BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
147839	CC(=O)c1ccc2Sc3ccccc3Nc2c1	InChI=1S/C14H11NOS/c1-9(16)10-6-7-14-12(8-10)15-11-4-2-3-5-13(11)17-14/h2-8,15H,1H3	JWGBOHJGWOPYCL-UHFFFAOYSA-N	42323	1-(10H-phenothiazin-2-yl)ethanone::MLS000047624::SMR000033635::cid_81131	Alpha-2A adrenergic receptor		>10000								PubChem		10.7270/Q2RB732P		aid504410		PubChem, PC	The Scripps Research Institute Molecular Screening Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42323&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			81131	252623027						ZINC00119687	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
157180	Clc1cccc(c1)N1CCNCC1	InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2	VHFVKMTVMIZMIK-UHFFFAOYSA-N	50001915	1-(3-chlorophenyl)piperazine::CHEMBL478::m-Chlorophenylpiperazine::mCPP	Alpha-2A adrenergic receptor		 570								PDSP Ki	10.1016/0006-3223(89)90217-5	10.7270/Q2MP51R8	2537663			Hamik, A; Peroutka, SJ	Stanford University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001915	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001915&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1355	103916282	10588	CHEMBL478		142	C11738	ZINC00004285	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155156	COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1	InChI=1S/C25H30N2O3/c1-25(2)20-9-5-4-8-18(20)23(28)19(24(25)29)12-13-26-14-16-27(17-15-26)21-10-6-7-11-22(21)30-3/h4-11,19H,12-17H2,1-3H3	OSEADGVOKYGIER-UHFFFAOYSA-N	81772	ARC-239::CAS_122211::NSC_122211	Alpha-2A adrenergic receptor		 171								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81772&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122211	131342346				524		ZINC60027297	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155157	COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19+/m0/s1	GRTOGORTSDXSFK-BMYCAMMWSA-N	50030622	(7aS,8S,11aS,12aR)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester::AKUAMMIGINE::CHEMBL122404	Alpha-2A adrenergic receptor		 71								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030622&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1268096	103939471		CHEMBL122404				ZINC53174616	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155158	COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19+/m0/s1	GRTOGORTSDXSFK-BMYCAMMWSA-N	50030622	(7aS,8S,11aS,12aR)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester::AKUAMMIGINE::CHEMBL122404	Alpha-2A adrenergic receptor		 104								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030622&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1268096	103939471		CHEMBL122404				ZINC53174616	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155159	CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13	InChI=1S/C25H25BrN4/c1-29-14-16(15-30-11-10-27-25(30)17-6-3-2-4-7-17)12-19-18-8-5-9-21-23(18)20(13-22(19)29)24(26)28-21/h2-11,16,19,22,28H,12-15H2,1H3/t16-,19-,22-/m1/s1	VKABNRMTNPWHBD-ZWDAVXSWSA-N	81773	BAM 1303::BAM-1303::CAS_115219-10-8	Alpha-2A adrenergic receptor		 0.39								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81773&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344262	131342347						ZINC38563583	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155160	CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13	InChI=1S/C25H25BrN4/c1-29-14-16(15-30-11-10-27-25(30)17-6-3-2-4-7-17)12-19-18-8-5-9-21-23(18)20(13-22(19)29)24(26)28-21/h2-11,16,19,22,28H,12-15H2,1H3/t16-,19-,22-/m1/s1	VKABNRMTNPWHBD-ZWDAVXSWSA-N	81773	BAM 1303::BAM-1303::CAS_115219-10-8	Alpha-2A adrenergic receptor		 1.34								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81773&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344262	131342347						ZINC38563583	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155161	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2A adrenergic receptor		 78								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155162	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2A adrenergic receptor		 253								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155163	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 3.3								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155164	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 1.45								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155165	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 4.1								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155166	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 4.22								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155167	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 302								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155168	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 316								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155169	COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3	GRTOGORTSDXSFK-UHFFFAOYSA-N	30993	Ajmalicine::MLS000111555::Raubasine::SMR000107477::cid_251561	Alpha-2A adrenergic receptor		 6.4								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30993&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	AJN	4WNT	251561	242052838							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155170	COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3	GRTOGORTSDXSFK-UHFFFAOYSA-N	30993	Ajmalicine::MLS000111555::Raubasine::SMR000107477::cid_251561	Alpha-2A adrenergic receptor		 8.9								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30993&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	AJN	4WNT	251561	242052838							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155171	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.32								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155172	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.44								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155173	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2A adrenergic receptor		 5.5								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155174	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2A adrenergic receptor		 8.3								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155175	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2A adrenergic receptor		 0.91								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155176	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2A adrenergic receptor		 1.27								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155177	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.5								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155178	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.65								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158013	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2A adrenergic receptor		 769.23								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158014	CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	ZUXABONWMNSFBN-UHFFFAOYSA-N	22869	6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine	Alpha-2A adrenergic receptor		 161.29								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	49846683				38		ZINC19796155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158015	CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34	InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	ZZJYIKPMDIWRSN-HWBMXIPRSA-N	50008735	(+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol	Alpha-2A adrenergic receptor		 312.5								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			37459	103921865		CHEMBL8514		62		ZINC02008410	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158016	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2	PLDUPXSUYLZYBN-UHFFFAOYSA-N	78433	2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17	Alpha-2A adrenergic receptor		 1562.5								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3372	252655189			DB00623		C07010	ZINC19203912	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158017	OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1	InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	LNEPOXFFQSENCJ-UHFFFAOYSA-N	21398	4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1	Alpha-2A adrenergic receptor		 3846.15								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	GMJ	6X10,6DJZ,6LUQ	3559	49689470	5613	CHEMBL54CHEMBL545608	DB00502	86	C01814	ZINC00537822	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158018	CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12	InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3	XJGVXQDUIWGIRW-UHFFFAOYSA-N	22871	13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine	Alpha-2A adrenergic receptor		 2380.95								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3964	49846685	50841	CHEMBL831	DB00408	205	C07104	ZINC19796158	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158019	CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O	InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3	SLVMESMUVMCQIY-UHFFFAOYSA-N	50131440	10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23	Alpha-2A adrenergic receptor		 1612.9								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131440&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4078	104022598	6780	CHEMBL1088	DB00933	7227	C07143	ZINC03831042	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158020	CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12	InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3	KLPWJLBORRMFGK-UHFFFAOYSA-N	50130290	3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban	Alpha-2A adrenergic receptor		 625								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23897	104021724		CHEMBL460	DB01618	207	C07230	ZINC22002218	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158021	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1	InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2	RGCVKNLCSQQDEP-UHFFFAOYSA-N	50130273	2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine	Alpha-2A adrenergic receptor		 500								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4748	104021707	8028	CHEMBL567	DB00850	209	C07427	ZINC19228902	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158022	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 43.47								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158023	CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1	InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3	WIKYUJGCLQQFNW-UHFFFAOYSA-N	78434	2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499	Alpha-2A adrenergic receptor		 1694.91								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	P77	3M0W	4917	252655190	8435		DB00433		C07403	ZINC19796018	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158024	CN(C)CCCN1c2ccccc2Sc2ccccc12	InChI=1S/C17H20N2S/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19/h3-6,8-11H,7,12-13H2,1-2H3	ZGUGWUXLJSTTMA-UHFFFAOYSA-N	67545	N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride::PROMAZINE::SR-01000000228-4::US9504692, Promazine::cid_5887::dimethyl(3-phenothiazin-10-ylpropyl)amine;hydrochloride	Alpha-2A adrenergic receptor		 909.09								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67545&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	P2Z	7LGI,4MA7	4926	252645840			DB00420		C07379	ZINC00010402	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158025	Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1	InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)	DKGZKTPJOSAWFA-UHFFFAOYSA-N	21397	8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265	Alpha-2A adrenergic receptor		 666.66								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SIP	7DFP	5265	49689469	9233	CHEMBL267930		99		ZINC00643233	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158026	CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1	InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3	KLBQZWRITKRQQV-UHFFFAOYSA-N	50002338	(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine	Alpha-2A adrenergic receptor		 833.33								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LZU	4I1R,4UHX	5452	103916644	9566	CHEMBL479	DB00679	100		ZINC01530697	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158027	CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1	InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8-	GFBKORZTTCHDGY-UWVJOHFNSA-N	78576	CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene	Alpha-2A adrenergic receptor		 200								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78576&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			941651	252655323			DB01623	212		ZINC30690433	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158028	CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3	ZEWQUBUPAILYHI-UHFFFAOYSA-N	79181	10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566	Alpha-2A adrenergic receptor		 2631.57								PDSP Ki	10.1111/j.1749-6632.1988.tb42125.x	10.7270/Q2X065JH	2904784			Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TFP	4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0	5566	252655893			DB00831		C07168	ZINC19418959	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155520	CCCN(CCC)C1CCc2cccc(O)c2C1	InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	ASXGJMSKWNBENU-UHFFFAOYSA-N	21393	7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220	Alpha-2A adrenergic receptor		 186								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1220	49689465	73364	CHEMBL1788118CHEMBL505765CHEMBL56		31		ZINC03870313	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155521	COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19+/m0/s1	GRTOGORTSDXSFK-BMYCAMMWSA-N	50030622	(7aS,8S,11aS,12aR)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester::AKUAMMIGINE::CHEMBL122404	Alpha-2A adrenergic receptor		 130								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030622&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1268096	103939471		CHEMBL122404				ZINC53174616	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155522	COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1	InChI=1S/C25H30N2O3/c1-25(2)20-9-5-4-8-18(20)23(28)19(24(25)29)12-13-26-14-16-27(17-15-26)21-10-6-7-11-22(21)30-3/h4-11,19H,12-17H2,1-3H3	OSEADGVOKYGIER-UHFFFAOYSA-N	81772	ARC-239::CAS_122211::NSC_122211	Alpha-2A adrenergic receptor		 171								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81772&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122211	131342346				524		ZINC60027297	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155523	CCC1(Cc2ccccc2C1)c1cnc[nH]1	InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)	HSWPZIDYAHLZDD-UHFFFAOYSA-N	81807	ATIPAMEZOLE::CAS_104054-27-5::NSC_71310	Alpha-2A adrenergic receptor		 0.33								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81807&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71310	131342381						ZINC05424171	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155524	C=CCN1Cc2ccccc2-c2ccccc2C1	InChI=1S/C17H17N/c1-2-11-18-12-14-7-3-5-9-16(14)17-10-6-4-8-15(17)13-18/h2-10H,1,11-13H2	NYGHGTMKALXFIA-UHFFFAOYSA-N	81805	AZAPETINE::CAS_130-83-6::NSC_8966	Alpha-2A adrenergic receptor		 38								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81805&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8966	131342379						ZINC01481977	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155525	CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13	InChI=1S/C25H25BrN4/c1-29-14-16(15-30-11-10-27-25(30)17-6-3-2-4-7-17)12-19-18-8-5-9-21-23(18)20(13-22(19)29)24(26)28-21/h2-11,16,19,22,28H,12-15H2,1H3/t16-,19-,22-/m1/s1	VKABNRMTNPWHBD-ZWDAVXSWSA-N	81773	BAM 1303::BAM-1303::CAS_115219-10-8	Alpha-2A adrenergic receptor		 2.5								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81773&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344262	131342347						ZINC38563583	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155526	Clc1cccc2CN(Cc12)N=C1NCCN1	InChI=1S/C11H13ClN4/c12-10-3-1-2-8-6-16(7-9(8)10)15-11-13-4-5-14-11/h1-3H,4-7H2,(H2,13,14,15)	OYLPBTPLAUXYTB-UHFFFAOYSA-N	81804	4-chloro-2-(2-imidazolin-2-ylamino)isoindoline::BDF6143::CAS_76727-72-5	Alpha-2A adrenergic receptor		 0.06								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81804&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			131284	131342378						ZINC06093764	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155527	Oc1ccc(CCNCC2CCc3ccccc3C2=O)cc1	InChI=1S/C19H21NO2/c21-17-9-5-14(6-10-17)11-12-20-13-16-8-7-15-3-1-2-4-18(15)19(16)22/h1-6,9-10,16,20-21H,7-8,11-13H2	PZZOEXPDTYIBPI-UHFFFAOYSA-N	81809	BE-2254::CAS_34772::NSC_34772	Alpha-2A adrenergic receptor		 0.93								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81809&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			34772	131342383						ZINC02011295	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155528	CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34	InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	ZZJYIKPMDIWRSN-HWBMXIPRSA-N	50008735	(+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol	Alpha-2A adrenergic receptor		 53								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			37459	103921865		CHEMBL8514		62		ZINC02008410	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155529	CN1CCN(CC1)C1=Nc2ccccc2Sc2nccn12	InChI=1S/C15H17N5S/c1-18-8-10-19(11-9-18)14-17-12-4-2-3-5-13(12)21-15-16-6-7-20(14)15/h2-7H,8-11H2,1H3	FACMWMBWGSPRKO-UHFFFAOYSA-N	81802	CAS_81382-52-7::CGS-10746B::CGS10746B::PENTIAPINE MALEATE	Alpha-2A adrenergic receptor		 3600								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81802&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54742	131342376						ZINC30690661	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155530	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2A adrenergic receptor		 254								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155531	CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	ZUXABONWMNSFBN-UHFFFAOYSA-N	22869	6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine	Alpha-2A adrenergic receptor		 24								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	49846683				38		ZINC19796155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155532	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 132								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155533	Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12	InChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2	TVURRHSHRRELCG-UHFFFAOYSA-N	60917	9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::FENOLDOPAM::FENOLDOPAM MESYLATE::MLS001401388::SMR000469190::cid_49659	Alpha-2A adrenergic receptor		 16								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60917&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	G3C	7CKW,7X2C	3341	252640133			DB00800		C07693	ZINC22116612	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155534	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2	PLDUPXSUYLZYBN-UHFFFAOYSA-N	78433	2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17	Alpha-2A adrenergic receptor		 304								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3372	252655189			DB00623		C07010	ZINC19203912	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155535	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2A adrenergic receptor		 1.9								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155536	Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1	InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)	FPCCSQOGAWCVBH-UHFFFAOYSA-N	21395	3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin	Alpha-2A adrenergic receptor		 372								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3822	49689467	6123	CHEMBL51CHEMBL1628637		197	C07464	ZINC00537877	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155537	Clc1cncc(n1)N1CCNCC1	InChI=1S/C8H11ClN4/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2	CJAWPFJGFFNXQI-UHFFFAOYSA-N	50017452	2-chloro-6-piperazin-1-ylpyrazine::6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl::6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl(MK-212)::CHEMBL269521::L-630,571::MK 212::MK-212	Alpha-2A adrenergic receptor		 153								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017452&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			107992	103928720		CHEMBL269521		165		ZINC01571800	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155538	C1CN(CCN1)c1nccn2ccnc12	InChI=1S/C10H13N5/c1-5-14(6-2-11-1)9-10-13-4-8-15(10)7-3-12-9/h3-4,7-8,11H,1-2,5-6H2	NSHLOJVJEGEMSF-UHFFFAOYSA-N	50002151	8-Piperazin-1-yl-imidazo[1,2-a]pyrazine::CHEMBL331036::L-639,019	Alpha-2A adrenergic receptor		 35								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002151&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			131268	103916457		CHEMBL331036				ZINC05117657	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155539	Fc1cccnc1N1CCNCC1	InChI=1S/C9H12FN3/c10-8-2-1-3-12-9(8)13-6-4-11-5-7-13/h1-3,11H,4-7H2	HPYRNHPSWLCJKD-UHFFFAOYSA-N	50027024	1-(3-Fluoro-pyridin-2-yl)-piperazine::CHEMBL48833::L-644,763	Alpha-2A adrenergic receptor		 20								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027024&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			134987	103936608		CHEMBL48833				ZINC26898952	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155540	CCOc1ccc(CC(NC(=O)CC2(S)CCCCC2)C(=O)NC(Cc2ccccc2)C(=O)NC(C(C)C)C(=O)NC(CC(N)=O)C(=O)NC(C=S)C(=O)NC(CCCCN)C(N)=O)cc1	InChI=1S/C46H67N9O9S2/c1-4-64-31-18-16-30(17-19-31)24-33(50-38(57)26-46(66)20-10-6-11-21-46)41(59)52-34(23-29-13-7-5-8-14-29)43(61)55-39(28(2)3)45(63)53-35(25-37(48)56)42(60)54-36(27-65)44(62)51-32(40(49)58)15-9-12-22-47/h5,7-8,13-14,16-19,27-28,32-36,39,66H,4,6,9-12,15,20-26,47H2,1-3H3,(H2,48,56)(H2,49,58)(H,50,57)(H,51,62)(H,52,59)(H,53,63)(H,54,60)(H,55,61)	VNEOOMJYPUDQOL-UHFFFAOYSA-N	81815	CAS_196343::L-654,284::NSC_196343	Alpha-2A adrenergic receptor		 0.36								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81815&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53463783	131342389							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155541	CN1CCC2(CCN3CCc4c(oc5ccccc45)C3C2)N(C)C1=O	InChI=1S/C20H25N3O2/c1-21-11-8-20(22(2)19(21)24)9-12-23-10-7-15-14-5-3-4-6-17(14)25-18(15)16(23)13-20/h3-6,16H,7-13H2,1-2H3	JRDUBBHIPPPSLP-UHFFFAOYSA-N	81811	CAS_123679::L-657,743::MK-912::NSC_123679	Alpha-2A adrenergic receptor		 0.42								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81811&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			123679	131342385						ZINC04475284	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155542	CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1	UEQUQVLFIPOEMF-GOSISDBHSA-N	35256	(S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon	Alpha-2A adrenergic receptor		 5.2								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			154315	85753335	51137					ZINC00000855	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155543	CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1	UEQUQVLFIPOEMF-GOSISDBHSA-N	35256	(S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon	Alpha-2A adrenergic receptor		 46								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			154315	85753335	51137					ZINC00000855	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155544	Cc1cccc(C)c1CCc1cnc[nH]1	InChI=1S/C13H16N2/c1-10-4-3-5-11(2)13(10)7-6-12-8-14-9-15-12/h3-5,8-9H,6-7H2,1-2H3,(H,14,15)	WRAZSLKGTVFTSN-UHFFFAOYSA-N	81813	CAS_133305::MPV 295::NSC_133305	Alpha-2A adrenergic receptor		 8.7								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81813&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133305	131342387						ZINC05116308	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155545	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 0.79								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155546	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 6								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155547	C(C1COc2ccccc2O1)N1CCCCC1	InChI=1S/C14H19NO2/c1-4-8-15(9-5-1)10-12-11-16-13-6-2-3-7-14(13)17-12/h2-3,6-7,12H,1,4-5,8-11H2	LYKMMUBOEFYJQG-UHFFFAOYSA-N	50017720	1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidine::1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidine(Piperoxan)::CHEMBL31836::PIPEROXAN1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidine::Piperoxan	Alpha-2A adrenergic receptor		 5.4								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017720&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6040	103928988		CHEMBL31836				ZINC01019594	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155548	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 316								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155549	COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3	GRTOGORTSDXSFK-UHFFFAOYSA-N	30993	Ajmalicine::MLS000111555::Raubasine::SMR000107477::cid_251561	Alpha-2A adrenergic receptor		 8.9								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30993&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	AJN	4WNT	251561	242052838							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155550	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.44								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155551	CCOC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C13H16N2O3/c1-2-17-13(12-14-7-8-15-12)9-16-10-5-3-4-6-11(10)18-13/h3-6H,2,7-9H2,1H3,(H,14,15)	PXTLRBYNGGDZBN-UHFFFAOYSA-N	81803	CAS_125992::NSC_125992::RX 811033	Alpha-2A adrenergic receptor		 0.2								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81803&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			125992	131342377						ZINC03798255	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155552	Cc1nc2SCCn2c(=O)c1CCN1CCC(CC1)C(=O)c1ccc(F)cc1	InChI=1S/C21H24FN3O2S/c1-14-18(20(27)25-12-13-28-21(25)23-14)8-11-24-9-6-16(7-10-24)19(26)15-2-4-17(22)5-3-15/h2-5,16H,6-13H2,1H3	RBGAHDDQSRBDOG-UHFFFAOYSA-N	81814	5H-THIAZOLO[3,2A]PYRIMIDIN-5-ONE, 6-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,3-DIHYDRO-7-METHYL-::CAS_86487-64-1::SEPTOPERONE::SETOPERONE	Alpha-2A adrenergic receptor		 90								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81814&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68604	131342388						ZINC00538339	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155553	CN1CCc2c(Cl)ccc(OCC=C(C)C)c2CC1	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3	MBYSTKNEMJZSIK-UHFFFAOYSA-N	50030623	6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL114166::SK&F-104078::SK-104078::SKF 104078	Alpha-2A adrenergic receptor		 32								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030623&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122295	103939472		CHEMBL114166				ZINC05158824	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155554	CN1CCc2cccc(Cl)c2CC1	InChI=1S/C11H14ClN/c1-13-7-5-9-3-2-4-11(12)10(9)6-8-13/h2-4H,5-8H2,1H3	RSRUDTPYRBLHEO-UHFFFAOYSA-N	66983	6-chloranyl-3-methyl-1,2,4,5-tetrahydro-3-benzazepine;hydrochloride::6-chloro-3-methyl-1,2,4,5-tetrahydro-3-benzazepine;hydrochloride::CHEMBL123349::MLS002172470::SKF 86466::SKF-86466 hydrochloride::SMR001254100::cid_10220250	Alpha-2A adrenergic receptor		 2.4								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66983	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66983&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			123981	252645294		CHEMBL123349			C10970	ZINC00900633	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155555	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2A adrenergic receptor		 13								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155556	COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3	GRTOGORTSDXSFK-UHFFFAOYSA-N	30993	Ajmalicine::MLS000111555::Raubasine::SMR000107477::cid_251561	Alpha-2A adrenergic receptor		 0.66								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30993&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	AJN	4WNT	251561	242052838							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155557	CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1	InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3	KLBQZWRITKRQQV-UHFFFAOYSA-N	50002338	(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine	Alpha-2A adrenergic receptor		 453								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LZU	4I1R,4UHX	5452	103916644	9566	CHEMBL479	DB00679	100		ZINC01530697	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155558	Clc1ccc2nsnc2c1NC1=NCCN1	InChI=1S/C9H8ClN5S/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9/h1-2H,3-4H2,(H2,11,12,13)	XFYDIVBRZNQMJC-UHFFFAOYSA-N	50240671	(5-Chloro-benzo[1,2,5]thiadiazol-4-yl)-(4,5-dihydro-1H-imidazol-2-yl)-amine::CHEMBL1079::TIZANIDINE::Zanaflex	Alpha-2A adrenergic receptor		 62								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240671&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5487	104098410	63629	CHEMBL1079	DB00697	7308	C07452	ZINC19702309	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155559	C(C1=NCCN1)c1ccccc1	InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12)	JIVZKJJQOZQXQB-UHFFFAOYSA-N	55436	2-(phenylmethyl)-4,5-dihydro-1H-imidazole;hydrochloride::2-Benzyl-4,5-dihydro-1H-imidazole::2-benzyl-2-imidazoline;hydrochloride::2-benzyl-4,5-dihydro-1H-imidazole;hydrochloride::MLS000559484::SMR000149600::Tolazoline::cid_6048	Alpha-2A adrenergic receptor		 24								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55436&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5504	252635433	28502		DB00797		C07147	ZINC00125006	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155560	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2A adrenergic receptor		 1.2								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155561	CN1C(Cc2cc(F)ccc12)C1=NCCN1	InChI=1S/C12H14FN3/c1-16-10-3-2-9(13)6-8(10)7-11(16)12-14-4-5-15-12/h2-3,6,11H,4-5,7H2,1H3,(H,14,15)	NSRZNUWGDARAEO-UHFFFAOYSA-N	50019855	2-(4,5-Dihydro-1H-imidazol-2-yl)-5-fluoro-1-methyl-2,3-dihydro-1H-indole::CHEMBL41720::WIN 52664	Alpha-2A adrenergic receptor		 0.4								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019855	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019855&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13869749	103930778		CHEMBL41720				ZINC29339874	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155562	C=CCn1c(cc2ccccc12)C1=NCCN1	InChI=1S/C14H15N3/c1-2-9-17-12-6-4-3-5-11(12)10-13(17)14-15-7-8-16-14/h2-6,10H,1,7-9H2,(H,15,16)	CUOQKQBYZYMBSP-UHFFFAOYSA-N	81806	2-(4,5-dihydro-1h-imidazol-2-yl)-2,3-dihydro-1-(2-propenyl)-1h-indole mono(4-methylbenzenesulfonate)::WIN 53024::WIN 53782	Alpha-2A adrenergic receptor		 0.05								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81806&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53741044	131342380						ZINC00016283	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155563	C=CCn1c(cc2ccccc12)C1=NCCN1	InChI=1S/C14H15N3/c1-2-9-17-12-6-4-3-5-11(12)10-13(17)14-15-7-8-16-14/h2-6,10H,1,7-9H2,(H,15,16)	CUOQKQBYZYMBSP-UHFFFAOYSA-N	81806	2-(4,5-dihydro-1h-imidazol-2-yl)-2,3-dihydro-1-(2-propenyl)-1h-indole mono(4-methylbenzenesulfonate)::WIN 53024::WIN 53782	Alpha-2A adrenergic receptor		 4.8								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81806&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53741044	131342380						ZINC00016283	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155564	CCCS(=O)(=O)N(C)C1CCN2CCc3ccccc3C2C1	InChI=1S/C17H26N2O2S/c1-3-12-22(20,21)18(2)15-9-11-19-10-8-14-6-4-5-7-16(14)17(19)13-15/h4-7,15,17H,3,8-13H2,1-2H3	LJPDFKRYOKWXMQ-UHFFFAOYSA-N	81808	CAS_133816::NSC_133816::WY 26392	Alpha-2A adrenergic receptor		 2.2								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81808&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10041833	131342382						ZINC14953373	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155565	CS(=O)(=O)NCCN(C1CCN2CCc3ccccc3C2C1)S(C)(=O)=O	InChI=1S/C17H27N3O4S2/c1-25(21,22)18-9-12-20(26(2,23)24)15-8-11-19-10-7-14-5-3-4-6-16(14)17(19)13-15/h3-6,15,17-18H,7-13H2,1-2H3	VSQCTWPNMPWYSD-UHFFFAOYSA-N	81810	CAS_125697::NSC_125697::WY 27127	Alpha-2A adrenergic receptor		 11								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81810&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13336656	131342384						ZINC14953689	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155566	CCCCS(=O)(=O)N(C)[C@H]1CCN2CCc3ccccc3[C@H]2C1	InChI=1S/C18H28N2O2S/c1-3-4-13-23(21,22)19(2)16-10-12-20-11-9-15-7-5-6-8-17(15)18(20)14-16/h5-8,16,18H,3-4,9-14H2,1-2H3/t16-,18+/m0/s1	LVHNKZNYJNTKDF-FUHWJXTLSA-N	81816	AC1L33GU::AR-1K2981::CAS_82059-49-2::N-[(2S,11bR)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]-N-methylbutane-1-sulfonamide hydrochloride::WY26703	Alpha-2A adrenergic receptor		 1.4								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81816&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133820	131342390						ZINC05821628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
155567	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.65								PDSP Ki		10.7270/Q2Z899WV	1656026			Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161242	CN(C)Cc1nnc2CN=C(c3ccccc3)c3cc(Cl)ccc3-n12	InChI=1S/C19H18ClN5/c1-24(2)12-18-23-22-17-11-21-19(13-6-4-3-5-7-13)15-10-14(20)8-9-16(15)25(17)18/h3-10H,11-12H2,1-2H3	GJSLOMWRLALDCT-UHFFFAOYSA-N	82439	Adinazolam::CAS_37115-32-5::NSC_37632	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82439&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			37632	136350410	251412		DB00546			ZINC04214740	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161243	CN(C)CCC=C1c2ccccc2CCc2ccccc12	InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3	KRMDCWKBEZIMAB-UHFFFAOYSA-N	50020712	10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene::10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine::3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine::3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine::3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine::5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene::5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene::5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene::AMITRIPTYLINE::Amitriptylin::CHEMBL629	Alpha-2A adrenergic receptor	Homo sapiens	 690								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TP0    	8Y93,5HA9,3APV	2160	103931468	2666	CHEMBL629	DB00321	200	C06824	ZINC00968257	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161244	CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1	InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3	SNPPWIUOZRMYNY-UHFFFAOYSA-N	50048392	2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one::BUPROPION::BUPROPION HYDROCHLORIDE::CHEMBL894::US9944618, Compound ID No. 176	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048392&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			444	103978858	3219	CHEMBL894	DB01156	7135	C06860	ZINC00057206	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161245	CNCCCN1c2ccccc2CCc2ccccc12	InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3	HCYAFALTSJYZDH-UHFFFAOYSA-N	35229	3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine::5-(gamma-methylaminopropyl)iminodibenzyl::CHEMBL72::DESIPRAMINE HYDROCHLORIDE::DMI::Desipramin::Desipramine::Desmethylimipramine::N-(3-methylaminopropyl)iminobibenzyl::US9944618, Compound ID No. 174::demethylimipramine::monodemethylimipramine::norimipramine	Alpha-2A adrenergic receptor		 5500								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35229&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	DSM	7Q19,2QJU,7Q2N,7Q2O,7Q2P,2QB4	2995	85753308	47781	CHEMBL72	DB01151	2399	C06943	ZINC01530611	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161246	N[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc12	InChI=1S/C16H15Cl2N/c17-14-7-5-10(9-15(14)18)11-6-8-16(19)13-4-2-1-3-12(11)13/h1-5,7,9,11,16H,6,8,19H2/t11-,16-/m0/s1	SRPXSILJHWNFMK-ZBEGNZNMSA-N	50028066	4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-ylamine, HCl::CHEMBL40733::Desmethylsertraline	Alpha-2A adrenergic receptor		 7800								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028066	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028066&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			114743	103937445		CHEMBL40733				ZINC06117444	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161247	CN(C)CC\C=C1\c2ccccc2COc2ccccc12	InChI=1S/C19H21NO/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3/b17-11-	ODQWQRRAPPTVAG-BOPFTXTBSA-N	50079527	(3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine(3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine::CHEMBL101740::DOXEPIN::cis-doxepin	Alpha-2A adrenergic receptor		 1270								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079527&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	D7V	3RZE	667468	103971748	4710	CHEMBL101740			C06971	ZINC00001148	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161248	CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CC	InChI=1S/C19H28ClN5O/c1-3-18-21-25(19(26)24(18)4-2)10-6-9-22-11-13-23(14-12-22)17-8-5-7-16(20)15-17/h5,7-8,15H,3-4,6,9-14H2,1-2H3	IZBNNCFOBMGTQX-UHFFFAOYSA-N	82438	CAS_52942-31-1::Etoperidone::NSC_40589	Alpha-2A adrenergic receptor		 570								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82438&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			40589	136350409			DB09194			ZINC03830815	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161249	COc1ccc(OC[C@H]2CN(C)CC[C@@H]2c2ccccc2)cc1	InChI=1S/C20H25NO2/c1-21-13-12-20(16-6-4-3-5-7-16)17(14-21)15-23-19-10-8-18(22-2)9-11-19/h3-11,17,20H,12-15H2,1-2H3/t17-,20-/m1/s1	OJSFTALXCYKKFQ-YLJYHZDGSA-N	50014247	(3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phenyl-piperidine::3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phenyl-piperidine(femoxetine)::CHEMBL94739::Femoxetine	Alpha-2A adrenergic receptor		 1970								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014247&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3012003	103926269		CHEMBL94739				ZINC04216004	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161250	CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1	InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3	RTHCYVBBDHJXIQ-UHFFFAOYSA-N	30130	CHEMBL1201082::CHEMBL41::Fluoxetin::Fluoxetine::Prozac::US9120771, Fluoxetine::cid_62857	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30130&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	RFX	4MM8,3GWV	3386	85147891	5118	CHEMBL1201082CHEMBL41	DB00472	203		ZINC01530638	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161251	CN(C)CCCN1c2ccccc2CCc2ccccc12	InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3	BCGWQEUPMDMJNV-UHFFFAOYSA-N	50010859	CHEMBL11::IMIPRAMINE HYDROCHLORIDE::IMIPRAMINE PAMOATE::Imipramin	Alpha-2A adrenergic receptor		 3100								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010859	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010859&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	IXX	2Q72,7LWD,6G9B	3696	103923605	47499	CHEMBL11	DB00458	357	C07049	ZINC00020245	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161252	CN(CCCN1c2ccccc2CCc2ccccc12)CC(=O)c1ccc(Cl)cc1	InChI=1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3	SAPNXPWPAUFAJU-UHFFFAOYSA-N	82437	CAS_23047-25-8::Lofepramine::NSC_3947::US8629135, SW-06	Alpha-2A adrenergic receptor		 2700								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82437&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3947	136350408	47782					ZINC01542929	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161253	CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CCOc1ccccc1	InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3	VRBKIVRKKCLPHA-UHFFFAOYSA-N	50069447	1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one::2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one::CHEMBL623::NEFAZODONE::US9138393, Nefazodone HCl::US9144538, Nefazodone HCl	Alpha-2A adrenergic receptor		 640								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069447&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4449	103963508	7494	CHEMBL623	DB01149	7247	C07256	ZINC00538065	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161254	NCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1	InChI=1S/C16H16F3NO/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12/h1-9,15H,10-11,20H2/t15-/m0/s1	WIQRCHMSJFFONW-HNNXBMFYSA-N	50254790	(S)-Norfluoxetine::CHEMBL465123::NORFLUOXETINE	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254790&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	405	4XDK	3058751	104106938		CHEMBL465123				ZINC00004531	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161255	CNCCC=C1c2ccccc2CCc2ccccc12	InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3	PHVGLTMQBUFIQQ-UHFFFAOYSA-N	112777	NORTRIPTYLINE::US8629135, SW-02	Alpha-2A adrenergic receptor		 2030								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=112777	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=112777&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	21B	4M48	4543	194690518			DB00540		C07274		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161256	Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1	InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1	AHOUBRCZNHFOSL-YOEHRIQHSA-N	22416	(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::CHEMBL490::PAROXETINE::US09969700, Paroxetine::US9944618, Compound ID No. 182::[3H]Paroxetine	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22416&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8PR	6F6I,7OIH,6DZW,6AWN,4JLT,3V5W,4MM4,6VRH,5I6X,4L9I	43815	49846231	7936	CHEMBL490	DB00715	4561	C07415	ZINC00527386	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161257	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 3.6								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161258	CN[C@@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc12	InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17+/m0/s1	VGKDLMBJGBXTGI-YVEFUNNKSA-N	82217	CHEMBL284994::CP-52003::SERTRALINE::[4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-methyl-amine	Alpha-2A adrenergic receptor		 4100								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82217&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9882979	136350189		CHEMBL284994				ZINC03831445	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161259	CNCCC(Oc1ccccc1C)c1ccccc1	InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3	VHGCDTVCOLNTBX-UHFFFAOYSA-N	50022784	(R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine::ATOMOXETINE::CHEMBL641::Methyl-((R)-3-phenyl-3-o-tolyloxy-propyl)-amine::Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine::Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine(tomoxetine)::Strattera::Tomoxetine	Alpha-2A adrenergic receptor		 8800								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022784&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6850813	103933341		CHEMBL641				ZINC02570822	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161260	Clc1cccc(c1)N1CCN(CCCn2nc3ccccn3c2=O)CC1	InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2	PHLBKPHSAVXXEF-UHFFFAOYSA-N	50073444	2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one::CHEMBL621::TRAZODONE	Alpha-2A adrenergic receptor		 320								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5533	103966838	9654	CHEMBL621	DB00656	213	C07156	ZINC00538483	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161261	COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1	InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	PNVNVHUZROJLTJ-UHFFFAOYSA-N	82071	CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/BF02244985	10.7270/Q25X27FZ	7855217			Cusack, B; Nelson, A; Richelson, E	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	VFX	8F4W	5656	131342645			DB00285		C07187	ZINC00896698	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161501	COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1	InChI=1S/C25H30N2O3/c1-25(2)20-9-5-4-8-18(20)23(28)19(24(25)29)12-13-26-14-16-27(17-15-26)21-10-6-7-11-22(21)30-3/h4-11,19H,12-17H2,1-3H3	OSEADGVOKYGIER-UHFFFAOYSA-N	81772	ARC-239::CAS_122211::NSC_122211	Alpha-2A adrenergic receptor		 218.77								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81772&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122211	131342346				524		ZINC60027297	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161505	CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13	InChI=1S/C25H25BrN4/c1-29-14-16(15-30-11-10-27-25(30)17-6-3-2-4-7-17)12-19-18-8-5-9-21-23(18)20(13-22(19)29)24(26)28-21/h2-11,16,19,22,28H,12-15H2,1H3/t16-,19-,22-/m1/s1	VKABNRMTNPWHBD-ZWDAVXSWSA-N	81773	BAM 1303::BAM-1303::CAS_115219-10-8	Alpha-2A adrenergic receptor		 1.34								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81773&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344262	131342347						ZINC38563583	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158851	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2A adrenergic receptor		 750								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158852	CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	ZUXABONWMNSFBN-UHFFFAOYSA-N	22869	6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine	Alpha-2A adrenergic receptor		 160								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	49846683				38		ZINC19796155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158853	CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34	InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	ZZJYIKPMDIWRSN-HWBMXIPRSA-N	50008735	(+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol	Alpha-2A adrenergic receptor		 310								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			37459	103921865		CHEMBL8514		62		ZINC02008410	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158854	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2	PLDUPXSUYLZYBN-UHFFFAOYSA-N	78433	2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17	Alpha-2A adrenergic receptor		 1550								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3372	252655189			DB00623		C07010	ZINC19203912	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158855	OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1	InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	LNEPOXFFQSENCJ-UHFFFAOYSA-N	21398	4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1	Alpha-2A adrenergic receptor		 3800								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	GMJ	6X10,6DJZ,6LUQ	3559	49689470	5613	CHEMBL54CHEMBL545608	DB00502	86	C01814	ZINC00537822	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158856	CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12	InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3	XJGVXQDUIWGIRW-UHFFFAOYSA-N	22871	13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine	Alpha-2A adrenergic receptor		 2400								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3964	49846685	50841	CHEMBL831	DB00408	205	C07104	ZINC19796158	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158857	CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O	InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3	SLVMESMUVMCQIY-UHFFFAOYSA-N	50131440	10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23	Alpha-2A adrenergic receptor		 1600								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131440&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4078	104022598	6780	CHEMBL1088	DB00933	7227	C07143	ZINC03831042	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158858	CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12	InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3	KLPWJLBORRMFGK-UHFFFAOYSA-N	50130290	3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban	Alpha-2A adrenergic receptor		 640								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23897	104021724		CHEMBL460	DB01618	207	C07230	ZINC22002218	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158859	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1	InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2	RGCVKNLCSQQDEP-UHFFFAOYSA-N	50130273	2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine	Alpha-2A adrenergic receptor		 510								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4748	104021707	8028	CHEMBL567	DB00850	209	C07427	ZINC19228902	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158860	CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1	InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3	WIKYUJGCLQQFNW-UHFFFAOYSA-N	78434	2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499	Alpha-2A adrenergic receptor		 1700								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	P77	3M0W	4917	252655190	8435		DB00433		C07403	ZINC19796018	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158861	CN(C)CCCN1c2ccccc2Sc2ccccc12	InChI=1S/C17H20N2S/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19/h3-6,8-11H,7,12-13H2,1-2H3	ZGUGWUXLJSTTMA-UHFFFAOYSA-N	67545	N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride::PROMAZINE::SR-01000000228-4::US9504692, Promazine::cid_5887::dimethyl(3-phenothiazin-10-ylpropyl)amine;hydrochloride	Alpha-2A adrenergic receptor		 900								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67545&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	P2Z	7LGI,4MA7	4926	252645840			DB00420		C07379	ZINC00010402	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158862	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 2.7								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158863	Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1	InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)	DKGZKTPJOSAWFA-UHFFFAOYSA-N	21397	8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265	Alpha-2A adrenergic receptor		 660								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SIP	7DFP	5265	49689469	9233	CHEMBL267930		99		ZINC00643233	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158864	CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1	InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3	KLBQZWRITKRQQV-UHFFFAOYSA-N	50002338	(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine	Alpha-2A adrenergic receptor		 800								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LZU	4I1R,4UHX	5452	103916644	9566	CHEMBL479	DB00679	100		ZINC01530697	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158865	CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1	InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8-	GFBKORZTTCHDGY-UWVJOHFNSA-N	78576	CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene	Alpha-2A adrenergic receptor		 200								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78576&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			941651	252655323			DB01623	212		ZINC30690433	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158866	CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3	ZEWQUBUPAILYHI-UHFFFAOYSA-N	79181	10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566	Alpha-2A adrenergic receptor		 2600								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TFP	4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0	5566	252655893			DB00831		C07168	ZINC19418959	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
158867	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 1.6								PDSP Ki	10.1016/0014-2999(84)90478-3	10.7270/Q2WW7G5B	6149136			Richelson, E; Nelson, A	Mayo Clinic	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161509	CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13	InChI=1S/C25H25BrN4/c1-29-14-16(15-30-11-10-27-25(30)17-6-3-2-4-7-17)12-19-18-8-5-9-21-23(18)20(13-22(19)29)24(26)28-21/h2-11,16,19,22,28H,12-15H2,1H3/t16-,19-,22-/m1/s1	VKABNRMTNPWHBD-ZWDAVXSWSA-N	81773	BAM 1303::BAM-1303::CAS_115219-10-8	Alpha-2A adrenergic receptor		 0.93								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81773&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344262	131342347						ZINC38563583	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161513	NCC(O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2	SFLSHLFXELFNJZ-UHFFFAOYSA-N	35234	DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE	Alpha-2A adrenergic receptor		 15.13								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	951	85753313	33569			484		ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161517	NCC(O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2	SFLSHLFXELFNJZ-UHFFFAOYSA-N	35234	DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE	Alpha-2A adrenergic receptor		 56.23								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	951	85753313	33569			484		ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161521	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 1.44								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161525	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 1.28								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161529	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 316.22								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161533	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 562.34								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161537	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.43								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161541	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.61								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161545	CN1CCc2c(Cl)ccc(OCC=C(C)C)c2CC1	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3	MBYSTKNEMJZSIK-UHFFFAOYSA-N	50030623	6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL114166::SK&F-104078::SK-104078::SKF 104078	Alpha-2A adrenergic receptor		 31.62								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030623&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122295	103939472		CHEMBL114166				ZINC05158824	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161549	CN1CCc2c(Cl)ccc(OCC=C(C)C)c2CC1	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3	MBYSTKNEMJZSIK-UHFFFAOYSA-N	50030623	6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL114166::SK&F-104078::SK-104078::SKF 104078	Alpha-2A adrenergic receptor		 39.81								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030623&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122295	103939472		CHEMBL114166				ZINC05158824	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161553	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2A adrenergic receptor		 8.31								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161557	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2A adrenergic receptor		 9.54								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161561	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2A adrenergic receptor		 1.2								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
161565	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2A adrenergic receptor		 2.18								PDSP Ki		10.7270/Q24X569K	7908054			O'Rourke, MF; Blaxall, HS; Iversen, LJ; Bylund, DB	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162740	CC1N(CC2=NCCN2)Cc2ccccc12	InChI=1S/C13H17N3/c1-10-12-5-3-2-4-11(12)8-16(10)9-13-14-6-7-15-13/h2-5,10H,6-9H2,1H3,(H,14,15)	SGOFAUSEYBZKDQ-UHFFFAOYSA-N	82520	BRL44408::CAS_121850::NSC_121850	Alpha-2A adrenergic receptor		 5.68								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82520	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82520&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			121850	136350490				525		ZINC22067803	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162741	NC(=N)NC(=O)Cc1c(Cl)cccc1Cl	InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)	INJOMKTZOLKMBF-UHFFFAOYSA-N	81984	CAS_29110-47-2::Guanfacine::NSC_3519	Alpha-2A adrenergic receptor		 50.3								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81984&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3519	131342558			DB01018	522	C07037	ZINC03872738	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162742	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 9.68								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162743	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 2250								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162744	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 3.76								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162745	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2A adrenergic receptor		 0.62								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162746	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2A adrenergic receptor		 54.3								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162747	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2A adrenergic receptor		 14.6								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
162748	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 3.71								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172246	CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3	WXPNDRBBWZMPQG-UHFFFAOYSA-N	82479	CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2	Alpha-2A adrenergic receptor		 280								PDSP Ki	10.1016/0893-133X(94)00129-N	10.7270/Q2445K1M	8822531			Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4585	136350450				47		ZINC03873830	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172110	Cn1ccc2cc(NC(=O)Nc3cccnc3)ccc12	InChI=1S/C15H14N4O/c1-19-8-6-11-9-12(4-5-14(11)19)17-15(20)18-13-3-2-7-16-10-13/h2-10H,1H3,(H2,17,18,20)	OJZZJTLBYXHUSJ-UHFFFAOYSA-N	82272	SB 200646::SB200646a	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1016/0166-4328(96)00087-3	10.7270/Q2RX99ND	8788493			Baxter, GS	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82272&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			126769	136350244					C11739	ZINC00005475	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176455	Clc1cccc(Cl)c1N(CC=C)C1=NCCN1	InChI=1S/C12H13Cl2N3/c1-2-8-17(12-15-6-7-16-12)11-9(13)4-3-5-10(11)14/h2-5H,1,6-8H2,(H,15,16)	OXTYVEUAQHPPMV-UHFFFAOYSA-N	85231	Alinidine::CAS_33178-86-8	Alpha-2A adrenergic receptor		 6025.60								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85231&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			36354	136351331						ZINC00003723	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176456	CC(N)C(O)c1ccc(O)c(O)c1	InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3	GEFQWZLICWMTKF-UHFFFAOYSA-N	50027502	4-(2-Amino-1-hydroxy-propyl)-benzene-1,2-diol::Aldoclor-150::Aldoclor-250::CHEMBL764::METHYLNORADRENALINE::alpha-Methyl-(+)norepinephrine,(+/-)::alpha-Methyl-(+/-)norepinephrine,(+/-)::alpha-Methyl-(-)norepinephrine,(+/-)	Alpha-2A adrenergic receptor		 3630.78								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027502&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3917	103936972		CHEMBL764			C17925	ZINC00034160	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176457	Nc1nc2CCN(CC=C)CCc2s1	InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12)	DHSSDEDRBUKTQY-UHFFFAOYSA-N	86053	B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374	Alpha-2A adrenergic receptor		 398.11								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86053&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5374	136352153		CHEMBL279085				ZINC00006644	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176458	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 61.66								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176461	C[C@@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	CUHVIMMYOGQXCV-LLVKDONJSA-N	50241196	(R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole::4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole::CHEMBL397901::Dexmedetomidine	Alpha-2A adrenergic receptor		 13.18								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241196&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60612	104098658		CHEMBL397901		521		ZINC04676236	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176463	CNCC(O)c1ccc(O)c(O)c1	InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3	UCTWMZQNUQWSLP-UHFFFAOYSA-N	84342	4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol::4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, 1::4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride::4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol;hydrochloride::4-[2-(methylamino)-1-oxidanyl-ethyl]benzene-1,2-diol;hydrochloride::DL-ADRENALINE HYDROCHLORIDE::EPINEPHRINE::EPINEPHRINE,(+)::MLS001333244::SMR000058236::cid_5924	Alpha-2A adrenergic receptor		 1479.11								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	ALE	7BTS,4A7U,7BRN,2HKK,4LDO	838	252659436					C02012	ZINC00039090	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176465	NC(N)=NN=Cc1c(Cl)cccc1Cl	InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)	WDZVGELJXXEGPV-UHFFFAOYSA-N	81979	CAS_5051-62-7::CAS_65636::Fluprofylline::Guanabenz::NSC_3517::NSC_65636	Alpha-2A adrenergic receptor		 21.88								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81979&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5702063	131342553			DB00629			ZINC03872735	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176466	NC(=N)NC(=O)Cc1c(Cl)cccc1Cl	InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)	INJOMKTZOLKMBF-UHFFFAOYSA-N	81984	CAS_29110-47-2::Guanfacine::NSC_3519	Alpha-2A adrenergic receptor		 93.33								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81984&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3519	131342558			DB01018	522	C07037	ZINC03872738	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176468	Fc1cccc(Cl)c1C1CN2CCN=C2C1	InChI=1S/C12H12ClFN2/c13-9-2-1-3-10(14)12(9)8-6-11-15-4-5-16(11)7-8/h1-3,8H,4-7H2	VDDKWLCHDOJXJM-UHFFFAOYSA-N	85232	CAS_67249-51-8::ICI 106270	Alpha-2A adrenergic receptor		 7.94								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85232&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			128761	136351332						ZINC06091692	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176469	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2A adrenergic receptor		 9.77								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176470	CCn1ccnc1CC1COc2ccccc2O1	InChI=1S/C14H16N2O2/c1-2-16-8-7-15-14(16)9-11-10-17-12-5-3-4-6-13(12)18-11/h3-8,11H,2,9-10H2,1H3	UXABARREKCJULM-UHFFFAOYSA-N	85234	CAS_81167-16-0::IMILOXAN::NSC_133621	Alpha-2A adrenergic receptor		 316.23								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85234&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133621	136351334				3470		ZINC03995466	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176472	C[C@@H](Oc1c(Cl)cccc1Cl)C1=NCCN1	InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)	KSMAGQUYOIHWFS-UHFFFAOYSA-N	85233	CAS_81447-78-1::Levlofexidine	Alpha-2A adrenergic receptor		 14.45								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85233	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85233&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038503	136351333	51368					ZINC00005626	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176473	CN1CCC2(CCN3CCc4c(oc5ccccc45)C3C2)N(C)C1=O	InChI=1S/C20H25N3O2/c1-21-11-8-20(22(2)19(21)24)9-12-23-10-7-15-14-5-3-4-6-17(14)25-18(15)16(23)13-20/h3-6,16H,7-13H2,1-2H3	JRDUBBHIPPPSLP-UHFFFAOYSA-N	81811	CAS_123679::L-657,743::MK-912::NSC_123679	Alpha-2A adrenergic receptor		 0.85								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81811&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			123679	131342385						ZINC04475284	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176474	C(C1=NCCN1)c1cccc2ccccc12	InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)	CNIIGCLFLJGOGP-UHFFFAOYSA-N	50001922	2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; hydrochloride::Albalon::CHEMBL1706::NAPHAZOLINE HYDROCHLORIDE::Nafazair::Naphazoline::Naphazoline Nitrate::Naphcon forte::Opcon::Vasocon::cid_11079	Alpha-2A adrenergic receptor		 20.89								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001922&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4436	103916289		CHEMBL1706	DB06711		C07898	ZINC00119717	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176477	c1ccc2ccccc2c1	InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H	UFWIBTONFRDIAS-UHFFFAOYSA-N	50159249	CHEMBL16293::Naphthalen::Naphthalin::naftaleno::naftalina::naphtalene::naphtaline::naphthalene	Alpha-2A adrenergic receptor		 4.57								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159249&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPY	7PN4,5VKF,6EKW,1O7G	931	104045832	16482	CHEMBL16293			C00829	ZINC00967522	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176480	NCC(O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2	SFLSHLFXELFNJZ-UHFFFAOYSA-N	35234	DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE	Alpha-2A adrenergic receptor		 1995.26								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	951	85753313	33569			484		ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176482	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 7.24								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176485	Nc1cc(Cl)c(NC2=NCCN2)c(Cl)c1	InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15)	IEJXVRYNEISIKR-UHFFFAOYSA-N	81926	Aminoclonidine, p::CAS_66711-21-5::NSC_51763::p-AMINOCLONIDINE	Alpha-2A adrenergic receptor		 7.94								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81926&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2216	131342500	2789		DB00964		C07668	ZINC00057175	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176486	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 20.42								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176487	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 794.33								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176488	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 1.20								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176490	C1CC1C(NC1=[NH+]CCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)/p+1	CQXADFVORZEARL-UHFFFAOYSA-O	50262235	rilmenidine	Alpha-2A adrenergic receptor		 1584.89								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262235&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44577959	104110975					C11120	ZINC00009708	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176492	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2A adrenergic receptor		 0.36								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176494	CCc1cccc(CC)c1N=C1NCCN1	InChI=1S/C13H19N3/c1-3-10-6-5-7-11(4-2)12(10)16-13-14-8-9-15-13/h5-7H,3-4,8-9H2,1-2H3,(H2,14,15,16)	IALHTUPVRAQZFI-UHFFFAOYSA-N	85235	CAS_4749-61-5::ST 91::ST-91	Alpha-2A adrenergic receptor		 575.44								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85235&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			20864	136351335						ZINC02037627	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176496	C(C1=NCCN1)c1ccccc1	InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12)	JIVZKJJQOZQXQB-UHFFFAOYSA-N	55436	2-(phenylmethyl)-4,5-dihydro-1H-imidazole;hydrochloride::2-Benzyl-4,5-dihydro-1H-imidazole::2-benzyl-2-imidazoline;hydrochloride::2-benzyl-4,5-dihydro-1H-imidazole;hydrochloride::MLS000559484::SMR000149600::Tolazoline::cid_6048	Alpha-2A adrenergic receptor		 229.09								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55436&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5504	252635433	28502		DB00797		C07147	ZINC00125006	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176497	C1CNC(N1)=Nc1cccc2CCCCc12	InChI=1S/C13H17N3/c1-2-6-11-10(4-1)5-3-7-12(11)16-13-14-8-9-15-13/h3,5,7H,1-2,4,6,8-9H2,(H2,14,15,16)	QQJLHRRUATVHED-UHFFFAOYSA-N	50027056	(4,5-Dihydro-1H-imidazol-2-yl)-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine::CHEMBL32573::Imidazolidin-2-ylidene-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine::Tramazoline	Alpha-2A adrenergic receptor		 31.62								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027056&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5524	103936638		CHEMBL32573				ZINC01534528	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176499	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2A adrenergic receptor		 213.80								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176501	Cc1cccc(C)c1N=C1NCCCS1	InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)	BPICBUSOMSTKRF-UHFFFAOYSA-N	50027069	(2,6-Dimethyl-phenyl)-[1,3]thiazinan-2-ylidene-amine::(5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-dimethyl-phenyl)-amine::CHEMBL297362::Xylazine	Alpha-2A adrenergic receptor		 5754.40								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027069	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027069&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5707	103936651		CHEMBL297362		523		ZINC00002248	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
176503	Cc1cc(cc(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)	HUCJFAOMUPXHDK-UHFFFAOYSA-N	30703	2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline;hydrochloride::2-[(4-tert-butyl-2,6-dimethyl-phenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride::2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride::CHEMBL312448::MLS000069695::SMR000058526::XYLOMETAZOLINE HYDROCHLORIDE::Xylometazoline::cid_5282386	Alpha-2A adrenergic receptor		 15.14								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30703&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5709	252614962		CHEMBL312448	DB06694		C07913	ZINC00057534	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175337	CN(C)CCC=C1c2ccccc2CCc2ccccc12	InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3	KRMDCWKBEZIMAB-UHFFFAOYSA-N	50020712	10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene::10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine::3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine::3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine::3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine::5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene::5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene::5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene::AMITRIPTYLINE::Amitriptylin::CHEMBL629	Alpha-2A adrenergic receptor	Homo sapiens	 114								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TP0    	8Y93,5HA9,3APV	2160	103931468	2666	CHEMBL629	DB00321	200	C06824	ZINC00968257	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175338	CNCCCN1c2ccccc2CCc2ccccc12	InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3	HCYAFALTSJYZDH-UHFFFAOYSA-N	35229	3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine::5-(gamma-methylaminopropyl)iminodibenzyl::CHEMBL72::DESIPRAMINE HYDROCHLORIDE::DMI::Desipramin::Desipramine::Desmethylimipramine::N-(3-methylaminopropyl)iminobibenzyl::US9944618, Compound ID No. 174::demethylimipramine::monodemethylimipramine::norimipramine	Alpha-2A adrenergic receptor		 1379								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35229&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	DSM	7Q19,2QJU,7Q2N,7Q2O,7Q2P,2QB4	2995	85753308	47781	CHEMBL72	DB01151	2399	C06943	ZINC01530611	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175339	CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1	InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3	RTHCYVBBDHJXIQ-UHFFFAOYSA-N	30130	CHEMBL1201082::CHEMBL41::Fluoxetin::Fluoxetine::Prozac::US9120771, Fluoxetine::cid_62857	Alpha-2A adrenergic receptor		 3090								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30130&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	RFX	4MM8,3GWV	3386	85147891	5118	CHEMBL1201082CHEMBL41	DB00472	203		ZINC01530638	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175340	CC(O)c1nn(CCCN2CCN(CC2)c2ccc(Cl)cc2)c(=O)n1CCOc1ccccc1	InChI=1S/C25H32ClN5O3/c1-20(32)24-27-31(25(33)30(24)18-19-34-23-6-3-2-4-7-23)13-5-12-28-14-16-29(17-15-28)22-10-8-21(26)9-11-22/h2-4,6-11,20,32H,5,12-19H2,1H3	PPJRQXMDFSRWFH-UHFFFAOYSA-N	85198	CAS_127096::Hydroxynefazodone::NSC_127096	Alpha-2A adrenergic receptor		 63								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85198&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127096	136351298						ZINC14952264	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175341	Clc1cccc(c1)N1CCNCC1	InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2	VHFVKMTVMIZMIK-UHFFFAOYSA-N	50001915	1-(3-chlorophenyl)piperazine::CHEMBL478::m-Chlorophenylpiperazine::mCPP	Alpha-2A adrenergic receptor		 112								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001915	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001915&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1355	103916282	10588	CHEMBL478		142	C11738	ZINC00004285	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175342	CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CCOc1ccccc1	InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3	VRBKIVRKKCLPHA-UHFFFAOYSA-N	50069447	1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one::2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one::CHEMBL623::NEFAZODONE::US9138393, Nefazodone HCl::US9144538, Nefazodone HCl	Alpha-2A adrenergic receptor		 84								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069447&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4449	103963508	7494	CHEMBL623	DB01149	7247	C07256	ZINC00538065	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175343	Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1	InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1	AHOUBRCZNHFOSL-YOEHRIQHSA-N	22416	(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::CHEMBL490::PAROXETINE::US09969700, Paroxetine::US9944618, Compound ID No. 182::[3H]Paroxetine	Alpha-2A adrenergic receptor		 3915								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22416&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8PR	6F6I,7OIH,6DZW,6AWN,4JLT,3V5W,4MM4,6VRH,5I6X,4L9I	43815	49846231	7936	CHEMBL490	DB00715	4561	C07415	ZINC00527386	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175344	CN[C@@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc12	InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17+/m0/s1	VGKDLMBJGBXTGI-YVEFUNNKSA-N	82217	CHEMBL284994::CP-52003::SERTRALINE::[4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-methyl-amine	Alpha-2A adrenergic receptor		 477								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82217&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9882979	136350189		CHEMBL284994				ZINC03831445	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175345	Clc1cccc(c1)N1CCN(CCCn2nc3ccccn3c2=O)CC1	InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2	PHLBKPHSAVXXEF-UHFFFAOYSA-N	50073444	2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one::CHEMBL621::TRAZODONE	Alpha-2A adrenergic receptor		 106								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5533	103966838	9654	CHEMBL621	DB00656	213	C07156	ZINC00538483	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175346	Clc1cccc(c1)N1CCN(CCCn2[nH]c(=O)n(CCOc3ccccc3)c2=O)CC1	InChI=1S/C23H28ClN5O3/c24-19-6-4-7-20(18-19)27-14-12-26(13-15-27)10-5-11-29-23(31)28(22(30)25-29)16-17-32-21-8-2-1-3-9-21/h1-4,6-9,18H,5,10-17H2,(H,25,30)	BTNXVMLCKOPOEP-UHFFFAOYSA-N	85197	Triazoledione	Alpha-2A adrenergic receptor		 1915								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85197&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9804174	136351297						ZINC40683529	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175347	COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1	InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	PNVNVHUZROJLTJ-UHFFFAOYSA-N	82071	CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655	Alpha-2A adrenergic receptor		>10000								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	VFX	8F4W	5656	131342645			DB00285		C07187	ZINC00896698	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175348	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.71								PDSP Ki		10.7270/Q25Q4TMX	9400006			Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172896	Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3	PMXMIIMHBWHSKN-UHFFFAOYSA-N	50252513	3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE	Alpha-2A adrenergic receptor		 30								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	K4I		115237	104105311		CHEMBL1621	DB01267	7258		ZINC04214700	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172897	CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	ZUXABONWMNSFBN-UHFFFAOYSA-N	22869	6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine	Alpha-2A adrenergic receptor		 50								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	49846683				38		ZINC19796155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172898	Fc1ccc(cc1)C(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1	InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35)	QOYHHIBFXOOADH-UHFFFAOYSA-N	26948	8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL46516::FLUSPIRILENE::NCGC00015424::cid_3396::med.21724, Compound Fluspirilene::spiropiperidine analogue, 1	Alpha-2A adrenergic receptor		 570								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26948&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3396	57298659		CHEMBL46516	DB04842	85		ZINC00537755	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172899	OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1	InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	LNEPOXFFQSENCJ-UHFFFAOYSA-N	21398	4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1	Alpha-2A adrenergic receptor		 1130								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	GMJ	6X10,6DJZ,6LUQ	3559	49689470	5613	CHEMBL54CHEMBL545608	DB00502	86	C01814	ZINC00537822	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172900	CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3	WXPNDRBBWZMPQG-UHFFFAOYSA-N	82479	CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2	Alpha-2A adrenergic receptor		 470								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4585	136350450				47		ZINC03873830	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172901	CN1CC2C(C1)c1cc(Cl)ccc1Oc1ccccc21	InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3	VSWBSWWIRNCQIJ-UHFFFAOYSA-N	84994	CAS_163091::NSC_163091::ORG-5222	Alpha-2A adrenergic receptor		 6.5								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84994&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9903970	136351094	71255		DB06216			ZINC11677376	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172902	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 1.3								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172903	NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1	InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27)	AXKPFOAXAHJUAG-UHFFFAOYSA-N	81483	CAS_1893-33-0::NSC_4830::PIPAMPERONE	Alpha-2A adrenergic receptor		 860								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81483&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4830	131342057			DB09286	92		ZINC21297287	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172904	OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12	InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2	URKOMYMAXPYINW-UHFFFAOYSA-N	50095890	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE	Alpha-2A adrenergic receptor		 2230								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5002	103993497	8707	CHEMBL716	DB01224	50	C07397	ZINC19632628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172905	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone	Alpha-2A adrenergic receptor		 23								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252	8871	CHEMBL85	DB00734	96		ZINC00538312	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172906	Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12	InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	GZKLJWGUPQBVJQ-UHFFFAOYSA-N	50001786	1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole	Alpha-2A adrenergic receptor		 640								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60149	103916159	9122	CHEMBL12713	DB06144	98	C07567	ZINC00538337	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172907	Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12	InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	MVWVFYHBGMAFLY-UHFFFAOYSA-N	50048803	5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE	Alpha-2A adrenergic receptor		 160								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60854	103979184	10119	CHEMBL708	DB00246	59	C07568	ZINC00538550	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
172908	CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3	HDOZVRUNCMBHFH-UHFFFAOYSA-N	35255	2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine	Alpha-2A adrenergic receptor		 180								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZOT	6A94	5736	85753334	32316	CHEMBL285802	DB09225	103		ZINC00002264	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
175722	Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2[C@@]3(C)CCC(C3)C2(C)C)cc1	InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22?,27?,29-/m0/s1	SUGVYNSRNKFXQM-ACSDJOOWSA-N	21280	5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl]-1H-pyrazole-3-carboxamide::N-(1,3,3-trimethylbicyclo(2.2.1)heptan-2-yl)-5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)pyrazole-3-carboxamide::SR 144528::SR-144528::SR144528	Alpha-2A adrenergic receptor		>10000								PDSP Ki		10.7270/Q2D50KHT	9454810			Rinaldi-Carmona, M; Barth, F; Millan, J; Derocq, JM; Casellas, P; Congy, C; Oustric, D; Sarran, M; Bouaboula, M; Calandra, B; Portier, M; Shire, D; Breliere, JC; Le Fur, GL	Sanofi Recherche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21280&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			21310426	49689352						ZINC03952700	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182152	COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12	InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)	ZPMNHBXQOOVQJL-UHFFFAOYSA-N	50122872	4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide::CHEMBL117287::PRUCALOPRIDE::US9663465, prucalopride	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1016/s0014-2999(01)01087-1	10.7270/Q23T9FSX	11438309			Briejer, MR; Bosmans, JP; Van Daele, P; Jurzak, M; Heylen, L; Leysen, JE; Prins, NH; Schuurkes, JA	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122872&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3052762	104015490		CHEMBL117287	DB06480	243		ZINC01891034	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182272	CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1	InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3	WSEQXVZVJXJVFP-UHFFFAOYSA-N	25870	1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile::CHEMBL549::CITALOPRAM::CITALOPRAM HYDROBROMIDE::Escitalopram::[3H]Citalopram::[3H]Cytalopram::[3H]Escitalopram::[3H]Lexapro	Alpha-2A adrenergic receptor		>10000								PDSP Ki		10.7270/Q2QJ7FVW	11454918			Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25870&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	68P	5I73,5I71,5I75	2771	56413158	3723	CHEMBL549	DB00215	4621	C07572	ZINC03800706	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182273	CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12	InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3	GDLIGKIOYRNHDA-UHFFFAOYSA-N	77970	3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-1-propanamine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-dimethyl-amine;hydrochloride::CHLORIMIPRAMINE::CLOMIPRAMINE::CLOMIPRAMINE HYDROCHLORIDE::CLOMIPRIMINE::MLS000028511::SMR000058295::cid_68539::med.21724, Compound Clomipramine	Alpha-2A adrenergic receptor		 525								PDSP Ki		10.7270/Q2QJ7FVW	11454918			Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77970	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77970&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CXX	4MMA,2QEI,6G9I,2Q6H	2801	252654733	3755		DB01242		C06918		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182274	CCOc1ccccc1O[C@H]([C@@H]1CNCCO1)c1ccccc1	InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19-/m0/s1	CBQGYUDMJHNJBX-OALUTQOASA-N	35226	(S,S)-reboxetine::Reboxetine::Vestra	Alpha-2A adrenergic receptor		>10000								PDSP Ki		10.7270/Q2QJ7FVW	11454918			Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35226&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			65856	85753305			DB00234	4808		ZINC00006923	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182275	COc1ccc2CC(CN(C)C)(c2c1)C1(O)CCCCC1	InChI=1S/C18H27NO2/c1-19(2)13-17(18(20)9-5-4-6-10-18)12-14-7-8-15(21-3)11-16(14)17/h7-8,11,20H,4-6,9-10,12-13H2,1-3H3	UBIQMAFTTDZGEX-UHFFFAOYSA-N	85805	S33005	Alpha-2A adrenergic receptor		>10000								PDSP Ki		10.7270/Q2QJ7FVW	11454918			Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85805&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9925999	136351905						ZINC13914237	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182276	COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1	InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	PNVNVHUZROJLTJ-UHFFFAOYSA-N	82071	CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655	Alpha-2A adrenergic receptor		>10000								PDSP Ki		10.7270/Q2QJ7FVW	11454918			Millan, MJ; Gobert, A; Lejeune, F; Newman-Tancredi, A; Rivet, JM; Auclair, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	VFX	8F4W	5656	131342645			DB00285		C07187	ZINC00896698	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182405	CC(CF)NCC(O)COc1cccc2[nH]c3ccccc3c12	InChI=1S/C18H21FN2O2/c1-12(9-19)20-10-13(22)11-23-17-8-4-7-16-18(17)14-5-2-3-6-15(14)21-16/h2-8,12-13,20-22H,9-11H2,1H3	QHLGXPUIUKSADT-UHFFFAOYSA-N	85818	Fluorocarazolol,(R)::Fluorocarazolol,(S)	Alpha-2A adrenergic receptor		 3360								PDSP Ki	10.1007/s002130100844	10.7270/Q22V2DPJ	11512051			Roth, BL; Ernsberger, P; Steinberg, SA; Rao, S; Rauser, L; Savage, J; Hufeisen, S; Berridge, MS; Muzic, RF	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85818&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133038	136351918						ZINC06036510	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182406	CC(CF)NCC(O)COc1cccc2[nH]c3ccccc3c12	InChI=1S/C18H21FN2O2/c1-12(9-19)20-10-13(22)11-23-17-8-4-7-16-18(17)14-5-2-3-6-15(14)21-16/h2-8,12-13,20-22H,9-11H2,1H3	QHLGXPUIUKSADT-UHFFFAOYSA-N	85818	Fluorocarazolol,(R)::Fluorocarazolol,(S)	Alpha-2A adrenergic receptor		 2870								PDSP Ki	10.1007/s002130100844	10.7270/Q22V2DPJ	11512051			Roth, BL; Ernsberger, P; Steinberg, SA; Rao, S; Rauser, L; Savage, J; Hufeisen, S; Berridge, MS; Muzic, RF	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85818&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133038	136351918						ZINC06036510	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180031	Fc1cccc2OC3CNCC3Oc12	InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2	XSOUHEXVEOQRKJ-UHFFFAOYSA-N	85595	CAS_105182-45-4::Fluparoxan::NSC_72036	Alpha-2A adrenergic receptor		 7.94								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85595&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10219795	136351695				41		ZINC11680328	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180033	Fc1cccc2OC3CNCC3Oc12	InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2	XSOUHEXVEOQRKJ-UHFFFAOYSA-N	85595	CAS_105182-45-4::Fluparoxan::NSC_72036	Alpha-2A adrenergic receptor		 6.3								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85595&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10219795	136351695				41		ZINC11680328	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180034	Fc1cccc2OC3CNCC3Oc12	InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2	XSOUHEXVEOQRKJ-UHFFFAOYSA-N	85595	CAS_105182-45-4::Fluparoxan::NSC_72036	Alpha-2A adrenergic receptor		 7.94								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85595&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10219795	136351695				41		ZINC11680328	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180036	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 1.58								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180037	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 19.95								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180038	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2A adrenergic receptor		 1								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180039	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 7.94								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180041	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 6.3								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
180042	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 3.16								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181291	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 35.4813								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181292	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 50.1187								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181293	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 31.6228								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181295	C[C@@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	CUHVIMMYOGQXCV-LLVKDONJSA-N	50241196	(R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole::4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole::CHEMBL397901::Dexmedetomidine	Alpha-2A adrenergic receptor		 2.0417								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241196&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60612	104098658		CHEMBL397901		521		ZINC04676236	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181296	C[C@@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	CUHVIMMYOGQXCV-LLVKDONJSA-N	50241196	(R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole::4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole::CHEMBL397901::Dexmedetomidine	Alpha-2A adrenergic receptor		 15.8489								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241196&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60612	104098658		CHEMBL397901		521		ZINC04676236	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181297	C[C@@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	CUHVIMMYOGQXCV-LLVKDONJSA-N	50241196	(R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole::4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole::CHEMBL397901::Dexmedetomidine	Alpha-2A adrenergic receptor		 3.1623								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241196&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60612	104098658		CHEMBL397901		521		ZINC04676236	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181298	NCC(O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2	SFLSHLFXELFNJZ-UHFFFAOYSA-N	35234	DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE	Alpha-2A adrenergic receptor		 398.1072								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	951	85753313	33569			484		ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181299	NC1=NC2(CO1)CCc1ccccc1C2	InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14)	ZFZUYTCCHMWWTD-UHFFFAOYSA-N	85709	S18616	Alpha-2A adrenergic receptor		 0.5623								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85709&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10442840	136351809						ZINC13743776	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181300	NC1=NC2(CO1)CCc1ccccc1C2	InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14)	ZFZUYTCCHMWWTD-UHFFFAOYSA-N	85709	S18616	Alpha-2A adrenergic receptor		 0.631								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85709&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10442840	136351809						ZINC13743776	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181301	NC1=NC2(CO1)CCc1ccccc1C2	InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14)	ZFZUYTCCHMWWTD-UHFFFAOYSA-N	85709	S18616	Alpha-2A adrenergic receptor		 0.3162								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85709&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10442840	136351809						ZINC13743776	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181594	Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3	PMXMIIMHBWHSKN-UHFFFAOYSA-N	50252513	3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE	Alpha-2A adrenergic receptor		 80								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	K4I		115237	104105311		CHEMBL1621	DB01267	7258		ZINC04214700	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181595	CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	ZUXABONWMNSFBN-UHFFFAOYSA-N	22869	6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine	Alpha-2A adrenergic receptor		 15								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	49846683				38		ZINC19796155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181596	OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1	InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	LNEPOXFFQSENCJ-UHFFFAOYSA-N	21398	4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1	Alpha-2A adrenergic receptor		 600								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	GMJ	6X10,6DJZ,6LUQ	3559	49689470	5613	CHEMBL54CHEMBL545608	DB00502	86	C01814	ZINC00537822	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181597	COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O	InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3	XMXHEBAFVSFQEX-UHFFFAOYSA-N	50034043	1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE	Alpha-2A adrenergic receptor		 3								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71360	103942259	65173	CHEMBL14376	DB04946	87		ZINC01548097	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181598	CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1	InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3	DKMFBWQBDIGMHM-UHFFFAOYSA-N	81771	CAS_3575-80-2::MELPERONE::NSC_15387	Alpha-2A adrenergic receptor		 150								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81771	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81771&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			15387	131342345			DB09224			ZINC00001672	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181599	CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3	WXPNDRBBWZMPQG-UHFFFAOYSA-N	82479	CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2	Alpha-2A adrenergic receptor		 280								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4585	136350450				47		ZINC03873830	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181600	CN1CC2C(C1)c1cc(Cl)ccc1Oc1ccccc21	InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3	VSWBSWWIRNCQIJ-UHFFFAOYSA-N	84994	CAS_163091::NSC_163091::ORG-5222	Alpha-2A adrenergic receptor		 16								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84994&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9903970	136351094	71255		DB06216			ZINC11677376	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181601	Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1	InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)	YVUQSNJEYSNKRX-UHFFFAOYSA-N	50334150	1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238	Alpha-2A adrenergic receptor		 650								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	1II	7WLL	16362	125084252	8212	CHEMBL1423	DB01100	90	C07566	ZINC19796084	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181602	OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12	InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2	URKOMYMAXPYINW-UHFFFAOYSA-N	50095890	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE	Alpha-2A adrenergic receptor		 80								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5002	103993497	8707	CHEMBL716	DB01224	50	C07397	ZINC19632628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181603	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 2.5								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181604	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone	Alpha-2A adrenergic receptor		 8								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252	8871	CHEMBL85	DB00734	96		ZINC00538312	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181605	Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12	InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	GZKLJWGUPQBVJQ-UHFFFAOYSA-N	50001786	1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole	Alpha-2A adrenergic receptor		 190								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60149	103916159	9122	CHEMBL12713	DB06144	98	C07567	ZINC00538337	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181606	Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12	InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	MVWVFYHBGMAFLY-UHFFFAOYSA-N	50048803	5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE	Alpha-2A adrenergic receptor		 154								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60854	103979184	10119	CHEMBL708	DB00246	59	C07568	ZINC00538550	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
181607	CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3	HDOZVRUNCMBHFH-UHFFFAOYSA-N	35255	2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine	Alpha-2A adrenergic receptor		 180								PDSP Ki	10.1016/s0024-3205(00)00911-5	10.7270/Q2057DHP	11132243			Richelson, E; Souder, T	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZOT	6A94	5736	85753334	32316	CHEMBL285802	DB09225	103		ZINC00002264	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182021	C(N1CCN(CC1)c1ncccn1)c1ccc2OCOc2c1	InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2	OQDPVLVUJFGPGQ-UHFFFAOYSA-N	85092	CAS_3605-01-4::NSC_4850::Piribedil	Alpha-2A adrenergic receptor		 89.13								PDSP Ki		10.7270/Q2W957RF	11356907			Millan, MJ; Cussac, D; Milligan, G; Carr, C; Audinot, V; Gobert, A; Lejeune, F; Rivet, JM; Brocco, M; Duqueyroix, D; Nicolas, JP; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85092	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85092&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4850	136351192						ZINC19537374	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182064	COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1	InChI=1S/C25H30N2O3/c1-25(2)20-9-5-4-8-18(20)23(28)19(24(25)29)12-13-26-14-16-27(17-15-26)21-10-6-7-11-22(21)30-3/h4-11,19H,12-17H2,1-3H3	OSEADGVOKYGIER-UHFFFAOYSA-N	81772	ARC-239::CAS_122211::NSC_122211	Alpha-2A adrenergic receptor		 373								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81772&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122211	131342346				524		ZINC60027297	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182065	CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13	InChI=1S/C25H25BrN4/c1-29-14-16(15-30-11-10-27-25(30)17-6-3-2-4-7-17)12-19-18-8-5-9-21-23(18)20(13-22(19)29)24(26)28-21/h2-11,16,19,22,28H,12-15H2,1H3/t16-,19-,22-/m1/s1	VKABNRMTNPWHBD-ZWDAVXSWSA-N	81773	BAM 1303::BAM-1303::CAS_115219-10-8	Alpha-2A adrenergic receptor		 18.1								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81773&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344262	131342347						ZINC38563583	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182066	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2A adrenergic receptor		 558								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182067	NCC(O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2	SFLSHLFXELFNJZ-UHFFFAOYSA-N	35234	DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE	Alpha-2A adrenergic receptor		 996								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	951	85753313	33569			484		ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182068	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 4.9								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182069	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 2.6								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182070	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 2133								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182071	COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3	GRTOGORTSDXSFK-UHFFFAOYSA-N	30993	Ajmalicine::MLS000111555::Raubasine::SMR000107477::cid_251561	Alpha-2A adrenergic receptor		 47.6								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30993&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	AJN	4WNT	251561	242052838							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182072	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 3.5								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182073	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2A adrenergic receptor		 0.92								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182074	CN1CCc2c(Cl)ccc(OCC=C(C)C)c2CC1	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3	MBYSTKNEMJZSIK-UHFFFAOYSA-N	50030623	6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL114166::SK&F-104078::SK-104078::SKF 104078	Alpha-2A adrenergic receptor		 30.4								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030623&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122295	103939472		CHEMBL114166				ZINC05158824	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182075	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2A adrenergic receptor		 28.3								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182076	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2A adrenergic receptor		 3.5								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182077	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 1.6								PDSP Ki		10.7270/Q2MS3R9D	11408545			Naselsky, DP; Ashton, D; Ruffolo, RR; Hieble, JP	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184720	CNCCC(Oc1ccccc1C)c1ccccc1	InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3	VHGCDTVCOLNTBX-UHFFFAOYSA-N	50022784	(R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine::ATOMOXETINE::CHEMBL641::Methyl-((R)-3-phenyl-3-o-tolyloxy-propyl)-amine::Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine::Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine(tomoxetine)::Strattera::Tomoxetine	Alpha-2A adrenergic receptor		 1000								PDSP Ki	10.1016/S0893-133X(02)00346-9	10.7270/Q2GQ6W98	12431845			Bymaster, FP; Katner, JS; Nelson, DL; Hemrick-Luecke, SK; Threlkeld, PG; Heiligenstein, JH; Morin, SM; Gehlert, DR; Perry, KW	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022784&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6850813	103933341		CHEMBL641				ZINC02570822	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183706	Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1	InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H	QYDURWHTEIUTEI-UHFFFAOYSA-N	50129952	2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one::8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one::Amentoflavone::CHEMBL63354::cid_5281600	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129952	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129952&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5281600	104021411	2631	CHEMBL63354				ZINC03984030	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183707	CC(C)C(=O)[C@]12C(=O)C(CC=C(C)C)C(=O)[C@@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C2=O	InChI=1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-28H,12,16-17,19-21H2,1-11H3/t27-,28?,33+,34+,35+/m0/s1	GQRREYKSPJMLAW-CWRBZUMDSA-N	50242259	CHEMBL516641::HYPERFORIN	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242259&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91935559	104099004		CHEMBL516641					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183708	Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O	InChI=1S/C30H16O9/c1-7-2-9(32)19-23-15(7)16-8(6-31)3-10(33)20-24(16)28-26-18(12(35)5-14(37)22(26)30(20)39)17-11(34)4-13(36)21(29(19)38)25(17)27(23)28/h2-5,31-37H,6H2,1H3	YXBUQQDFTYOHQI-UHFFFAOYSA-N	50333880	CHEMBL1614664::Hypericin::Pseudohypericin	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50333880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50333880&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5281751	125083982		CHEMBL1614664			C10392	ZINC03917574	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183709	OCC1OC(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C(O)C1O	InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-25,27-30H,6H2	DPFYPHSPTUZJJT-UHFFFAOYSA-N	86036	CAS_5318390::CAS_97331::Hyperoside::Miquelianin::NSC_5318390::NSC_97331	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86036&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5378597	136352136						ZINC05004613	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183710	OCC1OC(O)C(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C1O	InChI=1S/C21H20O12/c22-6-13-15(27)17(29)20(21(30)32-13)33-19-16(28)14-11(26)4-8(23)5-12(14)31-18(19)7-1-2-9(24)10(25)3-7/h1-5,13,15,17,20-25,27-30H,6H2	JDCKEYDYTNBCCS-UHFFFAOYSA-N	84979	Isoquercitrin	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84979&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57339948	136351079						ZINC86865007	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183711	OCC1OC(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C(O)C1O	InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-25,27-30H,6H2	DPFYPHSPTUZJJT-UHFFFAOYSA-N	86036	CAS_5318390::CAS_97331::Hyperoside::Miquelianin::NSC_5318390::NSC_97331	Alpha-2A adrenergic receptor		 716.5								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86036&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5378597	136352136						ZINC05004613	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183712	Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O	InChI=1S/C30H16O9/c1-7-2-9(32)19-23-15(7)16-8(6-31)3-10(33)20-24(16)28-26-18(12(35)5-14(37)22(26)30(20)39)17-11(34)4-13(36)21(29(19)38)25(17)27(23)28/h2-5,31-37H,6H2,1H3	YXBUQQDFTYOHQI-UHFFFAOYSA-N	50333880	CHEMBL1614664::Hypericin::Pseudohypericin	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50333880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50333880&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5281751	125083982		CHEMBL1614664			C10392	ZINC03917574	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183713	Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O	InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H	REFJWTPEDVJJIY-UHFFFAOYSA-N	7460	2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate::CHEMBL50::Quercetin::Quercetin (10)::Quercetin (21)::Quercetin (Qur)::US11021454, Compound Quercetin::US9180183, Quercetin::med.21724, Compound 4	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7460&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	QUE	3BPT,2HCK,3LJ0,4LMU,5FLI,5FLJ,3CF8,4DFU,4MRA,4WNJ,2O3P,2MS6,5AUW,3BXX,6M89,3LM5,1GP6,6AWS,6QCN,6QCD,7VUM,6B1D,2N6C,1E8W,2C9Z,5XG4,5A4V,2UXH,1H1I,2JJ2,6TTA,6IJD,3NVY	5280343	11108251	16243	CHEMBL50	DB04216	5346	C00389	ZINC03869685	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183714	C[C@@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O	InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-24,26-29H,1H3/t7-,15-,17+,18+,21-/m0/s1	XHIUPRGKXRAZCR-HQBVPOQASA-N	84978	Quercitrin::cid_5280459	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84978	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84978&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5280459	136351078	17558				C02757	ZINC04175638	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
183715	C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(O)c4c(cc(O)cc4=O)oc3-c3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O	InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-30,32-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1	HRFGZDXDXWODFE-NVPNHPEKSA-N	50217942	2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside::3-Rhamnoglucosylquercetin::3-Rutinosyl quercetin::CHEMBL226335::cid_5280805::rutin	Alpha-2A adrenergic receptor		 9340								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217942&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	RUT	1RY8	5280805	104091802	28527	CHEMBL226335			C02757	ZINC04096846	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184866	COc1ccc2ccccc2c1CCCCN1CCN(C[C@@H](N2CCN(CC2)C(C)C)c2ccc(F)cc2)CC1	InChI=1S/C34H47FN4O/c1-27(2)38-22-24-39(25-23-38)33(29-11-14-30(35)15-12-29)26-37-20-18-36(19-21-37)17-7-6-10-32-31-9-5-4-8-28(31)13-16-34(32)40-3/h4-5,8-9,11-16,27,33H,6-7,10,17-26H2,1-3H3/t33-/m1/s1	SLGLZEJKMBCODK-MGBGTMOVSA-N	86058	MCL0129	Alpha-2A adrenergic receptor		 1000								PDSP Ki	10.1124/jpet.102.044826	10.7270/Q2FQ9V5W	12538838			Chaki, S; Hirota, S; Funakoshi, T; Suzuki, Y; Suetake, S; Okubo, T; Ishii, T; Nakazato, A; Okuyama, S	Taisho Pharmaceutical Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86058&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6918688	136352158						ZINC22453554	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184900	CCn1c2nocc2c(=O)[nH]c1=O	InChI=1S/C7H7N3O3/c1-2-10-5-4(3-13-9-5)6(11)8-7(10)12/h3H,2H2,1H3,(H,8,11,12)	GTMGELLVPUSBMG-UHFFFAOYSA-N	86061	A-304121	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86061	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86061&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			327764	136352161				1258		ZINC01567523	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184901	C[C@@H](NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1	InChI=1S/C25H31N3O5/c1-18(26-24(30)22-4-2-16-33-22)25(31)28-14-12-27(13-15-28)11-3-17-32-21-9-7-20(8-10-21)23(29)19-5-6-19/h2,4,7-10,16,18-19H,3,5-6,11-15,17H2,1H3,(H,26,30)/t18-/m1/s1	RTRADBQSZJIRMT-GOSISDBHSA-N	50158601	A-317920::CHEMBL361355::Furan-2-carboxylic acid ((R)-2-{4-[3-(4-cyclopropanecarbonyl-phenoxy)-propyl]-piperazin-1-yl}-1-methyl-2-oxo-ethyl)-amide	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158601&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10389213	104045280		CHEMBL361355		1216		ZINC28119372	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184902	O=C(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1	InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)	ACQBHJXEAYTHCY-UHFFFAOYSA-N	27213	4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole::CHEMBL14638::CHEMBL1795025::Ciproxifan	Alpha-2A adrenergic receptor		 42.66								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27213&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6422124	57298923		CHEMBL14638CHEMBL1795025		1265		ZINC01892860	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184903	NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1	InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)	UCAIEVHKDLMIFL-UHFFFAOYSA-N	22541	Clobenpropit::N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide::VUF 9153::VUF-9153::VUF9153	Alpha-2A adrenergic receptor		 17.38								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22541&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2790	49846355				1223		ZINC14951170	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184904	S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1	InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	QKDDJDBFONZGBW-UHFFFAOYSA-N	22914	CHEMBL260374::N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide::Thioperamide::US11622967, Compound Thioperamide	Alpha-2A adrenergic receptor		 125.89								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22914	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22914&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	FJZ	3MDM	3035905	49846728		CHEMBL260374		1267		ZINC13108134	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
187452	CCc1cc2c(ccc3cnn(CC(C)N)c23)o1	InChI=1S/C14H17N3O/c1-3-11-6-12-13(18-11)5-4-10-7-16-17(14(10)12)8-9(2)15/h4-7,9H,3,8,15H2,1-2H3	QLOOWOVVZLBYHU-UHFFFAOYSA-N	86441	CAS_3045225::NSC_3045225::YM348	Alpha-2A adrenergic receptor		 126								PDSP Ki	10.1016/j.ejphar.2003.10.004	10.7270/Q2ZG6QTV	14709324			Kimura, Y; Hatanaka, K; Naitou, Y; Maeno, K; Shimada, I; Koakutsu, A; Wanibuchi, F; Yamaguchi, T	Yamanouchi Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86441	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86441&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9921157	136352490						ZINC14952633	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182637	CNCC[C@H](Oc1cccc2ccccc12)c1cccs1	InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1	ZEUITGRIYCTCEM-KRWDZBQOSA-N	84745	CAS_136434-34-9::DULOXETINE::LY-248686::LY248686::USRE49340, Rank 5	Alpha-2A adrenergic receptor		 8600								PDSP Ki	10.1016/S0893-133X(01)00298-6	10.7270/Q25M648W	11750180			Bymaster, FP; Dreshfield-Ahmad, LJ; Threlkeld, PG; Shaw, JL; Thompson, L; Nelson, DL; Hemrick-Luecke, SK; Wong, DT	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84745&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	29E	4MMD,4MM6,6M38	60835	136350845	36808		DB00476			ZINC01536779	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182638	COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1	InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	PNVNVHUZROJLTJ-UHFFFAOYSA-N	82071	CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1016/S0893-133X(01)00298-6	10.7270/Q25M648W	11750180			Bymaster, FP; Dreshfield-Ahmad, LJ; Threlkeld, PG; Shaw, JL; Thompson, L; Nelson, DL; Hemrick-Luecke, SK; Wong, DT	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	VFX	8F4W	5656	131342645			DB00285		C07187	ZINC00896698	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182639	CNCC[C@H](Oc1cccc2ccccc12)c1cccs1	InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1	ZEUITGRIYCTCEM-KRWDZBQOSA-N	84745	CAS_136434-34-9::DULOXETINE::LY-248686::LY248686::USRE49340, Rank 5	Alpha-2A adrenergic receptor		 1000								PDSP Ki	10.1016/S0893-133X(01)00298-6	10.7270/Q25M648W	11750180			Bymaster, FP; Dreshfield-Ahmad, LJ; Threlkeld, PG; Shaw, JL; Thompson, L; Nelson, DL; Hemrick-Luecke, SK; Wong, DT	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84745&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	29E	4MMD,4MM6,6M38	60835	136350845	36808		DB00476			ZINC01536779	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182640	COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1	InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3	PNVNVHUZROJLTJ-UHFFFAOYSA-N	82071	CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655	Alpha-2A adrenergic receptor		 1000								PDSP Ki	10.1016/S0893-133X(01)00298-6	10.7270/Q25M648W	11750180			Bymaster, FP; Dreshfield-Ahmad, LJ; Threlkeld, PG; Shaw, JL; Thompson, L; Nelson, DL; Hemrick-Luecke, SK; Wong, DT	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	VFX	8F4W	5656	131342645			DB00285		C07187	ZINC00896698	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
182745	COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O	InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3	XMXHEBAFVSFQEX-UHFFFAOYSA-N	50034043	1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE	Alpha-2A adrenergic receptor		 162								PDSP Ki	10.1016/S0893-133X(01)00285-8	10.7270/Q21V5CHQ	11750183			Kalkman, HO; Subramanian, N; Hoyer, D	Novartis Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71360	103942259	65173	CHEMBL14376	DB04946	87		ZINC01548097	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186524	CNC(C)Cc1ccc2OCOc2c1	InChI=1S/C11H15NO2/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10/h3-4,6,8,12H,5,7H2,1-2H3	SHXWCVYOXRDMCX-UHFFFAOYSA-N	50010588	(RS)-3,4-(methylenedioxy)methamphetamine::1-(1,3-Benzodioxol-5-yl)-N-methyl-2-propanamine::1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine::3,4-methylenedioxymethamphetamine::CHEMBL43048::DL-(3,4-Methylenedioxy)methamphetamine::MDMA::N,alpha-dimethyl-1,3-benzodioxole-5-ethanamine::N-Methyl-3,4-methylenedioxyamphetamine	Alpha-2A adrenergic receptor		 2532								PDSP Ki	10.1124/mol.63.6.1223	10.7270/Q2FN14SJ	12761331			Setola, V; Hufeisen, SJ; Grande-Allen, KJ; Vesely, I; Glennon, RA; Blough, B; Rothman, RB; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010588&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	B41	3GM0	1615	103923364	1391	CHEMBL43048	DB01454	4574	C07577	ZINC00403053	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185389	Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl	InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	CEUORZQYGODEFX-UHFFFAOYSA-N	50130293	7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole	Alpha-2A adrenergic receptor		 74								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	9SC	7VR9,7E2Z,6A7P,7VOE,7WKZ	60795	104021727	31236	CHEMBL1112	DB01238	34	C12564	ZINC01851149	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185390	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2A adrenergic receptor		 184								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185391	CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	ZUXABONWMNSFBN-UHFFFAOYSA-N	22869	6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine	Alpha-2A adrenergic receptor		 142								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	49846683				38		ZINC19796155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185392	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2	PLDUPXSUYLZYBN-UHFFFAOYSA-N	78433	2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17	Alpha-2A adrenergic receptor		 314.1								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3372	252655189			DB00623		C07010	ZINC19203912	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185393	OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1	InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	LNEPOXFFQSENCJ-UHFFFAOYSA-N	21398	4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1	Alpha-2A adrenergic receptor		 1130								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	GMJ	6X10,6DJZ,6LUQ	3559	49689470	5613	CHEMBL54CHEMBL545608	DB00502	86	C01814	ZINC00537822	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185394	CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12	InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3	XJGVXQDUIWGIRW-UHFFFAOYSA-N	22871	13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine	Alpha-2A adrenergic receptor		 150.8								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3964	49846685	50841	CHEMBL831	DB00408	205	C07104	ZINC19796158	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185395	CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12	InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3	KLPWJLBORRMFGK-UHFFFAOYSA-N	50130290	3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban	Alpha-2A adrenergic receptor		 1097								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23897	104021724		CHEMBL460	DB01618	207	C07230	ZINC22002218	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185396	CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3	WXPNDRBBWZMPQG-UHFFFAOYSA-N	82479	CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2	Alpha-2A adrenergic receptor		 314.1								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4585	136350450				47		ZINC03873830	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185397	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1	InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2	RGCVKNLCSQQDEP-UHFFFAOYSA-N	50130273	2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine	Alpha-2A adrenergic receptor		 810.5								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4748	104021707	8028	CHEMBL567	DB00850	209	C07427	ZINC19228902	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185398	Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1	InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)	YVUQSNJEYSNKRX-UHFFFAOYSA-N	50334150	1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238	Alpha-2A adrenergic receptor		 1593								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	1II	7WLL	16362	125084252	8212	CHEMBL1423	DB01100	90	C07566	ZINC19796084	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185399	OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12	InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2	URKOMYMAXPYINW-UHFFFAOYSA-N	50095890	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE	Alpha-2A adrenergic receptor		 3630								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5002	103993497	8707	CHEMBL716	DB01224	50	C07397	ZINC19632628	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185400	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone	Alpha-2A adrenergic receptor		 150.8								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252	8871	CHEMBL85	DB00734	96		ZINC00538312	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185401	Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12	InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	GZKLJWGUPQBVJQ-UHFFFAOYSA-N	50001786	1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole	Alpha-2A adrenergic receptor		 640								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60149	103916159	9122	CHEMBL12713	DB06144	98	C07567	ZINC00538337	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185402	CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1	InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3	KLBQZWRITKRQQV-UHFFFAOYSA-N	50002338	(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine	Alpha-2A adrenergic receptor		 134.3								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LZU	4I1R,4UHX	5452	103916644	9566	CHEMBL479	DB00679	100		ZINC01530697	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185403	CN(C)S(=O)(=O)c1ccc2Sc3ccccc3C(=CCCN3CCN(C)CC3)c2c1	InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3	GFBKORZTTCHDGY-UHFFFAOYSA-N	86187	CAS_22189-31-7::NSC_5454::THIOTHIXENE	Alpha-2A adrenergic receptor		 79.9								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86187&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			941650	136352287						ZINC29747244	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185404	CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3	ZEWQUBUPAILYHI-UHFFFAOYSA-N	79181	10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566	Alpha-2A adrenergic receptor		 653.7								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TFP	4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0	5566	252655893			DB00831		C07168	ZINC19418959	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185405	Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12	InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	MVWVFYHBGMAFLY-UHFFFAOYSA-N	50048803	5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE	Alpha-2A adrenergic receptor		 160								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60854	103979184	10119	CHEMBL708	DB00246	59	C07568	ZINC00538550	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186623	Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl	InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	CEUORZQYGODEFX-UHFFFAOYSA-N	50130293	7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole	Alpha-2A adrenergic receptor		 74.3								PDSP Ki	10.1038/sj.npp.1300203	10.7270/Q2639N9T	12784105			Shapiro, DA; Renock, S; Arrington, E; Chiodo, LA; Liu, LX; Sibley, DR; Roth, BL; Mailman, R	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	9SC	7VR9,7E2Z,6A7P,7VOE,7WKZ	60795	104021727	31236	CHEMBL1112	DB01238	34	C12564	ZINC01851149	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186846	CC(N)C(=O)c1ccccc1	InChI=1S/C9H11NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7H,10H2,1H3	PUAQLLVFLMYYJJ-UHFFFAOYSA-N	86286	CAS_62258::Cathinone, (-)::NSC_62258	Alpha-2A adrenergic receptor		 6808								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86286&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			107786	136352386	59332					ZINC53165482	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186847	CNC(C)C(=O)c1ccccc1	InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	LPLLVINFLBSFRP-UHFFFAOYSA-N	86285	CAS_1576::Methcathinone, (-)::NSC_1576	Alpha-2A adrenergic receptor		 9017								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86285&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1576	136352385						ZINC00403055	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186848	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2A adrenergic receptor		 3024								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186849	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2A adrenergic receptor		 1330								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186850	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 1.36								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186851	CNC(C)C(O)c1ccccc1	InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3	KWGRBVOPPLSCSI-UHFFFAOYSA-N	86284	CAS_24221-86-1::CAS_5032::Ephedrine,(+)::Ephedrine,(-)::NSC_5032::Pseudoephedrine, (-)	Alpha-2A adrenergic receptor		 2011								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86284&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5032	136352384						ZINC00074840	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186852	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2A adrenergic receptor		 2608								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
186853	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2A adrenergic receptor		 2598								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185685	NC(CSSCC(N)C(O)=O)C(O)=O	InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)	LEVWYRKDKASIDU-UHFFFAOYSA-N	86199	CAS_595::CAS_67678::D-cystine::L-cystine::NSC_595::NSC_67678	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86199&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	IYY	8DKM,7ZKW	595	136352299	17376				C01420	ZINC01532673	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185686	N[C@H](CCS(O)(=O)=O)C(O)=O	InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m1/s1	VBOQYPQEPHKASR-GSVOUGTGSA-N	86196	D-homocysteic acid	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86196&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185861	136352296					C15521	ZINC02545126	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185687	N[C@H](CCS(O)=O)C(O)=O	InChI=1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m1/s1	PDNJLMZEGXHSCU-GSVOUGTGSA-N	86197	D-homocysteine sulfinic acid	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86197&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23844143	136352297					C01615	ZINC25720437	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185688	N[C@@H]1CCSC1=O	InChI=1S/C4H7NOS/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m1/s1	KIWQWJKWBHZMDT-GSVOUGTGSA-N	86205	D-homocysteine thiolactone	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86205&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			7057932	136352305						ZINC54009854	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185689	CSCCC(N)C(O)=O	InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)	FFEARJCKVFRZRR-UHFFFAOYSA-N	86195	CAS_6137::CAS_84815::D-methionine::L-methionine::NSC_6137::NSC_84815	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86195&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	MED	4GLS,4GLU,1Y9Q,1ZUE,5CGO,5CGN,1TKJ,6CNU,3TRY,7P5R,6DZX,3GP4,3TRV,8F16,6WI3,6JV7,4OIJ,4OIK,6PHQ,6PHN,6PHM,1KQ0,5I5A,5I5B,6WKB,2Q33,7UO8,5HHD,5XPK,3TJW,5I1P,5I1S,5I1O,5I1N	876	136352295	16811				C01733	ZINC01532766	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185690	NC(CCS(O)(=O)=O)C(O)=O	InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)	VBOQYPQEPHKASR-UHFFFAOYSA-N	50164447	2-amino-4-sulfobutanoic acid::CHEMBL191727::DL-homocysteic acid	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164447&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HJT	6Q6J	92117	104050228		CHEMBL191727			C15521	ZINC02567965	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185691	NC(CCS)C(O)=O	InChI=1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)	FFFHZYDWPBMWHY-UHFFFAOYSA-N	86202	CAS_778::DL-homocysteine::NSC_778	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86202&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HCS	4YGW,3BOF,4HPD,2N0I,3BQ5,1Q8J,2LP2,4M3P,4L6H,2CI5,1U22,3BOL,3VK4,5OTT,5OTU,5OTV,5OTW,4L5Z,1JVI,6IQG,6R28,5F2Y,5WT5,4XFI,4XFA,4XF9,4XF4,1JQW,1XDJ,8BIX,4QQU,5X30,4PIZ,4PIY,5DMM,1Q8A,6VJU,6PO4,7F1V	778	136352302	17230				C05330	ZINC00895703	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185692	NC(CS(O)(=O)=O)C(O)=O	InChI=1S/C3H7NO5S/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)	XVOYSCVBGLVSOL-UHFFFAOYSA-N	85473	L-Cysteic acid, 8::L-cysteic acid	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85473&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	00C	3FII	25701	136351573	21260				C15521	ZINC04228276	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185693	NC(CS)C(O)=O	InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)	XUJNEKJLAYXESH-UHFFFAOYSA-N	86203	CAS_5862::L-cysteine::NSC_5862	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86203&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	BTC	1B23,1D7P,1ECX,1GKM,1GL3,1HFE,1I1A,1LI7,1MB4,1N26,1N31,1O7S,1PQU,1R4S,1R51,1RZG,1SSQ,1T3D,1V1Q,1XT8,208L,2D32,2D33,2DF3,2FUB,2G5R,2IBN,2IC1,2ICQ,2IO8,2IX7,2PAD,2V43,2WB9,2YJP,2YLN,2ZSV,3A9Y,3BM5,3C01,3ENJ,3GVD,3P47,3PZR,3Q0E,3TZ6,3V6O,4BB2,4BFE,4BFG,4BFI,4FF9,4G1P,4H7O,4HPC,4IEV,4IEW,4JH8,4JTO,4KSZ,4LMB,4NB0,4NB1,4OTZ,4OWD,4QM8,4QM9,4XF0,4XF1,4XF3,4XFG,4XFH,4YTG,4Z82,4ZU9,5B36,5DB5,5EH1,5EIG,5HCC,5HCD,5HCE,7API,8API,9API	594	136352303	15356				C00736	ZINC00895347	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185694	NC(CS(O)=O)C(O)=O	InChI=1S/C3H7NO4S/c4-2(3(5)6)1-9(7)8/h2H,1,4H2,(H,5,6)(H,7,8)	ADVPTQAUNPRNPO-UHFFFAOYSA-N	86194	CAS_109::L-cysteine sulfinic acid::NSC_109	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86194&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CSD	1EU1,6IKY,6IKT,6Z9O,5NY7,3E9Y,3H4H,6W0U,1TO9,3PHU,3VYH,3VYG,6MTG,4U8E,4Y1R,4Y1F,4G6W,5Z3D,5F8E,5F8F,5F8C,3PSZ,4QYT,1REV,1JKH,3TKK,3TKS,6Z9G,1BQ6,4AGI,6WE7,4NYO,4NYP,3WVD,3WVE,6R6U,4Z37,3FIV,3A8M,7L1P,1XW4,6PT4,3HHT,6Z8M,1FNK,6RUC,1VRU,1Z8N,7LR3,1BI5,4OMR,3H56,3QZ5,3QZ9,2QUG,6FTQ,7Z0V,2Z1D,6DXB,6DXC,6DXA,6DXD,6DX9,7PI0,6MU0,3U7M,3U7L,3U7N,3U7K,5WC4,5B6N,6B4R,1VI9,2ZPB,2ZPG,5K6R,5K6Q,5K6T,5IPG,5FZO,3QOR,7W6G,1SUC,1SUB,1SUD,1Q9U,4AY8,4AY7,7QOY,7QOU,7QOP,7QOM,2FHX,6RTP,3PG8,3QYG,3QYH,4PSS,4PST,4PSY,1TKT,2OPQ,2OPP,2OPS,2OPR,2OPL,2ZZD,7PJN,3I1H,3KI8,1WUO,4OQ4,8ET5,8ET4,2PVZ,1OBF,5V2W,5UR0,4CHL,2C47,5JSH,5JSU,3SMH,2J16,5IMF,5GK0,6RIZ,2R3Q,2R3P,2R3I,2R3K,2R3J,2R3M,2R3L,2R3O,2R3N,5INY,1LW2,1LW0,1LWC,1LWF,1LWE,4IEF,6ISQ,6G4R,5NAI,6N1A,2X1E,3HJ0,4NT8,3WEU,4R0V,4RYB,3QXE,1U9C,4ZGJ,4ZGE,4ZGD,1EKQ,1EKK,1MHW,3X26,3X25,3X24,3X20,3X28,7F87,7F8S,2HL8,3AWJ,3DLE,3DLG,1Q79,1Q78,3C5Y,3A8H,3OQP,3OQI,1DNC,1TKZ,5FQA,2BGA,2BG6,5JT1,1UGR,3SLE,4YUF,2ZCF,5VEX,5VEW,6G5M,5HWR,7AYJ,2IMZ,7U1D,7U1U,4P2G,4EKF,6ZK6,3T8E,4YKG,5NUE,5JQN,3ZJG,3ZJF,2V9S,1OBB,8ADD,6W42,1OKI,7XCF,7W8L,7W8M,4KPH,4U2C,3R66,1JLQ,1JLC,1JLB,1JLE,1JLG,4G2O,7BUR,7BUS,2ETF,7FFA,3P5U,1TL3,1TL1,5IMD,5IMZ,2BFZ,2GCU,6H2U,3L87,6TYY,3BC2,3BC3,3GEF,5SYA,5VF5,2ACT,1DIN,6BKA,1YBH,4LDK,2VYN,2VYV,1YM9,2DD5,1YSL,4OB1,4OB0,4OB3,4OB2,7CTM,1TVZ,1EP4,1UKK,7ZM9,5CPD,1RTH,1RTJ,1RT1,1RT3,1RT2,1RT5,1RT4,1RT7,1RT6,3T6S,1EE0,7STQ,3DMJ,6FXS,1JLA,1JLF,7TZZ,2HNY,2HNZ,2HND,1IRE,3SED,4GE3,5Z89,3EU7,3EUO,3EUT,3EUQ,3MI2,7ARF,3AWK,2E2M,4XLL,1YI1,1YI0,6YG4,4QIB,1TXT,3A9C,2QDY,2D5H,2D51,2D52,2RK6,4WPZ,1V5I,3NRA,7PNK,1VJE,2DPP,7JH0,3UK7,3CWM,3CWL,6UTN,2VB7,5IZD,3DOL,3DOK,2WLX,2WLR,2WL4,4AH4,1I86,3DM2,5IO0,1S1W,1S1V,1S1U,1S1T,1S1X,6VX2,6GW3,3SQZ,5SY9,5WSE,5WSD,5WSF,5H5S,7B1Y,7B1V,4GE0,4WZ0,2OJP,4M5P,5LRY,5LRX,1YHY,4QJE,3A8G,3A8L,3A8O,2D0Q,4WQ8,4WQ9,5G5H,2P0U,7B23,1R7A,1D6I,1D6H,3EA4,5UC5,7QOV,5K2O,5K3S,3H8C,5J78,2X1D,5W3V,1OEU,3SGU,2H9W,6L2D,6L2E,6L2F,5IOW,2C9H,1I88,1I89,5W8Q,6Z7R,3TB2,3LQY,2GDU,7NAY,1SOA,6IL2,6IL0,2RIL,2D3M,3IW3,7A74,7LVC,7UNZ,1W8C,4UAM,3UIO,3UIP,5C7I,4BPY,3CYF,5V5H,1Q1Y,5G5G,1DTT,1DTQ,1VGX,2CYZ,7FBQ,3IL9,4U85,2OAN,1YHZ,1I8B,2AHJ,6Z8J,1ACD,1TKX,1QMV,7T8L,5Y0S,5Y0T,1JWX,4GD7,7KJ0,1FK9,1FKP,1FKO,2G82,6I7R,6I7Q,4FLM,1QFM,2DXB,2DXC,4PIO,1UGP,1OCH,4P5P,4TTG,4RGC,2EG3,2HAI,4PTH,4PTJ,3F5V,2CZ0,2CZ7,2CZ6,4NJ3,1KLM,3EZG,1C1C,1C1B,4V2P,3OP0,4N12,6K5J,2ZPH,2ZPI,2ZPE,2ZPF,6XKH,1QLV,2NQT,1GZ8,6YCB,2D5F,1RTI,2CZ1,7C9J,4I07,4IW7,6ZA1,6C9U,5E68,4ORN,4D52,4Y0N,6B6L,2BC0,2BC2,7MKV,1C0T,1C0U,6ED0,6JFO,1VRT,6QUN,4FM4,6ESZ	109	136352294				4695	C01615	ZINC12501661	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185695	NC(CSSCC(N)C(O)=O)C(O)=O	InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)	LEVWYRKDKASIDU-UHFFFAOYSA-N	86199	CAS_595::CAS_67678::D-cystine::L-cystine::NSC_595::NSC_67678	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86199&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	IYY	8DKM,7ZKW	595	136352299	17376				C01420	ZINC01532673	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185696	N[C@@H](CCS(O)(=O)=O)C(O)=O	InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1	VBOQYPQEPHKASR-VKHMYHEASA-N	50220147	(S)-2-amino-4-sulfobutanoic acid::CHEMBL230951::L-2-amino-4-sulfobutyric acid::L-Homocysteate::L-homocysteic acid	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220147&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HJT	6Q6J	177491	104093189		CHEMBL230951			C16511	ZINC02567965	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185697	N[C@@H](CCS(O)=O)C(O)=O	InChI=1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1	PDNJLMZEGXHSCU-VKHMYHEASA-N	86201	L-homocysteine sulfinic acid	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86201&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			75896	136352301					C01615	ZINC12953438	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185698	N[C@H]1CCSC1=O	InChI=1S/C4H7NOS/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m0/s1	KIWQWJKWBHZMDT-VKHMYHEASA-N	86198	CAS_134505::L-homocysteine thiolactone::NSC_134505	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86198&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			134505	136352298	60315					ZINC54009855	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
185699	CSCCC(N)C(O)=O	InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)	FFEARJCKVFRZRR-UHFFFAOYSA-N	86195	CAS_6137::CAS_84815::D-methionine::L-methionine::NSC_6137::NSC_84815	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86195&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	MED	4GLS,4GLU,1Y9Q,1ZUE,5CGO,5CGN,1TKJ,6CNU,3TRY,7P5R,6DZX,3GP4,3TRV,8F16,6WI3,6JV7,4OIJ,4OIK,6PHQ,6PHN,6PHM,1KQ0,5I5A,5I5B,6WKB,2Q33,7UO8,5HHD,5XPK,3TJW,5I1P,5I1S,5I1O,5I1N	876	136352295	16811				C01733	ZINC01532766	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184519	CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31	InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	VMWNQDUVQKEIOC-CYBMUJFWSA-N	50001955	(-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53	Alpha-2A adrenergic receptor		 141.25								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	OR9	7JVQ	6005	103916308	48538	CHEMBL53	DB00714	33		ZINC00009073	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184520	CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C	InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1	OZVBMTJYIDMWIL-AYFBDAFISA-N	81993	BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-)	Alpha-2A adrenergic receptor		 10.96								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	08Y	6VMS,3UA1,7JVR,5VCG	31101	131342567			DB01200		C06856	ZINC53683151	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184521	CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(Cc3c[nH]c4cccc2c34)N(CC=C)C1	InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)	KORNTPPJEAJQIU-UHFFFAOYSA-N	86052	CAS_54746::Cabergoline::NSC_54746	Alpha-2A adrenergic receptor		 12.02								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86052&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2512	136352152							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184522	CCN(CC)C(=O)N[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34	InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18-/m1/s1	BKRGVLQUQGGVSM-RDTXWAMCSA-N	22867	1,1-diethyl-3-[(8beta)-6-methyl-9,10-didehydroergolin-8-yl]urea::3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),2,9,12(16),13-pentaen-4-yl]urea::8R-lisuride::LISURIDE	Alpha-2A adrenergic receptor		 0.05								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22867&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11957615	49846681						ZINC03831002	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184523	CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13	InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1	YEHCICAEULNIGD-MZMPZRCHSA-N	50028421	9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid::CHEMBL1275::LY-127809::PERGOLIDE MESYLATE::Pergolide::Permax	Alpha-2A adrenergic receptor		 50.12								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028421&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			47811	103937709	8021	CHEMBL1275	DB01186		C07425	ZINC03786466	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184524	C(N1CCN(CC1)c1ncccn1)c1ccc2OCOc2c1	InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2	OQDPVLVUJFGPGQ-UHFFFAOYSA-N	85092	CAS_3605-01-4::NSC_4850::Piribedil	Alpha-2A adrenergic receptor		 89.13								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85092	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85092&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4850	136351192						ZINC19537374	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184525	CCCNC1CCc2nc(N)sc2C1	InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)	FASDKYOPVNHBLU-UHFFFAOYSA-N	50017550	CHEMBL76399::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX)::Pramipexole	Alpha-2A adrenergic receptor		 1698.24								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017550&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	G6L	7CMU	4885	103928818		CHEMBL76399				ZINC03831352	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184526	CCCN1CCC[C@@H]2Cc3nc(N)ncc3C[C@@H]12	InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m1/s1	TUFADSGTJUOBEH-ZWNOBZJWSA-N	50016017	(5aR,9aR)-6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine::(5aR,9aR)-6-propyl-5,5a,6,7,8,9,9a,10-octahydropyrido[2,3-g]quinazolin-2-amine::6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine(Quinelorane)::CHEMBL155731::Quinelorane::Quinerolane	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016017&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57242	103927698		CHEMBL155731		954		ZINC00005041	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184527	CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12	InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	FTSUPYGMFAPCFZ-ZWNOBZJWSA-N	84637	CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54562	136350737		CHEMBL240773				ZINC25724686	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184528	CCCN(CCC)CCc1cccc2NC(=O)Cc12	InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)	UHSKFQJFRQCDBE-UHFFFAOYSA-N	50020680	4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE	Alpha-2A adrenergic receptor		 1862.09								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5095	103931441	8888	CHEMBL589	DB00268	7295	C07564	ZINC00002041	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184529	Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1	InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2	HGEYJZMMUGWEOT-UHFFFAOYSA-N	50002173	3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole	Alpha-2A adrenergic receptor		 6.17								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			219050	103916479	48558	CHEMBL431367		52		ZINC01548439	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184530	Nc1nc2CCN(CC=C)CCc2s1	InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12)	DHSSDEDRBUKTQY-UHFFFAOYSA-N	86053	B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374	Alpha-2A adrenergic receptor		 37.15								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86053&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5374	136352153		CHEMBL279085				ZINC00006644	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184531	CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1	InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1	JOAHPSVPXZTVEP-YXJHDRRASA-N	50017519	1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-urea::CHEMBL73151::Terguride	Alpha-2A adrenergic receptor		 0.30								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017519&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			443951	103928787		CHEMBL73151				ZINC03811327	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
184532	C[NH+](C)C1CCc2cc(O)c(O)cc2C1	InChI=1S/C12H17NO2/c1-13(2)10-4-3-8-6-11(14)12(15)7-9(8)5-10/h6-7,10,14-15H,3-5H2,1-2H3/p+1	JWLJBTDXCBIGBW-UHFFFAOYSA-O	50025206	(6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-ammonium::TL99	Alpha-2A adrenergic receptor		 41.69								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025206&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44299913	103935110						ZINC05965207	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
187653	CCCN(CCC)CCc1cccc2NC(=O)Cc12	InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)	UHSKFQJFRQCDBE-UHFFFAOYSA-N	50020680	4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE	Alpha-2A adrenergic receptor		 1862.09								PDSP Ki	10.1124/jpet.103.062398	10.7270/Q29S1PM2	14978194			Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5095	103931441	8888	CHEMBL589	DB00268	7295	C07564	ZINC00002041	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
187654	CCCN1CCOC2C1CCc1ccc(cc21)C(N)=O	InChI=1S/C16H22N2O2/c1-2-7-18-8-9-20-15-13-10-12(16(17)19)4-3-11(13)5-6-14(15)18/h3-4,10,14-15H,2,5-9H2,1H3,(H2,17,19)	XKTRZPQOQOCNJU-UHFFFAOYSA-N	86475	S32504	Alpha-2A adrenergic receptor		 8128.31								PDSP Ki	10.1124/jpet.103.062398	10.7270/Q29S1PM2	14978194			Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86475&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9925530	136352524						ZINC34031100	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
189039	COc1cccc(C(O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC	InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3	HXTGXYRHXAGCFP-UHFFFAOYSA-N	50232153	(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol::(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::CHEMBL257283::MDL 100907::MDL-100907	Alpha-2A adrenergic receptor		 1900								PDSP Ki	10.1038/sj.npp.1300819	10.7270/Q2KW5DMS	15999145			Pehek, EA; Nocjar, C; Roth, BL; Byrd, TA; Mabrouk, OS	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50232153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50232153&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60858	104055427		CHEMBL257283				ZINC01851117	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
189040	OC(C1CCN(CCc2ccccc2)CC1)c1ccccc1	InChI=1S/C20H25NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19-20,22H,11-16H2	AXNGJCOYCMDPQG-UHFFFAOYSA-N	50004327	(1-Phenethyl-piperidin-4-yl)-phenyl-methanol::CHEMBL18972::Glemanserin::MDL 11,939::MDL-11939	Alpha-2A adrenergic receptor		 1586								PDSP Ki	10.1038/sj.npp.1300819	10.7270/Q2KW5DMS	15999145			Pehek, EA; Nocjar, C; Roth, BL; Byrd, TA; Mabrouk, OS	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004327&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71781	103918010		CHEMBL18972				ZINC01843091	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
189041	CN(C)CCON=C(C=Cc1ccc(O)cc1)c1ccccc1F	InChI=1S/C19H21FN2O2/c1-22(2)13-14-24-21-19(17-5-3-4-6-18(17)20)12-9-15-7-10-16(23)11-8-15/h3-12,23H,13-14H2,1-2H3	VAIOZOCLKVMIMN-UHFFFAOYSA-N	81780	CAS_6438382::NSC_6438382::SR 46349B	Alpha-2A adrenergic receptor		 725.9								PDSP Ki	10.1038/sj.npp.1300819	10.7270/Q2KW5DMS	15999145			Pehek, EA; Nocjar, C; Roth, BL; Byrd, TA; Mabrouk, OS	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81780&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5486684	131342354						ZINC14953472	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
190326	CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC	InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)	NTJOBXMMWNYJFB-UHFFFAOYSA-N	81790	Amisulpride::CAS_71675-85-9::NSC_2159::US10167256, Amisulpride::US10259786, Amisulpride	Alpha-2A adrenergic receptor		 1114								PDSP Ki	10.1007/s00213-009-1521-8	10.7270/Q2TB15G7	19337725			Abbas, AI; Hedlund, PB; Huang, XP; Tran, TB; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81790&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2159	131342364	64045		DB06288	963		ZINC01846088	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
187979	CCc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1	InChI=1S/C23H23BrCl2N4O/c1-2-18-21(23(31)28-29-12-4-3-5-13-29)27-30(20-11-10-17(25)14-19(20)26)22(18)15-6-8-16(24)9-7-15/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)	HMXDWDSNPRNUKI-UHFFFAOYSA-N	50171290	5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide::CHEMBL189676::SR 147778	Alpha-2A adrenergic receptor		 1000								PDSP Ki	10.1124/jpet.104.067884	10.7270/Q2RR1WTX	15131245			Rinaldi-Carmona, M; Barth, F; Congy, C; Martinez, S; Oustric, D; P&eacute;rio, A; Poncelet, M; Maruani, J; Arnone, M; Finance, O; Soubri&eacute;, P; Le Fur, G	Sanofi-Synthelabo Recherche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171290&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9849616	104057543		CHEMBL189676				ZINC01549068	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
189337	NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1	InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)	ROFVXGGUISEHAM-UHFFFAOYSA-N	26739	3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate::CHEMBL184238::URB 597::URB-597::URB597::US9187413, 1a (URB597)	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1073/pnas.0509591102	10.7270/Q2F47MQJ	16352709			Gobbi, G; Bambico, FR; Mangieri, R; Bortolato, M; Campolongo, P; Solinas, M; Cassano, T; Morgese, MG; Debonnel, G; Duranti, A; Tontini, A; Tarzia, G; Mor, M; Trezza, V; Goldberg, SR; Cuomo, V; Piomelli, D	McGill University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26739&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1383884	57298451		CHEMBL184238		4339		ZINC01238258	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
189567	COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1	InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	SBPRIAGPYFYCRT-UHFFFAOYSA-N	86708	CAS_146714-97-8::CHEMBL31354::CHEMBL514874::CHEMBL537403::NSC_104911::WAY 100,635	Alpha-2A adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-006-0490-4	10.7270/Q2HX1B8P	16915381			Chemel, BR; Roth, BL; Armbruster, B; Watts, VJ; Nichols, DE	Purdue University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86708&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5684	136352757		CHEMBL537403CHEMBL514874CHEMBL31354				ZINC52541473	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50021040	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2A adrenergic receptor		 16.0								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50021065	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2A adrenergic receptor		 2.60								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50021070	COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	XHLHZPFSBCZVEA-HOFKKMOUSA-N	50131351	(3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860	Alpha-2A adrenergic receptor		 93								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324737	104022535		CHEMBL92860				ZINC22445308	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239028	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2A adrenergic receptor		 30.0								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
445397	Cc1ccc2N=C(N3CCN(CC(C)(C)C(O)=O)CC3)c3cc(Cl)sc3Oc2c1	InChI=1S/C21H24ClN3O3S/c1-13-4-5-15-16(10-13)28-19-14(11-17(22)29-19)18(23-15)25-8-6-24(7-9-25)12-21(2,3)20(26)27/h4-5,10-11H,6-9,12H2,1-3H3,(H,26,27)	PSYAJOBNPBYKRW-UHFFFAOYSA-N	255474	US9481688, 1::US9481688, 3	Alpha-2A adrenergic receptor		>8990								US Patent		10.7270/Q25D8QRW		aid1803573	US9481688	Ledgard, AJ	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=255474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=255474&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71212556	347830110							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50021045	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2A adrenergic receptor		 30								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50019955	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2A adrenergic receptor		 48								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50021049	COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	XHLHZPFSBCZVEA-HOFKKMOUSA-N	50131351	(3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860	Alpha-2A adrenergic receptor		 93.0								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324737	104022535		CHEMBL92860				ZINC22445308	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50021056	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2A adrenergic receptor		 16								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50021072	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2A adrenergic receptor		 2.6								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50028496	CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1	InChI=1S/C17H17FN2O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	OOYTZYZXCMCMSZ-UHFFFAOYSA-N	50002903	CHEMBL223836	Alpha-2A adrenergic receptor					 105					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002903&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11211035	242056299		CHEMBL223836					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50028657	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2A adrenergic receptor		 138								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50028672	C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m0/s1	OGOLMGZJNRNULQ-ZDUSSCGKSA-N	50417354	CHEMBL396013	Alpha-2A adrenergic receptor					 74					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417354&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10333157	163366378		CHEMBL396013				ZINC00009140	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50028679	C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m1/s1	OGOLMGZJNRNULQ-CYBMUJFWSA-N	50417353	CHEMBL242265	Alpha-2A adrenergic receptor					 28840					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417353&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11043720	163366377		CHEMBL242265				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50039005	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2A adrenergic receptor		 1100								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50040311	COC(=O)C1=C(C)NC(C)=C([C@H]1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,37H,11,18-23H2,1-3H3/t33-/m0/s1	SVJMLYUFVDMUHP-XIFFEERXSA-N	50453799	Niguldipine	Alpha-2A adrenergic receptor		 645								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453799&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60602	225146125					C11236		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50036161	CC(c1cnc[nH]1)c1cccc2ccccc12	InChI=1S/C15H14N2/c1-11(15-9-16-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13/h2-11H,1H3,(H,16,17)	DZSQSLQSMKNVBV-UHFFFAOYSA-N	50036910	4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole::CHEMBL306751	Alpha-2A adrenergic receptor			 12300							ChEMBL	10.1021/jm00041a011	10.7270/Q26110ZR	7914537			Hong, SS; Romstedt, KJ; Feller, DR; Hsu, FL; Cupps, TL; Lyon, RA; Miller, DD	Ohio State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036910&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132111	103944551		CHEMBL306751				ZINC13450482	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047506	Fc1cccc2CCC3(CNC=N3)Cc12	InChI=1S/C12H13FN2/c13-11-3-1-2-9-4-5-12(6-10(9)11)7-14-8-15-12/h1-3,8H,4-7H2,(H,14,15)	HLTXXGYZKSNOBQ-UHFFFAOYSA-N	50031301	8'-fluorospiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]::CHEMBL131220	Alpha-2A adrenergic receptor		 12								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031301&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10081626	103940002		CHEMBL131220				ZINC13743709	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047511	NC1=NC2(CO1)CCc1cccc(Cl)c1C2	InChI=1S/C12H13ClN2O/c13-10-3-1-2-8-4-5-12(6-9(8)10)7-16-11(14)15-12/h1-3H,4-7H2,(H2,14,15)	OAXNLMLMEYQSSS-UHFFFAOYSA-N	50031306	8-chlorospiro[1,2,3,4-tetrahydronaphthalene-2,4'-(4',5'-dihydro[1,3]oxazole)]-2'-amine::CHEMBL133231	Alpha-2A adrenergic receptor		 1.6								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031306&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9837600	103940005		CHEMBL133231				ZINC00006736	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047512	COc1ccc2CCC3(CNC=N3)Cc2c1	InChI=1S/C13H16N2O/c1-16-12-3-2-10-4-5-13(7-11(10)6-12)8-14-9-15-13/h2-3,6,9H,4-5,7-8H2,1H3,(H,14,15)	PCMFDIVLXLOWGP-UHFFFAOYSA-N	50031308	7'-methoxyspiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]::CHEMBL133579	Alpha-2A adrenergic receptor		 51								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031308&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10036256	103940006		CHEMBL133579				ZINC13743731	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047515	Clc1cc(Cl)c2CCC3(CNC=N3)Cc2c1	InChI=1S/C12H12Cl2N2/c13-9-3-8-5-12(6-15-7-16-12)2-1-10(8)11(14)4-9/h3-4,7H,1-2,5-6H2,(H,15,16)	JVXCQBZATLABHQ-UHFFFAOYSA-N	50031324	5',7'-dichlorospiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]::CHEMBL338683	Alpha-2A adrenergic receptor		 3								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031324&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11777109	103940010		CHEMBL338683				ZINC13743723	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047517	COc1cccc2CC3(CNC=N3)CCc12	InChI=1S/C13H16N2O/c1-16-12-4-2-3-10-7-13(6-5-11(10)12)8-14-9-15-13/h2-4,9H,5-8H2,1H3,(H,14,15)	YTCVRHOTCDVIGI-UHFFFAOYSA-N	50031316	5'-methoxyspiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]::CHEMBL336332	Alpha-2A adrenergic receptor		 12								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031316&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10262765	103940008		CHEMBL336332				ZINC13743737	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047518	FC(F)(F)c1ccc(Cl)c(c1)N=C1NCCN1	InChI=1S/C10H9ClF3N3/c11-7-2-1-6(10(12,13)14)5-8(7)17-9-15-3-4-16-9/h1-2,5H,3-4H2,(H2,15,16,17)	WIAICRSVMJHHJL-UHFFFAOYSA-N	50027067	(2-Chloro-5-trifluoromethyl-phenyl)-(4,5-dihydro-1H-imidazol-2-yl)-amine::(2-Chloro-5-trifluoromethyl-phenyl)-imidazolidin-2-ylidene-amine (St-587)::CHEMBL101340	Alpha-2A adrenergic receptor		 1560								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027067	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027067&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			114697	103936649		CHEMBL101340		513		ZINC53165707	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047521	COc1ccc2CC3(CNC=N3)CCc2c1	InChI=1S/C13H16N2O/c1-16-12-3-2-11-7-13(8-14-9-15-13)5-4-10(11)6-12/h2-3,6,9H,4-5,7-8H2,1H3,(H,14,15)	YSSOIVRDCKNHKM-UHFFFAOYSA-N	50031326	6'-methoxyspiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]::CHEMBL336970	Alpha-2A adrenergic receptor		 87.0								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031326&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10398419	103940011		CHEMBL336970				ZINC13743733	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047523	Cc1ccc2CCC3(CNC=N3)Cc2c1	InChI=1S/C13H16N2/c1-10-2-3-11-4-5-13(7-12(11)6-10)8-14-9-15-13/h2-3,6,9H,4-5,7-8H2,1H3,(H,14,15)	NRGOCGDSGZTYDK-UHFFFAOYSA-N	50031311	7'-methylspiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]::CHEMBL98471	Alpha-2A adrenergic receptor		 7.0								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031311&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10198108	103940007		CHEMBL98471				ZINC26739301	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047531	COc1cccc2CCC3(CNC=N3)Cc12	InChI=1S/C13H16N2O/c1-16-12-4-2-3-10-5-6-13(7-11(10)12)8-14-9-15-13/h2-4,9H,5-8H2,1H3,(H,14,15)	ZZZDJNQQTGBTNX-UHFFFAOYSA-N	50031330	8'-methoxyspiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]::CHEMBL131417	Alpha-2A adrenergic receptor		 51								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031330&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10036255	103940013		CHEMBL131417				ZINC13743727	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50047537	C1NC=NC11CCc2ccccc2C1	InChI=1S/C12H14N2/c1-2-4-11-7-12(8-13-9-14-12)6-5-10(11)3-1/h1-4,9H,5-8H2,(H,13,14)	SLCMAHBWLUETAH-UHFFFAOYSA-N	50031319	CHEMBL130853::spiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]	Alpha-2A adrenergic receptor		 34								ChEMBL	10.1021/jm00020a021	10.7270/Q2DV1HXN	7562941			Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031319&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10176433	103940009		CHEMBL130853				ZINC27322561	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50046579	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2A adrenergic receptor		 2.7								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50046586	Cc1c(Nc2ncc[nH]2)ccc2OCCOc12	InChI=1S/C12H13N3O2/c1-8-9(15-12-13-4-5-14-12)2-3-10-11(8)17-7-6-16-10/h2-5H,6-7H2,1H3,(H2,13,14,15)	NDFYRGCPDAFQDG-UHFFFAOYSA-N	50055832	(1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4]dioxin-6-yl)-amine::CHEMBL308570	Alpha-2A adrenergic receptor					 8.7					ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055832&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10176999	103952313		CHEMBL308570				ZINC00020286	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50046588	COc1c(C)c(Nc2ncc[nH]2)c(C)cc1C(C)(C)C	InChI=1S/C16H23N3O/c1-10-9-12(16(3,4)5)14(20-6)11(2)13(10)19-15-17-7-8-18-15/h7-9H,1-6H3,(H2,17,18,19)	AZADEQYOIWOMER-UHFFFAOYSA-N	50055835	(4-tert-Butyl-3-methoxy-2,6-dimethyl-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL75257	Alpha-2A adrenergic receptor					>5000					ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055835&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9795515	103952316		CHEMBL75257				ZINC13760749	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50046594	Cc1c(Nc2ncc[nH]2)ccc2OCCNc12	InChI=1S/C12H14N4O/c1-8-9(16-12-14-4-5-15-12)2-3-10-11(8)13-6-7-17-10/h2-5,13H,6-7H2,1H3,(H2,14,15,16)	JDFLCCTUDMVCCS-UHFFFAOYSA-N	50055830	(1H-Imidazol-2-yl)-(5-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amine::CHEMBL432155	Alpha-2A adrenergic receptor					 124					ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055830&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9859437	103952311		CHEMBL432155				ZINC00020288	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50053290	COc1ccccc1N1CCN(C[C@@H]2CN=C3N2C(SC)=Nc2ccccc32)CC1	InChI=1S/C23H27N5OS/c1-29-21-10-6-5-9-20(21)27-13-11-26(12-14-27)16-17-15-24-22-18-7-3-4-8-19(18)25-23(30-2)28(17)22/h3-10,17H,11-16H2,1-2H3/t17-/m0/s1	DVYBIZHLZSDANU-KRWDZBQOSA-N	50455096	CHEMBL2092927	Alpha-2A adrenergic receptor		 3000								ChEMBL	10.1021/jm970159v	10.7270/Q2GM880H	9703460			Chern, JW; Tao, PL; Wang, KC; Gutcait, A; Liu, SW; Yen, MH; Chien, SL; Rong, JK	National Taiwan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455096&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9953974	225146420		CHEMBL2092927					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50050115	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)	VCKUSRYTPJJLNI-UHFFFAOYSA-N	50033111	1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine	Alpha-2A adrenergic receptor		 3702.0								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033111&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TZN	4O3F,4O33	5401	103941452	9445	CHEMBL611	DB01162	7302	C07127	ZINC01271441	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50050131	COc1cccc(OC)c1OCCNCC1COc2ccccc2O1	InChI=1S/C19H23NO5/c1-21-17-8-5-9-18(22-2)19(17)23-11-10-20-12-14-13-24-15-6-3-4-7-16(15)25-14/h3-9,14,20H,10-13H2,1-2H3	GYSZUJHYXCZAKI-UHFFFAOYSA-N	69602	2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride::CHEMBL25554::MLS000859914::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride::SMR000326775::WB-4101::WB-4101 hydrochloride::cid_11957505	Alpha-2A adrenergic receptor		 3.5								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69602&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5685	252647768	64094	CHEMBL25554				ZINC02169424	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50050137	CN1CCc2c(Cl)ccc(OCC=C(C)C)c2CC1	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3	MBYSTKNEMJZSIK-UHFFFAOYSA-N	50030623	6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL114166::SK&F-104078::SK-104078::SKF 104078	Alpha-2A adrenergic receptor		 114								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030623&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122295	103939472		CHEMBL114166				ZINC05158824	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50050153	O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccccc1	InChI=1S/C22H25N3O/c26-22(17-6-2-1-3-7-17)24-19-11-14-25(15-12-19)13-10-18-16-23-21-9-5-4-8-20(18)21/h1-9,16,19,23H,10-15H2,(H,24,26)	JXZZEXZZKAWDSP-UHFFFAOYSA-N	50033113	CHEMBL279516::INDORAMIN::INDORAMINE::INDORAMINN-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide::N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide::N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide (Indoramin)::N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide(indoramin)	Alpha-2A adrenergic receptor		 2240.0								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033113&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			33625	103941454		CHEMBL279516		501		ZINC00001567	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50050156	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 2.6								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50050172	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 2133								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50050180	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1COc2ccccc2O1	InChI=1S/C23H25N5O5/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26)	RUZYUOTYCVRMRZ-UHFFFAOYSA-N	86731	CAS_74191-85-8::Doxazosin::UK 33,274	Alpha-2A adrenergic receptor		 729								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86731&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3157	136352780			DB00590		C06970	ZINC00896512	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50050251	COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1	InChI=1S/C21H31N5O3/c1-16-19(23(2)21(28)24(3)20(16)27)22-10-7-11-25-12-14-26(15-13-25)17-8-5-6-9-18(17)29-4/h5-6,8-9,22H,7,10-15H2,1-4H3	HIHZDNKKIUQQSC-UHFFFAOYSA-N	50033112	6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propylamino}-1,3,5-trimethyl-1H-pyrimidine-2,4-dione::CHEMBL420060::Urapidil-5-methyl	Alpha-2A adrenergic receptor		 612.0								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033112&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5640	103941453		CHEMBL420060		489		ZINC02012436	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069438	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2A adrenergic receptor					 115					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069439	CC(Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)	NMSAVNXFCXMJJY-UHFFFAOYSA-N	50002904	CHEMBL222928	Alpha-2A adrenergic receptor		 60								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002904&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11361608	242056300		CHEMBL222928					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069447	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2A adrenergic receptor		 28								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069453	CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1	InChI=1S/C17H17FN2O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	OOYTZYZXCMCMSZ-UHFFFAOYSA-N	50002903	CHEMBL223836	Alpha-2A adrenergic receptor		 15								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002903&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11211035	242056299		CHEMBL223836					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069455	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2A adrenergic receptor					 316					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069467	C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m1/s1	OGOLMGZJNRNULQ-CYBMUJFWSA-N	50417353	CHEMBL242265	Alpha-2A adrenergic receptor		 186								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417353&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11043720	163366377		CHEMBL242265				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069475	C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m0/s1	OGOLMGZJNRNULQ-ZDUSSCGKSA-N	50417354	CHEMBL396013	Alpha-2A adrenergic receptor		 91								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417354&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10333157	163366378		CHEMBL396013				ZINC00009140	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069499	C[C@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	NMSAVNXFCXMJJY-LBPRGKRZSA-N	50417341	CHEMBL397753	Alpha-2A adrenergic receptor		 72								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417341&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757182	163366365		CHEMBL397753				ZINC13585595	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069503	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2A adrenergic receptor		 81								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50069512	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2A adrenergic receptor					 372					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077501	C[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C14H14N2/c1-9-10-4-2-3-5-11(10)12-6-14(9,12)13-7-15-8-16-13/h2-5,7-9,12H,6H2,1H3,(H,15,16)/t9-,12+,14+/m0/s1	VDSXZDLUEYFJGH-MRCXROJRSA-N	50417020	CHEMBL1256609	Alpha-2A adrenergic receptor		 0.218776								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417020&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781222	163366044		CHEMBL1256609				ZINC64548332	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077502	CC[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C15H16N2/c1-2-12-10-5-3-4-6-11(10)13-7-15(12,13)14-8-16-9-17-14/h3-6,8-9,12-13H,2,7H2,1H3,(H,16,17)/t12-,13+,15+/m0/s1	AKBJKOBHDJQWMB-GZBFAFLISA-N	50417013	CHEMBL1256610	Alpha-2A adrenergic receptor		 0.512861								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417013&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781223	163366037		CHEMBL1256610				ZINC64548333	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077503	CC(C)O[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C16H18N2O/c1-10(2)19-15-12-6-4-3-5-11(12)13-7-16(13,15)14-8-17-9-18-14/h3-6,8-10,13,15H,7H2,1-2H3,(H,17,18)/t13-,15+,16-/m1/s1	PNISAWOKGCKONH-VNQPRFMTSA-N	50417014	CHEMBL1256608	Alpha-2A adrenergic receptor		 46								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417014&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781008	163366038		CHEMBL1256608				ZINC64548331	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077505	CCC1(Cc2ccc(F)cc2C1)c1cnc[nH]1	InChI=1S/C14H15FN2/c1-2-14(13-8-16-9-17-13)6-10-3-4-12(15)5-11(10)7-14/h3-5,8-9H,2,6-7H2,1H3,(H,16,17)	KXSUAWAUCNFBQJ-UHFFFAOYSA-N	50417007	FIPAMEZOLE	Alpha-2A adrenergic receptor		 7.2								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417007&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			213041	163366031						ZINC05424460	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077507	C1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C13H12N2/c1-2-4-10-9(3-1)5-13(6-11(10)13)12-7-14-8-15-12/h1-4,7-8,11H,5-6H2,(H,14,15)/t11-,13+/m1/s1	FIERHAFMRVRMDV-YPMHNXCESA-N	50417006	CHEMBL1256414	Alpha-2A adrenergic receptor		 0.079								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417006&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781228	163366030		CHEMBL1256414				ZINC64549483	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077511	CCO[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C15H16N2O/c1-2-18-14-11-6-4-3-5-10(11)12-7-15(12,14)13-8-16-9-17-13/h3-6,8-9,12,14H,2,7H2,1H3,(H,16,17)/t12-,14+,15-/m1/s1	ASHFKBMVCDTQQO-VHDGCEQUSA-N	50417015	CHEMBL1256565	Alpha-2A adrenergic receptor		 3.3								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417015&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781006	163366039		CHEMBL1256565				ZINC64548361	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077513	CCCO[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C16H18N2O/c1-2-7-19-15-12-6-4-3-5-11(12)13-8-16(13,15)14-9-17-10-18-14/h3-6,9-10,13,15H,2,7-8H2,1H3,(H,17,18)/t13-,15+,16-/m1/s1	IXRPDYSTGHYEBR-VNQPRFMTSA-N	50417021	CHEMBL1256566	Alpha-2A adrenergic receptor		 4								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417021&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781007	163366045		CHEMBL1256566				ZINC64548362	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077519	CO[C@@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C14H14N2O/c1-17-13-10-5-3-2-4-9(10)11-6-14(11,13)12-7-15-8-16-12/h2-5,7-8,11,13H,6H2,1H3,(H,15,16)/t11-,13-,14-/m1/s1	HSSBMQXDKGERBI-MRVWCRGKSA-N	50417017	CHEMBL1256502	Alpha-2A adrenergic receptor		 12								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417017&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781004	163366041		CHEMBL1256502				ZINC64528359	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077529	CO[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C14H14N2O/c1-17-13-10-5-3-2-4-9(10)11-6-14(11,13)12-7-15-8-16-12/h2-5,7-8,11,13H,6H2,1H3,(H,15,16)/t11-,13+,14-/m1/s1	HSSBMQXDKGERBI-KWCYVHTRSA-N	50417016	CHEMBL1256503	Alpha-2A adrenergic receptor		 55								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417016&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781005	163366040		CHEMBL1256503				ZINC64528360	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077532	CCC[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C16H18N2/c1-2-5-13-11-6-3-4-7-12(11)14-8-16(13,14)15-9-17-10-18-15/h3-4,6-7,9-10,13-14H,2,5,8H2,1H3,(H,17,18)/t13-,14+,16+/m0/s1	LQKQCQKZRUYZOI-SQWLQELKSA-N	50417012	CHEMBL1255616	Alpha-2A adrenergic receptor		 0.851138								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417012	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417012&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781224	163366036		CHEMBL1255616				ZINC64540316	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077533	C1CC11c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C15H14N2/c1-2-4-11-10(3-1)12-7-15(12,14(11)5-6-14)13-8-16-9-17-13/h1-4,8-9,12H,5-7H2,(H,16,17)/t12-,15-/m1/s1	FYLKUCQQWYKEOG-IUODEOHRSA-N	50417011	CHEMBL1255617	Alpha-2A adrenergic receptor		 3.89								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417011&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781887	163366035		CHEMBL1255617				ZINC33961969	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077553	CC1(C)[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C15H16N2/c1-14(2)13-11-6-4-3-5-10(11)7-15(13,14)12-8-16-9-17-12/h3-6,8-9,13H,7H2,1-2H3,(H,16,17)/t13-,15+/m0/s1	JWXMKFUDAOLJCY-DZGCQCFKSA-N	50417018	CHEMBL1255770	Alpha-2A adrenergic receptor		 1.1								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417018&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52950140	163366042		CHEMBL1255770				ZINC64540324	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077554	CC[C@H]1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C15H16N2/c1-2-12-14-11-6-4-3-5-10(11)7-15(12,14)13-8-16-9-17-13/h3-6,8-9,12,14H,2,7H2,1H3,(H,16,17)/t12-,14-,15+/m0/s1	ARHWJJBPLJIHQP-AEGPPILISA-N	50417010	CHEMBL1255723	Alpha-2A adrenergic receptor		 0.138038								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417010&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52944548	163366034		CHEMBL1255723				ZINC64540975	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077555	CCC[C@H]1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C16H18N2/c1-2-5-13-15-12-7-4-3-6-11(12)8-16(13,15)14-9-17-10-18-14/h3-4,6-7,9-10,13,15H,2,5,8H2,1H3,(H,17,18)/t13-,15-,16+/m0/s1	PRXCUMHAHRIDJF-CWRNSKLLSA-N	50417009	CHEMBL1255724	Alpha-2A adrenergic receptor		 0.407380								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417009&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52948958	163366033		CHEMBL1255724				ZINC38327733	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077556	C[C@H]1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C14H14N2/c1-9-13-11-5-3-2-4-10(11)6-14(9,13)12-7-15-8-16-12/h2-5,7-9,13H,6H2,1H3,(H,15,16)/t9-,13+,14+/m0/s1	WYFCRYMMLDTJAM-CUOATXAZSA-N	50417019	CHEMBL1256378	Alpha-2A adrenergic receptor		 0.173780								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417019&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52941512	163366043		CHEMBL1256378				ZINC34484999	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077557	C[C@]12C[C@]1(Cc1ccccc21)c1cnc[nH]1	InChI=1S/C14H14N2/c1-13-8-14(13,12-7-15-9-16-12)6-10-4-2-3-5-11(10)13/h2-5,7,9H,6,8H2,1H3,(H,15,16)/t13-,14-/m1/s1	DLWKVBPPVYZEML-ZIAGYGMSSA-N	50417008	CHEMBL1255771	Alpha-2A adrenergic receptor		 0.446684								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417008&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52943739	163366032		CHEMBL1255771				ZINC64539747	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50077569	CCC1(Cc2ccccc2C1)c1cnc[nH]1	InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)	HSWPZIDYAHLZDD-UHFFFAOYSA-N	81807	ATIPAMEZOLE::CAS_104054-27-5::NSC_71310	Alpha-2A adrenergic receptor		 1.9								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81807&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71310	131342381						ZINC05424171	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50087271	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 3.8								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50087277	Cc1c(ccc2nccnc12)N=C1NCCN1	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)	QZUXRMOPAGPTIY-UHFFFAOYSA-N	50052880	CHEMBL49137::Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine	Alpha-2A adrenergic receptor		 2								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052880&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185076	103949620		CHEMBL49137				ZINC05159693	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50087279	Cc1c(ccc2NCCNc12)N=C1NCCN1	InChI=1S/C12H17N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-3,13-14H,4-7H2,1H3,(H2,15,16,17)	PGOVKWAJCVAZNG-UHFFFAOYSA-N	50052881	AGN-192172::CHEMBL49284::Imidazolidin-2-ylidene-(5-methyl-1,2,3,4-tetrahydro-quinoxalin-6-yl)-amine	Alpha-2A adrenergic receptor		 9.6								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052881&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816048	103949621		CHEMBL49284				ZINC13757898	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50087282	Nc1cc(Cl)c(N=C2NCCN2)c(Cl)c1	InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15)	IEJXVRYNEISIKR-UHFFFAOYSA-N	50021812	2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine::2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine (p-aminoclonidine)::2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine(p-Aminoclonidine)::APRACLONIDINE::CHEMBL647::P-AMINOCLONIDINE2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine	Alpha-2A adrenergic receptor		 2.9								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021812&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2216	103932510	2788	CHEMBL647		7117		ZINC00057175	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50087299	Cc1c(ccc2OCCNc12)N=C1NCCN1	InChI=1S/C12H16N4O/c1-8-9(16-12-14-4-5-15-12)2-3-10-11(8)13-6-7-17-10/h2-3,13H,4-7H2,1H3,(H2,14,15,16)	OSJZLDGTMVBIRV-UHFFFAOYSA-N	50052882	AGN-193080::CHEMBL298936::Imidazolidin-2-ylidene-(5-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amine	Alpha-2A adrenergic receptor		 1.2								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052882&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9837551	103949622		CHEMBL298936				ZINC00006307	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093092	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2A adrenergic receptor					 4.1					ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093098	COc1ccc(Nc2ncc[nH]2)c(C)c1	InChI=1S/C11H13N3O/c1-8-7-9(15-2)3-4-10(8)14-11-12-5-6-13-11/h3-7H,1-2H3,(H2,12,13,14)	BEAKKNUWBXQLLR-UHFFFAOYSA-N	50055827	(1H-Imidazol-2-yl)-(4-methoxy-2-methyl-phenyl)-amine::CHEMBL77913	Alpha-2A adrenergic receptor		 10								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055827&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10198135	103952308		CHEMBL77913				ZINC00020287	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093108	Brc1ccccc1Nc1ncc[nH]1	InChI=1S/C9H8BrN3/c10-7-3-1-2-4-8(7)13-9-11-5-6-12-9/h1-6H,(H2,11,12,13)	KHNAVCNEASQADL-UHFFFAOYSA-N	50055833	(2-Bromo-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL76457	Alpha-2A adrenergic receptor		 210								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055833&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10490084	103952314		CHEMBL76457				ZINC13760746	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093109	COc1ccc(Nc2ncc[nH]2)c(C)c1OC	InChI=1S/C12H15N3O2/c1-8-9(15-12-13-6-7-14-12)4-5-10(16-2)11(8)17-3/h4-7H,1-3H3,(H2,13,14,15)	AMBHHYSUKMHFDB-UHFFFAOYSA-N	50055834	(3,4-Dimethoxy-2-methyl-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL308863	Alpha-2A adrenergic receptor		 130								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055834&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10609673	103952315		CHEMBL308863				ZINC13760748	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093115	N(c1ncc[nH]1)c1ccc2nc[nH]c2c1	InChI=1S/C10H9N5/c1-2-8-9(14-6-13-8)5-7(1)15-10-11-3-4-12-10/h1-6H,(H,13,14)(H2,11,12,15)	NFSIDEIKDWWMOX-UHFFFAOYSA-N	50055831	(1H-Benzoimidazol-5-yl)-(1H-imidazol-2-yl)-amine::CHEMBL74544	Alpha-2A adrenergic receptor		 76								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055831&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10655607	103952312		CHEMBL74544				ZINC13760751	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093118	Cc1c(Nc2ncc[nH]2)ccc2OCCNc12	InChI=1S/C12H14N4O/c1-8-9(16-12-14-4-5-15-12)2-3-10-11(8)13-6-7-17-10/h2-5,13H,6-7H2,1H3,(H2,14,15,16)	JDFLCCTUDMVCCS-UHFFFAOYSA-N	50055830	(1H-Imidazol-2-yl)-(5-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amine::CHEMBL432155	Alpha-2A adrenergic receptor		 6								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055830&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9859437	103952311		CHEMBL432155				ZINC00020288	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093129	Cc1c(Nc2ncc[nH]2)ccc2nccnc12	InChI=1S/C12H11N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-7H,1H3,(H2,15,16,17)	AEWIKTWIKIWVNJ-UHFFFAOYSA-N	50055829	(1H-Imidazol-2-yl)-(5-methyl-quinoxalin-6-yl)-amine::CHEMBL75491	Alpha-2A adrenergic receptor		 31								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055829&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9794524	103952310		CHEMBL75491				ZINC00020289	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093133	Cc1c(ccc2nccnc12)N=C1NCCN1	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)	QZUXRMOPAGPTIY-UHFFFAOYSA-N	50052880	CHEMBL49137::Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine	Alpha-2A adrenergic receptor		 2								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052880&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185076	103949620		CHEMBL49137				ZINC05159693	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093139	COc1cc(C)c(Nc2ncc[nH]2)cc1C(C)(C)C	InChI=1S/C15H21N3O/c1-10-8-13(19-5)11(15(2,3)4)9-12(10)18-14-16-6-7-17-14/h6-9H,1-5H3,(H2,16,17,18)	QELYRGGNEIAOKD-UHFFFAOYSA-N	50055837	(5-tert-Butyl-4-methoxy-2-methyl-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL78190	Alpha-2A adrenergic receptor		 39								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055837&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10682720	103952318		CHEMBL78190				ZINC13760750	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093140	Cc1c(Nc2ncc[nH]2)ccc2OCCOc12	InChI=1S/C12H13N3O2/c1-8-9(15-12-13-4-5-14-12)2-3-10-11(8)17-7-6-16-10/h2-5H,6-7H2,1H3,(H2,13,14,15)	NDFYRGCPDAFQDG-UHFFFAOYSA-N	50055832	(1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4]dioxin-6-yl)-amine::CHEMBL308570	Alpha-2A adrenergic receptor		 1.7								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055832&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10176999	103952313		CHEMBL308570				ZINC00020286	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093141	N(c1ncc[nH]1)c1ccc2nccnc2c1	InChI=1S/C11H9N5/c1-2-9-10(13-4-3-12-9)7-8(1)16-11-14-5-6-15-11/h1-7H,(H2,14,15,16)	CDFWKVORAWOKDO-UHFFFAOYSA-N	50055838	(1H-Imidazol-2-yl)-quinoxalin-6-yl-amine::CHEMBL74449	Alpha-2A adrenergic receptor		 3100								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055838&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10632290	103952319		CHEMBL74449				ZINC13760747	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093148	Brc1c(Nc2ncc[nH]2)ccc2nccnc12	InChI=1S/C11H8BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-6H,(H2,15,16,17)	FJXZFBTUCZEINA-UHFFFAOYSA-N	50055828	(5-Bromo-quinoxalin-6-yl)-(1H-imidazol-2-yl)-amine::CHEMBL1019	Alpha-2A adrenergic receptor		 510								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055828&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10214826	103952309		CHEMBL1019				ZINC13760745	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093154	Clc1cccc(Cl)c1Nc1ncc[nH]1	InChI=1S/C9H7Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-5H,(H2,12,13,14)	JMIQFISPBOHMQG-UHFFFAOYSA-N	50055836	(2,6-Dichloro-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL1022	Alpha-2A adrenergic receptor		 95								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055836&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10489502	103952317		CHEMBL1022				ZINC03820959	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50093159	COc1c(C)c(Nc2ncc[nH]2)c(C)cc1C(C)(C)C	InChI=1S/C16H23N3O/c1-10-9-12(16(3,4)5)14(20-6)11(2)13(10)19-15-17-7-8-18-15/h7-9H,1-6H3,(H2,17,18,19)	AZADEQYOIWOMER-UHFFFAOYSA-N	50055835	(4-tert-Butyl-3-methoxy-2,6-dimethyl-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL75257	Alpha-2A adrenergic receptor		 4.9								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055835&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9795515	103952316		CHEMBL75257				ZINC13760749	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50103001	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)	VCKUSRYTPJJLNI-UHFFFAOYSA-N	50033111	1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine	Alpha-2A adrenergic receptor		 1500								ChEMBL	10.1021/jm970364a	10.7270/Q2R78DBB	9379432			Meyer, MD; Altenbach, RJ; Basha, FZ; Carroll, WA; Drizin, I; Elmore, SW; Ehrlich, PP; Lebold, SA; Tietje, K; Sippy, KB; Wendt, MD; Plata, DJ; Plagge, F; Buckner, SA; Brune, ME; Hancock, AA; Kerwin, JF	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033111&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TZN	4O3F,4O33	5401	103941452	9445	CHEMBL611	DB01162	7302	C07127	ZINC01271441	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50103003	COc1cccc2[C@@H]3CN(CCn4c(=O)[nH]c5c6ncccc6sc5c4=O)C[C@@H]3CCc12	InChI=1S/C24H24N4O3S/c1-31-18-5-2-4-15-16(18)8-7-14-12-27(13-17(14)15)10-11-28-23(29)22-21(26-24(28)30)20-19(32-22)6-3-9-25-20/h2-6,9,14,17H,7-8,10-13H2,1H3,(H,26,30)/t14-,17+/m0/s1	OLPQNRLJYOGSGV-WMLDXEAASA-N	50060965	2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione::2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,6-triaza-fluorene-1,3-dione::2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione::A-131701::CHEMBL40650	Alpha-2A adrenergic receptor		 94.9								ChEMBL	10.1021/jm970364a	10.7270/Q2R78DBB	9379432			Meyer, MD; Altenbach, RJ; Basha, FZ; Carroll, WA; Drizin, I; Elmore, SW; Ehrlich, PP; Lebold, SA; Tietje, K; Sippy, KB; Wendt, MD; Plata, DJ; Plagge, F; Buckner, SA; Brune, ME; Hancock, AA; Kerwin, JF	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060965&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10527469	103956571		CHEMBL40650				ZINC25422025	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50103009	CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O	InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1	DRHKJLXJIQTDTD-OAHLLOKOSA-N	50060964	(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide::5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide::5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide::CHEMBL836::TAMSULOSIN	Alpha-2A adrenergic receptor		 13.4								ChEMBL	10.1021/jm970364a	10.7270/Q2R78DBB	9379432			Meyer, MD; Altenbach, RJ; Basha, FZ; Carroll, WA; Drizin, I; Elmore, SW; Ehrlich, PP; Lebold, SA; Tietje, K; Sippy, KB; Wendt, MD; Plata, DJ; Plagge, F; Buckner, SA; Brune, ME; Hancock, AA; Kerwin, JF	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060964&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	JGX		129211	103956570	9398	CHEMBL836	DB00706	488	C07124	ZINC01530694	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50101482	C(CN1CCN(CC1)c1ncccn1)Cc1nc2ccccc2s1	InChI=1S/C18H21N5S/c1-2-6-16-15(5-1)21-17(24-16)7-3-10-22-11-13-23(14-12-22)18-19-8-4-9-20-18/h1-2,4-6,8-9H,3,7,10-14H2	PQVQCEDGSJVHMK-UHFFFAOYSA-N	50017964	CHEMBL3289656	Alpha-2A adrenergic receptor		 844								ChEMBL	10.1016/j.bmc.2014.04.026	10.7270/Q25140RW	24800940			Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017964&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56852956	242041856		CHEMBL3289656					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106946	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2A adrenergic receptor		 1.9								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106948	Cl.Clc1cccc(Cl)c1NC1=NCCN1	InChI=1S/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-3H,4-5H2,(H2,12,13,14);1H	ZNIFSRGNXRYGHF-UHFFFAOYSA-N	50020341	CLONIDINE HYDROCHLORIDE::Catapres::Clonidine HCl::Dichloranilino Imidazolin::Duraclon::Jenloga::Kapvay::ST-155	Alpha-2A adrenergic receptor		 21								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020341&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			20179	103931244						ZINC34800555	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106949	Cl.CCOc1ccc(cc1)\N=C(\N)NCc1ccco1	InChI=1S/C14H17N3O2.ClH/c1-2-18-12-7-5-11(6-8-12)17-14(15)16-10-13-4-3-9-19-13;/h3-9H,2,10H2,1H3,(H3,15,16,17);1H	ZRHPKUGCNPEIRD-UHFFFAOYSA-N	50020342	CHEMBL3289533	Alpha-2A adrenergic receptor		 1479								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644701	103931245		CHEMBL3289533				ZINC36272139	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106953	Cl.CN(C)c1ccc(cc1)\N=C(\N)NCc1ccco1	InChI=1S/C14H18N4O.ClH/c1-18(2)12-7-5-11(6-8-12)17-14(15)16-10-13-4-3-9-19-13;/h3-9H,10H2,1-2H3,(H3,15,16,17);1H	SHJXYQBFRUAPGL-UHFFFAOYSA-N	50020343	CHEMBL3289532	Alpha-2A adrenergic receptor		 214								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020343&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644703	103931246		CHEMBL3289532		6560			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106955	Cl.N=C(NCc1ccco1)Nc1ccc2CCCCc2c1	InChI=1S/C16H19N3O.ClH/c17-16(18-11-15-6-3-9-20-15)19-14-8-7-12-4-1-2-5-13(12)10-14;/h3,6-10H,1-2,4-5,11H2,(H3,17,18,19);1H	PMPMJRVSXCBXSU-UHFFFAOYSA-N	50020344	CHEMBL3289531	Alpha-2A adrenergic receptor		 513								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020344&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644705	103931247		CHEMBL3289531					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106958	Cl.CCNc1ccc(cc1)\N=C(\N)NCc1ccco1	InChI=1S/C14H18N4O.ClH/c1-2-16-11-5-7-12(8-6-11)18-14(15)17-10-13-4-3-9-19-13;/h3-9,16H,2,10H2,1H3,(H3,15,17,18);1H	CDWGODXWRCYFRB-UHFFFAOYSA-N	50020345	CHEMBL3289530	Alpha-2A adrenergic receptor		 1072								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020345&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644707	103931248		CHEMBL3289530					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106959	Cl.N=C(NCc1ccco1)Nc1ccc2OCOc2c1	InChI=1S/C13H13N3O3.ClH/c14-13(15-7-10-2-1-5-17-10)16-9-3-4-11-12(6-9)19-8-18-11;/h1-6H,7-8H2,(H3,14,15,16);1H	JBABDPFUVYDFIL-UHFFFAOYSA-N	50020346	CHEMBL3289529	Alpha-2A adrenergic receptor		 1514								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644709	103931249		CHEMBL3289529					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106961	CCOc1ccc(NC(=N)NCCO)cc1	InChI=1S/C11H17N3O2.ClH/c1-2-16-10-5-3-9(4-6-10)14-11(12)13-7-8-15;/h3-6,15H,2,7-8H2,1H3,(H3,12,13,14);1H	DMTIMWXGYOATLY-UHFFFAOYSA-N	50020347	CHEMBL3289528	Alpha-2A adrenergic receptor		 19055								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644711	242042143		CHEMBL3289528					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106962	CN(C)c1ccc(NC(=N)NCCO)cc1	InChI=1S/C11H18N4O.ClH/c1-15(2)10-5-3-9(4-6-10)14-11(12)13-7-8-16;/h3-6,16H,7-8H2,1-2H3,(H3,12,13,14);1H	XETMIJLWVYUCFF-UHFFFAOYSA-N	50020348	CHEMBL3289527	Alpha-2A adrenergic receptor		 1862								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020348&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644713	242042144		CHEMBL3289527					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106963	OCCNC(=N)Nc1ccc2CCCCc2c1	InChI=1S/C13H19N3O.ClH/c14-13(15-7-8-17)16-12-6-5-10-3-1-2-4-11(10)9-12;/h5-6,9,17H,1-4,7-8H2,(H3,14,15,16);1H	MLWZBUNYFVNOLO-UHFFFAOYSA-N	50020349	CHEMBL3289526	Alpha-2A adrenergic receptor		 1738								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020349&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644715	242042145		CHEMBL3289526					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106964	CCNc1ccc(NC(=N)NCCO)cc1	InChI=1S/C11H18N4O.ClH/c1-2-13-9-3-5-10(6-4-9)15-11(12)14-7-8-16;/h3-6,13,16H,2,7-8H2,1H3,(H3,12,14,15);1H	VEDRAPBMHNMBRV-UHFFFAOYSA-N	50020350	CHEMBL3289525	Alpha-2A adrenergic receptor		 18621								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020350&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644717	242042146		CHEMBL3289525					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106967	OCCNC(=N)Nc1ccc2OCOc2c1	InChI=1S/C10H13N3O3.ClH/c11-10(12-3-4-14)13-7-1-2-8-9(5-7)16-6-15-8;/h1-2,5,14H,3-4,6H2,(H3,11,12,13);1H	PPIFNZRSPNWNQV-UHFFFAOYSA-N	50020351	CHEMBL3289524	Alpha-2A adrenergic receptor		 11749								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644719	242042147		CHEMBL3289524					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106968	CCOc1ccc(NC(=N)Nc2ccccc2)cc1	InChI=1S/C15H17N3O.ClH/c1-2-19-14-10-8-13(9-11-14)18-15(16)17-12-6-4-3-5-7-12;/h3-11H,2H2,1H3,(H3,16,17,18);1H	WVYDXXNNFNXHIE-UHFFFAOYSA-N	50020352	CHEMBL3289523	Alpha-2A adrenergic receptor		 2239								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020352&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644721	242042148		CHEMBL3289523					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106969	CN(C)c1ccc(NC(=N)Nc2ccccc2)cc1	InChI=1S/C15H18N4.ClH/c1-19(2)14-10-8-13(9-11-14)18-15(16)17-12-6-4-3-5-7-12;/h3-11H,1-2H3,(H3,16,17,18);1H	ZOLNZLROPVNOJS-UHFFFAOYSA-N	50020353	CHEMBL3289522	Alpha-2A adrenergic receptor		 389								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020353&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644723	242042149		CHEMBL3289522					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106970	CC1CN\C(N1)=N\c1ccc(cc1)N(C)C	InChI=1S/C12H18N4.ClH/c1-9-8-13-12(14-9)15-10-4-6-11(7-5-10)16(2)3;/h4-7,9H,8H2,1-3H3,(H2,13,14,15);1H	MDUBJOQRFFHUQI-UHFFFAOYSA-N	50020354	CHEMBL3289542	Alpha-2A adrenergic receptor		 3311								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020354&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644725	242042150		CHEMBL3289542					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106971	CC1CN\C(N1)=N\c1ccc2CCCCc2c1	InChI=1S/C14H19N3.ClH/c1-10-9-15-14(16-10)17-13-7-6-11-4-2-3-5-12(11)8-13;/h6-8,10H,2-5,9H2,1H3,(H2,15,16,17);1H	ZAGJVWVJTZWYPQ-UHFFFAOYSA-N	50020355	CHEMBL3289543	Alpha-2A adrenergic receptor		 1000								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020355&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644727	242042151		CHEMBL3289543					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106972	CCNc1ccc(cc1)\N=C1\NCC(C)N1	InChI=1S/C12H18N4.ClH/c1-3-13-10-4-6-11(7-5-10)16-12-14-8-9(2)15-12;/h4-7,9,13H,3,8H2,1-2H3,(H2,14,15,16);1H	KPSLZKAMRMMBDB-UHFFFAOYSA-N	50020356	CHEMBL3289544	Alpha-2A adrenergic receptor		 12303								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020356&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644729	242042152		CHEMBL3289544					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106973	CC1CN\C(N1)=N\c1ccc2OCOc2c1	InChI=1S/C11H13N3O2.ClH/c1-7-5-12-11(13-7)14-8-2-3-9-10(4-8)16-6-15-9;/h2-4,7H,5-6H2,1H3,(H2,12,13,14);1H	WXUUSQYWSZPBGZ-UHFFFAOYSA-N	50020357	CHEMBL3289545	Alpha-2A adrenergic receptor		 2344								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020357&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644731	242042153		CHEMBL3289545					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106974	CCOc1ccc(cc1)\N=C1\NCC(N1)c1ccco1	InChI=1S/C15H17N3O2.ClH/c1-2-19-12-7-5-11(6-8-12)17-15-16-10-13(18-15)14-4-3-9-20-14;/h3-9,13H,2,10H2,1H3,(H2,16,17,18);1H	HRGUXTJNVDIPQL-UHFFFAOYSA-N	50020358	CHEMBL3289546	Alpha-2A adrenergic receptor		 2630								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020358&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644733	242042154		CHEMBL3289546					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106975	CN(C)c1ccc(cc1)\N=C1\NCC(N1)c1ccco1	InChI=1S/C15H18N4O.ClH/c1-19(2)12-7-5-11(6-8-12)17-15-16-10-13(18-15)14-4-3-9-20-14;/h3-9,13H,10H2,1-2H3,(H2,16,17,18);1H	UUEFLQROTZFXTN-UHFFFAOYSA-N	50020359	CHEMBL3289547	Alpha-2A adrenergic receptor		 1318								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020359&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644735	242042155		CHEMBL3289547					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106976	C1N\C(NC1c1ccco1)=N\c1ccc2CCCCc2c1	InChI=1S/C17H19N3O.ClH/c1-2-5-13-10-14(8-7-12(13)4-1)19-17-18-11-15(20-17)16-6-3-9-21-16;/h3,6-10,15H,1-2,4-5,11H2,(H2,18,19,20);1H	OIEWSIVPYWQCOP-UHFFFAOYSA-N	50020360	CHEMBL3289548	Alpha-2A adrenergic receptor		 692								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020360&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644737	242042156		CHEMBL3289548					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106977	CCNc1ccc(cc1)\N=C1\NCC(N1)c1ccco1	InChI=1S/C15H18N4O.ClH/c1-2-16-11-5-7-12(8-6-11)18-15-17-10-13(19-15)14-4-3-9-20-14;/h3-9,13,16H,2,10H2,1H3,(H2,17,18,19);1H	WERYBTQUCQUDCE-UHFFFAOYSA-N	50020361	CHEMBL3289549	Alpha-2A adrenergic receptor		 2188								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020361&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644739	242042157		CHEMBL3289549					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106978	C1Oc2ccc(cc2O1)\N=C1\NCC(N1)c1ccco1	InChI=1S/C14H13N3O3.ClH/c1-2-11(18-5-1)10-7-15-14(17-10)16-9-3-4-12-13(6-9)20-8-19-12;/h1-6,10H,7-8H2,(H2,15,16,17);1H	BZIVDSMEJMWSQX-UHFFFAOYSA-N	50020362	CHEMBL3289550	Alpha-2A adrenergic receptor		 1698								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020362&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644741	242042158		CHEMBL3289550					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106979	CCOc1ccc(cc1)N=C1NCCN1	InChI=1S/C11H15N3O.ClH/c1-2-15-10-5-3-9(4-6-10)14-11-12-7-8-13-11;/h3-6H,2,7-8H2,1H3,(H2,12,13,14);1H	GBPVUVKJUIYUPQ-UHFFFAOYSA-N	50020363	CHEMBL3289551	Alpha-2A adrenergic receptor		 79								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020363&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644743	242042159		CHEMBL3289551					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106980	N=C(Nc1ccccc1)Nc1ccc2CCCCc2c1	InChI=1S/C17H19N3.ClH/c18-17(19-15-8-2-1-3-9-15)20-16-11-10-13-6-4-5-7-14(13)12-16;/h1-3,8-12H,4-7H2,(H3,18,19,20);1H	WAUSLDUEFHDZSA-UHFFFAOYSA-N	50020364	CHEMBL3289521	Alpha-2A adrenergic receptor		 263								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020364&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644745	242042160		CHEMBL3289521					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106981	CCNc1ccc(NC(=N)Nc2ccccc2)cc1	InChI=1S/C15H18N4.ClH/c1-2-17-12-8-10-14(11-9-12)19-15(16)18-13-6-4-3-5-7-13;/h3-11,17H,2H2,1H3,(H3,16,18,19);1H	ZJOQMWPNIJZSSX-UHFFFAOYSA-N	50020365	CHEMBL3289520	Alpha-2A adrenergic receptor		 4898								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020365&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644747	242042161		CHEMBL3289520					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106982	N=C(Nc1ccccc1)Nc1ccc2OCOc2c1	InChI=1S/C14H13N3O2.ClH/c15-14(16-10-4-2-1-3-5-10)17-11-6-7-12-13(8-11)19-9-18-12;/h1-8H,9H2,(H3,15,16,17);1H	PEUSQEIXVSXYLG-UHFFFAOYSA-N	50020366	CHEMBL3289534	Alpha-2A adrenergic receptor		 4365								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020366&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644749	242042162		CHEMBL3289534					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106983	CCCNC(=N)Nc1ccc(OCC)cc1	InChI=1S/C12H19N3O.ClH/c1-3-9-14-12(13)15-10-5-7-11(8-6-10)16-4-2;/h5-8H,3-4,9H2,1-2H3,(H3,13,14,15);1H	NZLPWSJSIXEENN-UHFFFAOYSA-N	50020367	CHEMBL3289535	Alpha-2A adrenergic receptor		 4266								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020367&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644750	242042163		CHEMBL3289535					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106984	CCCNC(=N)Nc1ccc(cc1)N(C)C	InChI=1S/C12H20N4.ClH/c1-4-9-14-12(13)15-10-5-7-11(8-6-10)16(2)3;/h5-8H,4,9H2,1-3H3,(H3,13,14,15);1H	LRKIQDINEWMTDP-UHFFFAOYSA-N	50020369	CHEMBL3289536	Alpha-2A adrenergic receptor		 1122								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020369&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644751	242042164		CHEMBL3289536					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106985	CCCNC(=N)Nc1ccc2CCCCc2c1	InChI=1S/C14H21N3.ClH/c1-2-9-16-14(15)17-13-8-7-11-5-3-4-6-12(11)10-13;/h7-8,10H,2-6,9H2,1H3,(H3,15,16,17);1H	ODURLPUYPXNJAO-UHFFFAOYSA-N	50020370	CHEMBL3289537	Alpha-2A adrenergic receptor		 676								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020370&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644752	242042165		CHEMBL3289537					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106986	CCCNC(=N)Nc1ccc(NCC)cc1	InChI=1S/C12H20N4.ClH/c1-3-9-15-12(13)16-11-7-5-10(6-8-11)14-4-2;/h5-8,14H,3-4,9H2,1-2H3,(H3,13,15,16);1H	GFJMOGQIWSOGNJ-UHFFFAOYSA-N	50020371	CHEMBL3289538	Alpha-2A adrenergic receptor		 8318								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020371&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644754	242042166		CHEMBL3289538					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106987	CCCNC(=N)Nc1ccc2OCOc2c1	InChI=1S/C11H15N3O2.ClH/c1-2-5-13-11(12)14-8-3-4-9-10(6-8)16-7-15-9;/h3-4,6H,2,5,7H2,1H3,(H3,12,13,14);1H	GPDNQQZURDHKBK-UHFFFAOYSA-N	50020372	CHEMBL3289539	Alpha-2A adrenergic receptor		 15136								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020372&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644756	242042167		CHEMBL3289539					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106988	CCOc1ccc(NC(N)=N)cc1	InChI=1S/C9H13N3O.ClH/c1-2-13-8-5-3-7(4-6-8)12-9(10)11;/h3-6H,2H2,1H3,(H4,10,11,12);1H	NABVWODTBYCLMT-UHFFFAOYSA-N	50020373	CHEMBL3289540	Alpha-2A adrenergic receptor		 141								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020373&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56729561	242042168		CHEMBL3289540					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50106989	CCOc1ccc(cc1)\N=C1\NCC(C)N1	InChI=1S/C12H17N3O.ClH/c1-3-16-11-6-4-10(5-7-11)15-12-13-8-9(2)14-12;/h4-7,9H,3,8H2,1-2H3,(H2,13,14,15);1H	ZFZCWADKJZJKAB-UHFFFAOYSA-N	50020374	CHEMBL3289541	Alpha-2A adrenergic receptor		 14125								ChEMBL	10.1016/j.ejmech.2014.05.057	10.7270/Q25M6784	24908653			O'Donovan, DH; Muguruza, C; Callado, LF; Rozas, I	Trinity College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020374&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90644757	242042169		CHEMBL3289541					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50118764	CNC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(C(=O)OC)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C32H39N5O6/c1-21-26(29(38)33-3)28(23-11-13-25(14-12-23)37(41)42)27(22(2)35-21)30(39)34-17-8-18-36-19-15-32(16-20-36,31(40)43-4)24-9-6-5-7-10-24/h5-7,9-14,26,28H,8,15-20H2,1-4H3,(H,33,38)(H,34,39)	AGNYFINNIVFBHA-UHFFFAOYSA-N	50068818	1-(3-{[2,6-Dimethyl-5-methylcarbamoyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3-carbonyl]-amino}-propyl)-4-phenyl-piperidine-4-carboxylic acid methyl ester::CHEMBL147077	Alpha-2A adrenergic receptor		 760								ChEMBL	10.1021/jm980506g	10.7270/Q2R78DCS	9857099			Nagarathnam, D; Wetzel, JM; Miao, SW; Marzabadi, MR; Chiu, G; Wong, WC; Hong, X; Fang, J; Forray, C; Branchek, TA; Heydorn, WE; Chang, RS; Broten, T; Schorn, TW; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068818&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53641825	103962996		CHEMBL147077				ZINC27563665	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127397	COc1ccc2C3=NO[C@@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)[C@@H]3C=Cc2c1	InChI=1S/C28H29N3O2/c1-32-24-9-11-25-23(17-24)8-10-26-27(33-29-28(25)26)19-31-14-12-30(13-15-31)18-20-6-7-21-4-2-3-5-22(21)16-20/h2-11,16-17,26-27H,12-15,18-19H2,1H3/t26-,27-/m0/s1	UAHLUVNKSWGJEK-SVBPBHIXSA-N	50024310	CHEMBL2112972	Alpha-2A adrenergic receptor		 1.8								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024310&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71461647	277286510		CHEMBL2112972					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127402	CCNC(=O)N1C[C@H]2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C27H33N5O2/c1-2-28-27(33)32-19-23-25(34-29-26(23)22-12-6-7-13-24(22)32)20-31-17-15-30(16-18-31)14-8-11-21-9-4-3-5-10-21/h3-13,23,25H,2,14-20H2,1H3,(H,28,33)/b11-8+/t23-,25-/m0/s1	SPMYVDNOOYXROZ-BSNUYDGMSA-N	50024311	CHEMBL2112973	Alpha-2A adrenergic receptor		 20								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024311&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11224953	277286511		CHEMBL2112973					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127411	COc1cc2NC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H34N4O3/c1-19(20-7-5-4-6-8-20)9-10-30-11-13-31(14-12-30)18-26-22-17-28-23-16-25(33-3)24(32-2)15-21(23)27(22)29-34-26/h4-9,15-16,22,26,28H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	MNYRTHFYWWGGTK-WDAWEKNVSA-N	50024313	CHEMBL2112971	Alpha-2A adrenergic receptor		 6.5								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024313&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11236591	277286513		CHEMBL2112971					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127412	COc1cc2NC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H32N4O3/c1-33-25-14-22-24(15-26(25)34-2)29-16-23-27(35-30-28(22)23)18-32-11-9-31(10-12-32)17-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27,29H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	UYRONJVHVBKEPX-HOFKKMOUSA-N	50024318	CHEMBL2112976	Alpha-2A adrenergic receptor		 74								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024318&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71458044	103934524		CHEMBL2112976				ZINC27766986	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127414	COc1cc2N(C)C[C@H]3[C@H](CN4CCN(CCC\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C30H40N4O3/c1-22(17-23-10-6-5-7-11-23)9-8-12-33-13-15-34(16-14-33)21-29-25-20-32(2)26-19-28(36-4)27(35-3)18-24(26)30(25)31-37-29/h5-7,10-11,17-19,25,29H,8-9,12-16,20-21H2,1-4H3/b22-17+/t25-,29-/m0/s1	JKWINILVOXJHQG-WTVFRJDWSA-N	50024319	CHEMBL2112977	Alpha-2A adrenergic receptor		 11								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024319&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456238	103934525		CHEMBL2112977				ZINC27851984	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127415	COc1cc2NC[C@H]3[C@H](CN4CCN(Cc5ccc(Cl)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C24H29ClN4O3/c1-30-21-11-18-20(12-22(21)31-2)26-13-19-23(32-27-24(18)19)15-29-9-7-28(8-10-29)14-16-3-5-17(25)6-4-16/h3-6,11-12,19,23,26H,7-10,13-15H2,1-2H3/t19-,23-/m0/s1	DPWMWVBVQVDTJY-CVDCTZTESA-N	50024308	CHEMBL2112974	Alpha-2A adrenergic receptor		>1000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024308&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11385548	277286508		CHEMBL2112974					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127417	CCOC(=O)N1C[C@H]2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C27H32N4O3/c1-2-33-27(32)31-19-23-25(34-28-26(23)22-12-6-7-13-24(22)31)20-30-17-15-29(16-18-30)14-8-11-21-9-4-3-5-10-21/h3-13,23,25H,2,14-20H2,1H3/b11-8+/t23-,25-/m0/s1	CHKGJSUYXRACOM-BSNUYDGMSA-N	50024309	CHEMBL2112975	Alpha-2A adrenergic receptor		 33								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024309&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11385652	277286509		CHEMBL2112975					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127425	COc1cc2NC[C@H]3[C@H](CN4CCN(CCOc5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31FN4O4/c1-31-22-13-19-21(14-23(22)32-2)27-15-20-24(34-28-25(19)20)16-30-9-7-29(8-10-30)11-12-33-18-5-3-17(26)4-6-18/h3-6,13-14,20,24,27H,7-12,15-16H2,1-2H3/t20-,24-/m0/s1	AIWNTZODSQLIEU-RDPSFJRHSA-N	50024314	CHEMBL2112969	Alpha-2A adrenergic receptor		 9.1								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024314&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11431359	103934520		CHEMBL2112969				ZINC26398071	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127455	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2A adrenergic receptor		 2.6								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127612	C(\C=C\c1ccccc1)N1CCN(C[C@@H]2ON=C3[C@H]2COc2ccccc32)CC1	InChI=1S/C24H27N3O2/c1-2-7-19(8-3-1)9-6-12-26-13-15-27(16-14-26)17-23-21-18-28-22-11-5-4-10-20(22)24(21)25-29-23/h1-11,21,23H,12-18H2/b9-6+/t21-,23-/m0/s1	MUUSOYWTPTTZII-BASMTRSQSA-N	50024316	CHEMBL2112978	Alpha-2A adrenergic receptor		 0.900000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024316&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71450907	103934522		CHEMBL2112978				ZINC06019738	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127615	COc1cc2NC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H32N4O3/c1-31-23-15-20-22(16-24(23)32-2)27-17-21-25(33-28-26(20)21)18-30-13-11-29(12-14-30)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25,27H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	XWFFXPGAYIJUAN-ZPWQMVEJSA-N	50024302	CHEMBL2112983	Alpha-2A adrenergic receptor		 7.9								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024302&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11224687	277286502		CHEMBL2112983					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127616	C([C@@H]1ON=C2[C@H]1CNc1ccccc21)N1CCN(Cc2ccc3ccccc3c2)CC1	InChI=1S/C26H28N4O/c1-2-6-21-15-19(9-10-20(21)5-1)17-29-11-13-30(14-12-29)18-25-23-16-27-24-8-4-3-7-22(24)26(23)28-31-25/h1-10,15,23,25,27H,11-14,16-18H2/t23-,25-/m0/s1	WUSIUKLVFNJEHL-ZCYQVOJMSA-N	50024303	CHEMBL2112984	Alpha-2A adrenergic receptor		 4								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024303&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71454490	277286503		CHEMBL2112984					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127617	C(\C=C\c1ccccc1)N1CCN(C[C@@H]2ON=C3[C@H]2CNc2ccccc32)CC1	InChI=1S/C24H28N4O/c1-2-7-19(8-3-1)9-6-12-27-13-15-28(16-14-27)18-23-21-17-25-22-11-5-4-10-20(22)24(21)26-29-23/h1-11,21,23,25H,12-18H2/b9-6+/t21-,23-/m0/s1	HCMWMLSNHRNVSJ-BASMTRSQSA-N	50024304	CHEMBL2112981	Alpha-2A adrenergic receptor		 20								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024304&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11486051	277286504		CHEMBL2112981					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127618	COc1ccc2C3=NO[C@@H](CN4CCN(C\C=C\c5ccccc5)CC4)[C@@H]3C=Cc2c1	InChI=1S/C26H29N3O2/c1-30-22-10-12-23-21(18-22)9-11-24-25(31-27-26(23)24)19-29-16-14-28(15-17-29)13-5-8-20-6-3-2-4-7-20/h2-12,18,24-25H,13-17,19H2,1H3/b8-5+/t24-,25-/m0/s1	SATXLDNXPGMNQI-AIDJPXSQSA-N	50024305	CHEMBL2112982	Alpha-2A adrenergic receptor		 1.8								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024305&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456240	277286505		CHEMBL2112982					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127619	COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	XHLHZPFSBCZVEA-HOFKKMOUSA-N	50131351	(3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860	Alpha-2A adrenergic receptor		 1.3								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324737	104022535		CHEMBL92860				ZINC22445308	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127621	COc1cc2NC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H34N4O3/c1-19(13-20-7-5-4-6-8-20)17-30-9-11-31(12-10-30)18-26-22-16-28-23-15-25(33-3)24(32-2)14-21(23)27(22)29-34-26/h4-8,13-15,22,26,28H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JODRRUQCPGURFJ-FSTMKDAKSA-N	50024301	CHEMBL2112985	Alpha-2A adrenergic receptor		 2.4								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024301&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11202065	277286501		CHEMBL2112985					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127622	COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	XHLHZPFSBCZVEA-HOFKKMOUSA-N	50131351	(3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860	Alpha-2A adrenergic receptor		 5								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324737	104022535		CHEMBL92860				ZINC22445308	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127623	C(\C=C\c1ccccc1)N1CCN(C[C@@H]2ON=C3[C@H]2C=Cc2ccccc32)CC1	InChI=1S/C25H27N3O/c1-2-7-20(8-3-1)9-6-14-27-15-17-28(18-16-27)19-24-23-13-12-21-10-4-5-11-22(21)25(23)26-29-24/h1-13,23-24H,14-19H2/b9-6+/t23-,24-/m0/s1	PKXHLBVPUHXZNH-CWPZKOGPSA-N	50024306	CHEMBL2112979	Alpha-2A adrenergic receptor		 43								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024306&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456239	277286506		CHEMBL2112979					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127625	COc1cc2NC[C@H]3[C@H](CN4CCN(Cc5ccc6ncccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C27H31N5O3/c1-33-24-13-20-23(14-25(24)34-2)29-15-21-26(35-30-27(20)21)17-32-10-8-31(9-11-32)16-18-5-6-22-19(12-18)4-3-7-28-22/h3-7,12-14,21,26,29H,8-11,15-17H2,1-2H3/t21-,26-/m0/s1	DDSYDFFJQMGTMM-LVXARBLLSA-N	50024307	CHEMBL2112980	Alpha-2A adrenergic receptor		>1000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024307&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71454489	277286507		CHEMBL2112980					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127630	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2A adrenergic receptor		 0.300000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127637	CN1C[C@H]2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C25H30N4O/c1-27-18-22-24(30-26-25(22)21-11-5-6-12-23(21)27)19-29-16-14-28(15-17-29)13-7-10-20-8-3-2-4-9-20/h2-12,22,24H,13-19H2,1H3/b10-7+/t22-,24-/m0/s1	GHPKBFZQNLPFFZ-PTQQVUJNSA-N	50024312	CHEMBL2112970	Alpha-2A adrenergic receptor		 1.6								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024312&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11200476	277286512		CHEMBL2112970					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127645	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2A adrenergic receptor		 0.800000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127733	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2A adrenergic receptor		 0.300000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50127766	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2A adrenergic receptor		 1.4								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50133591	C[C@@H](N)Cn1ncc2ccc(O)cc12	InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m1/s1	WBYHTZYHAFNBKW-SSDOTTSWSA-N	50180256	1-((R)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL437314	Alpha-2A adrenergic receptor					 1990					ChEMBL	10.1021/jm050663x	10.7270/Q23B5ZQW	16392816			May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180256&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11500503	104065373		CHEMBL437314				ZINC13679044	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50133607	C[C@H](N)Cn1ncc2ccc(O)cc12	InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	WBYHTZYHAFNBKW-ZETCQYMHSA-N	50180251	1-((S)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL371300	Alpha-2A adrenergic receptor					 2600					ChEMBL	10.1021/jm050663x	10.7270/Q23B5ZQW	16392816			May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180251&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9834183	104065368		CHEMBL371300				ZINC00009096	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50133610	C[C@H](N)Cn1ncc2ccc(O)cc12	InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	WBYHTZYHAFNBKW-ZETCQYMHSA-N	50180251	1-((S)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL371300	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1021/jm050663x	10.7270/Q23B5ZQW	16392816			May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180251&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9834183	104065368		CHEMBL371300				ZINC00009096	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50136219	OC1(CCN(CCCC(=O)c2ccc(F)cc2)C1)c1ccc(Cl)cc1	InChI=1S/C20H21ClFNO2/c21-17-7-5-16(6-8-17)20(25)11-13-23(14-20)12-1-2-19(24)15-3-9-18(22)10-4-15/h3-10,25H,1-2,11-14H2	BETHXCLHMRGYBW-UHFFFAOYSA-N	50185474	(+)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::(-)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(-)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-pyrrolidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::CHEMBL150161	Alpha-2A adrenergic receptor		 2239								ChEMBL	10.1016/j.bmcl.2006.03.057	10.7270/Q2571BM5	16621538			Ablordeppey, SY; Lyles-Eggleston, M; Bricker, B; Zhang, W; Zhu, X; Goodman, C; Roth, BL	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185474&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9906978	104069685		CHEMBL150161				ZINC12356157	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50139598	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(Cl)ccc23)cc1	InChI=1S/C23H27ClN4/c1-15-14-28(12-11-27(15)4)20-8-6-19(7-9-20)26-23-16(2)17(3)25-22-13-18(24)5-10-21(22)23/h5-10,13,15H,11-12,14H2,1-4H3,(H,25,26)	QRWKSCTWTCHDII-UHFFFAOYSA-N	50418050	CHEMBL1689423	Alpha-2A adrenergic receptor		 1430								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50418050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50418050&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10318507	163367074		CHEMBL1689423				ZINC66102877	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50152481	Cc1sc(C)c2c1CCC=C2c1cnc[nH]1	InChI=1S/C13H14N2S/c1-8-10-4-3-5-11(12-6-14-7-15-12)13(10)9(2)16-8/h5-7H,3-4H2,1-2H3,(H,14,15)	RLKWQKZPCMICPS-UHFFFAOYSA-N	50085677	4-(1,3-Dimethyl-6,7-dihydro-benzo[c]thiophen-4-yl)-1H-imidazole::CHEMBL284795	Alpha-2A adrenergic receptor		 25								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085677&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220232	103985087		CHEMBL284795				ZINC00024132	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50152486	Cc1sc(C)c2C(CCCc12)c1cnc[nH]1	InChI=1S/C13H16N2S/c1-8-10-4-3-5-11(12-6-14-7-15-12)13(10)9(2)16-8/h6-7,11H,3-5H2,1-2H3,(H,14,15)	AOQYWVCOSJELMS-UHFFFAOYSA-N	50085676	4-(1,3-Dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-4-yl)-1H-imidazole::CHEMBL30739	Alpha-2A adrenergic receptor		 68								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085676&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816063	103985086		CHEMBL30739				ZINC03923487	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50152490	C1CC(c2cnc[nH]2)c2ccsc2C1	InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	BFSPTAYUYXLBEU-UHFFFAOYSA-N	50085678	4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-imidazole::CHEMBL284213	Alpha-2A adrenergic receptor		 27								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085678&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9815633	103985088		CHEMBL284213				ZINC03923482	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50152491	C1Cc2sccc2C(=C1)c1cnc[nH]1	InChI=1S/C11H10N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h2,4-7H,1,3H2,(H,12,13)	BAADWHDQAKDYLX-UHFFFAOYSA-N	50085680	4-(6,7-Dihydro-benzo[b]thiophen-4-yl)-1H-imidazole::CHEMBL286246	Alpha-2A adrenergic receptor		 254								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085680&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9815610	103985090		CHEMBL286246				ZINC04805849	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50152504	C1Cc2ccsc2C(=C1)c1cnc[nH]1	InChI=1S/C11H10N2S/c1-2-8-4-5-14-11(8)9(3-1)10-6-12-7-13-10/h3-7H,1-2H2,(H,12,13)	VXOQWXOKZCWYOS-UHFFFAOYSA-N	50085682	4-(4,5-Dihydro-benzo[b]thiophen-7-yl)-1H-imidazole::CHEMBL30955	Alpha-2A adrenergic receptor		 224								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085682&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9837106	103985092		CHEMBL30955				ZINC00024135	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50152506	c1cc2c(cccc2s1)-c1c[nH]cn1	InChI=1S/C11H8N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h1-7H,(H,12,13)	QRRRICPYXPJYEH-UHFFFAOYSA-N	50085681	4-Benzo[b]thiophen-4-yl-1H-imidazole::CHEMBL30534	Alpha-2A adrenergic receptor		 277								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085681&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10176567	103985091		CHEMBL30534				ZINC00024131	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50152512	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 853								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149426	C(CN1CCCN(CC2COc3ccccc3O2)CC1)OCc1cccnc1Oc1ccccc1	InChI=1S/C28H33N3O4/c1-2-9-24(10-3-1)35-28-23(8-6-13-29-28)21-32-19-18-30-14-7-15-31(17-16-30)20-25-22-33-26-11-4-5-12-27(26)34-25/h1-6,8-13,25H,7,14-22H2	AFRRMVBYOMNLHN-UHFFFAOYSA-N	50263724	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-((2-phenoxypyridin-3-yl)methoxy)ethyl)-1,4-diazepane::CHEMBL491419	Alpha-2A adrenergic receptor		 275								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263724&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579271	104111963		CHEMBL491419				ZINC45498778	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149429	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1cccc(c1)C#N	InChI=1S/C29H31N5O4/c30-19-22-6-3-7-23(18-22)38-29-25(8-4-11-32-29)28(35)31-12-15-33-13-5-14-34(17-16-33)20-24-21-36-26-9-1-2-10-27(26)37-24/h1-4,6-11,18,24H,5,12-17,20-21H2,(H,31,35)	YGAFMXXNJBOVBA-UHFFFAOYSA-N	50263621	2-(3-cyanophenoxy)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL515331	Alpha-2A adrenergic receptor		 208								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263621&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579187	104111894		CHEMBL515331				ZINC40918054	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149443	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)	RNPCOHCWKNMBRI-UHFFFAOYSA-N	50263619	CHEMBL477816::N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)-2-phenoxynicotinamide	Alpha-2A adrenergic receptor		 220								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263619&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579185	104111892		CHEMBL477816				ZINC40421976	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149448	CCCCOc1cccc(n1)C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H36N4O4/c1-2-3-18-32-25-11-6-8-22(28-25)26(31)27-12-15-29-13-7-14-30(17-16-29)19-21-20-33-23-9-4-5-10-24(23)34-21/h4-6,8-11,21H,2-3,7,12-20H2,1H3,(H,27,31)	RVIXAJHMKWFIKC-UHFFFAOYSA-N	50263673	6-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)picolinamide::CHEMBL476569	Alpha-2A adrenergic receptor		 118								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263673&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579230	104111926		CHEMBL476569				ZINC40917448	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149450	COc1ccccc1N1CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C20H24N2O3/c1-23-18-7-3-2-6-17(18)22-12-10-21(11-13-22)14-16-15-24-19-8-4-5-9-20(19)25-16/h2-9,16H,10-15H2,1H3	IQDINXFLUAYBCC-UHFFFAOYSA-N	50263618	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-methoxyphenyl)piperazine::CHEMBL518592	Alpha-2A adrenergic receptor		 506								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263618&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579184	104111891		CHEMBL518592				ZINC20775759	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149452	C(C1CCc2ccccc2O1)N1CCN(Cc2ccccc2)CC1	InChI=1S/C21H26N2O/c1-2-6-18(7-3-1)16-22-12-14-23(15-13-22)17-20-11-10-19-8-4-5-9-21(19)24-20/h1-9,20H,10-17H2	AJZBPCAHQHCXMX-UHFFFAOYSA-N	50159018	1-Benzyl-4-chroman-2-ylmethyl-piperazine::1-benzyl-4-((3,4-dihydro-2H-chromen-2-yl)methyl)piperazine::CHEMBL179648	Alpha-2A adrenergic receptor		 167								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159018&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10758200	104045618		CHEMBL179648				ZINC22445891	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149454	CCCCOc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H36N4O4/c1-2-3-18-32-26-22(8-6-11-28-26)25(31)27-12-15-29-13-7-14-30(17-16-29)19-21-20-33-23-9-4-5-10-24(23)34-21/h4-6,8-11,21H,2-3,7,12-20H2,1H3,(H,27,31)	OYOGQACTFBHTOD-UHFFFAOYSA-N	50263672	2-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL514837	Alpha-2A adrenergic receptor		 81								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263672&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579229	104111925		CHEMBL514837				ZINC40408846	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149457	O=C(NCCN1CCCN(C[C@H]2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)/t23-/m0/s1	RNPCOHCWKNMBRI-QHCPKHFHSA-N	50263774	(S)-N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide::CHEMBL524153	Alpha-2A adrenergic receptor		 94								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263774&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25110718	104111991		CHEMBL524153				ZINC40951657	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149459	CC(C)(C)Nc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H37N5O3/c1-26(2,3)29-24-21(8-6-11-27-24)25(32)28-12-15-30-13-7-14-31(17-16-30)18-20-19-33-22-9-4-5-10-23(22)34-20/h4-6,8-11,20H,7,12-19H2,1-3H3,(H,27,29)(H,28,32)	IPSCUIDJZTXJJO-UHFFFAOYSA-N	50263671	2-(tert-butylamino)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL477608	Alpha-2A adrenergic receptor		 138								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263671&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579228	104111924		CHEMBL477608				ZINC40916745	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50149424	C(C1COc2ccccc2O1)N1CCCN(Cc2nc(no2)-c2cccnc2Oc2ccccc2)CC1	InChI=1S/C28H29N5O4/c1-2-8-21(9-3-1)36-28-23(10-6-13-29-28)27-30-26(37-31-27)19-33-15-7-14-32(16-17-33)18-22-20-34-24-11-4-5-12-25(24)35-22/h1-6,8-13,22H,7,14-20H2	YWALOGYVALOLTL-UHFFFAOYSA-N	50263725	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-((3-(2-phenoxypyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)-1,4-diazepane::CHEMBL491420	Alpha-2A adrenergic receptor		 15								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263725&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579272	104111964		CHEMBL491420				ZINC40424119	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161235	CN1C(=O)C[C@@H](C(C(=O)NCCCN2CCC(CC2)(C#N)c2ccc(F)cc2F)=C1C)c1ccc(F)c(F)c1	InChI=1S/C29H30F4N4O2/c1-18-27(21(16-26(38)36(18)2)19-4-7-23(31)25(33)14-19)28(39)35-10-3-11-37-12-8-29(17-34,9-13-37)22-6-5-20(30)15-24(22)32/h4-7,14-15,21H,3,8-13,16H2,1-2H3,(H,35,39)/t21-/m1/s1	WIVOLWKUZIBRAF-OAQYLSRUSA-N	50090326	(R)-4-(3,4-Difluoro-phenyl)-1,2-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2,4-difluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL295395	Alpha-2A adrenergic receptor		 3388								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090326&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288769	103988821		CHEMBL295395				ZINC29392774	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161261	CN1C(=O)C[C@@H](C(C(=O)NCCCN2CCC(CC2)(C#N)c2ccc(F)cc2)=C1C)c1ccc(F)c(F)c1	InChI=1S/C29H31F3N4O2/c1-19-27(23(17-26(37)35(19)2)20-4-9-24(31)25(32)16-20)28(38)34-12-3-13-36-14-10-29(18-33,11-15-36)21-5-7-22(30)8-6-21/h4-9,16,23H,3,10-15,17H2,1-2H3,(H,34,38)/t23-/m1/s1	PEDXQUUSXXYPJU-HSZRJFAPSA-N	50090330	(R)-4-(3,4-Difluoro-phenyl)-1,2-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL291166	Alpha-2A adrenergic receptor		 1862								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090330&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44289035	103988825		CHEMBL291166				ZINC29389673	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161278	CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)c1ccc(F)cc1C#N	InChI=1S/C28H29F3N4O2/c1-17-27(23(15-26(36)34-17)19-3-6-24(30)25(31)14-19)28(37)33-9-2-10-35-11-7-18(8-12-35)22-5-4-21(29)13-20(22)16-32/h3-6,13-14,18,23H,2,7-12,15H2,1H3,(H,33,37)(H,34,36)/t23-/m1/s1	RQTZTSPFFYDZKA-HSZRJFAPSA-N	50090339	(R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL43491	Alpha-2A adrenergic receptor		 1288								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090339&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9827677	103988834		CHEMBL43491				ZINC29392541	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161289	CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)(C#N)c1ccc(F)cc1C#N	InChI=1S/C29H28F3N5O2/c1-18-27(22(15-26(38)36-18)19-3-6-24(31)25(32)14-19)28(39)35-9-2-10-37-11-7-29(17-34,8-12-37)23-5-4-21(30)13-20(23)16-33/h3-6,13-14,22H,2,7-12,15H2,1H3,(H,35,39)(H,36,38)/t22-/m1/s1	KAXNWVHHUKHNDK-JOCHJYFZSA-N	50090335	(R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL42335	Alpha-2A adrenergic receptor		 7852.0								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090335&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288847	103988830		CHEMBL42335				ZINC29392999	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161291	CN1C(=O)C[C@@H](C(C(=O)NCCCN2CCC(CC2)(C#N)c2ccc(F)cc2C#N)=C1C)c1ccc(F)c(F)c1	InChI=1S/C30H30F3N5O2/c1-19-28(23(16-27(39)37(19)2)20-4-7-25(32)26(33)15-20)29(40)36-10-3-11-38-12-8-30(18-35,9-13-38)24-6-5-22(31)14-21(24)17-34/h4-7,14-15,23H,3,8-13,16H2,1-2H3,(H,36,40)/t23-/m1/s1	LEVRYVCMBBJQLU-HSZRJFAPSA-N	50090333	(R)-4-(3,4-Difluoro-phenyl)-1,2-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL43594	Alpha-2A adrenergic receptor		 13646								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090333&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288877	103988828		CHEMBL43594				ZINC29393193	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161299	CN1C(=O)C[C@@H](C(C(=O)NCCCN2CCC(CC2)c2ccc(F)cc2C#N)=C1C)c1ccc(F)c(F)c1	InChI=1S/C29H31F3N4O2/c1-18-28(24(16-27(37)35(18)2)20-4-7-25(31)26(32)15-20)29(38)34-10-3-11-36-12-8-19(9-13-36)23-6-5-22(30)14-21(23)17-33/h4-7,14-15,19,24H,3,8-13,16H2,1-2H3,(H,34,38)/t24-/m1/s1	DLMPCEBSXNLTAT-XMMPIXPASA-N	50090328	(R)-4-(3,4-Difluoro-phenyl)-1,2-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL288772	Alpha-2A adrenergic receptor		 4519								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090328&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10436842	103988823		CHEMBL288772				ZINC03975459	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161302	CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)(C#N)c1ccc(F)cc1F	InChI=1S/C28H28F4N4O2/c1-17-26(20(15-25(37)35-17)18-3-6-22(30)24(32)13-18)27(38)34-9-2-10-36-11-7-28(16-33,8-12-36)21-5-4-19(29)14-23(21)31/h3-6,13-14,20H,2,7-12,15H2,1H3,(H,34,38)(H,35,37)/t20-/m1/s1	RLMGUPUESXPDFJ-HXUWFJFHSA-N	50090338	(R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2,4-difluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL295001	Alpha-2A adrenergic receptor		 1972								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090338&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288874	103988833		CHEMBL295001				ZINC29393174	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161307	CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)c1ccc(F)cc1	InChI=1S/C27H30F3N3O2/c1-17-26(22(16-25(34)32-17)20-5-8-23(29)24(30)15-20)27(35)31-11-2-12-33-13-9-19(10-14-33)18-3-6-21(28)7-4-18/h3-8,15,19,22H,2,9-14,16H2,1H3,(H,31,35)(H,32,34)/t22-/m1/s1	FKKPXTRMLVLGJG-JOCHJYFZSA-N	50090332	(R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL43860	Alpha-2A adrenergic receptor		 229								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090332&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288945	103988827		CHEMBL43860				ZINC29391912	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50161839	C[C@@H]1OC(=O)N([C@H]1c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)c1ccc(F)cc1	InChI=1S/C25H28F3N3O3/c1-16-23(19-5-8-21(27)22(28)15-19)31(25(33)34-16)24(32)29-11-2-12-30-13-9-18(10-14-30)17-3-6-20(26)7-4-17/h3-8,15-16,18,23H,2,9-14H2,1H3,(H,29,32)/t16-,23+/m0/s1	DTYAFBJXWWLRMA-QMHKHESXSA-N	50090647	(4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxazolidine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::(4S,5S)-4-(3,4-difluorophenyl)-N-(3-(4-(4-fluorophenyl)piperidin-1-yl)propyl)-5-methyl-2-oxooxazolidine-3-carboxamide::4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxazolidine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL96467::SNAP-7915	Alpha-2A adrenergic receptor		>45								ChEMBL	10.1021/jm000085e	10.7270/Q2PZ582K	10956183			Lagu, B; Tian, D; Jeon, Y; Li, C; Wetzel, JM; Nagarathnam, D; Shen, Q; Forray, C; Chang, RS; Broten, TP; Ransom, RW; Chan, TB; O'Malley, SS; Schorn, TW; Rodrigues, AD; Kassahun, K; Pettibone, DJ; Freidinger, RO; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090647&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9830741	103989116		CHEMBL96467				ZINC03921115	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50157604	CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O	InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1	DRHKJLXJIQTDTD-OAHLLOKOSA-N	50060964	(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide::5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide::5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide::CHEMBL836::TAMSULOSIN	Alpha-2A adrenergic receptor		 63								ChEMBL	10.1021/jm9905918	10.7270/Q2XW4J20	10841797			Kuo, GH; Prouty, C; Murray, WV; Pulito, V; Jolliffe, L; Cheung, P; Varga, S; Evangelisto, M; Wang, J	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060964&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	JGX		129211	103956570	9398	CHEMBL836	DB00706	488	C07124	ZINC01530694	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50208182	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(12-19-4-6-20(28)7-5-19)15-30-8-10-31(11-9-30)16-26-22-17-34-23-14-25(33-3)24(32-2)13-21(23)27(22)29-35-26/h4-7,12-14,22,26H,8-11,15-17H2,1-3H3/b18-12+/t22-,26-/m0/s1	UCNOTTVNPRSTFW-XSFNXXSESA-N	50146518	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL318235::R-226161::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2A adrenergic receptor		 28.0								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146518&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16655023	104035107		CHEMBL318235				ZINC26742166	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50197039	COC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12	InChI=1S/C20H23NO2/c1-22-19-17-9-5-6-10-18(17)20(23-19)11-13-21(14-12-20)15-16-7-3-2-4-8-16/h2-10,19H,11-15H2,1H3	RZZAEVQHACUOGI-UHFFFAOYSA-N	50108659	1'-benzyl-3-methoxy-3H-spiro[2-benzofuran-1,4'-piperidine]::1'-benzyl-3-methoxy-3H-spiro[isobenzofuran-1,4'-piperidine]::1'-benzyl-3-methoxyspiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]::CHEMBL138809	Alpha-2A adrenergic receptor			 6200							ChEMBL	10.1021/jm010992z	10.7270/Q2VT1RDH	11784148			Maier, CA; Wunsch, B	Pharmazeutisches Institut der Universit&#228;t Freiburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108659&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10357986	104003841		CHEMBL138809				ZINC13472062	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50197062	COC1Cc2ccccc2C2(CCN(CCCc3ccccc3)CC2)O1	InChI=1S/C23H29NO2/c1-25-22-18-20-11-5-6-12-21(20)23(26-22)13-16-24(17-14-23)15-7-10-19-8-3-2-4-9-19/h2-6,8-9,11-12,22H,7,10,13-18H2,1H3	IJKYJDDNDXAREJ-UHFFFAOYSA-N	50108654	1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]-1-yl]-3-phenylpropane::CHEMBL138458	Alpha-2A adrenergic receptor			 3100							ChEMBL	10.1021/jm010992z	10.7270/Q2VT1RDH	11784148			Maier, CA; Wunsch, B	Pharmazeutisches Institut der Universit&#228;t Freiburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108654&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10915140	104003836		CHEMBL138458				ZINC13472041	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50197078	COC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1	InChI=1S/C21H25NO2/c1-23-20-15-18-9-5-6-10-19(18)21(24-20)11-13-22(14-12-21)16-17-7-3-2-4-8-17/h2-10,20H,11-16H2,1H3	POOPPNNSPMKABZ-UHFFFAOYSA-N	50108653	1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]::1'-benzyl-3-methoxyspiro[isochroman-1,4'-piperidine]::CHEMBL141209	Alpha-2A adrenergic receptor			 3000							ChEMBL	10.1021/jm010992z	10.7270/Q2VT1RDH	11784148			Maier, CA; Wunsch, B	Pharmazeutisches Institut der Universit&#228;t Freiburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108653&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10019102	104003835		CHEMBL141209				ZINC13472033	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50208212	COc1cc2NCC3C(CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H34N4O3/c1-19(13-20-7-5-4-6-8-20)17-30-9-11-31(12-10-30)18-26-22-16-28-23-15-25(33-3)24(32-2)14-21(23)27(22)29-34-26/h4-8,13-15,22,26,28H,9-12,16-18H2,1-3H3/b19-13+	JODRRUQCPGURFJ-CPNJWEJPSA-N	50209684	CHEMBL390718::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole	Alpha-2A adrenergic receptor		 2.4								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209684&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44424854	104086408		CHEMBL390718				ZINC28654956	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50208232	COc1cc2OCC3C(CN4CCN(C\C=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-12-10-29(11-13-30)9-3-4-18-5-7-19(27)8-6-18/h3-8,14-15,21,25H,9-13,16-17H2,1-2H3/b4-3+	CVKQUGPVDVFRAT-ONEGZZNKSA-N	50209685	CHEMBL226636::cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2A adrenergic receptor		 117								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209685&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44424855	104086409		CHEMBL226636				ZINC28654969	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50223277	CCc1cccc(CC)c1OC(C)C1=NCCN1	InChI=1S/C15H22N2O/c1-4-12-7-6-8-13(5-2)14(12)18-11(3)15-16-9-10-17-15/h6-8,11H,4-5,9-10H2,1-3H3,(H,16,17)	OXGCVSXSSWZTMU-UHFFFAOYSA-N	50419884	CHEMBL157955	Alpha-2A adrenergic receptor		 32								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419884&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371864	163368908		CHEMBL157955				ZINC27705893	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50223279	CC(Oc1c(Cl)cccc1Cl)C1=NCCN1	InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)	KSMAGQUYOIHWFS-UHFFFAOYSA-N	50019646	2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline::2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL17860::lofexidine	Alpha-2A adrenergic receptor					 6.3					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019646&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			30668	103930569	51368	CHEMBL17860	DB04948			ZINC00005626	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50222315	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2A adrenergic receptor		 48								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50222331	C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m1/s1	OGOLMGZJNRNULQ-CYBMUJFWSA-N	50417353	CHEMBL242265	Alpha-2A adrenergic receptor		 186								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417353&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11043720	163366377		CHEMBL242265				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50222333	C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m0/s1	OGOLMGZJNRNULQ-ZDUSSCGKSA-N	50417354	CHEMBL396013	Alpha-2A adrenergic receptor		 91								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417354&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10333157	163366378		CHEMBL396013				ZINC00009140	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50222335	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2A adrenergic receptor		 60								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50222351	CC(Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)	IAIZHDGEGFGNMO-UHFFFAOYSA-N	50417347	CHEMBL385310	Alpha-2A adrenergic receptor		 46								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11371902	163366371		CHEMBL385310				ZINC13585567	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50223393	CC(Oc1ccccc1C(C)=O)C1=NCCN1	InChI=1S/C13H16N2O2/c1-9(16)11-5-3-4-6-12(11)17-10(2)13-14-7-8-15-13/h3-6,10H,7-8H2,1-2H3,(H,14,15)	LHYRGWVECGKEOM-UHFFFAOYSA-N	50419888	CHEMBL1956202	Alpha-2A adrenergic receptor		 1023								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395731	163368912		CHEMBL1956202				ZINC73312444	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50223394	CC(Oc1ccccc1C=O)C1=NCCN1	InChI=1S/C12H14N2O2/c1-9(12-13-6-7-14-12)16-11-5-3-2-4-10(11)8-15/h2-5,8-9H,6-7H2,1H3,(H,13,14)	UQOROHPPKUMVNP-UHFFFAOYSA-N	50419883	CHEMBL1956201	Alpha-2A adrenergic receptor		 1047								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419883&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57402718	163368907		CHEMBL1956201				ZINC73312440	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50223403	CC(Oc1ccccc1S(C)(=O)=O)C1=NCCN1	InChI=1S/C12H16N2O3S/c1-9(12-13-7-8-14-12)17-10-5-3-4-6-11(10)18(2,15)16/h3-6,9H,7-8H2,1-2H3,(H,13,14)	BUVSDNNKXQXCRO-UHFFFAOYSA-N	50419882	CHEMBL1956200	Alpha-2A adrenergic receptor		 3162								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419882&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57400959	163368906		CHEMBL1956200				ZINC73312436	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50223408	CC(Oc1c(C)cccc1C)C1=NCCN1	InChI=1S/C13H18N2O/c1-9-5-4-6-10(2)12(9)16-11(3)13-14-7-8-15-13/h4-6,11H,7-8H2,1-3H3,(H,14,15)	JWAAXMLRAVOKBQ-UHFFFAOYSA-N	50419889	CHEMBL155866	Alpha-2A adrenergic receptor					 19					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419889&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371755	163368913		CHEMBL155866				ZINC27710505	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50223424	C1CN=C(N1)[C@@H]1CO[C@@H](CO1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-17-12(9-16-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12-/m0/s1	MPFNVJVLRBBPHX-RYUDHWBXSA-N	50419925	CHEMBL1956899	Alpha-2A adrenergic receptor		 501								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419925&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57393066	163368949		CHEMBL1956899				ZINC73296457	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50222364	C[C@@H](Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)/t11-/m1/s1	IAIZHDGEGFGNMO-LLVKDONJSA-N	50417348	CHEMBL1276247	Alpha-2A adrenergic receptor					 3162					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417348&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836306	163366372		CHEMBL1276247					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50222366	C[C@H](Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)/t11-/m0/s1	IAIZHDGEGFGNMO-NSHDSACASA-N	50417349	CHEMBL1276248	Alpha-2A adrenergic receptor					 63					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417349&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836305	163366373		CHEMBL1276248					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50221926	CC(Oc1ccccc1C1CCCCC1)C1=NCCN1	InChI=1S/C17H24N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h5-6,9-10,13-14H,2-4,7-8,11-12H2,1H3,(H,18,19)	RIMQFOFQYZBTDB-UHFFFAOYSA-N	50412258	CHEMBL451229	Alpha-2A adrenergic receptor		 74								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412258&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23622576	163361282		CHEMBL451229				ZINC40836200	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50221927	C1CN=C(N1)C(Oc1ccccc1-c1ccccc1)c1ccccc1	InChI=1S/C22H20N2O/c1-3-9-17(10-4-1)19-13-7-8-14-20(19)25-21(22-23-15-16-24-22)18-11-5-2-6-12-18/h1-14,21H,15-16H2,(H,23,24)	XXOSLSPHUHLICG-UHFFFAOYSA-N	50412257	CHEMBL523048	Alpha-2A adrenergic receptor		 240								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412257&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906200	163361281		CHEMBL523048				ZINC40957110	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50221940	CC(Oc1ccccc1C1CCCC1)C1=NCCN1	InChI=1S/C16H22N2O/c1-12(16-17-10-11-18-16)19-15-9-5-4-8-14(15)13-6-2-3-7-13/h4-5,8-9,12-13H,2-3,6-7,10-11H2,1H3,(H,17,18)	WIQCERUTOBWUOL-UHFFFAOYSA-N	50412244	CHEMBL495096	Alpha-2A adrenergic receptor					 63					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412244&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906199	163361268		CHEMBL495096				ZINC40430700	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50221953	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2A adrenergic receptor		 48								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50221959	CC(Oc1ccccc1CN=O)C1=NCCN1	InChI=1S/C12H15N3O2/c1-9(12-13-6-7-14-12)17-11-5-3-2-4-10(11)8-15-16/h2-5,9H,6-8H2,1H3,(H,13,14)	FZLNIHYBYXMHEO-UHFFFAOYSA-N	50412249	CHEMBL493675	Alpha-2A adrenergic receptor					 501					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412249&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91900410	163361273		CHEMBL493675				ZINC40430963	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50214202	O=C(Cc1ccccc1)NC1CCN(CCCN2C(=O)COc3ccccc23)CC1	InChI=1S/C24H29N3O3/c28-23(17-19-7-2-1-3-8-19)25-20-11-15-26(16-12-20)13-6-14-27-21-9-4-5-10-22(21)30-18-24(27)29/h1-5,7-10,20H,6,11-18H2,(H,25,28)	FLGSUSWMWSZVMP-UHFFFAOYSA-N	50326218	CHEMBL1242923::N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]-piperidin-4-yl}-2-phenylacetamide	Alpha-2A adrenergic receptor		<1000								ChEMBL	10.1021/jm100697g	10.7270/Q2765G9K	20684563			Sams, AG; Hentzer, M; Mikkelsen, GK; Larsen, K; Bundgaard, C; Plath, N; Christoffersen, CT; Bang-Andersen, B	H. Lundbeck A/S	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326218&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44207909	123105333		CHEMBL1242923		5435		ZINC64573958	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50216434	CN1CCN=C1Cc1cccnc1	InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3	YXPIBYSOCFGTHG-UHFFFAOYSA-N	50094968	3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-pyridine::CHEMBL313631	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm020188s	10.7270/Q2ZW1K88	12361399			Ferretti, G; Dukat, M; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Damaj, MI; Martin, BR; Glennon, RA	Universita di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094968&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10035109	103992788		CHEMBL313631				ZINC13487902	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50238065	CCCCCCCCCCCCCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O	InChI=1S/C88H137N17O18/c1-12-13-14-15-16-17-18-19-20-21-22-23-24-33-71(111)101-72(52(6)7)83(119)104-75(56(11)108)86(122)100-69(45-51(4)5)87(123)105-43-28-32-70(105)82(118)97-65(44-50(2)3)79(115)96-68(48-59-49-93-63-30-26-25-29-62(59)63)78(114)94-53(8)77(113)102-73(54(9)106)84(120)99-67(47-58-36-40-61(110)41-37-58)81(117)103-74(55(10)107)85(121)98-66(46-57-34-38-60(109)39-35-57)80(116)95-64(76(89)112)31-27-42-92-88(90)91/h25-26,29-30,34-41,49-56,64-70,72-75,93,106-110H,12-24,27-28,31-33,42-48H2,1-11H3,(H2,89,112)(H,94,114)(H,95,116)(H,96,115)(H,97,118)(H,98,121)(H,99,120)(H,100,122)(H,101,111)(H,102,113)(H,103,117)(H,104,119)(H4,90,91,92)/t53-,54+,55+,56+,64-,65-,66-,67-,68-,69-,70-,72-,73-,74-,75-/m0/s1	DYIMTVFKTDCCMM-XNNVEVGKSA-N	50027852	CHEMBL3338677	Alpha-2A adrenergic receptor					>30000					ChEMBL	10.1016/j.bmcl.2014.08.045	10.7270/Q2D50PH2	25241924			McKeown, SC; Zecri, FJ; Fortier, E; Taggart, A; Sviridenko, L; Adams, CM; McAllister, KH; Pin, SS	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027852&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118715454	103937282		CHEMBL3338677				ZINC14592974	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239094	COc1cc2OCC3C(CN4CCN(Cc5cc6ccccc6s5)CC4)ON=C3c2cc1OC	InChI=1S/C26H29N3O4S/c1-30-22-12-19-21(13-23(22)31-2)32-16-20-24(33-27-26(19)20)15-29-9-7-28(8-10-29)14-18-11-17-5-3-4-6-25(17)34-18/h3-6,11-13,20,24H,7-10,14-16H2,1-2H3	IHCKEJIXIYLTFT-UHFFFAOYSA-N	50131368	3-(4-Benzo[b]thiophen-2-ylmethyl-piperazin-1-ylmethyl)-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL94435	Alpha-2A adrenergic receptor		 98								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131368	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131368&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324860	104022552		CHEMBL94435				ZINC26655867	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239095	COc1cc2OCC3C(CN4CCN(Cc5ccc6ncccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C27H30N4O4/c1-32-24-13-20-23(14-25(24)33-2)34-17-21-26(35-29-27(20)21)16-31-10-8-30(9-11-31)15-18-5-6-22-19(12-18)4-3-7-28-22/h3-7,12-14,21,26H,8-11,15-17H2,1-2H3	APNJYYQXBHETAR-UHFFFAOYSA-N	50131367	7,8-Dimethoxy-3-(4-quinolin-6-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90966	Alpha-2A adrenergic receptor		 117								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131367&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325038	104022551		CHEMBL90966				ZINC26646277	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239096	COc1cc2OCC3C(CN4CCN(Cc5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C24H29N3O4/c1-28-21-12-18-20(13-22(21)29-2)30-16-19-23(31-25-24(18)19)15-27-10-8-26(9-11-27)14-17-6-4-3-5-7-17/h3-7,12-13,19,23H,8-11,14-16H2,1-2H3	VUTLJDGDPMZCOA-UHFFFAOYSA-N	50131363	3-(4-Benzyl-piperazin-1-ylmethyl)-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90843	Alpha-2A adrenergic receptor		 186								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131363&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324900	104022547		CHEMBL90843				ZINC26645413	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239102	COc1ccc2OCC3C(CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2c1	InChI=1S/C25H29N3O3/c1-29-20-9-10-23-21(16-20)25-22(18-30-23)24(31-26-25)17-28-14-12-27(13-15-28)11-5-8-19-6-3-2-4-7-19/h2-10,16,22,24H,11-15,17-18H2,1H3/b8-5+	FJABWASNVHOPLU-VMPITWQZSA-N	50131350	8-Methoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL422597	Alpha-2A adrenergic receptor		 0.800000								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131350&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324887	104022534		CHEMBL422597				ZINC26646476	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239103	COc1cc2OCC3C(CN4CCN(CCc5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4/c1-29-22-14-19-21(15-23(22)30-2)31-17-20-24(32-26-25(19)20)16-28-12-10-27(11-13-28)9-8-18-6-4-3-5-7-18/h3-7,14-15,20,24H,8-13,16-17H2,1-2H3	AVVCHEPXGGYIRM-UHFFFAOYSA-N	50131362	7,8-Dimethoxy-3-(4-phenethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92496	Alpha-2A adrenergic receptor		 234								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131362&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325079	104022546		CHEMBL92496				ZINC26646298	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50238074	CCCCCCCCCCCCCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O	InChI=1S/C88H137N17O18/c1-12-13-14-15-16-17-18-19-20-21-22-23-24-33-71(111)101-72(52(6)7)83(119)104-75(56(11)108)86(122)100-69(45-51(4)5)87(123)105-43-28-32-70(105)82(118)97-65(44-50(2)3)79(115)96-68(48-59-49-93-63-30-26-25-29-62(59)63)78(114)94-53(8)77(113)102-73(54(9)106)84(120)99-67(47-58-36-40-61(110)41-37-58)81(117)103-74(55(10)107)85(121)98-66(46-57-34-38-60(109)39-35-57)80(116)95-64(76(89)112)31-27-42-92-88(90)91/h25-26,29-30,34-41,49-56,64-70,72-75,93,106-110H,12-24,27-28,31-33,42-48H2,1-11H3,(H2,89,112)(H,94,114)(H,95,116)(H,96,115)(H,97,118)(H,98,121)(H,99,120)(H,100,122)(H,101,111)(H,102,113)(H,103,117)(H,104,119)(H4,90,91,92)/t53-,54+,55+,56+,64-,65-,66-,67-,68-,69-,70-,72-,73-,74-,75-/m0/s1	DYIMTVFKTDCCMM-XNNVEVGKSA-N	50027852	CHEMBL3338677	Alpha-2A adrenergic receptor			>30000							ChEMBL	10.1016/j.bmcl.2014.08.045	10.7270/Q2D50PH2	25241924			McKeown, SC; Zecri, FJ; Fortier, E; Taggart, A; Sviridenko, L; Adams, CM; McAllister, KH; Pin, SS	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027852&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118715454	103937282		CHEMBL3338677				ZINC14592974	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239000	COc1cc2OCC3C(CN4CCN(Cc5csc6ccccc56)CC4)ON=C3c2cc1OC	InChI=1S/C26H29N3O4S/c1-30-22-11-19-21(12-23(22)31-2)32-15-20-24(33-27-26(19)20)14-29-9-7-28(8-10-29)13-17-16-34-25-6-4-3-5-18(17)25/h3-6,11-12,16,20,24H,7-10,13-15H2,1-2H3	SNKCREOVGWDJDI-UHFFFAOYSA-N	50131352	3-(4-Benzo[b]thiophen-3-ylmethyl-piperazin-1-ylmethyl)-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL93801	Alpha-2A adrenergic receptor		 66								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131352&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325044	104022536		CHEMBL93801				ZINC26657477	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239006	COc1cc2OCC3C(CN4CCN(CC5=Cc6ccccc6C5)CC4)ON=C3c2cc1OC	InChI=1S/C27H31N3O4/c1-31-24-13-21-23(14-25(24)32-2)33-17-22-26(34-28-27(21)22)16-30-9-7-29(8-10-30)15-18-11-19-5-3-4-6-20(19)12-18/h3-6,11,13-14,22,26H,7-10,12,15-17H2,1-2H3	AQDOXXILINNVJB-UHFFFAOYSA-N	50131356	3-[4-(1H-Inden-2-ylmethyl)-piperazin-1-ylmethyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328377	Alpha-2A adrenergic receptor		 22								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131356&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324859	104022540		CHEMBL328377				ZINC26655851	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239008	COc1cc2OCC3C(CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+	JWYUBODPEUBFLH-CPNJWEJPSA-N	50131353	7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL93171	Alpha-2A adrenergic receptor		 0.800000								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131353&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325050	104022537		CHEMBL93171				ZINC22930658	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239012	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C/c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6-/t21-,25-/m0/s1	WZOMJNATDSYQHS-VTYJTISCSA-N	50131349	(R)-7,8-Dimethoxy-3-[4-((Z)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL420830	Alpha-2A adrenergic receptor		 35.0								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131349&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330571	104022533		CHEMBL420830				ZINC26654774	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239021	COc1cc2OCC3C(CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3	XHLHZPFSBCZVEA-UHFFFAOYSA-N	50131354	7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL94129	Alpha-2A adrenergic receptor		 5								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131354&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44215744	104022538		CHEMBL94129				ZINC22930675	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239022	COc1cc2OCC3C(CN4CCN(Cc5cnc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C27H30N4O4/c1-32-24-12-20-23(13-25(24)33-2)34-17-21-26(35-29-27(20)21)16-31-9-7-30(8-10-31)15-18-11-19-5-3-4-6-22(19)28-14-18/h3-6,11-14,21,26H,7-10,15-17H2,1-2H3	SWMRFMZFBGUQMK-UHFFFAOYSA-N	50131361	7,8-Dimethoxy-3-(4-quinolin-3-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91824	Alpha-2A adrenergic receptor		 34								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131361&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325027	104022545		CHEMBL91824				ZINC26644023	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50236901	CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(NCCc3ccc(CCC(=O)Nc4ccc(OC(C)=O)c(c4)[N+]([O-])=O)cc3)nc12	InChI=1S/C31H35N9O9/c1-3-33-29(45)26-24(43)25(44)30(49-26)39-15-35-23-27(32)37-31(38-28(23)39)34-13-12-18-6-4-17(5-7-18)8-11-22(42)36-19-9-10-21(48-16(2)41)20(14-19)40(46)47/h4-7,9-10,14-15,24-26,30,43-44H,3,8,11-13H2,1-2H3,(H,33,45)(H,36,42)(H3,32,34,37,38)/t24-,25+,26-,30+/m0/s1	FDVZSKDDSYLYNX-YRIIQKNPSA-N	50026816	CHEMBL3335523	Alpha-2A adrenergic receptor				 1.0						ChEMBL	10.1021/ml5002486	10.7270/Q2VD712G	25221664			Moss, SM; Jayasekara, PS; Paoletta, S; Gao, ZG; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026816&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118714540	103936400		CHEMBL3335523				ZINC28227903	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239037	COc1ccc2C3=NOC(CN4CCN(C\C=C\c5ccccc5)CC4)C3COc2c1	InChI=1S/C25H29N3O3/c1-29-20-9-10-21-23(16-20)30-18-22-24(31-26-25(21)22)17-28-14-12-27(13-15-28)11-5-8-19-6-3-2-4-7-19/h2-10,16,22,24H,11-15,17-18H2,1H3/b8-5+	WDCPMDKQCCZVEW-VMPITWQZSA-N	50131348	7-Methoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90247	Alpha-2A adrenergic receptor		 0.500000								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131348&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324906	104022532		CHEMBL90247				ZINC26651989	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239042	COc1cc2OCC3C(CN4CCN(Cc5cccc6ccccc56)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-12-10-30(11-13-31)16-20-8-5-7-19-6-3-4-9-21(19)20/h3-9,14-15,23,27H,10-13,16-18H2,1-2H3	JNMSRIDVZNTYJE-UHFFFAOYSA-N	50131364	7,8-Dimethoxy-3-(4-naphthalen-1-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91297	Alpha-2A adrenergic receptor		 234								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131364&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325028	104022548		CHEMBL91297				ZINC26644039	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239043	COc1cc2OCC3C(CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+	YMYZKGIHGMHZDL-DJKKODMXSA-N	50131365	7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL327875	Alpha-2A adrenergic receptor		 1.4								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131365&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325049	104022549		CHEMBL327875				ZINC22930667	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239049	COc1cc2OCC3C(CN4CCN(CCCc5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H33N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-5,7-8,15-16,21,25H,6,9-14,17-18H2,1-2H3	WYFPZXUWZCKNMJ-UHFFFAOYSA-N	50131366	7,8-Dimethoxy-3-[4-(3-phenyl-propyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90419	Alpha-2A adrenergic receptor		 26								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131366&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324725	104022550		CHEMBL90419				ZINC26646012	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239072	Fc1ccc2CC(CC3CNC=N3)Cc2c1	InChI=1S/C13H15FN2/c14-12-2-1-10-3-9(4-11(10)6-12)5-13-7-15-8-16-13/h1-2,6,8-9,13H,3-5,7H2,(H,15,16)	HBMJQYDGBNSZMC-UHFFFAOYSA-N	50131357	4-(5-Fluoro-indan-2-ylmethyl)-4,5-dihydro-1H-imidazole::CHEMBL90997::S-34324	Alpha-2A adrenergic receptor		 5.9								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131357&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220053	104022541		CHEMBL90997				ZINC26652869	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239073	C(\C=C\c1ccccc1)N1CCN(CC2ON=C3C2COc2ccccc32)CC1	InChI=1S/C24H27N3O2/c1-2-7-19(8-3-1)9-6-12-26-13-15-27(16-14-26)17-23-21-18-28-22-11-5-4-10-20(22)24(21)25-29-23/h1-11,21,23H,12-18H2/b9-6+	MUUSOYWTPTTZII-RMKNXTFCSA-N	50131360	3-[4-((E)-3-Phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90943	Alpha-2A adrenergic receptor		 0.900000								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131360&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324937	104022544		CHEMBL90943				ZINC26648694	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239084	COc1cc2OCC3C(CN4CCN(CCC(=O)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O5/c1-31-23-14-19-22(15-24(23)32-2)33-17-20-25(34-27-26(19)20)16-29-12-10-28(11-13-29)9-8-21(30)18-6-4-3-5-7-18/h3-7,14-15,20,25H,8-13,16-17H2,1-2H3	AWPNMWRTPSQMFC-UHFFFAOYSA-N	50131358	3-[4-(7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-3-ylmethyl)-piperazin-1-yl]-1-phenyl-propan-1-one::CHEMBL328735	Alpha-2A adrenergic receptor		 12								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131358&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325075	104022542		CHEMBL328735				ZINC26644321	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239085	COc1cc2OCC3C(CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+	WZOMJNATDSYQHS-RMKNXTFCSA-N	50131355	7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL93489	Alpha-2A adrenergic receptor		 8.8								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131355&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9846548	104022539		CHEMBL93489				ZINC22930650	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50239088	COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12	InChI=1S/C23H27NO2/c1-24(13-11-17-9-10-18-12-14-26-23(18)15-17)16-19-5-3-7-21-20(19)6-4-8-22(21)25-2/h4,6,8-10,12,14-15,19H,3,5,7,11,13,16H2,1-2H3/t19-/m0/s1	MHPMXTGKTXJIDI-IBGZPJMESA-N	50057128	(2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amine::A-80426::CHEMBL268258	Alpha-2A adrenergic receptor		 2.4								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057128&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9928332	103953208		CHEMBL268258				ZINC03810797	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50250020	COc1ccc2c3CCNCc3[nH]c2c1	InChI=1S/C12H14N2O/c1-15-8-2-3-9-10-4-5-13-7-12(10)14-11(9)6-8/h2-3,6,13-14H,4-5,7H2,1H3	SCIRNASYBOGBOO-UHFFFAOYSA-N	50132097	7-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL6310	Alpha-2A adrenergic receptor		 1370								ChEMBL	10.1016/j.bmcl.2003.09.027	10.7270/Q2D21X2G	14643338			Grella, B; Teitler, M; Smith, C; Herrick-Davis, K; Glennon, RA	Virginia Commonwealth University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132097&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			599482	104023122		CHEMBL6310				ZINC13587968	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50250041	COc1ccc2c(c1)[nH]c1c(C)nccc21	InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	BXNJHAXVSOCGBA-UHFFFAOYSA-N	100152	7-methoxy-1-methyl-9H-beta-carboline;hydrochloride::7-methoxy-1-methyl-9H-pyrido[3,4-b]indole;hydrochloride::HARMINE::Harmine hydrochloride::MLS002153910::SMR001233259::cid_5359389	Alpha-2A adrenergic receptor		 2540								ChEMBL	10.1016/j.bmcl.2003.09.027	10.7270/Q2D21X2G	14643338			Grella, B; Teitler, M; Smith, C; Herrick-Davis, K; Glennon, RA	Virginia Commonwealth University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=100152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=100152&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HRM	7X9D,5Y86,2Z5X,3ANR,2Z5Y	5280953	252663240	28121		DB07919		C06538	ZINC18847046	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50266445	CN1CCc2c(C1)c1cccc3-c4ccccc4CCn2c13	InChI=1S/C20H20N2/c1-21-11-10-19-18(13-21)17-8-4-7-16-15-6-3-2-5-14(15)9-12-22(19)20(16)17/h2-8H,9-13H2,1H3	XKGPHJMKJBEURD-UHFFFAOYSA-N	50445614	CHEMBL3104093	Alpha-2A adrenergic receptor		 407								ChEMBL	10.1016/j.bmcl.2014.05.016	10.7270/Q28K7BQ5	24863744			Rajagopalan, P; Tracey, H; Chen, Z; Bandyopadhyaya, A; Veeraraghavan, S; Rajagopalan, DR; Salvemini, D; McPhee, I; Viswanadha, S; Rajagopalan, R	University of Missouri	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50445614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50445614&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			73213196	194943510		CHEMBL3104093					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268942	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2A adrenergic receptor		 0.800000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268945	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C/c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6-/t21-,25-/m0/s1	WZOMJNATDSYQHS-VTYJTISCSA-N	50146499	(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL420830	Alpha-2A adrenergic receptor		 23								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146499&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330571	104035088		CHEMBL420830				ZINC22930607	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268946	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2A adrenergic receptor		 8.8								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268953	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccc(F)cc5F)CC4)ON=C3c2cc1OC	InChI=1S/C27H31F2N3O4/c1-17(19-5-4-18(28)12-22(19)29)6-7-31-8-10-32(11-9-31)15-26-21-16-35-23-14-25(34-3)24(33-2)13-20(23)27(21)30-36-26/h4-6,12-14,21,26H,7-11,15-16H2,1-3H3/b17-6+/t21-,26-/m0/s1	KOMMMRWKUHRBSF-NMDKTAKLSA-N	50146507	(3R,3aS)-3-{4-[3-(2,4-Difluoro-phenyl)-but-2-enyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328631	Alpha-2A adrenergic receptor		 9.3								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146507&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10028898	104035096		CHEMBL328631				ZINC26733925	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268957	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cccs5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4S/c1-17(11-18-5-4-10-33-18)14-27-6-8-28(9-7-27)15-24-20-16-31-21-13-23(30-3)22(29-2)12-19(21)25(20)26-32-24/h4-5,10-13,20,24H,6-9,14-16H2,1-3H3/b17-11+/t20-,24-/m0/s1	JPNJJWFOEQLLSP-FJEUJEQTSA-N	50146498	(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-thiophen-2-yl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL98646	Alpha-2A adrenergic receptor		 1.7								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146498&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330653	104035087		CHEMBL98646				ZINC26740265	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268962	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccsc5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4S/c1-17(10-18-4-9-33-16-18)13-27-5-7-28(8-6-27)14-24-20-15-31-21-12-23(30-3)22(29-2)11-19(21)25(20)26-32-24/h4,9-12,16,20,24H,5-8,13-15H2,1-3H3/b17-10+/t20-,24-/m0/s1	IPLOTOHAAAUTMK-UDUWVDIRSA-N	50146510	(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-thiophen-3-yl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL101596	Alpha-2A adrenergic receptor		 1.1								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146510&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330668	104035099		CHEMBL101596				ZINC26743248	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268973	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(19-4-6-20(28)7-5-19)8-9-30-10-12-31(13-11-30)16-26-22-17-34-23-15-25(33-3)24(32-2)14-21(23)27(22)29-35-26/h4-8,14-15,22,26H,9-13,16-17H2,1-3H3/b18-8+/t22-,26-/m0/s1	BLAVUEWHVKGIIM-FHYDSMICSA-N	50146512	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-but-2-enyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL98541	Alpha-2A adrenergic receptor		 2.9								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146512&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10480357	104035101		CHEMBL98541				ZINC26741071	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268974	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5OC)CC4)ON=C3c2cc1OC	InChI=1S/C28H35N3O5/c1-19(20-7-5-6-8-23(20)32-2)9-10-30-11-13-31(14-12-30)17-27-22-18-35-24-16-26(34-4)25(33-3)15-21(24)28(22)29-36-27/h5-9,15-16,22,27H,10-14,17-18H2,1-4H3/b19-9+/t22-,27-/m0/s1	NJTFNKZJGXSOMJ-CACUEOBGSA-N	50146514	(3R,3aS)-7,8-Dimethoxy-3-{4-[3-(2-methoxy-phenyl)-but-2-enyl]-piperazin-1-ylmethyl}-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL101361	Alpha-2A adrenergic receptor		 5.2								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146514&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330857	104035103		CHEMBL101361				ZINC26746329	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268978	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccc(O)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O5/c1-18(19-4-6-20(31)7-5-19)8-9-29-10-12-30(13-11-29)16-26-22-17-34-23-15-25(33-3)24(32-2)14-21(23)27(22)28-35-26/h4-8,14-15,22,26,31H,9-13,16-17H2,1-3H3/b18-8+/t22-,26-/m0/s1	VMLJCXYBTLCGDU-FHYDSMICSA-N	50146511	4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-3-ylmethyl)-piperazin-1-yl]-1-methyl-propenyl}-phenol::CHEMBL329065	Alpha-2A adrenergic receptor		 1.9								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146511&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330368	104035100		CHEMBL329065				ZINC26738282	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268981	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccco5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O5/c1-17(11-18-5-4-10-31-18)14-27-6-8-28(9-7-27)15-24-20-16-32-21-13-23(30-3)22(29-2)12-19(21)25(20)26-33-24/h4-5,10-13,20,24H,6-9,14-16H2,1-3H3/b17-11+/t20-,24-/m0/s1	KSQAWHREGPMSBF-FJEUJEQTSA-N	50146504	(3R,3aS)-3-[4-(3-Furan-2-yl-2-methyl-allyl)-piperazin-1-ylmethyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL99916	Alpha-2A adrenergic receptor		 1.7								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146504&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330645	104035093		CHEMBL99916				ZINC26730711	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268983	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5cccs5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4S/c1-17(24-5-4-12-33-24)6-7-27-8-10-28(11-9-27)15-23-19-16-31-20-14-22(30-3)21(29-2)13-18(20)25(19)26-32-23/h4-6,12-14,19,23H,7-11,15-16H2,1-3H3/b17-6+/t19-,23-/m0/s1	JBOWHEDUACRXHK-KJMIXQDXSA-N	50146502	(3R,3aS)-7,8-Dimethoxy-3-[4-(3-thiophen-2-yl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL100879	Alpha-2A adrenergic receptor		 0.300000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146502&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330168	104035091		CHEMBL100879				ZINC26742847	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268984	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cc(F)ccc5F)CC4)ON=C3c2cc1OC	InChI=1S/C27H31F2N3O4/c1-17(10-18-11-19(28)4-5-22(18)29)14-31-6-8-32(9-7-31)15-26-21-16-35-23-13-25(34-3)24(33-2)12-20(23)27(21)30-36-26/h4-5,10-13,21,26H,6-9,14-16H2,1-3H3/b17-10+/t21-,26-/m0/s1	NDIXVNRNAFQAJZ-HNQXZTCOSA-N	50146501	(3R,3aS)-3-{4-[3-(2,5-Difluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL319119	Alpha-2A adrenergic receptor		 0.300000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146501&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11225779	104035090		CHEMBL319119				ZINC22582170	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268985	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cccc(F)c5F)CC4)ON=C3c2cc1OC	InChI=1S/C27H31F2N3O4/c1-17(11-18-5-4-6-21(28)26(18)29)14-31-7-9-32(10-8-31)15-25-20-16-35-22-13-24(34-3)23(33-2)12-19(22)27(20)30-36-25/h4-6,11-13,20,25H,7-10,14-16H2,1-3H3/b17-11+/t20-,25-/m0/s1	HQDWMIAYEGTBSF-DAJVNYJUSA-N	50146517	(3R,3aS)-3-{4-[3-(2,3-Difluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419336	Alpha-2A adrenergic receptor		 3								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146517&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330427	104035106		CHEMBL419336				ZINC26735979	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268987	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5OC)CC4)ON=C3c2cc1OC	InChI=1S/C28H35N3O5/c1-19(13-20-7-5-6-8-23(20)32-2)16-30-9-11-31(12-10-30)17-27-22-18-35-24-15-26(34-4)25(33-3)14-21(24)28(22)29-36-27/h5-8,13-15,22,27H,9-12,16-18H2,1-4H3/b19-13+/t22-,27-/m0/s1	PYXVPLGVUNHGEJ-VKAKAFFBSA-N	50146515	(3R,3aS)-7,8-Dimethoxy-3-{4-[3-(2-methoxy-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL99868	Alpha-2A adrenergic receptor		 1								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330635	104035104		CHEMBL99868				ZINC26735150	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268988	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccsc5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4S/c1-17(18-5-11-33-16-18)4-6-27-7-9-28(10-8-27)14-24-20-15-31-21-13-23(30-3)22(29-2)12-19(21)25(20)26-32-24/h4-5,11-13,16,20,24H,6-10,14-15H2,1-3H3/b17-4+/t20-,24-/m0/s1	BSOFNSGMVOMVLM-MWXPQOEXSA-N	50146513	(3R,3aS)-7,8-Dimethoxy-3-[4-(3-thiophen-3-yl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328195	Alpha-2A adrenergic receptor		 1.4								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146513&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330369	104035102		CHEMBL328195				ZINC26738287	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268991	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5cccc(F)c5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-11-9-29(10-12-30)8-4-6-18-5-3-7-19(27)13-18/h3-7,13-15,21,25H,8-12,16-17H2,1-2H3/b6-4+/t21-,25-/m0/s1	WNCGPEYSCDVJNB-UHRPABQZSA-N	50146503	(3R,3aS)-3-{4-[3-(3-Fluoro-phenyl)-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL95218	Alpha-2A adrenergic receptor		 5.9								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146503&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330598	104035092		CHEMBL95218				ZINC26730263	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268992	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cccnc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H32N4O4/c1-18(11-19-5-4-6-27-14-19)15-29-7-9-30(10-8-29)16-25-21-17-33-22-13-24(32-3)23(31-2)12-20(22)26(21)28-34-25/h4-6,11-14,21,25H,7-10,15-17H2,1-3H3/b18-11+/t21-,25-/m0/s1	GEBHRBBICJPJRU-BFAOIYKGSA-N	50146509	(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-pyridin-3-yl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL98889	Alpha-2A adrenergic receptor		 22								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146509	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146509&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330679	104035098		CHEMBL98889				ZINC26738217	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268993	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-12-10-29(11-13-30)9-3-4-18-5-7-19(27)8-6-18/h3-8,14-15,21,25H,9-13,16-17H2,1-2H3/b4-3+/t21-,25-/m0/s1	CVKQUGPVDVFRAT-SKBIIQSFSA-N	50146500	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419894	Alpha-2A adrenergic receptor		 9								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146500&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330609	104035089		CHEMBL419894				ZINC26741131	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268994	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2A adrenergic receptor		 0.300000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50268996	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccc(Cl)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30ClN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-12-10-29(11-13-30)9-3-4-18-5-7-19(27)8-6-18/h3-8,14-15,21,25H,9-13,16-17H2,1-2H3/b4-3+/t21-,25-/m0/s1	HJACXCAXDLNLEL-SKBIIQSFSA-N	50146508	(3R,3aS)-3-{4-[3-(4-Chloro-phenyl)-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL101411	Alpha-2A adrenergic receptor		 69								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146508&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330621	104035097		CHEMBL101411				ZINC26747193	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50269000	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccco5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O5/c1-17(20-5-4-12-31-20)6-7-27-8-10-28(11-9-27)15-24-19-16-32-21-14-23(30-3)22(29-2)13-18(21)25(19)26-33-24/h4-6,12-14,19,24H,7-11,15-16H2,1-3H3/b17-6+/t19-,24-/m0/s1	SYULCMQGHBLEEJ-GOANZFJNSA-N	50146516	(3R,3aS)-3-[4-(3-Furan-2-yl-but-2-enyl)-piperazin-1-ylmethyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL319530	Alpha-2A adrenergic receptor		 0.500000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146516&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330114	104035105		CHEMBL319530				ZINC26741684	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50269003	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(12-19-4-6-20(28)7-5-19)15-30-8-10-31(11-9-30)16-26-22-17-34-23-14-25(33-3)24(32-2)13-21(23)27(22)29-35-26/h4-7,12-14,22,26H,8-11,15-17H2,1-3H3/b18-12+/t22-,26-/m0/s1	UCNOTTVNPRSTFW-XSFNXXSESA-N	50146518	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL318235::R-226161::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2A adrenergic receptor		 3.4								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146518&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16655023	104035107		CHEMBL318235				ZINC26742166	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50269010	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cccc(F)c5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(11-19-5-4-6-20(28)12-19)15-30-7-9-31(10-8-30)16-26-22-17-34-23-14-25(33-3)24(32-2)13-21(23)27(22)29-35-26/h4-6,11-14,22,26H,7-10,15-17H2,1-3H3/b18-11+/t22-,26-/m0/s1	JCJVFLLBDXJJPW-QJOHKBMMSA-N	50146506	(3R,3aS)-3-{4-[3-(3-Fluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL263424	Alpha-2A adrenergic receptor		 1.1								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146506&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330617	104035095		CHEMBL263424				ZINC26742934	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50269012	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5F)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-19-22(15-24(23)32-2)33-17-20-25(34-28-26(19)20)16-30-12-10-29(11-13-30)9-5-7-18-6-3-4-8-21(18)27/h3-8,14-15,20,25H,9-13,16-17H2,1-2H3/b7-5+/t20-,25-/m0/s1	LEHLBTBBMZYRBK-UABDMCKPSA-N	50146505	(3R,3aS)-3-{4-[3-(2-Fluoro-phenyl)-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL319573	Alpha-2A adrenergic receptor		 2.9								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146505&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330584	104035094		CHEMBL319573				ZINC26735504	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50309010	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15?,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-YGRBPWIASA-N	50167576	(1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester::CHEMBL196400	Alpha-2A adrenergic receptor		 1.4								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167576&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402476	104052792	48565	CHEMBL196400				ZINC06145324	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50309011	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC2[C@H]1C(=O)NCCCC(=O)OCc1ccccc1	InChI=1S/C31H37N3O4/c35-27-13-12-21-18-34-16-14-23-22-9-4-5-10-25(22)33-30(23)26(34)17-24(21)29(27)31(37)32-15-6-11-28(36)38-19-20-7-2-1-3-8-20/h1-5,7-10,21,24,26-27,29,33,35H,6,11-19H2,(H,32,37)/t21-,24?,26-,27-,29+/m0/s1	JZGCFEQRHXUOAB-BUCDTFABSA-N	50167573	4-[((1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carbonyl)-amino]-butyric acid benzyl ester::CHEMBL196451	Alpha-2A adrenergic receptor		 29								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167573&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11203101	104052789		CHEMBL196451				ZINC28525603	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300481	CN(C)C[C@H]1CC2[C@H](O1)c1cc(F)ccc1Sc1ccccc21	InChI=1S/C19H20FNOS/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	BSOLCASXROXPRZ-MQSINFNDSA-N	50162957	(11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL193639	Alpha-2A adrenergic receptor		 66.0								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162957&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401164	104049050		CHEMBL193639				ZINC28523621	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300486	CN1CCN2C(C1)c1ccccc1Cc1cccnc21	InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3	RONZAEMNMFQXRA-UHFFFAOYSA-N	50115644	(+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON	Alpha-2A adrenergic receptor		 20								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115644&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4205	104009532	6950	CHEMBL654	DB00370	7241	C07570	ZINC19702119	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300510	CN(C)C[C@H]1CC2[C@H](O1)c1cc(F)ccc1Sc1ccccc21	InChI=1S/C19H20FNOS/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	BSOLCASXROXPRZ-MQSINFNDSA-N	50162957	(11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL193639	Alpha-2A adrenergic receptor		 66								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162957&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401164	104049050		CHEMBL193639				ZINC28523621	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300513	CN(C)C[C@H]1CC2[C@H](O1)c1cc(F)ccc1Oc1ccccc21	InChI=1S/C19H20FNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	LGHLMADLDHUIJY-MQSINFNDSA-N	50162960	(11-Fluoro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL194659	Alpha-2A adrenergic receptor		 269								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162960	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162960&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401041	104049053		CHEMBL194659				ZINC28523021	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300537	CN(C)C[C@@H]1CC2[C@H](O1)c1cc(F)ccc1Sc1ccccc21	InChI=1S/C19H20FNOS/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19-/m0/s1	BSOLCASXROXPRZ-SHZHJNINSA-N	50162964	(11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL363581	Alpha-2A adrenergic receptor		 72								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162964&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401106	104049057		CHEMBL363581				ZINC28523813	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300562	CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	KVWDHTXUZHCGIO-UHFFFAOYSA-N	35254	2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine	Alpha-2A adrenergic receptor		 192								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4585	85753333	7735	CHEMBL715	DB00334	47	C07322	ZINC52957434	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300568	CN(C)C[C@H]1CC2[C@H](O1)c1cc(Cl)ccc1Oc1ccccc21	InChI=1S/C19H20ClNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	RHPCETHLGGFAQB-MQSINFNDSA-N	50162961	(11-Chloro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL435301	Alpha-2A adrenergic receptor		 10								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162961&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401243	104049054		CHEMBL435301				ZINC28521179	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300570	Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H	YNPFMWCWRVTGKJ-UHFFFAOYSA-N	31005	2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551	Alpha-2A adrenergic receptor		 4.8								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68551	242052839						ZINC00000504	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300592	CN(C)C[C@@H]1CC2[C@H](O1)c1cc(Cl)ccc1Oc1ccccc21	InChI=1S/C19H20ClNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19-/m0/s1	RHPCETHLGGFAQB-SHZHJNINSA-N	50162965	(11-Chloro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL364270	Alpha-2A adrenergic receptor		 302								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162965&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401042	104049058		CHEMBL364270				ZINC13980700	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300598	CN(C)C[C@H]1C[C@H]2[C@H](O1)c1cc(F)ccc1Sc1ccccc21	InChI=1S/C19H20FNOS/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15-,19+/m1/s1	BSOLCASXROXPRZ-MUKKUYKPSA-N	50162959	(11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL366164	Alpha-2A adrenergic receptor		 156								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162959&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11186523	104049052		CHEMBL366164					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300603	CN(C)C[C@H]1CC2[C@H](O1)c1cc(Br)ccc1Oc1ccccc21	InChI=1S/C19H20BrNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	FXHLGRYCQSRFHY-MQSINFNDSA-N	50162958	(11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL193435	Alpha-2A adrenergic receptor		 407								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162958	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162958&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401105	104049051		CHEMBL193435				ZINC28523812	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300610	CN(C)C[C@@H]1CC2[C@H](O1)c1cc(F)ccc1Oc1ccccc21	InChI=1S/C19H20FNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19-/m0/s1	LGHLMADLDHUIJY-SHZHJNINSA-N	50162963	(11-Fluoro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL195706	Alpha-2A adrenergic receptor		 251								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162963	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162963&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401194	104049056		CHEMBL195706				ZINC28523216	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300613	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	QZUDBNBUXVUHMW-UHFFFAOYSA-N	50001884	2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine	Alpha-2A adrenergic receptor		 24								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	103916251	3766	CHEMBL42CHEMBL538973	DB00363	38	C06924	ZINC19796155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300624	CN(C)C[C@H]1CC2[C@H](O1)c1ccccc1Cc1ccccc21	InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19?,20-/m1/s1	ACTVOFFLDWZANE-ZNCRQWOUSA-N	50162956	CHEMBL371352::Dimethyl-(11-methyl-3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-ylmethyl)-amine	Alpha-2A adrenergic receptor		 126								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162956&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401612	104049049		CHEMBL371352				ZINC26670194	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50300628	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone	Alpha-2A adrenergic receptor		 10								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252	8871	CHEMBL85	DB00734	96		ZINC00538312	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295401	CC1Cc2ccc(cc2CN1)[N+]([O-])=O	InChI=1S/C10H12N2O2/c1-7-4-8-2-3-10(12(13)14)5-9(8)6-11-7/h2-3,5,7,11H,4,6H2,1H3	OTVSEAHLIUCIKT-UHFFFAOYSA-N	50077543	3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoline::3-methyl-7-nitro-1,2,3,4-tetrahydroisoquinoline::CHEMBL59719	Alpha-2A adrenergic receptor		 4840								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077543&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			15407445	103970312		CHEMBL59719				ZINC13687084	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295402	[O-][N+](=O)c1ccc2CC(CF)NCc2c1	InChI=1S/C10H11FN2O2/c11-5-9-3-7-1-2-10(13(14)15)4-8(7)6-12-9/h1-2,4,9,12H,3,5-6H2	UVZIROVIMYDLKZ-UHFFFAOYSA-N	50080521	3-Fluoromethyl-7-nitro-1,2,3,4-tetrahydro-isoquinoline::CHEMBL97282	Alpha-2A adrenergic receptor		 3200								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080521&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10584556	103980678		CHEMBL97282				ZINC13686913	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295403	OCC1Cc2ccc(cc2CN1)[N+]([O-])=O	InChI=1S/C10H12N2O3/c13-6-9-3-7-1-2-10(12(14)15)4-8(7)5-11-9/h1-2,4,9,11,13H,3,5-6H2	RNUCRXHRBPLYTA-UHFFFAOYSA-N	50077537	(+)-(7-nitro-1,2,3,4-tetrahydroisoquinolin-3-yl)methanol::(7-Nitro-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol::CHEMBL59441	Alpha-2A adrenergic receptor		 3900								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077537&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HNT	2G70	21584368	103970306		CHEMBL59441				ZINC13797973	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295406	Clc1ccc2CCNCc2c1Cl	InChI=1S/C9H9Cl2N/c10-8-2-1-6-3-4-12-5-7(6)9(8)11/h1-2,12H,3-5H2	WFPUBEDBBOGGIQ-UHFFFAOYSA-N	13014	7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydrochloride::7,8-dichloro-1,2,3,4-tetrahydroisoquinoline::CHEMBL287837::CHEMBL541797::SKF 64139::tetrahydroisoquinoline (THIQ) analogue	Alpha-2A adrenergic receptor		 6520								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13014&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SKA	1YZ3	123920	46509415	160129	CHEMBL541797CHEMBL287837	DB08550			ZINC24714117	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295407	FC(F)(F)C1Cc2ccc(Br)cc2CN1	InChI=1S/C10H9BrF3N/c11-8-2-1-6-4-9(10(12,13)14)15-5-7(6)3-8/h1-3,9,15H,4-5H2	PEEKNBLYJJEHJI-UHFFFAOYSA-N	50079902	7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoquinoline::7-bromo-3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL112964	Alpha-2A adrenergic receptor		 4350								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079902	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079902&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10401405	103972016		CHEMBL112964				ZINC26985028	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295409	NS(=O)(=O)c1ccc2CCNCc2c1	InChI=1S/C9H12N2O2S/c10-14(12,13)9-2-1-7-3-4-11-6-8(7)5-9/h1-2,5,11H,3-4,6H2,(H2,10,12,13)	UGLLZXSYRBMNOS-UHFFFAOYSA-N	13017	1,2,3,4-tetrahydroisoquinoline-7-sulfonamide::CHEMBL26717::SKF 29661	Alpha-2A adrenergic receptor		 3400								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13017&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SKF	1HNN	5226	46513441		CHEMBL26717	DB03468			ZINC20397736	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295416	[O-][N+](=O)c1ccc2CCNCc2c1	InChI=1S/C9H10N2O2/c12-11(13)9-2-1-7-3-4-10-6-8(7)5-9/h1-2,5,10H,3-4,6H2	YPRWYZSUBZXORL-UHFFFAOYSA-N	50072991	7-Nitro-1,2,3,4-tetrahydro-isoquinoline::7-nitro-1,2,3,4-tetrahydroisoquinoline::CHEMBL281289	Alpha-2A adrenergic receptor		 3200								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072991&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6424833	103966506		CHEMBL281289				ZINC13686846	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295417	[O-][N+](=O)c1ccc2CC(NCc2c1)C(F)(F)F	InChI=1S/C10H9F3N2O2/c11-10(12,13)9-4-6-1-2-8(15(16)17)3-7(6)5-14-9/h1-3,9,14H,4-5H2	AZEWYBRFBDWZGW-UHFFFAOYSA-N	50079900	7-Nitro-3-trifluoromethyl-1,2,3,4-tetrahydro-isoquinoline::7-nitro-3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL112351	Alpha-2A adrenergic receptor		 3400								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079900	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079900&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10332138	103972014		CHEMBL112351				ZINC13686931	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50295421	[O-][N+](=O)c1ccc2CC(NCc2c1)C(F)F	InChI=1S/C10H10F2N2O2/c11-10(12)9-4-6-1-2-8(14(15)16)3-7(6)5-13-9/h1-3,9-10,13H,4-5H2	UCPKZVRFLFELDS-UHFFFAOYSA-N	50160906	(+/-)-3-difluoromethyl-7-nitro-1,2,3,4-tetrahydroisoquinoline::3-Difluoromethyl-7-nitro-1,2,3,4-tetrahydro-isoquinoline::CHEMBL182376	Alpha-2A adrenergic receptor		 3600								ChEMBL	10.1016/j.bmcl.2004.12.013	10.7270/Q2X63MFG	15686930			Grunewald, GL; Romero, FA; Seim, MR; Criscione, KR; Deupree, JD; Spackman, CC; Bylund, DB	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160906	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160906&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11608298	104047344		CHEMBL182376				ZINC13686921	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301903	CC(=O)N1C[C@H]2[C@H](CN3CCN(CCC\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C28H34N4O2/c1-22(33)32-20-25-27(34-29-28(25)24-13-7-8-14-26(24)32)21-31-18-16-30(17-19-31)15-9-3-6-12-23-10-4-2-5-11-23/h2,4-8,10-14,25,27H,3,9,15-21H2,1H3/b12-6+/t25-,27-/m0/s1	SNBRKKJCZXXNNL-MRGGPSPGSA-N	50163469	1-{(3R,3aR)-3-[4-((E)-5-Phenyl-pent-4-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-isoxazolo[4,3-c]quinolin-5-yl}-ethanone::CHEMBL426959	Alpha-2A adrenergic receptor		 47								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163469&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44387798	104049469		CHEMBL426959				ZINC28116712	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301911	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC(=O)c4ccncc4)ccc32)CC1)=C/c1ccccc1	InChI=1S/C31H32N4O4/c1-22(17-23-5-3-2-4-6-23)19-34-13-15-35(16-14-34)20-29-27-21-37-28-18-25(7-8-26(28)30(27)33-39-29)38-31(36)24-9-11-32-12-10-24/h2-12,17-18,27,29H,13-16,19-21H2,1H3/b22-17+/t27-,29-/m0/s1	OLAGLCHGSUYVBF-HXSUMWGRSA-N	50163474	CHEMBL425324::Isonicotinic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yl ester	Alpha-2A adrenergic receptor		 1								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163474&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11318438	104049474		CHEMBL425324				ZINC28111658	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301924	COCCOc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C28H35N3O4/c1-21(16-22-6-4-3-5-7-22)18-30-10-12-31(13-11-30)19-27-25-20-34-26-17-23(33-15-14-32-2)8-9-24(26)28(25)29-35-27/h3-9,16-17,25,27H,10-15,18-20H2,1-2H3/b21-16+/t25-,27-/m0/s1	VGYOOEDZRKNLKS-ZXDVGYGBSA-N	50163477	(3R,3aS)-7-(2-Methoxy-ethoxy)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL435352	Alpha-2A adrenergic receptor		 0.100000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163477&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11306100	104049477		CHEMBL435352				ZINC22582175	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301936	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC(=O)C=C)ccc32)CC1)=C/c1ccccc1	InChI=1S/C28H31N3O4/c1-3-27(32)34-22-9-10-23-25(16-22)33-19-24-26(35-29-28(23)24)18-31-13-11-30(12-14-31)17-20(2)15-21-7-5-4-6-8-21/h3-10,15-16,24,26H,1,11-14,17-19H2,2H3/b20-15+/t24-,26-/m0/s1	QHCZSHHKZDDCEC-MSKIIMLESA-N	50163487	Acrylic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-ylester::CHEMBL180322	Alpha-2A adrenergic receptor		 0.900000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163487&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11260018	104049487		CHEMBL180322				ZINC22933305	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301945	COCC(=O)Oc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C28H33N3O5/c1-20(14-21-6-4-3-5-7-21)16-30-10-12-31(13-11-30)17-26-24-18-34-25-15-22(35-27(32)19-33-2)8-9-23(25)28(24)29-36-26/h3-9,14-15,24,26H,10-13,16-19H2,1-2H3/b20-14+/t24-,26-/m0/s1	DISVZQSFAXIOLP-FAPZGSLLSA-N	50163491	CHEMBL175853::Methoxy-acetic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yl ester	Alpha-2A adrenergic receptor		 0.700000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163491&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11214030	104049491		CHEMBL175853				ZINC22933299	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301946	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC(=O)C4CC4)ccc32)CC1)=C/c1ccccc1	InChI=1S/C29H33N3O4/c1-20(15-21-5-3-2-4-6-21)17-31-11-13-32(14-12-31)18-27-25-19-34-26-16-23(35-29(33)22-7-8-22)9-10-24(26)28(25)30-36-27/h2-6,9-10,15-16,22,25,27H,7-8,11-14,17-19H2,1H3/b20-15+/t25-,27-/m0/s1	COPXFRMTXFPQKE-JZACSLLISA-N	50163483	CHEMBL175911::Cyclopropanecarboxylic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yl ester	Alpha-2A adrenergic receptor		 0.900000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163483&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11785068	104049483		CHEMBL175911				ZINC22933302	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301958	Fc1ccc2CC(CC3CNC=N3)Cc2c1	InChI=1S/C13H15FN2/c14-12-2-1-10-3-9(4-11(10)6-12)5-13-7-15-8-16-13/h1-2,6,8-9,13H,3-5,7H2,(H,15,16)	HBMJQYDGBNSZMC-UHFFFAOYSA-N	50131357	4-(5-Fluoro-indan-2-ylmethyl)-4,5-dihydro-1H-imidazole::CHEMBL90997::S-34324	Alpha-2A adrenergic receptor		 5.9								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131357&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220053	104022541		CHEMBL90997				ZINC26652869	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301959	CCOCCOCCOc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C31H41N3O5/c1-3-35-15-16-36-17-18-37-26-9-10-27-29(20-26)38-23-28-30(39-32-31(27)28)22-34-13-11-33(12-14-34)21-24(2)19-25-7-5-4-6-8-25/h4-10,19-20,28,30H,3,11-18,21-23H2,1-2H3/b24-19+/t28-,30-/m0/s1	LLFVSLMMRPXQFK-FPHSVDBKSA-N	50163475	(3R,3aS)-7-[2-(2-Ethoxy-ethoxy)-ethoxy]-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL179237	Alpha-2A adrenergic receptor		 1.3								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163475&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11785961	104049475		CHEMBL179237				ZINC28117339	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301963	COc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C26H31N3O3/c1-19(14-20-6-4-3-5-7-20)16-28-10-12-29(13-11-28)17-25-23-18-31-24-15-21(30-2)8-9-22(24)26(23)27-32-25/h3-9,14-15,23,25H,10-13,16-18H2,1-2H3/b19-14+/t23-,25-/m0/s1	UHVQVIBBKZFOBO-XDFBZRTDSA-N	50163494	(3R,3aS)-7-Methoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL176002	Alpha-2A adrenergic receptor		 0.500000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163494&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44387789	104049494		CHEMBL176002				ZINC22933286	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301965	COCCCOc1cc(ccc1OC)C(=O)N(C[C@@H]1CNC[C@H]1OC(=O)NCc1ccccc1)C(C)C	InChI=1S/C28H39N3O6/c1-20(2)31(27(32)22-11-12-24(35-4)25(15-22)36-14-8-13-34-3)19-23-17-29-18-26(23)37-28(33)30-16-21-9-6-5-7-10-21/h5-7,9-12,15,20,23,26,29H,8,13-14,16-19H2,1-4H3,(H,30,33)/t23-,26+/m0/s1	WGHJKYWWSVIRLL-JYFHCDHNSA-N	50065660	CHEMBL3403995	Alpha-2A adrenergic receptor			 1000							ChEMBL	10.1016/j.bmcl.2015.02.040	10.7270/Q2RF5WPJ	25754490			Sellner, H; Cottens, S; Cumin, F; Ehrhardt, C; Kosaka, T; Lorthiois, E; Ostermann, N; Webb, RL; Rigel, DF; Wagner, T; Maibaum, J	Novartis Pharma AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065660&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	3ZN	4RZ1	59271992	313071486		CHEMBL3403995					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301973	CN(C)CCOc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C29H38N4O3/c1-22(17-23-7-5-4-6-8-23)19-32-11-13-33(14-12-32)20-28-26-21-35-27-18-24(34-16-15-31(2)3)9-10-25(27)29(26)30-36-28/h4-10,17-18,26,28H,11-16,19-21H2,1-3H3/b22-17+/t26-,28-/m0/s1	NCOXQFRYWWZGEM-GRDZPNQDSA-N	50163479	CHEMBL176261::Dimethyl-(2-{(3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yloxy}-ethyl)-amine	Alpha-2A adrenergic receptor		 0.100000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163479&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11271808	104049479		CHEMBL176261				ZINC22582179	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301976	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(O)ccc32)CC1)=C/c1ccccc1	InChI=1S/C25H29N3O3/c1-18(13-19-5-3-2-4-6-19)15-27-9-11-28(12-10-27)16-24-22-17-30-23-14-20(29)7-8-21(23)25(22)26-31-24/h2-8,13-14,22,24,29H,9-12,15-17H2,1H3/b18-13+/t22-,24-/m0/s1	UCFVOQSSWZQWNE-ZCIIVOIYSA-N	50163468	(3R,3aS)-3-[4-((E)-2-Methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-ol::CHEMBL180470	Alpha-2A adrenergic receptor		 0.200000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163468&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11384600	104049468		CHEMBL180470				ZINC22933289	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301979	COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12	InChI=1S/C23H27NO2/c1-24(13-11-17-9-10-18-12-14-26-23(18)15-17)16-19-5-3-7-21-20(19)6-4-8-22(21)25-2/h4,6,8-10,12,14-15,19H,3,5,7,11,13,16H2,1-2H3/t19-/m0/s1	MHPMXTGKTXJIDI-IBGZPJMESA-N	50057128	(2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amine::A-80426::CHEMBL268258	Alpha-2A adrenergic receptor		 2.5								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057128&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9928332	103953208		CHEMBL268258				ZINC03810797	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50301996	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC4CCCC4)ccc32)CC1)=C/c1ccccc1	InChI=1S/C30H37N3O3/c1-22(17-23-7-3-2-4-8-23)19-32-13-15-33(16-14-32)20-29-27-21-34-28-18-25(35-24-9-5-6-10-24)11-12-26(28)30(27)31-36-29/h2-4,7-8,11-12,17-18,24,27,29H,5-6,9-10,13-16,19-21H2,1H3/b22-17+/t27-,29-/m0/s1	RJLMZCSOGDTDNJ-HXSUMWGRSA-N	50163498	(3R,3aS)-7-Cyclopentyloxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL369378	Alpha-2A adrenergic receptor		 1.3								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163498&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11190988	104049498		CHEMBL369378				ZINC22933290	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50302013	CC(=O)Oc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C27H31N3O4/c1-19(14-21-6-4-3-5-7-21)16-29-10-12-30(13-11-29)17-26-24-18-32-25-15-22(33-20(2)31)8-9-23(25)27(24)28-34-26/h3-9,14-15,24,26H,10-13,16-18H2,1-2H3/b19-14+/t24-,26-/m0/s1	AYMCTBRVXPCORT-DPAPPHFXSA-N	50163489	Acetic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-ylester::CHEMBL176116	Alpha-2A adrenergic receptor		 0.400000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163489&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11259744	104049489		CHEMBL176116				ZINC22933293	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50302018	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC(=O)C(C)(C)C)ccc32)CC1)=C/c1ccccc1	InChI=1S/C30H37N3O4/c1-21(16-22-8-6-5-7-9-22)18-32-12-14-33(15-13-32)19-27-25-20-35-26-17-23(36-29(34)30(2,3)4)10-11-24(26)28(25)31-37-27/h5-11,16-17,25,27H,12-15,18-20H2,1-4H3/b21-16+/t25-,27-/m0/s1	DGXYDPJRLWCWFV-ZXDVGYGBSA-N	50163484	2,2-Dimethyl-propionic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yl ester::CHEMBL178588	Alpha-2A adrenergic receptor		 4.7								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163484&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11191321	104049484		CHEMBL178588				ZINC22933308	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307407	CN(C)c1nc(NC2CCN(CC2)S(=O)(=O)c2ccc(Br)cc2OC(F)(F)F)nc2ccccc12	InChI=1S/C22H23BrF3N5O3S/c1-30(2)20-16-5-3-4-6-17(16)28-21(29-20)27-15-9-11-31(12-10-15)35(32,33)19-8-7-14(23)13-18(19)34-22(24,25)26/h3-8,13,15H,9-12H2,1-2H3,(H,27,28,29)	AUHFSEIMAYONHH-UHFFFAOYSA-N	50166556	CHEMBL360671::N*2*-[1-(4-Bromo-2-trifluoromethoxy-benzenesulfonyl)-piperidin-4-yl]-N*4*,N*4*-dimethyl-quinazoline-2,4-diamine	Alpha-2A adrenergic receptor			 170							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166556&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11342160	104052014		CHEMBL360671				ZINC28343413	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307415	CN(C)c1nc(NCC2CCC(CC2)NS(=O)(=O)c2ccc(Br)cc2OC(F)(F)F)nc2ccccc12	InChI=1S/C24H27BrF3N5O3S/c1-33(2)22-18-5-3-4-6-19(18)30-23(31-22)29-14-15-7-10-17(11-8-15)32-37(34,35)21-12-9-16(25)13-20(21)36-24(26,27)28/h3-6,9,12-13,15,17,32H,7-8,10-11,14H2,1-2H3,(H,29,30,31)	RYUJZKYTNJACIJ-UHFFFAOYSA-N	50166552	4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexyl}-2-trifluoromethoxy-benzenesulfonamide::CHEMBL193970	Alpha-2A adrenergic receptor			 21							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166552&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401616	104052010		CHEMBL193970				ZINC28523138	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307416	Nc1nc(NCC2CCC(CNS(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C23H25BrF3N5O3S/c24-16-9-10-20(19(11-16)35-23(25,26)27)36(33,34)30-13-15-7-5-14(6-8-15)12-29-22-31-18-4-2-1-3-17(18)21(28)32-22/h1-4,9-11,14-15,30H,5-8,12-13H2,(H3,28,29,31,32)	MHEKDRNEOKTABI-UHFFFAOYSA-N	50166554	CHEMBL192266::N-{4-[(4-Amino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-4-bromo-2-trifluoromethoxy-benzenesulfonamide	Alpha-2A adrenergic receptor			 100							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166554&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401591	104052012		CHEMBL192266				ZINC28520615	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307420	FC(F)(F)Oc1cc(Br)ccc1S(=O)(=O)NCC1CCC(CNc2ncc3ccccc3n2)CC1	InChI=1S/C23H24BrF3N4O3S/c24-18-9-10-21(20(11-18)34-23(25,26)27)35(32,33)30-13-16-7-5-15(6-8-16)12-28-22-29-14-17-3-1-2-4-19(17)31-22/h1-4,9-11,14-16,30H,5-8,12-13H2,(H,28,29,31)	BKDDSROSFZKQTN-UHFFFAOYSA-N	50166562	4-Bromo-N-[4-(quinazolin-2-ylaminomethyl)-cyclohexylmethyl]-2-trifluoromethoxy-benzenesulfonamide::CHEMBL425012	Alpha-2A adrenergic receptor			 140							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166562&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401552	104052020		CHEMBL425012				ZINC28523329	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307421	Nc1nc(NCC2CCC(CNS(=O)(=O)c3cccc4ccccc34)CC2)nc2ccccc12	InChI=1S/C26H29N5O2S/c27-25-22-9-3-4-10-23(22)30-26(31-25)28-16-18-12-14-19(15-13-18)17-29-34(32,33)24-11-5-7-20-6-1-2-8-21(20)24/h1-11,18-19,29H,12-17H2,(H3,27,28,30,31)	UULIGRNKXHCLQN-UHFFFAOYSA-N	50166561	CHEMBL195380::Naphthalene-1-sulfonic acid {4-[(4-amino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-amide	Alpha-2A adrenergic receptor			 97							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166561&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5312114	104052019		CHEMBL195380		1562		ZINC03828640	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307422	CN(C)c1nc(NC2CCC(CC2)NS(=O)(=O)c2ccc(Br)cc2OC(F)(F)F)nc2ccccc12	InChI=1S/C23H25BrF3N5O3S/c1-32(2)21-17-5-3-4-6-18(17)29-22(30-21)28-15-8-10-16(11-9-15)31-36(33,34)20-12-7-14(24)13-19(20)35-23(25,26)27/h3-7,12-13,15-16,31H,8-11H2,1-2H3,(H,28,29,30)	LDCMGLYXOOMRFQ-UHFFFAOYSA-N	50166563	4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-2-trifluoromethoxy-benzenesulfonamide::CHEMBL193771	Alpha-2A adrenergic receptor			 47							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166563&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11204090	104052021		CHEMBL193771				ZINC28334916	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307424	CN(C)c1nc(NC2CCC(CNS(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C24H27BrF3N5O3S/c1-33(2)22-18-5-3-4-6-19(18)31-23(32-22)30-17-10-7-15(8-11-17)14-29-37(34,35)21-12-9-16(25)13-20(21)36-24(26,27)28/h3-6,9,12-13,15,17,29H,7-8,10-11,14H2,1-2H3,(H,30,31,32)	GPEOXJGBWGMANI-UHFFFAOYSA-N	50166560	4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexylmethyl]-2-trifluoromethoxy-benzenesulfonamide::CHEMBL194602	Alpha-2A adrenergic receptor			 110							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166560&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11284878	104052018		CHEMBL194602				ZINC28336031	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307427	CN(C)c1nc(NCC2CCC(CNS(C)(=O)=O)CC2)nc2ccccc12	InChI=1S/C19H29N5O2S/c1-24(2)18-16-6-4-5-7-17(16)22-19(23-18)20-12-14-8-10-15(11-9-14)13-21-27(3,25)26/h4-7,14-15,21H,8-13H2,1-3H3,(H,20,22,23)	XPKLCTLEXRSJEM-UHFFFAOYSA-N	50166564	CHEMBL195123::N-{4-[(4-Dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-methanesulfonamide	Alpha-2A adrenergic receptor			 86							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166564&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401460	104052022		CHEMBL195123				ZINC28522841	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307429	CN(C)c1nc(NCC2CCN(CC2)S(=O)(=O)c2ccc(Br)cc2OC(F)(F)F)nc2ccccc12	InChI=1S/C23H25BrF3N5O3S/c1-31(2)21-17-5-3-4-6-18(17)29-22(30-21)28-14-15-9-11-32(12-10-15)36(33,34)20-8-7-16(24)13-19(20)35-23(25,26)27/h3-8,13,15H,9-12,14H2,1-2H3,(H,28,29,30)	UHHJLMKELWKRFM-UHFFFAOYSA-N	50166551	CHEMBL194173::N*2*-[1-(4-Bromo-2-trifluoromethoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-N*4*,N*4*-dimethyl-quinazoline-2,4-diamine	Alpha-2A adrenergic receptor			 5.6							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166551&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401671	104052009		CHEMBL194173				ZINC28523325	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307431	FC(F)(F)Oc1cc(Br)ccc1S(=O)(=O)NCC1CCC(CC1)Nc1ncc2ccccc2n1	InChI=1S/C22H22BrF3N4O3S/c23-16-7-10-20(19(11-16)33-22(24,25)26)34(31,32)28-12-14-5-8-17(9-6-14)29-21-27-13-15-3-1-2-4-18(15)30-21/h1-4,7,10-11,13-14,17,28H,5-6,8-9,12H2,(H,27,29,30)	NJWKXGIQDOFDKH-UHFFFAOYSA-N	50166557	4-Bromo-N-[4-(quinazolin-2-ylamino)-cyclohexylmethyl]-2-trifluoromethoxy-benzenesulfonamide::CHEMBL195810	Alpha-2A adrenergic receptor			 130							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166557&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401626	104052015		CHEMBL195810				ZINC28523101	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307432	FC(F)(F)Oc1cc(Br)ccc1S(=O)(=O)NC1CCC(CC1)Nc1ncc2ccccc2n1	InChI=1S/C21H20BrF3N4O3S/c22-14-5-10-19(18(11-14)32-21(23,24)25)33(30,31)29-16-8-6-15(7-9-16)27-20-26-12-13-3-1-2-4-17(13)28-20/h1-5,10-12,15-16,29H,6-9H2,(H,26,27,28)	JJQLRTKUCLCIPR-UHFFFAOYSA-N	50166565	4-Bromo-N-[4-(quinazolin-2-ylamino)-cyclohexyl]-2-trifluoromethoxy-benzenesulfonamide::CHEMBL195346	Alpha-2A adrenergic receptor			 57							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166565&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401449	104052023		CHEMBL195346				ZINC28523407	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307433	CN(C)c1nc(NCC2CCC(CNS(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C25H29BrF3N5O3S/c1-34(2)23-19-5-3-4-6-20(19)32-24(33-23)30-14-16-7-9-17(10-8-16)15-31-38(35,36)22-12-11-18(26)13-21(22)37-25(27,28)29/h3-6,11-13,16-17,31H,7-10,14-15H2,1-2H3,(H,30,32,33)	NWUCPBLQECHRFK-UHFFFAOYSA-N	50166555	4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzenesulfonamide::CHEMBL193438	Alpha-2A adrenergic receptor			 7.7							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166555&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9895868	104052013		CHEMBL193438				ZINC28332800	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50307444	CCCCS(=O)(=O)NCC1CCC(CNc2nc(N(C)C)c3ccccc3n2)CC1	InChI=1S/C22H35N5O2S/c1-4-5-14-30(28,29)24-16-18-12-10-17(11-13-18)15-23-22-25-20-9-7-6-8-19(20)21(26-22)27(2)3/h6-9,17-18,24H,4-5,10-16H2,1-3H3,(H,23,25,26)	RCMYMJSBSVKJNP-UHFFFAOYSA-N	50166559	Butane-1-sulfonic acid {4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-amide::CHEMBL193666	Alpha-2A adrenergic receptor			 58							ChEMBL	10.1016/j.bmcl.2005.03.052	10.7270/Q2Z89BXQ	15863317			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Beeley, N; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166559&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401508	104052017		CHEMBL193666				ZINC28523712	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50305567	COc1cc2CCN(C)C3Cc4cc5OCOc5cc4-c(c1OCc1ccc(Br)cc1)c23	InChI=1S/C26H24BrNO4/c1-28-8-7-16-10-23(29-2)26(30-13-15-3-5-18(27)6-4-15)25-19-12-22-21(31-14-32-22)11-17(19)9-20(28)24(16)25/h3-6,10-12,20H,7-9,13-14H2,1-2H3	AJIMVLSQIMXLNV-UHFFFAOYSA-N	50132341	CHEMBL3633757	Alpha-2A adrenergic receptor		<300								ChEMBL	10.1016/j.bmcl.2015.10.012	10.7270/Q2HD7XGH	26475518			Ponnala, S; Kapadia, N; Madapa, S; Alberts, IL; Harding, WW	City University of New York	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132341&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122195524	321903449		CHEMBL3633757					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50313266	Cn1c(c(C2CCCC2)c2ccc(cc12)C(=O)NC1(CCC1)C(=O)Nc1ccc(\C=C\C(O)=O)cc1)-c1ccccn1	InChI=1S/C34H34N4O4/c1-38-28-21-24(13-16-26(28)30(23-7-2-3-8-23)31(38)27-9-4-5-20-35-27)32(41)37-34(18-6-19-34)33(42)36-25-14-10-22(11-15-25)12-17-29(39)40/h4-5,9-17,20-21,23H,2-3,6-8,18-19H2,1H3,(H,36,42)(H,37,41)(H,39,40)/b17-12+	JBSNALXXNTWUEC-SFQUDFHCSA-N	50398052	CHEMBL2181776	Alpha-2A adrenergic receptor			<10000							ChEMBL	10.1016/j.bmcl.2014.12.078	10.7270/Q2M32XF0	25599836			Beaulieu, PL; Bolger, G; Deon, D; Duplessis, M; Fazal, G; Gagnon, A; Garneau, M; LaPlante, S; Stammers, T; Kukolj, G; Duan, J	Boehringer Ingelheim (Canada) Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398052&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56949326	163347076		CHEMBL2181776				ZINC95577431	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50319910	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 56								ChEMBL	10.1016/j.bmcl.2005.07.083	10.7270/Q2D799ZF	16153828			Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD	Chungbuk National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50319915	Cc1ccc(cc1)N(N=C1NCCN1)c1cccc(O)c1	InChI=1S/C16H18N4O/c1-12-5-7-13(8-6-12)20(19-16-17-9-10-18-16)14-3-2-4-15(21)11-14/h2-8,11,21H,9-10H2,1H3,(H2,17,18,19)	ONSCHPQYHGOIQX-UHFFFAOYSA-N	50173164	3-[N'-(4,5-Dihydro-1H-imidazol-2-yl)-N-p-tolyl-hydrazino]-phenol::CHEMBL194849	Alpha-2A adrenergic receptor		 24								ChEMBL	10.1016/j.bmcl.2005.07.083	10.7270/Q2D799ZF	16153828			Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD	Chungbuk National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173164&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9883506	104059135		CHEMBL194849				ZINC28526325	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50319922	COc1cccc(c1)N(N=C1NCCN1)c1ccc(C)cc1	InChI=1S/C17H20N4O/c1-13-6-8-14(9-7-13)21(20-17-18-10-11-19-17)15-4-3-5-16(12-15)22-2/h3-9,12H,10-11H2,1-2H3,(H2,18,19,20)	NEQHKSNFFVEGHN-UHFFFAOYSA-N	50173162	CHEMBL362954::N'-(4,5-Dihydro-1H-imidazol-2-yl)-N-(3-methoxy-phenyl)-N-p-tolyl-hydrazine	Alpha-2A adrenergic receptor		 6.3								ChEMBL	10.1016/j.bmcl.2005.07.083	10.7270/Q2D799ZF	16153828			Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD	Chungbuk National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173162&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11653915	104059133		CHEMBL362954				ZINC28526324	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50319923	COc1cccc(c1)N(N=C1NCCO1)c1ccc(C)cc1	InChI=1S/C17H19N3O2/c1-13-6-8-14(9-7-13)20(19-17-18-10-11-22-17)15-4-3-5-16(12-15)21-2/h3-9,12H,10-11H2,1-2H3,(H,18,19)	IOEIAXGHDJMROV-UHFFFAOYSA-N	50173165	CHEMBL194323::N'-(4,5-Dihydro-oxazol-2-yl)-N-(3-methoxy-phenyl)-N-p-tolyl-hydrazine	Alpha-2A adrenergic receptor		 4.2								ChEMBL	10.1016/j.bmcl.2005.07.083	10.7270/Q2D799ZF	16153828			Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD	Chungbuk National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173165&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44404321	104059136		CHEMBL194323				ZINC28526153	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50319926	Cc1ccc(cc1)N(N=C1NCCO1)c1cccc(O)c1	InChI=1S/C16H17N3O2/c1-12-5-7-13(8-6-12)19(18-16-17-9-10-21-16)14-3-2-4-15(20)11-14/h2-8,11,20H,9-10H2,1H3,(H,17,18)	HAIKGHUWKLUYNG-UHFFFAOYSA-N	50173163	3-[N'-(4,5-Dihydro-oxazol-2-yl)-N-p-tolyl-hydrazino]-phenol::CHEMBL370818	Alpha-2A adrenergic receptor		 4.7								ChEMBL	10.1016/j.bmcl.2005.07.083	10.7270/Q2D799ZF	16153828			Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD	Chungbuk National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173163&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44404326	104059134		CHEMBL370818				ZINC28526068	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50319275	Cl.NC[C@H]1C[C@@H]1c1cc(F)ccc1OCC=C	InChI=1S/C13H16FNO.ClH/c1-2-5-16-13-4-3-10(14)7-12(13)11-6-9(11)8-15;/h2-4,7,9,11H,1,5-6,8,15H2;1H/t9-,11+;/m1./s1	MNIAWGCBQVLINM-XQKZEKTMSA-N	50076240	CHEMBL3416063	Alpha-2A adrenergic receptor		<1000								ChEMBL	10.1021/jm5019274	10.7270/Q2BC4181	25633969			Cheng, J; Giguère, PM; Onajole, OK; Lv, W; Gaisin, A; Gunosewoyo, H; Schmerberg, CM; Pogorelov, VM; Rodriguiz, RM; Vistoli, G; Wetsel, WC; Roth, BL; Kozikowski, AP	University of Illinois at Chicago	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076240&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			92042918	103969173		CHEMBL3416063				ZINC34800561	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50319278	Cl.NC[C@H]1C[C@@H]1c1cc(F)ccc1OCCF	InChI=1S/C12H15F2NO.ClH/c13-3-4-16-12-2-1-9(14)6-11(12)10-5-8(10)7-15;/h1-2,6,8,10H,3-5,7,15H2;1H/t8-,10+;/m1./s1	RJWLRXULSMGYPC-SCYNACPDSA-N	50076244	CHEMBL3416067	Alpha-2A adrenergic receptor		<1000								ChEMBL	10.1021/jm5019274	10.7270/Q2BC4181	25633969			Cheng, J; Giguère, PM; Onajole, OK; Lv, W; Gaisin, A; Gunosewoyo, H; Schmerberg, CM; Pogorelov, VM; Rodriguiz, RM; Vistoli, G; Wetsel, WC; Roth, BL; Kozikowski, AP	University of Illinois at Chicago	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076244&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			92042920	103969177		CHEMBL3416067				ZINC34800582	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50333914	C[C@H](N)Cn1ncc2ccc(O)cc12	InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	WBYHTZYHAFNBKW-ZETCQYMHSA-N	50180251	1-((S)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL371300	Alpha-2A adrenergic receptor		 2270								ChEMBL	10.1021/jm050663x	10.7270/Q23B5ZQW	16392816			May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180251&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9834183	104065368		CHEMBL371300				ZINC00009096	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50333945	C[C@@H](N)Cn1ncc2ccc(O)cc12	InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m1/s1	WBYHTZYHAFNBKW-SSDOTTSWSA-N	50180256	1-((R)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL437314	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1021/jm050663x	10.7270/Q23B5ZQW	16392816			May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180256&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11500503	104065373		CHEMBL437314				ZINC13679044	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50337232	COc1cccc(c1)N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1	InChI=1S/C19H27N5O3/c1-21-18(25)15-20-24(19(21)26)9-4-3-8-22-10-12-23(13-11-22)16-6-5-7-17(14-16)27-2/h5-7,14-15H,3-4,8-13H2,1-2H3	PGGCRGAETLNAJC-UHFFFAOYSA-N	50182020	2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione::CHEMBL426317	Alpha-2A adrenergic receptor		 250								ChEMBL	10.1016/j.bmcl.2006.01.052	10.7270/Q2ZC82FS	16458504			Prabhakaran, J; Parsey, RV; Majo, VJ; Hsiung, SC; Milak, MS; Tamir, H; Simpson, NR; Van Heertum, RL; Mann, JJ; Dileep Kumar, JS	Columbia University College of Physicians and Surgeons	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182020&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11948707	104066846		CHEMBL426317				ZINC34801069	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50343661	OC1(CC2CCC(C1)N2CCCC(=O)c1ccc(F)cc1)c1ccc(Cl)cc1	InChI=1S/C23H25ClFNO2/c24-18-7-5-17(6-8-18)23(28)14-20-11-12-21(15-23)26(20)13-1-2-22(27)16-3-9-19(25)10-4-16/h3-10,20-21,28H,1-2,11-15H2	CXQUOFVDYCOSEZ-UHFFFAOYSA-N	50185473	4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2.1]octan-8-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-[3-(4-Chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL210578	Alpha-2A adrenergic receptor		 2835								ChEMBL	10.1016/j.bmcl.2006.03.057	10.7270/Q2571BM5	16621538			Ablordeppey, SY; Lyles-Eggleston, M; Bricker, B; Zhang, W; Zhu, X; Goodman, C; Roth, BL	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185473&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13091268	104069684		CHEMBL210578				ZINC12356279	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50343676	OC1(CCN(CCCC(=O)c2ccc(F)cc2)C1)c1ccc(Cl)cc1	InChI=1S/C20H21ClFNO2/c21-17-7-5-16(6-8-17)20(25)11-13-23(14-20)12-1-2-19(24)15-3-9-18(22)10-4-15/h3-10,25H,1-2,11-14H2	BETHXCLHMRGYBW-UHFFFAOYSA-N	50185474	(+)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::(-)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(-)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-pyrrolidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::CHEMBL150161	Alpha-2A adrenergic receptor		 2239								ChEMBL	10.1016/j.bmcl.2006.03.057	10.7270/Q2571BM5	16621538			Ablordeppey, SY; Lyles-Eggleston, M; Bricker, B; Zhang, W; Zhu, X; Goodman, C; Roth, BL	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185474&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9906978	104069685		CHEMBL150161				ZINC12356157	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50333317	COc1ccc2cccc(N3CCN(CCCCn4ncc(=O)n(C)c4=O)CC3)c2c1	InChI=1S/C23H29N5O3/c1-25-22(29)17-24-28(23(25)30)11-4-3-10-26-12-14-27(15-13-26)21-7-5-6-18-8-9-19(31-2)16-20(18)21/h5-9,16-17H,3-4,10-15H2,1-2H3	GKTQBPYMIGXPKG-UHFFFAOYSA-N	50180054	CHEMBL199824::[O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione	Alpha-2A adrenergic receptor		 1012								ChEMBL	10.1021/jm050725j	10.7270/Q2R49QBD	16392798			Kumar, JS; Majo, VJ; Hsiung, SC; Millak, MS; Liu, KP; Tamir, H; Prabhakaran, J; Simpson, NR; Van Heertum, RL; Mann, JJ; Parsey, RV	Columbia University College of Physicians and Surgeons	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180054&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10324985	104065192		CHEMBL199824				ZINC03825965	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50351779	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2c(C)cccc2N)c2ccccc12	InChI=1S/C26H27ClN6O/c1-17-6-5-8-20(28)24(17)26(34)30-33-22-9-4-3-7-19(22)25(32-14-12-31(2)13-15-32)29-21-16-18(27)10-11-23(21)33/h3-11,16H,12-15,28H2,1-2H3,(H,30,34)	SINCAXCRAGCJEY-UHFFFAOYSA-N	50190208	2-amino-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-6-methyl-benzamide::CHEMBL213424	Alpha-2A adrenergic receptor		 456								ChEMBL	10.1016/j.bmcl.2006.06.022	10.7270/Q2GT5MSW	16809034			Sasikumar, TK; Burnett, DA; Zhang, H; Smith-Torhan, A; Fawzi, A; Lachowicz, JE	Schering-Plough Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190208&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44415704	104073544		CHEMBL213424				ZINC34801072	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50351832	COc1cccc(OC)c1C(=O)NN1c2ccc(Cl)cc2N=C(N2CCN(C)CC2)c2ccccc12	InChI=1S/C27H28ClN5O3/c1-31-13-15-32(16-14-31)26-19-7-4-5-8-21(19)33(22-12-11-18(28)17-20(22)29-26)30-27(34)25-23(35-2)9-6-10-24(25)36-3/h4-12,17H,13-16H2,1-3H3,(H,30,34)	ADLYXAHODXNVQT-UHFFFAOYSA-N	50190059	CHEMBL425069::N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2,6-dimethoxy-benzamide	Alpha-2A adrenergic receptor		 169								ChEMBL	10.1016/j.bmcl.2006.06.022	10.7270/Q2GT5MSW	16809034			Sasikumar, TK; Burnett, DA; Zhang, H; Smith-Torhan, A; Fawzi, A; Lachowicz, JE	Schering-Plough Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190059	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190059&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44415569	104073481		CHEMBL425069				ZINC34801074	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50351833	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2c(C)cccc2C)c2ccccc12	InChI=1S/C27H28ClN5O/c1-18-7-6-8-19(2)25(18)27(34)30-33-23-10-5-4-9-21(23)26(32-15-13-31(3)14-16-32)29-22-17-20(28)11-12-24(22)33/h4-12,17H,13-16H2,1-3H3,(H,30,34)	IYRXIXGRSIJDNI-UHFFFAOYSA-N	50190062	CHEMBL213336::N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2,6-dimethyl-benzamide	Alpha-2A adrenergic receptor		 791								ChEMBL	10.1016/j.bmcl.2006.06.022	10.7270/Q2GT5MSW	16809034			Sasikumar, TK; Burnett, DA; Zhang, H; Smith-Torhan, A; Fawzi, A; Lachowicz, JE	Schering-Plough Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190062	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190062&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44415690	104073484		CHEMBL213336				ZINC34801076	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50351838	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2c(N)cccc2Cl)c2ccccc12	InChI=1S/C25H24Cl2N6O/c1-31-11-13-32(14-12-31)24-17-5-2-3-8-21(17)33(22-10-9-16(26)15-20(22)29-24)30-25(34)23-18(27)6-4-7-19(23)28/h2-10,15H,11-14,28H2,1H3,(H,30,34)	GPZGUIZYGOLWTO-UHFFFAOYSA-N	50190203	2-amino-6-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-benzamide::CHEMBL378669	Alpha-2A adrenergic receptor		 327								ChEMBL	10.1016/j.bmcl.2006.06.022	10.7270/Q2GT5MSW	16809034			Sasikumar, TK; Burnett, DA; Zhang, H; Smith-Torhan, A; Fawzi, A; Lachowicz, JE	Schering-Plough Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190203&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44415689	104073539		CHEMBL378669				ZINC34801075	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50351843	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2c(F)cccc2C(F)(F)F)c2ccccc12	InChI=1S/C26H22ClF4N5O/c1-34-11-13-35(14-12-34)24-17-5-2-3-8-21(17)36(22-10-9-16(27)15-20(22)32-24)33-25(37)23-18(26(29,30)31)6-4-7-19(23)28/h2-10,15H,11-14H2,1H3,(H,33,37)	FFNDTETUPMNYNN-UHFFFAOYSA-N	50190186	CHEMBL213492::N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2-fluoro-6-trifluoromethyl-benzamide	Alpha-2A adrenergic receptor		 2000								ChEMBL	10.1016/j.bmcl.2006.06.022	10.7270/Q2GT5MSW	16809034			Sasikumar, TK; Burnett, DA; Zhang, H; Smith-Torhan, A; Fawzi, A; Lachowicz, JE	Schering-Plough Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190186&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44415672	104073522		CHEMBL213492				ZINC34801077	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50351872	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2ccccc2Cl)c2ccccc12	InChI=1S/C25H23Cl2N5O/c1-30-12-14-31(15-13-30)24-19-7-3-5-9-22(19)32(23-11-10-17(26)16-21(23)28-24)29-25(33)18-6-2-4-8-20(18)27/h2-11,16H,12-15H2,1H3,(H,29,33)	DDNAXKKEJCCHMD-UHFFFAOYSA-N	50190049	2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-benzamide::CHEMBL212912	Alpha-2A adrenergic receptor		 455								ChEMBL	10.1016/j.bmcl.2006.06.022	10.7270/Q2GT5MSW	16809034			Sasikumar, TK; Burnett, DA; Zhang, H; Smith-Torhan, A; Fawzi, A; Lachowicz, JE	Schering-Plough Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190049	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190049&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16007117	104073471		CHEMBL212912				ZINC34801073	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50351873	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12	InChI=1S/C29H26ClN5O/c1-33-15-17-34(18-16-33)28-24-10-4-5-12-26(24)35(27-14-13-21(30)19-25(27)31-28)32-29(36)23-11-6-8-20-7-2-3-9-22(20)23/h2-14,19H,15-18H2,1H3,(H,32,36)	VTTMDSGFQMHASZ-UHFFFAOYSA-N	50190193	CHEMBL213834::naphthalene-1-carboxylic acid [8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-amide	Alpha-2A adrenergic receptor		 882								ChEMBL	10.1016/j.bmcl.2006.06.022	10.7270/Q2GT5MSW	16809034			Sasikumar, TK; Burnett, DA; Zhang, H; Smith-Torhan, A; Fawzi, A; Lachowicz, JE	Schering-Plough Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190193&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44415593	104073529		CHEMBL213834				ZINC34801071	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362061	Cc1nc2ccccc2c(Nc2ccc(cc2)N2CCN3CCCCC3C2)c1C	InChI=1S/C25H30N4/c1-18-19(2)26-24-9-4-3-8-23(24)25(18)27-20-10-12-21(13-11-20)29-16-15-28-14-6-5-7-22(28)17-29/h3-4,8-13,22H,5-7,14-17H2,1-2H3,(H,26,27)	MZAWJNSMQVUPQW-UHFFFAOYSA-N	50196109	(2,3-dimethylquinolin-4-yl)-[4-(octahydro-2H-pyrido[1,2-a]-pyrazin-2-yl)phenyl]amine::CHEMBL425983	Alpha-2A adrenergic receptor		 715								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196109&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10045713	104077985		CHEMBL425983				ZINC53255553	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362063	CN1CCN(CC1)c1ccc(Nc2ccnc3ccccc23)cc1	InChI=1S/C20H22N4/c1-23-12-14-24(15-13-23)17-8-6-16(7-9-17)22-20-10-11-21-19-5-3-2-4-18(19)20/h2-11H,12-15H2,1H3,(H,21,22)	RXXDJBWYJTWSKV-UHFFFAOYSA-N	50196110	CHEMBL217665::GNF-PF-2857::N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::[4-(4-methylpiperazin-1-yl)phenyl]quinolin-4-ylamine	Alpha-2A adrenergic receptor		 720								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196110&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4567175	104077986		CHEMBL217665				ZINC52962019	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362071	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3cc(Cl)ccc23)cc1	InChI=1S/C23H27ClN4O/c1-23(2)15-28(11-10-27(23)3)19-7-5-18(6-8-19)26-22-16(14-29)13-25-21-12-17(24)4-9-20(21)22/h4-9,12-13,29H,10-11,14-15H2,1-3H3,(H,25,26)	LCLUBKMUZSVUCV-UHFFFAOYSA-N	50196107	CHEMBL216464::{7-chloro-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2A adrenergic receptor		 960								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196107&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10251036	104077983		CHEMBL216464				ZINC34801089	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362079	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)c(C)nc3ccccc23)cc1	InChI=1S/C24H30N4O/c1-17-21(15-29)23(20-7-5-6-8-22(20)25-17)26-18-9-11-19(12-10-18)28-14-13-27(4)24(2,3)16-28/h5-12,29H,13-16H2,1-4H3,(H,25,26)	AANVRTGJCGRJSR-UHFFFAOYSA-N	50196123	CHEMBL218675::{2-methyl-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2A adrenergic receptor		 1170								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196123&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090630	104077999		CHEMBL218675				ZINC34801107	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362080	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)/t17-/m1/s1	LKVQAMHRWJYSED-QGZVFWFLSA-N	50196125	(R)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine::CHEMBL383978	Alpha-2A adrenergic receptor		 910								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196125&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090595	104078001		CHEMBL383978					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362081	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(CO)nc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-16-14-27(13-12-26(16)3)19-10-8-18(9-11-19)24-23-17(2)22(15-28)25-21-7-5-4-6-20(21)23/h4-11,16,28H,12-15H2,1-3H3,(H,24,25)/t16-/m1/s1	CWSVSBNTQJZFGE-MRXNPFEDSA-N	50196126	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-3-methylquinolin-2-yl}methanol::CHEMBL217254	Alpha-2A adrenergic receptor		 1870								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196126&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090601	104078002		CHEMBL217254				ZINC52962010	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362082	CCN1CCN(CC1)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1	InChI=1S/C25H26N4/c1-2-28-15-17-29(18-16-28)20-13-11-19(12-14-20)26-25-21-7-3-5-9-23(21)27-24-10-6-4-8-22(24)25/h3-14H,2,15-18H2,1H3,(H,26,27)	CUVBGWMAORETGV-UHFFFAOYSA-N	50196122	CHEMBL217366::GNF-PF-3878::N-(4-(4-ethylpiperazin-1-yl)phenyl)acridin-9-amine::TCMDC-124255	Alpha-2A adrenergic receptor		 3600								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196122&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3072540	104077998		CHEMBL217366				ZINC52962012	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362091	CC(C)c1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)CC1	InChI=1S/C24H30N4/c1-17(2)23-18(3)25-22-8-6-5-7-21(22)24(23)26-19-9-11-20(12-10-19)28-15-13-27(4)14-16-28/h5-12,17H,13-16H2,1-4H3,(H,25,26)	JLIOUCZCOQHOPO-UHFFFAOYSA-N	50196119	(3-isopropyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl]amine::CHEMBL425622	Alpha-2A adrenergic receptor		 1700								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196119&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10177445	104077995		CHEMBL425622				ZINC53255565	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362093	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-23(2)16-27(13-12-26(23)3)19-10-8-18(9-11-19)25-22-17(15-28)14-24-21-7-5-4-6-20(21)22/h4-11,14,28H,12-13,15-16H2,1-3H3,(H,24,25)	SASCGBIFSTWAKB-UHFFFAOYSA-N	50196118	CHEMBL268217::{4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol	Alpha-2A adrenergic receptor		 1850								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196118&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10474679	104077994		CHEMBL268217				ZINC34801106	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362095	CC1CN(CCN1C)c1ccc(Nc2c(C)cnc3ccccc23)cc1	InChI=1S/C22H26N4/c1-16-14-23-21-7-5-4-6-20(21)22(16)24-18-8-10-19(11-9-18)26-13-12-25(3)17(2)15-26/h4-11,14,17H,12-13,15H2,1-3H3,(H,23,24)	TVLLCWBBMXDYLI-UHFFFAOYSA-N	50196131	CHEMBL217202::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-methylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 1400								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196131&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090622	104078007		CHEMBL217202				ZINC52962005	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362096	Cc1nc2ccccc2c(Nc2ccc(NCCN3CCCC3)cc2)c1C	InChI=1S/C23H28N4/c1-17-18(2)25-22-8-4-3-7-21(22)23(17)26-20-11-9-19(10-12-20)24-13-16-27-14-5-6-15-27/h3-4,7-12,24H,5-6,13-16H2,1-2H3,(H,25,26)	QBONYGHVEVRMDD-UHFFFAOYSA-N	50196114	CHEMBL440594::N-(2,3-dimethylquinolin-4-yl)-N'-(2-pyrrolidin-1-ylethyl)benzene-1,4-diamine	Alpha-2A adrenergic receptor		 1000								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196114&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090600	104077990		CHEMBL440594				ZINC34801093	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362097	CN1CCN(CC1)c1ccc(Nc2c(C)cncc2C)cc1	InChI=1S/C18H24N4/c1-14-12-19-13-15(2)18(14)20-16-4-6-17(7-5-16)22-10-8-21(3)9-11-22/h4-7,12-13H,8-11H2,1-3H3,(H,19,20)	BDODJZYHQXXMMX-UHFFFAOYSA-N	50196133	(3,5-dimethyl-pyridin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl]amine::CHEMBL217180	Alpha-2A adrenergic receptor		 3600								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196133	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196133&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090634	104078009		CHEMBL217180				ZINC52634508	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362100	CN1CCN(CC1)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1	InChI=1S/C24H24N4/c1-27-14-16-28(17-15-27)19-12-10-18(11-13-19)25-24-20-6-2-4-8-22(20)26-23-9-5-3-7-21(23)24/h2-13H,14-17H2,1H3,(H,25,26)	QZKGUNQLVFEEBA-UHFFFAOYSA-N	50196135	Acridin-9-yl-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine::CHEMBL106525::GNF-Pf-3427::N-(4-(4-methylpiperazin-1-yl)phenyl)acridin-9-amine::TCMDC-123912	Alpha-2A adrenergic receptor		 3200								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196135&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			540335	104078011		CHEMBL106525		3930		ZINC53151259	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362101	CCc1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)CC1	InChI=1S/C23H28N4/c1-4-20-17(2)24-22-8-6-5-7-21(22)23(20)25-18-9-11-19(12-10-18)27-15-13-26(3)14-16-27/h5-12H,4,13-16H2,1-3H3,(H,24,25)	YEGLCEJPSSYEQE-UHFFFAOYSA-N	50196136	(3-ethyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL425803	Alpha-2A adrenergic receptor		 1100								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196136&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10109188	104078012		CHEMBL425803				ZINC53228274	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362102	CN1CCN(CC1)c1ccc(Nc2cc(C)nc3ccccc23)cc1	InChI=1S/C21H24N4/c1-16-15-21(19-5-3-4-6-20(19)22-16)23-17-7-9-18(10-8-17)25-13-11-24(2)12-14-25/h3-10,15H,11-14H2,1-2H3,(H,22,23)	MKIZKMFJTXEUHC-UHFFFAOYSA-N	50196137	CHEMBL216399::[4-(4-methylpiperazin-1-yl)phenyl]-(2-methylquinolin-4-yl)-amine	Alpha-2A adrenergic receptor		 500								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196137&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9923679	104078013		CHEMBL216399				ZINC52961945	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362103	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cccc(Cl)c23)cc1	InChI=1S/C23H27ClN4/c1-15-14-28(13-12-27(15)4)19-10-8-18(9-11-19)26-23-16(2)17(3)25-21-7-5-6-20(24)22(21)23/h5-11,15H,12-14H2,1-4H3,(H,25,26)	DZQRMYQZZBIVHO-UHFFFAOYSA-N	50196138	(5-chloro-2,3-dimethylquinolin-4-yl)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]amine::CHEMBL217568	Alpha-2A adrenergic receptor		 775								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196138&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090598	104078014		CHEMBL217568				ZINC52961987	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362104	CN1CCN(CC1(C)C)c1ccc(Nc2c(C)cnc3ccccc23)cc1	InChI=1S/C23H28N4/c1-17-15-24-21-8-6-5-7-20(21)22(17)25-18-9-11-19(12-10-18)27-14-13-26(4)23(2,3)16-27/h5-12,15H,13-14,16H2,1-4H3,(H,24,25)	RXEIREHXCVZQFP-UHFFFAOYSA-N	50196139	(3-methylquinolin-4-yl)-[4-(3,3,4-trimethylpiperazin-1-yl)phenyl]amine::CHEMBL218679	Alpha-2A adrenergic receptor		 895								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196139&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10473701	104078015		CHEMBL218679				ZINC34801110	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362106	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C22H26N4O/c1-16-14-26(12-11-25(16)2)19-9-7-18(8-10-19)24-22-17(15-27)13-23-21-6-4-3-5-20(21)22/h3-10,13,16,27H,11-12,14-15H2,1-2H3,(H,23,24)/t16-/m1/s1	FYGUXILZNQKUCD-MRXNPFEDSA-N	50196116	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol::CHEMBL217542	Alpha-2A adrenergic receptor		 2200								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196116&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090602	104077992		CHEMBL217542				ZINC13977226	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362109	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C23H27FN4O/c1-23(2)15-28(11-10-27(23)3)19-7-5-18(6-8-19)26-22-16(14-29)13-25-21-9-4-17(24)12-20(21)22/h4-9,12-13,29H,10-11,14-15H2,1-3H3,(H,25,26)	KJGIXOOWJYEMMO-UHFFFAOYSA-N	50196108	CHEMBL424917::{6-fluoro-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2A adrenergic receptor		 1320								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196108&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10475736	104077984		CHEMBL424917				ZINC34801088	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362113	CCc1c(C)nc2CCCCc2c1Nc1ccc(cc1)N1CCN(C)C(C)C1	InChI=1S/C24H34N4/c1-5-21-18(3)25-23-9-7-6-8-22(23)24(21)26-19-10-12-20(13-11-19)28-15-14-27(4)17(2)16-28/h10-13,17H,5-9,14-16H2,1-4H3,(H,25,26)	AWRXNUNJSQSZSP-UHFFFAOYSA-N	50196143	4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-ethyl-2-methyl-5,6,7,8-tetrahydroquinolin-4-yl)amine::CHEMBL217768	Alpha-2A adrenergic receptor		 630								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196143&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090635	104078019		CHEMBL217768				ZINC52962006	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362114	CC1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C22H25FN4O/c1-15-13-27(10-9-26(15)2)19-6-4-18(5-7-19)25-22-16(14-28)12-24-21-8-3-17(23)11-20(21)22/h3-8,11-12,15,28H,9-10,13-14H2,1-2H3,(H,24,25)	RLNXYUWOYNTOTQ-UHFFFAOYSA-N	50196115	CHEMBL276417::{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-6-fluoroquinolin-3-yl}methanol	Alpha-2A adrenergic receptor		 1380								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196115&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10317643	104077991		CHEMBL276417				ZINC53059380	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362122	C[C@@H]1CN(CCN1)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C21H24N4O/c1-15-13-25(11-10-22-15)18-8-6-17(7-9-18)24-21-16(14-26)12-23-20-5-3-2-4-19(20)21/h2-9,12,15,22,26H,10-11,13-14H2,1H3,(H,23,24)/t15-/m1/s1	MDMIXTNJRVJFQM-OAHLLOKOSA-N	50196134	(R)-{4-[4-(3-methylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol::CHEMBL385722	Alpha-2A adrenergic receptor		 9600								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196134	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196134&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090632	104078010		CHEMBL385722				ZINC53173570	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362124	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)	LKVQAMHRWJYSED-UHFFFAOYSA-N	50196113	CHEMBL262901::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 840								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196113&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10044968	104077989		CHEMBL262901				ZINC53033641	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362125	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3ccc(F)cc23)cc1	InChI=1S/C23H27FN4/c1-15-14-28(12-11-27(15)4)20-8-6-19(7-9-20)26-23-16(2)17(3)25-22-10-5-18(24)13-21(22)23/h5-10,13,15H,11-12,14H2,1-4H3,(H,25,26)	OGGREUDUNWRXNK-UHFFFAOYSA-N	50196120	CHEMBL216727::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(6-fluoro-2,3-dimethylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 1230								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196120&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090626	104077996		CHEMBL216727				ZINC52961958	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362127	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C22H25FN4O/c1-15-13-27(10-9-26(15)2)19-6-4-18(5-7-19)25-22-16(14-28)12-24-21-8-3-17(23)11-20(21)22/h3-8,11-12,15,28H,9-10,13-14H2,1-2H3,(H,24,25)/t15-/m1/s1	RLNXYUWOYNTOTQ-OAHLLOKOSA-N	50196127	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-6-fluoroquinolin-3-yl}methanol::CHEMBL214661	Alpha-2A adrenergic receptor		 980								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196127&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090633	104078003		CHEMBL214661					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362128	CCN(CC)CCNc1ccc(Nc2c(CC)c(C)nc3c(C)cccc23)cc1	InChI=1S/C25H34N4/c1-6-22-19(5)27-24-18(4)10-9-11-23(24)25(22)28-21-14-12-20(13-15-21)26-16-17-29(7-2)8-3/h9-15,26H,6-8,16-17H2,1-5H3,(H,27,28)	VWHNYSUZLOHFTG-UHFFFAOYSA-N	50196106	CHEMBL216197::N-(2-diethylaminoethyl)-N'-(3-ethyl-2,8-dimethylquinolin-4-yl)benzene-1,4-diamine	Alpha-2A adrenergic receptor		 900								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196106&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090627	104077982		CHEMBL216197				ZINC34801115	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362129	CN1CCCN(C1)c1ccc(Nc2c(C)c(C)nc3c(C)cccc23)cc1	InChI=1S/C23H28N4/c1-16-7-5-8-21-22(16)24-18(3)17(2)23(21)25-19-9-11-20(12-10-19)27-14-6-13-26(4)15-27/h5,7-12H,6,13-15H2,1-4H3,(H,24,25)	KUMLVCNUFRRWHR-UHFFFAOYSA-N	50196111	4-(3-methyltetrahydropyrimidin-1(2H)-yl)phenyl]-(2,3,8-trimethylquinolin-4-yl)amine::CHEMBL216072	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196111&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090599	104077987		CHEMBL216072				ZINC34801117	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362134	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)	OFZVRVWUVPCFQQ-UHFFFAOYSA-N	50196132	CHEMBL217203::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 1850								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196132&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10362866	104078008		CHEMBL217203				ZINC52961985	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362135	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)cccc23)cc1	InChI=1S/C24H30N4/c1-16-7-6-8-22-23(16)25-19(4)18(3)24(22)26-20-9-11-21(12-10-20)28-14-13-27(5)17(2)15-28/h6-12,17H,13-15H2,1-5H3,(H,25,26)	ONMSNZLMBSAGLW-UHFFFAOYSA-N	50196146	CHEMBL217177::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,8-trimethylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 1900								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196146&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090596	104078022		CHEMBL217177				ZINC52961981	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362139	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)cc(C)c23)cc1	InChI=1S/C25H32N4/c1-16-13-17(2)24-23(14-16)26-20(5)19(4)25(24)27-21-7-9-22(10-8-21)29-12-11-28(6)18(3)15-29/h7-10,13-14,18H,11-12,15H2,1-6H3,(H,26,27)	ISQPPFGYKGDIHL-UHFFFAOYSA-N	50196148	CHEMBL218730::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5,7-tetramethylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 650								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196148&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11741010	104078024		CHEMBL218730				ZINC52971517	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362140	C[C@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)/t17-/m0/s1	LKVQAMHRWJYSED-KRWDZBQOSA-N	50196140	(S)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine::CHEMBL217278	Alpha-2A adrenergic receptor		 1050								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196140&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090624	104078016		CHEMBL217278				ZINC52962028	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362143	CN1CCN(CC1)c1ccc(Nc2c(C)c(C)nc3ccccc23)cc1	InChI=1S/C22H26N4/c1-16-17(2)23-21-7-5-4-6-20(21)22(16)24-18-8-10-19(11-9-18)26-14-12-25(3)13-15-26/h4-11H,12-15H2,1-3H3,(H,23,24)	YAPCYKZPQAMZQI-UHFFFAOYSA-N	50196141	(2,3-dimethylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl] amine::CHEMBL267464	Alpha-2A adrenergic receptor		 2210								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196141&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10132386	104078017		CHEMBL267464				ZINC53050145	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362145	CCc1c(C)nc2c(C)cccc2c1Nc1ccc(cc1)N1CCCN(C)CC1	InChI=1S/C25H32N4/c1-5-22-19(3)26-24-18(2)8-6-9-23(24)25(22)27-20-10-12-21(13-11-20)29-15-7-14-28(4)16-17-29/h6,8-13H,5,7,14-17H2,1-4H3,(H,26,27)	HWDFFRKTRBIVTK-UHFFFAOYSA-N	50196147	(3-ethyl-2,8-dimethylquinolin-4-yl)-[4-(4-methyl-[1,4]diazepan-1-yl)phenyl]amine::CHEMBL386169	Alpha-2A adrenergic receptor		 8000								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196147&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090628	104078023		CHEMBL386169				ZINC34801087	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362146	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)ccc(C)c23)cc1	InChI=1S/C25H32N4/c1-16-7-8-17(2)24-23(16)25(19(4)20(5)26-24)27-21-9-11-22(12-10-21)29-14-13-28(6)18(3)15-29/h7-12,18H,13-15H2,1-6H3,(H,26,27)	KTKKHYOEEDBCLW-UHFFFAOYSA-N	50196112	CHEMBL384318::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5,8-tetramethylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 2300								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196112&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090597	104077988		CHEMBL384318				ZINC53173617	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362154	CC(O)c1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)C(C)C1	InChI=1S/C24H30N4O/c1-16-15-28(14-13-27(16)4)20-11-9-19(10-12-20)26-24-21-7-5-6-8-22(21)25-17(2)23(24)18(3)29/h5-12,16,18,29H,13-15H2,1-4H3,(H,25,26)	VIFJNFUXJIBEDW-UHFFFAOYSA-N	50196117	1-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}ethanol::CHEMBL217253	Alpha-2A adrenergic receptor		 3100								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196117&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090631	104077993		CHEMBL217253				ZINC52962008	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362156	CN1CCN(CC1)c1ccc(Nc2c(Cc3ccccc3)c(C)nc3ccccc23)cc1	InChI=1S/C28H30N4/c1-21-26(20-22-8-4-3-5-9-22)28(25-10-6-7-11-27(25)29-21)30-23-12-14-24(15-13-23)32-18-16-31(2)17-19-32/h3-15H,16-20H2,1-2H3,(H,29,30)	CNOXIXMPZLKURQ-UHFFFAOYSA-N	50196128	(3-benzyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL384925	Alpha-2A adrenergic receptor		 580								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196128&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090621	104078004		CHEMBL384925				ZINC53173678	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362161	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cccc(C)c23)cc1	InChI=1S/C24H30N4/c1-16-7-6-8-22-23(16)24(18(3)19(4)25-22)26-20-9-11-21(12-10-20)28-14-13-27(5)17(2)15-28/h6-12,17H,13-15H2,1-5H3,(H,25,26)	JLEBPSNYUGYMNN-UHFFFAOYSA-N	50196121	CHEMBL217452::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5-trimethylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 680								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196121&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090625	104077997		CHEMBL217452				ZINC52962030	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362164	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)/t17-/m1/s1	OFZVRVWUVPCFQQ-QGZVFWFLSA-N	50196145	(R)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine::CHEMBL217567	Alpha-2A adrenergic receptor		 790								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196145&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090623	104078021		CHEMBL217567					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362178	CC1CN(CCN1C)c1ccc(Nc2c(c(C)nc3ccccc23)-c2ccccc2)cc1	InChI=1S/C28H30N4/c1-20-19-32(18-17-31(20)3)24-15-13-23(14-16-24)30-28-25-11-7-8-12-26(25)29-21(2)27(28)22-9-5-4-6-10-22/h4-16,20H,17-19H2,1-3H3,(H,29,30)	IJXRJXMYHWPNMW-UHFFFAOYSA-N	50196142	CHEMBL218457::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2-methyl-3-phenylquinolin-4-yl)amine	Alpha-2A adrenergic receptor		 1400								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196142&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10070896	104078018		CHEMBL218457				ZINC13977224	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362179	CC1CN(CCN1C)c1ccc(Nc2c(CO)c(C)nc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-16-14-27(13-12-26(16)3)19-10-8-18(9-11-19)25-23-20-6-4-5-7-22(20)24-17(2)21(23)15-28/h4-11,16,28H,12-15H2,1-3H3,(H,24,25)	BSEZBDDBKUJHQP-UHFFFAOYSA-N	50196129	CHEMBL214996::{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}methanol	Alpha-2A adrenergic receptor		 3100								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196129&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10045088	104078005		CHEMBL214996				ZINC52961856	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362181	CN1CCN(CC1)c1ccc(Nc2c(c(C)nc3ccccc23)-c2ccccc2)cc1	InChI=1S/C27H28N4/c1-20-26(21-8-4-3-5-9-21)27(24-10-6-7-11-25(24)28-20)29-22-12-14-23(15-13-22)31-18-16-30(2)17-19-31/h3-15H,16-19H2,1-2H3,(H,28,29)	YRMKSXYNMSJIBT-UHFFFAOYSA-N	50196130	(2-methyl-3-phenylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL216290	Alpha-2A adrenergic receptor		 1700								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196130&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10319299	104078006		CHEMBL216290				ZINC52961950	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50362186	C[C@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)/t17-/m0/s1	OFZVRVWUVPCFQQ-KRWDZBQOSA-N	50196124	(S)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine::CHEMBL216674	Alpha-2A adrenergic receptor		 850								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196124&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090594	104078000		CHEMBL216674				ZINC52961971	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50390247	FCc1nc(cs1)C#Cc1cc(F)cc(c1)C#N	InChI=1S/C13H6F2N2S/c14-6-13-17-12(8-18-13)2-1-9-3-10(7-16)5-11(15)4-9/h3-5,8H,6H2	WTLBLIGPXACYET-UHFFFAOYSA-N	50215552	3-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile::CHEMBL229429	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm0701268	10.7270/Q2FB52NB	17571866			Simeon, FG; Brown, AK; Zoghbi, SS; Patterson, VM; Innis, RB; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215552&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16737207	104090124		CHEMBL229429		6434		ZINC28701631	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50386431	Cc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12	InChI=1S/C19H24N4O4S/c1-13-17-7-6-16(11-18(17)22-21-13)27-9-8-20-12-19(24)14-4-3-5-15(10-14)23-28(2,25)26/h3-7,10-11,19-20,23-24H,8-9,12H2,1-2H3,(H,21,22)/t19-/m0/s1	ITIDAHAJICCYKL-IBGZPJMESA-N	50108094	CHEMBL3601200	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1021/acs.jmedchem.5b00638	10.7270/Q2NG4SDR	26125514			Wada, Y; Shirahashi, H; Iwanami, T; Ogawa, M; Nakano, S; Morimoto, A; Kasahara, K; Tanaka, E; Takada, Y; Ohashi, S; Mori, M; Shuto, S	Asahi Kasei Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108094&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10135864	104003316		CHEMBL3601200				ZINC13471866	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50401690	COc1cc2C(CN(C)C3Cc4cc5OCOc5cc4-c(c1OC)c23)c1ccccc1	InChI=1S/C26H25NO4/c1-27-13-19(15-7-5-4-6-8-15)18-12-23(28-2)26(29-3)25-17-11-22-21(30-14-31-22)10-16(17)9-20(27)24(18)25/h4-8,10-12,19-20H,9,13-14H2,1-3H3	XYYAWEJOUNEPTR-UHFFFAOYSA-N	50114872	CHEMBL3608450	Alpha-2A adrenergic receptor		 719								ChEMBL	10.1016/j.bmcl.2015.07.012	10.7270/Q2MW2JXN	26227772			Kapadia, N; Harding, WW	City University of New York	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114872&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122186880	319493993		CHEMBL3608450					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50404996	CCCN1CCO[C@@H](C1)c1cccc(O)c1	InChI=1S/C13H19NO2/c1-2-6-14-7-8-16-13(10-14)11-4-3-5-12(15)9-11/h3-5,9,13,15H,2,6-8,10H2,1H3/t13-/m0/s1	WYEGTIGJSHGEID-ZDUSSCGKSA-N	50226008	(R)-3-(4-propylmorpholin-2-yl)phenol::CHEMBL250403	Alpha-2A adrenergic receptor		>1000								ChEMBL	10.1016/j.bmcl.2007.10.059	10.7270/Q23J3CQ5	17976986			Blagg, J; Allerton, CM; Batchelor, DV; Baxter, AD; Burring, DJ; Carr, CL; Cook, AS; Nichols, CL; Phipps, J; Sanderson, VG; Verrier, H; Wong, S	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226008&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9794475	104096944		CHEMBL250403				ZINC26822913	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50427907	C[C@@H](Oc1cccc(Cn2c(C)c(C(=O)c3ccc(Cl)cc3)c3ccc(OC(F)(F)F)cc23)c1)C(O)=O	InChI=1S/C27H21ClF3NO5/c1-15-24(25(33)18-6-8-19(28)9-7-18)22-11-10-21(37-27(29,30)31)13-23(22)32(15)14-17-4-3-5-20(12-17)36-16(2)26(34)35/h3-13,16H,14H2,1-2H3,(H,34,35)/t16-/m1/s1	DHUATBAZHILHIC-MRXNPFEDSA-N	50244809	(2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy]propanoicAcid::(R)-2-(3-((3-(4-chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl)methyl)phenoxy)propanoic acid::CHEMBL461571	Alpha-2A adrenergic receptor			 1650							ChEMBL	10.1016/j.bmcl.2008.07.103	10.7270/Q2BC3ZC5	18701276			Debenham, SD; Chan, A; Lau, FW; Liu, W; Wood, HB; Lemme, K; Colwell, L; Habulihaz, B; Akiyama, TE; Einstein, M; Doebber, TW; Sharma, N; Wang, CF; Wu, M; Berger, JP; Meinke, PT	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50244809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50244809&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44190762	104100737		CHEMBL461571				ZINC03942600	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50431378	CNC(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1	InChI=1S/C28H31ClN2O2/c1-30-26(32)28(23-8-4-2-5-9-23,24-10-6-3-7-11-24)18-21-31-19-16-27(33,17-20-31)22-12-14-25(29)15-13-22/h2-15,33H,16-21H2,1H3,(H,30,32)	ZMOPTLXEYOVARP-UHFFFAOYSA-N	50253754	4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-methyl-2,2-diphenylbutanamide::CHEMBL1627	Alpha-2A adrenergic receptor		 1								ChEMBL	10.1021/jm800510m	10.7270/Q2BV7GFM	18783208			Lazarova, N; Zoghbi, SS; Hong, J; Seneca, N; Tuan, E; Gladding, RL; Liow, JS; Taku, A; Innis, RB; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253754&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9805944	104106206	64043	CHEMBL1627				ZINC21981239	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50433243	CN(C)CCCOc1ccc(CCNC(=O)c2cc(Br)c[nH]2)cc1Br	InChI=1S/C18H23Br2N3O2/c1-23(2)8-3-9-25-17-5-4-13(10-15(17)20)6-7-21-18(24)16-11-14(19)12-22-16/h4-5,10-12,22H,3,6-9H2,1-2H3,(H,21,24)	MOWCGUQGNSAZSR-UHFFFAOYSA-N	50253285	4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phenethyl)-1H-pyrrole-2-carboxamide::CHEMBL493091::N-(3-bromo-4-(3-(dimethylamino)propoxy)phenethyl)-4-bromo-1H-pyrrole-2-carboxamide	Alpha-2A adrenergic receptor		 69								ChEMBL	10.1021/np800339e	10.7270/Q2QZ29SK	18800848			Kennedy, JP; Brogan, JT; Lindsley, CW	Vanderbilt University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253285&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16215415	104105842		CHEMBL493091				ZINC15122204	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50433244	CN(C)CCCOc1ccc(CCNC(=O)c2cc(Br)c[nH]2)cc1Br	InChI=1S/C18H23Br2N3O2/c1-23(2)8-3-9-25-17-5-4-13(10-15(17)20)6-7-21-18(24)16-11-14(19)12-22-16/h4-5,10-12,22H,3,6-9H2,1-2H3,(H,21,24)	MOWCGUQGNSAZSR-UHFFFAOYSA-N	50253285	4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phenethyl)-1H-pyrrole-2-carboxamide::CHEMBL493091::N-(3-bromo-4-(3-(dimethylamino)propoxy)phenethyl)-4-bromo-1H-pyrrole-2-carboxamide	Alpha-2A adrenergic receptor			 185							ChEMBL	10.1021/np800339e	10.7270/Q2QZ29SK	18800848			Kennedy, JP; Brogan, JT; Lindsley, CW	Vanderbilt University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253285&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16215415	104105842		CHEMBL493091				ZINC15122204	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432755	O=C(NCCN1CCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C27H30N4O4/c32-26(23-9-6-12-29-27(23)35-21-7-2-1-3-8-21)28-13-14-30-15-17-31(18-16-30)19-22-20-33-24-10-4-5-11-25(24)34-22/h1-12,22H,13-20H2,(H,28,32)	SJTUPIJPFNBFHK-UHFFFAOYSA-N	50263620	CHEMBL478026::N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)piperazin-1-yl)ethyl)-2-phenoxynicotinamide	Alpha-2A adrenergic receptor		 27								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263620&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579186	104111893		CHEMBL478026				ZINC40406768	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432760	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1	InChI=1S/C22H28N4O3/c27-22(18-5-3-8-23-15-18)24-9-12-25-10-4-11-26(14-13-25)16-19-17-28-20-6-1-2-7-21(20)29-19/h1-3,5-8,15,19H,4,9-14,16-17H2,(H,24,27)	POCXNIFHHUXWMU-UHFFFAOYSA-N	50263674	CHEMBL476774::N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide	Alpha-2A adrenergic receptor		 443								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263674&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579231	104111927		CHEMBL476774				ZINC40916962	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432761	C(CN1CCCN(CC2COc3ccccc3O2)CC1)OCc1cccnc1Oc1ccccc1	InChI=1S/C28H33N3O4/c1-2-9-24(10-3-1)35-28-23(8-6-13-29-28)21-32-19-18-30-14-7-15-31(17-16-30)20-25-22-33-26-11-4-5-12-27(26)34-25/h1-6,8-13,25H,7,14-22H2	AFRRMVBYOMNLHN-UHFFFAOYSA-N	50263724	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-((2-phenoxypyridin-3-yl)methoxy)ethyl)-1,4-diazepane::CHEMBL491419	Alpha-2A adrenergic receptor		 66								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263724&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579271	104111963		CHEMBL491419				ZINC45498778	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432762	C(C1COc2ccccc2O1)N1CCCN(Cc2nc(no2)-c2cccnc2Oc2ccccc2)CC1	InChI=1S/C28H29N5O4/c1-2-8-21(9-3-1)36-28-23(10-6-13-29-28)27-30-26(37-31-27)19-33-15-7-14-32(16-17-33)18-22-20-34-24-11-4-5-12-25(24)35-22/h1-6,8-13,22H,7,14-20H2	YWALOGYVALOLTL-UHFFFAOYSA-N	50263725	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-((3-(2-phenoxypyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)-1,4-diazepane::CHEMBL491420	Alpha-2A adrenergic receptor		 45								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263725&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579272	104111964		CHEMBL491420				ZINC40424119	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432763	C(C1CCc2ccccc2O1)N1CCN(Cc2ccccc2)CC1	InChI=1S/C21H26N2O/c1-2-6-18(7-3-1)16-22-12-14-23(15-13-22)17-20-11-10-19-8-4-5-9-21(19)24-20/h1-9,20H,10-17H2	AJZBPCAHQHCXMX-UHFFFAOYSA-N	50159018	1-Benzyl-4-chroman-2-ylmethyl-piperazine::1-benzyl-4-((3,4-dihydro-2H-chromen-2-yl)methyl)piperazine::CHEMBL179648	Alpha-2A adrenergic receptor		 146								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159018&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10758200	104045618		CHEMBL179648				ZINC22445891	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432764	C(C1COc2ccccc2C1)N1CCN(Cc2ccccc2)CC1	InChI=1S/C21H26N2O/c1-2-6-18(7-3-1)15-22-10-12-23(13-11-22)16-19-14-20-8-4-5-9-21(20)24-17-19/h1-9,19H,10-17H2	QDCUYFUPXSPBMW-UHFFFAOYSA-N	50159021	1-Benzyl-4-chroman-3-ylmethyl-piperazine::1-benzyl-4-((3,4-dihydro-2H-chromen-3-yl)methyl)piperazine::CHEMBL362699	Alpha-2A adrenergic receptor		>500								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159021&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11338418	104045621		CHEMBL362699				ZINC22933155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432786	COc1ccccc1N1CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C20H24N2O3/c1-23-18-7-3-2-6-17(18)22-12-10-21(11-13-22)14-16-15-24-19-8-4-5-9-20(19)25-16/h2-9,16H,10-15H2,1H3	IQDINXFLUAYBCC-UHFFFAOYSA-N	50263618	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-methoxyphenyl)piperazine::CHEMBL518592	Alpha-2A adrenergic receptor		 167								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263618&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579184	104111891		CHEMBL518592				ZINC20775759	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432787	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)	RNPCOHCWKNMBRI-UHFFFAOYSA-N	50263619	CHEMBL477816::N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)-2-phenoxynicotinamide	Alpha-2A adrenergic receptor		 474								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263619&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579185	104111892		CHEMBL477816				ZINC40421976	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432788	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1cccc(c1)C#N	InChI=1S/C29H31N5O4/c30-19-22-6-3-7-23(18-22)38-29-25(8-4-11-32-29)28(35)31-12-15-33-13-5-14-34(17-16-33)20-24-21-36-26-9-1-2-10-27(26)37-24/h1-4,6-11,18,24H,5,12-17,20-21H2,(H,31,35)	YGAFMXXNJBOVBA-UHFFFAOYSA-N	50263621	2-(3-cyanophenoxy)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL515331	Alpha-2A adrenergic receptor		 501								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263621&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579187	104111894		CHEMBL515331				ZINC40918054	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432789	CC(C)(C)Nc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H37N5O3/c1-26(2,3)29-24-21(8-6-11-27-24)25(32)28-12-15-30-13-7-14-31(17-16-30)18-20-19-33-22-9-4-5-10-23(22)34-20/h4-6,8-11,20H,7,12-19H2,1-3H3,(H,27,29)(H,28,32)	IPSCUIDJZTXJJO-UHFFFAOYSA-N	50263671	2-(tert-butylamino)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL477608	Alpha-2A adrenergic receptor		 366								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263671&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579228	104111924		CHEMBL477608				ZINC40916745	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432790	CCCCOc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H36N4O4/c1-2-3-18-32-26-22(8-6-11-28-26)25(31)27-12-15-29-13-7-14-30(17-16-29)19-21-20-33-23-9-4-5-10-24(23)34-21/h4-6,8-11,21H,2-3,7,12-20H2,1H3,(H,27,31)	OYOGQACTFBHTOD-UHFFFAOYSA-N	50263672	2-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL514837	Alpha-2A adrenergic receptor		 74								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263672&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579229	104111925		CHEMBL514837				ZINC40408846	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432791	CCCCOc1cccc(n1)C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H36N4O4/c1-2-3-18-32-25-11-6-8-22(28-25)26(31)27-12-15-29-13-7-14-30(17-16-29)19-21-20-33-23-9-4-5-10-24(23)34-21/h4-6,8-11,21H,2-3,7,12-20H2,1H3,(H,27,31)	RVIXAJHMKWFIKC-UHFFFAOYSA-N	50263673	6-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)picolinamide::CHEMBL476569	Alpha-2A adrenergic receptor		 48								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263673&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579230	104111926		CHEMBL476569				ZINC40917448	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50432795	O=C(NCCN1CCCN(C[C@H]2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)/t23-/m0/s1	RNPCOHCWKNMBRI-QHCPKHFHSA-N	50263774	(S)-N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide::CHEMBL524153	Alpha-2A adrenergic receptor		>442								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263774&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25110718	104111991		CHEMBL524153				ZINC40951657	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456467	Fc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19FN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	ALTKABGEMCJWJH-UHFFFAOYSA-N	50140053	CHEMBL3754496	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140053&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127026052	104029803		CHEMBL3754496				ZINC28224295	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456468	Clc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19ClN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	XRJGWSMTLAFHBN-UHFFFAOYSA-N	50140054	CHEMBL3752900	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140054&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036932	104029804		CHEMBL3752900				ZINC28225245	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456469	Brc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19BrN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	JWPAYBAIIARWMG-UHFFFAOYSA-N	50140055	CHEMBL3754166	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140055&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036953	104029805		CHEMBL3754166				ZINC28224430	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456470	Cc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C17H22N2/c1-4-9-19(10-5-2)11-8-15-13-18-17-7-6-14(3)12-16(15)17/h4-7,12-13,18H,1-2,8-11H2,3H3	HTDIOUCPOHFDQH-UHFFFAOYSA-N	50140056	CHEMBL3753318	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140056&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036186	104029806		CHEMBL3753318				ZINC36311031	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456471	COc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C17H22N2O/c1-4-9-19(10-5-2)11-8-14-13-18-17-7-6-15(20-3)12-16(14)17/h4-7,12-13,18H,1-2,8-11H2,3H3	HGRHWEAUHXYNNP-UHFFFAOYSA-N	50435344	CHEMBL2391541	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50435344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50435344&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50878551	175447661		CHEMBL2391541				ZINC40448582	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456472	Fc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19FN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	ALTKABGEMCJWJH-UHFFFAOYSA-N	50140053	CHEMBL3754496	Alpha-2A adrenergic receptor		 117								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140053&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127026052	104029803		CHEMBL3754496				ZINC28224295	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456473	Clc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19ClN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	XRJGWSMTLAFHBN-UHFFFAOYSA-N	50140054	CHEMBL3752900	Alpha-2A adrenergic receptor		 81								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140054&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036932	104029804		CHEMBL3752900				ZINC28225245	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456638	COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccc(F)cc2)CC1	InChI=1S/C23H29F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18,22,27H,9-16H2,1H3	QCFZUTYIUYQTPW-UHFFFAOYSA-N	50232152	(1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroethoxy)-2-methoxyphenyl)methanol::(3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::CHEMBL402143	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmc.2009.03.021	10.7270/Q21V5DW2	19329329			Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rosch, F	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50232152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50232152&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44455426	104055426		CHEMBL402143				ZINC29128987	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456639	COc1c(OCCF)cccc1[C@H](O)C1CCN(CCc2ccc(F)cc2)CC1	InChI=1S/C23H29F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18,22,27H,9-16H2,1H3/t22-/m1/s1	QCFZUTYIUYQTPW-JOCHJYFZSA-N	50267507	(R)-(3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::CHEMBL515472	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmc.2009.03.021	10.7270/Q21V5DW2	19329329			Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rosch, F	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50267507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50267507&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44582675	104114317		CHEMBL515472				ZINC29128987	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456640	COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1	InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	HVJOIRMQZXEGPW-UHFFFAOYSA-N	50267508	4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fluorophenylethyl)-piperidine::CHEMBL516088	Alpha-2A adrenergic receptor		 863								ChEMBL	10.1016/j.bmc.2009.03.021	10.7270/Q21V5DW2	19329329			Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rosch, F	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50267508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50267508&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44582676	104114318		CHEMBL516088				ZINC40918122	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456641	COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccc(C)cc2)CC1	InChI=1S/C24H32FNO3/c1-18-6-8-19(9-7-18)10-14-26-15-11-20(12-16-26)23(27)21-4-3-5-22(24(21)28-2)29-17-13-25/h3-9,20,23,27H,10-17H2,1-2H3	MJKRYUCQHJLOIV-UHFFFAOYSA-N	50267510	(3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluylphenylethyl)-piperidine-4-yl)-methanol::CHEMBL476839	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmc.2009.03.021	10.7270/Q21V5DW2	19329329			Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rosch, F	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50267510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50267510&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44582678	104114320		CHEMBL476839				ZINC40402851	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456793	C=CCN(CCc1c[nH]c2ccccc12)CC=C	InChI=1S/C16H20N2/c1-3-10-18(11-4-2)12-9-14-13-17-16-8-6-5-7-15(14)16/h3-8,13,17H,1-2,9-12H2	LQEATNFJCMVKAC-UHFFFAOYSA-N	50140058	CHEMBL3752576	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140058&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24839550	104029808		CHEMBL3752576				ZINC36311040	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456795	Brc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19BrN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	JWPAYBAIIARWMG-UHFFFAOYSA-N	50140055	CHEMBL3754166	Alpha-2A adrenergic receptor		 83								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140055&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036953	104029805		CHEMBL3754166				ZINC28224430	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456796	Cc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C17H22N2/c1-4-9-19(10-5-2)11-8-15-13-18-17-7-6-14(3)12-16(15)17/h4-7,12-13,18H,1-2,8-11H2,3H3	HTDIOUCPOHFDQH-UHFFFAOYSA-N	50140056	CHEMBL3753318	Alpha-2A adrenergic receptor		 195								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140056&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036186	104029806		CHEMBL3753318				ZINC36311031	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456797	COc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C17H22N2O/c1-4-9-19(10-5-2)11-8-14-13-18-17-7-6-15(20-3)12-16(14)17/h4-7,12-13,18H,1-2,8-11H2,3H3	HGRHWEAUHXYNNP-UHFFFAOYSA-N	50435344	CHEMBL2391541	Alpha-2A adrenergic receptor		 214								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50435344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50435344&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50878551	175447661		CHEMBL2391541				ZINC40448582	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50456800	C=CCN(CCc1c[nH]c2ccccc12)CC=C	InChI=1S/C16H20N2/c1-3-10-18(11-4-2)12-9-14-13-17-16-8-6-5-7-15(14)16/h3-8,13,17H,1-2,9-12H2	LQEATNFJCMVKAC-UHFFFAOYSA-N	50140058	CHEMBL3752576	Alpha-2A adrenergic receptor		 123								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140058&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24839550	104029808		CHEMBL3752576				ZINC36311040	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459475	COCc1c2CC[C@@H](c3ncc[nH]3)c2ccc1Cl	InChI=1S/C14H15ClN2O/c1-18-8-12-10-2-3-11(14-16-6-7-17-14)9(10)4-5-13(12)15/h4-7,11H,2-3,8H2,1H3,(H,16,17)/t11-/m1/s1	CMNAOKMSNCWOHS-LLVKDONJSA-N	50256563	(R)-2-(5-chloro-4-(methoxymethyl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole::CHEMBL481322	Alpha-2A adrenergic receptor		>1700								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50256563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50256563&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44593557	104107998		CHEMBL481322				ZINC40936745	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459479	N#Cc1ccccc1[C@@H]1Cc2nccn2C1	InChI=1S/C13H11N3/c14-8-10-3-1-2-4-12(10)11-7-13-15-5-6-16(13)9-11/h1-6,11H,7,9H2/t11-/m1/s1	KMOFNRDXTFJLAO-LLVKDONJSA-N	50258517	(S)-2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)benzonitrile::CHEMBL466046	Alpha-2A adrenergic receptor		>4500								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258517&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574044	104109167		CHEMBL466046				ZINC40394468	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459483	C1[C@H](Cn2ccnc12)c1ccccc1-c1ccccc1	InChI=1S/C18H16N2/c1-2-6-14(7-3-1)16-8-4-5-9-17(16)15-12-18-19-10-11-20(18)13-15/h1-11,15H,12-13H2/t15-/m1/s1	NGKTVUYBFUWABZ-OAHLLOKOSA-N	50258518	(S)-6-(biphenyl-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL512062	Alpha-2A adrenergic receptor		 213								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258518&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574045	104109168		CHEMBL512062				ZINC40394655	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459487	C1[C@H](Cn2ccnc12)c1ccccc1-c1cncnc1	InChI=1S/C16H14N4/c1-2-4-15(13-8-17-11-18-9-13)14(3-1)12-7-16-19-5-6-20(16)10-12/h1-6,8-9,11-12H,7,10H2/t12-/m1/s1	OUQNCXBFEAQBPY-GFCCVEGCSA-N	50258559	(S)-6-(2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL513691	Alpha-2A adrenergic receptor		>3800								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258559&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574074	104109200		CHEMBL513691				ZINC40394709	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459491	C1[C@H](Cn2ccnc12)c1ccccc1-c1ncco1	InChI=1S/C15H13N3O/c1-2-4-13(15-17-6-8-19-15)12(3-1)11-9-14-16-5-7-18(14)10-11/h1-8,11H,9-10H2/t11-/m1/s1	MIWWMVGPFZMLEG-LLVKDONJSA-N	50258560	(S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)oxazole::CHEMBL448802	Alpha-2A adrenergic receptor		 805								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258560&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574075	104109201		CHEMBL448802				ZINC40979456	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459495	C1[C@@H](Cn2ccnc12)c1ccccc1-c1ncco1	InChI=1S/C15H13N3O/c1-2-4-13(15-17-6-8-19-15)12(3-1)11-9-14-16-5-7-18(14)10-11/h1-8,11H,9-10H2/t11-/m0/s1	MIWWMVGPFZMLEG-NSHDSACASA-N	50258561	(R)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)oxazole::CHEMBL448147	Alpha-2A adrenergic receptor		 1020								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258561&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574076	104109202		CHEMBL448147				ZINC40980726	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459500	CNC(=O)c1cccc(c1)-c1ccccc1[C@@H]1Cc2nccn2C1	InChI=1S/C20H19N3O/c1-21-20(24)15-6-4-5-14(11-15)17-7-2-3-8-18(17)16-12-19-22-9-10-23(19)13-16/h2-11,16H,12-13H2,1H3,(H,21,24)/t16-/m1/s1	PIDATBLWKGYAEW-MRXNPFEDSA-N	50258592	(S)-2'-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-N-methylbiphenyl-3-carboxamide::CHEMBL466012	Alpha-2A adrenergic receptor		 202								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258592&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574106	104109229		CHEMBL466012				ZINC40395829	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459504	Fc1ccc(C2Cc3nccn3C2)c(c1)-c1cncnc1	InChI=1S/C16H13FN4/c17-13-1-2-14(11-5-16-20-3-4-21(16)9-11)15(6-13)12-7-18-10-19-8-12/h1-4,6-8,10-11H,5,9H2	LOWJTSZIULCLQH-UHFFFAOYSA-N	50258593	6-(4-fluoro-2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL505414	Alpha-2A adrenergic receptor		>2370								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258593&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574107	104109230		CHEMBL505414				ZINC40378956	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459508	Fc1ccc(-c2cncnc2)c(c1)C1Cc2nccn2C1	InChI=1S/C16H13FN4/c17-13-1-2-14(12-7-18-10-19-8-12)15(6-13)11-5-16-20-3-4-21(16)9-11/h1-4,6-8,10-11H,5,9H2	VQAGIJGIBIOPGW-UHFFFAOYSA-N	50258594	6-(5-fluoro-2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL506744	Alpha-2A adrenergic receptor		>2780								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258594&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44219718	104109231		CHEMBL506744				ZINC40834510	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459512	Fc1cccc(-c2cncnc2)c1C1Cc2nccn2C1	InChI=1S/C16H13FN4/c17-14-3-1-2-13(12-7-18-10-19-8-12)16(14)11-6-15-20-4-5-21(15)9-11/h1-5,7-8,10-11H,6,9H2	MXXSIQQCMWZCJR-UHFFFAOYSA-N	50258638	6-(2-fluoro-6-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL467259	Alpha-2A adrenergic receptor		>3310								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258638&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574132	104109264		CHEMBL467259				ZINC40875467	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459516	Fc1ccc(C2Cc3nccn3C2)c(c1)-c1ncco1	InChI=1S/C15H12FN3O/c16-11-1-2-12(13(8-11)15-18-4-6-20-15)10-7-14-17-3-5-19(14)9-10/h1-6,8,10H,7,9H2	BFDKAMOCQFIESP-UHFFFAOYSA-N	50258639	2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-5-fluorophenyl)oxazole::CHEMBL501404	Alpha-2A adrenergic receptor		>2160								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258639&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574133	104109265		CHEMBL501404				ZINC40979741	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459520	Fc1ccc(-c2ncco2)c(c1)C1Cc2nccn2C1	InChI=1S/C15H12FN3O/c16-11-1-2-12(15-18-4-6-20-15)13(8-11)10-7-14-17-3-5-19(14)9-10/h1-6,8,10H,7,9H2	NOCWBSIDJYRURZ-UHFFFAOYSA-N	50258640	2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-4-fluorophenyl)oxazole::CHEMBL466634	Alpha-2A adrenergic receptor		 469								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258640&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574134	104109266		CHEMBL466634				ZINC40395348	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459524	Fc1ccc(C2Cc3nccn3C2)c(c1)-c1cc[nH]n1	InChI=1S/C15H13FN4/c16-11-1-2-12(13(8-11)14-3-4-18-19-14)10-7-15-17-5-6-20(15)9-10/h1-6,8,10H,7,9H2,(H,18,19)	BXJSKCZBNVAQEJ-UHFFFAOYSA-N	50258641	6-(4-fluoro-2-(1H-pyrazol-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL511211	Alpha-2A adrenergic receptor		 1470								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258641&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574135	104109267		CHEMBL511211				ZINC40875175	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459533	Fc1ccc(C2Cc3nccn3C2)c(c1)-n1cccn1	InChI=1S/C15H13FN4/c16-12-2-3-13(14(9-12)20-6-1-4-18-20)11-8-15-17-5-7-19(15)10-11/h1-7,9,11H,8,10H2	PUGMNVJZHKJJKF-UHFFFAOYSA-N	50258644	6-(4-fluoro-2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL466635	Alpha-2A adrenergic receptor		>3230								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258644&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574138	104109270		CHEMBL466635				ZINC40395350	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459536	C1[C@H](Cn2ccnc12)c1ccccc1-c1ccncc1	InChI=1S/C17H15N3/c1-2-4-16(14-11-17-19-9-10-20(17)12-14)15(3-1)13-5-7-18-8-6-13/h1-10,14H,11-12H2/t14-/m1/s1	PEIDTOAIWXQRBC-CQSZACIVSA-N	50258564	(S)-6-(2-(pyridin-4-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL512289	Alpha-2A adrenergic receptor		 112								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258564&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574079	104109205		CHEMBL512289				ZINC40896558	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459538	Cn1cc(cn1)-c1ccccc1[C@@H]1Cc2nccn2C1	InChI=1S/C16H16N4/c1-19-10-13(9-18-19)15-5-3-2-4-14(15)12-8-16-17-6-7-20(16)11-12/h2-7,9-10,12H,8,11H2,1H3/t12-/m1/s1	QUSFXAATAPEOAD-GFCCVEGCSA-N	50258565	(S)-6-(2-(1-methyl-1H-pyrazol-4-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL508084	Alpha-2A adrenergic receptor		 380								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258565&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574080	104109206		CHEMBL508084				ZINC40379757	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459542	C1[C@H](Cn2ccnc12)c1ccccc1-n1cccn1	InChI=1S/C15H14N4/c1-2-5-14(19-8-3-6-17-19)13(4-1)12-10-15-16-7-9-18(15)11-12/h1-9,12H,10-11H2/t12-/m1/s1	IPPGENORPYHMGX-GFCCVEGCSA-N	50258589	(S)-6-(2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL448908	Alpha-2A adrenergic receptor		 1100								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258589&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574103	104109226		CHEMBL448908				ZINC40379317	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459546	CS(=O)(=O)Nc1cccc(c1)-c1ccccc1[C@@H]1Cc2nccn2C1	InChI=1S/C19H19N3O2S/c1-25(23,24)21-16-6-4-5-14(11-16)17-7-2-3-8-18(17)15-12-19-20-9-10-22(19)13-15/h2-11,15,21H,12-13H2,1H3/t15-/m1/s1	FKMTZJPWARGCCN-OAHLLOKOSA-N	50258590	(S)-N-(2'-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)biphenyl-3-yl)methanesulfonamide::CHEMBL513871	Alpha-2A adrenergic receptor		 114								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258590&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574104	104109227		CHEMBL513871				ZINC40895634	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459550	CNS(=O)(=O)CCc1ccccc1[C@@H]1Cc2nccn2C1	InChI=1S/C15H19N3O2S/c1-16-21(19,20)9-6-12-4-2-3-5-14(12)13-10-15-17-7-8-18(15)11-13/h2-5,7-8,13,16H,6,9-11H2,1H3/t13-/m1/s1	FQZYLYAFBBAGRL-CYBMUJFWSA-N	50258591	(S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)-N-methylethanesulfonamide::CHEMBL469127	Alpha-2A adrenergic receptor		 280								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258591&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574105	104109228		CHEMBL469127				ZINC40895637	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459551	C1[C@H](Cn2ccnc12)c1ccccc1-c1nccs1	InChI=1S/C15H13N3S/c1-2-4-13(15-17-6-8-19-15)12(3-1)11-9-14-16-5-7-18(14)10-11/h1-8,11H,9-10H2/t11-/m1/s1	IXNQNKUBBRFMIS-LLVKDONJSA-N	50258562	(S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)thiazole::CHEMBL468710	Alpha-2A adrenergic receptor		 1750								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258562&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574077	104109203		CHEMBL468710				ZINC40892743	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50459555	C1[C@H](Cn2ccnc12)c1ccccc1-c1cccnc1	InChI=1S/C17H15N3/c1-2-6-16(14-10-17-19-8-9-20(17)12-14)15(5-1)13-4-3-7-18-11-13/h1-9,11,14H,10,12H2/t14-/m1/s1	JVQZWPGHLBOWKN-CQSZACIVSA-N	50258563	(S)-6-(2-(pyridin-3-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL468711	Alpha-2A adrenergic receptor		 991								ChEMBL	10.1016/j.bmcl.2009.03.166	10.7270/Q2WS8T5T	19414260			Roberts, LR; Fish, PV; Ian Storer, R; Whitlock, GA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258563&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574078	104109204		CHEMBL468711				ZINC40394710	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50458552	C1C(Cc2ccccc12)c1ncc[nH]1	InChI=1S/C12H12N2/c1-2-4-10-8-11(7-9(10)3-1)12-13-5-6-14-12/h1-6,11H,7-8H2,(H,13,14)	KMKRWMBSKDDVCW-UHFFFAOYSA-N	50259332	2-(2,3-dihydro-1H-inden-2-yl)-1H-imidazole::CHEMBL449279	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2009.03.162	10.7270/Q2R78F42	19394220			Whitlock, GA; Brennan, PE; Roberts, LR; Stobie, A	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259332&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44574834	104109641		CHEMBL449279				ZINC40846218	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50458553	C1Cc2nc[nH]c2CC1c1ccccc1	InChI=1S/C13H14N2/c1-2-4-10(5-3-1)11-6-7-12-13(8-11)15-9-14-12/h1-5,9,11H,6-8H2,(H,14,15)	FNAMNTIDTBOHMV-UHFFFAOYSA-N	50259333	6-phenyl-4,5,6,7-tetra hydro-1H-benzo[d]imidazole::6-phenyl-4,5,6,7-tetrahydro-1H-benzo[d]imidazole::CHEMBL466296	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2009.03.162	10.7270/Q2R78F42	19394220			Whitlock, GA; Brennan, PE; Roberts, LR; Stobie, A	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259333&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44593577	104109642		CHEMBL466296				ZINC40874880	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50458558	C1C(Cn2ccnc12)c1ccccc1	InChI=1S/C12H12N2/c1-2-4-10(5-3-1)11-8-12-13-6-7-14(12)9-11/h1-7,11H,8-9H2	SQVDOAJVRQASHO-UHFFFAOYSA-N	50259381	6-phenyl-6,7-di hydro-5H-pyrrolo[1,2-a]imidazole::6-phenyl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL465963	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2009.03.162	10.7270/Q2R78F42	19394220			Whitlock, GA; Brennan, PE; Roberts, LR; Stobie, A	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259381&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12764879	104109679		CHEMBL465963				ZINC39281877	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50458559	C1Cc2nccn2CC1c1ccccc1	InChI=1S/C13H14N2/c1-2-4-11(5-3-1)12-6-7-13-14-8-9-15(13)10-12/h1-5,8-9,12H,6-7,10H2	BZMHRUWVNNKWDQ-UHFFFAOYSA-N	50259382	6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine::CHEMBL466914	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2009.03.162	10.7270/Q2R78F42	19394220			Whitlock, GA; Brennan, PE; Roberts, LR; Stobie, A	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259382&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12764880	104109680		CHEMBL466914				ZINC39281879	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50471057	Cl.NCC1CC1c1cc(F)c(F)cc1OCC=C	InChI=1S/C13H15F2NO.ClH/c1-2-3-17-13-6-12(15)11(14)5-10(13)9-4-8(9)7-16;/h2,5-6,8-9H,1,3-4,7,16H2;1H	XGCOQOYOBQPELW-UHFFFAOYSA-N	50148852	CHEMBL3769968	Alpha-2A adrenergic receptor		 166								ChEMBL	10.1021/acs.jmedchem.5b01153	10.7270/Q28C9Z4P	26704965			Cheng, J; Giguere, PM; Schmerberg, CM; Pogorelov, VM; Rodriguiz, RM; Huang, XP; Zhu, H; McCorvy, JD; Wetsel, WC; Roth, BL; Kozikowski, AP	University of Illinois at Chicago	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148852&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44346723	104037038		CHEMBL3769968				ZINC27194094	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50471115	Cl.NCC1CC1c1cc(F)c(F)cc1OCC=C	InChI=1S/C13H15F2NO.ClH/c1-2-3-17-13-6-12(15)11(14)5-10(13)9-4-8(9)7-16;/h2,5-6,8-9H,1,3-4,7,16H2;1H	XGCOQOYOBQPELW-UHFFFAOYSA-N	50148852	CHEMBL3769968	Alpha-2A adrenergic receptor		 165								ChEMBL	10.1021/acs.jmedchem.5b01153	10.7270/Q28C9Z4P	26704965			Cheng, J; Giguere, PM; Schmerberg, CM; Pogorelov, VM; Rodriguiz, RM; Huang, XP; Zhu, H; McCorvy, JD; Wetsel, WC; Roth, BL; Kozikowski, AP	University of Illinois at Chicago	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148852&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44346723	104037038		CHEMBL3769968				ZINC27194094	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564019	Ic1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10IN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	YYTGOWDNUUXBGS-UHFFFAOYSA-N	50213347	CHEMBL70676	Alpha-2A adrenergic receptor					 11					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10382537	376070927		CHEMBL70676					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564022	C1CN=C(Nc2ccc3nccnc3c2)N1	InChI=1S/C11H11N5/c1-2-9-10(13-4-3-12-9)7-8(1)16-11-14-5-6-15-11/h1-4,7H,5-6H2,(H2,14,15,16)	PVKUNRLEOHFACD-UHFFFAOYSA-N	50213029	CHEMBL49395	Alpha-2A adrenergic receptor		 309								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213029	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213029&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10198248	376070774		CHEMBL49395					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564025	Cc1c(ccc2nccnc12)N=C1NCCN1	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)	QZUXRMOPAGPTIY-UHFFFAOYSA-N	50052880	CHEMBL49137::Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine	Alpha-2A adrenergic receptor		 7.2								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052880&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185076	103949620		CHEMBL49137				ZINC05159693	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564026	Cc1c(ccc2nccnc12)N=C1NCCN1	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)	QZUXRMOPAGPTIY-UHFFFAOYSA-N	50052880	CHEMBL49137::Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine	Alpha-2A adrenergic receptor					 1.2					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052880&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185076	103949620		CHEMBL49137				ZINC05159693	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564030	CC1CN=C(Nc2ccc3nccnc3c2Br)N1	InChI=1S/C12H12BrN5/c1-7-6-16-12(17-7)18-8-2-3-9-11(10(8)13)15-5-4-14-9/h2-5,7H,6H2,1H3,(H2,16,17,18)	XBTUHMKOYJCXOJ-UHFFFAOYSA-N	50213345	CHEMBL72995	Alpha-2A adrenergic receptor		 3802								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213345&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44312036	376070925		CHEMBL72995					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50504068	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2A adrenergic receptor		 1.7								ChEMBL	10.1021/np50094a001	10.7270/Q2VT1S4B	8496700			Sweetnam, PM; Caldwell, L; Lancaster, J; Jr., CB; McMillan, B; Kinnier, WJ; Price, CH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501039	CC(C)Cn1c(C)cc(NCc2ccc(cc2)C(F)(F)F)cc1=O	InChI=1S/C18H21F3N2O/c1-12(2)11-23-13(3)8-16(9-17(23)24)22-10-14-4-6-15(7-5-14)18(19,20)21/h4-9,12,22H,10-11H2,1-3H3	DQGLCUVKAXPIQI-UHFFFAOYSA-N	50179382	CHEMBL3814535	Alpha-2A adrenergic receptor		 58000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179382&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127048642	346549557		CHEMBL3814535					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501040	CCCCCNc1cc(C)n(CCCCC)c(=O)c1	InChI=1S/C16H28N2O/c1-4-6-8-10-17-15-12-14(3)18(16(19)13-15)11-9-7-5-2/h12-13,17H,4-11H2,1-3H3	DEWIQAQXNMTVRW-UHFFFAOYSA-N	50179383	CHEMBL3814593	Alpha-2A adrenergic receptor		 62000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179383&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127048643	346549558		CHEMBL3814593					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501041	CCCCCn1c(C)cc(NCc2ccccc2)cc1=O	InChI=1S/C18H24N2O/c1-3-4-8-11-20-15(2)12-17(13-18(20)21)19-14-16-9-6-5-7-10-16/h5-7,9-10,12-13,19H,3-4,8,11,14H2,1-2H3	XCEYUKNURZMKTA-UHFFFAOYSA-N	50179384	CHEMBL3814220	Alpha-2A adrenergic receptor		 41000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179384&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127050224	346549559		CHEMBL3814220					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501042	CCCCCn1c(C)cc(NCc2ccc(Cl)cc2)cc1=O	InChI=1S/C18H23ClN2O/c1-3-4-5-10-21-14(2)11-17(12-18(21)22)20-13-15-6-8-16(19)9-7-15/h6-9,11-12,20H,3-5,10,13H2,1-2H3	NTQIJMLBZYTGFD-UHFFFAOYSA-N	50179385	CHEMBL3814521	Alpha-2A adrenergic receptor		 80000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179385&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127048644	346549560		CHEMBL3814521					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501043	CC(C)CCNc1cc(C)n(CCC(C)C)c(=O)c1	InChI=1S/C16H28N2O/c1-12(2)6-8-17-15-10-14(5)18(16(19)11-15)9-7-13(3)4/h10-13,17H,6-9H2,1-5H3	CRGJBALPHNUUGR-UHFFFAOYSA-N	50179386	CHEMBL3814626	Alpha-2A adrenergic receptor		 52000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179386&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127048645	346549561		CHEMBL3814626					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501044	CC(C)CCn1c(C)cc(NCc2ccccc2)cc1=O	InChI=1S/C18H24N2O/c1-14(2)9-10-20-15(3)11-17(12-18(20)21)19-13-16-7-5-4-6-8-16/h4-8,11-12,14,19H,9-10,13H2,1-3H3	MNLSJZMBJWNZMG-UHFFFAOYSA-N	50179387	CHEMBL3814276	Alpha-2A adrenergic receptor		 27000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179387&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127048646	346549562		CHEMBL3814276					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501045	CC(C)CCn1c(C)cc(NCc2ccc(Cl)cc2)cc1=O	InChI=1S/C18H23ClN2O/c1-13(2)8-9-21-14(3)10-17(11-18(21)22)20-12-15-4-6-16(19)7-5-15/h4-7,10-11,13,20H,8-9,12H2,1-3H3	RRNUULLTIVWPRD-UHFFFAOYSA-N	50179388	CHEMBL3814259	Alpha-2A adrenergic receptor		 99000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179388&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127051133	346549563		CHEMBL3814259					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501046	CCCCCNc1cc(C)n(Cc2ccccc2)c(=O)c1	InChI=1S/C18H24N2O/c1-3-4-8-11-19-17-12-15(2)20(18(21)13-17)14-16-9-6-5-7-10-16/h5-7,9-10,12-13,19H,3-4,8,11,14H2,1-2H3	ZFSUQGBGJLVODB-UHFFFAOYSA-N	50179389	CHEMBL3813724	Alpha-2A adrenergic receptor		 110000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179389&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127052992	346549564		CHEMBL3813724					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501047	CC(C)CCNc1cc(C)n(Cc2ccccc2)c(=O)c1	InChI=1S/C18H24N2O/c1-14(2)9-10-19-17-11-15(3)20(18(21)12-17)13-16-7-5-4-6-8-16/h4-8,11-12,14,19H,9-10,13H2,1-3H3	IQBWQUVEORWKAE-UHFFFAOYSA-N	50179390	CHEMBL3815157	Alpha-2A adrenergic receptor		 110000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179390&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127050218	346549565		CHEMBL3815157					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501048	CN1CCCCC1CCn1c2ccccc2c2ccccc12	InChI=1S/C20H24N2/c1-21-14-7-6-8-16(21)13-15-22-19-11-4-2-9-17(19)18-10-3-5-12-20(18)22/h2-5,9-12,16H,6-8,13-15H2,1H3	ORAYTTMGMKZGDM-UHFFFAOYSA-N	50179391	CHEMBL3593723	Alpha-2A adrenergic receptor		 1200								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179391&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			43405	346549566		CHEMBL3593723					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501049	CN1CCCCC1CCn1cnc2ccccc12	InChI=1S/C15H21N3/c1-17-10-5-4-6-13(17)9-11-18-12-16-14-7-2-3-8-15(14)18/h2-3,7-8,12-13H,4-6,9-11H2,1H3	XRSDXBYSJFQJIG-UHFFFAOYSA-N	50179392	CHEMBL3593725	Alpha-2A adrenergic receptor		 11000								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179392&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			103616908	346549567		CHEMBL3593725					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501050	CNC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1	UCTWMZQNUQWSLP-VIFPVBQESA-N	50029050	(-)-(R)-epinephrine::(-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol::(-)-adrenaline::(R)-(-)-adrenaline::(R)-adrenaline::4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol::Adrenalin::CHEMBL679::EPINEPHRINE::adrenaline::levoepinephrine	Alpha-2A adrenergic receptor		 160								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029050&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	ALE	7BTS,4A7U,7BRN,2HKK,4LDO	5816	103938164	28918	CHEMBL679	DB00668	479	C02012	ZINC00039089	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501051	C1CC1C(NC1=NCCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)	CQXADFVORZEARL-UHFFFAOYSA-N	50070328	CHEBI:8862::Rilmenidine	Alpha-2A adrenergic receptor		 300								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070328&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68712	313072381					C11120		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501052	CCC1(Cc2ccccc2O1)C1=NCCN1	InChI=1S/C13H16N2O/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13/h3-6H,2,7-9H2,1H3,(H,14,15)	RATZLMXRALDSJW-UHFFFAOYSA-N	50179393	Efaroxan	Alpha-2A adrenergic receptor		 4.4								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179393&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			72016	346549568							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501053	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 28								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501054	C[C@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1	CUHVIMMYOGQXCV-NSHDSACASA-N	50085683	(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole::4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole::CHEMBL778::DEXMEDETOMIDINE::MPV 1440	Alpha-2A adrenergic receptor		 2.5								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085683&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5311068	103985093	48552	CHEMBL778				ZINC04632106	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501055	CCC1(Cc2ccccc2C1)c1cnc[nH]1	InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)	HSWPZIDYAHLZDD-UHFFFAOYSA-N	81807	ATIPAMEZOLE::CAS_104054-27-5::NSC_71310	Alpha-2A adrenergic receptor		 1.2								ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81807&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71310	131342381						ZINC05424171	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501056	CNC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1	UCTWMZQNUQWSLP-VIFPVBQESA-N	50029050	(-)-(R)-epinephrine::(-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol::(-)-adrenaline::(R)-(-)-adrenaline::(R)-adrenaline::4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol::Adrenalin::CHEMBL679::EPINEPHRINE::adrenaline::levoepinephrine	Alpha-2A adrenergic receptor					 30					ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029050&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	ALE	7BTS,4A7U,7BRN,2HKK,4LDO	5816	103938164	28918	CHEMBL679	DB00668	479	C02012	ZINC00039089	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501057	C1CC1C(NC1=NCCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)	CQXADFVORZEARL-UHFFFAOYSA-N	50070328	CHEBI:8862::Rilmenidine	Alpha-2A adrenergic receptor					 178					ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070328&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68712	313072381					C11120		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501058	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor					 30					ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50501059	C[C@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1	CUHVIMMYOGQXCV-NSHDSACASA-N	50085683	(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole::4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole::CHEMBL778::DEXMEDETOMIDINE::MPV 1440	Alpha-2A adrenergic receptor					 2.1					ChEMBL	10.1016/j.bmc.2016.05.043	10.7270/Q2NZ89J3	27265687			Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085683&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5311068	103985093	48552	CHEMBL778				ZINC04632106	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50505459	O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cnc2ccccc2n1	InChI=1S/C25H23N7OS/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31/h1-8,13,15-16,26H,9-12,14H2,(H,29,33)	IASPBORHOMBZMY-UHFFFAOYSA-N	50228363	CHEMBL257991::N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide::SRT-1720	Alpha-2A adrenergic receptor			 2830							ChEMBL	10.1021/jm8012954	10.7270/Q2ZC82V5	19199480			Vu, CB; Bemis, JE; Disch, JS; Ng, PY; Nunes, JJ; Milne, JC; Carney, DP; Lynch, AV; Smith, JJ; Lavu, S; Lambert, PD; Gagne, DJ; Jirousek, MR; Schenk, S; Olefsky, JM; Perni, RB	Sirtris Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50228363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50228363&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SR7	4BN5	24180125	104097840		CHEMBL257991				ZINC29043612	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50532147	CCN(CC)C(=O)[C@H]1CN[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34	InChI=1S/C19H23N3O/c1-3-22(4-2)19(23)13-8-15-14-6-5-7-16-18(14)12(10-20-16)9-17(15)21-11-13/h5-8,10,13,17,20-21H,3-4,9,11H2,1-2H3/t13-,17-/m1/s1	SUXLVXOMPKZBOV-CXAGYDPISA-N	50299166	(6aR,9R)-N,N-diethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide::4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide::CHEMBL21343	Alpha-2A adrenergic receptor			>10000							ChEMBL	10.1016/j.bmcl.2009.09.002	10.7270/Q2VX0GJN	19783143			Thoma, G; Baenteli, R; Lewis, I; Wagner, T; Oberer, L; Blum, W; Glickman, F; Streiff, MB; Zerwes, HG	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299166&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			169713	104140695		CHEMBL21343				ZINC05845906	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50532149	CCN(CC)C(=O)[C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)Nc1ccccc1	InChI=1S/C26H28N4O2/c1-3-29(4-2)25(31)18-13-21-20-11-8-12-22-24(20)17(15-27-22)14-23(21)30(16-18)26(32)28-19-9-6-5-7-10-19/h5-13,15,18,23,27H,3-4,14,16H2,1-2H3,(H,28,32)/t18-,23-/m1/s1	QIPWTYSOANVUKJ-WZONZLPQSA-N	50299165	(6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide::CHEMBL584554	Alpha-2A adrenergic receptor			 1930							ChEMBL	10.1016/j.bmcl.2009.09.002	10.7270/Q2VX0GJN	19783143			Thoma, G; Baenteli, R; Lewis, I; Wagner, T; Oberer, L; Blum, W; Glickman, F; Streiff, MB; Zerwes, HG	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299165&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45482789	104140694		CHEMBL584554				ZINC34837617	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539982	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(F)c(F)c2)nc2ccccc12	InChI=1S/C23H25F2N5O/c1-30(2)21-17-5-3-4-6-20(17)28-23(29-21)27-16-10-8-15(9-11-16)26-22(31)14-7-12-18(24)19(25)13-14/h3-7,12-13,15-16H,8-11H2,1-2H3,(H,26,31)(H,27,28,29)/t15-,16+	FAIMGWSOSCFGRU-IYBDPMFKSA-N	50170191	CHEMBL182150::N-((cis)-4-(4-(dimethylamino)quinazolin-2-ylamino)cyclohexyl)-3,4-difluorobenzamide::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-3,4-difluoro-benzamide	Alpha-2A adrenergic receptor			 104							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170191&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9934033	104056633		CHEMBL182150		1305		ZINC03961870	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539983	CN(C)c1cc(C)nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(Cl)cc2)n1	InChI=1S/C20H26ClN5O/c1-13-12-18(26(2)3)25-20(22-13)24-17-10-8-16(9-11-17)23-19(27)14-4-6-15(21)7-5-14/h4-7,12,16-17H,8-11H2,1-3H3,(H,23,27)(H,22,24,25)/t16-,17+	JCSAJCBJJWFNIO-CALCHBBNSA-N	50302547	4-chloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-ylamino)cyclohexyl)benzamide::CHEMBL567791	Alpha-2A adrenergic receptor			 730							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302547&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23027245	104156908		CHEMBL567791				ZINC45255257	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539984	CN(C)c1cc(C)nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(Cl)c(Cl)c2)n1	InChI=1S/C20H25Cl2N5O/c1-12-10-18(27(2)3)26-20(23-12)25-15-7-5-14(6-8-15)24-19(28)13-4-9-16(21)17(22)11-13/h4,9-11,14-15H,5-8H2,1-3H3,(H,24,28)(H,23,25,26)/t14-,15+	HZPGVFKYDDQWIZ-GASCZTMLSA-N	50302553	3,4-dichloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-ylamino)cyclohexyl)benzamide::CHEMBL568400	Alpha-2A adrenergic receptor			 130							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302553&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23027211	104156914		CHEMBL568400				ZINC45258521	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539985	CN(C)c1cc(C)nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)n1	InChI=1S/C22H25F6N5O/c1-12-8-18(33(2)3)32-20(29-12)31-17-6-4-16(5-7-17)30-19(34)13-9-14(21(23,24)25)11-15(10-13)22(26,27)28/h8-11,16-17H,4-7H2,1-3H3,(H,30,34)(H,29,31,32)/t16-,17+	YHSRTUXPXLVIAG-CALCHBBNSA-N	50302554	CHEMBL583014::N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-ylamino)cyclohexyl)-3,5-bis(trifluoromethyl)benzamide	Alpha-2A adrenergic receptor			 200							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302554&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45485061	104156915		CHEMBL583014				ZINC45315123	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539986	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(C)c2)ncc1C	InChI=1S/C21H29N5O/c1-14-6-5-7-16(12-14)20(27)23-17-8-10-18(11-9-17)24-21-22-13-15(2)19(25-21)26(3)4/h5-7,12-13,17-18H,8-11H2,1-4H3,(H,23,27)(H,22,24,25)/t17-,18+	AIMNRLCNWYRUPJ-HDICACEKSA-N	50302555	CHEMBL567993::N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)-3-methylbenzamide	Alpha-2A adrenergic receptor			 580							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302555&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45485062	104156916		CHEMBL567993				ZINC45261624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539987	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(C)cc2)ncc1C	InChI=1S/C21H29N5O/c1-14-5-7-16(8-6-14)20(27)23-17-9-11-18(12-10-17)24-21-22-13-15(2)19(25-21)26(3)4/h5-8,13,17-18H,9-12H2,1-4H3,(H,23,27)(H,22,24,25)/t17-,18+	NDWXGJDJKXDMOV-HDICACEKSA-N	50302556	CHEMBL578170::N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)-4-methylbenzamide	Alpha-2A adrenergic receptor			 1770							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302556&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23027035	104156917		CHEMBL578170				ZINC45300980	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539988	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(F)cc2)ncc1C	InChI=1S/C20H26FN5O/c1-13-12-22-20(25-18(13)26(2)3)24-17-10-8-16(9-11-17)23-19(27)14-4-6-15(21)7-5-14/h4-7,12,16-17H,8-11H2,1-3H3,(H,23,27)(H,22,24,25)/t16-,17+	BAZQBEOFVYAFHT-CALCHBBNSA-N	50302557	CHEMBL565551::N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)-4-fluorobenzamide	Alpha-2A adrenergic receptor			 470							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302557&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23027527	104156918		CHEMBL565551				ZINC45244940	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539989	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(Cl)cc2)ncc1C	InChI=1S/C20H26ClN5O/c1-13-12-22-20(25-18(13)26(2)3)24-17-10-8-16(9-11-17)23-19(27)14-4-6-15(21)7-5-14/h4-7,12,16-17H,8-11H2,1-3H3,(H,23,27)(H,22,24,25)/t16-,17+	XEOSDWIUBUJPES-CALCHBBNSA-N	50302558	4-chloro-N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)benzamide::CHEMBL577912	Alpha-2A adrenergic receptor			 1590							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302558&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23027411	104156919		CHEMBL577912				ZINC45298425	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539990	CN(C)c1nc(N[C@@H]2CC[C@H](CNC(=O)c3ccc(F)c(F)c3)CC2)ncc1C	InChI=1S/C21H27F2N5O/c1-13-11-25-21(27-19(13)28(2)3)26-16-7-4-14(5-8-16)12-24-20(29)15-6-9-17(22)18(23)10-15/h6,9-11,14,16H,4-5,7-8,12H2,1-3H3,(H,24,29)(H,25,26,27)/t14-,16+	NFQWOMAFZMZYOX-FZNQNYSPSA-N	50302564	CHEMBL577904::N-(((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)methyl)-3,4-difluorobenzamide	Alpha-2A adrenergic receptor			 210							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302564&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45484995	104156925		CHEMBL577904				ZINC45290649	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50539991	CN(C)c1nc(N[C@@H]2CC[C@H](CNC(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)CC2)ncc1C	InChI=1S/C23H27F6N5O/c1-13-11-31-21(33-19(13)34(2)3)32-18-6-4-14(5-7-18)12-30-20(35)15-8-16(22(24,25)26)10-17(9-15)23(27,28)29/h8-11,14,18H,4-7,12H2,1-3H3,(H,30,35)(H,31,32,33)/t14-,18+	OOUPDYBXVFKJRL-UJKQEGAGSA-N	50302568	CHEMBL566075::N-[(cis-4-{[4-(Dimethylamino)-5-methylpyrimidin-2-yl]amino}cyclohexyl)methyl]-3,5-bis(trifluoromethyl)benzamide	Alpha-2A adrenergic receptor			 310							ChEMBL	10.1016/j.bmcl.2009.09.003	10.7270/Q2KK9BVH	19773162			Semple, G; Tran, TA; Kramer, B; Hsu, D; Han, S; Choi, J; Vallar, P; Casper, MD; Zou, N; Hauser, EK; Thomsen, W; Whelan, K; Sengupta, D; Morgan, M; Sekiguchi, Y; Kanuma, K; Chaki, S; Grottick, AJ	Arena Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			15987265	104156929		CHEMBL566075				ZINC34853831	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50544101	CN(C)Cc1nc(-c2ccc(cc2)C(C)(C)C)n(n1)-c1cccc(O)c1	InChI=1S/C21H26N4O/c1-21(2,3)16-11-9-15(10-12-16)20-22-19(14-24(4)5)23-25(20)17-7-6-8-18(26)13-17/h6-13,26H,14H2,1-5H3	ILPANLYEJQKXKY-UHFFFAOYSA-N	50304075	3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl)-1H-1,2,4-triazol-1-yl)phenol::CHEMBL595449	Alpha-2A adrenergic receptor			>10000							ChEMBL	10.1016/j.bmc.2009.07.007	10.7270/Q2QZ2B14	19646882			Peng, Y; Zhang, Q; Arora, S; Keenan, SM; Kortagere, S; Wannemacher, KM; Howells, RD; Welsh, WJ	University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School and the Informatics Institute of UMDNJ	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304075	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304075&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11957735	104158436		CHEMBL595449				ZINC45350099	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50532262	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50203564	(1R,2S,4aR,13bS,14aS)-2-hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester hydrochloride::CHEMBL537669::Yohimbine Hydrochloride::cid_6169	Alpha-2A adrenergic receptor			 3.67							ChEMBL	10.1021/jm900458r	10.7270/Q2MG7PJ4	19788200			Biancalani, C; Giovannoni, MP; Pieretti, S; Cesari, N; Graziano, A; Vergelli, C; Cilibrizzi, A; Di Gianuario, A; Colucci, M; Mangano, G; Garrone, B; Polenzani, L; Dal Piaz, V	Dipartimento di Scienze Farmaceutiche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203564&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438146	104082645		CHEMBL537669	DB01392		C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50532266	Cc1ccc(cc1)N1CCN(CCCn2nc(C)c(C=C)c(N)c2=O)CC1	InChI=1S/C21H29N5O/c1-4-19-17(3)23-26(21(27)20(19)22)11-5-10-24-12-14-25(15-13-24)18-8-6-16(2)7-9-18/h4,6-9H,1,5,10-15,22H2,2-3H3	SSHKNPUBWWFZGC-UHFFFAOYSA-N	50299208	4-amino-6-methyl-2-(3-(4-p-tolylpiperazin-1-yl)propyl)-5-vinylpyridazin-3(2H)-one::CHEMBL584606	Alpha-2A adrenergic receptor			 320							ChEMBL	10.1021/jm900458r	10.7270/Q2MG7PJ4	19788200			Biancalani, C; Giovannoni, MP; Pieretti, S; Cesari, N; Graziano, A; Vergelli, C; Cilibrizzi, A; Di Gianuario, A; Colucci, M; Mangano, G; Garrone, B; Polenzani, L; Dal Piaz, V	Dipartimento di Scienze Farmaceutiche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299208&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44596863	104140737		CHEMBL584606				ZINC45319048	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50553190	N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12	InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	OPTAOWZLDMSBKX-OAHLLOKOSA-N	50308182	(3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyrrolidin-3-amine::CHEMBL604102	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm901674f	10.7270/Q22B8Z43	20170099			Haydar, SN; Yun, H; Andrae, PM; Mattes, J; Zhang, J; Kramer, A; Smith, DL; Huselton, C; Graf, R; Aschmies, S; Schechter, LE; Comery, TA; Robichaud, AJ	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50308182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50308182&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25067564	104162543		CHEMBL604102				ZINC43207081	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563710	O=C(N1CCN(CC1)C(=O)c1ccc2cc[nH]c2c1)c1ccc(cc1)-c1ccccc1	InChI=1S/C26H23N3O2/c30-25(22-9-6-20(7-10-22)19-4-2-1-3-5-19)28-14-16-29(17-15-28)26(31)23-11-8-21-12-13-27-24(21)18-23/h1-13,18,27H,14-17H2	APHXKHUFVKITGC-UHFFFAOYSA-N	50312770	(4-(1H-indole-6-carbonyl)piperazin-1-yl)(biphenyl-4-yl)methanone::CHEMBL1076586	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312770&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3676358	104147131		CHEMBL1076586				ZINC01501732	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563711	COc1cccc(c1)-c1ccc(cc1)C(=O)N1CCN([C@@H](C)C1)C(=O)c1ccc2cc[nH]c2c1	InChI=1S/C28H27N3O3/c1-19-18-30(14-15-31(19)28(33)24-11-8-21-12-13-29-26(21)17-24)27(32)22-9-6-20(7-10-22)23-4-3-5-25(16-23)34-2/h3-13,16-17,19,29H,14-15,18H2,1-2H3/t19-/m0/s1	YNLYAYGRKYOTBJ-IBGZPJMESA-N	50312771	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(3'-methoxybiphenyl-4-yl)methanone::CHEMBL1081648	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312771	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312771&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880462	104147132		CHEMBL1081648				ZINC49036016	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563712	COc1cccc(c1)-c1ccc(cc1)C(=O)N1CCN([C@H](C)C1)C(=O)c1ccc2cc[nH]c2c1	InChI=1S/C28H27N3O3/c1-19-18-30(14-15-31(19)28(33)24-11-8-21-12-13-29-26(21)17-24)27(32)22-9-6-20(7-10-22)23-4-3-5-25(16-23)34-2/h3-13,16-17,19,29H,14-15,18H2,1-2H3/t19-/m1/s1	YNLYAYGRKYOTBJ-LJQANCHMSA-N	50312772	(R)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(3'-methoxybiphenyl-4-yl)methanone::CHEMBL1081649	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312772&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880463	104147133		CHEMBL1081649				ZINC49109322	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563713	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1cccc(OC(F)(F)F)c1	InChI=1S/C28H24F3N3O3/c1-18-17-33(13-14-34(18)27(36)23-10-7-20-11-12-32-25(20)16-23)26(35)21-8-5-19(6-9-21)22-3-2-4-24(15-22)37-28(29,30)31/h2-12,15-16,18,32H,13-14,17H2,1H3/t18-/m0/s1	UPQNBHKMICCAIA-SFHVURJKSA-N	50312773	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(3'-(trifluoromethoxy)biphenyl-4-yl)methanone::CHEMBL1080155	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312773&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880498	104147134		CHEMBL1080155				ZINC49785377	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563714	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1cccc(c1)C(F)(F)F	InChI=1S/C28H24F3N3O2/c1-18-17-33(13-14-34(18)27(36)23-10-7-20-11-12-32-25(20)16-23)26(35)21-8-5-19(6-9-21)22-3-2-4-24(15-22)28(29,30)31/h2-12,15-16,18,32H,13-14,17H2,1H3/t18-/m0/s1	MYYHPWVXRPLYMD-SFHVURJKSA-N	50312774	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(3'-(trifluoromethyl)biphenyl-4-yl)methanone::CHEMBL1082209	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312774&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880566	104147135		CHEMBL1082209				ZINC49110501	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563715	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1cccc(F)c1	InChI=1S/C27H24FN3O2/c1-18-17-30(13-14-31(18)27(33)23-10-7-20-11-12-29-25(20)16-23)26(32)21-8-5-19(6-9-21)22-3-2-4-24(28)15-22/h2-12,15-16,18,29H,13-14,17H2,1H3/t18-/m0/s1	LGKIWGDJKNJYMG-SFHVURJKSA-N	50312775	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(3'-fluorobiphenyl-4-yl)methanone::CHEMBL1082210	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312775	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312775&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880567	104147136		CHEMBL1082210				ZINC49035773	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563716	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1ccccc1	InChI=1S/C27H25N3O2/c1-19-18-29(26(31)23-10-7-21(8-11-23)20-5-3-2-4-6-20)15-16-30(19)27(32)24-12-9-22-13-14-28-25(22)17-24/h2-14,17,19,28H,15-16,18H2,1H3/t19-/m0/s1	GGUUYQBMWBFCFQ-IBGZPJMESA-N	50312776	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(biphenyl-4-yl)methanone::CHEMBL1082211	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312776&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880568	104147137		CHEMBL1082211				ZINC49035775	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563717	COc1ccccc1-c1ccc(cc1)C(=O)N1CCN([C@@H](C)C1)C(=O)c1ccc2cc[nH]c2c1	InChI=1S/C28H27N3O3/c1-19-18-30(15-16-31(19)28(33)23-12-9-21-13-14-29-25(21)17-23)27(32)22-10-7-20(8-11-22)24-5-3-4-6-26(24)34-2/h3-14,17,19,29H,15-16,18H2,1-2H3/t19-/m0/s1	WGTCBXOFOSMWEQ-IBGZPJMESA-N	50312777	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2'-methoxybiphenyl-4-yl)methanone::CHEMBL1081212	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312777	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312777&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880569	104147138		CHEMBL1081212				ZINC49034033	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563718	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1ccccc1F	InChI=1S/C27H24FN3O2/c1-18-17-30(14-15-31(18)27(33)22-11-8-20-12-13-29-25(20)16-22)26(32)21-9-6-19(7-10-21)23-4-2-3-5-24(23)28/h2-13,16,18,29H,14-15,17H2,1H3/t18-/m0/s1	MESZSUFNQDICOD-SFHVURJKSA-N	50312778	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2'-fluorobiphenyl-4-yl)methanone::CHEMBL1080389	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312778&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880628	104147139		CHEMBL1080389				ZINC49033744	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563719	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1ccccc1Cl	InChI=1S/C27H24ClN3O2/c1-18-17-30(14-15-31(18)27(33)22-11-8-20-12-13-29-25(20)16-22)26(32)21-9-6-19(7-10-21)23-4-2-3-5-24(23)28/h2-13,16,18,29H,14-15,17H2,1H3/t18-/m0/s1	ZMAZHOAGBMLOSO-SFHVURJKSA-N	50312779	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2'-chlorobiphenyl-4-yl)methanone::CHEMBL1080556	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312779&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880629	104147140		CHEMBL1080556				ZINC49032986	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563720	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1ccccc1C(F)(F)F	InChI=1S/C28H24F3N3O2/c1-18-17-33(14-15-34(18)27(36)22-11-8-20-12-13-32-25(20)16-22)26(35)21-9-6-19(7-10-21)23-4-2-3-5-24(23)28(29,30)31/h2-13,16,18,32H,14-15,17H2,1H3/t18-/m0/s1	CZUGKEKGXKWONC-SFHVURJKSA-N	50312780	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2'-(trifluoromethyl)biphenyl-4-yl)methanone::CHEMBL1080735	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312780&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880630	104147141		CHEMBL1080735				ZINC49785313	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563721	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1ccccc1C	InChI=1S/C28H27N3O2/c1-19-5-3-4-6-25(19)21-7-10-23(11-8-21)27(32)30-15-16-31(20(2)18-30)28(33)24-12-9-22-13-14-29-26(22)17-24/h3-14,17,20,29H,15-16,18H2,1-2H3/t20-/m0/s1	LADSERODBYZUAW-FQEVSTJZSA-N	50312766	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2'-methylbiphenyl-4-yl)methanone::CHEMBL1080907	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312766	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312766&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880631	104147127		CHEMBL1080907				ZINC49033879	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563722	COc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCN([C@@H](C)C1)C(=O)c1ccc2cc[nH]c2c1	InChI=1S/C28H27N3O3/c1-19-18-30(15-16-31(19)28(33)24-8-5-22-13-14-29-26(22)17-24)27(32)23-6-3-20(4-7-23)21-9-11-25(34-2)12-10-21/h3-14,17,19,29H,15-16,18H2,1-2H3/t19-/m0/s1	ZALZZXXESRJJEH-IBGZPJMESA-N	50312767	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(4'-methoxybiphenyl-4-yl)methanone::CHEMBL1081254	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312767	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312767&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880672	104147128		CHEMBL1081254				ZINC49785142	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563723	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1ccc(OC(F)(F)F)cc1	InChI=1S/C28H24F3N3O3/c1-18-17-33(14-15-34(18)27(36)23-7-4-21-12-13-32-25(21)16-23)26(35)22-5-2-19(3-6-22)20-8-10-24(11-9-20)37-28(29,30)31/h2-13,16,18,32H,14-15,17H2,1H3/t18-/m0/s1	MIJPHKXHAZCAQK-SFHVURJKSA-N	50312768	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(4'-(trifluoromethoxy)biphenyl-4-yl)methanone::CHEMBL1080755	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312768	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312768&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880673	104147129		CHEMBL1080755				ZINC49785479	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563724	C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1ccc(F)cc1	InChI=1S/C27H24FN3O2/c1-18-17-30(14-15-31(18)27(33)23-7-4-21-12-13-29-25(21)16-23)26(32)22-5-2-19(3-6-22)20-8-10-24(28)11-9-20/h2-13,16,18,29H,14-15,17H2,1H3/t18-/m0/s1	KFUNLUIORXHBPH-SFHVURJKSA-N	50312769	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(4'-fluorobiphenyl-4-yl)methanone::CHEMBL1080926	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2010.01.043	10.7270/Q2WM1DJD	20137933			Yu, M; Lizarzaburu, M; Beckmann, H; Connors, R; Dai, K; Haller, K; Li, C; Liang, L; Lindstrom, M; Ma, J; Motani, A; Wanska, M; Zhang, A; Li, L; Medina, JC	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312769	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312769&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46880674	104147130		CHEMBL1080926				ZINC49032774	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592315	COc1ccccc1N1CCN(CCNC(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C24H27N3O2/c1-29-23-9-5-4-8-22(23)27-16-14-26(15-17-27)13-12-25-24(28)21-11-10-19-6-2-3-7-20(19)18-21/h2-11,18H,12-17H2,1H3,(H,25,28)	VUQFQRNHGGYQGK-UHFFFAOYSA-N	50324887	CHEMBL1221498::N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-2-naphthamide	Alpha-2A adrenergic receptor		 1.69								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324887&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			42266865	117646208		CHEMBL1221498				ZINC56965850	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592319	COc1ccccc1N1CCN(CCNS(=O)(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C23H27N3O3S/c1-29-23-9-5-4-8-22(23)26-16-14-25(15-17-26)13-12-24-30(27,28)21-11-10-19-6-2-3-7-20(19)18-21/h2-11,18,24H,12-17H2,1H3	RQEBRILFCMJWAD-UHFFFAOYSA-N	50324888	CHEMBL1221499::N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)naphthalene-2-sulfonamide	Alpha-2A adrenergic receptor		 5.19								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			42267840	117646209		CHEMBL1221499				ZINC56966182	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592322	COc1ccccc1N1CCN(CCCNC(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C25H29N3O2/c1-30-24-10-5-4-9-23(24)28-17-15-27(16-18-28)14-6-13-26-25(29)22-12-11-20-7-2-3-8-21(20)19-22/h2-5,7-12,19H,6,13-18H2,1H3,(H,26,29)	VSRXHPMNIVBYAT-UHFFFAOYSA-N	50324889	CHEMBL1221544::N-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)-2-naphthamide	Alpha-2A adrenergic receptor		 4.59								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324889&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			42273326	117646210		CHEMBL1221544				ZINC11909404	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592325	COc1ccccc1N1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C24H29N3O3S/c1-30-24-10-5-4-9-23(24)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-12-11-20-7-2-3-8-21(20)19-22/h2-5,7-12,19,25H,6,13-18H2,1H3	YRVKJIDCHIEELY-UHFFFAOYSA-N	50261126	CHEMBL497749::N-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)naphthalene-2-sulfonamide::Naphthalene-2-sulfonic acid {3-[4-(2-methoxyphenyl)-piperazin-1-yl]-propyl}-amide	Alpha-2A adrenergic receptor		 4.64								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261126&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			42388639	104110369		CHEMBL497749				ZINC12068667	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592329	COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C26H31N3O2/c1-31-25-11-5-4-10-24(25)29-18-16-28(17-19-29)15-7-6-14-27-26(30)23-13-12-21-8-2-3-9-22(21)20-23/h2-5,8-13,20H,6-7,14-19H2,1H3,(H,27,30)	MNHDKMDLOJSCGN-UHFFFAOYSA-N	50119380	CHEMBL25236::CHEMBL540612::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide::Naphthalene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide	Alpha-2A adrenergic receptor		 2.75								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119380&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038495	104012598		CHEMBL25236CHEMBL540612				ZINC03917109	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592332	COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C25H31N3O3S/c1-31-25-11-5-4-10-24(25)28-18-16-27(17-19-28)15-7-6-14-26-32(29,30)23-13-12-21-8-2-3-9-22(21)20-23/h2-5,8-13,20,26H,6-7,14-19H2,1H3	AUMIZIKCBYPWJM-UHFFFAOYSA-N	50324890	CHEMBL1221545::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)naphthalene-2-sulfonamide	Alpha-2A adrenergic receptor		 4.1								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324890&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49864336	117646211		CHEMBL1221545				ZINC58590751	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592336	COc1ccccc1N1CCN(CCCCCNC(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C27H33N3O2/c1-32-26-12-6-5-11-25(26)30-19-17-29(18-20-30)16-8-2-7-15-28-27(31)24-14-13-22-9-3-4-10-23(22)21-24/h3-6,9-14,21H,2,7-8,15-20H2,1H3,(H,28,31)	WUTIBZPSZGYSGD-UHFFFAOYSA-N	50324891	CHEMBL1221591::N-(5-(4-(2-methoxyphenyl)piperazin-1-yl)pentyl)-2-naphthamide	Alpha-2A adrenergic receptor		 11.1								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324891	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324891&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46934426	117646212		CHEMBL1221591				ZINC58591673	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592340	COc1ccccc1N1CCN(CCCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C26H33N3O3S/c1-32-26-12-6-5-11-25(26)29-19-17-28(18-20-29)16-8-2-7-15-27-33(30,31)24-14-13-22-9-3-4-10-23(22)21-24/h3-6,9-14,21,27H,2,7-8,15-20H2,1H3	NADZGFHXOOQKNN-UHFFFAOYSA-N	50324892	CHEMBL1221592::N-(5-(4-(2-methoxyphenyl)piperazin-1-yl)pentyl)naphthalene-2-sulfonamide	Alpha-2A adrenergic receptor		 8.53								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324892	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324892&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49864359	117646213		CHEMBL1221592				ZINC58581231	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592344	COc1ccccc1N1CCN(CCCCCCNC(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C28H35N3O2/c1-33-27-13-7-6-12-26(27)31-20-18-30(19-21-31)17-9-3-2-8-16-29-28(32)25-15-14-23-10-4-5-11-24(23)22-25/h4-7,10-15,22H,2-3,8-9,16-21H2,1H3,(H,29,32)	GNQMAWAOPDTCCX-UHFFFAOYSA-N	50324893	CHEMBL1221593::N-(6-(4-(2-methoxyphenyl)piperazin-1-yl)hexyl)-2-naphthamide	Alpha-2A adrenergic receptor		 6.15								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324893	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324893&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49864360	117646214		CHEMBL1221593				ZINC58584091	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50592348	COc1ccccc1N1CCN(CCCCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1	InChI=1S/C27H35N3O3S/c1-33-27-13-7-6-12-26(27)30-20-18-29(19-21-30)17-9-3-2-8-16-28-34(31,32)25-15-14-23-10-4-5-11-24(23)22-25/h4-7,10-15,22,28H,2-3,8-9,16-21H2,1H3	WEXLHWFGOZCTNY-UHFFFAOYSA-N	50324894	CHEMBL1221594::N-(6-(4-(2-methoxyphenyl)piperazin-1-yl)hexyl)naphthalene-2-sulfonamide	Alpha-2A adrenergic receptor		 2.87								ChEMBL	10.1016/j.bmcl.2010.07.002	10.7270/Q2445MPJ	20656482			Resimont, M; Liegeois, JF	University of Li&#232;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324894	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324894&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46934427	117646215		CHEMBL1221594				ZINC58584093	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50594071	Oc1ccc2[C@@H]3CNCC[C@H]3[C@@H](Cc2c1O)c1ccccc1	InChI=1S/C19H21NO2/c21-18-7-6-13-16(19(18)22)10-15(12-4-2-1-3-5-12)14-8-9-20-11-17(13)14/h1-7,14-15,17,20-22H,8-11H2/t14-,15-,17-/m0/s1	FKYWSGYMKJUZEP-ZOBUZTSGSA-N	50325822	CHEMBL1224527::trans-(5R)-5-phenyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[h]isoquinoline-7,8-diol	Alpha-2A adrenergic receptor		 3500								ChEMBL	10.1016/j.bmc.2010.07.052	10.7270/Q29K4BFR	20709559			Bonner, LA; Chemel, BR; Watts, VJ; Nichols, DE	Purdue University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325822&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46869265	117647143		CHEMBL1224527				ZINC58581107	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50580089	Fc1ccc(cc1)-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1	InChI=1S/C21H27FN4O/c22-18-8-6-17(7-9-18)20-11-10-19(16-24-20)25-21(27)23-12-2-5-15-26-13-3-1-4-14-26/h6-11,16H,1-5,12-15H2,(H2,23,25,27)	LMGUUVWYFJIKCD-UHFFFAOYSA-N	50319673	1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl)urea::CHEMBL1083787	Alpha-2A adrenergic receptor			 35000							ChEMBL	10.1021/jm901692q	10.7270/Q2S46S4Q	20465311			Ghiron, C; Haydar, SN; Aschmies, S; Bothmann, H; Castaldo, C; Cocconcelli, G; Comery, TA; Di, L; Dunlop, J; Lock, T; Kramer, A; Kowal, D; Jow, F; Grauer, S; Harrison, B; La Rosa, S; Maccari, L; Marquis, KL; Micco, I; Nencini, A; Quinn, J; Robichaud, AJ; Roncarati, R; Scali, C; Terstappen, GC; Turlizzi, E; Valacchi, M; Varrone, M; Zanaletti, R; Zanelli, U	Siena Biotech SpA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319673&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44240743	104154034		CHEMBL1083787				ZINC49035878	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50598629	C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21	InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1	CKLPLPZSUQEDRT-WPCRTTGESA-N	50318666	(1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-tetrahydrospiro-[beta-carboline-1,3'-indol]-2'(1'H)-one::CHEMBL1082723::NITD609	Alpha-2A adrenergic receptor			>10000							ChEMBL	10.1126/science.1193225	10.7270/Q2SB45ZB	20813948			Rottmann, M; McNamara, C; Yeung, BK; Lee, MC; Zou, B; Russell, B; Seitz, P; Plouffe, DM; Dharia, NV; Tan, J; Cohen, SB; Spencer, KR; Gonzalez-Paez, GE; Lakshminarayana, SB; Goh, A; Suwanarusk, R; Jegla, T; Schmitt, EK; Beck, HP; Brun, R; Nosten, F; Renia, L; Dartois, V; Keller, TH; Fidock, DA; Winzeler, EA; Diagana, TT	Swiss Tropical and Public Health Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318666&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44469321	104153027		CHEMBL1082723				ZINC49037032	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50581865	CN1CC2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C25H30N4O/c1-27-18-22-24(30-26-25(22)21-11-5-6-12-23(21)27)19-29-16-14-28(15-17-29)13-7-10-20-8-3-2-4-9-20/h2-12,22,24H,13-19H2,1H3/b10-7+/t22?,24-/m0/s1	GHPKBFZQNLPFFZ-BIGUYTSMSA-N	50320446	CHEMBL1085510::[N-methyl]5-methyl-3-[4-(3-phenylallyl)-piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroisoxazolo[4,3-c]quinoline	Alpha-2A adrenergic receptor		 1.6								ChEMBL	10.1016/j.bmcl.2010.04.099	10.7270/Q2474B1C	20529687			Prabhakaran, J; Majo, VJ; Milak, MS; Mali, P; Savenkova, L; Mann, JJ; Parsey, RV; Kumar, JS	Columbia University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320446&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46891598	104141975		CHEMBL1085510				ZINC49115356	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50601661	CCCCN1CCC(COC(=O)c2cc(Cl)c(NC)c3OCCOc23)CC1	InChI=1S/C20H29ClN2O4/c1-3-4-7-23-8-5-14(6-9-23)13-27-20(24)15-12-16(21)17(22-2)19-18(15)25-10-11-26-19/h12,14,22H,3-11,13H2,1-2H3	WKWADEWWLCVVLF-UHFFFAOYSA-N	50327860	(1-Butylpiperidin-4-yl)methyl 7-chloro-8-(methylamino)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate::CHEMBL1258223	Alpha-2A adrenergic receptor		 2239								ChEMBL	10.1021/jm100668r	10.7270/Q2BR8SD7	20812727			Xu, R; Hong, J; Morse, CL; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327860&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49783209	123106975		CHEMBL1258223				ZINC64548813	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50601702	CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1	InChI=1S/C18H28N2O3/c1-3-4-9-20-10-7-14(8-11-20)13-23-18(21)15-5-6-16(19)17(12-15)22-2/h5-6,12,14H,3-4,7-11,13,19H2,1-2H3	DZZIAERGLDKTBT-UHFFFAOYSA-N	50327861	(1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxybenzoate::CHEMBL1258452	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm100668r	10.7270/Q2BR8SD7	20812727			Xu, R; Hong, J; Morse, CL; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327861&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49783415	123106976		CHEMBL1258452				ZINC64548966	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50601711	CCCCN1CCC(COC(=O)c2cc(F)c(N)c3OCCOc23)CC1	InChI=1S/C19H27FN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	WLHFUBIRAHRPHA-UHFFFAOYSA-N	50327863	(1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate::CHEMBL1258671	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm100668r	10.7270/Q2BR8SD7	20812727			Xu, R; Hong, J; Morse, CL; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327863&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49783419	123106978		CHEMBL1258671				ZINC64548828	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50617786	O=S(=O)(c1n[nH]c2ccc(NC3CCNCC3)cc12)c1cccc2ccccc12	InChI=1S/C22H22N4O2S/c27-29(28,21-7-3-5-15-4-1-2-6-18(15)21)22-19-14-17(8-9-20(19)25-26-22)24-16-10-12-23-13-11-16/h1-9,14,16,23-24H,10-13H2,(H,25,26)	PBZTVWPXUNSZDN-UHFFFAOYSA-N	50334731	CHEMBL1642851::[3-(Naphthalen-1-sulfonyl)-1H-indazol-5-yl]-piperidin-4-yl-amine HCl	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1016/j.bmc.2010.10.033	10.7270/Q29S1R9V	21093272			Liu, KG; Robichaud, AJ; Greenfield, AA; Lo, JR; Grosanu, C; Mattes, JF; Cai, Y; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Di, L; Kerns, EH; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334731&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16118795	125084833		CHEMBL1642851				ZINC35285088	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50617787	Clc1cccc(c1)S(=O)(=O)c1n[nH]c2ccc(NC3CCNCC3)cc12	InChI=1S/C18H19ClN4O2S/c19-12-2-1-3-15(10-12)26(24,25)18-16-11-14(4-5-17(16)22-23-18)21-13-6-8-20-9-7-13/h1-5,10-11,13,20-21H,6-9H2,(H,22,23)	AEFDXRNFDYCLFW-UHFFFAOYSA-N	50334732	3-(3-Chlorophenylsulfonyl)-N-(piperidin-4-yl)-1H-indazol-5-amine HCl::CHEMBL1642882	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1016/j.bmc.2010.10.033	10.7270/Q29S1R9V	21093272			Liu, KG; Robichaud, AJ; Greenfield, AA; Lo, JR; Grosanu, C; Mattes, JF; Cai, Y; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Di, L; Kerns, EH; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334732&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16117151	125084834		CHEMBL1642882				ZINC35278957	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50617788	CC(C)c1ccc(cc1)S(=O)(=O)c1n[nH]c2ccc(NC3CCNCC3)cc12	InChI=1S/C21H26N4O2S/c1-14(2)15-3-6-18(7-4-15)28(26,27)21-19-13-17(5-8-20(19)24-25-21)23-16-9-11-22-12-10-16/h3-8,13-14,16,22-23H,9-12H2,1-2H3,(H,24,25)	JHVNSHBHMRPFIN-UHFFFAOYSA-N	50334733	3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1Hindazol-5-amine HCl::CHEMBL1642886	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1016/j.bmc.2010.10.033	10.7270/Q29S1R9V	21093272			Liu, KG; Robichaud, AJ; Greenfield, AA; Lo, JR; Grosanu, C; Mattes, JF; Cai, Y; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Di, L; Kerns, EH; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334733&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16117279	125084835		CHEMBL1642886				ZINC35279646	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50617789	O=S(=O)(c1n[nH]c2ccc(NC3CCNCC3)cc12)c1ccc2ccccc2c1	InChI=1S/C22H22N4O2S/c27-29(28,19-7-5-15-3-1-2-4-16(15)13-19)22-20-14-18(6-8-21(20)25-26-22)24-17-9-11-23-12-10-17/h1-8,13-14,17,23-24H,9-12H2,(H,25,26)	DVEBXLWTIWPHPE-UHFFFAOYSA-N	50334734	3-(Naphthalen-2-ylsulfonyl)-N-(piperidin-4-yl)-1H-indazol-5-amine HCl::CHEMBL1642889	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1016/j.bmc.2010.10.033	10.7270/Q29S1R9V	21093272			Liu, KG; Robichaud, AJ; Greenfield, AA; Lo, JR; Grosanu, C; Mattes, JF; Cai, Y; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Di, L; Kerns, EH; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334734&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16117153	125084836		CHEMBL1642889				ZINC35278970	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50617790	NCCC(=O)Nc1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12	InChI=1S/C20H18N4O3S/c21-11-10-19(25)22-14-8-9-17-16(12-14)20(24-23-17)28(26,27)18-7-3-5-13-4-1-2-6-15(13)18/h1-9,12H,10-11,21H2,(H,22,25)(H,23,24)	ZOULCJHSOKLTEE-UHFFFAOYSA-N	50334720	3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-yl]-propionamide HCl::CHEMBL1642865	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1016/j.bmc.2010.10.033	10.7270/Q29S1R9V	21093272			Liu, KG; Robichaud, AJ; Greenfield, AA; Lo, JR; Grosanu, C; Mattes, JF; Cai, Y; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Di, L; Kerns, EH; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334720&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16071847	125084822		CHEMBL1642865				ZINC35000355	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50617791	O=C(Nc1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12)C1CCNCC1	InChI=1S/C23H22N4O3S/c28-22(16-10-12-24-13-11-16)25-17-8-9-20-19(14-17)23(27-26-20)31(29,30)21-7-3-5-15-4-1-2-6-18(15)21/h1-9,14,16,24H,10-13H2,(H,25,28)(H,26,27)	QQYRQLGIRAUMJS-UHFFFAOYSA-N	50334725	CHEMBL1642866::N-(3-(Naphthalen-1-ylsulfonyl)-1H-indazol-5-yl)piperidine-4-carboxamide HCl	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1016/j.bmc.2010.10.033	10.7270/Q29S1R9V	21093272			Liu, KG; Robichaud, AJ; Greenfield, AA; Lo, JR; Grosanu, C; Mattes, JF; Cai, Y; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Di, L; Kerns, EH; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334725&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16118923	125084827		CHEMBL1642866				ZINC35285409	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616612	C1CNC(N1)=Nc1[nH]nc2ccccc12	InChI=1S/C10H11N5/c1-2-4-8-7(3-1)9(15-14-8)13-10-11-5-6-12-10/h1-4H,5-6H2,(H3,11,12,13,14,15)	HSFNBHMGHLXGGC-UHFFFAOYSA-N	50334194	3-[(Imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1641679	Alpha-2A adrenergic receptor					 82					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334194&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53322686	125084296		CHEMBL1641679				ZINC66165964	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616613	Clc1cccc2n[nH]c(N=C3NCCN3)c12	InChI=1S/C10H10ClN5/c11-6-2-1-3-7-8(6)9(16-15-7)14-10-12-4-5-13-10/h1-3H,4-5H2,(H3,12,13,14,15,16)	GZOSTMMHWPNBSI-UHFFFAOYSA-N	50334195	4-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1641681	Alpha-2A adrenergic receptor					 240					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334195&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53324490	125084297		CHEMBL1641681				ZINC66167072	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616614	Cc1cccc2n[nH]c(N=C3NCCN3)c12	InChI=1S/C11H13N5/c1-7-3-2-4-8-9(7)10(16-15-8)14-11-12-5-6-13-11/h2-4H,5-6H2,1H3,(H3,12,13,14,15,16)	BILZSFIMYIREAG-UHFFFAOYSA-N	50334196	3-[(Imidazolidin-2-yl)imino]-4-methylindazole hydrochloride::CHEMBL1641682	Alpha-2A adrenergic receptor					 14					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334196&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50994258	125084298		CHEMBL1641682				ZINC66157170	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616615	Clc1cccc2c(N=C3NCCN3)[nH]nc12	InChI=1S/C10H10ClN5/c11-7-3-1-2-6-8(7)15-16-9(6)14-10-12-4-5-13-10/h1-3H,4-5H2,(H3,12,13,14,15,16)	IVRZKTAWAHLCMO-UHFFFAOYSA-N	50334197	7-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1641689	Alpha-2A adrenergic receptor					 73					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334197&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50994260	125084299		CHEMBL1641689				ZINC66165820	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616616	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2A adrenergic receptor					 110					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616617	C[C@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1	CUHVIMMYOGQXCV-NSHDSACASA-N	50085683	(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole::4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole::CHEMBL778::DEXMEDETOMIDINE::MPV 1440	Alpha-2A adrenergic receptor					 1.5					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085683&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5311068	103985093	48552	CHEMBL778				ZINC04632106	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616618	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor					 28					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616619	C1CNC(N1)=Nn1ncc2ccccc12	InChI=1S/C10H11N5/c1-2-4-9-8(3-1)7-13-15(9)14-10-11-5-6-12-10/h1-4,7H,5-6H2,(H2,11,12,14)	PFTFJTOQCWYCNM-UHFFFAOYSA-N	50271255	1-[(Imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1186220::CHEMBL454712	Alpha-2A adrenergic receptor					 160					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271255&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24882007	104116144		CHEMBL454712CHEMBL1186220				ZINC40846960	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616620	Clc1cccc2n(N=C3NCCN3)ncc12	InChI=1S/C10H10ClN5/c11-8-2-1-3-9-7(8)6-14-16(9)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	MZZKJDOJNLLGRR-UHFFFAOYSA-N	50271294	4-Chloro-1-[(imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1186774::CHEMBL477504	Alpha-2A adrenergic receptor					 180					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271294&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24882106	104116172		CHEMBL1186774CHEMBL477504				ZINC40943702	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616621	Cc1cccc2cnn(N=C3NCCN3)c12	InChI=1S/C11H13N5/c1-8-3-2-4-9-7-14-16(10(8)9)15-11-12-5-6-13-11/h2-4,7H,5-6H2,1H3,(H2,12,13,15)	MRRLJQVNGWKPQF-UHFFFAOYSA-N	50270556	1-[(Imidazolidin-2-yl)imino]-7-methylindazole hydrochloride::CHEMBL1186788::CHEMBL478356	Alpha-2A adrenergic receptor					 37					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270556&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24882019	104115727		CHEMBL1186788CHEMBL478356				ZINC40918224	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50616622	Clc1cccc2cnn(N=C3NCCN3)c12	InChI=1S/C10H10ClN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	QANNWEVJDHKTEL-UHFFFAOYSA-N	50334201	7-Cl-Marsanidine::CHEMBL1641690	Alpha-2A adrenergic receptor					 15					ChEMBL	10.1016/j.bmc.2010.11.020	10.7270/Q2FQ9WX5	21129985			Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334201&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53323136	125084303		CHEMBL1641690				ZINC66260232	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50608358	CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccccc1	InChI=1S/C18H20N4O2S/c1-21-9-11-22(12-10-21)14-7-8-17-16(13-14)18(20-19-17)25(23,24)15-5-3-2-4-6-15/h2-8,13H,9-12H2,1H3,(H,19,20)	SVLOBFJUUCMSOY-UHFFFAOYSA-N	50330533	5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-indazole::CHEMBL1277917	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1021/jm1007825	10.7270/Q2GQ6XZ6	20932009			Liu, KG; Robichaud, AJ; Bernotas, RC; Yan, Y; Lo, JR; Zhang, MY; Hughes, ZA; Huselton, C; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330533&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10383646	123109648		CHEMBL1277917				ZINC38696951	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50608359	CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12	InChI=1S/C22H22N4O2S/c1-25-11-13-26(14-12-25)17-9-10-20-19(15-17)22(24-23-20)29(27,28)21-8-4-6-16-5-2-3-7-18(16)21/h2-10,15H,11-14H2,1H3,(H,23,24)	OQGLQARWXJXSKS-UHFFFAOYSA-N	50330511	5-(4-Methylpiperazin-1-yl)-3-(1-naphthalenesulfonyl)-1H-indazole::CHEMBL1277104	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1021/jm1007825	10.7270/Q2GQ6XZ6	20932009			Liu, KG; Robichaud, AJ; Bernotas, RC; Yan, Y; Lo, JR; Zhang, MY; Hughes, ZA; Huselton, C; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330511&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9978683	123109626		CHEMBL1277104				ZINC03820933	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50608360	O=S(=O)(c1n[nH]c2ccc(cc12)N1CCNCC1)c1cccc2ccccc12	InChI=1S/C21H20N4O2S/c26-28(27,20-7-3-5-15-4-1-2-6-17(15)20)21-18-14-16(8-9-19(18)23-24-21)25-12-10-22-11-13-25/h1-9,14,22H,10-13H2,(H,23,24)	FYOVZCDHYOEKDE-UHFFFAOYSA-N	50330512	3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole::CHEMBL1277105	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1021/jm1007825	10.7270/Q2GQ6XZ6	20932009			Liu, KG; Robichaud, AJ; Bernotas, RC; Yan, Y; Lo, JR; Zhang, MY; Hughes, ZA; Huselton, C; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330512&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10430623	123109627		CHEMBL1277105				ZINC03820936	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50608361	Cn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12	InChI=1S/C22H22N4O2S/c1-25-20-10-9-17(26-13-11-23-12-14-26)15-19(20)22(24-25)29(27,28)21-8-4-6-16-5-2-3-7-18(16)21/h2-10,15,23H,11-14H2,1H3	IKUNVINCAHHDMJ-UHFFFAOYSA-N	50330516	1-methyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole::CHEMBL1277565	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1021/jm1007825	10.7270/Q2GQ6XZ6	20932009			Liu, KG; Robichaud, AJ; Bernotas, RC; Yan, Y; Lo, JR; Zhang, MY; Hughes, ZA; Huselton, C; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330516&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44554395	123109631		CHEMBL1277565				ZINC64454230	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50608362	CC(C)n1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12	InChI=1S/C24H26N4O2S/c1-17(2)28-22-11-10-19(27-14-12-25-13-15-27)16-21(22)24(26-28)31(29,30)23-9-5-7-18-6-3-4-8-20(18)23/h3-11,16-17,25H,12-15H2,1-2H3	YKEFFXDXDCCGLC-UHFFFAOYSA-N	50330522	1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole::CHEMBL1277837	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1021/jm1007825	10.7270/Q2GQ6XZ6	20932009			Liu, KG; Robichaud, AJ; Bernotas, RC; Yan, Y; Lo, JR; Zhang, MY; Hughes, ZA; Huselton, C; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330522&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44554227	123109637		CHEMBL1277837				ZINC64447293	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50608363	CC(C)Cn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12	InChI=1S/C25H28N4O2S/c1-18(2)17-29-23-11-10-20(28-14-12-26-13-15-28)16-22(23)25(27-29)32(30,31)24-9-5-7-19-6-3-4-8-21(19)24/h3-11,16,18,26H,12-15,17H2,1-2H3	JJOOPJBXZHKRLQ-UHFFFAOYSA-N	50330524	1-isobutyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole::CHEMBL1275630	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1021/jm1007825	10.7270/Q2GQ6XZ6	20932009			Liu, KG; Robichaud, AJ; Bernotas, RC; Yan, Y; Lo, JR; Zhang, MY; Hughes, ZA; Huselton, C; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330524&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44554393	123109639		CHEMBL1275630				ZINC64447513	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50608364	O=S(=O)(c1nn(Cc2ccccc2)c2ccc(cc12)N1CCNCC1)c1cccc2ccccc12	InChI=1S/C28H26N4O2S/c33-35(34,27-12-6-10-22-9-4-5-11-24(22)27)28-25-19-23(31-17-15-29-16-18-31)13-14-26(25)32(30-28)20-21-7-2-1-3-8-21/h1-14,19,29H,15-18,20H2	CPKUIKQUAANRIQ-UHFFFAOYSA-N	50330526	1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole::CHEMBL1278001	Alpha-2A adrenergic receptor		>5000								ChEMBL	10.1021/jm1007825	10.7270/Q2GQ6XZ6	20932009			Liu, KG; Robichaud, AJ; Bernotas, RC; Yan, Y; Lo, JR; Zhang, MY; Hughes, ZA; Huselton, C; Zhang, GM; Zhang, JY; Kowal, DM; Smith, DL; Schechter, LE; Comery, TA	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330526	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330526&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44537940	123109641		CHEMBL1278001				ZINC64453926	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50617231	Fc1cccc(CCN[C@@H]2C3C4CC5C6CC(C3C46)C25)c1	InChI=1S/C19H22FN/c20-10-3-1-2-9(6-10)4-5-21-19-16-12-8-13-15-11(12)7-14(16)17(15)18(13)19/h1-3,6,11-19,21H,4-5,7-8H2/t11?,12?,13?,14?,15?,16?,17?,18?,19-/m0/s1	FZIIBLBHXXRTMG-RAOGCBAWSA-N	50334455	CHEMBL1643900::N-(2-(3'-Fluorophenyl)ethyl)-8-aminopentacyclo[5.4.0.02,6.03,10.05,9]undecane	Alpha-2A adrenergic receptor		 7609								ChEMBL	10.1016/j.bmcl.2010.11.075	10.7270/Q20K28VR	21146989			Banister, SD; Moussa, IA; Beinat, C; Reynolds, AJ; Schiavini, P; Jorgensen, WT; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334455	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334455&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53324553	125084557		CHEMBL1643900					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50658049	OC12CC3CC(CC(C3)N1Cc1ccccc1)C2	InChI=1S/C16H21NO/c18-16-9-13-6-14(10-16)8-15(7-13)17(16)11-12-4-2-1-3-5-12/h1-5,13-15,18H,6-11H2	MJNYRQGREJARAA-UHFFFAOYSA-N	50352160	CHEMBL1824777	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2011.07.028	10.7270/Q2S46SCV	21788137			Banister, SD; Yoo, DT; Chua, SW; Cui, J; Mach, RH; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352160&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56665110	136358846		CHEMBL1824777				ZINC72105237	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50708022	C(C1=NCCN1)n1ncc2ccccc12	InChI=1S/C11H12N4/c1-2-4-10-9(3-1)7-14-15(10)8-11-12-5-6-13-11/h1-4,7H,5-6,8H2,(H,12,13)	GIAVXUIIVFNZAS-UHFFFAOYSA-N	50360000	CHEMBL1928316	Alpha-2A adrenergic receptor					 4500					ChEMBL	10.1016/j.bmc.2011.11.025	10.7270/Q2DJ5G10	22172308			Saczewski, J; Hudson, A; Scheinin, M; Rybczynska, A; Ma, D; Saczewski, F; Laird, S; Laurila, JM; Boblewski, K; Lehmann, A; Gu, J; Watts, H	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360000&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57391904	136964062		CHEMBL1928316				ZINC73292123	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50708023	Cc1cccc2cnn(CC3=NCCN3)c12	InChI=1S/C12H14N4/c1-9-3-2-4-10-7-15-16(12(9)10)8-11-13-5-6-14-11/h2-4,7H,5-6,8H2,1H3,(H,13,14)	CHIFEYGVHJOXNJ-UHFFFAOYSA-N	50360001	CHEMBL1928322	Alpha-2A adrenergic receptor					 17400					ChEMBL	10.1016/j.bmc.2011.11.025	10.7270/Q2DJ5G10	22172308			Saczewski, J; Hudson, A; Scheinin, M; Rybczynska, A; Ma, D; Saczewski, F; Laird, S; Laurila, JM; Boblewski, K; Lehmann, A; Gu, J; Watts, H	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360001&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57400570	136964063		CHEMBL1928322				ZINC73279881	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50708024	Clc1cccc2cnn(CC3=NCCN3)c12	InChI=1S/C11H11ClN4/c12-9-3-1-2-8-6-15-16(11(8)9)7-10-13-4-5-14-10/h1-3,6H,4-5,7H2,(H,13,14)	NNSKKTLFCQUBET-UHFFFAOYSA-N	50360002	CHEMBL1928323	Alpha-2A adrenergic receptor					 16600					ChEMBL	10.1016/j.bmc.2011.11.025	10.7270/Q2DJ5G10	22172308			Saczewski, J; Hudson, A; Scheinin, M; Rybczynska, A; Ma, D; Saczewski, F; Laird, S; Laurila, JM; Boblewski, K; Lehmann, A; Gu, J; Watts, H	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360002&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56950526	136964064		CHEMBL1928323				ZINC73258668	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50708025	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor					 30					ChEMBL	10.1016/j.bmc.2011.11.025	10.7270/Q2DJ5G10	22172308			Saczewski, J; Hudson, A; Scheinin, M; Rybczynska, A; Ma, D; Saczewski, F; Laird, S; Laurila, JM; Boblewski, K; Lehmann, A; Gu, J; Watts, H	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50708026	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2A adrenergic receptor					 118					ChEMBL	10.1016/j.bmc.2011.11.025	10.7270/Q2DJ5G10	22172308			Saczewski, J; Hudson, A; Scheinin, M; Rybczynska, A; Ma, D; Saczewski, F; Laird, S; Laurila, JM; Boblewski, K; Lehmann, A; Gu, J; Watts, H	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732106	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCCCCCCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C52H72N6O4/c59-45-21-19-33-31-57-27-23-37-35-15-9-11-17-41(35)55-49(37)43(57)29-39(33)47(45)51(61)53-25-13-7-5-3-1-2-4-6-8-14-26-54-52(62)48-40-30-44-50-38(36-16-10-12-18-42(36)56-50)24-28-58(44)32-34(40)20-22-46(48)60/h9-12,15-18,33-34,39-40,43-48,55-56,59-60H,1-8,13-14,19-32H2,(H,53,61)(H,54,62)/t33-,34-,39-,40-,43-,44-,45-,46-,47+,48+/m0/s1	UAHJZOOCQKSYMU-MZEGINPWSA-N	50087145	1N-{12-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]dodecyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[ ; dihydrochloride::CHEMBL551711	Alpha-2A adrenergic receptor		 1.2								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087145&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371848	103986224		CHEMBL551711				ZINC96299284	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732112	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C44H56N6O4/c51-37-13-11-25-23-49-19-15-29-27-7-1-3-9-33(27)47-41(29)35(49)21-31(25)39(37)43(53)45-17-5-6-18-46-44(54)40-32-22-36-42-30(28-8-2-4-10-34(28)48-42)16-20-50(36)24-26(32)12-14-38(40)52/h1-4,7-10,25-26,31-32,35-40,47-48,51-52H,5-6,11-24H2,(H,45,53)(H,46,54)/t25-,26-,31-,32-,35-,36-,37-,38-,39+,40+/m0/s1	KFMHLMMVJDAMBL-QRMJEQFMSA-N	50087146	1N-{4-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]butyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2 ;dihydrochloride::CHEMBL539824	Alpha-2A adrenergic receptor		 15								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087146&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12114851	103986225		CHEMBL539824				ZINC95539836	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732113	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C48H64N6O4/c55-41-17-15-29-27-53-23-19-33-31-11-5-7-13-37(31)51-45(33)39(53)25-35(29)43(41)47(57)49-21-9-3-1-2-4-10-22-50-48(58)44-36-26-40-46-34(32-12-6-8-14-38(32)52-46)20-24-54(40)28-30(36)16-18-42(44)56/h5-8,11-14,29-30,35-36,39-44,51-52,55-56H,1-4,9-10,15-28H2,(H,49,57)(H,50,58)/t29-,30-,35-,36-,39-,40-,41-,42-,43+,44+/m0/s1	PRNVEOXPKRXUQW-XDMILYRNSA-N	50087149	1N-{8-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]octyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2 ; dihydrochloride::CHEMBL538808	Alpha-2A adrenergic receptor		 0.760000								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087149	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087149&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11765813	103986228		CHEMBL538808				ZINC95539736	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732115	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCCCCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C50H68N6O4/c57-43-19-17-31-29-55-25-21-35-33-13-7-9-15-39(33)53-47(35)41(55)27-37(31)45(43)49(59)51-23-11-5-3-1-2-4-6-12-24-52-50(60)46-38-28-42-48-36(34-14-8-10-16-40(34)54-48)22-26-56(42)30-32(38)18-20-44(46)58/h7-10,13-16,31-32,37-38,41-46,53-54,57-58H,1-6,11-12,17-30H2,(H,51,59)(H,52,60)/t31-,32-,37-,38-,41-,42-,43-,44-,45+,46+/m0/s1	ATDRGNLOJPZRDO-PMRKYLCGSA-N	50087151	1N-{10-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]decyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3, ;dihydrochloride::CHEMBL554019	Alpha-2A adrenergic receptor		 0.390000								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087151&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10056237	103986230		CHEMBL554019				ZINC95539943	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732118	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 0.420000								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732119	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C43H54N6O4/c50-36-12-10-24-22-48-18-14-28-26-6-1-3-8-32(26)46-40(28)34(48)20-30(24)38(36)42(52)44-16-5-17-45-43(53)39-31-21-35-41-29(27-7-2-4-9-33(27)47-41)15-19-49(35)23-25(31)11-13-37(39)51/h1-4,6-9,24-25,30-31,34-39,46-47,50-51H,5,10-23H2,(H,44,52)(H,45,53)/t24-,25-,30-,31-,34-,35-,36-,37-,38+,39+/m0/s1	OIXDQFQFMZDLEJ-XGOPIZSISA-N	50087150	1N-{3-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]propyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3, ;dihydrochloride::CHEMBL540594	Alpha-2A adrenergic receptor		 52								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087150&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10101373	103986229		CHEMBL540594				ZINC95540105	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732120	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C47H62N6O4/c54-40-16-14-28-26-52-22-18-32-30-10-4-6-12-36(30)50-44(32)38(52)24-34(28)42(40)46(56)48-20-8-2-1-3-9-21-49-47(57)43-35-25-39-45-33(31-11-5-7-13-37(31)51-45)19-23-53(39)27-29(35)15-17-41(43)55/h4-7,10-13,28-29,34-35,38-43,50-51,54-55H,1-3,8-9,14-27H2,(H,48,56)(H,49,57)/t28-,29-,34-,35-,38-,39-,40-,41-,42+,43+/m0/s1	MCEACDKESZXNJS-PJNBFDTGSA-N	50087152	1N-{7-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]heptyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3, ;dihydrochloride::CHEMBL543232	Alpha-2A adrenergic receptor		 0.870000								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087152&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12114852	103986231		CHEMBL543232				ZINC95540028	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732121	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C42H52N6O4/c49-35-11-9-23-21-47-17-13-27-25-5-1-3-7-31(25)45-39(27)33(47)19-29(23)37(35)41(51)43-15-16-44-42(52)38-30-20-34-40-28(26-6-2-4-8-32(26)46-40)14-18-48(34)22-24(30)10-12-36(38)50/h1-8,23-24,29-30,33-38,45-46,49-50H,9-22H2,(H,43,51)(H,44,52)/t23-,24-,29-,30-,33-,34-,35-,36-,37+,38+/m0/s1	JXZAFCOUVYXIBI-KKYULSIISA-N	50087153	1N-{2-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]ethyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2 ;dihydrochloride::CHEMBL542520	Alpha-2A adrenergic receptor		 26								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087153&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12114850	103986232		CHEMBL542520				ZINC95539989	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732122	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C46H60N6O4/c53-39-15-13-27-25-51-21-17-31-29-9-3-5-11-35(29)49-43(31)37(51)23-33(27)41(39)45(55)47-19-7-1-2-8-20-48-46(56)42-34-24-38-44-32(30-10-4-6-12-36(30)50-44)18-22-52(38)26-28(34)14-16-40(42)54/h3-6,9-12,27-28,33-34,37-42,49-50,53-54H,1-2,7-8,13-26H2,(H,47,55)(H,48,56)/t27-,28-,33-,34-,37-,38-,39-,40-,41+,42+/m0/s1	UZUAOFPNPRNPDQ-APDMBNHUSA-N	50087147	1N-{6-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]hexyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2 ;dihydrochloride::CHEMBL542527	Alpha-2A adrenergic receptor		 1.4								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087147&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10123375	103986226		CHEMBL542527				ZINC95539827	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732123	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCCCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C49H66N6O4/c56-42-18-16-30-28-54-24-20-34-32-12-6-8-14-38(32)52-46(34)40(54)26-36(30)44(42)48(58)50-22-10-4-2-1-3-5-11-23-51-49(59)45-37-27-41-47-35(33-13-7-9-15-39(33)53-47)21-25-55(41)29-31(37)17-19-43(45)57/h6-9,12-15,30-31,36-37,40-45,52-53,56-57H,1-5,10-11,16-29H2,(H,50,58)(H,51,59)/t30-,31-,36-,37-,40-,41-,42-,43-,44+,45+/m0/s1	VRGYNRWBJRCLQF-UEQFKLPZSA-N	50087148	1N-{9-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]nonyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2 ;dihydrochloride::CHEMBL539606	Alpha-2A adrenergic receptor		 1.3								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087148&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12114853	103986227		CHEMBL539606				ZINC95543873	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732126	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C45H58N6O4/c52-38-14-12-26-24-50-20-16-30-28-8-2-4-10-34(28)48-42(30)36(50)22-32(26)40(38)44(54)46-18-6-1-7-19-47-45(55)41-33-23-37-43-31(29-9-3-5-11-35(29)49-43)17-21-51(37)25-27(33)13-15-39(41)53/h2-5,8-11,26-27,32-33,36-41,48-49,52-53H,1,6-7,12-25H2,(H,46,54)(H,47,55)/t26-,27-,32-,33-,36-,37-,38-,39-,40+,41+/m0/s1	BHZYDNYEQNZRJY-FPGXKDDPSA-N	50087154	1N-{5-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]pentyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3, ;dihydrochloride::CHEMBL555190	Alpha-2A adrenergic receptor		 1.7								ChEMBL	10.1016/s0960-894x(00)00068-8	10.7270/Q2WM1DXB	10762040			Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087154&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10350094	103986233		CHEMBL555190				ZINC95540083	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729584	CCCC1=C(C(C(C(=O)NCC)C(CC)=N1)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C40H49N5O4/c1-4-14-34-37(35(29-19-21-32(22-20-29)45(48)49)36(33(5-2)43-34)38(46)41-6-3)39(47)42-25-13-26-44-27-23-40(24-28-44,30-15-9-7-10-16-30)31-17-11-8-12-18-31/h7-12,15-22,35-36H,4-6,13-14,23-28H2,1-3H3,(H,41,46)(H,42,47)	QQBCCUCHUBUQEQ-UHFFFAOYSA-N	50081819	2-Ethyl-4-(4-nitro-phenyl)-6-propyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide} 3-ethylamide::CHEMBL316495	Alpha-2A adrenergic receptor		 955								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081819&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931162	103981758		CHEMBL316495				ZINC26717919	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729595	CCC1=NC(COC)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C37H43N5O5/c1-3-30-33(35(38)43)32(26-15-17-29(18-16-26)42(45)46)34(31(40-30)25-47-2)36(44)39-21-10-22-41-23-19-37(20-24-41,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-18,32-33H,3,10,19-25H2,1-2H3,(H2,38,43)(H,39,44)	SPIJYUMJUFXBOQ-UHFFFAOYSA-N	50081821	2-Ethyl-6-methoxymethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL100045	Alpha-2A adrenergic receptor		 575								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081821&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931164	103981760		CHEMBL100045				ZINC26734616	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729604	CCNC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(COCCN)N=C1CC)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C40H50N6O5/c1-3-33-36(38(47)42-4-2)35(29-16-18-32(19-17-29)46(49)50)37(34(44-33)28-51-27-22-41)39(48)43-23-11-24-45-25-20-40(21-26-45,30-12-7-5-8-13-30)31-14-9-6-10-15-31/h5-10,12-19,35-36H,3-4,11,20-28,41H2,1-2H3,(H,42,47)(H,43,48)	GZYMKAZAURLMJX-UHFFFAOYSA-N	50081826	2-(2-Amino-ethoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide} 5-ethylamide::CHEMBL95290	Alpha-2A adrenergic receptor		 1698								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081826&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931169	103981765		CHEMBL95290				ZINC26725927	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729618	CCC1=NC(CCCCOC)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C40H49N5O5/c1-3-33-36(38(41)46)35(29-18-20-32(21-19-29)45(48)49)37(34(43-33)17-10-11-28-50-2)39(47)42-24-12-25-44-26-22-40(23-27-44,30-13-6-4-7-14-30)31-15-8-5-9-16-31/h4-9,13-16,18-21,35-36H,3,10-12,17,22-28H2,1-2H3,(H2,41,46)(H,42,47)	NSXUBFCOCMDGJL-UHFFFAOYSA-N	50081817	2-Ethyl-6-(4-methoxy-butyl)-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL99864	Alpha-2A adrenergic receptor		 99								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081817&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931161	103981756		CHEMBL99864				ZINC26735766	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729632	CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H41N5O4/c1-25-31(34(37)42)33(27-15-17-30(18-16-27)41(44)45)32(26(2)39-25)35(43)38-21-9-10-22-40-23-19-36(20-24-40,28-11-5-3-6-12-28)29-13-7-4-8-14-29/h3-8,11-18,31,33H,9-10,19-24H2,1-2H3,(H2,37,42)(H,38,43)	SQEOIKNCNRHYGE-UHFFFAOYSA-N	50160146	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[4-(4,4-diphenyl-piperidin-1-yl)-butyl]-amide}::CHEMBL180561	Alpha-2A adrenergic receptor		 369								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160146&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91933253	104046706		CHEMBL180561				ZINC28342210	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729648	CCC1=NC(COCCN=[N+]=[N-])=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C38H44N8O5/c1-2-31-34(36(39)47)33(27-14-16-30(17-15-27)46(49)50)35(32(43-31)26-51-25-21-42-44-40)37(48)41-20-9-22-45-23-18-38(19-24-45,28-10-5-3-6-11-28)29-12-7-4-8-13-29/h3-8,10-17,33-34H,2,9,18-26H2,1H3,(H2,39,47)(H,41,48)	RUEVDDMZSNRBBA-UHFFFAOYSA-N	50081824	2-(2-Azido-ethoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-amide 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL98063	Alpha-2A adrenergic receptor		 468								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081824&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931167	103981763		CHEMBL98063				ZINC26717909	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729657	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2A adrenergic receptor		 2417								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729659	CCC1=NC(COCCN)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C38H46N6O5/c1-2-31-34(36(40)45)33(27-14-16-30(17-15-27)44(47)48)35(32(42-31)26-49-25-20-39)37(46)41-21-9-22-43-23-18-38(19-24-43,28-10-5-3-6-11-28)29-12-7-4-8-13-29/h3-8,10-17,33-34H,2,9,18-26,39H2,1H3,(H2,40,45)(H,41,46)	XIIKDAODIFECTH-UHFFFAOYSA-N	50081818	2-(2-Amino-ethoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-amide 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL323579	Alpha-2A adrenergic receptor		 403								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081818&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91518586	103981757		CHEMBL323579				ZINC26724522	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729664	CCC1=NC(COCC(F)(F)F)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C38H42F3N5O5/c1-2-30-33(35(42)47)32(26-14-16-29(17-15-26)46(49)50)34(31(44-30)24-51-25-38(39,40)41)36(48)43-20-9-21-45-22-18-37(19-23-45,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17,32-33H,2,9,18-25H2,1H3,(H2,42,47)(H,43,48)	NFZNWSQRGYZNCQ-UHFFFAOYSA-N	50081828	2-Ethyl-4-(4-nitro-phenyl)-6-(2,2,2-trifluoro-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL320736	Alpha-2A adrenergic receptor		 2308								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081828&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931171	103981767		CHEMBL320736				ZINC26726005	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50729668	CCC1=NC(COCCCN)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C39H48N6O5/c1-2-32-35(37(41)46)34(28-15-17-31(18-16-28)45(48)49)36(33(43-32)27-50-26-9-21-40)38(47)42-22-10-23-44-24-19-39(20-25-44,29-11-5-3-6-12-29)30-13-7-4-8-14-30/h3-8,11-18,34-35H,2,9-10,19-27,40H2,1H3,(H2,41,46)(H,42,47)	UTCOMQXMXQJEDA-UHFFFAOYSA-N	50081823	2-(3-Amino-propoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-amide 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL95578	Alpha-2A adrenergic receptor		 813								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081823&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931166	103981762		CHEMBL95578				ZINC26725039	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50735438	COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4cccc(C)c4)c3c2=O)CC1	InChI=1S/C26H28N4O3S/c1-18-6-5-7-19(16-18)20-17-34-24-23(20)25(31)30(26(32)27-24)15-12-28-10-13-29(14-11-28)21-8-3-4-9-22(21)33-2/h3-9,16-17H,10-15H2,1-2H3,(H,27,32)	PANBMHHKBRMYAL-UHFFFAOYSA-N	50099325	3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-5-m-tolyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::A-123189::CHEMBL13856	Alpha-2A adrenergic receptor		 83								ChEMBL	10.1016/s0960-894x(01)00159-7	10.7270/Q20V8DBQ	11354357			Carroll, WA; Sippy, KB; Esbenshade, TA; Buckner, SA; Hancock, AA; Meyer, MD	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099325&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9891167	103996241		CHEMBL13856		491		ZINC34014527	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50735449	COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4ccccc4)c3c2=O)CC1	InChI=1S/C25H26N4O3S/c1-32-21-10-6-5-9-20(21)28-14-11-27(12-15-28)13-16-29-24(30)22-19(18-7-3-2-4-8-18)17-33-23(22)26-25(29)31/h2-10,17H,11-16H2,1H3,(H,26,31)	HLVQBOYEHQRWHG-UHFFFAOYSA-N	50099322	3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-5-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::A-119637::CHEMBL268758	Alpha-2A adrenergic receptor		 78								ChEMBL	10.1016/s0960-894x(01)00159-7	10.7270/Q20V8DBQ	11354357			Carroll, WA; Sippy, KB; Esbenshade, TA; Buckner, SA; Hancock, AA; Meyer, MD	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099322	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099322&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9890547	103996238		CHEMBL268758		490		ZINC01487800	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50779608	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2A adrenergic receptor		 66								ChEMBL	10.1021/jm960012o	10.7270/Q2NZ889J	8632424			Munk, SA; Lai, RK; Burke, JE; Arasasingham, PN; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Wijono, MK; Hasson, DW; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50779610	CC(C)C1C2CCC(C2)C1N	InChI=1S/C10H19N/c1-6(2)9-7-3-4-8(5-7)10(9)11/h6-10H,3-5,11H2,1-2H3	SHXVJSFOJHMEEQ-UHFFFAOYSA-N	50050094	3-Isopropyl-bicyclo[2.2.1]hept-2-ylamine::CHEMBL430112	Alpha-2A adrenergic receptor		>20000								ChEMBL	10.1021/jm960012o	10.7270/Q2NZ889J	8632424			Munk, SA; Lai, RK; Burke, JE; Arasasingham, PN; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Wijono, MK; Hasson, DW; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050094&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2068	103947281		CHEMBL430112				ZINC03871453	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50779614	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 3.8								ChEMBL	10.1021/jm960012o	10.7270/Q2NZ889J	8632424			Munk, SA; Lai, RK; Burke, JE; Arasasingham, PN; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Wijono, MK; Hasson, DW; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50779620	COc1nc(C)nc(Cl)c1N=C1NCCN1	InChI=1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15)	WPNJAUFVNXKLIM-UHFFFAOYSA-N	50050093	(4-Chloro-6-methoxy-2-methyl-pyrimidin-5-yl)-imidazolidin-2-ylidene-amine::2-(4-Chloro-6-methoxy-2-methyl-pyrimidin-5-ylamino)-4,5-dihydro-3H-imidazol-1-ium::CHEMBL19236::MOXONIDINE	Alpha-2A adrenergic receptor		 150								ChEMBL	10.1021/jm960012o	10.7270/Q2NZ889J	8632424			Munk, SA; Lai, RK; Burke, JE; Arasasingham, PN; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Wijono, MK; Hasson, DW; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050093&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4810	103947280		CHEMBL19236				ZINC01854466	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50768891	OC(c1cnc[nH]1)c1cccc2ccccc12	InChI=1S/C14H12N2O/c17-14(13-8-15-9-16-13)12-7-3-5-10-4-1-2-6-11(10)12/h1-9,14,17H,(H,15,16)	GABDNCQOTDJOGF-UHFFFAOYSA-N	50036911	(1H-Imidazol-4-yl)-naphthalen-1-yl-methanol; hydrochloride::CHEMBL542155	Alpha-2A adrenergic receptor			 61900							ChEMBL	10.1021/jm00041a011	10.7270/Q26110ZR	7914537			Hong, SS; Romstedt, KJ; Feller, DR; Hsu, FL; Cupps, TL; Lyon, RA; Miller, DD	Ohio State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036911&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10376336	103944552		CHEMBL542155				ZINC13737889	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50768893	OC(c1cnc[nH]1)(c1cccc2ccccc12)C(F)(F)F	InChI=1S/C15H11F3N2O/c16-15(17,18)14(21,13-8-19-9-20-13)12-7-3-5-10-4-1-2-6-11(10)12/h1-9,21H,(H,19,20)	VASFQKHCJCIREU-UHFFFAOYSA-N	50036912	2,2,2-Trifluoro-1-(1H-imidazol-4-yl)-1-naphthalen-1-yl-ethanol; hydrochloride::CHEMBL541302	Alpha-2A adrenergic receptor			>300000							ChEMBL	10.1021/jm00041a011	10.7270/Q26110ZR	7914537			Hong, SS; Romstedt, KJ; Feller, DR; Hsu, FL; Cupps, TL; Lyon, RA; Miller, DD	Ohio State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036912	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036912&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11779076	103944553		CHEMBL541302				ZINC13737894	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50768894	CC(c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)	CUHVIMMYOGQXCV-UHFFFAOYSA-N	50036913	(+-)-4-(alpha,2,3-trimethylbenzyl)imidazole::4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole::CHEMBL77921::medetomidine	Alpha-2A adrenergic receptor			 3400							ChEMBL	10.1021/jm00041a011	10.7270/Q26110ZR	7914537			Hong, SS; Romstedt, KJ; Feller, DR; Hsu, FL; Cupps, TL; Lyon, RA; Miller, DD	Ohio State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036913	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036913&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68602	103944554	48552	CHEMBL77921				ZINC84397760	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50768900	O=C(c1cnc[nH]1)c1cccc2ccccc12	InChI=1S/C14H10N2O/c17-14(13-8-15-9-16-13)12-7-3-5-10-4-1-2-6-11(10)12/h1-9H,(H,15,16)	WKXLWRUWMISXTI-UHFFFAOYSA-N	50036915	(1H-Imidazol-4-yl)-naphthalen-1-yl-methanone; oxalic acid::CHEMBL75022	Alpha-2A adrenergic receptor			 580400							ChEMBL	10.1021/jm00041a011	10.7270/Q26110ZR	7914537			Hong, SS; Romstedt, KJ; Feller, DR; Hsu, FL; Cupps, TL; Lyon, RA; Miller, DD	Ohio State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036915	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036915&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11775717	103944556		CHEMBL75022				ZINC13737892	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50768905	C(c1cnc[nH]1)c1cccc2ccccc12	InChI=1S/C14H12N2/c1-2-7-14-11(4-1)5-3-6-12(14)8-13-9-15-10-16-13/h1-7,9-10H,8H2,(H,15,16)	PLUJZEYKAMYHOW-UHFFFAOYSA-N	50036914	4-Naphthalen-1-ylmethyl-1H-imidazole; hydrochloride::CHEMBL544765	Alpha-2A adrenergic receptor			 3000							ChEMBL	10.1021/jm00041a011	10.7270/Q26110ZR	7914537			Hong, SS; Romstedt, KJ; Feller, DR; Hsu, FL; Cupps, TL; Lyon, RA; Miller, DD	Ohio State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036914	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036914&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11820372	103944555		CHEMBL544765				ZINC13737887	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50768909	CC(c1cnc[nH]1)c1cccc2ccccc12	InChI=1S/C15H14N2/c1-11(15-9-16-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13/h2-11H,1H3,(H,16,17)	DZSQSLQSMKNVBV-UHFFFAOYSA-N	50036910	4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole::CHEMBL306751	Alpha-2A adrenergic receptor			 9100							ChEMBL	10.1021/jm00041a011	10.7270/Q26110ZR	7914537			Hong, SS; Romstedt, KJ; Feller, DR; Hsu, FL; Cupps, TL; Lyon, RA; Miller, DD	Ohio State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036910&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132111	103944551		CHEMBL306751				ZINC13450482	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50768910	COC(c1cnc[nH]1)c1cccc2ccccc12	InChI=1S/C15H14N2O/c1-18-15(14-9-16-10-17-14)13-8-4-6-11-5-2-3-7-12(11)13/h2-10,15H,1H3,(H,16,17)	GHEFQYDQTKMXST-UHFFFAOYSA-N	50036916	4-(Methoxy-naphthalen-1-yl-methyl)-1H-imidazole; hydrochloride::CHEMBL553835	Alpha-2A adrenergic receptor			 379800							ChEMBL	10.1021/jm00041a011	10.7270/Q26110ZR	7914537			Hong, SS; Romstedt, KJ; Feller, DR; Hsu, FL; Cupps, TL; Lyon, RA; Miller, DD	Ohio State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036916	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036916&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10105615	103944557		CHEMBL553835				ZINC13737891	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773141	COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16+,19-/m0/s1	GRTOGORTSDXSFK-XJTZBENFSA-N	50030612	(7aR,8S,11aS,12aS)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester::CHEMBL123325::RAUWOLFIA SERPENTINA ROOT::ajmalicine	Alpha-2A adrenergic receptor		 8.2								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030612&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	AJN	4WNT	441975	103939461		CHEMBL123325			C09024		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773169	CCc1sc2ccc(Cl)c3CCN(C)Cc1c23	InChI=1S/C14H16ClNS/c1-3-12-10-8-16(2)7-6-9-11(15)4-5-13(17-12)14(9)10/h4-5H,3,6-8H2,1-2H3	BAAUEDJUTZLMAN-UHFFFAOYSA-N	50030615	5-Chloro-1-ethyl-8-methyl-6,7,8,9-tetrahydro-2-thia-8-aza-benzo[cd]azulene::CHEMBL123448::SK&F-106686::SK-106686	Alpha-2A adrenergic receptor		 31								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030615&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10946567	103939464		CHEMBL123448				ZINC27197425	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50792531	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 3.1								ChEMBL	10.1021/jm990277d	10.7270/Q23T9HZ0	10602703			Belliotti, TR; Wustrow, DJ; Brink, WA; Zoski, KT; Shih, YH; Whetzel, SZ; Georgic, LM; Corbin, AE; Akunne, HC; Heffner, TG; Pugsley, TA; Wise, LD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50792560	Clc1ccc(cc1)N1CCN(Cc2ccc3NC(=O)COc3c2)CC1	InChI=1S/C19H20ClN3O2/c20-15-2-4-16(5-3-15)23-9-7-22(8-10-23)12-14-1-6-17-18(11-14)25-13-19(24)21-17/h1-6,11H,7-10,12-13H2,(H,21,24)	UFFHNEZNXKJHFB-UHFFFAOYSA-N	50083342	7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one::CHEMBL346389	Alpha-2A adrenergic receptor			 1100							ChEMBL	10.1021/jm990277d	10.7270/Q23T9HZ0	10602703			Belliotti, TR; Wustrow, DJ; Brink, WA; Zoski, KT; Shih, YH; Whetzel, SZ; Georgic, LM; Corbin, AE; Akunne, HC; Heffner, TG; Pugsley, TA; Wise, LD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9885114	103983035		CHEMBL346389				ZINC53057273	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50792561	Clc1ccc(cc1)N1CCN(Cc2ccc3NC(=O)COc3c2)CC1	InChI=1S/C19H20ClN3O2/c20-15-2-4-16(5-3-15)23-9-7-22(8-10-23)12-14-1-6-17-18(11-14)25-13-19(24)21-17/h1-6,11H,7-10,12-13H2,(H,21,24)	UFFHNEZNXKJHFB-UHFFFAOYSA-N	50083342	7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one::CHEMBL346389	Alpha-2A adrenergic receptor		 411								ChEMBL	10.1021/jm990277d	10.7270/Q23T9HZ0	10602703			Belliotti, TR; Wustrow, DJ; Brink, WA; Zoski, KT; Shih, YH; Whetzel, SZ; Georgic, LM; Corbin, AE; Akunne, HC; Heffner, TG; Pugsley, TA; Wise, LD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9885114	103983035		CHEMBL346389				ZINC53057273	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50771434	COC(=[OH+])C1=C(C)N=C(C)C(C1c1ccc(cc1)[N+]([O-])=O)=C([O-])OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-15-17-30(18-16-27)39(42)43)32(26(2)37-25)35(41)45-24-10-21-38-22-19-36(20-23-38,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,33,41H,10,19-24H2,1-3H3	ISZKYBBFFMQCLL-UHFFFAOYSA-N	50034681	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL290860	Alpha-2A adrenergic receptor		 800								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034681&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9960497	103942846		CHEMBL290860				ZINC29341039	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773185	CN1CCc2c(Cl)ccc3sc(C=C)c(C1)c23	InChI=1S/C14H14ClNS/c1-3-12-10-8-16(2)7-6-9-11(15)4-5-13(17-12)14(9)10/h3-5H,1,6-8H2,2H3	WKXSXFYQPCWZOS-UHFFFAOYSA-N	50030614	5-Chloro-8-methyl-1-vinyl-6,7,8,9-tetrahydro-2-thia-8-aza-benzo[cd]azulene::CHEMBL25467::SK&F-104856::SK-104856::SKF 104856	Alpha-2A adrenergic receptor		 24								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030614&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			126225	103939463		CHEMBL25467				ZINC28758641	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773201	Cc1nc(C)c(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)c(-c2ccc(cc2)[N+]([O-])=O)c1C(N)=O	InChI=1S/C35H37N5O4/c1-24-30(33(36)41)32(26-14-16-29(17-15-26)40(43)44)31(25(2)38-24)34(42)37-20-9-21-39-22-18-35(19-23-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17H,9,18-23H2,1-2H3,(H2,36,41)(H,37,42)	XAFOTAKURAOBIE-UHFFFAOYSA-N	50030617	2,6-Dimethyl-4-(4-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL122671	Alpha-2A adrenergic receptor		 148								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030617&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44348045	103939466		CHEMBL122671				ZINC27195359	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773202	COC(=O)c1c(C)nc(C)c(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)c1-c1cccc(c1)[N+]([O-])=O	InChI=1S/C36H38N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-12-10-17-30(24-27)40(43)44)34(41)37-20-11-21-39-22-18-36(19-23-39,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24H,11,18-23H2,1-3H3,(H,37,41)	LQIROCVOCINDLE-UHFFFAOYSA-N	50030621	5-[3-(4,4-Diphenyl-piperidin-1-yl)-propylcarbamoyl]-2,6-dimethyl-4-(3-nitro-phenyl)-nicotinic acid methyl ester::CHEMBL123102	Alpha-2A adrenergic receptor		 1550								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030621&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44348164	103939470		CHEMBL123102				ZINC27197822	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773207	COC(=O)c1c(C)nc(C)c(C(=O)OCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)c1-c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H37N3O6/c1-25-31(34(40)44-3)33(27-15-17-30(18-16-27)39(42)43)32(26(2)37-25)35(41)45-24-10-21-38-22-19-36(20-23-38,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18H,10,19-24H2,1-3H3	BXERZGFRIILESM-UHFFFAOYSA-N	50030624	2,6-Dimethyl-4-(4-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL123769	Alpha-2A adrenergic receptor		 1023								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030624&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44348163	103939473		CHEMBL123769				ZINC27197813	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773208	CN1CCc2c(Cl)ccc(OCC=C(C)C)c2CC1	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3	MBYSTKNEMJZSIK-UHFFFAOYSA-N	50030623	6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL114166::SK&F-104078::SK-104078::SKF 104078	Alpha-2A adrenergic receptor		 114								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030623&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122295	103939472		CHEMBL114166				ZINC05158824	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773211	COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19+/m0/s1	GRTOGORTSDXSFK-BMYCAMMWSA-N	50030622	(7aS,8S,11aS,12aR)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester::AKUAMMIGINE::CHEMBL122404	Alpha-2A adrenergic receptor		 106								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030622&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1268096	103939471		CHEMBL122404				ZINC53174616	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773220	CN1CCc2c(Cl)ccc3oc(Br)c(C1)c23	InChI=1S/C12H11BrClNO/c1-15-5-4-7-9(14)2-3-10-11(7)8(6-15)12(13)16-10/h2-3H,4-6H2,1H3	NYGANYRUZQPPGP-UHFFFAOYSA-N	50030619	1-Bromo-5-chloro-8-methyl-6,7,8,9-tetrahydro-2-oxa-8-aza-benzo[cd]azulene::CHEMBL123138::SK&F-105854::SK-105854	Alpha-2A adrenergic receptor		 54								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030619&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9839317	103939468		CHEMBL123138		518		ZINC27197433	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773221	CNC(=O)c1c(C)nc(C)c(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)c1-c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H39N5O4/c1-25-31(34(42)37-3)33(27-15-17-30(18-16-27)41(44)45)32(26(2)39-25)35(43)38-21-10-22-40-23-19-36(20-24-40,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18H,10,19-24H2,1-3H3,(H,37,42)(H,38,43)	HCBLAAMIRQXAHR-UHFFFAOYSA-N	50030613	2,6-Dimethyl-4-(4-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide} 5-methylamide::CHEMBL125294	Alpha-2A adrenergic receptor		 398								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030613&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44348028	103939462		CHEMBL125294				ZINC27207228	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773230	CN1CCc2cccc(Cl)c2CC1	InChI=1S/C11H14ClN/c1-13-7-5-9-3-2-4-11(12)10(9)6-8-13/h2-4H,5-8H2,1H3	RSRUDTPYRBLHEO-UHFFFAOYSA-N	66983	6-chloranyl-3-methyl-1,2,4,5-tetrahydro-3-benzazepine;hydrochloride::6-chloro-3-methyl-1,2,4,5-tetrahydro-3-benzazepine;hydrochloride::CHEMBL123349::MLS002172470::SKF 86466::SKF-86466 hydrochloride::SMR001254100::cid_10220250	Alpha-2A adrenergic receptor		 9.4								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66983	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66983&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			123981	252645294		CHEMBL123349			C10970	ZINC00900633	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773231	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2A adrenergic receptor		 3300								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773234	COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1	BLGXFZZNTVWLAY-DIRVCLHFSA-N	50026636	17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic acid methyl ester::CHEMBL10347::RAUWOLSCINE HYDROCHLORIDE::alpha-yohimbine::corynanthidine::isoyohimbine::mesoyohimbine::methyl (16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate::methyl 17alpha-hydroxy-20alpha-yohimban-16beta-carboxylate::rauwolscine	Alpha-2A adrenergic receptor		 4.6								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026636&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			643606	103936228	48565	CHEMBL10347				ZINC03977785	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773250	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 7.5								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50773251	COC(=O)[C@@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19-/m0/s1	BLGXFZZNTVWLAY-DKJBZYCGSA-N	50027058	(1S,2S,4aR,13bS,14aS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2'',3'':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester::(1S,2S,4aR,13bS,14aS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester::2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester::CHEMBL31410::corynantheine	Alpha-2A adrenergic receptor		 1218								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027058&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			92766	103936640	48565	CHEMBL31410		5345		ZINC03861548	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50771448	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)	VCKUSRYTPJJLNI-UHFFFAOYSA-N	50033111	1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine	Alpha-2A adrenergic receptor		 550								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033111&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TZN	4O3F,4O33	5401	103941452	9445	CHEMBL611	DB01162	7302	C07127	ZINC01271441	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50771473	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2A adrenergic receptor		 210								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50771475	COC(=[OH+])C1=C(C)N=C(C)C([C@@H]1c1cccc(c1)[N+]([O-])=O)=C([O-])OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,41H,11,18-23H2,1-3H3/t33-/m1/s1	OCBZSBUOYIQXSP-MGBGTMOVSA-N	50034682	(R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL436150::NIGULDIPINE	Alpha-2A adrenergic receptor		 900								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034682&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6918097	103942847		CHEMBL436150		463		ZINC26384919	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50771483	COC(=[OH+])C1=C(C)N=C(C)C([C@H]1c1cccc(c1)[N+]([O-])=O)=C([O-])OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,41H,11,18-23H2,1-3H3/t33-/m0/s1	OCBZSBUOYIQXSP-XIFFEERXSA-N	50034683	(S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL41929	Alpha-2A adrenergic receptor		 530								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034683&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60602	103942848		CHEMBL41929		487		ZINC26384924	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50771484	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2A adrenergic receptor		 1200								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50786327	COc1ccccc1N1CCN(C[C@H]2CN=C3N2C(=O)Nc2ccccc32)CC1	InChI=1S/C22H25N5O2/c1-29-20-9-5-4-8-19(20)26-12-10-25(11-13-26)15-16-14-23-21-17-6-2-3-7-18(17)24-22(28)27(16)21/h2-9,16H,10-15H2,1H3,(H,24,28)/t16-/m1/s1	FUCGAUZSWYLMRK-MRXNPFEDSA-N	50369383	CHEMBL1788222	Alpha-2A adrenergic receptor		 444								ChEMBL	10.1021/jm970159v	10.7270/Q2GM880H	9703460			Chern, JW; Tao, PL; Wang, KC; Gutcait, A; Liu, SW; Yen, MH; Chien, SL; Rong, JK	National Taiwan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369383&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9865259	160848485		CHEMBL1788222				ZINC26840261	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50786349	COc1ccccc1N1CCN(C[C@H]2CN=C3N2C(SC)=Nc2ccccc32)CC1	InChI=1S/C23H27N5OS/c1-29-21-10-6-5-9-20(21)27-13-11-26(12-14-27)16-17-15-24-22-18-7-3-4-8-19(18)25-23(30-2)28(17)22/h3-10,17H,11-16H2,1-2H3/t17-/m1/s1	DVYBIZHLZSDANU-QGZVFWFLSA-N	50369382	CHEMBL1788223	Alpha-2A adrenergic receptor		 872								ChEMBL	10.1021/jm970159v	10.7270/Q2GM880H	9703460			Chern, JW; Tao, PL; Wang, KC; Gutcait, A; Liu, SW; Yen, MH; Chien, SL; Rong, JK	National Taiwan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369382&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9931977	160848484		CHEMBL1788223				ZINC40784711	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50786375	COc1ccccc1N1CCN(CC2CN3C(=N2)c2ccccc2NC3=O)CC1	InChI=1S/C22H25N5O2/c1-29-20-9-5-4-8-19(20)26-12-10-25(11-13-26)14-16-15-27-21(23-16)17-6-2-3-7-18(17)24-22(27)28/h2-9,16H,10-15H2,1H3,(H,24,28)	ZAKQYSXDZKMEJJ-UHFFFAOYSA-N	50040260	2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-dihydro-3H-imidazo[1,2-c]quinazolin-5-one::CHEMBL302021	Alpha-2A adrenergic receptor		 547								ChEMBL	10.1021/jm970159v	10.7270/Q2GM880H	9703460			Chern, JW; Tao, PL; Wang, KC; Gutcait, A; Liu, SW; Yen, MH; Chien, SL; Rong, JK	National Taiwan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040260&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			19813292	103972320		CHEMBL302021				ZINC22939047	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50786387	COc1ccccc1N1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1	InChI=1S/C21H24N4O3/c1-28-19-9-5-4-8-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-6-2-3-7-17(16)22-21(25)27/h2-9H,10-15H2,1H3,(H,22,27)	ZFDWAPWETDMDSZ-UHFFFAOYSA-N	50040253	3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1H-quinazoline-2,4-dione::CHEMBL51433	Alpha-2A adrenergic receptor		 1811								ChEMBL	10.1021/jm970159v	10.7270/Q2GM880H	9703460			Chern, JW; Tao, PL; Wang, KC; Gutcait, A; Liu, SW; Yen, MH; Chien, SL; Rong, JK	National Taiwan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040253&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122065	103972313		CHEMBL51433				ZINC05115799	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50812899	Cc1c(cccc1-c1ccccc1)N=C1NCCN1	InChI=1S/C16H17N3/c1-12-14(13-6-3-2-4-7-13)8-5-9-15(12)19-16-17-10-11-18-16/h2-9H,10-11H2,1H3,(H2,17,18,19)	MKDJCTAYFLKGEM-UHFFFAOYSA-N	50130287	(4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-3-yl)-amine::CHEMBL92221	Alpha-2A adrenergic receptor		 19								ChEMBL	10.1021/jm030030n	10.7270/Q2M0465F	12825922			Glennon, RA	Virginia Commonwealth University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130287&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10106205	104021721		CHEMBL92221				ZINC13487079	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50812951	CN1CCc2ccc3[C@@H](N)c4cccc5C[C@@H]1c2c3-c45	InChI=1S/C18H18N2/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(13)19/h2-6,14,18H,7-9,19H2,1H3/t14-,18+/m1/s1	DAKGDRVNCPHAPY-KDOFPFPSSA-N	50087024	(1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::CHEMBL27251	Alpha-2A adrenergic receptor		 93								ChEMBL	10.1021/jm030030n	10.7270/Q2M0465F	12825922			Glennon, RA	Virginia Commonwealth University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087024&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10084076	103986134		CHEMBL27251				ZINC13806922	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50814545	CC(N)Cc1c[nH]c2ccc3OCCCc3c12	InChI=1S/C14H18N2O/c1-9(15)7-10-8-16-12-4-5-13-11(14(10)12)3-2-6-17-13/h4-5,8-9,16H,2-3,6-7,15H2,1H3	VVHJUSGIUWQPIT-UHFFFAOYSA-N	50133229	1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine::CHEMBL133868	Alpha-2A adrenergic receptor			>10000							ChEMBL	10.1021/jm030205t	10.7270/Q2Z320C1	12954071			May, JA; Chen, HH; Rusinko, A; Lynch, VM; Sharif, NA; McLaughlin, MA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133229&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9856041	104024141		CHEMBL133868				ZINC13527318	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50814618	C[C@H](N)Cc1c[nH]c2ccc3OCCCc3c12	InChI=1S/C14H18N2O/c1-9(15)7-10-8-16-12-4-5-13-11(14(10)12)3-2-6-17-13/h4-5,8-9,16H,2-3,6-7,15H2,1H3/t9-/m0/s1	VVHJUSGIUWQPIT-VIFPVBQESA-N	50133232	(S)-1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine::CHEMBL133455	Alpha-2A adrenergic receptor			 19000							ChEMBL	10.1021/jm030205t	10.7270/Q2Z320C1	12954071			May, JA; Chen, HH; Rusinko, A; Lynch, VM; Sharif, NA; McLaughlin, MA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133232&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10331436	104024144		CHEMBL133455		160			1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824558	CN(C)c1nc(NC2CCC(CC2)NCc2ccc(Br)cc2OC(F)(F)F)nc2ccccc12	InChI=1S/C24H27BrF3N5O/c1-33(2)22-19-5-3-4-6-20(19)31-23(32-22)30-18-11-9-17(10-12-18)29-14-15-7-8-16(25)13-21(15)34-24(26,27)28/h3-8,13,17-18,29H,9-12,14H2,1-2H3,(H,30,31,32)	PUTAQVRRQAPAQX-UHFFFAOYSA-N	50170175	CHEMBL178084::cis-N*2*-[4-(4-Bromo-2-trifluoromethoxy-benzylamino)-cyclohexyl]-N*4*,N*4*-dimethyl-quinazoline-2,4-diamine	Alpha-2A adrenergic receptor			 170							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170175&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390733	104056617		CHEMBL178084				ZINC28129566	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50834239	C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)\C=C\c1ccc(Cl)cc1NC(C)=O	InChI=1S/C23H25ClFN3O2/c1-16-14-27(15-18-3-8-21(25)9-4-18)11-12-28(16)23(30)10-6-19-5-7-20(24)13-22(19)26-17(2)29/h3-10,13,16H,11-12,14-15H2,1-2H3,(H,26,29)/b10-6+/t16-/m1/s1	DUFKTZBQJIHIAQ-VGZDNEPHSA-N	50174702	(R)-N-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenyl)acetamide::CHEMBL198949	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1016/j.bmcl.2005.08.057	10.7270/Q2C53MMD	16198561			Revesz, L; Bollbuck, B; Buhl, T; Eder, J; Esser, R; Feifel, R; Heng, R; Hiestand, P; Jachez-Demange, B; Loetscher, P; Sparrer, H; Schlapbach, A; Waelchli, R	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174702&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11743399	104060492		CHEMBL198949				ZINC13985934	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824564	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(C)c2)nc2ccccc12	InChI=1S/C24H29N5O/c1-16-7-6-8-17(15-16)23(30)25-18-11-13-19(14-12-18)26-24-27-21-10-5-4-9-20(21)22(28-24)29(2)3/h4-10,15,18-19H,11-14H2,1-3H3,(H,25,30)(H,26,27,28)/t18-,19+	XJARKGGVDJGJMK-KDURUIRLSA-N	50170179	CHEMBL180962::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-3-methyl-benzamide	Alpha-2A adrenergic receptor			 110							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170179&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390778	104056621		CHEMBL180962				ZINC28332761	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824565	CN(C)c1nc(NC2CCC(CNC(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C25H27BrF3N5O2/c1-34(2)22-18-5-3-4-6-20(18)32-24(33-22)31-17-10-7-15(8-11-17)14-30-23(35)19-12-9-16(26)13-21(19)36-25(27,28)29/h3-6,9,12-13,15,17H,7-8,10-11,14H2,1-2H3,(H,30,35)(H,31,32,33)	INNDGUNGHHCVFO-UHFFFAOYSA-N	50170181	CHEMBL181393::cis-4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexylmethyl]-2-trifluoromethoxy-benzamide	Alpha-2A adrenergic receptor			 570							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170181&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10303307	104056623		CHEMBL181393				ZINC28330747	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824567	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(c2)C(F)(F)F)nc2ccccc12	InChI=1S/C24H26F3N5O/c1-32(2)21-19-8-3-4-9-20(19)30-23(31-21)29-18-12-10-17(11-13-18)28-22(33)15-6-5-7-16(14-15)24(25,26)27/h3-9,14,17-18H,10-13H2,1-2H3,(H,28,33)(H,29,30,31)/t17-,18+	BXGRLXRXUOGKTC-HDICACEKSA-N	50170183	CHEMBL181632::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-3-trifluoromethyl-benzamide	Alpha-2A adrenergic receptor			 60							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170183&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390710	104056625		CHEMBL181632				ZINC28332657	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824568	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(Cl)c(Cl)c2)nc2ccccc12	InChI=1S/C23H25Cl2N5O/c1-30(2)21-17-5-3-4-6-20(17)28-23(29-21)27-16-10-8-15(9-11-16)26-22(31)14-7-12-18(24)19(25)13-14/h3-7,12-13,15-16H,8-11H2,1-2H3,(H,26,31)(H,27,28,29)/t15-,16+	UGUPGQUFTPDBTH-IYBDPMFKSA-N	50170182	3,4-Dichloro-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide::CHEMBL362400	Alpha-2A adrenergic receptor			 47							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170182&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390715	104056624		CHEMBL362400				ZINC28333830	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824571	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(F)c(F)c2F)nc2ccccc12	InChI=1S/C23H24F3N5O/c1-31(2)21-15-5-3-4-6-18(15)29-23(30-21)28-14-9-7-13(8-10-14)27-22(32)16-11-12-17(24)20(26)19(16)25/h3-6,11-14H,7-10H2,1-2H3,(H,27,32)(H,28,29,30)/t13-,14+	JJZSKQSMTGTKID-OKILXGFUSA-N	50170185	CHEMBL360159::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-2,3,4-trifluoro-benzamide	Alpha-2A adrenergic receptor			 200							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170185&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390787	104056627		CHEMBL360159				ZINC28338094	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824575	CN(C)c1nc(NC[C@H]2CC[C@H](CNS(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C25H29BrF3N5O3S/c1-34(2)23-19-5-3-4-6-20(19)32-24(33-23)30-14-16-7-9-17(10-8-16)15-31-38(35,36)22-12-11-18(26)13-21(22)37-25(27,28)29/h3-6,11-13,16-17,31H,7-10,14-15H2,1-2H3,(H,30,32,33)/t16-,17-	NWUCPBLQECHRFK-QAQDUYKDSA-N	50170189	4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzenesulfonamide; hydrochloride::CHEMBL537846	Alpha-2A adrenergic receptor			 7.7							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170189&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9895868	104056631		CHEMBL537846				ZINC28332800	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824579	CN(C)c1nc(NC2CCC(CC2)NC(=O)c2ccc(Br)cc2OC(F)(F)F)nc2ccccc12	InChI=1S/C24H25BrF3N5O2/c1-33(2)21-17-5-3-4-6-19(17)31-23(32-21)30-16-10-8-15(9-11-16)29-22(34)18-12-7-14(25)13-20(18)35-24(26,27)28/h3-7,12-13,15-16H,8-11H2,1-2H3,(H,29,34)(H,30,31,32)	NTZDCPIPBYWRFF-UHFFFAOYSA-N	50170190	CHEMBL181184::cis-4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-2-trifluoromethoxy-benzamide	Alpha-2A adrenergic receptor			 390							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170190&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10231050	104056632		CHEMBL181184				ZINC28331528	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824580	CN(C)c1nc(NC2CCC(CNCc3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C25H29BrF3N5O/c1-34(2)23-20-5-3-4-6-21(20)32-24(33-23)31-19-11-7-16(8-12-19)14-30-15-17-9-10-18(26)13-22(17)35-25(27,28)29/h3-6,9-10,13,16,19,30H,7-8,11-12,14-15H2,1-2H3,(H,31,32,33)	ODLVSMAEEPBMLK-UHFFFAOYSA-N	50170192	CHEMBL181466::cis-N*2*-{4-[(4-Bromo-2-trifluoromethoxy-benzylamino)-methyl]-cyclohexyl}-N*4*,N*4*-dimethyl-quinazoline-2,4-diamine	Alpha-2A adrenergic receptor			 360							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170192&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9807658	104056634		CHEMBL181466				ZINC28335373	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824588	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(c2)C#N)nc2ccccc12	InChI=1S/C24H26N6O/c1-30(2)22-20-8-3-4-9-21(20)28-24(29-22)27-19-12-10-18(11-13-19)26-23(31)17-7-5-6-16(14-17)15-25/h3-9,14,18-19H,10-13H2,1-2H3,(H,26,31)(H,27,28,29)/t18-,19+	LNOMHNHLGYHPNB-KDURUIRLSA-N	50170195	3-Cyano-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide::CHEMBL181099	Alpha-2A adrenergic receptor			 150							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170195&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390730	104056637		CHEMBL181099				ZINC28339090	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824589	CN(CC1CCC(CNc2nc(N(C)C)c3ccccc3n2)CC1)Cc1ccc(Br)cc1OC(F)(F)F	InChI=1S/C27H33BrF3N5O/c1-35(2)25-22-6-4-5-7-23(22)33-26(34-25)32-15-18-8-10-19(11-9-18)16-36(3)17-20-12-13-21(28)14-24(20)37-27(29,30)31/h4-7,12-14,18-19H,8-11,15-17H2,1-3H3,(H,32,33,34)	KSWFHJFVFLWBLC-UHFFFAOYSA-N	50170196	CHEMBL182235::trans-N*2*-(4-{[(4-Bromo-2-trifluoromethoxy-benzyl)-methyl-amino]-methyl}-cyclohexylmethyl)-N*4*,N*4*-dimethyl-quinazoline-2,4-diamine	Alpha-2A adrenergic receptor			 44							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170196&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390456	104056638		CHEMBL182235				ZINC28134008	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824592	CN(C)c1nc(N[C@@H]2CC[C@H](CNS(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C24H27BrF3N5O3S/c1-33(2)22-18-5-3-4-6-19(18)31-23(32-22)30-17-10-7-15(8-11-17)14-29-37(34,35)21-12-9-16(25)13-20(21)36-24(26,27)28/h3-6,9,12-13,15,17,29H,7-8,10-11,14H2,1-2H3,(H,30,31,32)/t15-,17+	GPEOXJGBWGMANI-WOVMCDHWSA-N	50170178	4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexylmethyl]-2-trifluoromethoxy-benzenesulfonamide::CHEMBL181217	Alpha-2A adrenergic receptor			 130							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170178&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11284878	104056620		CHEMBL181217				ZINC28336031	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824598	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(Cl)c2)nc2ccccc12	InChI=1S/C23H26ClN5O/c1-29(2)21-19-8-3-4-9-20(19)27-23(28-21)26-18-12-10-17(11-13-18)25-22(30)15-6-5-7-16(24)14-15/h3-9,14,17-18H,10-13H2,1-2H3,(H,25,30)(H,26,27,28)/t17-,18+	PCMKFHUKCPUDQK-HDICACEKSA-N	50170180	3-Chloro-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide::CHEMBL179878	Alpha-2A adrenergic receptor			 76							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170180&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390750	104056622		CHEMBL179878				ZINC28342218	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824600	CN(C)c1nc(NC2CCN(CC2)S(=O)(=O)c2ccc(Br)cc2OC(F)(F)F)nc2ccccc12	InChI=1S/C22H23BrF3N5O3S/c1-30(2)20-16-5-3-4-6-17(16)28-21(29-20)27-15-9-11-31(12-10-15)35(32,33)19-8-7-14(23)13-18(19)34-22(24,25)26/h3-8,13,15H,9-12H2,1-2H3,(H,27,28,29)	AUHFSEIMAYONHH-UHFFFAOYSA-N	50166556	CHEMBL360671::N*2*-[1-(4-Bromo-2-trifluoromethoxy-benzenesulfonyl)-piperidin-4-yl]-N*4*,N*4*-dimethyl-quinazoline-2,4-diamine	Alpha-2A adrenergic receptor			 170							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166556&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11342160	104052014		CHEMBL360671				ZINC28343413	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824604	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(Br)c2)nc2ccccc12	InChI=1S/C23H26BrN5O/c1-29(2)21-19-8-3-4-9-20(19)27-23(28-21)26-18-12-10-17(11-13-18)25-22(30)15-6-5-7-16(24)14-15/h3-9,14,17-18H,10-13H2,1-2H3,(H,25,30)(H,26,27,28)/t17-,18+	RFTNZWFCHDUSMZ-HDICACEKSA-N	50170176	3-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide::CHEMBL359510	Alpha-2A adrenergic receptor			 63							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170176&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390706	104056618		CHEMBL359510				ZINC28332598	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824606	CN(C)c1nc(N[C@H]2CC[C@H](CC2)NS(=O)(=O)c2ccc(Br)cc2OC(F)(F)F)nc2ccccc12	InChI=1S/C23H25BrF3N5O3S/c1-32(2)21-17-5-3-4-6-18(17)29-22(30-21)28-15-8-10-16(11-9-15)31-36(33,34)20-12-7-14(24)13-19(20)35-23(25,26)27/h3-7,12-13,15-16,31H,8-11H2,1-2H3,(H,28,29,30)/t15-,16+	LDCMGLYXOOMRFQ-IYBDPMFKSA-N	50170184	4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-2-trifluoromethoxy-benzenesulfonamide::CHEMBL180003	Alpha-2A adrenergic receptor			 57							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170184&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11204090	104056626		CHEMBL180003				ZINC28334916	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824608	CN(C)c1nc(NCC2CCC(CN(C)S(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C26H31BrF3N5O3S/c1-34(2)24-20-6-4-5-7-21(20)32-25(33-24)31-15-17-8-10-18(11-9-17)16-35(3)39(36,37)23-13-12-19(27)14-22(23)38-26(28,29)30/h4-7,12-14,17-18H,8-11,15-16H2,1-3H3,(H,31,32,33)	KZRCWZJRCYMXFF-UHFFFAOYSA-N	50170187	CHEMBL181727::trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-N-methyl-2-trifluoromethoxy-benzenesulfonamide	Alpha-2A adrenergic receptor			 34							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170187&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390369	104056629		CHEMBL181727				ZINC28331548	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824609	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(F)cc2)nc2ccccc12	InChI=1S/C23H26FN5O/c1-29(2)21-19-5-3-4-6-20(19)27-23(28-21)26-18-13-11-17(12-14-18)25-22(30)15-7-9-16(24)10-8-15/h3-10,17-18H,11-14H2,1-2H3,(H,25,30)(H,26,27,28)/t17-,18+	ZICGUURZNAJJKQ-HDICACEKSA-N	50170199	CHEMBL361442::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-4-fluoro-benzamide	Alpha-2A adrenergic receptor			 150							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170199&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390742	104056641		CHEMBL361442				ZINC28135495	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824611	COc1cc(OC)cc(c1)C(=O)N[C@H]1CC[C@H](CC1)Nc1nc(N(C)C)c2ccccc2n1	InChI=1S/C25H31N5O3/c1-30(2)23-21-7-5-6-8-22(21)28-25(29-23)27-18-11-9-17(10-12-18)26-24(31)16-13-19(32-3)15-20(14-16)33-4/h5-8,13-15,17-18H,9-12H2,1-4H3,(H,26,31)(H,27,28,29)/t17-,18+	FTXAKSJEBVGKHR-HDICACEKSA-N	50170193	CHEMBL360081::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-3,5-dimethoxy-benzamide	Alpha-2A adrenergic receptor			 71							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170193&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390726	104056635		CHEMBL360081				ZINC28341322	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824612	CN(C)c1nc(NCC2CCC(CNCc3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C26H31BrF3N5O/c1-35(2)24-21-5-3-4-6-22(21)33-25(34-24)32-15-18-9-7-17(8-10-18)14-31-16-19-11-12-20(27)13-23(19)36-26(28,29)30/h3-6,11-13,17-18,31H,7-10,14-16H2,1-2H3,(H,32,33,34)	UGTJLUOFSLGNDT-UHFFFAOYSA-N	50170177	CHEMBL360117::trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzamide	Alpha-2A adrenergic receptor			 31							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170177&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390385	104056619		CHEMBL360117				ZINC28133369	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824615	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(F)c2)nc2ccccc12	InChI=1S/C23H26FN5O/c1-29(2)21-19-8-3-4-9-20(19)27-23(28-21)26-18-12-10-17(11-13-18)25-22(30)15-6-5-7-16(24)14-15/h3-9,14,17-18H,10-13H2,1-2H3,(H,25,30)(H,26,27,28)/t17-,18+	IESRGXWBZDJPLC-HDICACEKSA-N	50170198	CHEMBL362193::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-3-fluoro-benzamide	Alpha-2A adrenergic receptor			 130							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170198&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390713	104056640		CHEMBL362193				ZINC28332740	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824616	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(F)c(F)c2)nc2ccccc12	InChI=1S/C23H25F2N5O/c1-30(2)21-17-5-3-4-6-20(17)28-23(29-21)27-16-10-8-15(9-11-16)26-22(31)14-7-12-18(24)19(25)13-14/h3-7,12-13,15-16H,8-11H2,1-2H3,(H,26,31)(H,27,28,29)/t15-,16+	FAIMGWSOSCFGRU-IYBDPMFKSA-N	50170191	CHEMBL182150::N-((cis)-4-(4-(dimethylamino)quinazolin-2-ylamino)cyclohexyl)-3,4-difluorobenzamide::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-3,4-difluoro-benzamide	Alpha-2A adrenergic receptor			 260							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170191&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9934033	104056633		CHEMBL182150		1305		ZINC03961870	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824618	CN(C)c1nc(NCC2CCC(CNC(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C26H29BrF3N5O2/c1-35(2)23-19-5-3-4-6-21(19)33-25(34-23)32-15-17-9-7-16(8-10-17)14-31-24(36)20-12-11-18(27)13-22(20)37-26(28,29)30/h3-6,11-13,16-17H,7-10,14-15H2,1-2H3,(H,31,36)(H,32,33,34)	KENQBAJESGJICP-UHFFFAOYSA-N	50170194	CHEMBL367355::trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzamide	Alpha-2A adrenergic receptor			 9.9							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170194&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390499	104056636		CHEMBL367355				ZINC28333679	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824621	CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(c2)[N+]([O-])=O)nc2ccccc12	InChI=1S/C23H26N6O3/c1-28(2)21-19-8-3-4-9-20(19)26-23(27-21)25-17-12-10-16(11-13-17)24-22(30)15-6-5-7-18(14-15)29(31)32/h3-9,14,16-17H,10-13H2,1-2H3,(H,24,30)(H,25,26,27)/t16-,17+	CYJMDICCNHFYPK-CALCHBBNSA-N	50170200	CHEMBL181383::N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-3-nitro-benzamide	Alpha-2A adrenergic receptor			 97							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170200&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390768	104056642		CHEMBL181383				ZINC28332614	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50824622	CN(C)c1nc(NC2CCN(Cc3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12	InChI=1S/C23H25BrF3N5O/c1-31(2)21-18-5-3-4-6-19(18)29-22(30-21)28-17-9-11-32(12-10-17)14-15-7-8-16(24)13-20(15)33-23(25,26)27/h3-8,13,17H,9-12,14H2,1-2H3,(H,28,29,30)	FFRCQBGVCKTCAM-UHFFFAOYSA-N	50170186	CHEMBL360876::N*2*-[1-(4-Bromo-2-trifluoromethoxy-benzyl)-piperidin-4-yl]-N*4*,N*4*-dimethyl-quinazoline-2,4-diamine	Alpha-2A adrenergic receptor			 520							ChEMBL	10.1016/j.bmcl.2005.05.121	10.7270/Q23R0TM4	16002290			Kanuma, K; Omodera, K; Nishiguchi, M; Funakoshi, T; Chaki, S; Semple, G; Tran, TA; Kramer, B; Hsu, D; Casper, M; Thomsen, B; Sekiguchi, Y	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170186&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44390752	104056628		CHEMBL360876				ZINC28341415	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850280	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3F)Cc2cc1OC	InChI=1S/C27H26FNO4/c1-30-23-9-8-18(21-14-24(33-27(21)23)20-6-4-5-7-22(20)28)15-29-11-10-17-12-25(31-2)26(32-3)13-19(17)16-29/h4-9,12-14H,10-11,15-16H2,1-3H3	NTHIAFXFYRUEJP-UHFFFAOYSA-N	50203554	2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline::CHEMBL393597	Alpha-2A adrenergic receptor		 857								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203554&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11293787	104082635		CHEMBL393597				ZINC28877971	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850283	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccn3)Cc2cc1OC	InChI=1S/C26H26N2O4/c1-29-22-8-7-18(20-14-23(32-26(20)22)21-6-4-5-10-27-21)15-28-11-9-17-12-24(30-2)25(31-3)13-19(17)16-28/h4-8,10,12-14H,9,11,15-16H2,1-3H3	VLMCHIMKCURVRR-UHFFFAOYSA-N	50203556	6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL246229	Alpha-2A adrenergic receptor		 135								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203556&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438148	104082637		CHEMBL246229				ZINC28877933	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850291	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)N3CCC(CC3)N3CCCC3)Cc2cc1OC	InChI=1S/C31H39N3O5/c1-36-26-7-6-22(19-32-13-8-21-16-27(37-2)28(38-3)17-23(21)20-32)25-18-29(39-30(25)26)31(35)34-14-9-24(10-15-34)33-11-4-5-12-33/h6-7,16-18,24H,4-5,8-15,19-20H2,1-3H3	IVEMQVDPOPYVKY-UHFFFAOYSA-N	50203561	(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxybenzofuran-2-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone::CHEMBL247665	Alpha-2A adrenergic receptor		 186								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203561&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438168	104082642		CHEMBL247665				ZINC28878084	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850292	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3)Cc2cc1OC	InChI=1S/C27H27NO4/c1-29-23-10-9-20(22-15-24(32-27(22)23)18-7-5-4-6-8-18)16-28-12-11-19-13-25(30-2)26(31-3)14-21(19)17-28/h4-10,13-15H,11-12,16-17H2,1-3H3	LNYCQEZPPFYNOL-UHFFFAOYSA-N	50203555	6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL392992	Alpha-2A adrenergic receptor		 1742								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203555&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16725934	104082636		CHEMBL392992				ZINC13983081	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850295	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3C(F)(F)F)Cc2cc1OC	InChI=1S/C28H26F3NO4/c1-33-23-9-8-18(15-32-11-10-17-12-25(34-2)26(35-3)13-19(17)16-32)21-14-24(36-27(21)23)20-6-4-5-7-22(20)28(29,30)31/h4-9,12-14H,10-11,15-16H2,1-3H3	RDAVKEYAUFGPDX-UHFFFAOYSA-N	50203563	6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)phenyl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL246852	Alpha-2A adrenergic receptor		 304								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203563&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11225732	104082644		CHEMBL246852				ZINC28877993	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850296	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 1.8								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850298	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccco3)Cc2cc1OC	InChI=1S/C25H25NO5/c1-27-21-7-6-17(19-13-24(31-25(19)21)20-5-4-10-30-20)14-26-9-8-16-11-22(28-2)23(29-3)12-18(16)15-26/h4-7,10-13H,8-9,14-15H2,1-3H3	JXCCNCOVOMQXNP-UHFFFAOYSA-N	50203559	2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline::CHEMBL392991	Alpha-2A adrenergic receptor		 204								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203559&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11750482	104082640		CHEMBL392991				ZINC28877931	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850299	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCC(C)(C)N)Cc2cc1OC	InChI=1S/C26H33N3O5/c1-26(2,27)15-28-25(30)23-12-19-17(6-7-20(31-3)24(19)34-23)13-29-9-8-16-10-21(32-4)22(33-5)11-18(16)14-29/h6-7,10-12H,8-9,13-15,27H2,1-5H3,(H,28,30)	JYEPTVGXWUQMKF-UHFFFAOYSA-N	50203553	CHEMBL247664::N-(2-amino-2-methylpropyl)-4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxybenzofuran-2-carboxamide	Alpha-2A adrenergic receptor		 141								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203553&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438166	104082634		CHEMBL247664				ZINC28878066	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850306	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCCN(C)C)Cc2cc1OC	InChI=1S/C26H33N3O5/c1-28(2)11-9-27-26(30)24-14-20-18(6-7-21(31-3)25(20)34-24)15-29-10-8-17-12-22(32-4)23(33-5)13-19(17)16-29/h6-7,12-14H,8-11,15-16H2,1-5H3,(H,27,30)	IWHCCXKZMXALTR-UHFFFAOYSA-N	50203562	4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-N-(2-(dimethylamino)ethyl)-7-methoxybenzofuran-2-carboxamide::CHEMBL428407	Alpha-2A adrenergic receptor		 454								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203562&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438165	104082643		CHEMBL428407				ZINC28878060	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850309	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NC3CN4CCC3CC4)Cc2cc1OC	InChI=1S/C29H35N3O5/c1-34-24-5-4-20(15-32-11-8-19-12-25(35-2)26(36-3)13-21(19)16-32)22-14-27(37-28(22)24)29(33)30-23-17-31-9-6-18(23)7-10-31/h4-5,12-14,18,23H,6-11,15-17H2,1-3H3,(H,30,33)	RKQFKAILJGXGRP-UHFFFAOYSA-N	50203558	4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxy-N-(quinuclidin-3-yl)benzofuran-2-carboxamide::CHEMBL394218	Alpha-2A adrenergic receptor		 42								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203558&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438167	104082639		CHEMBL394218				ZINC28878079	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850315	COc1cccc(c1)-c1cc2c(CN3CCc4cc(OC)c(OC)cc4C3)ccc(OC)c2o1	InChI=1S/C28H29NO5/c1-30-22-7-5-6-19(12-22)25-15-23-20(8-9-24(31-2)28(23)34-25)16-29-11-10-18-13-26(32-3)27(33-4)14-21(18)17-29/h5-9,12-15H,10-11,16-17H2,1-4H3	HIASAPHKGILEIV-UHFFFAOYSA-N	50203565	6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL246639	Alpha-2A adrenergic receptor		 2552								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203565&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438152	104082646		CHEMBL246639				ZINC28877959	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850317	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2A adrenergic receptor		 8								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850318	COc1cc2CCN(Cc3cnc(N)n4nc(nc34)-c3ccco3)Cc2cc1OC	InChI=1S/C21H22N6O3/c1-28-17-8-13-5-6-26(11-14(13)9-18(17)29-2)12-15-10-23-21(22)27-20(15)24-19(25-27)16-4-3-7-30-16/h3-4,7-10H,5-6,11-12H2,1-2H3,(H2,22,23)	HXHKXXRIQOWOHI-UHFFFAOYSA-N	50203560	8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-f]pyrimidin-5-amine::CHEMBL246228	Alpha-2A adrenergic receptor		 400								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203560&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438147	104082641		CHEMBL246228				ZINC28877925	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50850319	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3cccc(c3)C(=O)NCCN(C)C)Cc2cc1OC	InChI=1S/C32H37N3O5/c1-34(2)14-12-33-32(36)23-8-6-7-22(15-23)28-18-26-24(9-10-27(37-3)31(26)40-28)19-35-13-11-21-16-29(38-4)30(39-5)17-25(21)20-35/h6-10,15-18H,11-14,19-20H2,1-5H3,(H,33,36)	MGJOAQODMQCCGV-UHFFFAOYSA-N	50203557	3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxybenzofuran-2-yl)-N-(2-(dimethylamino)ethyl)benzamide::CHEMBL392771	Alpha-2A adrenergic receptor		 216								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203557&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438161	104082638		CHEMBL392771				ZINC28878039	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50840719	Oc1cc2OCC3NCc4ccccc4C3c2cc1O	InChI=1S/C16H15NO3/c18-13-5-11-15(6-14(13)19)20-8-12-16(11)10-4-2-1-3-9(10)7-17-12/h1-6,12,16-19H,7-8H2	QDUNOUQOKOYLCH-UHFFFAOYSA-N	50200351	(+/-)-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline::CHEMBL217299	Alpha-2A adrenergic receptor		 180								ChEMBL	10.1021/jm0604979	10.7270/Q25T3M92	17154515			Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE	Purdue University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25142456	104080715		CHEMBL217299				ZINC34801104	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50845595	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(12-19-4-6-20(28)7-5-19)15-30-8-10-31(11-9-30)16-26-22-17-34-23-14-25(33-3)24(32-2)13-21(23)27(22)29-35-26/h4-7,12-14,22,26H,8-11,15-17H2,1-3H3/b18-12+/t22-,26-/m0/s1	UCNOTTVNPRSTFW-XSFNXXSESA-N	50146518	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL318235::R-226161::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2A adrenergic receptor		 28.0								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146518&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16655023	104035107		CHEMBL318235				ZINC26742166	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50845596	COc1cc2OCC3C(CN4CCN(C\C=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-12-10-29(11-13-30)9-3-4-18-5-7-19(27)8-6-18/h3-8,14-15,21,25H,9-13,16-17H2,1-2H3/b4-3+	CVKQUGPVDVFRAT-ONEGZZNKSA-N	50209685	CHEMBL226636::cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2A adrenergic receptor		 117								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209685&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44424855	104086409		CHEMBL226636				ZINC28654969	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50845610	COc1cc2NCC3C(CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H34N4O3/c1-19(13-20-7-5-4-6-8-20)17-30-9-11-31(12-10-30)18-26-22-16-28-23-15-25(33-3)24(32-2)14-21(23)27(22)29-34-26/h4-8,13-15,22,26,28H,9-12,16-18H2,1-3H3/b19-13+	JODRRUQCPGURFJ-CPNJWEJPSA-N	50209684	CHEMBL390718::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole	Alpha-2A adrenergic receptor		 2.4								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209684&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44424854	104086408		CHEMBL390718				ZINC28654956	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50872228	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor					 8.5					ChEMBL	10.1021/np058114h	10.7270/Q2V98907	16562853			Gafner, S; Dietz, BM; McPhail, KL; Scott, IM; Glinski, JA; Russell, FE; McCollom, MM; Budzinski, JW; Foster, BC; Bergeron, C; Rhyu, MR; Bolton, JL	Tom's of Maine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50858331	COc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc(OC)c1	InChI=1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)	VHKBTPQDHDSBSP-UHFFFAOYSA-N	50212239	5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide::A-803467::CHEMBL250699	Alpha-2A adrenergic receptor			>10000							ChEMBL	10.1073/pnas.0611364104	10.7270/Q2J10411	17483457			Jarvis, MF; Honore, P; Shieh, CC; Chapman, M; Joshi, S; Zhang, XF; Kort, M; Carroll, W; Marron, B; Atkinson, R; Thomas, J; Liu, D; Krambis, M; Liu, Y; McGaraughty, S; Chu, K; Roeloffs, R; Zhong, C; Mikusa, JP; Hernandez, G; Gauvin, D; Wade, C; Zhu, C; Pai, M; Scanio, M; Shi, L; Drizin, I; Gregg, R; Matulenko, M; Hakeem, A; Gross, M; Johnson, M; Marsh, K; Wagoner, PK; Sullivan, JP; Faltynek, CR; Krafte, DS	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212239&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	95T	7WFR,7WE4,7WEL	16038374	104088220		CHEMBL250699		5734		ZINC14982453	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869071	Cn1nccc1-c1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C16H16N4/c1-20-15(7-8-19-20)13-4-2-3-11-12(13)5-6-14(11)16-17-9-10-18-16/h2-4,7-10,14H,5-6H2,1H3,(H,17,18)	FYRLXCDBIMGTKV-UHFFFAOYSA-N	50377386	CHEMBL406348	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377386&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449723	160856469		CHEMBL406348				ZINC29048230	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869072	Cc1[nH]ncc1-c1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C16H16N4/c1-10-15(9-19-20-10)12-4-2-3-11-13(12)5-6-14(11)16-17-7-8-18-16/h2-4,7-9,14H,5-6H2,1H3,(H,17,18)(H,19,20)	MACSPWGTMJSVNZ-UHFFFAOYSA-N	50377387	CHEMBL260720	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377387&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449725	160856470		CHEMBL260720				ZINC29048240	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869073	C1Cc2c(cccc2-c2cn[nH]c2)C1c1ncc[nH]1	InChI=1S/C15H14N4/c1-2-11(10-8-18-19-9-10)13-4-5-14(12(13)3-1)15-16-6-7-17-15/h1-3,6-9,14H,4-5H2,(H,16,17)(H,18,19)	ZXQIPWRUBBPGML-UHFFFAOYSA-N	50377388	CHEMBL406316	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377388&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449730	160856471		CHEMBL406316				ZINC29048252	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869074	C1Cc2c(cccc2-c2cc[nH]n2)C1c1ncc[nH]1	InChI=1S/C15H14N4/c1-2-10-11(12(3-1)14-6-7-18-19-14)4-5-13(10)15-16-8-9-17-15/h1-3,6-9,13H,4-5H2,(H,16,17)(H,18,19)	VFOKHHLQWNICHU-UHFFFAOYSA-N	50377389	CHEMBL256983	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377389&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449245	160856472		CHEMBL256983				ZINC29046240	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869075	CS(=O)(=O)Nc1c(Cl)ccc2C(CCCc12)c1ncc[nH]1	InChI=1S/C14H16ClN3O2S/c1-21(19,20)18-13-10-3-2-4-11(14-16-7-8-17-14)9(10)5-6-12(13)15/h5-8,11,18H,2-4H2,1H3,(H,16,17)	IWGVFEQPKZLBMA-UHFFFAOYSA-N	50238839	CHEMBL256982::N-(2-chloro-5-(1H-imidazol-2-yl)-5,6,7,8-tetrahydronaphthalen-1-yl)methanesulfonamide::N-[2-Chloro-5-(1H-imidazol-2-yl)-5,6,7,8-tetrahydro-naphthalen-1-yl]-methanesulfonamide	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50238839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50238839&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25066019	104056495		CHEMBL256982				ZINC29046235	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869076	COc1c2CCC(c3ncc[nH]3)c2ccc1C	InChI=1S/C14H16N2O/c1-9-3-4-10-11(13(9)17-2)5-6-12(10)14-15-7-8-16-14/h3-4,7-8,12H,5-6H2,1-2H3,(H,15,16)	DHMOWBLMIPAURS-UHFFFAOYSA-N	50377390	CHEMBL256984	Alpha-2A adrenergic receptor					 327					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377390&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449247	160856473		CHEMBL256984				ZINC29046249	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869077	COc1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C13H14N2O/c1-16-12-4-2-3-9-10(12)5-6-11(9)13-14-7-8-15-13/h2-4,7-8,11H,5-6H2,1H3,(H,14,15)	IEVQENKCCRQYBX-UHFFFAOYSA-N	50377391	CHEMBL402388	Alpha-2A adrenergic receptor					 27					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377391&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449277	160856474		CHEMBL402388				ZINC29046382	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869078	CNC(=O)c1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C14H15N3O/c1-15-14(18)12-4-2-3-9-10(12)5-6-11(9)13-16-7-8-17-13/h2-4,7-8,11H,5-6H2,1H3,(H,15,18)(H,16,17)	SIMGMPZLDHYMNW-UHFFFAOYSA-N	50377392	CHEMBL257976	Alpha-2A adrenergic receptor					 4340					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377392&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449276	160856475		CHEMBL257976				ZINC29046379	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869079	CS(=O)(=O)Nc1cccc2C(CCCc12)c1ncc[nH]1	InChI=1S/C14H17N3O2S/c1-20(18,19)17-13-7-3-4-10-11(13)5-2-6-12(10)14-15-8-9-16-14/h3-4,7-9,12,17H,2,5-6H2,1H3,(H,15,16)	KATMPNHRKCPFCF-UHFFFAOYSA-N	50377393	CHEMBL257977	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377393&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449278	160856476		CHEMBL257977				ZINC29046387	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869080	CS(=O)(=O)Nc1cccc2C(CCCc12)c1ncc[nH]1	InChI=1S/C14H17N3O2S/c1-20(18,19)17-13-7-3-4-10-11(13)5-2-6-12(10)14-15-8-9-16-14/h3-4,7-9,12,17H,2,5-6H2,1H3,(H,15,16)	KATMPNHRKCPFCF-UHFFFAOYSA-N	50377393	CHEMBL257977	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377393&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449278	160856476		CHEMBL257977				ZINC29046387	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869081	CS(=O)(=O)Nc1cccc2C(CCCc12)c1ncc[nH]1	InChI=1S/C14H17N3O2S/c1-20(18,19)17-13-7-3-4-10-11(13)5-2-6-12(10)14-15-8-9-16-14/h3-4,7-9,12,17H,2,5-6H2,1H3,(H,15,16)	KATMPNHRKCPFCF-UHFFFAOYSA-N	50377393	CHEMBL257977	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377393&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449278	160856476		CHEMBL257977				ZINC29046387	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869082	CCS(=O)(=O)Nc1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C14H17N3O2S/c1-2-20(18,19)17-13-5-3-4-10-11(13)6-7-12(10)14-15-8-9-16-14/h3-5,8-9,12,17H,2,6-7H2,1H3,(H,15,16)	VHKRHCDBRNOWND-UHFFFAOYSA-N	50377394	CHEMBL404566	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377394&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449305	160856477		CHEMBL404566				ZINC29046494	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869083	CS(=O)(=O)Nc1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C13H15N3O2S/c1-19(17,18)16-12-4-2-3-9-10(12)5-6-11(9)13-14-7-8-15-13/h2-4,7-8,11,16H,5-6H2,1H3,(H,14,15)	QAFWYWHBAHTELS-UHFFFAOYSA-N	50377395	CHEMBL257800	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377395&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449304	160856478		CHEMBL257800				ZINC29046489	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869084	C1CC(c2ncc[nH]2)c2ccccc2C1	InChI=1S/C13H14N2/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13/h1-2,4,6,8-9,12H,3,5,7H2,(H,14,15)	BLXFHJKHZWXNDP-UHFFFAOYSA-N	50377396	CHEMBL258007	Alpha-2A adrenergic receptor					 722					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377396&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			17804479	160856479		CHEMBL258007				ZINC29046509	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869090	Clc1ccc2C(CCc2c1-c1cn[nH]c1)c1ncc[nH]1	InChI=1S/C15H13ClN4/c16-13-4-3-10-11(14(13)9-7-19-20-8-9)1-2-12(10)15-17-5-6-18-15/h3-8,12H,1-2H2,(H,17,18)(H,19,20)	JMAPPYYTLHLIJH-UHFFFAOYSA-N	50238834	2-(5-chloro-4-(1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole::4-(5-chloro-1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole::CHEMBL257799	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50238834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50238834&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449303	104056494		CHEMBL257799				ZINC29046483	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869124	Cc1c(OCC2=NCCN2)ccc(Cl)c1NS(C)(=O)=O	InChI=1S/C12H16ClN3O3S/c1-8-10(19-7-11-14-5-6-15-11)4-3-9(13)12(8)16-20(2,17)18/h3-4,16H,5-7H2,1-2H3,(H,14,15)	FOYWMEJSRSBQGB-UHFFFAOYSA-N	50377398	CHEMBL257978::Ro-115-1240	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377398&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			216249	160856481		CHEMBL257978				ZINC49952320	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869125	Cc1oncc1-c1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C16H15N3O/c1-10-15(9-19-20-10)12-4-2-3-11-13(12)5-6-14(11)16-17-7-8-18-16/h2-4,7-9,14H,5-6H2,1H3,(H,17,18)	XSJUZZWXFYDPDG-UHFFFAOYSA-N	50377399	CHEMBL260009	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377399&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449657	160856482		CHEMBL260009				ZINC29047998	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869126	C1Cc2c(cccc2-c2nccs2)C1c1ncc[nH]1	InChI=1S/C15H13N3S/c1-2-10-11(13(3-1)15-18-8-9-19-15)4-5-12(10)14-16-6-7-17-14/h1-3,6-9,12H,4-5H2,(H,16,17)	CDJSNQBVAYXVIN-UHFFFAOYSA-N	50377400	CHEMBL260116	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377400&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449686	160856483		CHEMBL260116				ZINC29048100	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869085	CCS(=O)(=O)Nc1cccc(Cc2cnc[nH]2)c1	InChI=1S/C12H15N3O2S/c1-2-18(16,17)15-11-5-3-4-10(6-11)7-12-8-13-9-14-12/h3-6,8-9,15H,2,7H2,1H3,(H,13,14)	ROUIPNDCVDWYEH-UHFFFAOYSA-N	50118705	ABT-866::CHEMBL326702::Ethanesulfonic acid [3-(1H-imidazol-4-ylmethyl)-phenyl]-amide::N-(3-((1H-imidazol-4-yl)methyl)phenyl)ethanesulfonamide::N-[3-(1H-imidazol-4-ylmethyl)-phenyl]ethanesulfonamide	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118705&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9838192	104011969		CHEMBL326702				ZINC00008784	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869131	C1Cc2c(cccc2-c2ncco2)C1c1ncc[nH]1	InChI=1S/C15H13N3O/c1-2-10-11(13(3-1)15-18-8-9-19-15)4-5-12(10)14-16-6-7-17-14/h1-3,6-9,12H,4-5H2,(H,16,17)	MWTDIAXAEKTMKO-UHFFFAOYSA-N	50377401	CHEMBL407308	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377401&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449692	160856484		CHEMBL407308				ZINC29048117	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869132	C1Cc2c(cccc2-c2cccnc2)C1c1ncc[nH]1	InChI=1S/C17H15N3/c1-4-13(12-3-2-8-18-11-12)15-6-7-16(14(15)5-1)17-19-9-10-20-17/h1-5,8-11,16H,6-7H2,(H,19,20)	DYDXENMSZODUFG-UHFFFAOYSA-N	50377402	CHEMBL260576	Alpha-2A adrenergic receptor					 4580					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377402&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449691	160856485		CHEMBL260576				ZINC29048111	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869133	C1Cc2c(cccc2-c2ccccn2)C1c1ncc[nH]1	InChI=1S/C17H15N3/c1-2-9-18-16(6-1)14-5-3-4-12-13(14)7-8-15(12)17-19-10-11-20-17/h1-6,9-11,15H,7-8H2,(H,19,20)	WOAORDZNFUQOSX-UHFFFAOYSA-N	50377403	CHEMBL260575	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377403&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449690	160856486		CHEMBL260575				ZINC29048106	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869134	Cn1ccc(n1)-c1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C16H16N4/c1-20-10-7-15(19-20)13-4-2-3-11-12(13)5-6-14(11)16-17-8-9-18-16/h2-4,7-10,14H,5-6H2,1H3,(H,17,18)	RDVMPVYUEVZOKC-UHFFFAOYSA-N	50377404	CHEMBL260789	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377404&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449694	160856487		CHEMBL260789				ZINC29048125	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869135	Cn1cc(cn1)-c1cccc2C(CCc12)c1ncc[nH]1	InChI=1S/C16H16N4/c1-20-10-11(9-19-20)12-3-2-4-13-14(12)5-6-15(13)16-17-7-8-18-16/h2-4,7-10,15H,5-6H2,1H3,(H,17,18)	RGODJQWSYIQDDR-UHFFFAOYSA-N	50377405	CHEMBL261304	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377405&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449724	160856488		CHEMBL261304				ZINC29048236	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50869169	Clc1ccc2C(CCc2c1-c1cc[nH]n1)c1ncc[nH]1	InChI=1S/C15H13ClN4/c16-12-4-3-9-10(14(12)13-5-6-19-20-13)1-2-11(9)15-17-7-8-18-15/h3-8,11H,1-2H2,(H,17,18)(H,19,20)	QFWHXAUYMHHEEF-UHFFFAOYSA-N	50377397	CHEMBL402003	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1016/j.bmcl.2008.03.070	10.7270/Q2VQ33KM	18400496			Whitlock, GA; Conlon, K; McMurray, G; Roberts, LR; Stobie, A; Thurlow, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377397&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44449337	160856480		CHEMBL402003				ZINC29046634	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50878766	CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12	InChI=1S/C24H26N2O2S/c1-17-14-20-8-10-21(16-24(20)23(17)12-13-26(2)3)25-29(27,28)22-11-9-18-6-4-5-7-19(18)15-22/h4-11,15-16,25H,12-14H2,1-3H3	JIKAKDQZRABPAQ-UHFFFAOYSA-N	50266555	CHEMBL457570::N-(3-(2-(dimethylamino)ethyl)-2-methyl-1H-inden-5-yl)naphthalene-2-sulfonamide	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1021/jm8009469	10.7270/Q2SN09V7	19159187			Alcalde, E; Mesquida, N; Lopez-Perez, S; Frigola, J; Merce, R	Universitat de Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266555&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16718827	104113874		CHEMBL457570				ZINC40847929	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50878768	CN(C)CCC1=C(C)Cc2ccc(cc12)S(=O)(=O)Nc1cccc2ccccc12	InChI=1S/C24H26N2O2S/c1-17-15-19-11-12-20(16-23(19)21(17)13-14-26(2)3)29(27,28)25-24-10-6-8-18-7-4-5-9-22(18)24/h4-12,16,25H,13-15H2,1-3H3	NCXJCTGPMJFTES-UHFFFAOYSA-N	50266639	3-(2-(dimethylamino)ethyl)-2-methyl-N-(naphthalen-1-yl)-1H-indene-5-sulfonamide::CHEMBL475969	Alpha-2A adrenergic receptor			 1097							ChEMBL	10.1021/jm8009469	10.7270/Q2SN09V7	19159187			Alcalde, E; Mesquida, N; Lopez-Perez, S; Frigola, J; Merce, R	Universitat de Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266639&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25208878	104113909		CHEMBL475969				ZINC40404576	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50878769	CN(C)CCC1=CCc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12	InChI=1S/C18H19ClN4O2S2/c1-22(2)8-7-13-4-3-12-5-6-14(11-15(12)13)21-27(24,25)17-16(19)20-18-23(17)9-10-26-18/h4-6,9-11,21H,3,7-8H2,1-2H3	YSMNKAMHMGKRDL-UHFFFAOYSA-N	34154	CHEMBL515307::indenylsulfonamide, 15	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1021/jm8009469	10.7270/Q2SN09V7	19159187			Alcalde, E; Mesquida, N; Lopez-Perez, S; Frigola, J; Merce, R	Universitat de Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34154&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16718920	85301162		CHEMBL515307				ZINC40918747	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50878770	CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12	InChI=1S/C19H21ClN4O2S2/c1-12-10-13-4-5-14(11-16(13)15(12)6-7-23(2)3)22-28(25,26)18-17(20)21-19-24(18)8-9-27-19/h4-5,8-9,11,22H,6-7,10H2,1-3H3	SLAAJLIHBBZSNF-UHFFFAOYSA-N	34153	CHEMBL476006::indenylsulfonamide, 14	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1021/jm8009469	10.7270/Q2SN09V7	19159187			Alcalde, E; Mesquida, N; Lopez-Perez, S; Frigola, J; Merce, R	Universitat de Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34153&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16112801	85301161		CHEMBL476006				ZINC35261422	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50878771	CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3csc4ccccc34)cc12	InChI=1S/C22H24N2O2S2/c1-15-12-16-8-9-17(13-20(16)18(15)10-11-24(2)3)23-28(25,26)22-14-27-21-7-5-4-6-19(21)22/h4-9,13-14,23H,10-12H2,1-3H3	XWXCMQFSARGQNK-UHFFFAOYSA-N	50266578	CHEMBL477650::N-{3-[2-(Dimethylamino)ethyl]-2-methyl-1H-inden-5-yl}-1-benzothiophene-3-sulfonamide	Alpha-2A adrenergic receptor			 700							ChEMBL	10.1021/jm8009469	10.7270/Q2SN09V7	19159187			Alcalde, E; Mesquida, N; Lopez-Perez, S; Frigola, J; Merce, R	Universitat de Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266578&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16718917	104113881		CHEMBL477650				ZINC40918942	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50917629	CCCCC1CCN(CCCC(=O)c2ccccc2C)CC1	InChI=1S/C20H31NO/c1-3-4-9-18-12-15-21(16-13-18)14-7-11-20(22)19-10-6-5-8-17(19)2/h5-6,8,10,18H,3-4,7,9,11-16H2,1-2H3	ANTKBACNWQHQJE-UHFFFAOYSA-N	50326219	4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one::CHEMBL1242950::CHEMBL2206334	Alpha-2A adrenergic receptor		 530								ChEMBL	10.1021/jm100697g	10.7270/Q2765G9K	20684563			Sams, AG; Hentzer, M; Mikkelsen, GK; Larsen, K; Bundgaard, C; Plath, N; Christoffersen, CT; Bang-Andersen, B	H. Lundbeck A/S	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326219&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9948320	123105334		CHEMBL2206334CHEMBL1242950		289		ZINC02022527	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50907235	COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23	InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	WSVWKHTVFGTTKJ-AWEZNQCLSA-N	50160160	(S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-9,11-dioxa-6-aza-benzo[fg]cyclopenta[b]anthracene::CHEMBL179440	Alpha-2A adrenergic receptor		 1288								ChEMBL	10.1016/j.bmcl.2009.11.053	10.7270/Q2C53MT3	19963380			Legendre, O; Pecic, S; Chaudhary, S; Zimmerman, SM; Fantegrossi, WE; Harding, WW	Hunter College and the Graduate Center of the City University of New York	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160160&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			197001	104046720	68992	CHEMBL179440				ZINC00338136	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50912764	C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(O)c4c(cc(O)cc4=O)oc3-c3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O	InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-30,32-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1	HRFGZDXDXWODFE-NVPNHPEKSA-N	50217942	2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside::3-Rhamnoglucosylquercetin::3-Rutinosyl quercetin::CHEMBL226335::cid_5280805::rutin	Alpha-2A adrenergic receptor		 9340								ChEMBL	10.1021/np1000329	10.7270/Q2H99642	20408551			Nahrstedt, A; Butterweck, V	Westfalische Wilhelms-Universitat	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217942&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	RUT	1RY8	5280805	104091802	28527	CHEMBL226335			C02757	ZINC04096846	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50921314	Fc1nc(cs1)C#Cc1cc(F)cc(c1)C#N	InChI=1S/C12H4F2N2S/c13-10-4-8(3-9(5-10)6-15)1-2-11-7-17-12(14)16-11/h3-5,7H	LVXAMCKZCLWWTF-UHFFFAOYSA-N	50336843	3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonitrile::CHEMBL1672288	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm101430m	10.7270/Q26Q1Z7T	21207959			Simeon, FG; Wendahl, MT; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336843&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			51050257	125086945		CHEMBL1672288				ZINC66078097	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50932742	Clc1ccc2Oc3ncccc3C(=Nc2c1)N1CCNCC1	InChI=1S/C16H15ClN4O/c17-11-3-4-14-13(10-11)20-15(21-8-6-18-7-9-21)12-2-1-5-19-16(12)22-14/h1-5,10,18H,6-9H2	ZCSQZBVTVLZRJN-UHFFFAOYSA-N	50382679	CHEMBL2022269	Alpha-2A adrenergic receptor		 729								ChEMBL	10.1021/jm2013419	10.7270/Q2R49RT3	22268448			Liegeois, JF; Deville, M; Dilly, S; Lamy, C; Mangin, F; Resimont, M; Tarazi, FI	University of Li&#163;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382679&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56964693	160861762		CHEMBL2022269				ZINC84635975	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50932743	Clc1ccc2Oc3ncccc3C(=Nc2c1)N1CCN(CCc2ccccc2)CC1	InChI=1S/C24H23ClN4O/c25-19-8-9-22-21(17-19)27-23(20-7-4-11-26-24(20)30-22)29-15-13-28(14-16-29)12-10-18-5-2-1-3-6-18/h1-9,11,17H,10,12-16H2	KMWUPPLGFWGMEM-UHFFFAOYSA-N	50382677	CHEMBL2022272	Alpha-2A adrenergic receptor		 374								ChEMBL	10.1021/jm2013419	10.7270/Q2R49RT3	22268448			Liegeois, JF; Deville, M; Dilly, S; Lamy, C; Mangin, F; Resimont, M; Tarazi, FI	University of Li&#163;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382677&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56964794	160861760		CHEMBL2022272				ZINC84635507	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50932744	Clc1ccc2Oc3ncccc3C(=Nc2c1)N1CCN(CC1)C1CCCCC1	InChI=1S/C22H25ClN4O/c23-16-8-9-20-19(15-16)25-21(18-7-4-10-24-22(18)28-20)27-13-11-26(12-14-27)17-5-2-1-3-6-17/h4,7-10,15,17H,1-3,5-6,11-14H2	VJUWCGANMBDVKL-UHFFFAOYSA-N	50382678	CHEMBL2022273	Alpha-2A adrenergic receptor		 412								ChEMBL	10.1021/jm2013419	10.7270/Q2R49RT3	22268448			Liegeois, JF; Deville, M; Dilly, S; Lamy, C; Mangin, F; Resimont, M; Tarazi, FI	University of Li&#163;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382678&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57326584	160861761		CHEMBL2022273				ZINC84635509	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50932745	OCCOCCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Oc2ncccc12	InChI=1S/C20H23ClN4O3/c21-15-3-4-18-17(14-15)23-19(16-2-1-5-22-20(16)28-18)25-8-6-24(7-9-25)10-12-27-13-11-26/h1-5,14,26H,6-13H2	GTVOJGQRQIZKFZ-UHFFFAOYSA-N	50382683	CHEMBL2022275	Alpha-2A adrenergic receptor		 452								ChEMBL	10.1021/jm2013419	10.7270/Q2R49RT3	22268448			Liegeois, JF; Deville, M; Dilly, S; Lamy, C; Mangin, F; Resimont, M; Tarazi, FI	University of Li&#163;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382683&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57326586	160861766		CHEMBL2022275				ZINC84619133	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50932746	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Oc2ncccc12	InChI=1S/C17H17ClN4O/c1-21-7-9-22(10-8-21)16-13-3-2-6-19-17(13)23-15-5-4-12(18)11-14(15)20-16/h2-6,11H,7-10H2,1H3	XUSZOVSAUPFWTP-UHFFFAOYSA-N	50382674	CHEMBL147463::CHEMBL2022280	Alpha-2A adrenergic receptor		 180								ChEMBL	10.1021/jm2013419	10.7270/Q2R49RT3	22268448			Liegeois, JF; Deville, M; Dilly, S; Lamy, C; Mangin, F; Resimont, M; Tarazi, FI	University of Li&#163;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382674&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			188249	160861757		CHEMBL2022280CHEMBL147463				ZINC27560709	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50932747	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	QZUDBNBUXVUHMW-UHFFFAOYSA-N	50001884	2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine	Alpha-2A adrenergic receptor		 185								ChEMBL	10.1021/jm2013419	10.7270/Q2R49RT3	22268448			Liegeois, JF; Deville, M; Dilly, S; Lamy, C; Mangin, F; Resimont, M; Tarazi, FI	University of Li&#163;ge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	103916251	3766	CHEMBL42CHEMBL538973	DB00363	38	C06924	ZINC19796155	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50933842	C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(F)cc1	InChI=1S/C22H22FNO2/c1-15-3-2-11-24(15)12-10-20-14-18-13-17(6-9-21(18)26-20)22(25)16-4-7-19(23)8-5-16/h4-9,13-15H,2-3,10-12H2,1H3/t15-/m1/s1	VGSYEFOBFMUWGO-OAHLLOKOSA-N	50158610	(4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-methanone::CHEMBL555146	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm201690h	10.7270/Q2BR8T6Z	22313227			Bao, X; Lu, S; Liow, JS; Zoghbi, SS; Jenko, KJ; Clark, DT; Gladding, RL; Innis, RB; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158610&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9906447	104045289		CHEMBL555146				ZINC03818810	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50933843	C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C22H22N2O4/c1-15-3-2-11-23(15)12-10-20-14-18-13-17(6-9-21(18)28-20)22(25)16-4-7-19(8-5-16)24(26)27/h4-9,13-15H,2-3,10-12H2,1H3/t15-/m1/s1	GPZMWOXSIRVXQW-OAHLLOKOSA-N	50383117	CHEMBL2031737	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/jm201690h	10.7270/Q2BR8T6Z	22313227			Bao, X; Lu, S; Liow, JS; Zoghbi, SS; Jenko, KJ; Clark, DT; Gladding, RL; Innis, RB; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383117&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56963799	160862200		CHEMBL2031737				ZINC84759385	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50923763	CO[C@H]1Cc2c(cnn2-c2ccccc2)C2(CCN(Cc3ccccc3)CC2)O1	InChI=1S/C24H27N3O2/c1-28-23-16-22-21(17-25-27(22)20-10-6-3-7-11-20)24(29-23)12-14-26(15-13-24)18-19-8-4-2-5-9-19/h2-11,17,23H,12-16,18H2,1H3/t23-/m1/s1	HYVLLMHHSJIFSU-HSZRJFAPSA-N	50321778	(R)-1-benzyl-6'-methoxy-1'-phenyl-6',7'-dihydro-1'H-spiro[piperidine-4,4'-pyrano[4,3-c]pyrazole]::CHEMBL1169777	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1021/jm200585k	10.7270/Q22R3SN0	21859078			Schlager, T; Schepmann, D; Lehmkuhl, K; Holenz, J; Vela, JM; Buschmann, H; Wunsch, B	Institut f&#163;r Pharmazeutische und Medizinische Chemie der Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321778&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49798691	104143307		CHEMBL1169777				ZINC53294046	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50923764	COC1Cc2c(cnn2-c2ccccc2)C2(CCN(CC3CCCCC3)CC2)O1	InChI=1S/C24H33N3O2/c1-28-23-16-22-21(17-25-27(22)20-10-6-3-7-11-20)24(29-23)12-14-26(15-13-24)18-19-8-4-2-5-9-19/h3,6-7,10-11,17,19,23H,2,4-5,8-9,12-16,18H2,1H3	VXFHKYALKRURJZ-UHFFFAOYSA-N	50353612	CHEMBL1829574	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1021/jm200585k	10.7270/Q22R3SN0	21859078			Schlager, T; Schepmann, D; Lehmkuhl, K; Holenz, J; Vela, JM; Buschmann, H; Wunsch, B	Institut f&#163;r Pharmazeutische und Medizinische Chemie der Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353612&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25060024	136360298		CHEMBL1829574				ZINC72116462	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50923765	CO[C@H]1Cc2c(cnn2-c2ccccc2)C2(CCN(CC(C)C)CC2)O1	InChI=1S/C21H29N3O2/c1-16(2)15-23-11-9-21(10-12-23)18-14-22-24(17-7-5-4-6-8-17)19(18)13-20(25-3)26-21/h4-8,14,16,20H,9-13,15H2,1-3H3/t20-/m1/s1	UZYLFJRNQUYFQY-HXUWFJFHSA-N	50321779	(R)-1-isobutyl-6'-methoxy-1'-phenyl-6',7'-dihydro-1'H-spiro[piperidine-4,4'-pyrano[4,3-c]pyrazole]::CHEMBL1170769	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1021/jm200585k	10.7270/Q22R3SN0	21859078			Schlager, T; Schepmann, D; Lehmkuhl, K; Holenz, J; Vela, JM; Buschmann, H; Wunsch, B	Institut f&#163;r Pharmazeutische und Medizinische Chemie der Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321779&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49798692	104143308		CHEMBL1170769				ZINC53293627	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50923766	COC1Cc2c(cnn2-c2ccccc2)C2(CCN(CCC(C)C)CC2)O1	InChI=1S/C22H31N3O2/c1-17(2)9-12-24-13-10-22(11-14-24)19-16-23-25(18-7-5-4-6-8-18)20(19)15-21(26-3)27-22/h4-8,16-17,21H,9-15H2,1-3H3	XHRYSFFNMRUMRJ-UHFFFAOYSA-N	50353615	CHEMBL1829580	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1021/jm200585k	10.7270/Q22R3SN0	21859078			Schlager, T; Schepmann, D; Lehmkuhl, K; Holenz, J; Vela, JM; Buschmann, H; Wunsch, B	Institut f&#163;r Pharmazeutische und Medizinische Chemie der Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353615&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25060021	136360301		CHEMBL1829580				ZINC72116667	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50923767	CCCCCCCCN1CCC2(CC1)OC(Cc1c2cnn1-c1ccccc1)OC	InChI=1S/C25H37N3O2/c1-3-4-5-6-7-11-16-27-17-14-25(15-18-27)22-20-26-28(21-12-9-8-10-13-21)23(22)19-24(29-2)30-25/h8-10,12-13,20,24H,3-7,11,14-19H2,1-2H3	KAOJXFGRVRYMTH-UHFFFAOYSA-N	50353617	CHEMBL1829659	Alpha-2A adrenergic receptor			>1000							ChEMBL	10.1021/jm200585k	10.7270/Q22R3SN0	21859078			Schlager, T; Schepmann, D; Lehmkuhl, K; Holenz, J; Vela, JM; Buschmann, H; Wunsch, B	Institut f&#163;r Pharmazeutische und Medizinische Chemie der Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353617&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25060023	136360303		CHEMBL1829659				ZINC72118306	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50933978	O=C(NC1CCCC1)c1ccc(cc1)-c1ccc2C(=O)N(CCN3CCCC3)CCc2c1	InChI=1S/C27H33N3O2/c31-26(28-24-5-1-2-6-24)21-9-7-20(8-10-21)22-11-12-25-23(19-22)13-16-30(27(25)32)18-17-29-14-3-4-15-29/h7-12,19,24H,1-6,13-18H2,(H,28,31)	WZHAQWFZACLGKI-UHFFFAOYSA-N	50383152	CHEMBL2031873	Alpha-2A adrenergic receptor		>3000								ChEMBL	10.1021/jm300011d	10.7270/Q2736RZR	22313242			Zhou, D; Gross, JL; Adedoyin, AB; Aschmies, SB; Brennan, J; Bowlby, M; Di, L; Kubek, K; Platt, BJ; Wang, Z; Zhang, G; Brandon, N; Comery, TA; Robichaud, AJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383152&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218143	160862235		CHEMBL2031873				ZINC59114247	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50933979	CN(C)C(=O)c1ccc(cc1)-c1ccc2C(=O)N(CCN3CCCC3)CCc2c1	InChI=1S/C24H29N3O2/c1-25(2)23(28)19-7-5-18(6-8-19)20-9-10-22-21(17-20)11-14-27(24(22)29)16-15-26-12-3-4-13-26/h5-10,17H,3-4,11-16H2,1-2H3	VEGKMRUZYWQMBZ-UHFFFAOYSA-N	50383153	CHEMBL2031874	Alpha-2A adrenergic receptor		>3000								ChEMBL	10.1021/jm300011d	10.7270/Q2736RZR	22313242			Zhou, D; Gross, JL; Adedoyin, AB; Aschmies, SB; Brennan, J; Bowlby, M; Di, L; Kubek, K; Platt, BJ; Wang, Z; Zhang, G; Brandon, N; Comery, TA; Robichaud, AJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383153&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218397	160862236		CHEMBL2031874				ZINC59114791	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50933980	C[C@@H]1CCCN1C(=O)c1ccc(cc1)-c1ccc2C(=O)N(CCN3CCCC3)CCc2c1	InChI=1S/C27H33N3O2/c1-20-5-4-15-30(20)26(31)22-8-6-21(7-9-22)23-10-11-25-24(19-23)12-16-29(27(25)32)18-17-28-13-2-3-14-28/h6-11,19-20H,2-5,12-18H2,1H3/t20-/m1/s1	QKNQLRSRULGFBA-HXUWFJFHSA-N	50383155	CHEMBL2031876	Alpha-2A adrenergic receptor		>3000								ChEMBL	10.1021/jm300011d	10.7270/Q2736RZR	22313242			Zhou, D; Gross, JL; Adedoyin, AB; Aschmies, SB; Brennan, J; Bowlby, M; Di, L; Kubek, K; Platt, BJ; Wang, Z; Zhang, G; Brandon, N; Comery, TA; Robichaud, AJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383155	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383155&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68731121	160862238		CHEMBL2031876				ZINC84653049	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50933981	C[C@H]1CCCN1C(=O)c1ccc(cc1)-c1ccc2C(=O)N(CCN3CCCC3)CCc2c1	InChI=1S/C27H33N3O2/c1-20-5-4-15-30(20)26(31)22-8-6-21(7-9-22)23-10-11-25-24(19-23)12-16-29(27(25)32)18-17-28-13-2-3-14-28/h6-11,19-20H,2-5,12-18H2,1H3/t20-/m0/s1	QKNQLRSRULGFBA-FQEVSTJZSA-N	50383156	CHEMBL2031877	Alpha-2A adrenergic receptor		>3000								ChEMBL	10.1021/jm300011d	10.7270/Q2736RZR	22313242			Zhou, D; Gross, JL; Adedoyin, AB; Aschmies, SB; Brennan, J; Bowlby, M; Di, L; Kubek, K; Platt, BJ; Wang, Z; Zhang, G; Brandon, N; Comery, TA; Robichaud, AJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383156	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383156&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			69082816	160862239		CHEMBL2031877				ZINC84653050	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50933982	CCNC(=O)c1ccc(cc1)-c1ccc2C(=O)N(CCN3CCC[C@H]3C)CCc2c1	InChI=1S/C25H31N3O2/c1-3-26-24(29)20-8-6-19(7-9-20)21-10-11-23-22(17-21)12-14-28(25(23)30)16-15-27-13-4-5-18(27)2/h6-11,17-18H,3-5,12-16H2,1-2H3,(H,26,29)/t18-/m1/s1	LBAKRWRQQGNMEB-GOSISDBHSA-N	50383162	CHEMBL2031884	Alpha-2A adrenergic receptor		>3000								ChEMBL	10.1021/jm300011d	10.7270/Q2736RZR	22313242			Zhou, D; Gross, JL; Adedoyin, AB; Aschmies, SB; Brennan, J; Bowlby, M; Di, L; Kubek, K; Platt, BJ; Wang, Z; Zhang, G; Brandon, N; Comery, TA; Robichaud, AJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383162&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25216680	160862245		CHEMBL2031884				ZINC59111730	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50933983	C[C@@H]1CCCN1CCN1CCc2cc(ccc2C1=O)-c1ccc(cc1)C(=O)N1CCCC1	InChI=1S/C27H33N3O2/c1-20-5-4-15-28(20)17-18-30-16-12-24-19-23(10-11-25(24)27(30)32)21-6-8-22(9-7-21)26(31)29-13-2-3-14-29/h6-11,19-20H,2-5,12-18H2,1H3/t20-/m1/s1	SPKOQCHHYOCMGR-HXUWFJFHSA-N	50383163	CHEMBL2031885	Alpha-2A adrenergic receptor		>3000								ChEMBL	10.1021/jm300011d	10.7270/Q2736RZR	22313242			Zhou, D; Gross, JL; Adedoyin, AB; Aschmies, SB; Brennan, J; Bowlby, M; Di, L; Kubek, K; Platt, BJ; Wang, Z; Zhang, G; Brandon, N; Comery, TA; Robichaud, AJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383163&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25218401	160862246		CHEMBL2031885				ZINC59114798	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50934784	C[C@@H]1[C@H]2CN(CCC3(CCCCC3)C(O)=O)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F	InChI=1S/C26H33F3N2O2/c1-16-20-15-31(12-10-25(24(32)33)8-3-2-4-9-25)11-7-17(20)13-22-23(16)19-14-18(26(27,28)29)5-6-21(19)30-22/h5-6,14,16-17,20,30H,2-4,7-13,15H2,1H3,(H,32,33)/t16-,17-,20-/m1/s1	WAOZNBXSEVIAGX-MBOZVWFJSA-N	50383522	CHEMBL2032049	Alpha-2A adrenergic receptor		>2000								ChEMBL	10.1016/j.bmcl.2012.04.006	10.7270/Q2542PMN	22542010			Mihalic, JT; Fan, P; Chen, X; Chen, X; Fu, Y; Motani, A; Liang, L; Lindstrom, M; Tang, L; Chen, JL; Jaen, J; Dai, K; Li, L	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383522&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10004545	160862605		CHEMBL2032049				ZINC34074273	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50945450	CC1CNC(N1)=Nc1c(Cl)cccc1Cl	InChI=1S/C10H11Cl2N3/c1-6-5-13-10(14-6)15-9-7(11)3-2-4-8(9)12/h2-4,6H,5H2,1H3,(H2,13,14,15)	ITKQNORKNISIMB-UHFFFAOYSA-N	50387823	CHEMBL2058631	Alpha-2A adrenergic receptor		 1950								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387823&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12699315	160866906		CHEMBL2058631				ZINC28240471	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50945451	C1CC1C(NC1=[NH+]CCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)/p+1	CQXADFVORZEARL-UHFFFAOYSA-O	50262235	rilmenidine	Alpha-2A adrenergic receptor		 36								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262235&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44577959	104110975					C11120	ZINC00009708	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50945452	CC1COC(N1)=NC(C1CC1)C1CC1	InChI=1S/C11H18N2O/c1-7-6-14-11(12-7)13-10(8-2-3-8)9-4-5-9/h7-10H,2-6H2,1H3,(H,12,13)	PNHRXBTZWMJDSC-UHFFFAOYSA-N	50387824	CHEMBL2058632	Alpha-2A adrenergic receptor		 4898								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387824&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70696790	160866907		CHEMBL2058632				ZINC84671926	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50945453	Clc1ccccc1N=C1CCCN1	InChI=1S/C10H11ClN2/c11-8-4-1-2-5-9(8)13-10-6-3-7-12-10/h1-2,4-5H,3,6-7H2,(H,12,13)	DADXHMUZIXRGOH-UHFFFAOYSA-N	50387825	CHEMBL2058633	Alpha-2A adrenergic receptor		 3020								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387825&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			7059292	160866908		CHEMBL2058633				ZINC03866613	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50945454	CC1CCC(N1)=Nc1ccccc1Cl	InChI=1S/C11H13ClN2/c1-8-6-7-11(13-8)14-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	HPOVQRXZQJTUKW-UHFFFAOYSA-N	50387826	CHEMBL2058634	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387826&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70686398	160866909		CHEMBL2058634				ZINC84707280	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50945474	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 8.7								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50945475	CC1CCC(N1)=Nc1ccc(I)cc1Cl	InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	KLIBTBNNCGHLPY-UHFFFAOYSA-N	50387827	CHEMBL2058635	Alpha-2A adrenergic receptor		 2570								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387827&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10042547	160866910		CHEMBL2058635				ZINC67980450	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984729	Cc1nc2ccccn2c(=O)c1CCCN1CCc2oc3ccccc3c2C1	InChI=1S/C23H23N3O2/c1-16-17(23(27)26-13-5-4-10-22(26)24-16)8-6-12-25-14-11-21-19(15-25)18-7-2-3-9-20(18)28-21/h2-5,7,9-10,13H,6,8,11-12,14-15H2,1H3	KKLYBLFGKSXYJZ-UHFFFAOYSA-N	50403737	CHEMBL165776	Alpha-2A adrenergic receptor			 10							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403737&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376936	163352761		CHEMBL165776				ZINC27869119	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984732	Cc1nc2c(Cl)cc(Cl)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H19Cl2N3O2/c1-13-15(22(28)27-11-14(23)10-18(24)21(27)25-13)6-8-26-9-7-20-17(12-26)16-4-2-3-5-19(16)29-20/h2-5,10-11H,6-9,12H2,1H3	AKZOIEBLVQLVTR-UHFFFAOYSA-N	50403739	CHEMBL163247	Alpha-2A adrenergic receptor			 0.588844							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403739&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376993	163352763		CHEMBL163247				ZINC27856891	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984733	Cc1nc2ccc(Br)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H20BrN3O2/c1-14-16(22(27)26-12-15(23)6-7-21(26)24-14)8-10-25-11-9-20-18(13-25)17-4-2-3-5-19(17)28-20/h2-7,12H,8-11,13H2,1H3	BRKWIMBSEICBCU-UHFFFAOYSA-N	50403740	CHEMBL165350	Alpha-2A adrenergic receptor			 0.354813							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403740&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377200	163352764		CHEMBL165350				ZINC27859028	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984737	Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3ccc(Cl)cc3c2C1	InChI=1S/C22H20ClN3O2/c1-14-16(22(27)26-9-3-2-4-21(26)24-14)7-10-25-11-8-20-18(13-25)17-12-15(23)5-6-19(17)28-20/h2-6,9,12H,7-8,10-11,13H2,1H3	RJGDAIXCXQIWEK-UHFFFAOYSA-N	50403741	CHEMBL165677	Alpha-2A adrenergic receptor			 3.9							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403741	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403741&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377006	163352765		CHEMBL165677				ZINC27861658	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984744	Cc1cc(C)n2c(c1)nc(C)c(CCN1CCc3oc4ccccc4c3C1)c2=O	InChI=1S/C24H25N3O2/c1-15-12-16(2)27-23(13-15)25-17(3)18(24(27)28)8-10-26-11-9-22-20(14-26)19-6-4-5-7-21(19)29-22/h4-7,12-13H,8-11,14H2,1-3H3	GICQFAWDMCTLDM-UHFFFAOYSA-N	50403748	CHEMBL162232	Alpha-2A adrenergic receptor			 0.338844							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403748	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403748&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376954	163352772		CHEMBL162232				ZINC27858298	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984746	Cc1nc2c(C)cccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C23H23N3O2/c1-15-6-5-11-26-22(15)24-16(2)17(23(26)27)9-12-25-13-10-21-19(14-25)18-7-3-4-8-20(18)28-21/h3-8,11H,9-10,12-14H2,1-2H3	WLWNODXEXGTHDO-UHFFFAOYSA-N	50403750	CHEMBL351200	Alpha-2A adrenergic receptor			 0.602560							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403750&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377035	163352774		CHEMBL351200				ZINC27864607	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984748	O=c1c(CCN2CCc3oc4ccccc4c3C2)c(Cc2ccccc2)nc2ccccn12	InChI=1S/C28H25N3O2/c32-28-22(13-16-30-17-14-26-23(19-30)21-10-4-5-11-25(21)33-26)24(18-20-8-2-1-3-9-20)29-27-12-6-7-15-31(27)28/h1-12,15H,13-14,16-19H2	WGLYZLZIIJTKAG-UHFFFAOYSA-N	50403751	CHEMBL162436	Alpha-2A adrenergic receptor			 2.2							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403751&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376975	163352775		CHEMBL162436				ZINC27856272	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984752	Cc1ccc2nc(C)c(CCN3CCc4oc5ccccc5c4C3)c(=O)n2c1	InChI=1S/C23H23N3O2/c1-15-7-8-22-24-16(2)17(23(27)26(22)13-15)9-11-25-12-10-21-19(14-25)18-5-3-4-6-20(18)28-21/h3-8,13H,9-12,14H2,1-2H3	FPQNWBCHCMEAKI-UHFFFAOYSA-N	50403752	CHEMBL162370	Alpha-2A adrenergic receptor			 0.346737							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403752&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			22120322	163352776		CHEMBL162370				ZINC01903957	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984754	Cc1ccn2c(c1)nc(C)c(CCN1CCc3oc4ccccc4c3C1)c2=O	InChI=1S/C23H23N3O2/c1-15-7-12-26-22(13-15)24-16(2)17(23(26)27)8-10-25-11-9-21-19(14-25)18-5-3-4-6-20(18)28-21/h3-7,12-13H,8-11,14H2,1-2H3	FGTWZUQEDNXLLZ-UHFFFAOYSA-N	50403742	CHEMBL165796	Alpha-2A adrenergic receptor			 0.446684							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403742&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376958	163352766		CHEMBL165796				ZINC27862731	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984755	COc1cccn2c1nc(C)c(CCN1CCc3oc4ccccc4c3C1)c2=O	InChI=1S/C23H23N3O3/c1-15-16(23(27)26-11-5-8-21(28-2)22(26)24-15)9-12-25-13-10-20-18(14-25)17-6-3-4-7-19(17)29-20/h3-8,11H,9-10,12-14H2,1-2H3	HPNSJGWCFMHOJX-UHFFFAOYSA-N	50403745	CHEMBL162490	Alpha-2A adrenergic receptor			 0.295121							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403745&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			22120332	163352769		CHEMBL162490				ZINC27849549	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984758	Cc1nc2ccc(I)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H20IN3O2/c1-14-16(22(27)26-12-15(23)6-7-21(26)24-14)8-10-25-11-9-20-18(13-25)17-4-2-3-5-19(17)28-20/h2-7,12H,8-11,13H2,1H3	RTXNZOCMRSFEID-UHFFFAOYSA-N	50403753	CHEMBL162682	Alpha-2A adrenergic receptor			 0.239883							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403753	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403753&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376984	163352777		CHEMBL162682				ZINC27850209	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984773	Cc1nc2ccc(Cl)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H20ClN3O2/c1-14-16(22(27)26-12-15(23)6-7-21(26)24-14)8-10-25-11-9-20-18(13-25)17-4-2-3-5-19(17)28-20/h2-7,12H,8-11,13H2,1H3	GZFYZEHGCPEJAC-UHFFFAOYSA-N	50403738	CHEMBL351483	Alpha-2A adrenergic receptor			 0.213796							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403738&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377036	163352762		CHEMBL351483				ZINC27865233	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984775	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2A adrenergic receptor			 8.3							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984784	Cc1nc2cccc(C)n2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C23H23N3O2/c1-15-6-5-9-22-24-16(2)17(23(27)26(15)22)10-12-25-13-11-21-19(14-25)18-7-3-4-8-20(18)28-21/h3-9H,10-14H2,1-2H3	PUJAGVRPJZNJPF-UHFFFAOYSA-N	50403755	CHEMBL163190	Alpha-2A adrenergic receptor			 0.288403							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403755&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376923	163352779		CHEMBL163190				ZINC27855924	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984787	COc1cc2nc(C)c(CCN3CCc4oc5ccccc5c4C3)c(=O)n2cc1OC	InChI=1S/C24H25N3O4/c1-15-16(24(28)27-14-22(30-3)21(29-2)12-23(27)25-15)8-10-26-11-9-20-18(13-26)17-6-4-5-7-19(17)31-20/h4-7,12,14H,8-11,13H2,1-3H3	MBPZQLMDDBIIGZ-UHFFFAOYSA-N	50403743	CHEMBL162058	Alpha-2A adrenergic receptor			 3.5							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403743	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403743&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376845	163352767		CHEMBL162058				ZINC27854972	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984791	Cc1nc2c(O)cccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H21N3O3/c1-14-15(22(27)25-10-4-6-18(26)21(25)23-14)8-11-24-12-9-20-17(13-24)16-5-2-3-7-19(16)28-20/h2-7,10,26H,8-9,11-13H2,1H3	UDURNHDRCUMUOV-UHFFFAOYSA-N	50403747	CHEMBL162826	Alpha-2A adrenergic receptor			 0.691831							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403747&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376900	163352771		CHEMBL162826				ZINC27848632	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984798	Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H21N3O2/c1-15-16(22(26)25-11-5-4-8-21(25)23-15)9-12-24-13-10-20-18(14-24)17-6-2-3-7-19(17)27-20/h2-8,11H,9-10,12-14H2,1H3	ZYXHQIPQIKTEDI-UHFFFAOYSA-N	50403744	LUSAPERIDONE	Alpha-2A adrenergic receptor			 0.549541							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403744	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403744&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3045401	163352768						ZINC01903948	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984802	CN1CCN2C(C1)c1ccccc1Cc1cccnc21	InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3	RONZAEMNMFQXRA-UHFFFAOYSA-N	50115644	(+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON	Alpha-2A adrenergic receptor			 85							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115644&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4205	104009532	6950	CHEMBL654	DB00370	7241	C07570	ZINC19702119	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984806	Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3c(Cl)cccc3c2C1	InChI=1S/C22H20ClN3O2/c1-14-15(22(27)26-10-3-2-7-20(26)24-14)8-11-25-12-9-19-17(13-25)16-5-4-6-18(23)21(16)28-19/h2-7,10H,8-9,11-13H2,1H3	HNRZWHPQDGUUSO-UHFFFAOYSA-N	50403754	CHEMBL164612	Alpha-2A adrenergic receptor			 0.891251							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403754&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377007	163352778		CHEMBL164612				ZINC27862211	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984807	Cc1nc2ccccn2c(=O)c1CCN1CCc2sc3ccccc3c2C1	InChI=1S/C22H21N3OS/c1-15-16(22(26)25-11-5-4-8-21(25)23-15)9-12-24-13-10-20-18(14-24)17-6-2-3-7-19(17)27-20/h2-8,11H,9-10,12-14H2,1H3	JMXRRARDLWHYJN-UHFFFAOYSA-N	50403749	CHEMBL165181	Alpha-2A adrenergic receptor			 1.7							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403749	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403749&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9951544	163352773		CHEMBL165181				ZINC00588307	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50984777	Cc1nc2c(Cl)cc(cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1)C(F)(F)F	InChI=1S/C23H19ClF3N3O2/c1-13-15(22(31)30-11-14(23(25,26)27)10-18(24)21(30)28-13)6-8-29-9-7-20-17(12-29)16-4-2-3-5-19(16)32-20/h2-5,10-11H,6-9,12H2,1H3	JRMVEEDZCPVFFK-UHFFFAOYSA-N	50403746	CHEMBL162147	Alpha-2A adrenergic receptor			 1.2							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403746	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403746&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376927	163352770		CHEMBL162147				ZINC27855969	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50979965	Cc1c(oc2ccccc12)C(=O)N(CCCN1CCCCC1)c1ccccc1	InChI=1S/C24H28N2O2/c1-19-21-13-6-7-14-22(21)28-23(19)24(27)26(20-11-4-2-5-12-20)18-10-17-25-15-8-3-9-16-25/h2,4-7,11-14H,3,8-10,15-18H2,1H3	CTMDNCSJPPQMLF-UHFFFAOYSA-N	50401675	CHEMBL2205361	Alpha-2A adrenergic receptor		 1232								ChEMBL	10.1016/j.bmc.2012.09.044	10.7270/Q2833T6W	23084435			Marriott, KS; Morrison, AZ; Moore, M; Olubajo, O; Stewart, LE	Savannah State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401675&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71452341	163350699		CHEMBL2205361				ZINC95558674	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50979966	COc1cc2oc(C(=O)N(CCCN3CCCCC3)c3ccccc3)c(C)c2cc1OC	InChI=1S/C26H32N2O4/c1-19-21-17-23(30-2)24(31-3)18-22(21)32-25(19)26(29)28(20-11-6-4-7-12-20)16-10-15-27-13-8-5-9-14-27/h4,6-7,11-12,17-18H,5,8-10,13-16H2,1-3H3	RQJPWNOKFLOHKI-UHFFFAOYSA-N	50401674	CHEMBL2205362	Alpha-2A adrenergic receptor		 945								ChEMBL	10.1016/j.bmc.2012.09.044	10.7270/Q2833T6W	23084435			Marriott, KS; Morrison, AZ; Moore, M; Olubajo, O; Stewart, LE	Savannah State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401674&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71463022	163350698		CHEMBL2205362				ZINC95563125	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50979968	COc1ccc2c(C)c(oc2c1)C(=O)N(CCCN1CCCCC1)c1ccccc1	InChI=1S/C25H30N2O3/c1-19-22-13-12-21(29-2)18-23(22)30-24(19)25(28)27(20-10-5-3-6-11-20)17-9-16-26-14-7-4-8-15-26/h3,5-6,10-13,18H,4,7-9,14-17H2,1-2H3	UGKUXKJKFRZEQP-UHFFFAOYSA-N	50401673	CHEMBL2205360	Alpha-2A adrenergic receptor		 653								ChEMBL	10.1016/j.bmc.2012.09.044	10.7270/Q2833T6W	23084435			Marriott, KS; Morrison, AZ; Moore, M; Olubajo, O; Stewart, LE	Savannah State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401673&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71459553	163350697		CHEMBL2205360				ZINC95561089	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50979148	COc1ccccc1CCN1C2C3C4C5C3C1(O)C1C5CC4C21	InChI=1S/C20H23NO2/c1-23-12-5-3-2-4-9(12)6-7-21-19-15-10-8-11-14-13(10)16(19)18(14)20(21,22)17(11)15/h2-5,10-11,13-19,22H,6-8H2,1H3	PSBBAGWMKGXQRW-UHFFFAOYSA-N	50401362	CHEMBL2205836	Alpha-2A adrenergic receptor		 1301								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401362&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71450550	163350386		CHEMBL2205836					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985660	CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	SWGWJQBPCJEQJC-UHFFFAOYSA-N	50403957	CHEMBL313189	Alpha-2A adrenergic receptor			<1000							ChEMBL	10.1016/s0960-894x(01)00721-1	10.7270/Q23J3F4C	11755364			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403957&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44461606	163352981		CHEMBL313189				ZINC13436833	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50979232	CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O	InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)	BTJHDQFIFDTGOW-UHFFFAOYSA-N	50401403	CHEMBL2207493	Alpha-2A adrenergic receptor		 17170								ChEMBL	10.1021/jm300975f	10.7270/Q26974RR	23043306			Mattsson, C; Andreasson, T; Waters, N; Sonesson, C	NeuroSearch Sweden AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401403&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71454275	163350427		CHEMBL2207493				ZINC95563219	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985698	CNCC1CC2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2O/c1-19-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)20(18)21-15/h2-9,15,18-19H,10-12H2,1H3	LCKBEOTXTNWYRG-UHFFFAOYSA-N	50403962	CHEMBL81485	Alpha-2A adrenergic receptor			 437							ChEMBL	10.1016/s0960-894x(01)00721-1	10.7270/Q23J3F4C	11755364			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403962	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403962&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			19426635	163352986		CHEMBL81485				ZINC13436895	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985706	Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H	YNPFMWCWRVTGKJ-UHFFFAOYSA-N	31005	2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551	Alpha-2A adrenergic receptor			 21							ChEMBL	10.1016/s0960-894x(01)00721-1	10.7270/Q23J3F4C	11755364			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68551	242052839						ZINC00000504	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985748	CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1	BTSCZNWXJQSJIE-QFBILLFUSA-N	50146360	CHEMBL328573::Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine	Alpha-2A adrenergic receptor			 372							ChEMBL	10.1016/s0960-894x(01)00721-1	10.7270/Q23J3F4C	11755364			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146360&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9839081	104034979		CHEMBL328573				ZINC13436820	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985774	CN(C)CC1CC2N(O1)c1cc(F)ccc1Cc1ccc(F)cc21	InChI=1S/C19H20F2N2O/c1-22(2)11-16-10-19-17-8-14(20)5-3-12(17)7-13-4-6-15(21)9-18(13)23(19)24-16/h3-6,8-9,16,19H,7,10-11H2,1-2H3	GEDGEGJCGBTAON-UHFFFAOYSA-N	50403976	CHEMBL314107	Alpha-2A adrenergic receptor			<1000							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403976&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10246054	163353000		CHEMBL314107				ZINC13437214	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985824	CN(C)CC1CC2N(O1)c1cc(F)ccc1Cc1ccccc21	InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3	MSQRTETUBFIHMP-UHFFFAOYSA-N	50403974	CHEMBL84931	Alpha-2A adrenergic receptor			 501							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403974&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44318454	163352998		CHEMBL84931				ZINC13437207	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985825	CN(C)CC1CC2N(O1)c1cc(Cl)ccc1Cc1ccccc21	InChI=1S/C19H21ClN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3	JTLCTTWVUAIQHD-UHFFFAOYSA-N	50403975	CHEMBL315772	Alpha-2A adrenergic receptor			 479							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403975&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10381889	163352999		CHEMBL315772				ZINC13437085	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985855	CN(C)CC1CC2N(O1)c1cc(C)ccc1Cc1ccccc21	InChI=1S/C20H24N2O/c1-14-8-9-16-11-15-6-4-5-7-18(15)20-12-17(13-21(2)3)23-22(20)19(16)10-14/h4-10,17,20H,11-13H2,1-3H3	IEMJYQZKJFERDW-UHFFFAOYSA-N	50403978	CHEMBL85735	Alpha-2A adrenergic receptor			<1000							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403978	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403978&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44318842	163353002		CHEMBL85735				ZINC13437098	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50985862	CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1	BTSCZNWXJQSJIE-QFBILLFUSA-N	50146360	CHEMBL328573::Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine	Alpha-2A adrenergic receptor			 372							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146360&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9839081	104034979		CHEMBL328573				ZINC13436820	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50996256	CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1	InChI=1S/C32H32N4O3/c1-20-16-25(30-33-21(2)39-34-30)8-9-26(20)22-4-6-23(7-5-22)31(37)36-13-10-24-17-29-27(18-28(24)36)32(19-38-29)11-14-35(3)15-12-32/h4-9,16-18H,10-15,19H2,1-3H3	ATQMRMGXINTJHV-UHFFFAOYSA-N	50084959	11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo-[2,3-f]indole-3,4'-piperidine](SB-224289)::4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl-1'-methylspiro[3,5,6,7-tetrahydro-2H-furo[2,3-f]indole-3,4'-(hexahydropyridine)]-5-ylmethanone::CHEMBL281350::SB-224289::[2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-yl]-[3-(1-methyl-piperidine)-2,3,6,7-tetrahydro-1-oxa-5-aza-s-indacen-5-yl]-methanone	Alpha-2A adrenergic receptor		>1000								ChEMBL	10.1021/jm970457s	10.7270/Q2XS5WMN	9548813			Gaster, LM; Blaney, FE; Davies, S; Duckworth, DM; Ham, P; Jenkins, S; Jennings, AJ; Joiner, GF; King, FD; Mulholland, KR; Wyman, PA; Hagan, JJ; Hatcher, J; Jones, BJ; Middlemiss, DN; Price, GW; Riley, G; Roberts, C; Routledge, C; Selkirk, J; Slade, PD	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084959&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3378093	103984445	64069	CHEMBL281350		130		ZINC01485772	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013544	CC(OC1=NCCN1)c1ccccc1	InChI=1S/C11H14N2O/c1-9(10-5-3-2-4-6-10)14-11-12-7-8-13-11/h2-6,9H,7-8H2,1H3,(H,12,13)	MPCNSEQVVHOHGO-UHFFFAOYSA-N	50415135	CHEMBL571314	Alpha-2A adrenergic receptor		 27								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415135&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487144	163364159		CHEMBL571314				ZINC45255751	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013545	CC(OC1=NCCN1)c1ccccc1CC=C	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MCAGSCISRRGDGQ-UHFFFAOYSA-N	50415136	CHEMBL570973	Alpha-2A adrenergic receptor		 58								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415136&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487145	163364160		CHEMBL570973				ZINC45257642	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013546	CC(OC1=NCCN1)c1ccccc1C	InChI=1S/C12H16N2O/c1-9-5-3-4-6-11(9)10(2)15-12-13-7-8-14-12/h3-6,10H,7-8H2,1-2H3,(H,13,14)	NGYGSYPEYBVPQK-UHFFFAOYSA-N	50415137	CHEMBL570863	Alpha-2A adrenergic receptor		 25								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415137&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487089	163364161		CHEMBL570863				ZINC45254599	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013547	CCCc1ccccc1C(C)OC1=NCCN1	InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	CKZOGIXOGHVXNW-UHFFFAOYSA-N	50415138	CHEMBL576078	Alpha-2A adrenergic receptor		 50								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415138&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487955	163364162		CHEMBL576078				ZINC45301117	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013548	CC(OC1=NCCN1)c1ccccc1C1CC1	InChI=1S/C14H18N2O/c1-10(17-14-15-8-9-16-14)12-4-2-3-5-13(12)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	BGPHEWUAKSHOBD-UHFFFAOYSA-N	50415139	CHEMBL576623	Alpha-2A adrenergic receptor		 23								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415139&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487956	163364163		CHEMBL576623				ZINC45290491	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013549	C(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	YAORIDZYZDUZCM-UHFFFAOYSA-N	50027060	2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole::2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole (cirazoline)::CHEMBL13852::CIRAZOLINE	Alpha-2A adrenergic receptor		 59								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027060&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2765	103936642		CHEMBL13852	DB09202	515		ZINC00001160	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013550	CCCc1ccccc1COC1=NCCN1	InChI=1S/C13H18N2O/c1-2-5-11-6-3-4-7-12(11)10-16-13-14-8-9-15-13/h3-4,6-7H,2,5,8-10H2,1H3,(H,14,15)	XBWFPEVESQMIBM-UHFFFAOYSA-N	50415140	CHEMBL569933	Alpha-2A adrenergic receptor		 49								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415140&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487962	163364164		CHEMBL569933				ZINC45255608	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013567	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2A adrenergic receptor					 372					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51013582	Cc1ccccc1COC1=NCCN1	InChI=1S/C11H14N2O/c1-9-4-2-3-5-10(9)8-14-11-12-6-7-13-11/h2-5H,6-8H2,1H3,(H,12,13)	LGTDYALRCIBCMI-UHFFFAOYSA-N	50415141	CHEMBL576819	Alpha-2A adrenergic receptor		 35								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415141&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487958	163364165		CHEMBL576819				ZINC45299429	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006781	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2A adrenergic receptor					 372					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006810	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2A adrenergic receptor					 115					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006813	C1CN=C(N1)C(Oc1ccccc1-c1ccccc1)c1ccccc1	InChI=1S/C22H20N2O/c1-3-9-17(10-4-1)19-13-7-8-14-20(19)25-21(22-23-15-16-24-22)18-11-5-2-6-12-18/h1-14,21H,15-16H2,(H,23,24)	XXOSLSPHUHLICG-UHFFFAOYSA-N	50412257	CHEMBL523048	Alpha-2A adrenergic receptor					 1000					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412257&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906200	163361281		CHEMBL523048				ZINC40957110	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006814	CC(Oc1ccccc1C1CCCCC1)C1=NCCN1	InChI=1S/C17H24N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h5-6,9-10,13-14H,2-4,7-8,11-12H2,1H3,(H,18,19)	RIMQFOFQYZBTDB-UHFFFAOYSA-N	50412258	CHEMBL451229	Alpha-2A adrenergic receptor					 79					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412258&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23622576	163361282		CHEMBL451229				ZINC40836200	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006834	CC(Oc1ccccc1)C1=NCCN1	InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	MDFFTELFADBPIZ-UHFFFAOYSA-N	50412260	CHEMBL273485	Alpha-2A adrenergic receptor		 27								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412260&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269122	163361284		CHEMBL273485				ZINC13471581	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006837	COC1(COc2cccc(-c3ccccc3)c2O1)C1=NCCN1	InChI=1S/C18H18N2O3/c1-21-18(17-19-10-11-20-17)12-22-15-9-5-8-14(16(15)23-18)13-6-3-2-4-7-13/h2-9H,10-12H2,1H3,(H,19,20)	TVDZYHOTHAFPBR-UHFFFAOYSA-N	50412252	CHEMBL492648	Alpha-2A adrenergic receptor		 126								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412252&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906243	163361276		CHEMBL492648				ZINC45506014	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006838	COC1(COc2c(O1)cccc2-c1ccccc1)C1=NCCN1	InChI=1S/C18H18N2O3/c1-21-18(17-19-10-11-20-17)12-22-16-14(8-5-9-15(16)23-18)13-6-3-2-4-7-13/h2-9H,10-12H2,1H3,(H,19,20)	NXCHMDJNSMDGIA-UHFFFAOYSA-N	50412259	CHEMBL492647	Alpha-2A adrenergic receptor		 257								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412259&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906242	163361283		CHEMBL492647				ZINC40423272	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006839	C1CN=C(N1)C1COc2cccc(-c3ccccc3)c2O1	InChI=1S/C17H16N2O2/c1-2-5-12(6-3-1)13-7-4-8-14-16(13)21-15(11-20-14)17-18-9-10-19-17/h1-8,15H,9-11H2,(H,18,19)	LOGUSYSMQQMCJG-UHFFFAOYSA-N	50412253	CHEMBL522151	Alpha-2A adrenergic receptor		 240								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412253&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906241	163361277		CHEMBL522151				ZINC40949724	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006840	C1CN=C(N1)C1COc2ccc(cc2O1)-c1ccccc1	InChI=1S/C17H16N2O2/c1-2-4-12(5-3-1)13-6-7-14-15(10-13)21-16(11-20-14)17-18-8-9-19-17/h1-7,10,16H,8-9,11H2,(H,18,19)	CENDKGWAICPCEX-UHFFFAOYSA-N	50412254	CHEMBL492445	Alpha-2A adrenergic receptor		 398								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412254&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906203	163361278		CHEMBL492445				ZINC40949721	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006841	C1CN=C(N1)C1COc2cc(ccc2O1)-c1ccccc1	InChI=1S/C17H16N2O2/c1-2-4-12(5-3-1)13-6-7-14-15(10-13)20-11-16(21-14)17-18-8-9-19-17/h1-7,10,16H,8-9,11H2,(H,18,19)	MOEPMTDKDUFBNH-UHFFFAOYSA-N	50412255	CHEMBL492444	Alpha-2A adrenergic receptor		 282								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412255&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906202	163361279		CHEMBL492444				ZINC40949717	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006842	C1CN=C(N1)C1COc2c(O1)cccc2-c1ccccc1	InChI=1S/C17H16N2O2/c1-2-5-12(6-3-1)13-7-4-8-14-16(13)20-11-15(21-14)17-18-9-10-19-17/h1-8,15H,9-11H2,(H,18,19)	MQSPJCMZCOHHPI-UHFFFAOYSA-N	50412256	CHEMBL493272	Alpha-2A adrenergic receptor		 724								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412256&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906201	163361280		CHEMBL493272				ZINC40431295	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006845	CC(Oc1ccccc1C1CCCC1)C1=NCCN1	InChI=1S/C16H22N2O/c1-12(16-17-10-11-18-16)19-15-9-5-4-8-14(15)13-6-2-3-7-13/h4-5,8-9,12-13H,2-3,6-7,10-11H2,1H3,(H,17,18)	WIQCERUTOBWUOL-UHFFFAOYSA-N	50412244	CHEMBL495096	Alpha-2A adrenergic receptor		 50								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412244&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906199	163361268		CHEMBL495096				ZINC40430700	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006846	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2A adrenergic receptor		 58								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006847	CC(Oc1ccccc1\C=N\OCc1ccccc1)C1=NCCN1	InChI=1S/C19H21N3O2/c1-15(19-20-11-12-21-19)24-18-10-6-5-9-17(18)13-22-23-14-16-7-3-2-4-8-16/h2-10,13,15H,11-12,14H2,1H3,(H,20,21)/b22-13+	KUWSYGHOSHDWCB-LPYMAVHISA-N	50412246	CHEMBL495097	Alpha-2A adrenergic receptor		 214								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412246&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906197	163361270		CHEMBL495097				ZINC40957611	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006848	CCO\N=C\c1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H19N3O2/c1-3-18-17-10-12-6-4-5-7-13(12)19-11(2)14-15-8-9-16-14/h4-7,10-11H,3,8-9H2,1-2H3,(H,15,16)/b17-10+	BVWLLEDYRCHASI-LICLKQGHSA-N	50412247	CHEMBL492639	Alpha-2A adrenergic receptor		 417								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412247&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906196	163361271		CHEMBL492639				ZINC45506721	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006849	CC(Oc1ccccc1CN=O)C1=NCCN1	InChI=1S/C12H15N3O2/c1-9(12-13-6-7-14-12)17-11-5-3-2-4-10(11)8-15-16/h2-5,9H,6-8H2,1H3,(H,13,14)	FZLNIHYBYXMHEO-UHFFFAOYSA-N	50412249	CHEMBL493675	Alpha-2A adrenergic receptor		 288								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412249&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91900410	163361273		CHEMBL493675				ZINC40430963	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006851	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2A adrenergic receptor		 0.363078								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006852	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2A adrenergic receptor		 7.1								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006853	C1CN=C(N1)C(Oc1ccccc1)c1ccccc1	InChI=1S/C16H16N2O/c1-3-7-13(8-4-1)15(16-17-11-12-18-16)19-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H,17,18)	OABROWXKGQFLDH-UHFFFAOYSA-N	50412251	CHEMBL494885	Alpha-2A adrenergic receptor		 93								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412251&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44568614	163361275		CHEMBL494885				ZINC40972334	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51006862	CO\N=C\c1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H17N3O2/c1-10(13-14-7-8-15-13)18-12-6-4-3-5-11(12)9-16-17-2/h3-6,9-10H,7-8H2,1-2H3,(H,14,15)/b16-9+	YTQHOBJMFUQZEK-CXUHLZMHSA-N	50412248	CHEMBL442815	Alpha-2A adrenergic receptor		 661								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412248&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906160	163361272		CHEMBL442815				ZINC40822924	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50519764	C(Nc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C16H17N3/c1-2-6-13(7-3-1)14-8-4-5-9-15(14)19-12-16-17-10-11-18-16/h1-9,19H,10-12H2,(H,17,18)	RJDGUOVDCSODNG-UHFFFAOYSA-N	50000214	CHEMBL337862	Alpha-2A adrenergic receptor					 63					ChEMBL	10.1021/acsmedchemlett.6b00290	10.7270/Q2086784	27774136			Giusepponi, ME; Cifani, C; Micioni Di Bonaventura, MV; Mattioli, L; Hudson, A; Diamanti, E; Del Bello, F; Giannella, M; Mammoli, V; Paoletti, CD; Piergentili, A; Pigini, M; Quaglia, W	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000214&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352155	242055754		CHEMBL337862					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561109	C1CC1C(NC1=NCCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)	CQXADFVORZEARL-UHFFFAOYSA-N	50070328	CHEBI:8862::Rilmenidine	Alpha-2A adrenergic receptor					 275					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070328&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68712	313072381					C11120		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51027264	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2A adrenergic receptor		 58								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51027265	C[C@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m0/s1	SEKAQUSPSDPIAN-NSHDSACASA-N	50420342	CHEMBL2089156	Alpha-2A adrenergic receptor		 42								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70695474	163369366		CHEMBL2089156					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018901	CC(Oc1ccccc1)C1=NCCN1	InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	MDFFTELFADBPIZ-UHFFFAOYSA-N	50412260	CHEMBL273485	Alpha-2A adrenergic receptor		 27								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412260&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269122	163361284		CHEMBL273485				ZINC13471581	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018906	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2A adrenergic receptor		 81								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018907	C[C@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	NMSAVNXFCXMJJY-LBPRGKRZSA-N	50417341	CHEMBL397753	Alpha-2A adrenergic receptor		 72								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417341&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757182	163366365		CHEMBL397753				ZINC13585595	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018908	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2A adrenergic receptor		 58								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018909	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2A adrenergic receptor		 100								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018910	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2A adrenergic receptor		 52								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018911	CC(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	QYCJTZDZQXSXSC-UHFFFAOYSA-N	50417344	CHEMBL1276218	Alpha-2A adrenergic receptor		 23								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417344&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44549156	163366368		CHEMBL1276218				ZINC64393121	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018912	C[C@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m0/s1	QYCJTZDZQXSXSC-JTQLQIEISA-N	50417346	CHEMBL1276220	Alpha-2A adrenergic receptor		 21								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836303	163366370		CHEMBL1276220					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018914	C[C@@H](Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)/t11-/m1/s1	IAIZHDGEGFGNMO-LLVKDONJSA-N	50417348	CHEMBL1276247	Alpha-2A adrenergic receptor		 166								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417348&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836306	163366372		CHEMBL1276247					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018915	C[C@H](Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)/t11-/m0/s1	IAIZHDGEGFGNMO-NSHDSACASA-N	50417349	CHEMBL1276248	Alpha-2A adrenergic receptor		 45								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417349&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836305	163366373		CHEMBL1276248					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018916	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2A adrenergic receptor		 28								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018917	C[C@@H](Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	XGMNRALXOWECNG-GFCCVEGCSA-N	50417351	CHEMBL1278084	Alpha-2A adrenergic receptor		 40								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836308	163366375		CHEMBL1278084					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018918	C[C@H](Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	XGMNRALXOWECNG-LBPRGKRZSA-N	50417352	CHEMBL1278085	Alpha-2A adrenergic receptor		 98								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417352&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836307	163366376		CHEMBL1278085					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018919	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2A adrenergic receptor					 115					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018920	C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m1/s1	OGOLMGZJNRNULQ-CYBMUJFWSA-N	50417353	CHEMBL242265	Alpha-2A adrenergic receptor					 28840					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417353&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11043720	163366377		CHEMBL242265				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018921	C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m0/s1	OGOLMGZJNRNULQ-ZDUSSCGKSA-N	50417354	CHEMBL396013	Alpha-2A adrenergic receptor					 74					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417354&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10333157	163366378		CHEMBL396013				ZINC00009140	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018922	CC(Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)	IAIZHDGEGFGNMO-UHFFFAOYSA-N	50417347	CHEMBL385310	Alpha-2A adrenergic receptor					 76					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11371902	163366371		CHEMBL385310				ZINC13585567	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018925	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor					 8.3					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51018959	C[C@@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m1/s1	QYCJTZDZQXSXSC-SNVBAGLBSA-N	50417345	CHEMBL1276219	Alpha-2A adrenergic receptor		 45								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417345&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836304	163366369		CHEMBL1276219					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025401	CC(Oc1c(cccc1-c1ccccc1)-c1ccccc1)C1=NCCN1	InChI=1S/C23H22N2O/c1-17(23-24-15-16-25-23)26-22-20(18-9-4-2-5-10-18)13-8-14-21(22)19-11-6-3-7-12-19/h2-14,17H,15-16H2,1H3,(H,24,25)	YCFVUTASHGKCKL-UHFFFAOYSA-N	50419873	CHEMBL1956203	Alpha-2A adrenergic receptor		 490								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419873&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395732	163368897		CHEMBL1956203				ZINC73311702	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025430	CC(Oc1ccccc1S(C)(=O)=O)C1=NCCN1	InChI=1S/C12H16N2O3S/c1-9(12-13-7-8-14-12)17-10-5-3-4-6-11(10)18(2,15)16/h3-6,9H,7-8H2,1-2H3,(H,13,14)	BUVSDNNKXQXCRO-UHFFFAOYSA-N	50419882	CHEMBL1956200	Alpha-2A adrenergic receptor					 562					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419882&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57400959	163368906		CHEMBL1956200				ZINC73312436	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025431	CC(Oc1ccccc1C=O)C1=NCCN1	InChI=1S/C12H14N2O2/c1-9(12-13-6-7-14-12)16-11-5-3-2-4-10(11)8-15/h2-5,8-9H,6-7H2,1H3,(H,13,14)	UQOROHPPKUMVNP-UHFFFAOYSA-N	50419883	CHEMBL1956201	Alpha-2A adrenergic receptor					 32					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419883&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57402718	163368907		CHEMBL1956201				ZINC73312440	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025432	CC(Oc1ccccc1C(C)=O)C1=NCCN1	InChI=1S/C13H16N2O2/c1-9(16)11-5-3-4-6-12(11)17-10(2)13-14-7-8-15-13/h3-6,10H,7-8H2,1-2H3,(H,14,15)	LHYRGWVECGKEOM-UHFFFAOYSA-N	50419888	CHEMBL1956202	Alpha-2A adrenergic receptor					 63					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419888&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395731	163368912		CHEMBL1956202				ZINC73312444	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025434	CCc1cccc(CC)c1OC(C)C1=NCCN1	InChI=1S/C15H22N2O/c1-4-12-7-6-8-13(5-2)14(12)18-11(3)15-16-9-10-17-15/h6-8,11H,4-5,9-10H2,1-3H3,(H,16,17)	OXGCVSXSSWZTMU-UHFFFAOYSA-N	50419884	CHEMBL157955	Alpha-2A adrenergic receptor					 12					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419884&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371864	163368908		CHEMBL157955				ZINC27705893	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025473	CC(Oc1ccccc1Cl)C1=NCCN1	InChI=1S/C11H13ClN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	ARHDCTCZSSOSFG-UHFFFAOYSA-N	50419890	CHEMBL1956191	Alpha-2A adrenergic receptor		 29								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419890&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345625	163368914		CHEMBL1956191				ZINC73314283	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025474	CC(Oc1ccccc1Br)C1=NCCN1	InChI=1S/C11H13BrN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	NFGYJBCMYUYKCI-UHFFFAOYSA-N	50419874	CHEMBL1956192	Alpha-2A adrenergic receptor		 23								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419874&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345626	163368898		CHEMBL1956192				ZINC73315479	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025475	CC(Oc1ccccc1C(F)(F)F)C1=NCCN1	InChI=1S/C12H13F3N2O/c1-8(11-16-6-7-17-11)18-10-5-3-2-4-9(10)12(13,14)15/h2-5,8H,6-7H2,1H3,(H,16,17)	BFKLSSIIDDEGQB-UHFFFAOYSA-N	50419875	CHEMBL1956193	Alpha-2A adrenergic receptor		 182								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419875&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395663	163368899		CHEMBL1956193				ZINC73314893	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025476	CC(Oc1ccccc1C(C)=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(2)12-6-4-5-7-13(12)17-11(3)14-15-8-9-16-14/h4-7,11H,1,8-9H2,2-3H3,(H,15,16)	HVCWUSZDSFHZDW-UHFFFAOYSA-N	50419877	CHEMBL1956194	Alpha-2A adrenergic receptor		 72								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419877&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345627	163368901		CHEMBL1956194				ZINC73313031	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025477	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2A adrenergic receptor		 36								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025478	CCOc1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H18N2O2/c1-3-16-11-6-4-5-7-12(11)17-10(2)13-14-8-9-15-13/h4-7,10H,3,8-9H2,1-2H3,(H,14,15)	DYQQPAOLMYPZKE-UHFFFAOYSA-N	50419879	CHEMBL1956196	Alpha-2A adrenergic receptor		 98								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419879&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57399145	163368903		CHEMBL1956196				ZINC73312418	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025479	CC(C)Oc1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O2/c1-10(2)17-12-6-4-5-7-13(12)18-11(3)14-15-8-9-16-14/h4-7,10-11H,8-9H2,1-3H3,(H,15,16)	YQBKUZKHVPTFOO-UHFFFAOYSA-N	50419887	CHEMBL14208	Alpha-2A adrenergic receptor		 83								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419887&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269140	163368911		CHEMBL14208				ZINC13805996	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025480	COc1ccccc1OC(C)C1=NCCN1	InChI=1S/C12H16N2O2/c1-9(12-13-7-8-14-12)16-11-6-4-3-5-10(11)15-2/h3-6,9H,7-8H2,1-2H3,(H,13,14)	SQPFWLZXWYXMCI-UHFFFAOYSA-N	50419881	CHEMBL1956199	Alpha-2A adrenergic receptor		 58								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419881&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57402717	163368905		CHEMBL1956199				ZINC73312431	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025484	CC(Oc1c(C)cccc1C)C1=NCCN1	InChI=1S/C13H18N2O/c1-9-5-4-6-10(2)12(9)16-11(3)13-14-7-8-15-13/h4-6,11H,7-8H2,1-3H3,(H,14,15)	JWAAXMLRAVOKBQ-UHFFFAOYSA-N	50419889	CHEMBL155866	Alpha-2A adrenergic receptor		 12								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419889&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371755	163368913		CHEMBL155866				ZINC27710505	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025486	CC(Oc1c(CC=C)cccc1CC=C)C1=NCCN1	InChI=1S/C17H22N2O/c1-4-7-14-9-6-10-15(8-5-2)16(14)20-13(3)17-18-11-12-19-17/h4-6,9-10,13H,1-2,7-8,11-12H2,3H3,(H,18,19)	YAYASQTZIRSRFB-UHFFFAOYSA-N	50419885	CHEMBL157206	Alpha-2A adrenergic receptor		 17								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419885&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371744	163368909		CHEMBL157206				ZINC27712333	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025491	CC(C)c1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O/c1-10(2)12-6-4-5-7-13(12)17-11(3)14-15-8-9-16-14/h4-7,10-11H,8-9H2,1-3H3,(H,15,16)	DAEHQHNTEAMXQC-UHFFFAOYSA-N	50419876	CHEMBL266613	Alpha-2A adrenergic receptor		 72								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419876&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269089	163368900		CHEMBL266613				ZINC13805985	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025493	CCc1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H18N2O/c1-3-11-6-4-5-7-12(11)16-10(2)13-14-8-9-15-13/h4-7,10H,3,8-9H2,1-2H3,(H,14,15)	RUFDXBQFEDFKDE-UHFFFAOYSA-N	50419886	CHEMBL156336	Alpha-2A adrenergic receptor		 24								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419886	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419886&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371745	163368910		CHEMBL156336				ZINC27712342	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025494	CC(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C14H18N2O2/c1-10(14-15-8-9-16-14)17-12-4-2-3-5-13(12)18-11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	OHLOMHGVALXPJP-UHFFFAOYSA-N	50419880	CHEMBL1956197	Alpha-2A adrenergic receptor		 83								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419880&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345629	163368904		CHEMBL1956197				ZINC73312422	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025495	CC(Oc1c(Cl)cccc1Cl)C1=NCCN1	InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)	KSMAGQUYOIHWFS-UHFFFAOYSA-N	50019646	2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline::2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL17860::lofexidine	Alpha-2A adrenergic receptor		 4.4								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019646&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			30668	103930569	51368	CHEMBL17860	DB04948			ZINC00005626	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025605	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2A adrenergic receptor		 7.1								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025606	C1CN=C(N1)[C@@H]1CO[C@@H](CO1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-17-12(9-16-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12-/m0/s1	MPFNVJVLRBBPHX-RYUDHWBXSA-N	50419925	CHEMBL1956899	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419925&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57393066	163368949		CHEMBL1956899				ZINC73296457	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025608	C1CN=C(N1)[C@@H]1CO[C@H](CO1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-17-12(9-16-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12+/m1/s1	MPFNVJVLRBBPHX-NEPJUHHUSA-N	50419926	CHEMBL1956901	Alpha-2A adrenergic receptor		 7943								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419926&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57399991	163368950		CHEMBL1956901				ZINC73294104	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025609	C1CN=C(N1)[C@@H]1COC[C@@H](O1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-16-9-12(17-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12+/m1/s1	OQACXTOHBUWXII-NEPJUHHUSA-N	50419927	CHEMBL1956903	Alpha-2A adrenergic receptor		 5370								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419927&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57394788	163368951		CHEMBL1956903				ZINC73313925	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025610	C1CN=C(N1)[C@@H]1COC[C@H](O1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-16-9-12(17-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12-/m0/s1	OQACXTOHBUWXII-RYUDHWBXSA-N	50419928	CHEMBL1956904	Alpha-2A adrenergic receptor		 6310								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419928&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57394789	163368952		CHEMBL1956904				ZINC73313928	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025611	C1CN=C(N1)C1COC(CO1)(c1ccccc1)c1ccccc1	InChI=1S/C19H20N2O2/c1-3-7-15(8-4-1)19(16-9-5-2-6-10-16)14-22-17(13-23-19)18-20-11-12-21-18/h1-10,17H,11-14H2,(H,20,21)	GTRWYVABSCIMJN-UHFFFAOYSA-N	50419929	CHEMBL1956905	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419929	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419929&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57403508	163368953		CHEMBL1956905				ZINC73297098	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025612	C1CN=C(N1)C1COCC(O1)(c1ccccc1)c1ccccc1	InChI=1S/C19H20N2O2/c1-3-7-15(8-4-1)19(16-9-5-2-6-10-16)14-22-13-17(23-19)18-20-11-12-21-18/h1-10,17H,11-14H2,(H,20,21)	VMIZIRROPNWIIU-UHFFFAOYSA-N	50419930	CHEMBL1956906	Alpha-2A adrenergic receptor		 3802								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419930&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57401787	163368954		CHEMBL1956906				ZINC73313936	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51025630	C1CN=C(N1)[C@H]1CO[C@@H](CO1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-17-12(9-16-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12+/m0/s1	MPFNVJVLRBBPHX-NWDGAFQWSA-N	50419931	CHEMBL1956902	Alpha-2A adrenergic receptor		 398								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419931&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57384051	163368955		CHEMBL1956902				ZINC73310317	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51030468	CN(C)CC1CC2N(O1)c1cc(Cl)ccc1Cc1ccccc21	InChI=1S/C19H21ClN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3	JTLCTTWVUAIQHD-UHFFFAOYSA-N	50403975	CHEMBL315772	Alpha-2A adrenergic receptor			 479							ChEMBL	10.1016/s0960-894x(02)00796-5	10.7270/Q26M384X	12443779			Andres, JI; Alonso, JM; Fernandez, J; Iturrino, L; Martinez, P; Meert, TF; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403975&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10381889	163352999		CHEMBL315772				ZINC13437085	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51030474	CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1	BTSCZNWXJQSJIE-QFBILLFUSA-N	50146360	CHEMBL328573::Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine	Alpha-2A adrenergic receptor			 372							ChEMBL	10.1016/s0960-894x(02)00796-5	10.7270/Q26M384X	12443779			Andres, JI; Alonso, JM; Fernandez, J; Iturrino, L; Martinez, P; Meert, TF; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146360&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9839081	104034979		CHEMBL328573				ZINC13436820	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51027233	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2A adrenergic receptor		 100								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51027234	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2A adrenergic receptor		 52								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51027235	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2A adrenergic receptor		 36								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51027236	C[C@@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m1/s1	SEKAQUSPSDPIAN-LLVKDONJSA-N	50420341	CHEMBL2089155	Alpha-2A adrenergic receptor		 45								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420341&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70693375	163369365		CHEMBL2089155					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50587083	CN(C)CC1CC2N(O1)c1cnccc1Cc1ccccc21	InChI=1S/C18H21N3O/c1-20(2)12-15-10-17-16-6-4-3-5-13(16)9-14-7-8-19-11-18(14)21(17)22-15/h3-8,11,15,17H,9-10,12H2,1-2H3	QQWLSTBNUSPPGV-UHFFFAOYSA-N	50421589	CHEMBL331077	Alpha-2A adrenergic receptor			<1000							ChEMBL	10.1016/s0960-894x(02)00796-5	10.7270/Q26M384X	12443779			Andres, JI; Alonso, JM; Fernandez, J; Iturrino, L; Martinez, P; Meert, TF; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421589&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10108561	164150464		CHEMBL331077				ZINC27182066	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50587088	CN(C)CC1CC2N(O1)c1ccccc1Cc1ncccc21	InChI=1S/C18H21N3O/c1-20(2)12-14-11-18-15-7-5-9-19-16(15)10-13-6-3-4-8-17(13)21(18)22-14/h3-9,14,18H,10-12H2,1-2H3	VPZDYZMLWKUTOB-UHFFFAOYSA-N	50421590	CHEMBL331188	Alpha-2A adrenergic receptor			<1000							ChEMBL	10.1016/s0960-894x(02)00796-5	10.7270/Q26M384X	12443779			Andres, JI; Alonso, JM; Fernandez, J; Iturrino, L; Martinez, P; Meert, TF; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421590&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44345317	164150465		CHEMBL331188				ZINC27104304	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563854	COc1ccc(CCCN2CCC(CCC(=O)c3cc(Cl)c(N)c4OCCOc34)CC2)cc1OC	InChI=1S/C27H35ClN2O5/c1-32-23-8-6-19(16-24(23)33-2)4-3-11-30-12-9-18(10-13-30)5-7-22(31)20-17-21(28)25(29)27-26(20)34-14-15-35-27/h6,8,16-18H,3-5,7,9-15,29H2,1-2H3	UVOCSZKGWJOKNN-UHFFFAOYSA-N	85027	1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3-(3,4-dimethoxyphenyl)propyl]piperidine-4-yl]propane-1-one::RS 100235	Alpha-2A adrenergic receptor		 100								ChEMBL		10.7270/Q2JM2CTV				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85027&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5311416	136351127						ZINC03813517	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563870	Cn1cc(C(=O)C(=O)N[C@H]2CN3CCC2CC3)c2ccccc12	InChI=1S/C18H21N3O2/c1-20-10-14(13-4-2-3-5-16(13)20)17(22)18(23)19-15-11-21-8-6-12(15)7-9-21/h2-5,10,12,15H,6-9,11H2,1H3,(H,19,23)/t15-/m0/s1	ZNAPADWWBWFMCQ-HNNXBMFYSA-N	50213344	CHEMBL294649	Alpha-2A adrenergic receptor		 7943								ChEMBL		10.7270/Q2XS5XJ5				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213344&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6604789	376070924		CHEMBL294649					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50563898	Cn1cc(C(=O)C(=O)N[C@@H]2CN3CCC2CC3)c2ccccc12	InChI=1S/C18H21N3O2/c1-20-10-14(13-4-2-3-5-16(13)20)17(22)18(23)19-15-11-21-8-6-12(15)7-9-21/h2-5,10,12,15H,6-9,11H2,1H3,(H,19,23)/t15-/m1/s1	ZNAPADWWBWFMCQ-OAHLLOKOSA-N	50213343	CHEMBL298612	Alpha-2A adrenergic receptor		 31623								ChEMBL		10.7270/Q2XS5XJ5				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213343&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10337773	376070923		CHEMBL298612					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564045	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2A adrenergic receptor					 0.616595					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564080	Brc1c(NC2=NCCN2)ccc2NCCNc12	InChI=1S/C11H14BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-2,13-14H,3-6H2,(H2,15,16,17)	CETMNKCDAHCKRC-UHFFFAOYSA-N	50213028	CHEMBL74283	Alpha-2A adrenergic receptor					 2.8					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213028&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			131829	376070773		CHEMBL74283					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564098	Brc1c(NC2=NCCS2)ccc2nccnc12	InChI=1S/C11H9BrN4S/c12-9-7(16-11-15-5-6-17-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H,15,16)	KSVHJUZGYJOCLG-UHFFFAOYSA-N	50213350	CHEMBL73392	Alpha-2A adrenergic receptor					 2754					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213350&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44312037	376070930		CHEMBL73392					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564247	Brc1c(NC2=N[C@@H]3CCCC[C@@H]3N2)ccc2nccnc12	InChI=1S/C15H16BrN5/c16-13-11(5-6-12-14(13)18-8-7-17-12)21-15-19-9-3-1-2-4-10(9)20-15/h5-10H,1-4H2,(H2,19,20,21)/t9-,10+	MIYQUCZRQJRHHG-AOOOYVTPSA-N	50213349	CHEMBL74342	Alpha-2A adrenergic receptor		 14791								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213349&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311789	376070929		CHEMBL74342					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564250	Brc1c(NC2=NCCN2)ccc2NCCNc12	InChI=1S/C11H14BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-2,13-14H,3-6H2,(H2,15,16,17)	CETMNKCDAHCKRC-UHFFFAOYSA-N	50213028	CHEMBL74283	Alpha-2A adrenergic receptor		 6.5								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213028&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			131829	376070773		CHEMBL74283					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564253	Cc1cnc2c(Br)c(NC3=NCCN3)ccc2n1	InChI=1S/C12H12BrN5/c1-7-6-16-11-9(17-7)3-2-8(10(11)13)18-12-14-4-5-15-12/h2-3,6H,4-5H2,1H3,(H2,14,15,18)	ICROYPJYNVAMQF-UHFFFAOYSA-N	50213351	CHEMBL72147	Alpha-2A adrenergic receptor		 74								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			15675860	376070931		CHEMBL72147					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564254	Cc1cnc2c(Br)c(NC3=NCCN3)ccc2n1	InChI=1S/C12H12BrN5/c1-7-6-16-11-9(17-7)3-2-8(10(11)13)18-12-14-4-5-15-12/h2-3,6H,4-5H2,1H3,(H2,14,15,18)	ICROYPJYNVAMQF-UHFFFAOYSA-N	50213351	CHEMBL72147	Alpha-2A adrenergic receptor					 851					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213351&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			15675860	376070931		CHEMBL72147					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564255	Clc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10ClN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	VJQWCCBDYLTRPZ-UHFFFAOYSA-N	50213348	CHEMBL72753	Alpha-2A adrenergic receptor		 37								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213348&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3086326	376070928		CHEMBL72753					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50564261	Clc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10ClN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	VJQWCCBDYLTRPZ-UHFFFAOYSA-N	50213348	CHEMBL72753	Alpha-2A adrenergic receptor					 2.3					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213348&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3086326	376070928		CHEMBL72753					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561170	C1CN=C(NC2CCCc3ccccc23)O1	InChI=1S/C13H16N2O/c1-2-6-11-10(4-1)5-3-7-12(11)15-13-14-8-9-16-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)	FXNNPMSELIMMHU-UHFFFAOYSA-N	50212995	CHEMBL75030	Alpha-2A adrenergic receptor		 2.3								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212995&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			218362	376070740		CHEMBL75030					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561171	C1CN=C(NC2CCCCCC2)O1	InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)	DAIRUBYTBODIKT-UHFFFAOYSA-N	50212993	CHEMBL305928	Alpha-2A adrenergic receptor					 38					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212993&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			294234	376070738		CHEMBL305928					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561173	C1CN=C(O1)N1CCOCC1	InChI=1S/C7H12N2O2/c1-4-11-7(8-1)9-2-5-10-6-3-9/h1-6H2	ICFHSWCDTICIIC-UHFFFAOYSA-N	50212994	CHEMBL75201	Alpha-2A adrenergic receptor		 16596								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212994&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			21392988	376070739		CHEMBL75201					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561183	C1CN=C(NC2CCCc3ccccc23)O1	InChI=1S/C13H16N2O/c1-2-6-11-10(4-1)5-3-7-12(11)15-13-14-8-9-16-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)	FXNNPMSELIMMHU-UHFFFAOYSA-N	50212995	CHEMBL75030	Alpha-2A adrenergic receptor					 1.2					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212995&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			218362	376070740		CHEMBL75030					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561190	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor		 7.9								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561195	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2A adrenergic receptor					 8.1					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561200	C1CN=C(NC2CCCCCC2)O1	InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)	DAIRUBYTBODIKT-UHFFFAOYSA-N	50212993	CHEMBL305928	Alpha-2A adrenergic receptor		 5.4								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212993&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			294234	376070738		CHEMBL305928					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561201	C1CC1C(NC1=NCCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)	CQXADFVORZEARL-UHFFFAOYSA-N	50070328	CHEBI:8862::Rilmenidine	Alpha-2A adrenergic receptor		 182								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070328&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68712	313072381					C11120		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561211	CCC[C@H]1CCCCC1NC1=NCCO1	InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11?/m0/s1	WDSZUSABLKNHCZ-VUWPPUDQSA-N	50212997	CHEMBL310335	Alpha-2A adrenergic receptor		 3.0								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212997&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314198	376070742		CHEMBL310335					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561222	C1COC(NC2CCCc3ccccc23)=NC1	InChI=1S/C14H18N2O/c1-2-7-12-11(5-1)6-3-8-13(12)16-14-15-9-4-10-17-14/h1-2,5,7,13H,3-4,6,8-10H2,(H,15,16)	LAMFPOWZDAOQTK-UHFFFAOYSA-N	50212996	CHEMBL306377	Alpha-2A adrenergic receptor		 26								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212996&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314200	376070741		CHEMBL306377					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561234	C1COC(NC2CCCc3ccccc23)=NC1	InChI=1S/C14H18N2O/c1-2-7-12-11(5-1)6-3-8-13(12)16-14-15-9-4-10-17-14/h1-2,5,7,13H,3-4,6,8-10H2,(H,15,16)	LAMFPOWZDAOQTK-UHFFFAOYSA-N	50212996	CHEMBL306377	Alpha-2A adrenergic receptor					 229					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212996&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314200	376070741		CHEMBL306377					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50561235	CCC[C@H]1CCCCC1NC1=NCCO1	InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11?/m0/s1	WDSZUSABLKNHCZ-VUWPPUDQSA-N	50212997	CHEMBL310335	Alpha-2A adrenergic receptor					 1.6					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212997&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314198	376070742		CHEMBL310335					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50533108	CN1CC[C@H]2CC(=O)[C@H](Cc3ccccc3)[C@H]3CCC[C@@H]1[C@H]23	InChI=1S/C20H27NO/c1-21-11-10-15-13-19(22)17(12-14-6-3-2-4-7-14)16-8-5-9-18(21)20(15)16/h2-4,6-7,15-18,20H,5,8-13H2,1H3/t15-,16+,17+,18+,20+/m0/s1	HWGSTWOVRDYFSO-VAVNGKDRSA-N	50204312	CHEMBL3936289	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2016.10.065	10.7270/Q25H7J7R	27839919			McLeod, MC; Aubé, J; Frankowski, KJ	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204312&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			134149168	375980472		CHEMBL3936289					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50533202	CCCN1CC[C@@H]2[C@@H]3[C@H](CCC[C@@H]13)[C@@H](CC)c1nc3cc(ccc3cc21)C(F)(F)F	InChI=1S/C25H31F3N2/c1-3-11-30-12-10-19-20-13-15-8-9-16(25(26,27)28)14-21(15)29-24(20)17(4-2)18-6-5-7-22(30)23(18)19/h8-9,13-14,17-19,22-23H,3-7,10-12H2,1-2H3/t17-,18-,19+,22-,23+/m1/s1	LILDBTJYRFAMFE-VCSLONGPSA-N	50204306	CHEMBL3897499	Alpha-2A adrenergic receptor		 1586								ChEMBL	10.1016/j.bmcl.2016.10.065	10.7270/Q25H7J7R	27839919			McLeod, MC; Aubé, J; Frankowski, KJ	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204306&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132584404	375980466		CHEMBL3897499					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50740166	CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)nc(nc12)C#Cc1ccc(Cl)s1	InChI=1S/C18H17ClN6O4S/c1-20-15-11-16(24-10(23-15)6-4-8-3-5-9(19)30-8)25(7-22-11)18-13(27)12(26)14(29-18)17(28)21-2/h3,5,7,12-14,18,26-27H,1-2H3,(H,21,28)(H,20,23,24)/t12-,13+,14-,18+/m0/s1	MTSSGMWKEDEGAV-MOROJQBDSA-N	50236785	CHEMBL4090355	Alpha-2A adrenergic receptor		 5000								ChEMBL	10.1021/acs.jmedchem.7b00141	10.7270/Q2Z60RBZ	28319392			Tosh, DK; Janowsky, A; Eshleman, AJ; Warnick, E; Gao, ZG; Chen, Z; Gizewski, E; Auchampach, JA; Salvemini, D; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236785&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137643541	385453339		CHEMBL4090355					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50740648	CCCNc1nc(nc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC)C#Cc1ccc(Cl)s1	InChI=1S/C20H21ClN6O4S/c1-3-8-23-17-13-18(26-12(25-17)7-5-10-4-6-11(21)32-10)27(9-24-13)20-15(29)14(28)16(31-20)19(30)22-2/h4,6,9,14-16,20,28-29H,3,8H2,1-2H3,(H,22,30)(H,23,25,26)/t14-,15+,16-,20+/m0/s1	VVAIUXGEZUTKDN-KSVNGYGVSA-N	50236779	CHEMBL4086593	Alpha-2A adrenergic receptor		 5000								ChEMBL	10.1021/acs.jmedchem.7b00141	10.7270/Q2Z60RBZ	28319392			Tosh, DK; Janowsky, A; Eshleman, AJ; Warnick, E; Gao, ZG; Chen, Z; Gizewski, E; Auchampach, JA; Salvemini, D; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236779&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137641762	385453337		CHEMBL4086593					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50731690	C1Oc2cc3CCNCc3cc2O1	InChI=1S/C10H11NO2/c1-2-11-5-8-4-10-9(3-7(1)8)12-6-13-10/h3-4,11H,1-2,5-6H2	JHLDJOBIUVJSTG-UHFFFAOYSA-N	50236732	CHEMBL4091137	Alpha-2A adrenergic receptor		<100								ChEMBL	10.1021/acs.jmedchem.7b00085	10.7270/Q2DJ5HWM	28244748			Glennon, RA	Virginia Commonwealth University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236732&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			27013	385213408		CHEMBL4091137					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50732997	O.CS(O)(=O)=O.COc1ccc2n(cc(CN3CCN(C)CC3)c2c1)S(=O)(=O)c1ccccc1Br	InChI=1S/C21H24BrN3O3S/c1-23-9-11-24(12-10-23)14-16-15-25(20-8-7-17(28-2)13-18(16)20)29(26,27)21-6-4-3-5-19(21)22/h3-8,13,15H,9-12,14H2,1-2H3	GWCYPEHWIZXYFZ-UHFFFAOYSA-N	50236754	CHEMBL4082473	Alpha-2A adrenergic receptor		 2570								ChEMBL	10.1021/acs.jmedchem.6b01662	10.7270/Q27S7R1X	28212021			Nirogi, R; Shinde, A; Kambhampati, RS; Mohammed, AR; Saraf, SK; Badange, RK; Bandyala, TR; Bhatta, V; Bojja, K; Reballi, V; Subramanian, R; Benade, V; Palacharla, RC; Bhyrapuneni, G; Jayarajan, P; Goyal, V; Jasti, V	Suven Life Sciences Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236754&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137647199	385213428		CHEMBL4082473					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50755107	Fc1cc(NCC23CCCN2CCC3)c(Cl)cc1S(=O)(=O)Nc1nccs1	InChI=1S/C17H20ClFN4O2S2/c18-12-9-15(27(24,25)22-16-20-5-8-26-16)13(19)10-14(12)21-11-17-3-1-6-23(17)7-2-4-17/h5,8-10,21H,1-4,6-7,11H2,(H,20,22)	XFWKBJBSEOZBRA-UHFFFAOYSA-N	50240277	CHEMBL4061793	Alpha-2A adrenergic receptor			 8000							ChEMBL	10.1016/j.bmcl.2017.03.085	10.7270/Q29025XB	28389149			Roecker, AJ; Egbertson, M; Jones, KLG; Gomez, R; Kraus, RL; Li, Y; Koser, AJ; Urban, MO; Klein, R; Clements, M; Panigel, J; Daley, C; Wang, J; Finger, EN; Majercak, J; Santarelli, V; Gregan, I; Cato, M; Filzen, T; Jovanovska, A; Wang, YH; Wang, D; Joyce, LA; Sherer, EC; Peng, X; Wang, X; Sun, H; Coleman, PJ; Houghton, AK; Layton, ME	Department of Discovery Chemistry Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240277&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10414708	85715666		CHEMBL4061793					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50808907	Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1	InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)	OGJGQVFWEPNYSB-UHFFFAOYSA-N	85093	CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853	Alpha-2A adrenergic receptor		 170								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	L74	6IQL	5311200	136351193		CHEMBL555670CHEMBL267014		3303		ZINC25760037	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50808908	Cc1ccc(cc1C)N1CCN(Cc2nc3ccccc3[nH]2)CC1	InChI=1S/C20H24N4/c1-15-7-8-17(13-16(15)2)24-11-9-23(10-12-24)14-20-21-18-5-3-4-6-19(18)22-20/h3-8,13H,9-12,14H2,1-2H3,(H,21,22)	SAQMCVDGOIRQTC-UHFFFAOYSA-N	50150141	2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole::CHEMBL127257	Alpha-2A adrenergic receptor		>2000								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150141&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11301655	104038647		CHEMBL127257				ZINC13581153	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50808909	OCc1ccc(cc1Cl)N1CCN(Cc2nc3ccccc3[nH]2)CC1	InChI=1S/C19H21ClN4O/c20-16-11-15(6-5-14(16)13-25)24-9-7-23(8-10-24)12-19-21-17-3-1-2-4-18(17)22-19/h1-6,11,25H,7-10,12-13H2,(H,21,22)	HGMLOQOHAYKVJN-UHFFFAOYSA-N	50257036	CHEMBL4068924	Alpha-2A adrenergic receptor		>3000								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257036&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9863540	402360943							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50808910	C(C1Cc2ccccc2C1)N1CCN(CC1)c1ccc2OCCOc2c1	InChI=1S/C22H26N2O2/c1-2-4-19-14-17(13-18(19)3-1)16-23-7-9-24(10-8-23)20-5-6-21-22(15-20)26-12-11-25-21/h1-6,15,17H,7-14,16H2	CYPJMEGEBKHODC-UHFFFAOYSA-N	50257038	CHEMBL146556::S-18126	Alpha-2A adrenergic receptor		 249								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257038&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9884781	402360945							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50808911	NS(=O)(=O)c1ccc(cc1)N1CCN(CC[C@@H]2OCCc3ccccc23)CC1	InChI=1S/C21H27N3O3S/c22-28(25,26)19-7-5-18(6-8-19)24-14-12-23(13-15-24)11-9-21-20-4-2-1-3-17(20)10-16-27-21/h1-8,21H,9-16H2,(H2,22,25,26)/t21-/m0/s1	WNUQCGWXPNGORO-NRFANRHFSA-N	50051565	4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]-benzenesulfonamide::4-[4-(2-Isochroman-1-yl-ethyl)-piperazin-1-yl]-benzenesulfonamide::CHEMBL69759::Sonepiprazole	Alpha-2A adrenergic receptor		>1600								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051565&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133079	103948560		CHEMBL69759		980		ZINC03812548	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50808974	Clc1ccc(cc1)N1CCN(Cc2ccc3NC(=O)COc3c2)CC1	InChI=1S/C19H20ClN3O2/c20-15-2-4-16(5-3-15)23-9-7-22(8-10-23)12-14-1-6-17-18(11-14)25-13-19(24)21-17/h1-6,11H,7-10,12-13H2,(H,21,24)	UFFHNEZNXKJHFB-UHFFFAOYSA-N	50083342	7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one::CHEMBL346389	Alpha-2A adrenergic receptor		 411								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9885114	103983035		CHEMBL346389				ZINC53057273	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50809233	C[C@H]1C[C@@H](C)CN(CCCNC(=O)C2CCN(Cc3nc(oc3C)-c3c(C)cccc3Cl)CC2)C1	InChI=1S/C28H41ClN4O2/c1-19-15-20(2)17-33(16-19)12-6-11-30-27(34)23-9-13-32(14-10-23)18-25-22(4)35-28(31-25)26-21(3)7-5-8-24(26)29/h5,7-8,19-20,23H,6,9-18H2,1-4H3,(H,30,34)/t19-,20+	SHKOYYABTMCHBH-BGYRXZFFSA-N	50257088	CHEMBL4066784	Alpha-2A adrenergic receptor		 1416								ChEMBL	10.1021/acs.jmedchem.7b00561	10.7270/Q2DR2XXZ	28636348			He, S; Li, K; Lin, B; Hu, Z; Xiao, J; Hu, X; Wang, AQ; Xu, X; Ferrer, M; Southall, N; Zheng, W; Aubé, J; Schoenen, FJ; Marugan, JJ; Liang, TJ; Frankowski, KJ	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257088	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257088&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70789640	402360968							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
50886091	CCCC[S@@+]([O-])c1sc2nc(cc(-c3cnc(C)n3C)c2c1N)-c1nccs1	InChI=1S/C19H21N5OS3/c1-4-5-8-28(25)19-16(20)15-12(14-10-22-11(2)24(14)3)9-13(23-18(15)27-19)17-21-6-7-26-17/h6-7,9-10H,4-5,8,20H2,1-3H3/t28-/m1/s1	LKPKDKDBZLBUIC-MUUNZHRXSA-N	50266122	CHEMBL4070789	Alpha-2A adrenergic receptor			 900							ChEMBL	10.1021/acs.jmedchem.7b00271	10.7270/Q2280B21	28398755			Antczak, MI; Zhang, Y; Wang, C; Doran, J; Naidoo, J; Voruganti, S; Williams, NS; Markowitz, SD; Ready, JM	UT Southwestern Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266122&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			129281194	404857846							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51096347	NCCCCN(C[C@H]1Cc2ccccc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C23H32N4/c24-12-3-4-14-27(22-11-5-9-18-10-6-13-25-23(18)22)17-21-15-19-7-1-2-8-20(19)16-26-21/h1-2,6-8,10,13,21-22,26H,3-5,9,11-12,14-17,24H2/t21-,22+/m1/s1	MYCKNKHATQGHEV-YADHBBJMSA-N	50443541	CHEMBL3091687	Alpha-2A adrenergic receptor			 3700							ChEMBL	10.1021/acsmedchemlett.8b00030	10.7270/Q2Z89FZD	29795757			Tahirovic, YA; Truax, VM; Wilson, RJ; Jecs, E; Nguyen, HH; Miller, EJ; Kim, MB; Kuo, KM; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50443541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50443541&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345320	194941437		CHEMBL3091687					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51096351	Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl	InChI=1S/C27H21Br2ClN6O/c1-17-12-21(29)11-8-19(17)13-32-27(37)25-22(14-35-16-31-15-33-35)26(18-6-9-20(28)10-7-18)36(34-25)24-5-3-2-4-23(24)30/h2-12,15-16H,13-14H2,1H3,(H,32,37)	PZYIAIVLQMGYOR-UHFFFAOYSA-N	50310000	4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-N-(1-(4-bromophenyl)ethyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxamide::CHEMBL598769	Alpha-2A adrenergic receptor			>30000							ChEMBL	10.1021/acsmedchemlett.8b00030	10.7270/Q2Z89FZD	29795757			Tahirovic, YA; Truax, VM; Wilson, RJ; Jecs, E; Nguyen, HH; Miller, EJ; Kim, MB; Kuo, KM; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310000&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46230816	104164361		CHEMBL598769				ZINC49766409	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51096928	Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl	InChI=1S/C27H21Br2ClN6O/c1-17-12-21(29)11-8-19(17)13-32-27(37)25-22(14-35-16-31-15-33-35)26(18-6-9-20(28)10-7-18)36(34-25)24-5-3-2-4-23(24)30/h2-12,15-16H,13-14H2,1H3,(H,32,37)	PZYIAIVLQMGYOR-UHFFFAOYSA-N	50310000	4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-N-(1-(4-bromophenyl)ethyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxamide::CHEMBL598769	Alpha-2A adrenergic receptor			 5900							ChEMBL	10.1021/acsmedchemlett.8b00030	10.7270/Q2Z89FZD	29795757			Tahirovic, YA; Truax, VM; Wilson, RJ; Jecs, E; Nguyen, HH; Miller, EJ; Kim, MB; Kuo, KM; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310000&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46230816	104164361		CHEMBL598769				ZINC49766409	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51115920	CC(C)(C)OC(=O)NCCCCCCn1cc(CCCCN2CCC(CC2)c2ccc(cc2)-c2cc(cc3cc(ccc23)-c2ccc(cc2)C(F)(F)F)C(O)=O)nn1	InChI=1S/C46H54F3N5O4/c1-45(2,3)58-44(57)50-23-7-4-5-8-25-54-31-40(51-52-54)10-6-9-24-53-26-21-34(22-27-53)32-11-13-35(14-12-32)42-30-38(43(55)56)29-37-28-36(17-20-41(37)42)33-15-18-39(19-16-33)46(47,48)49/h11-20,28-31,34H,4-10,21-27H2,1-3H3,(H,50,57)(H,55,56)	JQWQITMAQMBUDN-UHFFFAOYSA-N	50456162	CHEMBL4217398	Alpha-2A adrenergic receptor		 5280								ChEMBL	10.1021/acs.jmedchem.8b00168	10.7270/Q2X069NH	29767967			Yu, J; Ciancetta, A; Dudas, S; Duca, S; Lottermoser, J; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456162&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			145973771	225147078							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51115925	NCCCCCCn1cc(CCCCN2CCC(CC2)c2ccc(cc2)-c2cc(cc3cc(ccc23)-c2ccc(cc2)C(F)(F)F)C(O)=O)nn1	InChI=1S/C41H46F3N5O2/c42-41(43,44)36-15-12-30(13-16-36)33-14-17-38-34(25-33)26-35(40(50)51)27-39(38)32-10-8-29(9-11-32)31-18-23-48(24-19-31)21-6-3-7-37-28-49(47-46-37)22-5-2-1-4-20-45/h8-17,25-28,31H,1-7,18-24,45H2,(H,50,51)	UFIMBHYPDHTMKA-UHFFFAOYSA-N	50456166	CHEMBL4216870	Alpha-2A adrenergic receptor		 28								ChEMBL	10.1021/acs.jmedchem.8b00168	10.7270/Q2X069NH	29767967			Yu, J; Ciancetta, A; Dudas, S; Duca, S; Lottermoser, J; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456166&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			126720252	225147082							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51100211	COc1cccc(c1)-c1ccc2CN(Cc3ccccc3)Cc2c1	InChI=1S/C22H21NO/c1-24-22-9-5-8-18(13-22)19-10-11-20-15-23(16-21(20)12-19)14-17-6-3-2-4-7-17/h2-13H,14-16H2,1H3	LGSGJWDXMWVXEB-UHFFFAOYSA-N	50370603	CHEMBL4167315::US10954217, Example 00225	Alpha-2A adrenergic receptor		 1685								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370603&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060720	160849705						ZINC64539249	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51100279	C(N1Cc2ccc(cc2C1)N1CCOCC1)c1ccccc1	InChI=1S/C19H22N2O/c1-2-4-16(5-3-1)13-20-14-17-6-7-19(12-18(17)15-20)21-8-10-22-11-9-21/h1-7,12H,8-11,13-15H2	LWZFMJZOOLLWCB-UHFFFAOYSA-N	50370662	CHEMBL4161503::US10954217, Example 00224	Alpha-2A adrenergic receptor		 2089								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370662&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060733	160849764	65324					ZINC73138787	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51100280	C(N1CCc2cc(ccc2C1)N1CCOCC1)c1ccccc1	InChI=1S/C20H24N2O/c1-2-4-17(5-3-1)15-21-9-8-18-14-20(7-6-19(18)16-21)22-10-12-23-13-11-22/h1-7,14H,8-13,15-16H2	KVANVFVDVNKGNH-UHFFFAOYSA-N	50370624	CHEMBL4169752::US10954217, Example 00234	Alpha-2A adrenergic receptor		 321								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370624&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132075278	160849726						ZINC49774262	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51100281	CN1CCN(CC1)c1ccc2CN(Cc2c1)C(=O)OCc1ccccc1	InChI=1S/C21H25N3O2/c1-22-9-11-23(12-10-22)20-8-7-18-14-24(15-19(18)13-20)21(25)26-16-17-5-3-2-4-6-17/h2-8,13H,9-12,14-16H2,1H3	UETLZTFBKJSNHG-UHFFFAOYSA-N	50370517	CHEMBL4163428::US10954217, Example 00227	Alpha-2A adrenergic receptor		 487								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370517&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060743	160849619						ZINC13584019	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51100282	CC(=C)CN1CCN(CC1)c1ccc2CCN(Cc2c1)C(=O)OCc1ccccc1	InChI=1S/C25H31N3O2/c1-20(2)17-26-12-14-27(15-13-26)24-9-8-22-10-11-28(18-23(22)16-24)25(29)30-19-21-6-4-3-5-7-21/h3-9,16H,1,10-15,17-19H2,2H3	BOIPWYRNMCLWCD-UHFFFAOYSA-N	50370625	CHEMBL4173095::US10954217, Example 00241	Alpha-2A adrenergic receptor		 876								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370625&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060763	160849727						ZINC49774436	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51100283	O=C(OCc1ccccc1)N1CCc2ccc(cc2C1)N1CCN(CC1)C1CCCC1	InChI=1S/C26H33N3O2/c30-26(31-20-21-6-2-1-3-7-21)29-13-12-22-10-11-25(18-23(22)19-29)28-16-14-27(15-17-28)24-8-4-5-9-24/h1-3,6-7,10-11,18,24H,4-5,8-9,12-17,19-20H2	UQSVESYMRYILGP-UHFFFAOYSA-N	50370623	CHEMBL4165863::US10954217, Example 00237	Alpha-2A adrenergic receptor		 506								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370623&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060776	160849725						ZINC28523132	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158593	CCS(=O)(=O)Nc1ccc2CCCC(c3c[nH]cn3)c2c1	InChI=1S/C15H19N3O2S/c1-2-21(19,20)18-12-7-6-11-4-3-5-13(14(11)8-12)15-9-16-10-17-15/h6-10,13,18H,2-5H2,1H3,(H,16,17)	BBMAPNYYKCUOGH-UHFFFAOYSA-N	50474632	CHEMBL327116	Alpha-2A adrenergic receptor		 23								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474632&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11347303	433941897							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158597	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2A adrenergic receptor		 275								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158601	CN(c1cccc2C(CCCc12)c1c[nH]cn1)S(C)(=O)=O	InChI=1S/C15H19N3O2S/c1-18(21(2,19)20)15-8-4-5-11-12(6-3-7-13(11)15)14-9-16-10-17-14/h4-5,8-10,12H,3,6-7H2,1-2H3,(H,16,17)	FVFGLHKVXSNGFR-UHFFFAOYSA-N	50474638	CHEMBL111463	Alpha-2A adrenergic receptor		 85								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474638&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9904606	433941903							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158613	CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)c1c[nH]cn1	InChI=1S/C14H17N3O3S/c1-21(19,20)17-14-11-4-2-3-10(12-7-15-8-16-12)9(11)5-6-13(14)18/h5-8,10,17-18H,2-4H2,1H3,(H,15,16)	RMRXQQJMELOBDK-UHFFFAOYSA-N	50474630	CHEMBL108804	Alpha-2A adrenergic receptor		 45								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474630&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9944409	433941895							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158619	CCS(=O)(=O)Nc1cccc2C(CCCc12)c1c[nH]cn1	InChI=1S/C15H19N3O2S/c1-2-21(19,20)18-14-8-4-5-11-12(14)6-3-7-13(11)15-9-16-10-17-15/h4-5,8-10,13,18H,2-3,6-7H2,1H3,(H,16,17)	DWUSTUPZNLOYSI-UHFFFAOYSA-N	50474633	CHEMBL111496	Alpha-2A adrenergic receptor		 132								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474633&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9926529	433941898							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158655	CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)C1=NCCN1	InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)	OQFCXJDXHCDLHX-UHFFFAOYSA-N	50118703	CHEMBL109783::N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl]-methanesulfonamide	Alpha-2A adrenergic receptor		 33								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118703&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4038180	104011967		CHEMBL109783		480		ZINC03995494	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158681	CS(=O)(=O)Nc1cccc2C(CCCc12)c1c[nH]cn1	InChI=1S/C14H17N3O2S/c1-20(18,19)17-13-7-3-4-10-11(13)5-2-6-12(10)14-8-15-9-16-14/h3-4,7-9,12,17H,2,5-6H2,1H3,(H,15,16)	FTWWLMPVXHMPNP-UHFFFAOYSA-N	50474671	CHEMBL111554	Alpha-2A adrenergic receptor		 105								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474671&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9904117	433941936							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158686	Nc1cccc2C(CCCc12)c1c[nH]cn1	InChI=1S/C13H15N3/c14-12-6-2-3-9-10(12)4-1-5-11(9)13-7-15-8-16-13/h2-3,6-8,11H,1,4-5,14H2,(H,15,16)	YBZJNASHMOQSEV-UHFFFAOYSA-N	50474654	CHEMBL323402	Alpha-2A adrenergic receptor		 72								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474654&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11183468	433941919							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158702	Oc1cccc2C(CCCc12)c1c[nH]cn1	InChI=1S/C13H14N2O/c16-13-6-2-3-9-10(4-1-5-11(9)13)12-7-14-8-15-12/h2-3,6-8,10,16H,1,4-5H2,(H,14,15)	URKMLGAUGBZDSY-UHFFFAOYSA-N	50471340	CHEMBL317912	Alpha-2A adrenergic receptor		 8.7								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471340&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10775000	433938605							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158711	FC(F)(F)C(=O)Nc1cccc2C(CCCc12)c1c[nH]cn1	InChI=1S/C15H14F3N3O/c16-15(17,18)14(22)21-12-6-2-3-9-10(12)4-1-5-11(9)13-7-19-8-20-13/h2-3,6-8,11H,1,4-5H2,(H,19,20)(H,21,22)	WNIQCRWLPXLGQD-UHFFFAOYSA-N	50474673	CHEMBL110751	Alpha-2A adrenergic receptor		 309								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474673&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9944467	433941938							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158715	FC(F)(F)CS(=O)(=O)Nc1cccc2C(CCCc12)c1c[nH]cn1	InChI=1S/C15H16F3N3O2S/c16-15(17,18)8-24(22,23)21-13-6-2-3-10-11(13)4-1-5-12(10)14-7-19-9-20-14/h2-3,6-7,9,12,21H,1,4-5,8H2,(H,19,20)	ZTIJSDAZRCWHKE-UHFFFAOYSA-N	50474666	CHEMBL321644	Alpha-2A adrenergic receptor		 955								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474666&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9950711	433941931							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158719	CCS(=O)(=O)Nc1cccc(Cc2cnc[nH]2)c1	InChI=1S/C12H15N3O2S/c1-2-18(16,17)15-11-5-3-4-10(6-11)7-12-8-13-9-14-12/h3-6,8-9,15H,2,7H2,1H3,(H,13,14)	ROUIPNDCVDWYEH-UHFFFAOYSA-N	50118705	ABT-866::CHEMBL326702::Ethanesulfonic acid [3-(1H-imidazol-4-ylmethyl)-phenyl]-amide::N-(3-((1H-imidazol-4-yl)methyl)phenyl)ethanesulfonamide::N-[3-(1H-imidazol-4-ylmethyl)-phenyl]ethanesulfonamide	Alpha-2A adrenergic receptor		 170								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118705&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9838192	104011969		CHEMBL326702				ZINC00008784	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158724	CC(=O)Nc1cccc2C(CCCc12)c1c[nH]cn1	InChI=1S/C15H17N3O/c1-10(19)18-14-7-3-4-11-12(14)5-2-6-13(11)15-8-16-9-17-15/h3-4,7-9,13H,2,5-6H2,1H3,(H,16,17)(H,18,19)	SXPWQXVCFMMCEE-UHFFFAOYSA-N	50474648	CHEMBL109848	Alpha-2A adrenergic receptor		 550								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474648&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9813756	433941913							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158736	CCS(=O)(=O)Nc1cccc2C(CCc12)c1c[nH]cn1	InChI=1S/C14H17N3O2S/c1-2-20(18,19)17-13-5-3-4-10-11(13)6-7-12(10)14-8-15-9-16-14/h3-5,8-9,12,17H,2,6-7H2,1H3,(H,15,16)	PIXGULLHGNRWSP-UHFFFAOYSA-N	50474660	CHEMBL111771	Alpha-2A adrenergic receptor		 98								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474660&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9879119	433941925							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51158776	COc1ccc(OC)c(c1)C(O)CN	InChI=1S/C10H15NO3/c1-13-7-3-4-10(14-2)8(5-7)9(12)6-11/h3-5,9,12H,6,11H2,1-2H3	VFRCNXKYZVQYLX-UHFFFAOYSA-N	50118702	2-Amino-1-(2,5-dimethoxy-phenyl)-ethanol::CHEMBL1076::DESGLYMIDODRINE::Orvaten::Proamatine	Alpha-2A adrenergic receptor		 1445								ChEMBL	10.1021/jm030551a	10.7270/Q2HD7ZD1	15163201			Altenbach, RJ; Khilevich, A; Kolasa, T; Rohde, JJ; Bhatia, PA; Patel, MV; Searle, XB; Yang, F; Bunnelle, WH; Tietje, K; Bayburt, EK; Carroll, WA; Meyer, MD; Henry, R; Buckner, SA; Kuk, J; Daza, AV; Milicic, IV; Cain, JC; Kang, CH; Ireland, LM; Carr, TL; Miller, TR; Hancock, AA; Nakane, M; Esbenshade, TA; Brune, ME; O'Neill, AB; Gauvin, DM; Katwala, SP; Holladay, MW; Brioni, JD; Sullivan, JP	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118702&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			43260	104011966	73248	CHEMBL1076				ZINC02001181	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162421	CC(Oc1ccccc1-c1ccccc1)C1=NCCO1	InChI=1S/C17H17NO2/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3	LMLZJQGDSZOQMG-UHFFFAOYSA-N	50476172	CHEMBL222591	Alpha-2A adrenergic receptor		 8128								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476172&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11448533	433943437							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162423	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2A adrenergic receptor					 589					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162424	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2A adrenergic receptor					 316					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162426	CC(Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)	IAIZHDGEGFGNMO-UHFFFAOYSA-N	50417347	CHEMBL385310	Alpha-2A adrenergic receptor		 46								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11371902	163366371		CHEMBL385310				ZINC13585567	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162435	CC(Oc1ccccc1-c1ccc(O)cc1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-10-11-19-17)21-16-5-3-2-4-15(16)13-6-8-14(20)9-7-13/h2-9,12,20H,10-11H2,1H3,(H,18,19)	LFMHROBTZOFVNB-UHFFFAOYSA-N	50476174	CHEMBL222798	Alpha-2A adrenergic receptor		 34								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476174&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11186227	433943439							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162440	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2A adrenergic receptor		 28								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162441	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2A adrenergic receptor					 372					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162443	CC(Oc1ccccc1-c1ccccc1)C1=NCCS1	InChI=1S/C17H17NOS/c1-13(17-18-11-12-20-17)19-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3	LTDPDISPKAJTKJ-UHFFFAOYSA-N	50476176	CHEMBL222592	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476176&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11278634	433943441							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162447	CC(Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)	IAIZHDGEGFGNMO-UHFFFAOYSA-N	50417347	CHEMBL385310	Alpha-2A adrenergic receptor					 76					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417347&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11371902	163366371		CHEMBL385310				ZINC13585567	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162452	CC(Oc1ccccc1-c1ccncc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-10-11-19-16)20-15-5-3-2-4-14(15)13-6-8-17-9-7-13/h2-9,12H,10-11H2,1H3,(H,18,19)	DPCJPADNVXIGHH-UHFFFAOYSA-N	50476181	CHEMBL442045	Alpha-2A adrenergic receptor		 282								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476181&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11380133	433943446							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162456	CC(Sc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2S/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	FYBWLLAUJOWVGO-UHFFFAOYSA-N	50476182	CHEMBL374954	Alpha-2A adrenergic receptor		 339								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476182&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11199593	433943447							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162458	CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1	InChI=1S/C17H17FN2O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	OOYTZYZXCMCMSZ-UHFFFAOYSA-N	50002903	CHEMBL223836	Alpha-2A adrenergic receptor		 15								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002903&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11211035	242056299		CHEMBL223836					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162460	Cl.C1CN=C(N1)C1OC1c1ccccc1-c1ccccc1	InChI=1S/C17H16N2O.ClH/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)15-16(20-15)17-18-10-11-19-17;/h1-9,15-16H,10-11H2,(H,18,19);1H	KSQSIGJRCSNCDY-UHFFFAOYSA-N	50476183	CHEMBL1204386	Alpha-2A adrenergic receptor		 1514								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476183&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52942940	433943448							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162466	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2A adrenergic receptor					 115					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162470	CC(Oc1ccccc1-c1cccc(N)c1)C1=NCCN1	InChI=1S/C17H19N3O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10,18H2,1H3,(H,19,20)	YVSAGYHRJDVYHG-UHFFFAOYSA-N	50476185	CHEMBL222371	Alpha-2A adrenergic receptor		 37								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476185&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11173568	433943450							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162472	CC(Oc1ccccc1-c1cccc(C)c1)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-6-5-7-15(12-13)16-8-3-4-9-17(16)21-14(2)18-19-10-11-20-18/h3-9,12,14H,10-11H2,1-2H3,(H,19,20)	OITKDPXYSUWTOJ-UHFFFAOYSA-N	50476173	CHEMBL222973	Alpha-2A adrenergic receptor		 51								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476173&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11277479	433943438							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162474	CC(Nc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H19N3/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13,20H,11-12H2,1H3,(H,18,19)	QPAIAAWBFFTOPZ-UHFFFAOYSA-N	50473619	CHEMBL130884	Alpha-2A adrenergic receptor					 389					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473619&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140033	433940884							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162477	C1CN=C(N1)C1OC1c1ccccc1-c1ccccc1	InChI=1S/C17H16N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)15-16(20-15)17-18-10-11-19-17/h1-9,15-16H,10-11H2,(H,18,19)	BTPMSDTWDTXFNP-UHFFFAOYSA-N	50476186	CHEMBL222933	Alpha-2A adrenergic receptor					 3467					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476186&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44421258	433943451					C00722		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162481	CC(Oc1ccccc1-c1ccccc1C)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-7-3-4-8-15(13)16-9-5-6-10-17(16)21-14(2)18-19-11-12-20-18/h3-10,14H,11-12H2,1-2H3,(H,19,20)	PJHALOKEQHBBKK-UHFFFAOYSA-N	50476188	CHEMBL223830	Alpha-2A adrenergic receptor		 47								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476188&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11300487	433943453							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162482	CC(Oc1ccccc1-c1cccs1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-8-9-17-15)18-13-6-3-2-5-12(13)14-7-4-10-19-14/h2-7,10-11H,8-9H2,1H3,(H,16,17)	LJLYHROZJUTILK-UHFFFAOYSA-N	50476178	CHEMBL223829	Alpha-2A adrenergic receptor		 17								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476178&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11360447	433943443							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162483	CC(Oc1ccccc1-c1ccccc1[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-10-11-19-17)23-16-9-5-3-7-14(16)13-6-2-4-8-15(13)20(21)22/h2-9,12H,10-11H2,1H3,(H,18,19)	JACPZVPJACONPS-UHFFFAOYSA-N	50476177	CHEMBL222138	Alpha-2A adrenergic receptor		 174								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476177&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11221758	433943442							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162487	CC(Oc1ccccc1-c1ccc(C)cc1)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-7-9-15(10-8-13)16-5-3-4-6-17(16)21-14(2)18-19-11-12-20-18/h3-10,14H,11-12H2,1-2H3,(H,19,20)	FVORBSYXXHDBGZ-UHFFFAOYSA-N	50476175	CHEMBL426900	Alpha-2A adrenergic receptor		 42								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476175&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11173544	433943440							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162490	CC(Oc1ccccc1-c1cccc(N)c1)C1=NCCN1	InChI=1S/C17H19N3O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10,18H2,1H3,(H,19,20)	YVSAGYHRJDVYHG-UHFFFAOYSA-N	50476185	CHEMBL222371	Alpha-2A adrenergic receptor					 257					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476185&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11173568	433943450							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162494	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2A adrenergic receptor		 138								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162499	C1CN=C(N1)C1OC1c1ccccc1-c1ccccc1	InChI=1S/C17H16N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)15-16(20-15)17-18-10-11-19-17/h1-9,15-16H,10-11H2,(H,18,19)	BTPMSDTWDTXFNP-UHFFFAOYSA-N	50476186	CHEMBL222933	Alpha-2A adrenergic receptor		 1230								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476186&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44421258	433943451					C00722		1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162500	CC(Nc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H19N3/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13,20H,11-12H2,1H3,(H,18,19)	QPAIAAWBFFTOPZ-UHFFFAOYSA-N	50473619	CHEMBL130884	Alpha-2A adrenergic receptor		 91								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473619&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140033	433940884							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162505	CC(Oc1ccccc1-c1cccs1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-8-9-17-15)18-13-6-3-2-5-12(13)14-7-4-10-19-14/h2-7,10-11H,8-9H2,1H3,(H,16,17)	LJLYHROZJUTILK-UHFFFAOYSA-N	50476178	CHEMBL223829	Alpha-2A adrenergic receptor					 42					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476178&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11360447	433943443							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162508	CC(Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)	NMSAVNXFCXMJJY-UHFFFAOYSA-N	50002904	CHEMBL222928	Alpha-2A adrenergic receptor		 60								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002904&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11361608	242056300		CHEMBL222928					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162509	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2A adrenergic receptor		 48								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162511	CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1	InChI=1S/C17H17FN2O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	OOYTZYZXCMCMSZ-UHFFFAOYSA-N	50002903	CHEMBL223836	Alpha-2A adrenergic receptor					 105					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002903&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11211035	242056299		CHEMBL223836					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162512	CC(Oc1ccccc1-c1ccccn1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-10-11-19-16)20-15-8-3-2-6-13(15)14-7-4-5-9-17-14/h2-9,12H,10-11H2,1H3,(H,18,19)	WRRWKIRSGSSXLV-UHFFFAOYSA-N	50476179	CHEMBL221989	Alpha-2A adrenergic receptor		 1202								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476179&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11380132	433943444							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162518	CC(Oc1ccccc1-c1ccccc1)C1=NCCC1	InChI=1S/C18H19NO/c1-14(17-11-7-13-19-17)20-18-12-6-5-10-16(18)15-8-3-2-4-9-15/h2-6,8-10,12,14H,7,11,13H2,1H3	XTQYZOCQEJTIQI-UHFFFAOYSA-N	50476184	CHEMBL222593	Alpha-2A adrenergic receptor		 8128								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476184&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11473729	433943449							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162524	CC(Oc1ccccc1-c1ccc(cc1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-10-11-19-17)23-16-5-3-2-4-15(16)13-6-8-14(9-7-13)20(21)22/h2-9,12H,10-11H2,1H3,(H,18,19)	ZMDCNVSZNFXVKI-UHFFFAOYSA-N	50476187	CHEMBL221523	Alpha-2A adrenergic receptor		 123								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476187&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11246610	433943452							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51162525	CC(Oc1ccccc1-c1ccccc1O)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-10-11-19-17)21-16-9-5-3-7-14(16)13-6-2-4-8-15(13)20/h2-9,12,20H,10-11H2,1H3,(H,18,19)	ACFBDYFNLOKRTR-UHFFFAOYSA-N	50476180	CHEMBL373830	Alpha-2A adrenergic receptor		 309								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476180&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11199581	433943445							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154665	CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1	InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	IPQYPIRIGUBUAF-MMVSWEMESA-N	50473224	CHEMBL296660	Alpha-2A adrenergic receptor		 28								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473224&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292232	433940489							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154670	C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1	InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PIAONGWBRPZERV-ZGUYJTEBSA-N	50473231	CHEMBL48341	Alpha-2A adrenergic receptor		 31								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473231&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9971924	433940496							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154671	CCC[C@H]1CCCC[C@@H]1NC1=NCCO1	InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	WDSZUSABLKNHCZ-QWRGUYRKSA-N	50473228	AGN-190837::CHEMBL297752	Alpha-2A adrenergic receptor					 1.6					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473228&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9815707	433940493							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154673	C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1	InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	RCLSMBSYDRCUSB-CEBMEMTBSA-N	50473226	CHEMBL297827	Alpha-2A adrenergic receptor		 16								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473226&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292386	433940491							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154674	C([C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)c1ccccc1	InChI=1S/C17H22N2O/c1-2-4-12(5-3-1)10-15-13-6-7-14(11-13)16(15)19-17-18-8-9-20-17/h1-5,13-16H,6-11H2,(H,18,19)/t13?,14?,15-,16+/m0/s1	NUMRIDYCRYHYHT-SSHXOBKSSA-N	50473229	CHEMBL295186	Alpha-2A adrenergic receptor		 14								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473229&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292385	433940494							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154676	CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1	InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	IPQYPIRIGUBUAF-MMVSWEMESA-N	50473224	CHEMBL296660	Alpha-2A adrenergic receptor					 11					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473224&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292232	433940489							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154682	C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1	InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PIAONGWBRPZERV-ZGUYJTEBSA-N	50473231	CHEMBL48341	Alpha-2A adrenergic receptor					 35					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473231&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9971924	433940496							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154683	C(Cc1ccccc1)[C@H]1CCCC[C@@H]1NC1=NCCO1	InChI=1S/C17H24N2O/c1-2-6-14(7-3-1)10-11-15-8-4-5-9-16(15)19-17-18-12-13-20-17/h1-3,6-7,15-16H,4-5,8-13H2,(H,18,19)/t15-,16+/m1/s1	MGQIWQQQIZXANT-CVEARBPZSA-N	50473230	CHEMBL47313	Alpha-2A adrenergic receptor		 1.4								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473230	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473230&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10707358	433940495							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154685	C([C@H]1CCCC[C@@H]1NC1=NCCO1)c1ccccc1	InChI=1S/C16H22N2O/c1-2-6-13(7-3-1)12-14-8-4-5-9-15(14)18-16-17-10-11-19-16/h1-3,6-7,14-15H,4-5,8-12H2,(H,17,18)/t14-,15+/m1/s1	YEPGXJIOCYXZAI-CABCVRRESA-N	50473232	CHEMBL50719	Alpha-2A adrenergic receptor		 21								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473232&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10848826	433940497							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154686	C1CN=C(N[C@H]2CCCC[C@@H]2c2ccccc2)O1	InChI=1S/C15H20N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)17-15-16-10-11-18-15/h1-3,6-7,13-14H,4-5,8-11H2,(H,16,17)/t13-,14+/m1/s1	NATLAODAVOGBDD-KGLIPLIRSA-N	50473225	CHEMBL297228	Alpha-2A adrenergic receptor		 18								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473225	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473225&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292381	433940490							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154689	C(C[C@H]1CCCC[C@@H]1NC1=NCCO1)Cc1ccccc1	InChI=1S/C18H26N2O/c1-2-7-15(8-3-1)9-6-11-16-10-4-5-12-17(16)20-18-19-13-14-21-18/h1-3,7-8,16-17H,4-6,9-14H2,(H,19,20)/t16-,17+/m1/s1	UDQDKOIZHDPWGR-SJORKVTESA-N	50473227	CHEMBL50720	Alpha-2A adrenergic receptor		 15								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473227	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473227&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10266032	433940492							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154694	CCC[C@H]1CCCC[C@@H]1NC1=NCCO1	InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	WDSZUSABLKNHCZ-QWRGUYRKSA-N	50473228	AGN-190837::CHEMBL297752	Alpha-2A adrenergic receptor		 3.0								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473228&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9815707	433940493							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51154696	C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1	InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	RCLSMBSYDRCUSB-CEBMEMTBSA-N	50473226	CHEMBL297827	Alpha-2A adrenergic receptor					 71					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473226&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292386	433940491							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155841	O=S1(=O)CCCc2cccc(NCC3=NCCN3)c12	InChI=1S/C13H17N3O2S/c17-19(18)8-2-4-10-3-1-5-11(13(10)19)16-9-12-14-6-7-15-12/h1,3,5,16H,2,4,6-9H2,(H,14,15)	WAXAHQBOIDNYSY-UHFFFAOYSA-N	50473670	CHEMBL70740	Alpha-2A adrenergic receptor		 794								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473670&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10923927	433940935							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155844	CSc1ccc(F)cc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	BCCMUPQZPVRDCD-UHFFFAOYSA-N	50473672	CHEMBL72768	Alpha-2A adrenergic receptor					 25					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473672&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140347	433940937							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155846	CSc1c(F)cccc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-11-8(12)3-2-4-9(11)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	QJUBRJKAGWBYDR-UHFFFAOYSA-N	50473669	CHEMBL70692	Alpha-2A adrenergic receptor		 166								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473669&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140345	433940934							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155858	CSc1cc(F)ccc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	XBBHVMXFPPVGMX-UHFFFAOYSA-N	50473678	CHEMBL306792	Alpha-2A adrenergic receptor		 59								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473678&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11097789	433940943							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155863	CSc1ccc(C)cc1NCC1=NCCN1	InChI=1S/C12H17N3S/c1-9-3-4-11(16-2)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	ZVVQFUFKMNLNCB-UHFFFAOYSA-N	50473677	CHEMBL72441	Alpha-2A adrenergic receptor					 25					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473677&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10934575	433940942							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155870	CCS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C12H17N3O2S/c1-2-18(16,17)11-6-4-3-5-10(11)15-9-12-13-7-8-14-12/h3-6,15H,2,7-9H2,1H3,(H,13,14)	ZZCOHDYKTIEHEF-UHFFFAOYSA-N	50473668	CHEMBL70973	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473668&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10221004	433940933							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155872	CS(=O)(=O)c1cc(Cl)ccc1NCC1=NCCN1	InChI=1S/C11H14ClN3O2S/c1-18(16,17)10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	RNPCNKHTEISXAL-UHFFFAOYSA-N	50473676	CHEMBL70563	Alpha-2A adrenergic receptor		 5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473676&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10916464	433940941							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155875	COc1ccc(c(NCC2=NCCN2)c1)S(C)(=O)=O	InChI=1S/C12H17N3O3S/c1-18-9-3-4-11(19(2,16)17)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	WURKOHONKFWQNR-UHFFFAOYSA-N	50218568	CHEMBL71001	Alpha-2A adrenergic receptor		 3631								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9817256	377007550		CHEMBL71001					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155879	CS(=O)(=O)c1cc(F)ccc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	DLSVKFMVCHCZLY-UHFFFAOYSA-N	50473664	CHEMBL70326	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473664&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11079593	433940929							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155882	CS(=O)(=O)c1ccc(cc1NCC1=NCCN1)C(F)(F)F	InChI=1S/C12H14F3N3O2S/c1-21(19,20)10-3-2-8(12(13,14)15)6-9(10)18-7-11-16-4-5-17-11/h2-3,6,18H,4-5,7H2,1H3,(H,16,17)	NEAKCLFZBLSGMR-UHFFFAOYSA-N	50473680	CHEMBL302698	Alpha-2A adrenergic receptor		<7943								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473680&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11059195	433940945							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155887	COc1ccc(SC)c(NCC2=NCCN2)c1	InChI=1S/C12H17N3OS/c1-16-9-3-4-11(17-2)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	NMTCRDZBJDXVCH-UHFFFAOYSA-N	50473682	CHEMBL70691	Alpha-2A adrenergic receptor					 446					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473682&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11098175	433940947							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155893	CS(=O)(=O)c1ccc(F)cc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	YYHDOUOUAFMQDK-UHFFFAOYSA-N	50473684	CHEMBL74467	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473684&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10199335	433940949							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155895	CSc1ccc(F)cc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	BCCMUPQZPVRDCD-UHFFFAOYSA-N	50473672	CHEMBL72768	Alpha-2A adrenergic receptor		 18								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473672&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140347	433940937							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155910	CSc1ccc(cc1NCC1=NCCN1)C(F)(F)F	InChI=1S/C12H14F3N3S/c1-19-10-3-2-8(12(13,14)15)6-9(10)18-7-11-16-4-5-17-11/h2-3,6,18H,4-5,7H2,1H3,(H,16,17)	GBSLCSDIFSTSOZ-UHFFFAOYSA-N	50473683	CHEMBL72724	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473683&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11034737	433940948							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155911	Cl.CCSc1ccccc1NCC1=NCCN1	InChI=1S/C12H17N3S/c1-2-16-11-6-4-3-5-10(11)15-9-12-13-7-8-14-12/h3-6,15H,2,7-9H2,1H3,(H,13,14)	MZDQVKPPFWIZIL-UHFFFAOYSA-N	50473681	CHEMBL540035	Alpha-2A adrenergic receptor		 81								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473681&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45264638	433940946							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155922	CS(=O)(=O)c1c(F)cccc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)11-8(12)3-2-4-9(11)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	FFVMPJRYEFKURT-UHFFFAOYSA-N	50473667	CHEMBL419448	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473667&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11090351	433940932							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155923	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor		 16								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155928	Cl.CC(C)Sc1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3S/c1-10(2)17-12-6-4-3-5-11(12)16-9-13-14-7-8-15-13/h3-6,10,16H,7-9H2,1-2H3,(H,14,15)	RREJZKOLYMUBNO-UHFFFAOYSA-N	50473663	CHEMBL553276	Alpha-2A adrenergic receptor					 417					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473663&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45260704	433940928							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155929	CS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3O2S/c1-17(15,16)10-5-3-2-4-9(10)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	MCTRZCCYVQDHLM-UHFFFAOYSA-N	50218593	CHEMBL117094	Alpha-2A adrenergic receptor		 5623								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218593&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816461	377007553		CHEMBL117094					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155931	Cl.C[S+]([O-])c1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3OS.ClH/c1-16(15)10-5-3-2-4-9(10)14-8-11-12-6-7-13-11;/h2-5,14H,6-8H2,1H3,(H,12,13);1H	CLJWUQUYJYUFLN-UHFFFAOYSA-N	50473666	CHEMBL542402	Alpha-2A adrenergic receptor		 977								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473666&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45260703	433940931							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155946	Cl.C[S+]([O-])c1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3OS.ClH/c1-16(15)10-5-3-2-4-9(10)14-8-11-12-6-7-13-11;/h2-5,14H,6-8H2,1H3,(H,12,13);1H	CLJWUQUYJYUFLN-UHFFFAOYSA-N	50473666	CHEMBL542402	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473666&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45260703	433940931							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155949	CS(=O)(=O)c1ccc(cc1NCC1=NCCN1)C(F)(F)F	InChI=1S/C12H14F3N3O2S/c1-21(19,20)10-3-2-8(12(13,14)15)6-9(10)18-7-11-16-4-5-17-11/h2-3,6,18H,4-5,7H2,1H3,(H,16,17)	NEAKCLFZBLSGMR-UHFFFAOYSA-N	50473680	CHEMBL302698	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473680&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11059195	433940945							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155951	CSc1ccc(Cl)cc1NCC1=NCCN1	InChI=1S/C11H14ClN3S/c1-16-10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	ZHDIISZEXUGDAJ-UHFFFAOYSA-N	50473665	CHEMBL70751	Alpha-2A adrenergic receptor					 6.3					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473665&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11109088	433940930							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155954	CS(=O)(=O)c1cccc(F)c1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)9-4-2-3-8(12)11(9)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	FAINGUBYHMRNKU-UHFFFAOYSA-N	50473675	CHEMBL74114	Alpha-2A adrenergic receptor		 871								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473675&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11058166	433940940							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155958	COc1ccc(SC)c(NCC2=NCCN2)c1	InChI=1S/C12H17N3OS/c1-16-9-3-4-11(17-2)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	NMTCRDZBJDXVCH-UHFFFAOYSA-N	50473682	CHEMBL70691	Alpha-2A adrenergic receptor					 447					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473682&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11098175	433940947							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155964	COc1ccc(c(NCC2=NCCN2)c1)S(C)(=O)=O	InChI=1S/C12H17N3O3S/c1-18-9-3-4-11(19(2,16)17)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	WURKOHONKFWQNR-UHFFFAOYSA-N	50218568	CHEMBL71001	Alpha-2A adrenergic receptor					 3311					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9817256	377007550		CHEMBL71001					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155966	CS(=O)(=O)c1ccc(Cl)cc1NCC1=NCCN1	InChI=1S/C11H14ClN3O2S/c1-18(16,17)10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	VFLQPKLTPYIDEK-UHFFFAOYSA-N	50473674	CHEMBL70634	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473674&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9947861	433940939							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155969	CS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3O2S/c1-17(15,16)10-5-3-2-4-9(10)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	MCTRZCCYVQDHLM-UHFFFAOYSA-N	50218593	CHEMBL117094	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218593&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816461	377007553		CHEMBL117094					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155970	CS(=O)(=O)c1c(F)cccc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)11-8(12)3-2-4-9(11)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	FFVMPJRYEFKURT-UHFFFAOYSA-N	50473667	CHEMBL419448	Alpha-2A adrenergic receptor		<7943								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473667&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11090351	433940932							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155971	Cc1ccc(c(NCC2=NCCN2)c1)S(C)(=O)=O	InChI=1S/C12H17N3O2S/c1-9-3-4-11(18(2,16)17)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	NIILDWZATWLEEZ-UHFFFAOYSA-N	50473671	CHEMBL71479	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473671&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10221005	433940936							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155981	CS(=O)(=O)c1cc(F)ccc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	DLSVKFMVCHCZLY-UHFFFAOYSA-N	50473664	CHEMBL70326	Alpha-2A adrenergic receptor		 398								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473664&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11079593	433940929							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155987	Cl.CCCS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3O2S/c1-2-9-19(17,18)12-6-4-3-5-11(12)16-10-13-14-7-8-15-13/h3-6,16H,2,7-10H2,1H3,(H,14,15)	DURATMICCIEKQS-UHFFFAOYSA-N	50473679	CHEMBL554416	Alpha-2A adrenergic receptor		<7943								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473679&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			22493245	433940944							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155988	COc1ccc(SC)c(NCC2=NCCN2)c1	InChI=1S/C12H17N3OS/c1-16-9-3-4-11(17-2)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	NMTCRDZBJDXVCH-UHFFFAOYSA-N	50473682	CHEMBL70691	Alpha-2A adrenergic receptor		 219								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473682&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11098175	433940947							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155993	Cl.CCSc1ccccc1NCC1=NCCN1	InChI=1S/C12H17N3S/c1-2-16-11-6-4-3-5-10(11)15-9-12-13-7-8-14-12/h3-6,15H,2,7-9H2,1H3,(H,13,14)	MZDQVKPPFWIZIL-UHFFFAOYSA-N	50473681	CHEMBL540035	Alpha-2A adrenergic receptor					 251					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473681&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45264638	433940946							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155994	CSc1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3S/c1-15-10-5-3-2-4-9(10)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	YGIWTZGEYHABOR-UHFFFAOYSA-N	50421580	CHEMBL117248	Alpha-2A adrenergic receptor					 40					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421580&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11108001	164150455		CHEMBL117248				ZINC13473754	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155995	CSc1cc(F)ccc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	XBBHVMXFPPVGMX-UHFFFAOYSA-N	50473678	CHEMBL306792	Alpha-2A adrenergic receptor					 316					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473678&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11097789	433940943							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155999	CSc1ccc(Cl)cc1NCC1=NCCN1	InChI=1S/C11H14ClN3S/c1-16-10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	ZHDIISZEXUGDAJ-UHFFFAOYSA-N	50473665	CHEMBL70751	Alpha-2A adrenergic receptor		 42								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473665&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11109088	433940930							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156010	CSc1ccc(C)cc1NCC1=NCCN1	InChI=1S/C12H17N3S/c1-9-3-4-11(16-2)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	ZVVQFUFKMNLNCB-UHFFFAOYSA-N	50473677	CHEMBL72441	Alpha-2A adrenergic receptor		 63								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473677&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10934575	433940942							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156014	CS(=O)(=O)c1cc(Cl)ccc1NCC1=NCCN1	InChI=1S/C11H14ClN3O2S/c1-18(16,17)10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	RNPCNKHTEISXAL-UHFFFAOYSA-N	50473676	CHEMBL70563	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473676&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10916464	433940941							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156023	O=S1(=O)CCCc2cccc(NCC3=NCCN3)c12	InChI=1S/C13H17N3O2S/c17-19(18)8-2-4-10-3-1-5-11(13(10)19)16-9-12-14-6-7-15-12/h1,3,5,16H,2,4,6-9H2,(H,14,15)	WAXAHQBOIDNYSY-UHFFFAOYSA-N	50473670	CHEMBL70740	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473670&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10923927	433940935							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156034	CSc1c(F)cccc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-11-8(12)3-2-4-9(11)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	QJUBRJKAGWBYDR-UHFFFAOYSA-N	50473669	CHEMBL70692	Alpha-2A adrenergic receptor					 100					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473669&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140345	433940934							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156040	CS(=O)(=O)c1ccc(F)cc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	YYHDOUOUAFMQDK-UHFFFAOYSA-N	50473684	CHEMBL74467	Alpha-2A adrenergic receptor		 4467								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473684&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10199335	433940949							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156066	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2A adrenergic receptor					 3.3					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156074	Cc1ccc(c(NCC2=NCCN2)c1)S(C)(=O)=O	InChI=1S/C12H17N3O2S/c1-9-3-4-11(18(2,16)17)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	NIILDWZATWLEEZ-UHFFFAOYSA-N	50473671	CHEMBL71479	Alpha-2A adrenergic receptor		 3890								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473671&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10221005	433940936							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156077	COc1ccc(c(NCC2=NCCN2)c1)S(C)(=O)=O	InChI=1S/C12H17N3O3S/c1-18-9-3-4-11(19(2,16)17)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	WURKOHONKFWQNR-UHFFFAOYSA-N	50218568	CHEMBL71001	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218568&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9817256	377007550		CHEMBL71001					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156080	CS(=O)(=O)c1ccc(Cl)cc1NCC1=NCCN1	InChI=1S/C11H14ClN3O2S/c1-18(16,17)10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	VFLQPKLTPYIDEK-UHFFFAOYSA-N	50473674	CHEMBL70634	Alpha-2A adrenergic receptor		<7943								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473674&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9947861	433940939							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156091	CC(C)S(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3O2S/c1-10(2)19(17,18)12-6-4-3-5-11(12)16-9-13-14-7-8-15-13/h3-6,10,16H,7-9H2,1-2H3,(H,14,15)	XDUYFOWMTMCCEI-UHFFFAOYSA-N	50473673	CHEMBL74071	Alpha-2A adrenergic receptor		 2951								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473673&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11811395	433940938							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156092	Cl.CC(C)Sc1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3S/c1-10(2)17-12-6-4-3-5-11(12)16-9-13-14-7-8-15-13/h3-6,10,16H,7-9H2,1-2H3,(H,14,15)	RREJZKOLYMUBNO-UHFFFAOYSA-N	50473663	CHEMBL553276	Alpha-2A adrenergic receptor		 81								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473663&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45260704	433940928							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156104	CSc1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3S/c1-15-10-5-3-2-4-9(10)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	YGIWTZGEYHABOR-UHFFFAOYSA-N	50421580	CHEMBL117248	Alpha-2A adrenergic receptor		 48								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421580&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11108001	164150455		CHEMBL117248				ZINC13473754	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156108	CSc1ccc(cc1NCC1=NCCN1)C(F)(F)F	InChI=1S/C12H14F3N3S/c1-19-10-3-2-8(12(13,14)15)6-9(10)18-7-11-16-4-5-17-11/h2-3,6,18H,4-5,7H2,1H3,(H,16,17)	GBSLCSDIFSTSOZ-UHFFFAOYSA-N	50473683	CHEMBL72724	Alpha-2A adrenergic receptor		 200								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473683&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11034737	433940948							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156110	CS(=O)(=O)c1cccc(F)c1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)9-4-2-3-8(12)11(9)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	FAINGUBYHMRNKU-UHFFFAOYSA-N	50473675	CHEMBL74114	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473675&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11058166	433940940							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156111	CC(C)S(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3O2S/c1-10(2)19(17,18)12-6-4-3-5-11(12)16-9-13-14-7-8-15-13/h3-6,10,16H,7-9H2,1-2H3,(H,14,15)	XDUYFOWMTMCCEI-UHFFFAOYSA-N	50473673	CHEMBL74071	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473673&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11811395	433940938							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156114	CCS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C12H17N3O2S/c1-2-18(16,17)11-6-4-3-5-10(11)15-9-12-13-7-8-14-12/h3-6,15H,2,7-9H2,1H3,(H,13,14)	ZZCOHDYKTIEHEF-UHFFFAOYSA-N	50473668	CHEMBL70973	Alpha-2A adrenergic receptor		 1318								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473668&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10221004	433940933							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51156115	CS(=O)(=O)Nc1ccc(F)c(c1)[C@@H](O)CN	InChI=1S/C9H13FN2O3S/c1-16(14,15)12-6-2-3-8(10)7(4-6)9(13)5-11/h2-4,9,12-13H,5,11H2,1H3/t9-/m0/s1	XYLJNMCMDOOJRW-VIFPVBQESA-N	50000215	NS-49	Alpha-2A adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000215&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9838763	242055755							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150919	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(c(OC)c1)[N+]([O-])=O	InChI=1S/C37H42N4O6/c1-25-32(34(33(26(2)39-25)36(43)47-4)27-16-17-30(41(44)45)31(24-27)46-3)35(42)38-20-11-21-40-22-18-37(19-23-40,28-12-7-5-8-13-28)29-14-9-6-10-15-29/h5-10,12-17,24,34,43H,11,18-23H2,1-4H3,(H,38,42)/b36-33+	BTYBILKFYYEYRM-PKUSAGTQSA-N	50471685	CHEMBL313160	Alpha-2A adrenergic receptor		 631								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471685&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10508332	433938950							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150921	CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C35H39N5O4/c1-24-30(33(36)41)32(26-14-16-29(17-15-26)40(43)44)31(25(2)38-24)34(42)37-20-9-21-39-22-18-35(19-23-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17,30,32H,9,18-23H2,1-2H3,(H2,36,41)(H,37,42)	JWIXQLYEPDLLJM-UHFFFAOYSA-N	50068828	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL279436	Alpha-2A adrenergic receptor		 151								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068828&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53978088	103963006		CHEMBL279436				ZINC28759508	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150924	CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C35H39N5O4/c1-24-30(33(36)41)32(26-14-16-29(17-15-26)40(43)44)31(25(2)38-24)34(42)37-20-9-21-39-22-18-35(19-23-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17,30,32H,9,18-23H2,1-2H3,(H2,36,41)(H,37,42)	JWIXQLYEPDLLJM-UHFFFAOYSA-N	50068828	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL279436	Alpha-2A adrenergic receptor		 151								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068828&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53978088	103963006		CHEMBL279436				ZINC28759508	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150927	CNC(=O)C1=C(C)NC(C)=C(C1c1ccc2OCOc2c1)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C37H42N4O4/c1-25-32(35(42)38-3)34(27-15-16-30-31(23-27)45-24-44-30)33(26(2)40-25)36(43)39-19-10-20-41-21-17-37(18-22-41,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-16,23,34,40H,10,17-22,24H2,1-3H3,(H,38,42)(H,39,43)	GJSIQLZDGMIVKC-UHFFFAOYSA-N	50471689	CHEMBL88628	Alpha-2A adrenergic receptor		 2089								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471689&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11801828	433938954							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150935	CCC1=C(C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(CC)N1)c1ccc(cc1)[N+]([O-])=O)C(N)=O	InChI=1S/C37H43N5O4/c1-3-30-33(35(38)43)32(26-16-18-29(19-17-26)42(45)46)34(31(4-2)40-30)36(44)39-22-11-23-41-24-20-37(21-25-41,27-12-7-5-8-13-27)28-14-9-6-10-15-28/h5-10,12-19,32,40H,3-4,11,20-25H2,1-2H3,(H2,38,43)(H,39,44)	JEZMYAZTGNMODX-UHFFFAOYSA-N	50471694	CHEMBL91550	Alpha-2A adrenergic receptor		 355								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471694&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9895326	433938959							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150947	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc2OCOc2c1	InChI=1S/C37H41N3O5/c1-25-32(34(33(26(2)39-25)36(42)43-3)27-15-16-30-31(23-27)45-24-44-30)35(41)38-19-10-20-40-21-17-37(18-22-40,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-16,23,34,42H,10,17-22,24H2,1-3H3,(H,38,41)/b36-33+	WJRKWJSQVYFSFK-PKUSAGTQSA-N	50471697	CHEMBL91415	Alpha-2A adrenergic receptor		 1122								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471697&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10531766	433938962							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150952	CC(=O)C1=C(C)NC(C)=C(C1c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H40N4O4/c1-25-32(27(3)41)34(28-15-17-31(18-16-28)40(43)44)33(26(2)38-25)35(42)37-21-10-22-39-23-19-36(20-24-39,29-11-6-4-7-12-29)30-13-8-5-9-14-30/h4-9,11-18,34,38H,10,19-24H2,1-3H3,(H,37,42)	SCZDZQFTMOOIDO-UHFFFAOYSA-N	50471698	CHEMBL89685	Alpha-2A adrenergic receptor		 603								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471698&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9851486	433938963							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150955	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(C)cc1	InChI=1S/C37H43N3O3/c1-26-16-18-29(19-17-26)34-32(27(2)39-28(3)33(34)36(42)43-4)35(41)38-22-11-23-40-24-20-37(21-25-40,30-12-7-5-8-13-30)31-14-9-6-10-15-31/h5-10,12-19,34,42H,11,20-25H2,1-4H3,(H,38,41)/b36-33+	CACGBSVXIXSELL-PKUSAGTQSA-N	50471696	CHEMBL315914	Alpha-2A adrenergic receptor		 1288								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471696&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10627021	433938961							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150966	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)C#N	InChI=1S/C37H40N4O3/c1-26-32(34(29-17-15-28(25-38)16-18-29)33(27(2)40-26)36(43)44-3)35(42)39-21-10-22-41-23-19-37(20-24-41,30-11-6-4-7-12-30)31-13-8-5-9-14-31/h4-9,11-18,34,43H,10,19-24H2,1-3H3,(H,39,42)/b36-33+	OUDWCNZTASZGHL-PKUSAGTQSA-N	50471692	CHEMBL89243	Alpha-2A adrenergic receptor		 759								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471692&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10674896	433938957							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150968	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc2ccccc2c1	InChI=1S/C40H43N3O3/c1-28-35(37(36(29(2)42-28)39(45)46-3)32-20-19-30-13-10-11-14-31(30)27-32)38(44)41-23-12-24-43-25-21-40(22-26-43,33-15-6-4-7-16-33)34-17-8-5-9-18-34/h4-11,13-20,27,37,45H,12,21-26H2,1-3H3,(H,41,44)/b39-36+	OBVUZKZJWYCTTA-WQBMDMGNSA-N	50471693	CHEMBL92322	Alpha-2A adrenergic receptor		 1585								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471693&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10508016	433938958							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150977	CO\C(O)=C1\C(C(C(=O)N(C)CCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C37H42N4O5/c1-26-32(34(33(27(2)38-26)36(43)46-4)28-16-18-31(19-17-28)41(44)45)35(42)39(3)22-11-23-40-24-20-37(21-25-40,29-12-7-5-8-13-29)30-14-9-6-10-15-30/h5-10,12-19,34,43H,11,20-25H2,1-4H3/b36-33+	AHCOOGMIZVMEKD-PKUSAGTQSA-N	50471702	CHEMBL88448	Alpha-2A adrenergic receptor		 676								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471702&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10603951	433938967							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150978	CC1=C(C#N)C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N1)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C35H37N5O3/c1-25-31(24-36)33(27-14-16-30(17-15-27)40(42)43)32(26(2)38-25)34(41)37-20-9-21-39-22-18-35(19-23-39,28-10-5-3-6-11-28)29-12-7-4-8-13-29/h3-8,10-17,33,38H,9,18-23H2,1-2H3,(H,37,41)	JAXIKFIDJJLTAT-UHFFFAOYSA-N	50471699	CHEMBL327775	Alpha-2A adrenergic receptor		 631								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471699&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10626982	433938964							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150981	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2A adrenergic receptor		 1202								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150983	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)c2ccccc2)=C(C)N=C1C)c1ccc(Cl)c(c1)[N+]([O-])=O	InChI=1S/C30H35ClN4O5/c1-19-26(29(36)32-14-7-15-34-16-12-22(13-17-34)21-8-5-4-6-9-21)28(27(20(2)33-19)30(37)40-3)23-10-11-24(31)25(18-23)35(38)39/h4-6,8-11,18,22,28,37H,7,12-17H2,1-3H3,(H,32,36)/b30-27+	XETGFITVYCWVGB-KDJFERLWSA-N	50471684	CHEMBL327931	Alpha-2A adrenergic receptor		 110								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471684&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10769331	433938949							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150984	CNC(=O)C1=C(C)NC(C)=C(C1c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H41N5O4/c1-25-31(34(42)37-3)33(27-15-17-30(18-16-27)41(44)45)32(26(2)39-25)35(43)38-21-10-22-40-23-19-36(20-24-40,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,33,39H,10,19-24H2,1-3H3,(H,37,42)(H,38,43)	YMSCVVXGMWMEMM-UHFFFAOYSA-N	50471703	CHEMBL284103	Alpha-2A adrenergic receptor		 398								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471703&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10841387	433938968							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150988	CN(C)C(=O)C1=C(C)NC(C)=C(C1c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C37H43N5O4/c1-26-32(34(28-16-18-31(19-17-28)42(45)46)33(27(2)39-26)36(44)40(3)4)35(43)38-22-11-23-41-24-20-37(21-25-41,29-12-7-5-8-13-29)30-14-9-6-10-15-30/h5-10,12-19,34,39H,11,20-25H2,1-4H3,(H,38,43)	SNLNBLRAKFOCGE-UHFFFAOYSA-N	50471704	CHEMBL315392	Alpha-2A adrenergic receptor		 955								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471704&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10508132	433938969							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150991	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)	VCKUSRYTPJJLNI-UHFFFAOYSA-N	50033111	1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine	Alpha-2A adrenergic receptor		 550								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033111&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TZN	4O3F,4O33	5401	103941452	9445	CHEMBL611	DB01162	7302	C07127	ZINC01271441	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51150999	CC(=O)C1=C(C)NC(C)=C(C1c1ccc2OCOc2c1)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C37H41N3O4/c1-25-33(27(3)41)35(28-15-16-31-32(23-28)44-24-43-31)34(26(2)39-25)36(42)38-19-10-20-40-21-17-37(18-22-40,29-11-6-4-7-12-29)30-13-8-5-9-14-30/h4-9,11-16,23,35,39H,10,17-22,24H2,1-3H3,(H,38,42)	FOGMNVRCPAJQDZ-UHFFFAOYSA-N	50471690	CHEMBL88388	Alpha-2A adrenergic receptor		 955								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471690&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10507651	433938955							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151022	CC(C)C1=C(C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(N1)C(C)C)c1ccc(cc1)[N+]([O-])=O)C(N)=O	InChI=1S/C39H47N5O4/c1-26(2)35-33(37(40)45)32(28-16-18-31(19-17-28)44(47)48)34(36(42-35)27(3)4)38(46)41-22-11-23-43-24-20-39(21-25-43,29-12-7-5-8-13-29)30-14-9-6-10-15-30/h5-10,12-19,26-27,32,42H,11,20-25H2,1-4H3,(H2,40,45)(H,41,46)	OXDMFICMRHFYME-UHFFFAOYSA-N	50471705	CHEMBL313953	Alpha-2A adrenergic receptor		 676								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471705&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10818003	433938970							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151023	CC1=C(C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N1)c1ccc2OCOc2c1)C(N)=O	InChI=1S/C36H40N4O4/c1-24-31(34(37)41)33(26-14-15-29-30(22-26)44-23-43-29)32(25(2)39-24)35(42)38-18-9-19-40-20-16-36(17-21-40,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-15,22,33,39H,9,16-21,23H2,1-2H3,(H2,37,41)(H,38,42)	MWOOWQMUFWOYRV-UHFFFAOYSA-N	50471691	CHEMBL312871	Alpha-2A adrenergic receptor		 501								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471691&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10651080	433938956							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151028	CO\C(O)=C1\C(C(C(=O)NCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C35H38N4O5/c1-24-30(32(31(25(2)37-24)34(41)44-3)26-14-16-29(17-15-26)39(42)43)33(40)36-20-23-38-21-18-35(19-22-38,27-10-6-4-7-11-27)28-12-8-5-9-13-28/h4-17,32,41H,18-23H2,1-3H3,(H,36,40)/b34-31+	YQTAOHSPORUWMC-WUVHBKSUSA-N	50471706	CHEMBL91956	Alpha-2A adrenergic receptor		 447								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471706&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10531532	433938971							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151029	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C30H36N4O5/c1-20-26(28(27(21(2)32-20)30(36)39-3)24-10-12-25(13-11-24)34(37)38)29(35)31-16-7-17-33-18-14-23(15-19-33)22-8-5-4-6-9-22/h4-6,8-13,23,28,36H,7,14-19H2,1-3H3,(H,31,35)/b30-27+	KADUIVAIJUZKJS-KDJFERLWSA-N	50471700	CHEMBL91022	Alpha-2A adrenergic receptor		 275								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471700&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9828476	433938965							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151033	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(Cl)cc1	InChI=1S/C36H40ClN3O3/c1-25-31(33(27-15-17-30(37)18-16-27)32(26(2)39-25)35(42)43-3)34(41)38-21-10-22-40-23-19-36(20-24-40,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,33,42H,10,19-24H2,1-3H3,(H,38,41)/b35-32+	WFSGQIXIGIQILN-LVYIWIAJSA-N	50471695	CHEMBL314960	Alpha-2A adrenergic receptor		 2138								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471695&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10793665	433938960							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151042	CO\C(O)=C1\C(C(C(=O)NCCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C37H42N4O5/c1-26-32(34(33(27(2)39-26)36(43)46-3)28-16-18-31(19-17-28)41(44)45)35(42)38-22-10-11-23-40-24-20-37(21-25-40,29-12-6-4-7-13-29)30-14-8-5-9-15-30/h4-9,12-19,34,43H,10-11,20-25H2,1-3H3,(H,38,42)/b36-33+	SZTNZABXFFPBMM-PKUSAGTQSA-N	50471686	CHEMBL284470	Alpha-2A adrenergic receptor		 646								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471686&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10793963	433938951							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155412	C1C([C@@H]2CN=CN2)[C@]11CCc2ccccc2C1	InChI=1S/C15H18N2/c1-2-4-12-7-15(6-5-11(12)3-1)8-13(15)14-9-16-10-17-14/h1-4,10,13-14H,5-9H2,(H,16,17)/t13?,14-,15-/m0/s1	AMXWFUMPTGFRGD-FGRDXJNISA-N	50473534	CHEMBL354611	Alpha-2A adrenergic receptor		 3.2								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473534&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			135433755	433940799							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155414	CN[C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]5NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C(O)=O)c3O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1)c(Cl)c2	InChI=1S/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95)/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-/m0/s1	MYPYJXKWCTUITO-LYRMYLQWSA-N	50335519	(S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-((S)-6-hydroxy-2-imino-hexahydro-pyrimidin-4-yl)-9,12-bis-hydroxymethyl-2,5,8,11,14-pentaoxo-6-[1-ureido-meth-(Z)-ylidene]-1,4,7,10,13pentaaza-cyclohexadec-15-yl}-amide::4-Naphthalen-2-ylmethyl-4,5-dihydro-1H-imidazole::CHEMBL262777::Chloroorienticin B derivative::Glycopeptide antibiotic::Mannopeptimycin Glycopeptide::Mannopeptimycin glycopeptide analogue::N-demethylvancomycin derivative::Poly ethylene glycol derivative::Tuberactinomycin Analogue::Vancocin::Vancoled::Vancor::Viomycin derivative::vancomycin::vanomycin	Alpha-2A adrenergic receptor		 50								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335519&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14969	125085621	28001	CHEMBL262777	DB00512				1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155464	C(C1CN=CN1)C1=Cc2ccccc2CC1	InChI=1S/C14H16N2/c1-2-4-13-7-11(5-6-12(13)3-1)8-14-9-15-10-16-14/h1-4,7,10,14H,5-6,8-9H2,(H,15,16)	WNPGIHKSPQIODH-UHFFFAOYSA-N	50473559	CHEMBL407509	Alpha-2A adrenergic receptor		 100								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473559&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10176715	433940824							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151059	CC1=C(C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C36H39N3O5/c1-24-31(33(32(35(41)42)25(2)38-24)26-14-15-29-30(22-26)44-23-43-29)34(40)37-18-9-19-39-20-16-36(17-21-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-15,22,33,38H,9,16-21,23H2,1-2H3,(H,37,40)(H,41,42)	GUTLHNWEBBMLCC-UHFFFAOYSA-N	50471688	CHEMBL313251	Alpha-2A adrenergic receptor		 1175								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471688&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10579368	433938953							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151077	CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C35H39N5O4/c1-24-30(33(36)41)32(26-14-16-29(17-15-26)40(43)44)31(25(2)38-24)34(42)37-20-9-21-39-22-18-35(19-23-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17,30,32H,9,18-23H2,1-2H3,(H2,36,41)(H,37,42)	JWIXQLYEPDLLJM-UHFFFAOYSA-N	50068828	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL279436	Alpha-2A adrenergic receptor		 301								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068828&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53978088	103963006		CHEMBL279436				ZINC28759508	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151083	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(OC)cc1	InChI=1S/C37H43N3O4/c1-26-32(34(28-16-18-31(43-3)19-17-28)33(27(2)39-26)36(42)44-4)35(41)38-22-11-23-40-24-20-37(21-25-40,29-12-7-5-8-13-29)30-14-9-6-10-15-30/h5-10,12-19,34,42H,11,20-25H2,1-4H3,(H,38,41)/b36-33+	VHYJQKUBUIGDCY-PKUSAGTQSA-N	50471701	CHEMBL315538	Alpha-2A adrenergic receptor		 2188								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471701&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10841190	433938966							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51151091	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(Cl)c(Cl)c1	InChI=1S/C36H39Cl2N3O3/c1-24-31(33(26-15-16-29(37)30(38)23-26)32(25(2)40-24)35(43)44-3)34(42)39-19-10-20-41-21-17-36(18-22-41,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23,33,43H,10,17-22H2,1-3H3,(H,39,42)/b35-32+	JZHXLYHEWUWHQL-LVYIWIAJSA-N	50471687	CHEMBL327712	Alpha-2A adrenergic receptor		 912								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471687&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10651654	433938952							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155481	Fc1cccc2CCC(CC3CN=CN3)=Cc12	InChI=1S/C14H15FN2/c15-14-3-1-2-11-5-4-10(7-13(11)14)6-12-8-16-9-17-12/h1-3,7,9,12H,4-6,8H2,(H,16,17)	WPIIASRYSZGPAA-UHFFFAOYSA-N	50473561	CHEMBL353139	Alpha-2A adrenergic receptor		 40								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473561&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12981867	433940826							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155515	C(C1CN=CN1)c1cc2ccccc2o1	InChI=1S/C12H12N2O/c1-2-4-12-9(3-1)5-11(15-12)6-10-7-13-8-14-10/h1-5,8,10H,6-7H2,(H,13,14)	XYKLDBVIJCCWKG-UHFFFAOYSA-N	50473525	CHEMBL167644	Alpha-2A adrenergic receptor		 20								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473525&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12981870	433940790							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155547	C1N=CN[C@@]11CC[C@@H]2Cc3ccccc3C[C@H]2C1	InChI=1S/C16H20N2/c1-2-4-13-8-15-9-16(10-17-11-18-16)6-5-14(15)7-12(13)3-1/h1-4,11,14-15H,5-10H2,(H,17,18)/t14-,15+,16-/m1/s1	BAMMEMQIAYAJNE-OWCLPIDISA-N	50473529	CHEMBL165529	Alpha-2A adrenergic receptor		 1.3								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473529&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10847653	433940794							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155549	Clc1cccc2CCC(CC3CN=CN3)=Cc12	InChI=1S/C14H15ClN2/c15-14-3-1-2-11-5-4-10(7-13(11)14)6-12-8-16-9-17-12/h1-3,7,9,12H,4-6,8H2,(H,16,17)	MBYRWLFNVFMLCK-UHFFFAOYSA-N	50473553	CHEMBL353200	Alpha-2A adrenergic receptor		 32								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473553&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			15463615	433940818							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155560	C([C@H]1CN=CN1)[C@@]12CC1c1ccccc1CC2	InChI=1S/C15H18N2/c1-2-4-13-11(3-1)5-6-15(8-14(13)15)7-12-9-16-10-17-12/h1-4,10,12,14H,5-9H2,(H,16,17)/t12-,14?,15-/m0/s1	UBVJBBCZXIOSMF-JDLVMGNASA-N	50473540	CHEMBL353212	Alpha-2A adrenergic receptor		 63								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473540&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			136078488	433940805							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155561	C(C1Cc2ccccc2C1)C1CN=CN1	InChI=1S/C13H16N2/c1-2-4-12-6-10(5-11(12)3-1)7-13-8-14-9-15-13/h1-4,9-10,13H,5-8H2,(H,14,15)	OOIBKWSVXJWTHR-UHFFFAOYSA-N	50473543	CHEMBL353843	Alpha-2A adrenergic receptor		 4.0								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473543&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9990389	433940808							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155569	Fc1ccc2CCC(CC3CN=CN3)=Cc2c1	InChI=1S/C14H15FN2/c15-13-4-3-11-2-1-10(5-12(11)7-13)6-14-8-16-9-17-14/h3-5,7,9,14H,1-2,6,8H2,(H,16,17)	WWUPWXOAAVDTKR-UHFFFAOYSA-N	50473565	CHEMBL436234	Alpha-2A adrenergic receptor		 158								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473565&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12981869	433940830							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155571	CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1	InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3	RTHCYVBBDHJXIQ-UHFFFAOYSA-N	30130	CHEMBL1201082::CHEMBL41::Fluoxetin::Fluoxetine::Prozac::US9120771, Fluoxetine::cid_62857	Alpha-2A adrenergic receptor		 6.3								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30130&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	RFX	4MM8,3GWV	3386	85147891	5118	CHEMBL1201082CHEMBL41	DB00472	203		ZINC01530638	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155582	CCC1(Cc2ccccc2C1)c1cnc[nH]1	InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)	HSWPZIDYAHLZDD-UHFFFAOYSA-N	81807	ATIPAMEZOLE::CAS_104054-27-5::NSC_71310	Alpha-2A adrenergic receptor		 3.2								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81807&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71310	131342381						ZINC05424171	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51155587	Clc1cccc2ccc(CC3CN=CN3)cc12	InChI=1S/C14H13ClN2/c15-14-3-1-2-11-5-4-10(7-13(11)14)6-12-8-16-9-17-12/h1-5,7,9,12H,6,8H2,(H,16,17)	LICJPBUGTHDADI-UHFFFAOYSA-N	50473554	CHEMBL168168	Alpha-2A adrenergic receptor		 25								ChEMBL	10.1021/jm001040g	10.7270/Q2JQ13R9	11262089			Cordi, AA; Berque-Bestel, I; Persigand, T; Lacoste, JM; Newman-Tancredi, A; Audinot, V; Millan, MJ	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473554&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23292293	433940819							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51184826	CCS(=O)(=O)Nc1cccc(Cc2cnc[nH]2)c1	InChI=1S/C12H15N3O2S/c1-2-18(16,17)15-11-5-3-4-10(6-11)7-12-8-13-9-14-12/h3-6,8-9,15H,2,7H2,1H3,(H,13,14)	ROUIPNDCVDWYEH-UHFFFAOYSA-N	50118705	ABT-866::CHEMBL326702::Ethanesulfonic acid [3-(1H-imidazol-4-ylmethyl)-phenyl]-amide::N-(3-((1H-imidazol-4-yl)methyl)phenyl)ethanesulfonamide::N-[3-(1H-imidazol-4-ylmethyl)-phenyl]ethanesulfonamide	Alpha-2A adrenergic receptor		 170								ChEMBL	10.1007/s00044-004-0020-z	10.7270/Q2PZ5CQB				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118705&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9838192	104011969		CHEMBL326702				ZINC00008784	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51184838	CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)C1=NCCN1	InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)	OQFCXJDXHCDLHX-UHFFFAOYSA-N	50118703	CHEMBL109783::N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl]-methanesulfonamide	Alpha-2A adrenergic receptor		 33								ChEMBL	10.1007/s00044-004-0020-z	10.7270/Q2PZ5CQB				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118703&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4038180	104011967		CHEMBL109783		480		ZINC03995494	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51175906	OC(=O)CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1	InChI=1S/C24H33N3O4/c28-21(29)9-2-1-5-12-26-14-10-18(11-15-26)17-25-23(30)22-19-7-3-4-8-20(19)27-13-6-16-31-24(22)27/h3-4,7-8,18H,1-2,5-6,9-17H2,(H,25,30)(H,28,29)	ODMLUIATXKBXOW-UHFFFAOYSA-N	50483176	CHEMBL1632174	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2010.10.011	10.7270/Q2FR00GH	21075638			Brudeli, B; Moltzau, LR; Andressen, KW; Krobert, KA; Klaveness, J; Levy, FO	Drug Discovery Laboratory AS	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50483176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50483176&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50898778	433950441							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51175938	COC(=O)CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1	InChI=1S/C25H35N3O4/c1-31-22(29)10-3-2-6-13-27-15-11-19(12-16-27)18-26-24(30)23-20-8-4-5-9-21(20)28-14-7-17-32-25(23)28/h4-5,8-9,19H,2-3,6-7,10-18H2,1H3,(H,26,30)	RNXYMZNGMNWKMC-UHFFFAOYSA-N	50483172	CHEMBL1632158	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2010.10.011	10.7270/Q2FR00GH	21075638			Brudeli, B; Moltzau, LR; Andressen, KW; Krobert, KA; Klaveness, J; Levy, FO	Drug Discovery Laboratory AS	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50483172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50483172&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50898777	433950437							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199400	C[C@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m0/s1	QYCJTZDZQXSXSC-JTQLQIEISA-N	50417346	CHEMBL1276220	Alpha-2A adrenergic receptor		 21								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836303	163366370		CHEMBL1276220					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199402	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2A adrenergic receptor		 36								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199405	C(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-2-4-13(12(3-1)9-11-5-6-11)17-10-14-15-7-8-16-14/h1-4,11H,5-10H2,(H,15,16)	OTXMFMMMNBKXQC-UHFFFAOYSA-N	50493430	CHEMBL2431281	Alpha-2A adrenergic receptor		 78								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493430&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			72947314	433960695							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199430	C1CN=C(N1)c1cc2ccccc2o1	InChI=1S/C11H10N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-4,7H,5-6H2,(H,12,13)	YTJOHEUHUVBKSB-UHFFFAOYSA-N	50086502	2-BFi::2-Benzofuran-2-yl-4,5-dihydro-1H-imidazole::CHEMBL404505	Alpha-2A adrenergic receptor		 26915								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086502&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3080926	103985710		CHEMBL404505				ZINC02567727	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199435	CCCc1ccccc1OCC1=NCCN1	InChI=1S/C13H18N2O/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h3-4,6-7H,2,5,8-10H2,1H3,(H,14,15)	KJTFLBJQHBFQAF-UHFFFAOYSA-N	50473179	CHEMBL13917	Alpha-2A adrenergic receptor		 49								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473179&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269013	433940444							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199436	C=CCc1ccccc1OCC1=NCCN1	InChI=1S/C13H16N2O/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h2-4,6-7H,1,5,8-10H2,(H,14,15)	YFPXOLILPOTYIP-UHFFFAOYSA-N	50473154	CHEMBL14107	Alpha-2A adrenergic receptor		 126								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473154&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269006	433940419							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199437	C[C@@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m1/s1	QYCJTZDZQXSXSC-SNVBAGLBSA-N	50417345	CHEMBL1276219	Alpha-2A adrenergic receptor		 45								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417345&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836304	163366369		CHEMBL1276219					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199438	C[C@@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m1/s1	SEKAQUSPSDPIAN-LLVKDONJSA-N	50420341	CHEMBL2089155	Alpha-2A adrenergic receptor		 45								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420341&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70693375	163369365		CHEMBL2089155					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199439	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2A adrenergic receptor		 52								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199440	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2A adrenergic receptor		 58								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199460	C[C@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m0/s1	SEKAQUSPSDPIAN-NSHDSACASA-N	50420342	CHEMBL2089156	Alpha-2A adrenergic receptor		 42								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70695474	163369366		CHEMBL2089156					1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199466	C(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C13H16N2O2/c1-2-4-12(17-10-5-6-10)11(3-1)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	JFZSEYPHJYDMAZ-UHFFFAOYSA-N	50493431	CHEMBL2431280	Alpha-2A adrenergic receptor		 316								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493431&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			72947315	433960696							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199470	Brc1ccccc1OCC1=NCCN1	InChI=1S/C10H11BrN2O/c11-8-3-1-2-4-9(8)14-7-10-12-5-6-13-10/h1-4H,5-7H2,(H,12,13)	KSQOPRCDYFOHET-UHFFFAOYSA-N	50493432	CHEMBL2431279	Alpha-2A adrenergic receptor		 95								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493432&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			28918670	433960697							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199471	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2A adrenergic receptor		 100								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199475	C(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	YAORIDZYZDUZCM-UHFFFAOYSA-N	50027060	2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole::2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole (cirazoline)::CHEMBL13852::CIRAZOLINE	Alpha-2A adrenergic receptor		 59								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027060&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2765	103936642		CHEMBL13852	DB09202	515		ZINC00001160	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199489	CC(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C14H18N2O2/c1-10(14-15-8-9-16-14)17-12-4-2-3-5-13(12)18-11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	OHLOMHGVALXPJP-UHFFFAOYSA-N	50419880	CHEMBL1956197	Alpha-2A adrenergic receptor		 83								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419880&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345629	163368904		CHEMBL1956197				ZINC73312422	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199490	CC(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	QYCJTZDZQXSXSC-UHFFFAOYSA-N	50417344	CHEMBL1276218	Alpha-2A adrenergic receptor		 23								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417344&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44549156	163366368		CHEMBL1276218				ZINC64393121	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199501	CCCc1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	NFKNRFTZWQGNTI-UHFFFAOYSA-N	50493433	CHEMBL2431282	Alpha-2A adrenergic receptor		 50								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493433&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			73291731	433960698							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51199505	CC(Oc1ccccc1Br)C1=NCCN1	InChI=1S/C11H13BrN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	NFGYJBCMYUYKCI-UHFFFAOYSA-N	50419874	CHEMBL1956192	Alpha-2A adrenergic receptor		 23								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419874&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345626	163368898		CHEMBL1956192				ZINC73315479	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51210372	C1CNC(N1)=Nn1ncc2ccccc12	InChI=1S/C10H11N5/c1-2-4-9-8(3-1)7-13-15(9)14-10-11-5-6-12-10/h1-4,7H,5-6H2,(H2,11,12,14)	PFTFJTOQCWYCNM-UHFFFAOYSA-N	50271255	1-[(Imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1186220::CHEMBL454712	Alpha-2A adrenergic receptor					 93					ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271255&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24882007	104116144		CHEMBL454712CHEMBL1186220				ZINC40846960	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51210379	Fc1ccc2cnn(N=C3NCCN3)c2c1	InChI=1S/C10H10FN5/c11-8-2-1-7-6-14-16(9(7)5-8)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	IYLGKCYRBQLWIN-UHFFFAOYSA-N	50497435	CHEMBL3343699	Alpha-2A adrenergic receptor					 39					ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50497435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50497435&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118717248	433964700							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51210380	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2A adrenergic receptor					 129					ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51210392	Fc1ccc2cnn(N=C3NCCN3)c2c1	InChI=1S/C10H10FN5/c11-8-2-1-7-6-14-16(9(7)5-8)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	IYLGKCYRBQLWIN-UHFFFAOYSA-N	50497435	CHEMBL3343699	Alpha-2A adrenergic receptor		 33								ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50497435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50497435&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118717248	433964700							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51210402	Fc1cccc2cnn(N=C3NCCN3)c12	InChI=1S/C10H10FN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	NGEQXHFDGLOZSS-UHFFFAOYSA-N	50497439	CHEMBL3343700	Alpha-2A adrenergic receptor		 65								ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50497439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50497439&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118717249	433964704							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51210406	Fc1cccc2cnn(N=C3NCCN3)c12	InChI=1S/C10H10FN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	NGEQXHFDGLOZSS-UHFFFAOYSA-N	50497439	CHEMBL3343700	Alpha-2A adrenergic receptor					 200					ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50497439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50497439&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118717249	433964704							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51210407	C1CNC(N1)=Nn1ncc2ccccc12	InChI=1S/C10H11N5/c1-2-4-9-8(3-1)7-13-15(9)14-10-11-5-6-12-10/h1-4,7H,5-6H2,(H2,11,12,14)	PFTFJTOQCWYCNM-UHFFFAOYSA-N	50271255	1-[(Imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1186220::CHEMBL454712	Alpha-2A adrenergic receptor		 52								ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271255&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24882007	104116144		CHEMBL454712CHEMBL1186220				ZINC40846960	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51214963	CC(C)NCC(O)COc1cccc2ccccc12	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3	AQHHHDLHHXJYJD-UHFFFAOYSA-N	25761	Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine	Alpha-2A adrenergic receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SNP	1DY4,6EKZ,6PS5,5FUK	4946	56413049	8499	CHEMBL27	DB00571	564	C07407	ZINC00056556	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51214988	CB1Nc2c(OCC(O)CN(C)C)cccc2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-11-5-4-6-13(14(11)16-15)19-10-12(18)9-17(2)3/h4-8,12,16,18H,9-10H2,1-3H3	CCSPGLLRANVKRG-UHFFFAOYSA-N	50499310	CHEMBL3736433	Alpha-2A adrenergic receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499310&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034966	433911211							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51215048	CC(C)NCC(O)COc1cccc2ccccc12	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3	AQHHHDLHHXJYJD-UHFFFAOYSA-N	25761	Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine	Alpha-2A adrenergic receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SNP	1DY4,6EKZ,6PS5,5FUK	4946	56413049	8499	CHEMBL27	DB00571	564	C07407	ZINC00056556	1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51215049	CB1Nc2cccc(OCC(O)CN(C)C)c2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-12-13(16-15)5-4-6-14(12)19-10-11(18)9-17(2)3/h4-8,11,16,18H,9-10H2,1-3H3	KVVLFJLSBAOKPZ-UHFFFAOYSA-N	50499311	CHEMBL3736156	Alpha-2A adrenergic receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499311&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034967	433911212							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51215086	CB1Nc2c(OCC(O)CN(C)C)cccc2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-11-5-4-6-13(14(11)16-15)19-10-12(18)9-17(2)3/h4-8,12,16,18H,9-10H2,1-3H3	CCSPGLLRANVKRG-UHFFFAOYSA-N	50499310	CHEMBL3736433	Alpha-2A adrenergic receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499310&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034966	433911211							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51215091	CB1Nc2cccc(OCC(O)CN(C)C)c2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-12-13(16-15)5-4-6-14(12)19-10-11(18)9-17(2)3/h4-8,11,16,18H,9-10H2,1-3H3	KVVLFJLSBAOKPZ-UHFFFAOYSA-N	50499311	CHEMBL3736156	Alpha-2A adrenergic receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499311&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034967	433911212							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259639	c1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccccc1	InChI=1S/C17H12N4/c1-2-4-13(5-3-1)17-19-11-14-10-15(6-7-16(14)20-17)21-9-8-18-12-21/h1-12H	CSZGXYBGYFNSCO-UHFFFAOYSA-N	113058	US8633208, 1	Alpha-2A adrenergic receptor		 2238721								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113058&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24898732	199994774							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259640	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(cc1)-c1ccccc1)c1ccccc1	InChI=1S/C28H27N2O5P/c1-3-34-36(33,35-4-2)28(22-13-9-6-10-14-22)25-24(19-29-28)26(31)30(27(25)32)23-17-15-21(16-18-23)20-11-7-5-8-12-20/h5-19,24-25H,3-4H2,1-2H3	JJVJOMSWQXGHMG-UHFFFAOYSA-N	50514719	CHEMBL4590209	Alpha-2A adrenergic receptor		 7586								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514719&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155567867	440723301							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259641	CCOP(=O)(OCC)C1(Cc2ccccc2)N=CC2C1C(=O)N(C2=O)c1ccccc1	InChI=1S/C23H25N2O5P/c1-3-29-31(28,30-4-2)23(15-17-11-7-5-8-12-17)20-19(16-24-23)21(26)25(22(20)27)18-13-9-6-10-14-18/h5-14,16,19-20H,3-4,15H2,1-2H3	RAACRCLRUKGFAS-UHFFFAOYSA-N	50514720	CHEMBL4469237	Alpha-2A adrenergic receptor		 114815								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514720&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155533747	440723302							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259649	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(Oc2ccccc2)cc1)c1ccccc1	InChI=1S/C28H27N2O6P/c1-3-34-37(33,35-4-2)28(20-11-7-5-8-12-20)25-24(19-29-28)26(31)30(27(25)32)21-15-17-23(18-16-21)36-22-13-9-6-10-14-22/h5-19,24-25H,3-4H2,1-2H3	DNJHTCJTNVXPMX-UHFFFAOYSA-N	50514728	CHEMBL4533687	Alpha-2A adrenergic receptor		 3715								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514728&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155547141	440723310							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259650	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1c(Cl)cc(Cl)cc1Cl)c1ccccc1	InChI=1S/C22H20Cl3N2O5P/c1-3-31-33(30,32-4-2)22(13-8-6-5-7-9-13)18-15(12-26-22)20(28)27(21(18)29)19-16(24)10-14(23)11-17(19)25/h5-12,15,18H,3-4H2,1-2H3	BAHUODHTDBMEAI-UHFFFAOYSA-N	50514729	CHEMBL4459403	Alpha-2A adrenergic receptor		 6918								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514729&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155526672	440723311							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259651	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1cc(Cl)cc(Cl)c1)c1ccccc1	InChI=1S/C22H21Cl2N2O5P/c1-3-30-32(29,31-4-2)22(14-8-6-5-7-9-14)19-18(13-25-22)20(27)26(21(19)28)17-11-15(23)10-16(24)12-17/h5-13,18-19H,3-4H2,1-2H3	NAWURGNNGRBMBX-UHFFFAOYSA-N	50514730	CHEMBL4456882	Alpha-2A adrenergic receptor		 603								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514730	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514730&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155525779	440723312							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259652	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccccc1Cl)c1ccccc1	InChI=1S/C22H22ClN2O5P/c1-3-29-31(28,30-4-2)22(15-10-6-5-7-11-15)19-16(14-24-22)20(26)25(21(19)27)18-13-9-8-12-17(18)23/h5-14,16,19H,3-4H2,1-2H3	QJJYVPRKXWLVCX-UHFFFAOYSA-N	50514731	CHEMBL4528557	Alpha-2A adrenergic receptor		 708								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514731&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155544935	440723313							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259653	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C1Cc3ccccc3C1)C2=O)c1ccccc1	InChI=1S/C25H27N2O5P/c1-3-31-33(30,32-4-2)25(19-12-6-5-7-13-19)22-21(16-26-25)23(28)27(24(22)29)20-14-17-10-8-9-11-18(17)15-20/h5-13,16,20-22H,3-4,14-15H2,1-2H3	ASPYCBWPMRYMRJ-UHFFFAOYSA-N	50514732	CHEMBL4553853	Alpha-2A adrenergic receptor		 363078								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514732&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155555790	440723314							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259654	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(Cc1ccccc1)C2=O)c1ccccc1	InChI=1S/C23H25N2O5P/c1-3-29-31(28,30-4-2)23(18-13-9-6-10-14-18)20-19(15-24-23)21(26)25(22(20)27)16-17-11-7-5-8-12-17/h5-15,19-20H,3-4,16H2,1-2H3	CKDAUWLSGDDWBI-UHFFFAOYSA-N	50514718	CHEMBL4438158	Alpha-2A adrenergic receptor		 7.8								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514718&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155513073	440723300							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259655	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(CC13CC4CC(CC(C4)C1)C3)C2=O)c1ccccc1	InChI=1S/C27H35N2O5P/c1-3-33-35(32,34-4-2)27(21-8-6-5-7-9-21)23-22(16-28-27)24(30)29(25(23)31)17-26-13-18-10-19(14-26)12-20(11-18)15-26/h5-9,16,18-20,22-23H,3-4,10-15,17H2,1-2H3	BZDXHUHJTOQCFC-UHFFFAOYSA-N	50514733	CHEMBL4445396	Alpha-2A adrenergic receptor		 48978								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514733&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155517797	440723315							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259656	CCOP(=O)(OCC)C1(Cc2ccc(F)cc2)N=CC2C1C(=O)N(C2=O)c1ccccc1	InChI=1S/C23H24FN2O5P/c1-3-30-32(29,31-4-2)23(14-16-10-12-17(24)13-11-16)20-19(15-25-23)21(27)26(22(20)28)18-8-6-5-7-9-18/h5-13,15,19-20H,3-4,14H2,1-2H3	MOENSVDMWUJSGJ-UHFFFAOYSA-N	50514734	CHEMBL4568994	Alpha-2A adrenergic receptor		 63								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514734&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155550341	440723316							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259657	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccccc1)c1ccc(OC)cc1	InChI=1S/C23H25N2O6P/c1-4-30-32(28,31-5-2)23(16-11-13-18(29-3)14-12-16)20-19(15-24-23)21(26)25(22(20)27)17-9-7-6-8-10-17/h6-15,19-20H,4-5H2,1-3H3	SDPPTODDMGKLES-UHFFFAOYSA-N	50514735	CHEMBL4584406	Alpha-2A adrenergic receptor		 141254								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514735&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155566387	440723317							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259658	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(F)c(Cl)c1)c1ccc(F)cc1	InChI=1S/C22H20ClF2N2O5P/c1-3-31-33(30,32-4-2)22(13-5-7-14(24)8-6-13)19-16(12-26-22)20(28)27(21(19)29)15-9-10-18(25)17(23)11-15/h5-12,16,19H,3-4H2,1-2H3	HOCDYFTYPBFXML-UHFFFAOYSA-N	50514736	CHEMBL4465834	Alpha-2A adrenergic receptor		 416869								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514736&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155531234	440723318							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259659	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(F)c(Cl)c1)c1ccccc1	InChI=1S/C22H21ClFN2O5P/c1-3-30-32(29,31-4-2)22(14-8-6-5-7-9-14)19-16(13-25-22)20(27)26(21(19)28)15-10-11-18(24)17(23)12-15/h5-13,16,19H,3-4H2,1-2H3	AOHIJBRGGKXQOP-UHFFFAOYSA-N	50514721	CHEMBL4450506	Alpha-2A adrenergic receptor		 537								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514721&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155521287	440723303							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259660	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccccc1)c1ccccc1	InChI=1S/C22H23N2O5P/c1-3-28-30(27,29-4-2)22(16-11-7-5-8-12-16)19-18(15-23-22)20(25)24(21(19)26)17-13-9-6-10-14-17/h5-15,18-19H,3-4H2,1-2H3	ZSWAWPHPIFZGTL-UHFFFAOYSA-N	50514737	CHEMBL4482861	Alpha-2A adrenergic receptor		 0.041687								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514737&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155540329	440723319							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259661	CCOP(=O)(OCC)C1N=CC2C1C(=O)N(C2=O)c1ccc(OC)cc1	InChI=1S/C17H21N2O6P/c1-4-24-26(22,25-5-2)15-14-13(10-18-15)16(20)19(17(14)21)11-6-8-12(23-3)9-7-11/h6-10,13-15H,4-5H2,1-3H3	RCUIZXHMVBJQPJ-UHFFFAOYSA-N	50514738	CHEMBL4536304	Alpha-2A adrenergic receptor		 0.053703								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514738&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			78114674	440723320							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259662	CCOP(=O)(OCC)C1N=CC2C1C(=O)N(C)C2=O	InChI=1S/C11H17N2O5P/c1-4-17-19(16,18-5-2)9-8-7(6-12-9)10(14)13(3)11(8)15/h6-9H,4-5H2,1-3H3	OIGXZBISTBFTDV-UHFFFAOYSA-N	50514739	CHEMBL4467833	Alpha-2A adrenergic receptor		 4.5								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514739&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			78114881	440723321							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259663	C1CN=C(N1)c1cc2ccccc2o1	InChI=1S/C11H10N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-4,7H,5-6H2,(H,12,13)	YTJOHEUHUVBKSB-UHFFFAOYSA-N	50086502	2-BFi::2-Benzofuran-2-yl-4,5-dihydro-1H-imidazole::CHEMBL404505	Alpha-2A adrenergic receptor		 229								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086502&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3080926	103985710		CHEMBL404505				ZINC02567727	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259664	Cn1c(cc2ccccc12)C1=NCCN1	InChI=1S/C12H13N3/c1-15-10-5-3-2-4-9(10)8-11(15)12-13-6-7-14-12/h2-5,8H,6-7H2,1H3,(H,13,14)	LOFCLFKSYRAAFZ-UHFFFAOYSA-N	50226966	CHEMBL41103	Alpha-2A adrenergic receptor		 42658								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226966&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13869716	378167166		CHEMBL41103					1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259665	CCOP(=O)(OCC)C1N=CC2C1C(=O)N(C1CCCCC1)C2=O	InChI=1S/C16H25N2O5P/c1-3-22-24(21,23-4-2)14-13-12(10-17-14)15(19)18(16(13)20)11-8-6-5-7-9-11/h10-14H,3-9H2,1-2H3	CIWHQJBTCNPDOW-UHFFFAOYSA-N	50514727	CHEMBL4483022	Alpha-2A adrenergic receptor		 0.323594								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514727&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			78114597	440723309							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259671	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1cccc2ccccc12)c1ccccc1	InChI=1S/C26H25N2O5P/c1-3-32-34(31,33-4-2)26(19-13-6-5-7-14-19)23-21(17-27-26)24(29)28(25(23)30)22-16-10-12-18-11-8-9-15-20(18)22/h5-17,21,23H,3-4H2,1-2H3	JOYXNXRIHORZKV-UHFFFAOYSA-N	50514740	CHEMBL4531381	Alpha-2A adrenergic receptor		<1000000								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514740&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155546560	440723322							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259672	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(cc1)C(F)(F)F)c1ccccc1	InChI=1S/C23H22F3N2O5P/c1-3-32-34(31,33-4-2)22(15-8-6-5-7-9-15)19-18(14-27-22)20(29)28(21(19)30)17-12-10-16(11-13-17)23(24,25)26/h5-14,18-19H,3-4H2,1-2H3	YHEYAZQEOLSQKE-UHFFFAOYSA-N	50514741	CHEMBL4476557	Alpha-2A adrenergic receptor		 18621								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514741	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514741&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155538461	440723323							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259673	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(CC)C2=O)c1ccccc1	InChI=1S/C18H23N2O5P/c1-4-20-16(21)14-12-19-18(15(14)17(20)22,13-10-8-7-9-11-13)26(23,24-5-2)25-6-3/h7-12,14-15H,4-6H2,1-3H3	JJIRPDIZJVWLJK-UHFFFAOYSA-N	50514742	CHEMBL4587519	Alpha-2A adrenergic receptor		 1413								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514742&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155566429	440723324							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259674	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccccc1)c1ccc(F)cc1	InChI=1S/C22H22FN2O5P/c1-3-29-31(28,30-4-2)22(15-10-12-16(23)13-11-15)19-18(14-24-22)20(26)25(21(19)27)17-8-6-5-7-9-17/h5-14,18-19H,3-4H2,1-2H3	NRTOQQUFECNALA-UHFFFAOYSA-N	50514743	CHEMBL4454147	Alpha-2A adrenergic receptor		 170								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514743	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514743&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155523897	440723325							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259675	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C)C2=O)c1ccccc1	InChI=1S/C17H21N2O5P/c1-4-23-25(22,24-5-2)17(12-9-7-6-8-10-12)14-13(11-18-17)15(20)19(3)16(14)21/h6-11,13-14H,4-5H2,1-3H3	KOZKGCYTRIIXBI-UHFFFAOYSA-N	50514725	CHEMBL4459090	Alpha-2A adrenergic receptor		 1175								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514725&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155526524	440723307							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259680	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(CCc1ccc(F)cc1)C2=O)c1ccccc1	InChI=1S/C24H26FN2O5P/c1-3-31-33(30,32-4-2)24(18-8-6-5-7-9-18)21-20(16-26-24)22(28)27(23(21)29)15-14-17-10-12-19(25)13-11-17/h5-13,16,20-21H,3-4,14-15H2,1-2H3	ZERIGJALQBIPQT-UHFFFAOYSA-N	50514746	CHEMBL4587003	Alpha-2A adrenergic receptor		 2239								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514746	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514746&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155566702	440723328							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259681	CCOP(=O)(OCC)C1N=CC2C1C(=O)N(C2=O)c1ccc(F)c(Cl)c1	InChI=1S/C16H17ClFN2O5P/c1-3-24-26(23,25-4-2)14-13-10(8-19-14)15(21)20(16(13)22)9-5-6-12(18)11(17)7-9/h5-8,10,13-14H,3-4H2,1-2H3	GDBRUKFBBFJPAM-UHFFFAOYSA-N	50514745	CHEMBL4439953	Alpha-2A adrenergic receptor		 3.2								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514745&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			78114676	440723327							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259682	c1c[nH]c(n1)-c1cc2ccccc2o1	InChI=1S/C11H8N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-7H,(H,12,13)	VBFQIUOSXHUWCT-UHFFFAOYSA-N	50514747	CHEMBL151697	Alpha-2A adrenergic receptor		 6761								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514747&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XCG	2XFN,2XFO,2XFP,2XFQ,2XCG	3073596	440723329							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259683	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(F)c(Cl)c1)c1ccccc1	InChI=1S/C22H21ClFN2O5P/c1-3-30-32(29,31-4-2)22(14-8-6-5-7-9-14)19-16(13-25-22)20(27)26(21(19)28)15-10-11-18(24)17(23)12-15/h5-13,16,19H,3-4H2,1-2H3	AOHIJBRGGKXQOP-UHFFFAOYSA-N	50514721	CHEMBL4450506	Alpha-2A adrenergic receptor		 537								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514721&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155521287	440723303							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259684	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1cccnc1Cl)c1ccccc1	InChI=1S/C21H21ClN3O5P/c1-3-29-31(28,30-4-2)21(14-9-6-5-7-10-14)17-15(13-24-21)19(26)25(20(17)27)16-11-8-12-23-18(16)22/h5-13,15,17H,3-4H2,1-2H3	WARCPVIUSSVEBC-UHFFFAOYSA-N	50514748	CHEMBL4527478	Alpha-2A adrenergic receptor		<1000000								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514748	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514748&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155545196	440723330							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259685	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(F)c(Cl)c1)c1ccc(OC)cc1	InChI=1S/C23H23ClFN2O6P/c1-4-32-34(30,33-5-2)23(14-6-9-16(31-3)10-7-14)20-17(13-26-23)21(28)27(22(20)29)15-8-11-19(25)18(24)12-15/h6-13,17,20H,4-5H2,1-3H3	XDWWNCVFGFGGFX-UHFFFAOYSA-N	50514749	CHEMBL4543019	Alpha-2A adrenergic receptor		<1000000								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514749	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514749&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155551657	440723331							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259686	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1cccc(c1)[N+]([O-])=O)c1ccccc1	InChI=1S/C22H22N3O7P/c1-3-31-33(30,32-4-2)22(15-9-6-5-7-10-15)19-18(14-23-22)20(26)24(21(19)27)16-11-8-12-17(13-16)25(28)29/h5-14,18-19H,3-4H2,1-2H3	CONRLYITUPHTMN-UHFFFAOYSA-N	50514722	CHEMBL4438801	Alpha-2A adrenergic receptor		 0.066069								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514722&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155513359	440723304							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259687	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(F)cc1)c1ccccc1	InChI=1S/C22H22FN2O5P/c1-3-29-31(28,30-4-2)22(15-8-6-5-7-9-15)19-18(14-24-22)20(26)25(21(19)27)17-12-10-16(23)11-13-17/h5-14,18-19H,3-4H2,1-2H3	WCOULMXGZBFAGC-UHFFFAOYSA-N	50514750	CHEMBL4475933	Alpha-2A adrenergic receptor		 4571								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514750&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155538007	440723332							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259688	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(CCc1ccccc1)C2=O)c1ccccc1	InChI=1S/C24H27N2O5P/c1-3-30-32(29,31-4-2)24(19-13-9-6-10-14-19)21-20(17-25-24)22(27)26(23(21)28)16-15-18-11-7-5-8-12-18/h5-14,17,20-21H,3-4,15-16H2,1-2H3	FFGDTBMYCNEKMA-UHFFFAOYSA-N	50514744	CHEMBL4434967	Alpha-2A adrenergic receptor		 169824								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514744	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514744&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155510985	440723326							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259689	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)C(C)(C)C)c1ccccc1	InChI=1S/C20H27N2O5P/c1-6-26-28(25,27-7-2)20(14-11-9-8-10-12-14)16-15(13-21-20)17(23)22(18(16)24)19(3,4)5/h8-13,15-16H,6-7H2,1-5H3	HVCLJLFYVDNOAP-UHFFFAOYSA-N	50514751	CHEMBL4554450	Alpha-2A adrenergic receptor		 170								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514751&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155556443	440723333							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259690	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C2=O)c1ccc(OC)cc1)c1ccccc1	InChI=1S/C23H25N2O6P/c1-4-30-32(28,31-5-2)23(16-9-7-6-8-10-16)20-19(15-24-23)21(26)25(22(20)27)17-11-13-18(29-3)14-12-17/h6-15,19-20H,4-5H2,1-3H3	GZQYNRDGSMATOB-UHFFFAOYSA-N	50514723	CHEMBL4534152	Alpha-2A adrenergic receptor		 25704								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514723&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155546767	440723305							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259691	CCOP(=O)(OCC)C1(N=CC2C1C(=O)N(C1CCCCC1)C2=O)c1ccccc1	InChI=1S/C22H29N2O5P/c1-3-28-30(27,29-4-2)22(16-11-7-5-8-12-16)19-18(15-23-22)20(25)24(21(19)26)17-13-9-6-10-14-17/h5,7-8,11-12,15,17-19H,3-4,6,9-10,13-14H2,1-2H3	DMVFXOFRGGGXKJ-UHFFFAOYSA-N	50514724	CHEMBL4535472	Alpha-2A adrenergic receptor		 0.977237								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514724&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155547631	440723306							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259692	CCOP(=O)(OCC)C1N=CC2C1C(=O)N(C2=O)c1ccccc1	InChI=1S/C16H19N2O5P/c1-3-22-24(21,23-4-2)14-13-12(10-17-14)15(19)18(16(13)20)11-8-6-5-7-9-11/h5-10,12-14H,3-4H2,1-2H3	BXJNWHVUCMPYQT-UHFFFAOYSA-N	50514726	CHEMBL4546903	Alpha-2A adrenergic receptor		 9550								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514726&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			78114671	440723308							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51259693	C1CN=C(N1)\C=C\c1ccccc1	InChI=1S/C11H12N2/c1-2-4-10(5-3-1)6-7-11-12-8-9-13-11/h1-7H,8-9H2,(H,12,13)/b7-6+	IGISUADTPSLENQ-VOTSOKGWSA-N	50138500	2-((E)-Styryl)-4,5-dihydro-1H-imidazole::2-styryl-4,5-dihydro-1H-imidazole::CHEMBL275970	Alpha-2A adrenergic receptor		 46774								ChEMBL	10.1021/acs.jmedchem.9b02080	10.7270/Q2FB569H	32150414			Abás, S; Rodríguez-Arévalo, S; Bagán, A; Griñán-Ferré, C; Vasilopoulou, F; Brocos-Mosquera, I; Muguruza, C; Pérez, B; Molins, E; Luque, FJ; Pérez-Lozano, P; de Jonghe, S; Daelemans, D; Naesens, L; Brea, J; Loza, MI; Hernández-Hernández, E; García-Sevilla, JA; García-Fuster, MJ; Radan, M; Djikic, T; Nikolic, K; Pallàs, M; Callado, LF; Escolano, C	University of Barcelona	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138500&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6455104	104028536		CHEMBL275970				ZINC13520012	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51263831	FC(F)Oc1ccc(NC(=O)NC2CCN(CC2)c2ncnc3n(c(nc23)-c2ccccc2Cl)-c2ccc(Cl)cc2)cn1	InChI=1S/C29H24Cl2F2N8O2/c30-17-5-8-20(9-6-17)41-25(21-3-1-2-4-22(21)31)39-24-26(35-16-36-27(24)41)40-13-11-18(12-14-40)37-29(42)38-19-7-10-23(34-15-19)43-28(32)33/h1-10,15-16,18,28H,11-14H2,(H2,37,38,42)	LTNOPYMLPTUXSM-UHFFFAOYSA-N	50516235	CHEMBL4563408	Alpha-2A adrenergic receptor			>10000							ChEMBL	10.1021/acs.jmedchem.9b00727	10.7270/Q24F1V3D	31185168			Amato, G; Manke, A; Wiethe, R; Vasukuttan, V; Snyder, R; Yueh, YL; Decker, A; Runyon, S; Maitra, R	RTI International	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516235&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			135156251	440724817							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51263832	FC(F)Oc1ccc(NC(=O)NC2CCN(CC2)c2ncnc3n(c(nc23)-c2ccccc2Cl)-c2ccc(Cl)cc2)cn1	InChI=1S/C29H24Cl2F2N8O2/c30-17-5-8-20(9-6-17)41-25(21-3-1-2-4-22(21)31)39-24-26(35-16-36-27(24)41)40-13-11-18(12-14-40)37-29(42)38-19-7-10-23(34-15-19)43-28(32)33/h1-10,15-16,18,28H,11-14H2,(H2,37,38,42)	LTNOPYMLPTUXSM-UHFFFAOYSA-N	50516235	CHEMBL4563408	Alpha-2A adrenergic receptor					>10000					ChEMBL	10.1021/acs.jmedchem.9b00727	10.7270/Q24F1V3D	31185168			Amato, G; Manke, A; Wiethe, R; Vasukuttan, V; Snyder, R; Yueh, YL; Decker, A; Runyon, S; Maitra, R	RTI International	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516235&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			135156251	440724817							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51235315	COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccccc2)CC1	InChI=1S/C28H34FN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(25-8-3-2-4-9-25)22-23-12-14-24(29)15-13-23/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	UDYXSPVICNNUPJ-UHFFFAOYSA-N	50505701	CHEMBL4544086	Alpha-2A adrenergic receptor		 860								ChEMBL	10.1021/acs.jmedchem.9b01085	10.7270/Q2GB27BJ	31613617			Pirzer, AS; Lasch, R; Friedrich, H; Hübner, H; Gmeiner, P; Heinrich, MR	Friedrich-Alexander-Universit&#163;t Erlangen-N&#163;rnberg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50505701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50505701&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155552185	440714286							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51235339	COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1	InChI=1S/C28H35N5O2/c1-35-27-16-9-8-15-26(27)32-21-19-31(20-22-32)18-10-17-29-28(34)30-33(25-13-6-3-7-14-25)23-24-11-4-2-5-12-24/h2-9,11-16H,10,17-23H2,1H3,(H2,29,30,34)	QAESTHCUZJPQGF-UHFFFAOYSA-N	50505700	CHEMBL4442460	Alpha-2A adrenergic receptor		 400								ChEMBL	10.1021/acs.jmedchem.9b01085	10.7270/Q2GB27BJ	31613617			Pirzer, AS; Lasch, R; Friedrich, H; Hübner, H; Gmeiner, P; Heinrich, MR	Friedrich-Alexander-Universit&#163;t Erlangen-N&#163;rnberg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50505700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50505700&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155515982	440714285							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51266545	O[C@@H]1[C@H](O)[C@]2(CCl)C[C@@H]2[C@H]1n1cnc2c(NC(C3CCC3)C3CCC3)ncnc12	InChI=1S/C21H28ClN5O2/c22-8-21-7-13(21)16(17(28)18(21)29)27-10-25-15-19(23-9-24-20(15)27)26-14(11-3-1-4-11)12-5-2-6-12/h9-14,16-18,28-29H,1-8H2,(H,23,24,26)/t13-,16-,17+,18+,21+/m1/s1	KVDBXTJKVCKWRR-UZXPACTOSA-N	50517290	CHEMBL4554295	Alpha-2A adrenergic receptor		 6800								ChEMBL	10.1021/acs.jmedchem.8b01662	10.7270/Q2TM7FGK	30605331			Tosh, DK; Rao, H; Bitant, A; Salmaso, V; Mannes, P; Lieberman, DI; Vaughan, KL; Mattison, JA; Rothwell, AC; Auchampach, JA; Ciancetta, A; Liu, N; Cui, Z; Gao, ZG; Reitman, ML; Gavrilova, O; Jacobson, KA	Medical College of Wisconsin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50517290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50517290&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155556618	440725872							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51224199	CC[C@H]1c2cc(OC)ccc2CC[C@@]1(C)N	InChI=1S/C14H21NO/c1-4-13-12-9-11(16-3)6-5-10(12)7-8-14(13,2)15/h5-6,9,13H,4,7-8,15H2,1-3H3/t13-,14+/m0/s1	OTQHFPJXKACHHP-UONOGXRCSA-N	50503047	CHEMBL4472703	Alpha-2A adrenergic receptor		 6310								ChEMBL	10.1021/acsmedchemlett.9b00225	10.7270/Q2DF6VGQ	31620230			Porter, MR; Xiao, H; Wang, J; Smith, SB; Topczewski, JJ	University of Minnesota Twin Cities	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503047&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155536080	440711632							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51266687	O[C@@H]1[C@@H]2C[C@@H]2[C@H]([C@@H]1O)n1cnc2c(NC(C3CCC3)C3CCC3)nc(Cl)nc12	InChI=1S/C20H26ClN5O2/c21-20-24-18(23-13(9-3-1-4-9)10-5-2-6-10)14-19(25-20)26(8-22-14)15-11-7-12(11)16(27)17(15)28/h8-13,15-17,27-28H,1-7H2,(H,23,24,25)/t11-,12+,15+,16+,17-/m0/s1	BJGMUJOSNVRDQV-GHVWTTSJSA-N	50517288	CHEMBL4471712	Alpha-2A adrenergic receptor		 6960								ChEMBL	10.1021/acs.jmedchem.8b01662	10.7270/Q2TM7FGK	30605331			Tosh, DK; Rao, H; Bitant, A; Salmaso, V; Mannes, P; Lieberman, DI; Vaughan, KL; Mattison, JA; Rothwell, AC; Auchampach, JA; Ciancetta, A; Liu, N; Cui, Z; Gao, ZG; Reitman, ML; Gavrilova, O; Jacobson, KA	Medical College of Wisconsin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50517288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50517288&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155535203	440725870							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51224214	CC[C@H]1c2cc(C)ccc2OC[C@@]1(C)N	InChI=1S/C13H19NO/c1-4-11-10-7-9(2)5-6-12(10)15-8-13(11,3)14/h5-7,11H,4,8,14H2,1-3H3/t11-,13+/m0/s1	DUGAXFUVLZBESY-WCQYABFASA-N	50503043	CHEMBL4528651	Alpha-2A adrenergic receptor		<10000								ChEMBL	10.1021/acsmedchemlett.9b00225	10.7270/Q2DF6VGQ	31620230			Porter, MR; Xiao, H; Wang, J; Smith, SB; Topczewski, JJ	University of Minnesota Twin Cities	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503043&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			153287572	440711628							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51273909	CC[C@@H]1CN2CCc3c([nH]c4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC	InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1	LELBFTMXCIIKKX-QVRQZEMUSA-N	50474152	CHEBI:6956::CHEMBL299031	Alpha-2A adrenergic receptor		 4720								ChEMBL	10.1021/acs.jmedchem.9b01465	10.7270/Q2P55RW6	31834797			Obeng, S; Kamble, SH; Reeves, ME; Restrepo, LF; Patel, A; Behnke, M; Chear, NJ; Ramanathan, S; Sharma, A; León, F; Hiranita, T; Avery, BA; McMahon, LR; McCurdy, CR	University of Florida	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474152&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3034396	433941417					C09226		1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51273920	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2A adrenergic receptor		 3.1								ChEMBL	10.1021/acs.jmedchem.9b01465	10.7270/Q2P55RW6	31834797			Obeng, S; Kamble, SH; Reeves, ME; Restrepo, LF; Patel, A; Behnke, M; Chear, NJ; Ramanathan, S; Sharma, A; León, F; Hiranita, T; Avery, BA; McMahon, LR; McCurdy, CR	University of Florida	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51221312	CCCN1CCC=C(C1)c1cc(no1)-c1ccc(C)cc1	InChI=1S/C18H22N2O/c1-3-10-20-11-4-5-16(13-20)18-12-17(19-21-18)15-8-6-14(2)7-9-15/h5-9,12H,3-4,10-11,13H2,1-2H3	FOQRKFCLRMMKAT-UHFFFAOYSA-N	50251208	CHEMBL4088272	Alpha-2A adrenergic receptor		 8318								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251208&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	61W	5HK1	9817231	401962647							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51221322	CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12	InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)	WHTVZRBIWZFKQO-UHFFFAOYSA-N	22985	Aralen::CHEMBL76::CHLOROQUINE PHOSPHATE::Chlorochin::Chloroquine::Chloroquine, 17::med.21724, Compound 8::{4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine	Alpha-2A adrenergic receptor		 4365								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22985&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	0TX	7ER3,4FGK	2719	49846799	3638	CHEMBL76	DB00608	5535	C07625	ZINC01530861	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51221324	CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1	InChI=1S/C21H26ClNO/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3/t20-,21-/m1/s1	YNNUSGIPVFPVBX-NHCUHLMSSA-N	50253157	(+)-(2R)-2-(2-(((R)-p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine::(+)-(2R)-2-[2-[[(R)-p-chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine::(2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine::CHEMBL1626::CLEMASTINE	Alpha-2A adrenergic receptor		 170								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253157	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253157&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			26987	104105756	3738	CHEMBL1626	DB00283	6063	C06913	ZINC00402830	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51221334	COc1cccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc12	InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3	PHRCDWVPTULQMT-UHFFFAOYSA-N	50048866	1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperazine::1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)propyl]piperazine::1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine::CHEMBL53325::PB-28	Alpha-2A adrenergic receptor		 1514								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048866&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	YT1	7M93	10474335	103979247		CHEMBL53325		6681		ZINC22931097	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51221338	CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12	InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)	XXSMGPRMXLTPCZ-UHFFFAOYSA-N	50467780	CHEBI:5801::Hydroxychloroquine::acs.jmedchem.1c00409_ST.817::med.21724, Compound 9	Alpha-2A adrenergic receptor		 6457								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467780&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3652	433935045					C07043		1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51224429	CC[C@H]1c2ccccc2N(C[C@@]1(C)N)c1ccccc1	InChI=1S/C18H22N2/c1-3-16-15-11-7-8-12-17(15)20(13-18(16,2)19)14-9-5-4-6-10-14/h4-12,16H,3,13,19H2,1-2H3/t16-,18+/m0/s1	WJDLKMWEXVEBMK-FUHWJXTLSA-N	50503044	CHEMBL4572167	Alpha-2A adrenergic receptor		 398								ChEMBL	10.1021/acsmedchemlett.9b00225	10.7270/Q2DF6VGQ	31620230			Porter, MR; Xiao, H; Wang, J; Smith, SB; Topczewski, JJ	University of Minnesota Twin Cities	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503044	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503044&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			153287574	440711629							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51309981	CN1CCC2(CC1)N=C(C)C(=O)N(C2=O)c1c(C)cccc1C	InChI=1S/C18H23N3O2/c1-12-6-5-7-13(2)15(12)21-16(22)14(3)19-18(17(21)23)8-10-20(4)11-9-18/h5-7H,8-11H2,1-4H3	UOZGZTQNYJCRFH-UHFFFAOYSA-N	50531606	CHEMBL4514672	Alpha-2A adrenergic receptor		 3364								ChEMBL	10.1016/j.ejmech.2018.12.048	10.7270/Q2C250XQ	30597325			Uprety, R; Váradi, A; Allaoa, A; Redel-Traub, GN; Palmer, TC; Feinberg, EN; Ferris, AC; Pande, VS; Pasternak, GW; Majumdar, S	Memorial Sloan Kettering Cancer Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50531606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50531606&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155539605	440740188							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51314480	OC(=O)c1cc(cc(c1)-n1cc(nn1)-c1ccc(Cl)s1)-c1ccc(cc1)C1CCNCC1	InChI=1S/C24H21ClN4O2S/c25-23-6-5-22(32-23)21-14-29(28-27-21)20-12-18(11-19(13-20)24(30)31)16-3-1-15(2-4-16)17-7-9-26-10-8-17/h1-6,11-14,17,26H,7-10H2,(H,30,31)	ULWSPLJNOBISBK-UHFFFAOYSA-N	50532693	CHEMBL4544251	Alpha-2A adrenergic receptor		 1560								ChEMBL	10.1021/acs.jmedchem.6b00044	10.7270/Q2DJ5K34	27331270			Junker, A; Balasubramanian, R; Ciancetta, A; Uliassi, E; Kiselev, E; Martiriggiano, C; Trujillo, K; Mtchedlidze, G; Birdwell, L; Brown, KA; Harden, TK; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532693&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			135356876	440741275							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51314488	OC(=O)c1cc(cc(c1)-n1cc(nn1)-c1ccc(Cl)s1)-c1ccc(cc1)C1CCNCC1	InChI=1S/C24H21ClN4O2S/c25-23-6-5-22(32-23)21-14-29(28-27-21)20-12-18(11-19(13-20)24(30)31)16-3-1-15(2-4-16)17-7-9-26-10-8-17/h1-6,11-14,17,26H,7-10H2,(H,30,31)	ULWSPLJNOBISBK-UHFFFAOYSA-N	50532693	CHEMBL4544251	Alpha-2A adrenergic receptor		 1560								ChEMBL	10.1021/acs.jmedchem.6b00044	10.7270/Q2DJ5K34	27331270			Junker, A; Balasubramanian, R; Ciancetta, A; Uliassi, E; Kiselev, E; Martiriggiano, C; Trujillo, K; Mtchedlidze, G; Birdwell, L; Brown, KA; Harden, TK; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532693&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			135356876	440741275							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51287553	COc1ccccc1N1CCN(CCCSc2nnc(-c3ccccc3)n2C)CC1	InChI=1S/C23H29N5OS/c1-26-22(19-9-4-3-5-10-19)24-25-23(26)30-18-8-13-27-14-16-28(17-15-27)20-11-6-7-12-21(20)29-2/h3-7,9-12H,8,13-18H2,1-2H3	RRTCFJGKAMKAIY-UHFFFAOYSA-N	50250803	CHEMBL4083252	Alpha-2A adrenergic receptor		 221								ChEMBL	10.1021/acs.jmedchem.9b00412	10.7270/Q2Z03CM2	31021617			Reilly, SW; Riad, AA; Hsieh, CJ; Sahlholm, K; Jacome, DA; Griffin, S; Taylor, M; Weng, CC; Xu, K; Kirschner, N; Luedtke, RR; Parry, C; Malhotra, S; Karanicolas, J; Mach, RH	University of Pennsylvania	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250803&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137646281	401962417							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51283574	Cc1cc(Oc2nccc3occc23)ccc1-c1c(C)ncc2nccn12	InChI=1S/C21H16N4O2/c1-13-11-15(27-21-17-6-10-26-18(17)5-7-23-21)3-4-16(13)20-14(2)24-12-19-22-8-9-25(19)20/h3-12H,1-2H3	HWAIAGZSWHOLLK-UHFFFAOYSA-N	50465935	CHEMBL4277264	Alpha-2A adrenergic receptor		 3400								ChEMBL	10.1021/acs.jmedchem.9b00351	10.7270/Q2445QWG	30875219			Martini, ML; Liu, J; Ray, C; Yu, X; Huang, XP; Urs, A; Urs, N; McCorvy, JD; Caron, MG; Roth, BL; Jin, J	University of North Carolina at Chapel Hill	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465935	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465935&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			75201901	433933200							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51283575	Cc1ncc2nccn2c1-c1ccc(Oc2nccc3occc23)cc1C(F)(F)F	InChI=1S/C21H13F3N4O2/c1-12-19(28-8-7-25-18(28)11-27-12)14-3-2-13(10-16(14)21(22,23)24)30-20-15-5-9-29-17(15)4-6-26-20/h2-11H,1H3	GEPUWJGKAOGNRH-UHFFFAOYSA-N	50523440	CHEMBL4572614	Alpha-2A adrenergic receptor		 6800								ChEMBL	10.1021/acs.jmedchem.9b00351	10.7270/Q2445QWG	30875219			Martini, ML; Liu, J; Ray, C; Yu, X; Huang, XP; Urs, A; Urs, N; McCorvy, JD; Caron, MG; Roth, BL; Jin, J	University of North Carolina at Chapel Hill	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50523440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50523440&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			130442480	440732022							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51283644	FC(F)(F)c1cc(Oc2nccc3occc23)ccc1-c1cccc2nccn12	InChI=1S/C21H12F3N3O2/c22-21(23,24)16-12-13(29-20-15-7-11-28-18(15)6-8-26-20)4-5-14(16)17-2-1-3-19-25-9-10-27(17)19/h1-12H	ZKXUDWLJTFYOAN-UHFFFAOYSA-N	50523438	CHEMBL4469848	Alpha-2A adrenergic receptor		 5100								ChEMBL	10.1021/acs.jmedchem.9b00351	10.7270/Q2445QWG	30875219			Martini, ML; Liu, J; Ray, C; Yu, X; Huang, XP; Urs, A; Urs, N; McCorvy, JD; Caron, MG; Roth, BL; Jin, J	University of North Carolina at Chapel Hill	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50523438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50523438&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			130442572	440732020							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51295313	COc1ccc(OCCN2CCN(CC2)C(=O)c2cc3ccccc3[nH]2)cc1	InChI=1S/C22H25N3O3/c1-27-18-6-8-19(9-7-18)28-15-14-24-10-12-25(13-11-24)22(26)21-16-17-4-2-3-5-20(17)23-21/h2-9,16,23H,10-15H2,1H3	HAZPAMUWUHDPDA-UHFFFAOYSA-N	50527972	CHEMBL4476784::US11634404, Compound 1	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/acs.jmedchem.0c00424	10.7270/Q28D00QN	32342685			Moritz, AE; Free, RB; Weiner, WS; Akano, EO; Gandhi, D; Abramyan, A; Keck, TM; Ferrer, M; Hu, X; Southall, N; Steiner, J; Aubé, J; Shi, L; Frankowski, KJ; Sibley, DR	National Institute of Neurological Disorders and Stroke	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50527972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50527972&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			27842480	440736554							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51295342	CCCN[C@H]1CCc2nc(N)sc2C1	InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1	FASDKYOPVNHBLU-ZETCQYMHSA-N	50116766	(-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570	Alpha-2A adrenergic receptor		 76								ChEMBL	10.1021/acs.jmedchem.0c00424	10.7270/Q28D00QN	32342685			Moritz, AE; Free, RB; Weiner, WS; Akano, EO; Gandhi, D; Abramyan, A; Keck, TM; Ferrer, M; Hu, X; Southall, N; Steiner, J; Aubé, J; Shi, L; Frankowski, KJ; Sibley, DR	National Institute of Neurological Disorders and Stroke	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	G6L	7CMU	119570	104010405	8356	CHEMBL301265	DB00413			ZINC03781664	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51283450	FC(F)(F)c1cc(Oc2nccc3ccsc23)ccc1-c1cccc2nccn12	InChI=1S/C21H12F3N3OS/c22-21(23,24)16-12-14(28-20-19-13(6-8-26-20)7-11-29-19)4-5-15(16)17-2-1-3-18-25-9-10-27(17)18/h1-12H	BWXKKFQODXKNLQ-UHFFFAOYSA-N	50523439	CHEMBL4466483	Alpha-2A adrenergic receptor		 2600								ChEMBL	10.1021/acs.jmedchem.9b00351	10.7270/Q2445QWG	30875219			Martini, ML; Liu, J; Ray, C; Yu, X; Huang, XP; Urs, A; Urs, N; McCorvy, JD; Caron, MG; Roth, BL; Jin, J	University of North Carolina at Chapel Hill	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50523439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50523439&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			146025727	440732021							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51333228	Cc1nccc2-c3ccc(Br)cc3NC(C)(C)c12	InChI=1S/C15H15BrN2/c1-9-14-12(6-7-17-9)11-5-4-10(16)8-13(11)18-15(14,2)3/h4-8,18H,1-3H3	YBGLIPYAJPOYAD-UHFFFAOYSA-N	50539742	CHEMBL4642292	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1021/acs.jnatprod.9b01107	10.7270/Q2KS6W2R	32227883			Kochanowska-Karamyan, AJ; Araujo, HC; Zhang, X; El-Alfy, A; Carvalho, P; Avery, MA; Holmbo, SD; Magolan, J; Hamann, MT	University of Mississippi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539742&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25235287	442141305							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51345243	COc1cc(cc(OC)c1OC)-c1cncc(c1C)-c1ccc(cc1)N1CCNCC1	InChI=1S/C25H29N3O3/c1-17-21(18-5-7-20(8-6-18)28-11-9-26-10-12-28)15-27-16-22(17)19-13-23(29-2)25(31-4)24(14-19)30-3/h5-8,13-16,26H,9-12H2,1-4H3	RKBYYWVZFBATHQ-UHFFFAOYSA-N	50528194	CHEMBL4517408	Alpha-2A adrenergic receptor			 2180							ChEMBL	10.1021/acs.jmedchem.0c01199	10.7270/Q2VM4GV3	32787083			Smil, D; Wong, JF; Williams, EP; Adamson, RJ; Howarth, A; McLeod, DA; Mamai, A; Kim, S; Wilson, BJ; Kiyota, T; Aman, A; Owen, J; Poda, G; Horiuchi, KY; Kuznetsova, E; Ma, H; Hamblin, JN; Cramp, S; Roberts, OG; Edwards, AM; Uehling, D; Al-Awar, R; Bullock, AN; O'Meara, JA; Isaac, MB	Ontario Institute for Cancer Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528194&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	2Z 	6SZM	134691232	440736776							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51342084	OC(=O)c1cc(cc(c1)-c1ccc(cc1)C1CCNCC1)-c1cn(nn1)-c1ccc(cc1)C(F)(F)F	InChI=1S/C27H23F3N4O2/c28-27(29,30)23-5-7-24(8-6-23)34-16-25(32-33-34)21-13-20(14-22(15-21)26(35)36)18-3-1-17(2-4-18)19-9-11-31-12-10-19/h1-8,13-16,19,31H,9-12H2,(H,35,36)	WYKMWZDXNRNMFC-UHFFFAOYSA-N	50541996	CHEMBL4633982	Alpha-2A adrenergic receptor		 960								ChEMBL	10.1021/acs.jmedchem.0c00745	10.7270/Q20R9SZP	32787142			Jung, YH; Yu, J; Wen, Z; Salmaso, V; Karcz, TP; Phung, NB; Chen, Z; Duca, S; Bennett, JM; Dudas, S; Salvemini, D; Gao, ZG; Cook, DN; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50541996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50541996&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			139406787	442143559							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51383977	COc1ccc2CN3CCC(=C)C[C@]33CCCC[C@@H]3c2c1	InChI=1S/C19H25NO/c1-14-8-10-20-13-15-6-7-16(21-2)11-17(15)18-5-3-4-9-19(18,20)12-14/h6-7,11,18H,1,3-5,8-10,12-13H2,2H3/t18-,19+/m1/s1	BTHSSTHWHHWWSB-MOPGFXCFSA-N	50559170	CHEMBL4777306	Alpha-2A adrenergic receptor		 531								ChEMBL	10.1021/acs.jmedchem.0c01192	10.7270/Q2XD15CH	33111525			Ye, N; Qin, W; Tian, S; Xu, Q; Wold, EA; Zhou, J; Zhen, XC	Soochow University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50559170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50559170&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162643475	461829562							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
370467	Cc1ccc(Cl)c2[nH]c3c(ccc(F)c3c12)C([O-])=O	InChI=1S/C14H9ClFNO2/c1-6-2-4-8(15)13-10(6)11-9(16)5-3-7(14(18)19)12(11)17-13/h2-5,17H,1H3,(H,18,19)/p-1	HPPILTSFNNPAGH-UHFFFAOYSA-M	525279	US11173137, Compound  FA26::US11173137, Compound AK3-98B	Alpha-2A adrenergic receptor		 3000								US Patent		10.7270/Q2HX1GVZ		aid1806091	US11173137	Koster, AK; Du Bois, J; Maduke, MC	The Board of Trustees of the Leland Stanford Junior University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525279&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			163199752	463788946							1	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51377815	C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1	InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m0/s1	UYNVMODNBIQBMV-KKSFZXQISA-N	50007674	(+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::(-)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::4-[(1R,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::4-[(R)-2-(4-Benzyl-piperidin-1-yl)-1-(S)-hydroxy-propyl]-phenol::4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::CHEMBL49623::Ifenprodil::Ifenprodil,(+/-)	Alpha-2A adrenergic receptor		 1600								ChEMBL	10.1021/acs.jmedchem.0c01912	10.7270/Q24T6P14	33426889			Bechthold, E; Schreiber, JA; Lehmkuhl, K; Frehland, B; Schepmann, D; Bernal, FA; Daniliuc, C; Álvarez, I; Garcia, CV; Schmidt, TJ; Seebohm, G; Wünsch, B	Westf&#163;lische Wilhelms-Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007674&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	QEL	4PE5,3QEL,7AQI,5EWJ	6604117	103920944		CHEMBL49623				ZINC00014669	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51377816	C[C@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1	InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m1/s1	UYNVMODNBIQBMV-IIBYNOLFSA-N	50080017	(+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol]::(+/-)-ifenprodil::-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol::4-((1S,2R)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol::4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol::4-[(1S,2R)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::CHEMBL113830::ifenprodil	Alpha-2A adrenergic receptor		 2300								ChEMBL	10.1021/acs.jmedchem.0c01912	10.7270/Q24T6P14	33426889			Bechthold, E; Schreiber, JA; Lehmkuhl, K; Frehland, B; Schepmann, D; Bernal, FA; Daniliuc, C; Álvarez, I; Garcia, CV; Schmidt, TJ; Seebohm, G; Wünsch, B	Westf&#163;lische Wilhelms-Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080017&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11198145	103980208		CHEMBL113830				ZINC03616630	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51377817	C[C@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1	InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21+/m1/s1	UYNVMODNBIQBMV-IERDGZPVSA-N	50557186	CHEMBL493054	Alpha-2A adrenergic receptor		 5500								ChEMBL	10.1021/acs.jmedchem.0c01912	10.7270/Q24T6P14	33426889			Bechthold, E; Schreiber, JA; Lehmkuhl, K; Frehland, B; Schepmann, D; Bernal, FA; Daniliuc, C; Álvarez, I; Garcia, CV; Schmidt, TJ; Seebohm, G; Wünsch, B	Westf&#163;lische Wilhelms-Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50557186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50557186&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12613159	461695954							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51377818	C[C@@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1	InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21+/m0/s1	UYNVMODNBIQBMV-HRAATJIYSA-N	50007677	(+)-threo 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::(-)-threo 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::CHEMBL319706::Ifenprodil	Alpha-2A adrenergic receptor		 6100								ChEMBL	10.1021/acs.jmedchem.0c01912	10.7270/Q24T6P14	33426889			Bechthold, E; Schreiber, JA; Lehmkuhl, K; Frehland, B; Schepmann, D; Bernal, FA; Daniliuc, C; Álvarez, I; Garcia, CV; Schmidt, TJ; Seebohm, G; Wünsch, B	Westf&#163;lische Wilhelms-Universit&#163;t M&#163;nster	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007677&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11771731	103920947		CHEMBL319706				ZINC02559943	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51388790	CC(=O)Nc1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)cc1	InChI=1S/C23H26FN3O3/c1-16(28)25-19-4-6-20(7-5-19)29-14-2-11-27-12-9-17(10-13-27)23-21-8-3-18(24)15-22(21)30-26-23/h3-8,15,17H,2,9-14H2,1H3,(H,25,28)	TVTNBOZUNDIPJR-UHFFFAOYSA-N	50561093	CHEMBL4784373	Alpha-2A adrenergic receptor		 16								ChEMBL	10.1016/j.bmcl.2020.127506	10.7270/Q2CR5Z20	32828898			Huang, L; Gao, L; Zhang, X; Yin, L; Hu, J; Song, T; Chen, Y	Jiangsu Ocean University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50561093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50561093&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			15391752	461831485							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51388791	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone	Alpha-2A adrenergic receptor		 28								ChEMBL	10.1016/j.bmcl.2020.127506	10.7270/Q2CR5Z20	32828898			Huang, L; Gao, L; Zhang, X; Yin, L; Hu, J; Song, T; Chen, Y	Jiangsu Ocean University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252	8871	CHEMBL85	DB00734	96		ZINC00538312	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51388792	CC(=O)Nc1ccc(OCCCCN2CCC(CC2)c2noc3cc(F)ccc23)cc1	InChI=1S/C24H28FN3O3/c1-17(29)26-20-5-7-21(8-6-20)30-15-3-2-12-28-13-10-18(11-14-28)24-22-9-4-19(25)16-23(22)31-27-24/h4-9,16,18H,2-3,10-15H2,1H3,(H,26,29)	TZFKQPVOFBQHAZ-UHFFFAOYSA-N	50561102	CHEMBL4794963	Alpha-2A adrenergic receptor		 193								ChEMBL	10.1016/j.bmcl.2020.127506	10.7270/Q2CR5Z20	32828898			Huang, L; Gao, L; Zhang, X; Yin, L; Hu, J; Song, T; Chen, Y	Jiangsu Ocean University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50561102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50561102&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162672516	461831494							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51400340	CC1COCc2sc(NC(=S)Nc3ccccc3)c(C(=O)OC(C)(C)C)c12	InChI=1S/C20H24N2O3S2/c1-12-10-24-11-14-15(12)16(18(23)25-20(2,3)4)17(27-14)22-19(26)21-13-8-6-5-7-9-13/h5-9,12H,10-11H2,1-4H3,(H2,21,22,26)	CRHRLCOJLBNAFG-UHFFFAOYSA-N	50565667	CHEMBL4795943	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.ejmech.2020.112387	10.7270/Q25M69GN	32829163			Xue, D; Chen, W; Neamati, N	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565667&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162673706	461686005							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51400341	C[C@@H](NC(=S)Nc1sc2COCCc2c1C(=O)OC(C)(C)C)c1ccccc1	InChI=1S/C21H26N2O3S2/c1-13(14-8-6-5-7-9-14)22-20(27)23-18-17(19(24)26-21(2,3)4)15-10-11-25-12-16(15)28-18/h5-9,13H,10-12H2,1-4H3,(H2,22,23,27)/t13-/m1/s1	SAZZQHLXFBHGAI-CYBMUJFWSA-N	50565686	CHEMBL4787874	Alpha-2A adrenergic receptor		>10000								ChEMBL	10.1016/j.ejmech.2020.112387	10.7270/Q25M69GN	32829163			Xue, D; Chen, W; Neamati, N	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565686&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162668484	461686024							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51410016	[O-][N+](=O)C1=Cc2cc(I)ccc2OC1C(F)(F)F	InChI=1S/C10H5F3INO3/c11-10(12,13)9-7(15(16)17)4-5-3-6(14)1-2-8(5)18-9/h1-4,9H	OPOOLSURVZPHRO-UHFFFAOYSA-N	50569548	CHEMBL4875858	Alpha-2A adrenergic receptor		 4800								ChEMBL	10.1016/j.bmcl.2021.128008	10.7270/Q2C2516Q	33831560			Jung, YH; Jain, S; Gopinatth, V; Phung, NB; Gao, ZG; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50569548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50569548&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			163198500	471059693							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51410017	C[Si](C)(C)C#Cc1ccc2OC(C(=Cc2c1)[N+]([O-])=O)C(F)(F)F	InChI=1S/C15H14F3NO3Si/c1-23(2,3)7-6-10-4-5-13-11(8-10)9-12(19(20)21)14(22-13)15(16,17)18/h4-5,8-9,14H,1-3H3	BXRYWEUVCDCBRM-UHFFFAOYSA-N	50569550	CHEMBL4851349	Alpha-2A adrenergic receptor		 4700								ChEMBL	10.1016/j.bmcl.2021.128008	10.7270/Q2C2516Q	33831560			Jung, YH; Jain, S; Gopinatth, V; Phung, NB; Gao, ZG; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50569550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50569550&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164614469	471059695							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51410018	CC(=O)NCC#Cc1ccc2OC(C(=Cc2c1)[N+]([O-])=O)C(F)(F)F	InChI=1S/C15H11F3N2O4/c1-9(21)19-6-2-3-10-4-5-13-11(7-10)8-12(20(22)23)14(24-13)15(16,17)18/h4-5,7-8,14H,6H2,1H3,(H,19,21)	OVXPWLPUGMYBAI-UHFFFAOYSA-N	50569555	CHEMBL4848838	Alpha-2A adrenergic receptor		 2200								ChEMBL	10.1016/j.bmcl.2021.128008	10.7270/Q2C2516Q	33831560			Jung, YH; Jain, S; Gopinatth, V; Phung, NB; Gao, ZG; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50569555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50569555&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164618319	471059700							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51410019	CC(C)(C)OC(=O)NCC#Cc1ccc2OC(C(=Cc2c1)[N+]([O-])=O)C(F)(F)F	InChI=1S/C18H17F3N2O5/c1-17(2,3)28-16(24)22-8-4-5-11-6-7-14-12(9-11)10-13(23(25)26)15(27-14)18(19,20)21/h6-7,9-10,15H,8H2,1-3H3,(H,22,24)	LIKDQKPQARRCAR-UHFFFAOYSA-N	50569557	CHEMBL4856060	Alpha-2A adrenergic receptor		 940								ChEMBL	10.1016/j.bmcl.2021.128008	10.7270/Q2C2516Q	33831560			Jung, YH; Jain, S; Gopinatth, V; Phung, NB; Gao, ZG; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50569557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50569557&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164609730	471059702							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51410020	OC(=O)c1ccc(cc1)C#Cc1ccc2OC(C(=Cc2c1)[N+]([O-])=O)C(F)(F)F	InChI=1S/C19H10F3NO5/c20-19(21,22)17-15(23(26)27)10-14-9-12(5-8-16(14)28-17)2-1-11-3-6-13(7-4-11)18(24)25/h3-10,17H,(H,24,25)	YHEJLDMRDBHXIJ-UHFFFAOYSA-N	50569559	CHEMBL4857492	Alpha-2A adrenergic receptor		 1800								ChEMBL	10.1016/j.bmcl.2021.128008	10.7270/Q2C2516Q	33831560			Jung, YH; Jain, S; Gopinatth, V; Phung, NB; Gao, ZG; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50569559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50569559&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164615845	471059704							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51410021	[O-][N+](=O)C1=Cc2cc(ccc2OC1C(F)(F)F)C#CCN1C(=O)c2ccccc2C1=O	InChI=1S/C21H11F3N2O5/c22-21(23,24)18-16(26(29)30)11-13-10-12(7-8-17(13)31-18)4-3-9-25-19(27)14-5-1-2-6-15(14)20(25)28/h1-2,5-8,10-11,18H,9H2	ZVNIAPHCOMMUCZ-UHFFFAOYSA-N	50569565	CHEMBL4845850	Alpha-2A adrenergic receptor		 650								ChEMBL	10.1016/j.bmcl.2021.128008	10.7270/Q2C2516Q	33831560			Jung, YH; Jain, S; Gopinatth, V; Phung, NB; Gao, ZG; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50569565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50569565&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164609539	471059710							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51402058	OC(=O)c1cc(-c2ccc(cc2)C2CCN(CC2)C=O)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F	InChI=1S/C30H24F3NO3/c31-30(32,33)26-8-5-20(6-9-26)23-7-10-27-24(15-23)16-25(29(36)37)17-28(27)22-3-1-19(2-4-22)21-11-13-34(18-35)14-12-21/h1-10,15-18,21H,11-14H2,(H,36,37)	JPGUEKOOSRXUSX-UHFFFAOYSA-N	50566377	CHEMBL4848380	Alpha-2A adrenergic receptor		 3970								ChEMBL	10.1021/acs.jmedchem.1c00164	10.7270/Q2BZ69SP	33787273			Jung, YH; Salmaso, V; Wen, Z; Bennett, JM; Phung, NB; Lieberman, DI; Gopinatth, V; Randle, JCR; Chen, Z; Salvemini, D; Karcz, TP; Cook, DN; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50566377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50566377&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164585473	471056522							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51420266	CC(C)C[C@@H](N)C(=O)Nc1ccc(-c2cnco2)c(OC(F)F)c1	InChI=1S/C16H19F2N3O3/c1-9(2)5-12(19)15(22)21-10-3-4-11(14-7-20-8-23-14)13(6-10)24-16(17)18/h3-4,6-9,12,16H,5,19H2,1-2H3,(H,21,22)/t12-/m1/s1	GCTFTMWXZFLTRR-GFCCVEGCSA-N	50573682	CHEMBL4872886	Alpha-2A adrenergic receptor			>30000							ChEMBL	10.1021/acs.jmedchem.1c00472	10.7270/Q2WQ07KF	34270254			Hartz, RA; Ahuja, VT; Nara, SJ; Kumar, CMV; Brown, JM; Bristow, LJ; Rajamani, R; Muckelbauer, JK; Camac, D; Kiefer, SE; Hunihan, L; Gulianello, M; Lewis, M; Easton, A; Lippy, JS; Surti, N; Pattipati, SN; Dokania, M; Elavazhagan, S; Dandapani, K; Hamman, BD; Allen, J; Kostich, W; Bronson, JJ; Macor, JE; Dzierba, CD	Bristol Myers Squibb Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50573682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50573682&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	5QI	7RJ8	86582964	471063827							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51434027	Fc1cccc(c1)S(=O)(=O)n1ccc2c(nc3ccccc3c12)N1CCNCC1	InChI=1S/C21H19FN4O2S/c22-15-4-3-5-16(14-15)29(27,28)26-11-8-18-20(26)17-6-1-2-7-19(17)24-21(18)25-12-9-23-10-13-25/h1-8,11,14,23H,9-10,12-13H2	QNKGTIWNFNPEJL-UHFFFAOYSA-N	50579346	CHEMBL4867565	Alpha-2A adrenergic receptor		 110								ChEMBL	10.1021/acs.jmedchem.1c00224	10.7270/Q2X3528B	34467765			Zajdel, P; Grychowska, K; Mogilski, S; Kurczab, R; Satała, G; Bugno, R; Kos, T; Gołębiowska, J; Malikowska-Racia, N; Nikiforuk, A; Chaumont-Dubel, S; Bantreil, X; Pawłowski, M; Martinez, J; Subra, G; Lamaty, F; Marin, P; Bojarski, AJ; Popik, P	Jagiellonian University Medical College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50579346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50579346&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			90469115	471055469							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450970	NCCCCN(C[C@H]1Cc2ccccc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C23H32N4/c24-12-3-4-14-27(22-11-5-9-18-10-6-13-25-23(18)22)17-21-15-19-7-1-2-8-20(19)16-26-21/h1-2,6-8,10,13,21-22,26H,3-5,9,11-12,14-17,24H2/t21-,22+/m1/s1	MYCKNKHATQGHEV-YADHBBJMSA-N	50443541	CHEMBL3091687	Alpha-2A adrenergic receptor			 3700							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50443541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50443541&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345320	194941437		CHEMBL3091687					1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450971	NCCCCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C22H31N5/c23-10-1-2-13-27(21-9-3-6-17-7-4-12-25-22(17)21)16-19-14-20-18(15-26-19)8-5-11-24-20/h4-5,7-8,11-12,19,21,26H,1-3,6,9-10,13-16,23H2/t19-,21+/m1/s1	AJBIIZLEMNVANQ-CTNGQTDRSA-N	50585788	CHEMBL5070958	Alpha-2A adrenergic receptor			 11000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585788	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585788&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			163196369	476021875							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450972	NCCCCN(C[C@H]1Cc2cccnc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C22H31N5/c23-10-1-2-13-27(21-9-3-6-17-7-4-12-25-22(17)21)16-19-14-18-8-5-11-24-20(18)15-26-19/h4-5,7-8,11-12,19,21,26H,1-3,6,9-10,13-16,23H2/t19-,21+/m1/s1	SASWWPISKHTFAO-CTNGQTDRSA-N	50585790	CHEMBL5076569	Alpha-2A adrenergic receptor			 1300							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585790&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166626034	476021877							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450973	CN(CCCCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)C1CCC(F)(F)CC1	InChI=1S/C29H41F2N5/c1-35(25-11-13-29(30,31)14-12-25)17-2-3-18-36(27-10-4-7-22-8-5-16-33-28(22)27)21-24-19-26-23(20-34-24)9-6-15-32-26/h5-6,8-9,15-16,24-25,27,34H,2-4,7,10-14,17-21H2,1H3/t24-,27+/m1/s1	OSKSLFQSLKWAIH-SQHAQQRYSA-N	50585805	CHEMBL5093818	Alpha-2A adrenergic receptor			 810							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585805&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155807735	476021892							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450974	C(CCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)CNC1CCOCC1	InChI=1S/C27H39N5O/c1(12-28-23-10-16-33-17-11-23)2-15-32(26-9-3-6-21-7-4-14-30-27(21)26)20-24-18-25-22(19-31-24)8-5-13-29-25/h4-5,7-8,13-14,23-24,26,28,31H,1-3,6,9-12,15-20H2/t24-,26+/m1/s1	POWOJVYGOJPOQL-RSXGOPAZSA-N	50585806	CHEMBL5085511	Alpha-2A adrenergic receptor			>30000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585806&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166631293	476021893							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450975	CN(CCCCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)C1CCOCC1	InChI=1S/C28H41N5O/c1-32(25-11-17-34-18-12-25)15-2-3-16-33(27-10-4-7-22-8-5-14-30-28(22)27)21-24-19-26-23(20-31-24)9-6-13-29-26/h5-6,8-9,13-14,24-25,27,31H,2-4,7,10-12,15-21H2,1H3/t24-,27+/m1/s1	IEQLWCFKWYLMAM-SQHAQQRYSA-N	50585807	CHEMBL5077132	Alpha-2A adrenergic receptor			 28000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585807&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166626056	476021894							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450976	C(CCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)CNC1COC1	InChI=1S/C25H35N5O/c1(10-26-22-17-31-18-22)2-13-30(24-9-3-6-19-7-4-12-28-25(19)24)16-21-14-23-20(15-29-21)8-5-11-27-23/h4-5,7-8,11-12,21-22,24,26,29H,1-3,6,9-10,13-18H2/t21-,24+/m1/s1	HCFZOYBEELAHRR-QPPBQGQZSA-N	50585808	CHEMBL5083458	Alpha-2A adrenergic receptor			 24000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585808&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166627357	476021895							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450977	C(CCN1CCOCC1)CN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C26H37N5O/c1(12-30-14-16-32-17-15-30)2-13-31(25-9-3-6-21-7-4-11-28-26(21)25)20-23-18-24-22(19-29-23)8-5-10-27-24/h4-5,7-8,10-11,23,25,29H,1-3,6,9,12-20H2/t23-,25+/m1/s1	STAHMXIYSLAGBJ-NOZRDPDXSA-N	50585811	CHEMBL5082142	Alpha-2A adrenergic receptor			 620							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585811&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166629813	476021898							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51450978	NCCCCN(Cc1nc2ccccc2[nH]1)[C@H]1CCCc2cccnc12	InChI=1S/C21H27N5/c22-12-3-4-14-26(15-20-24-17-9-1-2-10-18(17)25-20)19-11-5-7-16-8-6-13-23-21(16)19/h1-2,6,8-10,13,19H,3-5,7,11-12,14-15,22H2,(H,24,25)/t19-/m0/s1	WVLHHLRVNDMIAR-IBGZPJMESA-N	50315305	(S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-aminobutyl)-5,6,7,8-tetrahydroquinolin-8-amine::(S)-N1-((1H-benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine::CHEMBL518924	Alpha-2A adrenergic receptor			>30000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50315305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50315305&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11256587	104149666		CHEMBL518924				ZINC33359232	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51468659	CN1CCN(CC1(C)C)[C@@H]1C[C@H](c2ccc(Cl)cc12)c1ccccc1	InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3/t19-,21+/m0/s1	BYPMJBXPNZMNQD-PZJWPPBQSA-N	50547397	LU-31-130::Lu 31-130::Zicronapine	Alpha-2A adrenergic receptor		 560								ChEMBL		10.7270/Q2P27346	35809818			Gjervig Jensen, K; Tornby Christoffersen, C; Graulund Hvenegaard, M; Didriksen, M; Jørgensen, M	H. Lundbeck A/S	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50547397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50547397&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11465618	461691160							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51468660	[2H]c1c([2H])c([2H])c([C@@H]2C[C@@H](N3CCNC(C)(C)C3)c3cc(Cl)ccc23)c([2H])c1[2H]	InChI=1S/C21H25ClN2/c1-21(2)14-24(11-10-23-21)20-13-18(15-6-4-3-5-7-15)17-9-8-16(22)12-19(17)20/h3-9,12,18,20,23H,10-11,13-14H2,1-2H3/t18-,20+/m0/s1/i3D,4D,5D,6D,7D	FBCSWIXKXHSYBN-LSQWYULJSA-N	50592735	CHEMBL5201983	Alpha-2A adrenergic receptor		 2500								ChEMBL		10.7270/Q2P27346	35809818			Gjervig Jensen, K; Tornby Christoffersen, C; Graulund Hvenegaard, M; Didriksen, M; Jørgensen, M	H. Lundbeck A/S	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50592735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50592735&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			89287174	482603587							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51493145	CCCCCNC(=O)\N=C(/N)NCCCc1sc(N)nc1C	InChI=1S/C14H26N6OS/c1-3-4-5-8-18-14(21)20-12(15)17-9-6-7-11-10(2)19-13(16)22-11/h3-9H2,1-2H3,(H2,16,19)(H4,15,17,18,20,21)	ZRQMUCDHVVOENY-UHFFFAOYSA-N	50568740	CHEMBL4860528	Alpha-2A adrenergic receptor					 891					ChEMBL		10.7270/Q2MP57CT	34110814			Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A	University of Regensburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568740&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164612037	471058885							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51493146	OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCCCCNC(=O)\N=C(/N)NCCCc1nnc(N)s1	InChI=1S/C12H23N7OS.2C2HF3O2/c1-2-3-4-7-16-12(20)17-10(13)15-8-5-6-9-18-19-11(14)21-9;2*3-2(4,5)1(6)7/h2-8H2,1H3,(H2,14,19)(H4,13,15,16,17,20);2*(H,6,7)	WPIVDYCRNVUSIY-UHFFFAOYSA-N	50601551	CHEMBL5207281	Alpha-2A adrenergic receptor					 4898					ChEMBL		10.7270/Q2MP57CT	34110814			Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A	University of Regensburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601551&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168295704	482612403							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51493147	OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.N\C(NCCCc1nnc(N)s1)=N/C(=O)NCc1ccccc1	InChI=1S/C14H19N7OS.2C2HF3O2/c15-12(17-8-4-7-11-20-21-13(16)23-11)19-14(22)18-9-10-5-2-1-3-6-10;2*3-2(4,5)1(6)7/h1-3,5-6H,4,7-9H2,(H2,16,21)(H4,15,17,18,19,22);2*(H,6,7)	JQNCPAZRLLSTTQ-UHFFFAOYSA-N	50601567	CHEMBL5206565	Alpha-2A adrenergic receptor					 1259					ChEMBL		10.7270/Q2MP57CT	34110814			Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A	University of Regensburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601567&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168296523	482612419							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51493148	Cl.Cl.C[C@@H](NC(=O)\N=C(/N)NCCCc1ncn[nH]1)c1ccccc1	InChI=1S/C15H21N7O.2ClH/c1-11(12-6-3-2-4-7-12)20-15(23)21-14(16)17-9-5-8-13-18-10-19-22-13;;/h2-4,6-7,10-11H,5,8-9H2,1H3,(H,18,19,22)(H4,16,17,20,21,23);2*1H/t11-;;/m1../s1	XRYVFZXIDAULKH-NVJADKKVSA-N	50601574	CHEMBL5201074	Alpha-2A adrenergic receptor					 851					ChEMBL		10.7270/Q2MP57CT	34110814			Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A	University of Regensburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601574&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168290234	482612426							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51493149	CCCCCNC(=O)\N=C(/N)NCCCc1sc(N)nc1C	InChI=1S/C14H26N6OS/c1-3-4-5-8-18-14(21)20-12(15)17-9-6-7-11-10(2)19-13(16)22-11/h3-9H2,1-2H3,(H2,16,19)(H4,15,17,18,20,21)	ZRQMUCDHVVOENY-UHFFFAOYSA-N	50568740	CHEMBL4860528	Alpha-2A adrenergic receptor				 0.600000						ChEMBL		10.7270/Q2MP57CT	34110814			Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A	University of Regensburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568740&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164612037	471058885							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51493150	OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCCCCNC(=O)\N=C(/N)NCCCc1nnc(N)s1	InChI=1S/C12H23N7OS.2C2HF3O2/c1-2-3-4-7-16-12(20)17-10(13)15-8-5-6-9-18-19-11(14)21-9;2*3-2(4,5)1(6)7/h2-8H2,1H3,(H2,14,19)(H4,13,15,16,17,20);2*(H,6,7)	WPIVDYCRNVUSIY-UHFFFAOYSA-N	50601551	CHEMBL5207281	Alpha-2A adrenergic receptor				 0.600000						ChEMBL		10.7270/Q2MP57CT	34110814			Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A	University of Regensburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601551&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168295704	482612403							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51493151	OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.N\C(NCCCc1nnc(N)s1)=N/C(=O)NCc1ccccc1	InChI=1S/C14H19N7OS.2C2HF3O2/c15-12(17-8-4-7-11-20-21-13(16)23-11)19-14(22)18-9-10-5-2-1-3-6-10;2*3-2(4,5)1(6)7/h1-3,5-6H,4,7-9H2,(H2,16,21)(H4,15,17,18,19,22);2*(H,6,7)	JQNCPAZRLLSTTQ-UHFFFAOYSA-N	50601567	CHEMBL5206565	Alpha-2A adrenergic receptor				 0.600000						ChEMBL		10.7270/Q2MP57CT	34110814			Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A	University of Regensburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601567&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168296523	482612419							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51493152	Cl.Cl.C[C@@H](NC(=O)\N=C(/N)NCCCc1ncn[nH]1)c1ccccc1	InChI=1S/C15H21N7O.2ClH/c1-11(12-6-3-2-4-7-12)20-15(23)21-14(16)17-9-5-8-13-18-10-19-22-13;;/h2-4,6-7,10-11H,5,8-9H2,1H3,(H,18,19,22)(H4,16,17,20,21,23);2*1H/t11-;;/m1../s1	XRYVFZXIDAULKH-NVJADKKVSA-N	50601574	CHEMBL5201074	Alpha-2A adrenergic receptor				 0.600000						ChEMBL		10.7270/Q2MP57CT	34110814			Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A	University of Regensburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601574&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168290234	482612426							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51500767	CS(=O)(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12	InChI=1S/C17H15N5O3S/c1-26(23,24)14-6-4-12(5-7-14)15-10-19-17(22-11-20-21-16(15)22)18-9-13-3-2-8-25-13/h2-8,10-11H,9H2,1H3,(H,18,19)	DYIRSNMPIZZNBK-UHFFFAOYSA-N	225230	EED226::US11013745, Compound EED226	Alpha-2A adrenergic receptor			 15000							ChEMBL		10.7270/Q2Z323QR	35352560			Huang, Y; Sendzik, M; Zhang, J; Gao, Z; Sun, Y; Wang, L; Gu, J; Zhao, K; Yu, Z; Zhang, L; Zhang, Q; Blanz, J; Chen, Z; Dubost, V; Fang, D; Feng, L; Fu, X; Kiffe, M; Li, L; Luo, F; Luo, X; Mi, Y; Mistry, P; Pearson, D; Piaia, A; Scheufler, C; Terranova, R; Weiss, A; Zeng, J; Zhang, H; Zhang, J; Zhao, M; Dillon, MP; Jeay, S; Qi, W; Moggs, J; Pissot-Soldermann, C; Li, E; Atadja, P; Lingel, A; Oyang, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=225230	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=225230&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	73K	5WUK,5GSA	123132228	336292426							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51500768	COc1cccc(F)c1CNc1ccc(-c2cnc(C)nc2C)c2nncn12	InChI=1S/C20H19FN6O/c1-12-15(9-22-13(2)25-12)14-7-8-19(27-11-24-26-20(14)27)23-10-16-17(21)5-4-6-18(16)28-3/h4-9,11,23H,10H2,1-3H3	OHVGZODROPSVRZ-UHFFFAOYSA-N	50604672	CHEMBL5178464	Alpha-2A adrenergic receptor			 9500							ChEMBL		10.7270/Q2Z323QR	35352560			Huang, Y; Sendzik, M; Zhang, J; Gao, Z; Sun, Y; Wang, L; Gu, J; Zhao, K; Yu, Z; Zhang, L; Zhang, Q; Blanz, J; Chen, Z; Dubost, V; Fang, D; Feng, L; Fu, X; Kiffe, M; Li, L; Luo, F; Luo, X; Mi, Y; Mistry, P; Pearson, D; Piaia, A; Scheufler, C; Terranova, R; Weiss, A; Zeng, J; Zhang, H; Zhang, J; Zhao, M; Dillon, MP; Jeay, S; Qi, W; Moggs, J; Pissot-Soldermann, C; Li, E; Atadja, P; Lingel, A; Oyang, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50604672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50604672&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132256889	482615523							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51500769	Cc1ncccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12	InChI=1S/C20H17FN6O/c1-12-13(3-2-7-22-12)16-10-24-20(27-11-25-26-19(16)27)23-9-15-14-6-8-28-18(14)5-4-17(15)21/h2-5,7,10-11H,6,8-9H2,1H3,(H,23,24)	XLIBABIFOBYHSV-UHFFFAOYSA-N	291687	N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine::US11207325, Example 2::US9580437, Example 2	Alpha-2A adrenergic receptor			 9600							ChEMBL		10.7270/Q2Z323QR	35352560			Huang, Y; Sendzik, M; Zhang, J; Gao, Z; Sun, Y; Wang, L; Gu, J; Zhao, K; Yu, Z; Zhang, L; Zhang, Q; Blanz, J; Chen, Z; Dubost, V; Fang, D; Feng, L; Fu, X; Kiffe, M; Li, L; Luo, F; Luo, X; Mi, Y; Mistry, P; Pearson, D; Piaia, A; Scheufler, C; Terranova, R; Weiss, A; Zeng, J; Zhang, H; Zhang, J; Zhao, M; Dillon, MP; Jeay, S; Qi, W; Moggs, J; Pissot-Soldermann, C; Li, E; Atadja, P; Lingel, A; Oyang, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000068&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291687&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	EJR	7QK4,6YVJ	121412508	381611988							1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7EJ0,7EJ8,7EJA,7EJK,7W6P,7W7E	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51545182	CCCN1CCN(CC1)c1ccc2CCCC(N(C)C(=O)OCc3ccccc3)c2c1	InChI=1S/C26H35N3O2/c1-3-14-28-15-17-29(18-16-28)23-13-12-22-10-7-11-25(24(22)19-23)27(2)26(30)31-20-21-8-5-4-6-9-21/h4-6,8-9,12-13,19,25H,3,7,10-11,14-18,20H2,1-2H3	PBFDUYRSNDQIDN-UHFFFAOYSA-N	50621475	CHEMBL5403404	Alpha-2A adrenergic receptor	Homo sapiens	 1031								ChEMBL	10.1016/j.ejmech.2022.114696	10.7270/Q2F76HXN	36088757			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50621475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50621475&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51546455	[11CH3]OCc1cccnc1N1CCN(C[C@H]2COc3ccccc3O2)CC1	InChI=1S/C20H25N3O3/c1-24-14-16-5-4-8-21-20(16)23-11-9-22(10-12-23)13-17-15-25-18-6-2-3-7-19(18)26-17/h2-8,17H,9-15H2,1H3/t17-/m0/s1/i1-1	VGIYMYGMVXPMKV-GWDMYEQXSA-N	50621980	(11C)ORM-13070::11C-ORM-13070::11c-orm-13070::ORM-13070 C-11::Orm-13070 c-11	Alpha-2A adrenergic receptor	Homo sapiens			 109						ChEMBL	10.1021/acs.jmedchem.2c01965	10.7270/Q29C72TF	37145921			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50621980	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50621980&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51551514	COc1ccccc1N1CCN(CCCNC(=O)Nc2ccccc2-c2ccccc2)CC1	InChI=1S/C27H32N4O2/c1-33-26-15-8-7-14-25(26)31-20-18-30(19-21-31)17-9-16-28-27(32)29-24-13-6-5-12-23(24)22-10-3-2-4-11-22/h2-8,10-15H,9,16-21H2,1H3,(H2,28,29,32)	IBNWNWKMISLVQT-UHFFFAOYSA-N	50624206	CHEMBL5400232	Alpha-2A adrenergic receptor	Homo sapiens	 28								ChEMBL	10.1021/acs.jmedchem.3c00537	10.7270/Q2DB868W	37450764			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50624206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50624206&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51551515	COCCOCCOc1ccc(NC(=O)NCCCN2CCN(CC2)c2ccccc2OC)c(c1)-c1ccccc1	InChI=1S/C32H42N4O5/c1-38-21-22-40-23-24-41-27-13-14-29(28(25-27)26-9-4-3-5-10-26)34-32(37)33-15-8-16-35-17-19-36(20-18-35)30-11-6-7-12-31(30)39-2/h3-7,9-14,25H,8,15-24H2,1-2H3,(H2,33,34,37)	HZBAKQLOTJCSJX-UHFFFAOYSA-N	50624212	CHEMBL5422870	Alpha-2A adrenergic receptor	Homo sapiens	 410								ChEMBL	10.1021/acs.jmedchem.3c00537	10.7270/Q2DB868W	37450764			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50624212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50624212&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51551516	COc1ccccc1N1CCN(CCCNC(=O)Nc2ccccc2-c2ccc(cc2)-c2ccccc2)CC1	InChI=1S/C33H36N4O2/c1-39-32-15-8-7-14-31(32)37-24-22-36(23-25-37)21-9-20-34-33(38)35-30-13-6-5-12-29(30)28-18-16-27(17-19-28)26-10-3-2-4-11-26/h2-8,10-19H,9,20-25H2,1H3,(H2,34,35,38)	VGUQUIYJFQJLRU-UHFFFAOYSA-N	50624217	CHEMBL5394229	Alpha-2A adrenergic receptor	Homo sapiens	 150								ChEMBL	10.1021/acs.jmedchem.3c00537	10.7270/Q2DB868W	37450764			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50624217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50624217&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51551517	COc1ccccc1N1CCN(CCCNC(=O)NCc2ccccc2-c2ccccc2)CC1	InChI=1S/C28H34N4O2/c1-34-27-15-8-7-14-26(27)32-20-18-31(19-21-32)17-9-16-29-28(33)30-22-24-12-5-6-13-25(24)23-10-3-2-4-11-23/h2-8,10-15H,9,16-22H2,1H3,(H2,29,30,33)	RGPTYLNPCNVHNC-UHFFFAOYSA-N	50624218	CHEMBL5425252	Alpha-2A adrenergic receptor	Homo sapiens	 120								ChEMBL	10.1021/acs.jmedchem.3c00537	10.7270/Q2DB868W	37450764			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50624218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50624218&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51551518	COc1ccc(c(CNC(=O)NCCCN2CCN(CC2)c2ccccc2OC)c1)-c1ccccc1	InChI=1S/C29H36N4O3/c1-35-25-13-14-26(23-9-4-3-5-10-23)24(21-25)22-31-29(34)30-15-8-16-32-17-19-33(20-18-32)27-11-6-7-12-28(27)36-2/h3-7,9-14,21H,8,15-20,22H2,1-2H3,(H2,30,31,34)	HEPZPDOHSGVKLD-UHFFFAOYSA-N	50624223	CHEMBL5403204	Alpha-2A adrenergic receptor	Homo sapiens	 200								ChEMBL	10.1021/acs.jmedchem.3c00537	10.7270/Q2DB868W	37450764			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50624223	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50624223&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51576839	CC(C)(C)Cc1c(sc(N)c1C(=O)c1ccc(Cl)cc1)C#Cc1ccc(F)c(F)c1	InChI=1S/C24H20ClF2NOS/c1-24(2,3)13-17-20(11-5-14-4-10-18(26)19(27)12-14)30-23(28)21(17)22(29)15-6-8-16(25)9-7-15/h4,6-10,12H,13,28H2,1-3H3	GKIHDPUKDDKVKP-UHFFFAOYSA-N	50634556	CHEMBL5398701	Alpha-2A adrenergic receptor	Homo sapiens	 8000								ChEMBL	10.1021/acsmedchemlett.3c00315	10.7270/Q22F7SX0	38116442			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50634556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50634556&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51566586	CN(C)CCc1c[nH]c2ccccc12	InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3	DMULVCHRPCFFGV-UHFFFAOYSA-N	50026868	2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::WO2023019367, Compound DMT	Alpha-2A adrenergic receptor	Homo sapiens		 3030							ChEMBL	10.1021/acsmedchemlett.3c00143	10.7270/Q26Q22P8	37736183			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026868&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6089	103936452	28969	CHEMBL12420	DB01488	141	C08302	ZINC00897457	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51566587	CN(C)CCc1c[nH]c2ccccc12	InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3	DMULVCHRPCFFGV-UHFFFAOYSA-N	50026868	2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::WO2023019367, Compound DMT	Alpha-2A adrenergic receptor	Homo sapiens		 2220							ChEMBL	10.1021/acsmedchemlett.3c00143	10.7270/Q26Q22P8	37736183			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026868&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6089	103936452	28969	CHEMBL12420	DB01488	141	C08302	ZINC00897457	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51566620	CN(C)CCc1c[nH]c2ccccc12	InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3	DMULVCHRPCFFGV-UHFFFAOYSA-N	50026868	2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::WO2023019367, Compound DMT	Alpha-2A adrenergic receptor	Homo sapiens	 1520								ChEMBL	10.1021/acsmedchemlett.3c00143	10.7270/Q26Q22P8	37736183			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026868&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6089	103936452	28969	CHEMBL12420	DB01488	141	C08302	ZINC00897457	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51566621	CN(C)CCc1c[nH]c2ccccc12	InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3	DMULVCHRPCFFGV-UHFFFAOYSA-N	50026868	2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::WO2023019367, Compound DMT	Alpha-2A adrenergic receptor	Homo sapiens	 1110								ChEMBL	10.1021/acsmedchemlett.3c00143	10.7270/Q26Q22P8	37736183			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026868&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6089	103936452	28969	CHEMBL12420	DB01488	141	C08302	ZINC00897457	1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51542521	OC(=O)c1cc(-c2ccc(cc2)C2(O)C[C@H]3CNC[C@@H]3C2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F	InChI=1S/C31H26F3NO3/c32-31(33,34)26-8-1-18(2-9-26)20-5-10-27-21(11-20)12-22(29(36)37)13-28(27)19-3-6-25(7-4-19)30(38)14-23-16-35-17-24(23)15-30/h1-13,23-24,35,38H,14-17H2,(H,36,37)/t23-,24-/m0/s1	FULSVSNRHDJVLM-ZEQRLZLVSA-N	50620476	CHEMBL5404195	Alpha-2A adrenergic receptor	Homo sapiens	 5700								ChEMBL	10.1021/acs.jmedchem.3c00664	10.7270/Q2WS8ZNR	37382926			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50620476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50620476&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51533614	CCN(CC)CCCC(C)Nc1cnc(cn1)C(=O)Nc1ccc(Cl)c2cccnc12	InChI=1S/C23H29ClN6O/c1-4-30(5-2)13-7-8-16(3)28-21-15-26-20(14-27-21)23(31)29-19-11-10-18(24)17-9-6-12-25-22(17)19/h6,9-12,14-16H,4-5,7-8,13H2,1-3H3,(H,27,28)(H,29,31)	KRUQRZWHJYOOJH-UHFFFAOYSA-N	50616867	CHEMBL5395401	Alpha-2A adrenergic receptor	Homo sapiens	 2738								ChEMBL	10.1021/acs.jmedchem.2c01769	10.7270/Q28D01MQ	36692906			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50616867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50616867&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51533615	CCN(CC)CCCC(C)Nc1cnc(cn1)C(=O)Nc1cc(F)cc2cccnc12	InChI=1S/C23H29FN6O/c1-4-30(5-2)11-7-8-16(3)28-21-15-26-20(14-27-21)23(31)29-19-13-18(24)12-17-9-6-10-25-22(17)19/h6,9-10,12-16H,4-5,7-8,11H2,1-3H3,(H,27,28)(H,29,31)	DATRLTNBZWRBPI-UHFFFAOYSA-N	50616870	CHEMBL5431371	Alpha-2A adrenergic receptor	Homo sapiens	 673								ChEMBL	10.1021/acs.jmedchem.2c01769	10.7270/Q28D01MQ	36692906			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50616870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50616870&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1						
51536492	C(CN1CCN(CC1)c1ccccn1)Cc1nc2ccccc2s1	InChI=1S/C19H22N4S/c1-2-7-17-16(6-1)21-19(24-17)9-5-11-22-12-14-23(15-13-22)18-8-3-4-10-20-18/h1-4,6-8,10H,5,9,11-15H2	KZVXSSLUUGFVFR-UHFFFAOYSA-N	50618106	CHEMBL5400876	Alpha-2A adrenergic receptor	Homo sapiens	 356								ChEMBL	10.1021/acs.jmedchem.3c00734	10.7270/Q2XP7999	37646374			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50618106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9124&target=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50618106&enzyme=Alpha-2A+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV	7W7E,7W6P,7EJK,7EJA,7EJ8,7EJ0	Alpha-2A adrenergic receptor	ADA2A_HUMAN	P08913	B0LPF6 Q2I8G2 Q2XN99 Q86TH8 Q9BZK1