receptor Homo sapiens 2900 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442750&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72545239 175455067 CHEMBL2443006 ZINC96286421 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226238 COc1ccccc1N1CCN(Cc2cn(nn2)[C@@H]2O[C@H](CF)[C@@H](O)[C@H](O)[C@H]2O)CC1 InChI=1S/C20H28FN5O5/c1-30-15-5-3-2-4-14(15)25-8-6-24(7-9-25)11-13-12-26(23-22-13)20-19(29)18(28)17(27)16(10-21)31-20/h2-5,12,16-20,27-29H,6-11H2,1H3/t16-,17-,18+,19-,20-/m1/s1 WHDATORJGMRETC-OUUBHVDSSA-N 50442753 CHEMBL2443003 D(2) dopamine receptor Homo sapiens 51000 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442753&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72545010 175455070 CHEMBL2443003 ZINC96286424 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226239 COc1ccccc1N1CCN(Cc2cn(nn2)-c2ccc(OCCF)cc2)CC1 InChI=1S/C22H26FN5O2/c1-29-22-5-3-2-4-21(22)27-13-11-26(12-14-27)16-18-17-28(25-24-18)19-6-8-20(9-7-19)30-15-10-23/h2-9,17H,10-16H2,1H3 LHYAIPJNIYZFAE-UHFFFAOYSA-N 50442752 CHEMBL2443004 D(2) dopamine receptor Homo sapiens 18000 ChEMBL 10.1016/j.bmcl.2013.09.026 10.7270/Q2028T08 24100078 Banerjee, A; Maschauer, S; Hubner, H; Gmeiner, P; Prante, O Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442752&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72545011 175455069 CHEMBL2443004 ZINC96286423 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50224035 Oc1ccccc1C(=O)CCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C23H27N3O3/c27-20(18-8-3-5-11-21(18)28)10-2-1-7-13-25-14-16-26(17-15-25)23-19-9-4-6-12-22(19)29-24-23/h3-6,8-9,11-12,28H,1-2,7,10,13-17H2 BWXABDUNWUIBLQ-UHFFFAOYSA-N 50123697 6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hydroxy-phenyl)-hexan-1-one::CHEMBL160817 D(2) dopamine receptor Homo sapiens 246 ChEMBL 10.1021/jm020994z 10.7270/Q23T9GKN 12570387 Perrone, R; Berardi, F; Colabufo, NA; Lacivita, E; Leopoldo, M; Tortorella, V Università degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430685 104016109 CHEMBL160817 ZINC13493254 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50224041 COc1ccccc1C(=O)CCCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C24H29N3O3/c1-29-22-12-6-4-9-19(22)21(28)11-3-2-8-14-26-15-17-27(18-16-26)24-20-10-5-7-13-23(20)30-25-24/h4-7,9-10,12-13H,2-3,8,11,14-18H2,1H3 VRSNKCQWIMHWFX-UHFFFAOYSA-N 50123695 6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-methoxy-phenyl)-hexan-1-one::CHEMBL159022 D(2) dopamine receptor Homo sapiens 78.1 ChEMBL 10.1021/jm020994z 10.7270/Q23T9GKN 12570387 Perrone, R; Berardi, F; Colabufo, NA; Lacivita, E; Leopoldo, M; Tortorella, V Università degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123695&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10069973 104016107 CHEMBL159022 ZINC13493257 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50223028 COc1ccccc1CNCc1cccc(CCNC[C@H](O)c2ccc(O)c3[nH]c(=O)sc23)c1 InChI=1S/C26H29N3O4S/c1-33-23-8-3-2-7-19(23)15-28-14-18-6-4-5-17(13-18)11-12-27-16-22(31)20-9-10-21(30)24-25(20)34-26(32)29-24/h2-10,13,22,27-28,30-31H,11-12,14-16H2,1H3,(H,29,32)/t22-/m0/s1 VKCKAMBPNXKGHL-QFIPXVFZSA-N 50419680 CHEMBL1945039 D(2) dopamine receptor Homo sapiens 251 ChEMBL 10.1016/j.bmcl.2011.10.049 10.7270/Q2KW5H90 22079756 Alcaraz, L; Bailey, A; Cadogan, E; Connolly, S; Jewell, R; Jordan, S; Kindon, N; Lister, A; Lawson, M; Mullen, A; Dainty, I; Nicholls, D; Paine, S; Pairaudeau, G; Stocks, MJ; Thorne, P; Young, A AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24900689 163368704 CHEMBL1945039 ZINC59083343 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226405 Clc1ccc(CN2CCN(CC2)C2CCc3cccc4CCN(c34)C2=O)cc1 InChI=1S/C23H26ClN3O/c24-20-7-4-17(5-8-20)16-25-12-14-26(15-13-25)21-9-6-18-2-1-3-19-10-11-27(22(18)19)23(21)28/h1-5,7-8,21H,6,9-16H2 MDCLDPYRUQCBTL-UHFFFAOYSA-N 50124931 5-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL352207 D(2) dopamine receptor Homo sapiens 62 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124931&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10157556 104017181 CHEMBL352207 ZINC22927099 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226408 CCN1C(=O)C(Cc2ccccc12)N1CCN(Cc2ccc(Cl)cc2)CC1 InChI=1S/C22H26ClN3O/c1-2-26-20-6-4-3-5-18(20)15-21(22(26)27)25-13-11-24(12-14-25)16-17-7-9-19(23)10-8-17/h3-10,21H,2,11-16H2,1H3 BZWQAKCTTBOIKJ-UHFFFAOYSA-N 50092046 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-ethyl-3,4-dihydro-1H-quinolin-2-one::CHEMBL68191 D(2) dopamine receptor Homo sapiens 21 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10045525 103990258 CHEMBL68191 ZINC22927084 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226413 CC1Cc2cccc3CCC(N4CCN(Cc5ccc(C)cc5)CC4)C(=O)N1c23 InChI=1S/C25H31N3O/c1-18-6-8-20(9-7-18)17-26-12-14-27(15-13-26)23-11-10-21-4-3-5-22-16-19(2)28(24(21)22)25(23)29/h3-9,19,23H,10-17H2,1-2H3 DKBPJHJAUABOCD-UHFFFAOYSA-N 50124935 2-Methyl-5-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL345438 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44374827 104017185 CHEMBL345438 ZINC22927128 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226415 Clc1ccc(CN2CCN(CC(=O)N3CCc4ccccc34)CC2)cc1 InChI=1S/C21H24ClN3O/c22-19-7-5-17(6-8-19)15-23-11-13-24(14-12-23)16-21(26)25-10-9-18-3-1-2-4-20(18)25/h1-8H,9-16H2 UHEJJZNLPMHGJA-UHFFFAOYSA-N 50092053 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-ethanone::CHEMBL69584 D(2) dopamine receptor Homo sapiens 690 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9104271 103990265 CHEMBL69584 ZINC21763183 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226417 Cc1ccc(CN2CCN(CC2)C2CCc3cccc4CC(C)(C)N(c34)C2=O)cc1 InChI=1S/C26H33N3O/c1-19-7-9-20(10-8-19)18-27-13-15-28(16-14-27)23-12-11-21-5-4-6-22-17-26(2,3)29(24(21)22)25(23)30/h4-10,23H,11-18H2,1-3H3 OLGSDKVBQGETRV-UHFFFAOYSA-N 50124936 2,2-Dimethyl-5-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL351989 D(2) dopamine receptor Homo sapiens 165 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124936&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44374863 104017186 CHEMBL351989 ZINC22927140 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226420 CC1(C)Cc2cccc3CCC(N4CCN(Cc5ccc(Cl)cc5)CC4)C(=O)N1c23 InChI=1S/C25H30ClN3O/c1-25(2)16-20-5-3-4-19-8-11-22(24(30)29(25)23(19)20)28-14-12-27(13-15-28)17-18-6-9-21(26)10-7-18/h3-7,9-10,22H,8,11-17H2,1-2H3 INLLPBCEAMPLDT-UHFFFAOYSA-N 50124937 5-[4-(4-Chloro-benzyl)-piperazin-1-yl]-2,2-dimethyl-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL439646 D(2) dopamine receptor Homo sapiens 201 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124937&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10224165 104017187 CHEMBL439646 ZINC22927132 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226422 COc1ccc(Cl)cc1CN1CCN(CC1)C1CCc2cccc3CC(C)(C)N(c23)C1=O InChI=1S/C26H32ClN3O2/c1-26(2)16-19-6-4-5-18-7-9-22(25(31)30(26)24(18)19)29-13-11-28(12-14-29)17-20-15-21(27)8-10-23(20)32-3/h4-6,8,10,15,22H,7,9,11-14,16-17H2,1-3H3 BTFSLEXEAAFSHO-UHFFFAOYSA-N 50124938 5-[4-(5-Chloro-2-methoxy-benzyl)-piperazin-1-yl]-2,2-dimethyl-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL354699 D(2) dopamine receptor Homo sapiens 220 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10115074 104017188 CHEMBL354699 ZINC22927161 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226423 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Homo sapiens 113 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226427 Cc1ccc(CN2CCN(CC2)C2CCc3cccc4CCN(c34)C2=O)cc1 InChI=1S/C24H29N3O/c1-18-5-7-19(8-6-18)17-25-13-15-26(16-14-25)22-10-9-20-3-2-4-21-11-12-27(23(20)21)24(22)28/h2-8,22H,9-17H2,1H3 VKKGUQYWMBPDPR-UHFFFAOYSA-N 50124932 5-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL351963 D(2) dopamine receptor Homo sapiens 209 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124932&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9799781 104017182 CHEMBL351963 ZINC22927103 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226433 COc1cc(C)ccc1CN1CCN(CC1)C1CCc2cccc3CC(C)(C)N(c23)C1=O InChI=1S/C27H35N3O2/c1-19-8-9-22(24(16-19)32-4)18-28-12-14-29(15-13-28)23-11-10-20-6-5-7-21-17-27(2,3)30(25(20)21)26(23)31/h5-9,16,23H,10-15,17-18H2,1-4H3 PPLIBGVHLPPEBD-UHFFFAOYSA-N 50124933 5-[4-(2-Methoxy-4-methyl-benzyl)-piperazin-1-yl]-2,2-dimethyl-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL159742 D(2) dopamine receptor Homo sapiens 952.0 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124933&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10137748 104017183 CHEMBL159742 ZINC22927148 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226434 COc1ccc(C)cc1CN1CCN(CC1)C1CCc2cccc3CC(C)(C)N(c23)C1=O InChI=1S/C27H35N3O2/c1-19-8-11-24(32-4)22(16-19)18-28-12-14-29(15-13-28)23-10-9-20-6-5-7-21-17-27(2,3)30(25(20)21)26(23)31/h5-8,11,16,23H,9-10,12-15,17-18H2,1-4H3 HBAHXUZJEDMSCG-UHFFFAOYSA-N 50124939 5-[4-(2-Methoxy-5-methyl-benzyl)-piperazin-1-yl]-2,2-dimethyl-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL351612 D(2) dopamine receptor Homo sapiens 313 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10137747 104017189 CHEMBL351612 ZINC22927153 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226435 CCN1c2ccccc2CCC(N2CCN(Cc3ccc(Cl)cc3)CC2)C1=O InChI=1S/C23H28ClN3O/c1-2-27-21-6-4-3-5-19(21)9-12-22(23(27)28)26-15-13-25(14-16-26)17-18-7-10-20(24)11-8-18/h3-8,10-11,22H,2,9,12-17H2,1H3 MXHNYUJDGHIFRV-UHFFFAOYSA-N 50092054 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-ethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL67414 D(2) dopamine receptor Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9930722 103990266 CHEMBL67414 ZINC22927092 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226441 CC1Cc2cccc3CCC(N4CCN(Cc5ccc(Cl)cc5)CC4)C(=O)N1c23 InChI=1S/C24H28ClN3O/c1-17-15-20-4-2-3-19-7-10-22(24(29)28(17)23(19)20)27-13-11-26(12-14-27)16-18-5-8-21(25)9-6-18/h2-6,8-9,17,22H,7,10-16H2,1H3 DGUCYPDNCXXCGB-UHFFFAOYSA-N 50124934 5-[4-(4-Chloro-benzyl)-piperazin-1-yl]-2-methyl-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL349833 D(2) dopamine receptor Homo sapiens 139 ChEMBL 10.1016/s0960-894x(02)01056-9 10.7270/Q2B56J44 12639562 Zhao, H; Zhang, X; Hodgetts, K; Thurkauf, A; Hammer, J; Chandrasekhar, J; Kieltyka, A; Brodbeck, R; Rachwal, S; Primus, R; Manly, C Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10158455 104017184 CHEMBL349833 ZINC22927114 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50214201 O=C(Cc1ccccc1)NC1CCN(CCCN2C(=O)COc3ccccc23)CC1 InChI=1S/C24H29N3O3/c28-23(17-19-7-2-1-3-8-19)25-20-11-15-26(16-12-20)13-6-14-27-21-9-4-5-10-22(21)30-18-24(27)29/h1-5,7-10,20H,6,11-18H2,(H,25,28) FLGSUSWMWSZVMP-UHFFFAOYSA-N 50326218 CHEMBL1242923::N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]-piperidin-4-yl}-2-phenylacetamide D(2) dopamine receptor Homo sapiens <1000 ChEMBL 10.1021/jm100697g 10.7270/Q2765G9K 20684563 Sams, AG; Hentzer, M; Mikkelsen, GK; Larsen, K; Bundgaard, C; Plath, N; Christoffersen, CT; Bang-Andersen, B H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326218&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44207909 123105333 CHEMBL1242923 5435 ZINC64573958 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50214204 CCCCC1CCN(CCCC(=O)c2ccccc2C)CC1 InChI=1S/C20H31NO/c1-3-4-9-18-12-15-21(16-13-18)14-7-11-20(22)19-10-6-5-8-17(19)2/h5-6,8,10,18H,3-4,7,9,11-16H2,1-2H3 ANTKBACNWQHQJE-UHFFFAOYSA-N 50326219 4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one::CHEMBL1242950::CHEMBL2206334 D(2) dopamine receptor Homo sapiens <1000 ChEMBL 10.1021/jm100697g 10.7270/Q2765G9K 20684563 Sams, AG; Hentzer, M; Mikkelsen, GK; Larsen, K; Bundgaard, C; Plath, N; Christoffersen, CT; Bang-Andersen, B H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326219&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948320 123105334 CHEMBL2206334CHEMBL1242950 289 ZINC02022527 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50214210 O=C(Cc1ccccc1)NC1CCN(CCCN2C(=O)COc3ccccc23)CC1 InChI=1S/C24H29N3O3/c28-23(17-19-7-2-1-3-8-19)25-20-11-15-26(16-12-20)13-6-14-27-21-9-4-5-10-22(21)30-18-24(27)29/h1-5,7-10,20H,6,11-18H2,(H,25,28) FLGSUSWMWSZVMP-UHFFFAOYSA-N 50326218 CHEMBL1242923::N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]-piperidin-4-yl}-2-phenylacetamide D(2) dopamine receptor Homo sapiens <1000 ChEMBL 10.1021/jm100697g 10.7270/Q2765G9K 20684563 Sams, AG; Hentzer, M; Mikkelsen, GK; Larsen, K; Bundgaard, C; Plath, N; Christoffersen, CT; Bang-Andersen, B H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326218&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44207909 123105333 CHEMBL1242923 5435 ZINC64573958 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236955 C(Cc1ccccc1)C1CN(Cc2nc3ccccc3[nH]2)CCO1 InChI=1S/C20H23N3O/c1-2-6-16(7-3-1)10-11-17-14-23(12-13-24-17)15-20-21-18-8-4-5-9-19(18)22-20/h1-9,17H,10-15H2,(H,21,22) JVQBISWUXRKBAJ-UHFFFAOYSA-N 50027072 CHEMBL3335535 D(2) dopamine receptor Homo sapiens >100000 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027072&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19964406 103936654 CHEMBL3335535 512 ZINC00001564 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236959 C(Cc1ccccc1)[C@H]1CN(Cc2nc3ccccc3[nH]2)CCO1 50027077 CHEMBL3335536 D(2) dopamine receptor Homo sapiens >100000 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027077&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92640710 313065318 CHEMBL3335536 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236960 C(Cc1ccccc1)[C@@H]1CN(Cc2nc3ccccc3[nH]2)CCO1 InChI=1S/C20H23N3O/c1-2-6-16(7-3-1)10-11-17-14-23(12-13-24-17)15-20-21-18-8-4-5-9-19(18)22-20/h1-9,17H,10-15H2,(H,21,22)/t17-/m1/s1 JVQBISWUXRKBAJ-QGZVFWFLSA-N 50027074 CHEMBL3335537 D(2) dopamine receptor Homo sapiens >100000 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027074&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149678 103936656 CHEMBL3335537 ZINC05161709 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236974 FC(F)(F)Oc1ccc(CN2CCOC(CCc3ccccc3)C2)cc1 InChI=1S/C20H22F3NO2/c21-20(22,23)26-18-9-7-17(8-10-18)14-24-12-13-25-19(15-24)11-6-16-4-2-1-3-5-16/h1-5,7-10,19H,6,11-15H2 RXEIDFSWABFHSZ-UHFFFAOYSA-N 50027078 CHEMBL3335538 D(2) dopamine receptor Homo sapiens 5500 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027078&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72737744 313065319 CHEMBL3335538 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236975 COc1ccc(CN2CCOC(CCc3ccccc3)C2)cc1 InChI=1S/C20H25NO2/c1-22-19-10-8-18(9-11-19)15-21-13-14-23-20(16-21)12-7-17-5-3-2-4-6-17/h2-6,8-11,20H,7,12-16H2,1H3 DFDOLOVKMMATDA-UHFFFAOYSA-N 50027079 CHEMBL3335539 D(2) dopamine receptor Homo sapiens 16500 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027079&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72737728 313065320 CHEMBL3335539 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236976 FC(F)(F)Oc1ccc(CN2CCO[C@H](CCc3ccccc3)C2)cc1 InChI=1S/C20H22F3NO2/c21-20(22,23)26-18-9-7-17(8-10-18)14-24-12-13-25-19(15-24)11-6-16-4-2-1-3-5-16/h1-5,7-10,19H,6,11-15H2/t19-/m1/s1 RXEIDFSWABFHSZ-LJQANCHMSA-N 50027080 CHEMBL3335554 D(2) dopamine receptor Homo sapiens 5500 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027080&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72737730 313065321 CHEMBL3335554 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236977 Oc1ccc(CN2CCO[C@H](CCc3ccccc3)C2)cc1 InChI=1S/C19H23NO2/c21-18-9-6-17(7-10-18)14-20-12-13-22-19(15-20)11-8-16-4-2-1-3-5-16/h1-7,9-10,19,21H,8,11-15H2/t19-/m1/s1 PSDFKKSPYSFZKR-LJQANCHMSA-N 50027081 CHEMBL3335555 D(2) dopamine receptor Homo sapiens 16500 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027081&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118714552 313065322 CHEMBL3335555 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236989 C(Cc1ccccc1)C1CN(Cc2nc3ccccc3[nH]2)CCO1 InChI=1S/C20H23N3O/c1-2-6-16(7-3-1)10-11-17-14-23(12-13-24-17)15-20-21-18-8-4-5-9-19(18)22-20/h1-9,17H,10-15H2,(H,21,22) JVQBISWUXRKBAJ-UHFFFAOYSA-N 50027072 CHEMBL3335535 D(2) dopamine receptor Homo sapiens >100000 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027072&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19964406 103936654 CHEMBL3335535 512 ZINC00001564 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236990 C(Cc1ccccc1)[C@H]1CN(Cc2nc3ccccc3[nH]2)CCO1 50027077 CHEMBL3335536 D(2) dopamine receptor Homo sapiens >100000 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027077&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 92640710 313065318 CHEMBL3335536 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50236991 C(Cc1ccccc1)[C@@H]1CN(Cc2nc3ccccc3[nH]2)CCO1 InChI=1S/C20H23N3O/c1-2-6-16(7-3-1)10-11-17-14-23(12-13-24-17)15-20-21-18-8-4-5-9-19(18)22-20/h1-9,17H,10-15H2,(H,21,22)/t17-/m1/s1 JVQBISWUXRKBAJ-QGZVFWFLSA-N 50027074 CHEMBL3335537 D(2) dopamine receptor Homo sapiens >100000 ChEMBL 10.1021/ml500267c 10.7270/Q2G44RWM 25221667 Berry, CB; Bubser, M; Jones, CK; Hayes, JP; Wepy, JA; Locuson, CW; Daniels, JS; Lindsley, CW; Hopkins, CR Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027074&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149678 103936656 CHEMBL3335537 ZINC05161709 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226795 CCNC(=O)Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C27H33FN4O2S/c1-2-29-27(34)30-22-16-18(28)9-10-20(22)24(33)7-4-12-31-14-11-23-21(17-31)19-6-3-8-25-26(19)32(23)13-5-15-35-25/h3,6,8-10,16,21,23H,2,4-5,7,11-15,17H2,1H3,(H2,29,30,34)/t21-,23-/m0/s1 JSSVAHJXBGMKKR-GMAHTHKFSA-N 50125149 1-Ethyl-3-[5-fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butyryl)-phenyl]-urea::CHEMBL163895 D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125149&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378141 104017383 CHEMBL163895 ZINC13488006 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226800 Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3CCCN2c13 InChI=1S/C24H28FN3O/c25-17-8-9-19(21(26)14-17)23(29)7-3-11-27-13-10-22-20(15-27)18-6-1-4-16-5-2-12-28(22)24(16)18/h1,4,6,8-9,14,20,22H,2-3,5,7,10-13,15,26H2/t20-,22-/m0/s1 HHUBBKQNDFELCT-UNMCSNQZSA-N 50125154 1-(2-Amino-4-fluoro-phenyl)-4-(7aS,11aR)-5,6,8,9,11,11a-hexahydro-4H,7aH-pyrido[3',4':4,5]pyrrolo[3,2,1-ij]quinolin-10-yl-butan-1-one::CHEMBL351592 D(2) dopamine receptor Homo sapiens 5.2 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125154&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378003 104017388 CHEMBL351592 ZINC13488017 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226803 Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3OCCN2c13 InChI=1S/C23H26FN3O2/c24-15-6-7-17(19(25)13-15)21(28)4-2-9-26-10-8-20-18(14-26)16-3-1-5-22-23(16)27(20)11-12-29-22/h1,3,5-7,13,18,20H,2,4,8-12,14,25H2/t18-,20-/m0/s1 LEDYBEGWCAWDCY-ICSRJNTNSA-N 50125155 1-(2-Amino-4-fluoro-phenyl)-4-(6bR,10aS)-1,2,6b,9,10,10a-hexahydro-7H-3-oxa-8,10b-diaza-fluoranthen-8-yl-butan-1-one::CHEMBL165780 D(2) dopamine receptor Homo sapiens 2.3 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125155&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865463 104017389 CHEMBL165780 ZINC01493719 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226810 Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCN2c13 InChI=1S/C23H26FN3OS/c24-15-6-7-17(19(25)13-15)21(28)4-2-9-26-10-8-20-18(14-26)16-3-1-5-22-23(16)27(20)11-12-29-22/h1,3,5-7,13,18,20H,2,4,8-12,14,25H2/t18-,20-/m0/s1 RFRAMVDLVRFQPK-ICSRJNTNSA-N 50125161 1-(2-Amino-4-fluoro-phenyl)-4-(6bR,10aS)-1,2,6b,9,10,10a-hexahydro-7H-3-thia-8,10b-diaza-fluoranthen-8-yl-butan-1-one::CHEMBL354005 D(2) dopamine receptor Homo sapiens 4 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125161&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377927 104017395 CHEMBL354005 ZINC13488011 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226813 Nc1ccccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3CCCCN2c13 InChI=1S/C25H31N3O/c26-22-11-2-1-9-20(22)24(29)12-6-14-27-16-13-23-21(17-27)19-10-5-8-18-7-3-4-15-28(23)25(18)19/h1-2,5,8-11,21,23H,3-4,6-7,12-17,26H2/t21-,23-/m0/s1 IOXYLQYEPCUPNE-GMAHTHKFSA-N 50125163 1-(2-Amino-phenyl)-4-(7bS,11aR)-4,5,6,7,8,9,11,11a-octahydro-7bH-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL352194 D(2) dopamine receptor Homo sapiens 11 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125163&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378381 104017397 CHEMBL352194 ZINC13488020 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226814 CS(=O)(=O)Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C25H30FN3O3S2/c1-34(31,32)27-21-15-17(26)8-9-19(21)23(30)6-3-11-28-13-10-22-20(16-28)18-5-2-7-24-25(18)29(22)12-4-14-33-24/h2,5,7-9,15,20,22,27H,3-4,6,10-14,16H2,1H3/t20-,22-/m0/s1 DJAYOTFCMKFULR-UNMCSNQZSA-N 50125162 CHEMBL162102::N-[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butyryl)-phenyl]-methanesulfonamide D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125162&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377901 104017396 CHEMBL162102 ZINC13488007 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226823 Nc1cc(Br)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H28BrN3OS/c25-16-7-8-18(20(26)14-16)22(29)5-2-10-27-12-9-21-19(15-27)17-4-1-6-23-24(17)28(21)11-3-13-30-23/h1,4,6-8,14,19,21H,2-3,5,9-13,15,26H2/t19-,21-/m0/s1 SLARGICHHUPLQU-FPOVZHCZSA-N 50125158 1-(2-Amino-4-bromo-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL352182 D(2) dopamine receptor Homo sapiens 4.7 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302454 104017392 CHEMBL352182 ZINC13488001 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226824 Fc1ccc(cc1)C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H27FN2OS/c25-18-9-7-17(8-10-18)22(28)5-2-12-26-14-11-21-20(16-26)19-4-1-6-23-24(19)27(21)13-3-15-29-23/h1,4,6-10,20-21H,2-3,5,11-16H2/t20-,21-/m0/s1 GHABYTRYIMZJAW-SFTDATJTSA-N 50125167 1-(4-Fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL352648 D(2) dopamine receptor Homo sapiens 8.8 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125167&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10072280 104017401 CHEMBL352648 ZINC00590308 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226827 Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3CCCCN2c13 InChI=1S/C25H30FN3O/c26-18-9-10-20(22(27)15-18)24(30)8-4-12-28-14-11-23-21(16-28)19-7-3-6-17-5-1-2-13-29(23)25(17)19/h3,6-7,9-10,15,21,23H,1-2,4-5,8,11-14,16,27H2/t21-,23-/m0/s1 HKELRUMBUSUQHV-GMAHTHKFSA-N 50125170 1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-4,5,6,7,8,9,11,11a-octahydro-7bH-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL349683 D(2) dopamine receptor Homo sapiens 3.5 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378369 104017404 CHEMBL349683 ZINC13488021 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226828 Nc1cc(Cl)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H28ClN3OS/c25-16-7-8-18(20(26)14-16)22(29)5-2-10-27-12-9-21-19(15-27)17-4-1-6-23-24(17)28(21)11-3-13-30-23/h1,4,6-8,14,19,21H,2-3,5,9-13,15,26H2/t19-,21-/m0/s1 NYDZDBFAMUDWJX-FPOVZHCZSA-N 50125157 1-(2-Amino-4-chloro-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL424384 D(2) dopamine receptor Homo sapiens 2.3 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125157&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302455 104017391 CHEMBL424384 ZINC13488000 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226829 Nc1c(F)cccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H28FN3OS/c25-19-7-1-6-17(23(19)26)21(29)8-3-11-27-13-10-20-18(15-27)16-5-2-9-22-24(16)28(20)12-4-14-30-22/h1-2,5-7,9,18,20H,3-4,8,10-15,26H2/t18-,20-/m0/s1 AXPPZNGPLKJAFR-ICSRJNTNSA-N 50125148 1-(2-Amino-3-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL165126 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125148&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302453 104017382 CHEMBL165126 ZINC13487997 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226831 Nc1ccccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H29N3OS/c25-20-8-2-1-6-18(20)22(28)9-4-12-26-14-11-21-19(16-26)17-7-3-10-23-24(17)27(21)13-5-15-29-23/h1-3,6-8,10,19,21H,4-5,9,11-16,25H2/t19-,21-/m1/s1 GXSDXKGIICWKIF-TZIWHRDSSA-N 50125152 1-(2-Amino-phenyl)-4-(7bR,11aS)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL444342 D(2) dopamine receptor Homo sapiens 5.9 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125152&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378076 104017386 CHEMBL444342 ZINC13488012 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226832 Nc1ccccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3CCCN2c13 InChI=1S/C24H29N3O/c25-21-10-2-1-8-19(21)23(28)11-5-13-26-15-12-22-20(16-26)18-9-3-6-17-7-4-14-27(22)24(17)18/h1-3,6,8-10,20,22H,4-5,7,11-16,25H2/t20-,22-/m1/s1 MADYDKSIUUGPRY-IFMALSPDSA-N 50125168 1-(2-Amino-phenyl)-4-(7aR,11aS)-5,6,8,9,11,11a-hexahydro-4H,7aH-pyrido[3',4':4,5]pyrrolo[3,2,1-ij]quinolin-10-yl-butan-1-one::CHEMBL352686 D(2) dopamine receptor Homo sapiens 63 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378002 104017402 CHEMBL352686 ZINC13488014 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226833 Nc1cc(O)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H29N3O2S/c25-20-14-16(28)7-8-18(20)22(29)5-2-10-26-12-9-21-19(15-26)17-4-1-6-23-24(17)27(21)11-3-13-30-23/h1,4,6-8,14,19,21,28H,2-3,5,9-13,15,25H2/t19-,21-/m0/s1 NKBKVACKOFITSD-FPOVZHCZSA-N 50125159 1-(2-Amino-4-hydroxy-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL164909 D(2) dopamine receptor Homo sapiens 50 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302456 104017393 CHEMBL164909 ZINC12356369 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226834 Fc1ccc(C(=O)CCCN2CC[C@H]3[C@@H](C2)c2cccc4SCCCN3c24)c(NC=O)c1 InChI=1S/C25H28FN3O2S/c26-17-7-8-19(21(14-17)27-16-30)23(31)5-2-10-28-12-9-22-20(15-28)18-4-1-6-24-25(18)29(22)11-3-13-32-24/h1,4,6-8,14,16,20,22H,2-3,5,9-13,15H2,(H,27,30)/t20-,22-/m0/s1 JPHKDUYQNMPCRA-UNMCSNQZSA-N 50125166 CHEMBL164744::N-[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butyryl)-phenyl]-formamide D(2) dopamine receptor Homo sapiens 7.7 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377939 104017400 CHEMBL164744 C06049 ZINC13488004 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226835 Nc1ccccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCN2c13 InChI=1S/C23H27N3OS/c24-19-7-2-1-5-17(19)21(27)8-4-11-25-12-10-20-18(15-25)16-6-3-9-22-23(16)26(20)13-14-28-22/h1-3,5-7,9,18,20H,4,8,10-15,24H2/t18-,20-/m0/s1 RGBZBUUBQUSTAD-ICSRJNTNSA-N 50125169 1-(2-Amino-phenyl)-4-(6bR,10aS)-1,2,6b,9,10,10a-hexahydro-7H-3-thia-8,10b-diaza-fluoranthen-8-yl-butan-1-one::CHEMBL163742 D(2) dopamine receptor Homo sapiens 41 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377928 104017403 CHEMBL163742 ZINC13488010 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226842 Nc1ccccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3SCCN2c13 InChI=1S/C23H27N3OS/c24-19-7-2-1-5-17(19)21(27)8-4-11-25-12-10-20-18(15-25)16-6-3-9-22-23(16)26(20)13-14-28-22/h1-3,5-7,9,18,20H,4,8,10-15,24H2/t18-,20-/m1/s1 RGBZBUUBQUSTAD-UYAOXDASSA-N 50125156 1-(2-Amino-phenyl)-4-(6bS,10aR)-1,2,6b,9,10,10a-hexahydro-7H-3-thia-8,10b-diaza-fluoranthen-8-yl-butan-1-one::CHEMBL351459 D(2) dopamine receptor Homo sapiens 19 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125156&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378035 104017390 CHEMBL351459 ZINC13488008 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226843 Nc1ccccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3OCCN2c13 InChI=1S/C23H27N3O2/c24-19-7-2-1-5-17(19)21(27)8-4-11-25-12-10-20-18(15-25)16-6-3-9-22-23(16)26(20)13-14-28-22/h1-3,5-7,9,18,20H,4,8,10-15,24H2/t18-,20-/m0/s1 LCGBVEYGRZPQEM-ICSRJNTNSA-N 50125171 1-(2-Amino-phenyl)-4-(6bR,10aS)-1,2,6b,9,10,10a-hexahydro-7H-3-oxa-8,10b-diaza-fluoranthen-8-yl-butan-1-one::CHEMBL351708 D(2) dopamine receptor Homo sapiens 23 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378024 104017405 CHEMBL351708 ZINC12356268 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226847 CNc1ccccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C25H31N3OS/c1-26-21-9-3-2-7-19(21)23(29)10-5-13-27-15-12-22-20(17-27)18-8-4-11-24-25(18)28(22)14-6-16-30-24/h2-4,7-9,11,20,22,26H,5-6,10,12-17H2,1H3/t20-,22-/m0/s1 OZTVZSHZOQCELD-UNMCSNQZSA-N 50125165 4-(7bS,11aR)-6,7,8,9,11,11a-Hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-1-(2-methylamino-phenyl)-butan-1-one::CHEMBL168051 D(2) dopamine receptor Homo sapiens 31 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302459 104017399 CHEMBL168051 ZINC13488002 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226858 O=C(CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13)c1ccccc1 InChI=1S/C24H28N2OS/c27-22(18-7-2-1-3-8-18)10-5-13-25-15-12-21-20(17-25)19-9-4-11-23-24(19)26(21)14-6-16-28-23/h1-4,7-9,11,20-21H,5-6,10,12-17H2/t20-,21-/m0/s1 JJEUGQSNWGGUIG-SFTDATJTSA-N 50125172 4-(7bS,11aR)-6,7,8,9,11,11a-Hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-1-phenyl-butan-1-one::CHEMBL350567 D(2) dopamine receptor Homo sapiens 17 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378128 104017406 CHEMBL350567 ZINC13487995 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226865 Nc1cc(F)ccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H28FN3OS/c25-16-7-8-18(20(26)14-16)22(29)5-2-10-27-12-9-21-19(15-27)17-4-1-6-23-24(17)28(21)11-3-13-30-23/h1,4,6-8,14,19,21H,2-3,5,9-13,15,26H2/t19-,21-/m1/s1 DPASSLWFBPICMV-TZIWHRDSSA-N 50125175 1-(2-Amino-4-fluoro-phenyl)-4-(7bR,11aS)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL349151 D(2) dopamine receptor Homo sapiens 4.7 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302471 104017409 CHEMBL349151 ZINC13488013 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226866 Nc1ccccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3CCCCN2c13 InChI=1S/C25H31N3O/c26-22-11-2-1-9-20(22)24(29)12-6-14-27-16-13-23-21(17-27)19-10-5-8-18-7-3-4-15-28(23)25(18)19/h1-2,5,8-11,21,23H,3-4,6-7,12-17,26H2/t21-,23-/m1/s1 IOXYLQYEPCUPNE-FYYLOGMGSA-N 50125179 1-(2-Amino-phenyl)-4-(7bR,11aS)-4,5,6,7,8,9,11,11a-octahydro-7bH-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL163261 D(2) dopamine receptor Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378348 104017413 CHEMBL163261 ZINC13488018 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226869 Nc1cc(F)ccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3SCCN2c13 InChI=1S/C23H26FN3OS/c24-15-6-7-17(19(25)13-15)21(28)4-2-9-26-10-8-20-18(14-26)16-3-1-5-22-23(16)27(20)11-12-29-22/h1,3,5-7,13,18,20H,2,4,8-12,14,25H2/t18-,20-/m1/s1 RFRAMVDLVRFQPK-UYAOXDASSA-N 50125176 1-(2-Amino-4-fluoro-phenyl)-4-(6bS,10aR)-1,2,6b,9,10,10a-hexahydro-7H-3-thia-8,10b-diaza-fluoranthen-8-yl-butan-1-one::CHEMBL351247 D(2) dopamine receptor Homo sapiens 14 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378034 104017410 CHEMBL351247 ZINC13488009 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226871 Nc1cc(F)ccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3CCCN2c13 InChI=1S/C24H28FN3O/c25-17-8-9-19(21(26)14-17)23(29)7-3-11-27-13-10-22-20(15-27)18-6-1-4-16-5-2-12-28(22)24(16)18/h1,4,6,8-9,14,20,22H,2-3,5,7,10-13,15,26H2/t20-,22-/m1/s1 HHUBBKQNDFELCT-IFMALSPDSA-N 50125164 1-(2-Amino-4-fluoro-phenyl)-4-(7aR,11aS)-5,6,8,9,11,11a-hexahydro-4H,7aH-pyrido[3',4':4,5]pyrrolo[3,2,1-ij]quinolin-10-yl-butan-1-one::CHEMBL163904 D(2) dopamine receptor Homo sapiens 29 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125164&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378001 104017398 CHEMBL163904 ZINC13488015 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226872 Nc1ccccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H29N3OS/c25-20-8-2-1-6-18(20)22(28)9-4-12-26-14-11-21-19(16-26)17-7-3-10-23-24(17)27(21)13-5-15-29-23/h1-3,6-8,10,19,21H,4-5,9,11-16,25H2/t19-,21-/m0/s1 GXSDXKGIICWKIF-FPOVZHCZSA-N 50125174 1-(2-Amino-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL164185 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302458 104017408 CHEMBL164185 ZINC13487996 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226873 CC(=O)Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C26H30FN3O2S/c1-17(31)28-22-15-18(27)8-9-20(22)24(32)6-3-11-29-13-10-23-21(16-29)19-5-2-7-25-26(19)30(23)12-4-14-33-25/h2,5,7-9,15,21,23H,3-4,6,10-14,16H2,1H3,(H,28,31)/t21-,23-/m0/s1 FHQYCPGXTQGPMU-GMAHTHKFSA-N 50125177 CHEMBL162768::N-[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butyryl)-phenyl]-acetamide D(2) dopamine receptor Homo sapiens 3.4 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377954 104017411 CHEMBL162768 ZINC13488003 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226878 Nc1ccccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3CCCN2c13 InChI=1S/C24H29N3O/c25-21-10-2-1-8-19(21)23(28)11-5-13-26-15-12-22-20(16-26)18-9-3-6-17-7-4-14-27(22)24(17)18/h1-3,6,8-10,20,22H,4-5,7,11-16,25H2/t20-,22-/m0/s1 MADYDKSIUUGPRY-UNMCSNQZSA-N 50125151 1-(2-Amino-phenyl)-4-(7aS,11aR)-5,6,8,9,11,11a-hexahydro-4H,7aH-pyrido[3',4':4,5]pyrrolo[3,2,1-ij]quinolin-10-yl-butan-1-one::CHEMBL348977 D(2) dopamine receptor Homo sapiens 68 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125151&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378016 104017385 CHEMBL348977 ZINC13488016 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226880 Nc1ccccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3OCCN2c13 InChI=1S/C23H27N3O2/c24-19-7-2-1-5-17(19)21(27)8-4-11-25-12-10-20-18(15-25)16-6-3-9-22-23(16)26(20)13-14-28-22/h1-3,5-7,9,18,20H,4,8,10-15,24H2/t18-,20-/m1/s1 LCGBVEYGRZPQEM-UYAOXDASSA-N 50125180 1-(2-Amino-phenyl)-4-(6bS,10aR)-1,2,6b,9,10,10a-hexahydro-7H-3-oxa-8,10b-diaza-fluoranthen-8-yl-butan-1-one::CHEMBL166366 D(2) dopamine receptor Homo sapiens 60 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125180&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378022 104017414 CHEMBL166366 ZINC13488022 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226887 Nc1cc(F)ccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3OCCN2c13 InChI=1S/C23H26FN3O2/c24-15-6-7-17(19(25)13-15)21(28)4-2-9-26-10-8-20-18(14-26)16-3-1-5-22-23(16)27(20)11-12-29-22/h1,3,5-7,13,18,20H,2,4,8-12,14,25H2/t18-,20-/m1/s1 LEDYBEGWCAWDCY-UYAOXDASSA-N 50125160 1-(2-Amino-4-fluoro-phenyl)-4-(6bS,10aR)-1,2,6b,9,10,10a-hexahydro-7H-3-oxa-8,10b-diaza-fluoranthen-8-yl-butan-1-one::CHEMBL349057 D(2) dopamine receptor Homo sapiens 16 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125160&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302447 104017394 CHEMBL349057 ZINC13488023 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226896 Nc1ccc(F)cc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C24H28FN3OS/c25-16-7-8-20(26)18(14-16)22(29)5-2-10-27-12-9-21-19(15-27)17-4-1-6-23-24(17)28(21)11-3-13-30-23/h1,4,6-8,14,19,21H,2-3,5,9-13,15,26H2/t19-,21-/m0/s1 GMUXLQLWEFMPIT-FPOVZHCZSA-N 50125178 1-(2-Amino-5-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL165723 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302457 104017412 CHEMBL165723 ZINC13487999 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226898 Nc1cc(F)ccc1C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3CCCCN2c13 InChI=1S/C25H30FN3O/c26-18-9-10-20(22(27)15-18)24(30)8-4-12-28-14-11-23-21(16-28)19-7-3-6-17-5-1-2-13-29(23)25(17)19/h3,6-7,9-10,15,21,23H,1-2,4-5,8,11-14,16,27H2/t21-,23-/m1/s1 HKELRUMBUSUQHV-FYYLOGMGSA-N 50125150 1-(2-Amino-4-fluoro-phenyl)-4-(7bR,11aS)-4,5,6,7,8,9,11,11a-octahydro-7bH-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butan-1-one::CHEMBL165897 D(2) dopamine receptor Homo sapiens 19 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378333 104017384 CHEMBL165897 ZINC13488019 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50226899 CCOC(=O)Nc1cc(F)ccc1C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCCN2c13 InChI=1S/C27H32FN3O3S/c1-2-34-27(33)29-22-16-18(28)9-10-20(22)24(32)7-4-12-30-14-11-23-21(17-30)19-6-3-8-25-26(19)31(23)13-5-15-35-25/h3,6,8-10,16,21,23H,2,4-5,7,11-15,17H2,1H3,(H,29,33)/t21-,23-/m0/s1 KALVMJJXXTWNQX-GMAHTHKFSA-N 50125153 CHEMBL164338::[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9,11,11a-hexahydro-5H,7bH-4-thia-7a,10-diaza-cyclohepta[jk]fluoren-10-yl-butyryl)-phenyl]-carbamic acid ethyl ester D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1016/s0960-894x(02)01028-4 10.7270/Q25H7FNW 12639577 Lee, T; Robichaud, AJ; Boyle, KE; Lu, Y; Robertson, DW; Miller, KJ; Fitzgerald, LW; McElroy, JF; Largent, BL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125153&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377965 104017387 CHEMBL164338 ZINC13488005 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240692 COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(cc2)[Sn](C(C)(C)C)(C(C)(C)C)C(C)(C)C)CC1 InChI=1S/C24H30N3O2.3C4H9.Sn/c1-29-23-12-6-5-11-22(23)27-19-17-26(18-20-27)16-8-7-15-25-24(28)14-13-21-9-3-2-4-10-21;3*1-4(2)3;/h3-6,9-14H,7-8,15-20H2,1H3,(H,25,28);3*1-3H3;/b14-13+;;;; WWMIPRIXMGNPTR-XURWPRCOSA-N 50132016 CHEMBL127020::N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-(4-tri-tert-butylstannanyl-phenyl)-acrylamide D(2) dopamine receptor Homo sapiens 729 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132016&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11146824 104023041 CHEMBL127020 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240693 COc1ccccc1N1CCN(CCCNC(=O)c2ccc(I)cc2)CC1 InChI=1S/C21H26IN3O2/c1-27-20-6-3-2-5-19(20)25-15-13-24(14-16-25)12-4-11-23-21(26)17-7-9-18(22)10-8-17/h2-3,5-10H,4,11-16H2,1H3,(H,23,26) GLMUYARIPQRMIW-UHFFFAOYSA-N 50132014 4-Iodo-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzamide::CHEMBL421667 D(2) dopamine receptor Homo sapiens 117 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132014&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11113582 104023039 CHEMBL421667 ZINC13526176 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240694 COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(Cl)cc2)CC1 InChI=1S/C22H28ClN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27) PZWHEQIOEMDZEH-UHFFFAOYSA-N 50007182 4-Chloro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide::CHEMBL126258::CHEMBL24515 D(2) dopamine receptor Homo sapiens 19.5 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2741842 103920465 CHEMBL126258CHEMBL24515 ZINC04364519 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240695 COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(I)cc2)CC1 InChI=1S/C24H30IN3O2/c1-30-23-7-3-2-6-22(23)28-18-16-27(17-19-28)15-5-4-14-26-24(29)13-10-20-8-11-21(25)12-9-20/h2-3,6-13H,4-5,14-19H2,1H3,(H,26,29)/b13-10+ MPTLULQFGUQHHY-JLHYYAGUSA-N 50132012 (E)-3-(4-Iodo-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide::3-(4-Iodo-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide::CHEMBL340712 D(2) dopamine receptor Homo sapiens 76.4 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9827991 104023037 CHEMBL340712 ZINC13526272 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240698 COc1ccccc1N1CCN(CCCN2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C22H25N3O3/c1-28-20-10-5-4-9-19(20)24-15-13-23(14-16-24)11-6-12-25-21(26)17-7-2-3-8-18(17)22(25)27/h2-5,7-10H,6,11-16H2,1H3 MDQWSMFPLDSLBV-UHFFFAOYSA-N 50132020 2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-isoindole-1,3-dione; oxalic acid::CHEMBL127979::CHEMBL26853 D(2) dopamine receptor Homo sapiens 300 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10249134 104023045 CHEMBL26853CHEMBL127979 ZINC13526371 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240699 COc1ccccc1N1CCN(CC1)C1CC2CC(CC2C1)NC1CC2CC(CC2C1)N1CCN(CC1)c1ccccc1OC InChI=1S/C38H55N5O2/c1-44-37-9-5-3-7-35(37)42-15-11-40(12-16-42)33-23-27-19-31(20-28(27)24-33)39-32-21-29-25-34(26-30(29)22-32)41-13-17-43(18-14-41)36-8-4-6-10-38(36)45-2/h3-10,27-34,39H,11-26H2,1-2H3 MLMPITXUNSOGFE-UHFFFAOYSA-N 50132021 Bis-{5-[4-(2-methoxy-phenyl)-piperazin-1-yl]-octahydro-pentalen-2-yl}-amine; oxalic acid::CHEMBL341481 D(2) dopamine receptor Homo sapiens 103 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10974122 104023046 CHEMBL341481 ZINC27304042 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240701 COc1ccccc1N1CCN(CCCCNC(=O)C2(CCCC2)c2ccc(Cl)cc2)CC1 InChI=1S/C27H36ClN3O2/c1-33-25-9-3-2-8-24(25)31-20-18-30(19-21-31)17-7-6-16-29-26(32)27(14-4-5-15-27)22-10-12-23(28)13-11-22/h2-3,8-13H,4-7,14-21H2,1H3,(H,29,32) FDRALTFJSNMYQH-UHFFFAOYSA-N 50132015 1-(4-Chloro-phenyl)-cyclopentanecarboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide; oxalic acid::CHEMBL127080 D(2) dopamine receptor Homo sapiens 56 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11005177 104023040 CHEMBL127080 ZINC13526234 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240702 COc1ccccc1N1CCN(CCCNC(=O)Cc2ccc3ccccc3c2)CC1 InChI=1S/C26H31N3O2/c1-31-25-10-5-4-9-24(25)29-17-15-28(16-18-29)14-6-13-27-26(30)20-21-11-12-22-7-2-3-8-23(22)19-21/h2-5,7-12,19H,6,13-18,20H2,1H3,(H,27,30) LCBLLUUMVDTFHY-UHFFFAOYSA-N 50132017 CHEMBL128133::N-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-2-naphthalen-2-yl-acetamide; oxalic acid D(2) dopamine receptor Homo sapiens 56 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11048013 104023042 CHEMBL128133 ZINC13526227 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240704 COc1ccccc1N1CCN(Cc2ccccc2CNC(=O)\C=C\c2ccccc2)CC1 InChI=1S/C28H31N3O2/c1-33-27-14-8-7-13-26(27)31-19-17-30(18-20-31)22-25-12-6-5-11-24(25)21-29-28(32)16-15-23-9-3-2-4-10-23/h2-16H,17-22H2,1H3,(H,29,32)/b16-15+ OUXSXBHPMQCPQT-FOCLMDBBSA-N 50132023 CHEMBL127234::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-3-phenyl-acrylamide D(2) dopamine receptor Homo sapiens 18 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132023&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11826347 104023048 CHEMBL127234 ZINC13526167 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240705 COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccccc2Cl)CC1 InChI=1S/C24H30ClN3O2/c1-30-23-11-5-4-10-22(23)28-18-16-27(17-19-28)15-7-6-14-26-24(29)13-12-20-8-2-3-9-21(20)25/h2-5,8-13H,6-7,14-19H2,1H3,(H,26,29)/b13-12+ VUZROXDIJDWGAH-OUKQBFOZSA-N 50132027 3-(2-Chloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide; oxalic acid::CHEMBL127654 D(2) dopamine receptor Homo sapiens 15 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11122812 104023052 CHEMBL127654 ZINC13526322 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240707 COc1ccccc1N1CCN(CCCCNC(=O)C2CC2c2ccccc2)CC1 InChI=1S/C25H33N3O2/c1-30-24-12-6-5-11-23(24)28-17-15-27(16-18-28)14-8-7-13-26-25(29)22-19-21(22)20-9-3-2-4-10-20/h2-6,9-12,21-22H,7-8,13-19H2,1H3,(H,26,29) PTPSBYOWELRFJR-UHFFFAOYSA-N 50132026 2-Phenyl-cyclopropanecarboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide; oxalic acid::CHEMBL127114 D(2) dopamine receptor Homo sapiens 81 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11732280 104023051 CHEMBL127114 ZINC13526250 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240709 COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(I)cc2)CC1 InChI=1S/C22H28IN3O2/c1-28-21-7-3-2-6-20(21)26-16-14-25(15-17-26)13-5-4-12-24-22(27)18-8-10-19(23)11-9-18/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,27) PZTFOAIQGVVNAX-UHFFFAOYSA-N 50007179 4-Iodo-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide::CHEMBL27254 D(2) dopamine receptor Homo sapiens 146 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10368423 103920462 CHEMBL27254 ZINC13526173 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240710 COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3oc2=O)CC1 InChI=1S/C25H29N3O4/c1-31-23-11-5-3-9-21(23)28-16-14-27(15-17-28)13-7-6-12-26-24(29)20-18-19-8-2-4-10-22(19)32-25(20)30/h2-5,8-11,18H,6-7,12-17H2,1H3,(H,26,29) UCVFOYIRJYVIDW-UHFFFAOYSA-N 50132025 2-Oxo-2H-chromene-3-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL126780::N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-2-oxo-2H-1-benzopyran-3-carboxamide D(2) dopamine receptor Homo sapiens 23 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10939008 104023050 CHEMBL126780 ZINC13526213 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240716 COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(\C=C\C(=O)NCCCCN3CCN(CC3)c3ccccc3OC)cc2)CC1 InChI=1S/C42H56N6O4/c1-51-39-13-5-3-11-37(39)47-31-27-45(28-32-47)25-9-7-23-43-41(49)21-19-35-15-17-36(18-16-35)20-22-42(50)44-24-8-10-26-46-29-33-48(34-30-46)38-12-4-6-14-40(38)52-2/h3-6,11-22H,7-10,23-34H2,1-2H3,(H,43,49)(H,44,50)/b21-19+,22-20+ ICGNIALTNZWGJF-FLFKKZLDSA-N 50132032 CHEMBL129035::N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-[4-(2-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butylcarbamoyl}-vinyl)-phenyl]-acrylamide D(2) dopamine receptor Homo sapiens 7.2 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10919602 104023057 CHEMBL129035 ZINC27308979 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240717 COc1ccccc1N1CCN(CCCCNC(=O)Cc2ccc3ccccc3c2)CC1 InChI=1S/C27H33N3O2/c1-32-26-11-5-4-10-25(26)30-18-16-29(17-19-30)15-7-6-14-28-27(31)21-22-12-13-23-8-2-3-9-24(23)20-22/h2-5,8-13,20H,6-7,14-19,21H2,1H3,(H,28,31) RGVVYJTVAURUOT-UHFFFAOYSA-N 50132034 CHEMBL339103::N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-2-naphthalen-2-yl-acetamide; oxalic acid D(2) dopamine receptor Homo sapiens 35 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11102080 104023059 CHEMBL339103 ZINC13526224 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240722 COc1ccc(\C=C\C(=O)NCCCCN2CCN(CC2)c2ccccc2OC)cc1 InChI=1S/C25H33N3O3/c1-30-22-12-9-21(10-13-22)11-14-25(29)26-15-5-6-16-27-17-19-28(20-18-27)23-7-3-4-8-24(23)31-2/h3-4,7-14H,5-6,15-20H2,1-2H3,(H,26,29)/b14-11+ PWYAMFWGADVMGC-SDNWHVSQSA-N 50132040 3-(4-Methoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide::CHEMBL127311 D(2) dopamine receptor Homo sapiens 12 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132040&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11091160 104023065 CHEMBL127311 ZINC13526288 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240725 COc1ccccc1N1CCN(CCCCNC(=O)c2sc3ccccc3c2Cl)CC1 InChI=1S/C24H28ClN3O2S/c1-30-20-10-4-3-9-19(20)28-16-14-27(15-17-28)13-7-6-12-26-24(29)23-22(25)18-8-2-5-11-21(18)31-23/h2-5,8-11H,6-7,12-17H2,1H3,(H,26,29) SFJPQQAKXJGNOP-UHFFFAOYSA-N 50132037 3-Chloro-benzo[b]thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL126313 D(2) dopamine receptor Homo sapiens 71.9 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11730189 104023062 CHEMBL126313 ZINC13526214 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240726 COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2cccc(I)c2)CC1 InChI=1S/C24H30IN3O2/c1-30-23-10-3-2-9-22(23)28-17-15-27(16-18-28)14-5-4-13-26-24(29)12-11-20-7-6-8-21(25)19-20/h2-3,6-12,19H,4-5,13-18H2,1H3,(H,26,29)/b12-11+ GJXPGIMBBKOOPF-VAWYXSNFSA-N 50132024 3-(3-Iodo-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide::CHEMBL338841 D(2) dopamine receptor Homo sapiens 161 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10994916 104023049 CHEMBL338841 ZINC13526310 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240728 COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(cc2)C(F)(F)F)CC1 InChI=1S/C25H30F3N3O2/c1-33-23-7-3-2-6-22(23)31-18-16-30(17-19-31)15-5-4-14-29-24(32)13-10-20-8-11-21(12-9-20)25(26,27)28/h2-3,6-13H,4-5,14-19H2,1H3,(H,29,32)/b13-10+ SJUYCGYJRSRZHG-JLHYYAGUSA-N 50132041 CHEMBL129429::N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-(4-trifluoromethyl-phenyl)-acrylamide D(2) dopamine receptor Homo sapiens 36.79 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11826673 104023066 CHEMBL129429 ZINC13526275 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240734 COc1ccccc1N1CCN(CC1)C1CC2CC(CC2C1)NC(=O)c1ccc2ccccc2c1 InChI=1S/C30H35N3O2/c1-35-29-9-5-4-8-28(29)33-14-12-32(13-15-33)27-19-24-17-26(18-25(24)20-27)31-30(34)23-11-10-21-6-2-3-7-22(21)16-23/h2-11,16,24-27H,12-15,17-20H2,1H3,(H,31,34) IQWDNJHMRMQNHR-UHFFFAOYSA-N 50132043 CHEMBL340313::Naphthalene-2-carboxylic acid {5-[4-(2-methoxy-phenyl)-piperazin-1-yl]-octahydro-pentalen-2-yl}-amide; oxalic acid D(2) dopamine receptor Homo sapiens 178 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10863645 104023068 CHEMBL340313 ZINC13526163 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240736 COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(o2)-c2ccc(Cl)cc2)CC1 InChI=1S/C26H30ClN3O3/c1-32-24-7-3-2-6-22(24)30-18-16-29(17-19-30)15-5-4-14-28-26(31)25-13-12-23(33-25)20-8-10-21(27)11-9-20/h2-3,6-13H,4-5,14-19H2,1H3,(H,28,31) CMEKWJGRDHWQSI-UHFFFAOYSA-N 50132029 5-(4-Chloro-phenyl)-furan-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide; oxalic acid::CHEMBL127029 D(2) dopamine receptor Homo sapiens 200 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132029&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11048937 104023054 CHEMBL127029 ZINC13526217 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240741 COc1cc(\C=C\C(=O)NCCCCN2CCN(CC2)c2ccccc2OC)cc(I)c1OC InChI=1S/C26H34IN3O4/c1-32-23-9-5-4-8-22(23)30-16-14-29(15-17-30)13-7-6-12-28-25(31)11-10-20-18-21(27)26(34-3)24(19-20)33-2/h4-5,8-11,18-19H,6-7,12-17H2,1-3H3,(H,28,31)/b11-10+ XTYMHPYTYMGIID-ZHACJKMWSA-N 50132048 3-(3-Iodo-4,5-dimethoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide; oxalic acid::CHEMBL127923 D(2) dopamine receptor Homo sapiens 38.5 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11767026 104023073 CHEMBL127923 ZINC27299325 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240742 COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc3ccccc3c2)CC1 InChI=1S/C28H33N3O2/c1-33-27-11-5-4-10-26(27)31-20-18-30(19-21-31)17-7-6-16-29-28(32)15-13-23-12-14-24-8-2-3-9-25(24)22-23/h2-5,8-15,22H,6-7,16-21H2,1H3,(H,29,32)/b15-13+ WZTXLKNXNIFASN-FYWRMAATSA-N 50132050 CHEMBL126749::N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-naphthalen-2-yl-acrylamide D(2) dopamine receptor Homo sapiens 32 ChEMBL 10.1021/jm030836n 10.7270/Q23F4P18 12930150 Hackling, A; Ghosh, R; Perachon, S; Mann, A; Holtje, HD; Wermuth, CG; Schwartz, JC; Sippl, W; Sokoloff, P; Stark, H Johann Wolfgang Goethe-Universität http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11102301 104023075 CHEMBL126749 ZINC13526363 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 7JVR,8IRS D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 50240743 COc1ccccc1N1CCN(CCCNC(=O)c2ccccc2I)CC1 InChI=1S/C21H